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#61: Bodybuilding and Steroids | Progesterone for Men? | Basic Bioenergetic Therapies with Ray Peat [3fVx5yk73t4].vtt
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WEBVTT
00:00:00.000 --> 00:00:16.160
Okay, and we're live, Georgie DeKalb, Ray Peat.
00:00:16.160 --> 00:00:18.940
Guys, thank you so much for joining us today.
00:00:18.940 --> 00:00:19.940
Thank you, Georgie.
00:00:19.940 --> 00:00:20.940
Thank you, Ray.
00:00:20.940 --> 00:00:24.520
And we're just going to rifle through a bunch of questions, but before we do that, how are
00:00:24.520 --> 00:00:25.520
you, Ray?
00:00:25.520 --> 00:00:26.520
Very good.
00:00:26.520 --> 00:00:27.520
Yeah?
00:00:27.520 --> 00:00:32.120
So the weather had gotten a little bit sunnier in Eugene, so that's always a positive.
00:00:32.120 --> 00:00:35.520
It's going to be in the hundreds, over a hundred this weekend.
00:00:35.520 --> 00:00:39.120
And then how do you, do you go sit in the sun or what do you do?
00:00:39.120 --> 00:00:43.800
No, I'm going to stay inside all day, tomorrow at least.
00:00:43.800 --> 00:00:49.680
We open the door at about 1 a.m. when it cools off, blow in some cooler air and then close
00:00:49.680 --> 00:00:51.200
it up for the day.
00:00:51.200 --> 00:00:55.520
The house is concrete, so it holds its temperature for about a day.
00:00:55.520 --> 00:00:57.400
And blocking that 5G as well.
00:00:57.400 --> 00:00:59.320
Yeah, yeah, a little bit.
00:00:59.320 --> 00:01:00.880
Okay, and then Georgie, how are you, sir?
00:01:00.880 --> 00:01:04.160
I really like your elevator music that you put at the start of the show.
00:01:04.160 --> 00:01:05.160
It was very soothing.
00:01:05.160 --> 00:01:07.000
Did you hear it through my headphones?
00:01:07.000 --> 00:01:09.600
No, I heard the music.
00:01:09.600 --> 00:01:11.000
Was I not supposed to hear it?
00:01:11.000 --> 00:01:12.000
Oh, no, you weren't.
00:01:12.000 --> 00:01:13.000
Okay, that's a little bit weird.
00:01:13.000 --> 00:01:14.440
Ray, did you hear the music too?
00:01:14.440 --> 00:01:15.440
Yeah.
00:01:15.440 --> 00:01:16.440
Oh, okay, weird.
00:01:16.440 --> 00:01:17.440
Okay, that's a new...
00:01:17.440 --> 00:01:18.440
I thought it was kind of interesting.
00:01:18.440 --> 00:01:22.240
You tried to hold a conversation over this really loud music and I thought, "Wow, that
00:01:22.240 --> 00:01:23.240
must be a new feature."
00:01:23.240 --> 00:01:24.240
That's one of the...
00:01:24.240 --> 00:01:26.280
In conference call music.
00:01:26.280 --> 00:01:28.920
That's one of the reasons we're upgrading equipment, because when I'm talking to you
00:01:28.920 --> 00:01:32.400
guys before the show, I'm always hearing music and it's obnoxious.
00:01:32.400 --> 00:01:33.880
Okay, enough of that.
00:01:33.880 --> 00:01:37.960
This show, like I said, told you guys before, I don't feel like it's for me or necessarily
00:01:37.960 --> 00:01:42.560
per se Georgie, although Ray and Georgie, you guys' interfacing and bouncing ideas off
00:01:42.560 --> 00:01:45.400
each other is, I think, what the people are here to listen to.
00:01:45.400 --> 00:01:49.360
Okay, so I'm just going to go through these questions and read them.
00:01:49.360 --> 00:01:53.400
And Ray, some of this stuff is going to be redundant and answer as much or as little
00:01:53.400 --> 00:01:55.000
as you want for all of this.
00:01:55.000 --> 00:02:02.880
So our first one is from Drew F. and he says, "Trestosterone/MENT is not 5-alpha reduced,
00:02:02.880 --> 00:02:07.920
but bodybuilders and some post-finasteride sufferers experience benefits in terms of
00:02:07.920 --> 00:02:09.840
mood, anabolism, et cetera.
