diff --git a/alembic/script/revision.py b/alembic/script/revision.py
index c3108e98..f68fc954 100644
--- a/alembic/script/revision.py
+++ b/alembic/script/revision.py
@@ -45,7 +45,7 @@
 _TR = TypeVar("_TR", bound=Optional[_RevisionOrStr])
 
 _relative_destination = re.compile(r"(?:(.+?)@)?(\w+)?((?:\+|-)\d+)")
-_revision_illegal_chars = ["@", "-", "+"]
+_revision_illegal_chars = ["@", "-", "+", ":"]
 
 
 class _CollectRevisionsProtocol(Protocol):