diff --git a/mocks/pkg/dicomio/mock_reader.go b/mocks/pkg/dicomio/mock_reader.go
index e7b239ce..9f060a4b 100644
--- a/mocks/pkg/dicomio/mock_reader.go
+++ b/mocks/pkg/dicomio/mock_reader.go
@@ -289,3 +289,17 @@ func (mr *MockReaderMockRecorder) SetCodingSystem(cs interface{}) *gomock.Call {
 	mr.mock.ctrl.T.Helper()
 	return mr.mock.ctrl.RecordCallWithMethodType(mr.mock, "SetCodingSystem", reflect.TypeOf((*MockReader)(nil).SetCodingSystem), cs)
 }
+
+// ByteOrder indicates an expected call of GetByteOrder
+func (mr *MockReaderMockRecorder) ByteOrder() *gomock.Call {
+	mr.mock.ctrl.T.Helper()
+	return mr.mock.ctrl.RecordCallWithMethodType(mr.mock, "ByteOrder", reflect.TypeOf((*MockReader)(nil).ByteOrder))
+}
+
+// ByteOrder mocks base method
+func (m *MockReader) ByteOrder() binary.ByteOrder {
+	m.ctrl.T.Helper()
+	ret := m.ctrl.Call(m, "ByteOrder")
+	ret0, _ := ret[0].(binary.ByteOrder)
+	return ret0
+}
diff --git a/pkg/dicomio/reader.go b/pkg/dicomio/reader.go
index 29af4ee0..4e6064a0 100644
--- a/pkg/dicomio/reader.go
+++ b/pkg/dicomio/reader.go
@@ -67,6 +67,7 @@ type Reader interface {
 	// SetCodingSystem sets the charset.CodingSystem to be used when ReadString
 	// is called.
 	SetCodingSystem(cs charset.CodingSystem)
+	ByteOrder() binary.ByteOrder
 }
 
 type reader struct {
@@ -234,3 +235,7 @@ func (r *reader) SetCodingSystem(cs charset.CodingSystem) {
 func (r *reader) Peek(n int) ([]byte, error) {
 	return r.in.Peek(n)
 }
+
+func (r *reader) ByteOrder() binary.ByteOrder {
+	return r.bo
+}
diff --git a/read.go b/read.go
index 14e7fbf0..b9958e21 100644
--- a/read.go
+++ b/read.go
@@ -212,6 +212,9 @@ func readNativeFrames(d dicomio.Reader, parsedData *Dataset, fc chan<- *frame.Fr
 
 	// Parse the pixels:
 	image.Frames = make([]frame.Frame, nFrames)
+	bo := d.ByteOrder()
+	bytesAllocated := bitsAllocated / 8
+	pixelBuf := make([]byte, bytesAllocated)
 	for frameIdx := 0; frameIdx < nFrames; frameIdx++ {
 		// Init current frame
 		currentFrame := frame.Frame{
@@ -226,24 +229,18 @@ func readNativeFrames(d dicomio.Reader, parsedData *Dataset, fc chan<- *frame.Fr
 		buf := make([]int, int(pixelsPerFrame)*samplesPerPixel)
 		for pixel := 0; pixel < int(pixelsPerFrame); pixel++ {
 			for value := 0; value < samplesPerPixel; value++ {
+				_, err := io.ReadFull(d, pixelBuf)
+				if err != nil {
+					return nil, bytesRead,
+						fmt.Errorf("could not read uint%d from input: %w", bitsAllocated, err)
+				}
+
 				if bitsAllocated == 8 {
-					val, err := d.ReadUInt8()
-					if err != nil {
-						return nil, bytesRead, err
-					}
-					buf[(pixel*samplesPerPixel)+value] = int(val)
+					buf[(pixel*samplesPerPixel)+value] = int(pixelBuf[0])
 				} else if bitsAllocated == 16 {
-					val, err := d.ReadUInt16()
-					if err != nil {
-						return nil, bytesRead, err
-					}
-					buf[(pixel*samplesPerPixel)+value] = int(val)
+					buf[(pixel*samplesPerPixel)+value] = int(bo.Uint16(pixelBuf))
 				} else if bitsAllocated == 32 {
-					val, err := d.ReadUInt32()
-					if err != nil {
-						return nil, bytesRead, err
-					}
-					buf[(pixel*samplesPerPixel)+value] = int(val)
+					buf[(pixel*samplesPerPixel)+value] = int(bo.Uint32(pixelBuf))
 				}
 			}
 			currentFrame.NativeData.Data[pixel] = buf[pixel*samplesPerPixel : (pixel+1)*samplesPerPixel]
@@ -254,7 +251,7 @@ func readNativeFrames(d dicomio.Reader, parsedData *Dataset, fc chan<- *frame.Fr
 		}
 	}
 
-	bytesRead = (bitsAllocated / 8) * samplesPerPixel * pixelsPerFrame * nFrames
+	bytesRead = bytesAllocated * samplesPerPixel * pixelsPerFrame * nFrames
 
 	return &image, bytesRead, nil
 }
diff --git a/read_test.go b/read_test.go
index 8cba5b3d..34912731 100644
--- a/read_test.go
+++ b/read_test.go
@@ -4,7 +4,9 @@ import (
 	"bufio"
 	"bytes"
 	"encoding/binary"
+	"errors"
 	"fmt"
+	"io"
 	"math/rand"
 	"strconv"
 	"testing"
@@ -249,6 +251,19 @@ func TestReadNativeFrames(t *testing.T) {
 			},
 			expectedError: nil,
 		},
+		{
+			Name: "insufficient bytes, uint32",
+			existingData: Dataset{Elements: []*Element{
+				mustNewElement(tag.Rows, []int{2}),
+				mustNewElement(tag.Columns, []int{2}),
+				mustNewElement(tag.NumberOfFrames, []string{"2"}),
+				mustNewElement(tag.BitsAllocated, []int{32}),
+				mustNewElement(tag.SamplesPerPixel, []int{2}),
+			}},
+			data:              []uint16{1, 2, 3, 2, 1, 2, 3, 2, 1, 2, 3, 2, 1, 2, 3},
+			expectedPixelData: nil,
+			expectedError:     io.ErrUnexpectedEOF,
+		},
 		{
 			Name: "missing Columns",
 			existingData: Dataset{Elements: []*Element{
@@ -278,7 +293,7 @@ func TestReadNativeFrames(t *testing.T) {
 			}
 
 			pixelData, _, err := readNativeFrames(r, &tc.existingData, nil)
-			if err != tc.expectedError {
+			if !errors.Is(err, tc.expectedError) {
 				t.Errorf("TestReadNativeFrames(%v): did not get expected error. got: %v, want: %v", tc.data, err, tc.expectedError)
 			}