00:02:09.840 --> 00:02:14.240
Is androgen receptor agonism a likely explanation for the effects?
00:02:14.240 --> 00:02:17.320
It is a much stronger androgen than testosterone."
00:02:17.320 --> 00:02:20.040
Which reduced testosterone is it?
00:02:20.040 --> 00:02:21.040
Georgie, do you know what this is?
00:02:21.040 --> 00:02:22.040
It's...
00:02:22.040 --> 00:02:23.040
Yes, I know.
00:02:23.040 --> 00:02:24.440
It's a new steroid.
00:02:24.440 --> 00:02:31.640
It's 7-alpha-methylated version of nendrolone, which is a carbon-18 steroid of the estrein
00:02:31.640 --> 00:02:32.640
family.
00:02:32.640 --> 00:02:33.640
So it was...
00:02:33.640 --> 00:02:36.040
I was always suspicious when they add the methyl group.
00:02:36.040 --> 00:02:38.360
Yeah, it's actually very hepatotoxic.
00:02:38.360 --> 00:02:45.160
As you know, Ray, methyl groups at position 17, 7, and potentially others, they've all
00:02:45.160 --> 00:02:48.440
been proven to have severe hepatotoxicity.
00:02:48.440 --> 00:02:53.400
But bodybuilders like it because I guess they don't value their liver that much, but also
00:02:53.400 --> 00:02:58.600
it's the steroid that can achieve the same with lower doses and they think it's worth
00:02:58.600 --> 00:03:01.960
it instead of abusing the testosterone in higher dosages.
00:03:01.960 --> 00:03:07.440
That steroid was developed as a male contraceptive candidate, and I think it's still in clinical
00:03:07.440 --> 00:03:08.560
trials for that.
00:03:08.560 --> 00:03:13.160
But even the company that developed it and is running the clinical trials got discouraged
00:03:13.160 --> 00:03:14.160
given the hepatotoxicity.
00:03:14.160 --> 00:03:17.040
Ray, do you want to clarify the methyl group?
00:03:17.040 --> 00:03:20.280
So adding a methyl group to a steroid is risky, you said?
00:03:20.280 --> 00:03:24.640
Yeah, it just sends it off on unknown pathways.
00:03:24.640 --> 00:03:31.080
The liver never had to deal with such things, and so I think it's extremely unpredictable
00:03:31.080 --> 00:03:32.080
and dangerous.
00:03:32.080 --> 00:03:33.080
Good stuff.
00:03:33.080 --> 00:03:35.920
And then we've talked about post-finasteride a bunch, so I want to kind of get into that
00:03:35.920 --> 00:03:36.920
again.
00:03:36.920 --> 00:03:37.920
I kind of want to...
00:03:37.920 --> 00:03:46.080
I think his main question was, "Is activation of the androgen receptor a plausible explanation
00:03:46.080 --> 00:03:54.280
of the antidepressant and general feelings of well-being from using these androgenic
00:03:54.280 --> 00:03:55.280
steroids?"
00:03:55.280 --> 00:03:56.280
I think it's plausible.
00:03:56.280 --> 00:03:57.280
Great stuff.
00:03:57.280 --> 00:03:58.280
Thank you for that, guys.
00:03:58.280 --> 00:03:59.280
Okay, Marcelo, this is just kind of a statement.
00:03:59.280 --> 00:04:01.000
Thank you, Danny, for your contributions to the community.
00:04:01.000 --> 00:04:02.400
You are a big reason why Ray's work...
00:04:02.400 --> 00:04:03.800
Wealth of knowledge is available to us.
00:04:03.800 --> 00:04:07.440
Thank you so much, Georgie, for his continuing curiosity and dedicating his life's work towards
00:04:07.440 --> 00:04:08.840
advancements in this space.
00:04:08.840 --> 00:04:09.840
Hope this helps.
00:04:09.840 --> 00:04:10.840
Thank you, Marcelo.
00:04:10.840 --> 00:04:11.840
Sincerely appreciate that.
00:04:11.840 --> 00:04:15.560
Thank you to Ray for being humble and inspiration for all things.
00:04:15.560 --> 00:04:20.200
Andrew Wallace says, "What would you do if you had Crohn's?
00:04:20.200 --> 00:04:21.680
What would be your protocol?"
00:04:21.680 --> 00:04:22.680
Me?
00:04:22.680 --> 00:04:25.680
Yeah, Ray, I always assume...
