diff --git a/packages/compiler-sfc/__tests__/compileScript/__snapshots__/defineEmits.spec.ts.snap b/packages/compiler-sfc/__tests__/compileScript/__snapshots__/defineEmits.spec.ts.snap
index a25a384a979..1f59b8c936a 100644
--- a/packages/compiler-sfc/__tests__/compileScript/__snapshots__/defineEmits.spec.ts.snap
+++ b/packages/compiler-sfc/__tests__/compileScript/__snapshots__/defineEmits.spec.ts.snap
@@ -15,6 +15,21 @@ return { myEmit }
 }"
 `;
 
+exports[`defineEmits > nested call expression 1`] = `
+"
+export default {
+  emits: ['foo', 'bar'],
+  setup(__props, { expose: __expose, emit: __emit }) {
+  __expose();
+
+    const transformed = transform(__emit);
+    
+return { transformed }
+}
+
+}"
+`;
+
 exports[`defineEmits > w/ runtime options 1`] = `
 "import { defineComponent as _defineComponent } from 'vue'
 
diff --git a/packages/compiler-sfc/__tests__/compileScript/defineEmits.spec.ts b/packages/compiler-sfc/__tests__/compileScript/defineEmits.spec.ts
index 99cb78a594a..15aa63d9e90 100644
--- a/packages/compiler-sfc/__tests__/compileScript/defineEmits.spec.ts
+++ b/packages/compiler-sfc/__tests__/compileScript/defineEmits.spec.ts
@@ -210,6 +210,23 @@ const emit = defineEmits(['a', 'b'])
     assertCode(content)
   })
 
+  test('nested call expression', () => {
+    const { content } = compile(`
+    <script setup>
+    const transformed = transform(defineEmits(['foo', 'bar']));
+    </script>
+    `)
+
+    // should remove defineEmits import and call
+    expect(content).not.toMatch('defineEmits')
+
+    assertCode(content)
+    expect(content).toMatch(`const transformed = transform(__emit);`)
+    expect(content).toMatch(
+      `setup(__props, { expose: __expose, emit: __emit })`,
+    )
+  })
+
   describe('errors', () => {
     test('w/ both type and non-type args', () => {
       expect(() => {
diff --git a/packages/compiler-sfc/__tests__/compileStyle.spec.ts b/packages/compiler-sfc/__tests__/compileStyle.spec.ts
index b76414364dc..78fd52425e8 100644
--- a/packages/compiler-sfc/__tests__/compileStyle.spec.ts
+++ b/packages/compiler-sfc/__tests__/compileStyle.spec.ts
@@ -211,38 +211,42 @@ color: red
     expect(
       compileScoped(`.div { color: red; } .div:where(:hover) { color: blue; }`),
     ).toMatchInlineSnapshot(`
-    ".div[data-v-test] { color: red;
-    }
-    .div[data-v-test]:where(:hover) { color: blue;
-    }"`)
+      ".div[data-v-test] { color: red;
+      }
+      .div[data-v-test]:where(:hover) { color: blue;
+      }"
+    `)
 
     expect(
       compileScoped(`.div { color: red; } .div:is(:hover) { color: blue; }`),
     ).toMatchInlineSnapshot(`
-    ".div[data-v-test] { color: red;
-    }
-    .div[data-v-test]:is(:hover) { color: blue;
-    }"`)
+      ".div[data-v-test] { color: red;
+      }
+      .div[data-v-test]:is(:hover) { color: blue;
+      }"
+    `)
 
     expect(
       compileScoped(
         `.div { color: red; } .div:where(.foo:hover) { color: blue; }`,
       ),
     ).toMatchInlineSnapshot(`
-    ".div[data-v-test] { color: red;
-    }
-    .div[data-v-test]:where(.foo:hover) { color: blue;
-    }"`)
+      ".div[data-v-test] { color: red;
+      }
+      .div[data-v-test]:where(.foo:hover) { color: blue;
+      }"
+    `)
 