00:04:25.680 --> 00:04:28.920
I guess I'm just asking you, and then Georgi can chime in at any point.
00:04:28.920 --> 00:04:32.040
Pretty much what I do anyway.
00:04:32.040 --> 00:04:39.280
Assume that the intestine is my contact with the world, and I have to protect it, and so
00:04:39.280 --> 00:04:47.160
I don't want to offend it in any way, and Crohn's disease is a seriously offended intestine.
00:04:47.160 --> 00:04:51.660
And from what I've read, it seems like you've dealt with a lot of serious intestinal things
00:04:51.660 --> 00:04:54.080
over the years, as one would in this environment.
00:04:54.080 --> 00:04:56.760
And so it's not like you're speaking from reading...
00:04:56.760 --> 00:05:00.200
I know you read, obviously, a lot, but you're speaking from personal experience.
00:05:00.200 --> 00:05:01.200
Is that right?
00:05:01.200 --> 00:05:02.200
Yeah.
00:05:02.200 --> 00:05:09.560
Starting as a baby with migraines, which recurred every time I would do certain things
00:05:09.560 --> 00:05:13.760
wrong up until my mid-40s.
00:05:13.760 --> 00:05:14.760
I would still...
00:05:14.760 --> 00:05:21.520
The last one, for example, was when I was visiting in San Francisco and didn't realize
00:05:21.520 --> 00:05:27.960
that they had fluoridated water, and I would occasionally drink some of that water, and
00:05:27.960 --> 00:05:36.240
I was taking Cynoplus or Cynomel orally, and within two or three days, I had a tremendous
00:05:36.240 --> 00:05:44.440
migraine, and that started me thinking about it, and fluoride can totally wipe out the
00:05:44.440 --> 00:05:53.760
activity of T3 if it happens to be present in your stomach and the T3 is exposed to it.
00:05:53.760 --> 00:05:54.760
Amazing stuff.
00:05:54.760 --> 00:05:55.760
Okay, so obviously...
00:05:55.760 --> 00:05:57.720
I have a question in regards to Crohn's disease.
00:05:57.720 --> 00:06:02.160
Ray, have you seen some of the more recent studies claiming that Crohn's disease may
00:06:02.160 --> 00:06:08.120
be caused by a type of mycobacteria, which is known to cause Crohn's disease in animals,
00:06:08.120 --> 00:06:11.080
and now they're saying the same thing may be true in humans?
00:06:11.080 --> 00:06:18.760
Yeah, but the inflammation and poor digestion are set up to conditions for such things to
00:06:18.760 --> 00:06:20.600
accumulate and multiply.
00:06:20.600 --> 00:06:26.640
So basically making sure that you don't irritate your intestine more than absolutely necessary
00:06:26.640 --> 00:06:30.520
is at the basis of a protocol for keeping...
00:06:30.520 --> 00:06:34.680
You can find a mycoplasm in just about any sick person.
00:06:34.680 --> 00:06:38.420
It's sort of opportunistic and looks for a sort of place to live.
00:06:38.420 --> 00:06:44.920
So maybe this antibiotic therapy that they're now trying in Europe for this potentially...
00:06:44.920 --> 00:06:48.400
They're treating it as a bacteria infection, but it's really destroying the microbiome
00:06:48.400 --> 00:06:51.960
and keeping the intestine sterile, which reduces the inflammation.
00:06:51.960 --> 00:06:52.960
Not necessarily...
00:06:52.960 --> 00:06:54.200
It's not only one bacteria, it's just...
00:06:54.200 --> 00:06:59.160
This is helping because it's reducing the amount of bacteria in the intestine anyways.
00:06:59.160 --> 00:07:06.920
Yeah, just taking a series of penicillin doses or eating raw carrots, for example, can have
00:07:06.920 --> 00:07:08.760
very similar effects.
00:07:08.760 --> 00:07:16.440
And in both rats and people, it turns out that anything that cleans up your intestine
00:07:16.440 --> 00:07:22.880
will lower your cortisol and estrogen and increase your progesterone just because the
00:07:22.880 --> 00:07:28.840
intestine is such a chronic drain and source of stress.
00:07:28.840 --> 00:07:33.600
In regards to the carrot salad and in general fiber, what are your thoughts on supplementing
00:07:33.600 --> 00:07:36.800
with pure cellulose if one could find a pure source?
00:07:36.800 --> 00:07:37.800
It would be interesting.
00:07:37.800 --> 00:07:43.600
They used to sell basically a cellulose tablet for weight loss.
00:07:43.600 --> 00:07:49.080
I've never tried one, but it seemed like a good idea because cellulose doesn't have the
00:07:49.080 --> 00:07:53.200
estrogen-promoting symptoms that a lot of other fibers do.
00:07:53.200 --> 00:07:55.880
Yeah, the reason I'm mentioning is I was reading some studies.
00:07:55.880 --> 00:08:00.600
They're using various cellulose esters as binders for drugs for developing pharmaceutical
00:08:00.600 --> 00:08:06.200
drugs and some of these esters, like for example, ethyl cellulose, showed remarkable antibacterial
00:08:06.200 --> 00:08:08.640
effects in animals and reduced inflammation.
00:08:08.640 --> 00:08:11.880
So I thought maybe it's because it's clearing out their intestines somehow.
00:08:11.880 --> 00:08:12.880
Oh, yeah.
00:08:12.880 --> 00:08:17.680
It was a very popular laxative effect as well as weight loss.
00:08:17.680 --> 00:08:20.360
Was this in the past, like in the maybe '60s or '70s?
00:08:20.360 --> 00:08:26.200
I used to see the ads for it on TV as recently as 1986, I think it was.
00:08:26.200 --> 00:08:27.200
Interesting, very interesting.
00:08:27.200 --> 00:08:32.000
Speaking of cortisol, okay, this one's from New Health and they say good cortisol blocker
00:08:32.000 --> 00:08:33.680
supplements for weight loss.
00:08:33.680 --> 00:08:35.000
What is your thoughts on that, Ray?
00:08:35.000 --> 00:08:36.000
What blocker?
00:08:36.000 --> 00:08:37.680
Like a cortisol blocker.
00:08:37.680 --> 00:08:44.480
Progesterone and pregnenolone are the best ones I know of, but working at the pituitary
00:08:44.480 --> 00:08:55.160
level, a lot of things, sugar, aspirin, probably sodium, anything that stabilizes your blood
00:08:55.160 --> 00:09:01.160
sugar and metabolism, reduces inflammation, will defend you against cortisol.
00:09:01.160 --> 00:09:02.160
Thanks for that.
00:09:02.160 --> 00:09:06.200
New Health says, "There's now a spinoff of the Ray Peat community with Morley Robbins
00:09:06.200 --> 00:09:08.880
ideas, aka Ceruloplasmin.
00:09:08.880 --> 00:09:12.440
Would you be willing to do a show on this from a Ray Peat perspective?"
00:09:12.440 --> 00:09:16.520
I think these were when they originally thought that Georgie and I were just going to do a
00:09:16.520 --> 00:09:17.520
Q&A.
00:09:17.520 --> 00:09:19.640
Ray, what are your thoughts on Ceruloplasmin?
00:09:19.640 --> 00:09:23.400
It's an acute phase reactant, so do you want to be increasing Ceruloplasmin?
00:09:23.400 --> 00:09:26.960
Is that a goal of a diet or lifestyle or supplement routine?
00:09:26.960 --> 00:09:30.720
Not my goal.
00:09:30.720 --> 00:09:32.240
Do you want to comment on Morley Robbins?
00:09:32.240 --> 00:09:33.240
You know who that is?
00:09:33.240 --> 00:09:34.240
Are you familiar with their work?
00:09:34.240 --> 00:09:35.240
No, no.
00:09:35.240 --> 00:09:36.240
I have a question.
00:09:36.240 --> 00:09:41.120
If somebody has low Ceruloplasmin, some of the studies claim that this is a sign of low
00:09:41.120 --> 00:09:42.120
thyroid function.
00:09:42.120 --> 00:09:46.120
In a situation like that, considering that Ceruloplasmin apparently takes care of the
00:09:46.120 --> 00:09:51.440
copper and makes sure it doesn't become toxic to the various organs, would somebody be potentially
00:09:51.440 --> 00:09:54.960
at risk if they have low Ceruloplasmin and low thyroid?
00:09:54.960 --> 00:09:59.120
Would they be at risk when eating high copper foods like liver and shellfish?
00:09:59.120 --> 00:10:01.320
I think so.
00:10:01.320 --> 00:10:07.640
Did you ever read Carl Pfeiffer's books?