     expect(
       compileScoped(
         `.div { color: red; } .div:is(.foo:hover) { color: blue; }`,
       ),
     ).toMatchInlineSnapshot(`
-    ".div[data-v-test] { color: red;
-    }
-    .div[data-v-test]:is(.foo:hover) { color: blue;
-    }"`)
+      ".div[data-v-test] { color: red;
+      }
+      .div[data-v-test]:is(.foo:hover) { color: blue;
+      }"
+    `)
   })
 
   test('media query', () => {
diff --git a/packages/compiler-sfc/src/compileScript.ts b/packages/compiler-sfc/src/compileScript.ts
index 962b7bc7936..6c8810a6367 100644
--- a/packages/compiler-sfc/src/compileScript.ts
+++ b/packages/compiler-sfc/src/compileScript.ts
@@ -46,6 +46,8 @@ import {
   DEFINE_EMITS,
   genRuntimeEmits,
   processDefineEmits,
+  processNestedDefineEmits,
+  replaceDefineEmits,
 } from './script/defineEmits'
 import { DEFINE_EXPOSE, processDefineExpose } from './script/defineExpose'
 import { DEFINE_OPTIONS, processDefineOptions } from './script/defineOptions'
@@ -544,7 +546,7 @@ export function compileScript(
 
           // defineEmits
           const isDefineEmits =
-            !isDefineProps && processDefineEmits(ctx, init, decl.id)
+            !isDefineProps && processNestedDefineEmits(ctx, init, decl.id)
           !isDefineEmits &&
             (processDefineSlots(ctx, init, decl.id) ||
               processDefineModel(ctx, init, decl.id))
@@ -572,11 +574,7 @@ export function compileScript(
               left--
             }
           } else if (isDefineEmits) {
-            ctx.s.overwrite(
-              startOffset + init.start!,
-              startOffset + init.end!,
-              '__emit',
-            )
+            replaceDefineEmits(ctx, init)
           } else {
             lastNonRemoved = i
           }
diff --git a/packages/compiler-sfc/src/script/defineEmits.ts b/packages/compiler-sfc/src/script/defineEmits.ts
index e4e6bdabf36..2017a1f94ad 100644
--- a/packages/compiler-sfc/src/script/defineEmits.ts
+++ b/packages/compiler-sfc/src/script/defineEmits.ts
@@ -16,6 +16,36 @@ import {
 
 export const DEFINE_EMITS = 'defineEmits'
 
+/**
+ * Detects if this node recursively contains a call to `defineEmits()`.
+ *
+ * @returns true If the given node itself is a call to `defineEmits()` and should be removed, false otherwise.
+ */
+export function processNestedDefineEmits(
+  ctx: ScriptCompileContext,
+  node: Node,
+  declId?: LVal,
+): boolean {
+  if (node.type !== 'CallExpression') {
+    return false
+  }
+  if (processDefineEmits(ctx, node, declId)) {
+    return true
+  }
+  for (const arg of node.arguments) {
+    if (processNestedDefineEmits(ctx, arg, declId)) {
+      replaceDefineEmits(ctx, arg)
+    }
+  }
+
+  return false
+}
+
+/**
+ * Detects if the node is a call to `defineEmits()`.
+ *
+ * @returns true If the given node itself is a call to `defineEmits()` and should be removed, false otherwise.
+ */
 export function processDefineEmits(
   ctx: ScriptCompileContext,
   node: Node,
@@ -45,6 +75,17 @@ export function processDefineEmits(
   return true
 }
 
+export function replaceDefineEmits(
+  ctx: ScriptCompileContext,
+  node: Node,
+): void {
+  ctx.s.overwrite(
+    ctx.startOffset! + node.start!,
+    ctx.startOffset! + node.end!,
+    '__emit',
+  )
+}
+
 export function genRuntimeEmits(ctx: ScriptCompileContext): string | undefined {
   let emitsDecl = ''
   if (ctx.emitsRuntimeDecl) {