00:10:07.640 --> 00:10:13.680
I think he caused himself to lose pigment by being so obsessive about keeping copper
00:10:13.680 --> 00:10:14.680
down.
00:10:14.680 --> 00:10:21.520
He was very concentrated on the risk of too much copper, probably having seen some people
00:10:21.520 --> 00:10:24.120
with Ceruloplasmin deficiency.
00:10:24.120 --> 00:10:31.200
Ann Louise Gittleman, Andy Cutler, and Carl Pfeiffer were all about copper toxicity.
00:10:31.200 --> 00:10:38.200
It seems like from reading your work that they were misled in what they thought was
00:10:38.200 --> 00:10:39.200
going on.
00:10:39.200 --> 00:10:40.200
Yeah.
00:10:40.200 --> 00:10:44.200
He took a little capsule of flowers of sulfur every day for many, many years.
00:10:44.200 --> 00:10:47.520
He had no trace of skin or hair pigment left.
00:10:47.520 --> 00:10:48.520
Okay, great stuff.
00:10:48.520 --> 00:10:50.320
This one's from Joseph.
00:10:50.320 --> 00:10:54.320
He says, "Can you speak about nitric oxide and the word on the street that it's good
00:10:54.320 --> 00:10:58.360
for Cialis or Viagra, so that it works like those substances?"
00:10:58.360 --> 00:11:04.680
I'm afraid there is quite a bit of overlap.
00:11:04.680 --> 00:11:12.920
The initial, as soon as nitric oxide was discovered to be produced in the body, they were seeing
00:11:12.920 --> 00:11:17.000
its involvement in everything degenerative and harmful.
00:11:17.000 --> 00:11:25.280
Then when the Viagra came on the market, suddenly for about five or six years, everything published
00:11:25.280 --> 00:11:31.120
was how great nitric oxide is, it prevents hypertension and protects you against everything.
00:11:31.120 --> 00:11:38.520
Thousands of articles came out suddenly reversing it from a dangerous free radical to a cure-all.
00:11:38.520 --> 00:11:47.200
Then about 10 or 15 years ago, there was a gradual return to sanity and realizing that
00:11:47.200 --> 00:12:04.120
it's one of the very central things to degeneration, aging, the follow-up of trauma, estrogen interactions,
00:12:04.120 --> 00:12:12.080
everything stress-related and degeneration-related involves the pro-inflammatory effects of ethanol.
00:12:12.080 --> 00:12:13.080
Two follow-up questions.
00:12:13.080 --> 00:12:17.760
One says, "Is aspirin safe to take every day and also is lactose-free milk?"
00:12:17.760 --> 00:12:24.800
It doesn't taste very good, but I think it's safe enough.
00:12:24.800 --> 00:12:33.880
It probably doesn't let you absorb nutrients quite as well as natural lactose-containing
00:12:33.880 --> 00:12:36.680
milk, but I don't think it's harmful.
00:12:36.680 --> 00:12:39.440
Then your thoughts on using aspirin every day?
00:12:39.440 --> 00:12:48.160
Yeah, when I had a good supply, I was taking it every day very consistently, but sometimes
00:12:48.160 --> 00:12:55.680
I forget to take it when it isn't in a convenient form, like some of it is powdered so fine
00:12:55.680 --> 00:13:01.520
it's choking when you try to take it just on your tongue.
00:13:01.520 --> 00:13:02.720
Georgie, interrupt me at any time.
00:13:02.720 --> 00:13:05.000
Okay, this one's a little bit long, so bear with me for a second.
00:13:05.000 --> 00:13:09.000
"I've been trying to have a baby for more than a year, but I have azuspermia.
00:13:09.000 --> 00:13:13.960
Found after three semen analyses and undetectable levels of spurn after a testicular ultrasound,
00:13:13.960 --> 00:13:20.120
they found a small varicocele in both testicles.
00:13:20.120 --> 00:13:23.880
I've been taking seven to eight milligrams of extremistain for three weeks.
00:13:23.880 --> 00:13:27.120
For how much longer is it safe to take?"
00:13:27.120 --> 00:13:28.360
So this is the first question.
00:13:28.360 --> 00:13:33.800
"Will continued extremistain use help me fix the varicocele as well as the azus-"
00:13:33.800 --> 00:13:34.800
What's she taking?
00:13:34.800 --> 00:13:35.800
Exemistain.
00:13:35.800 --> 00:13:37.600
It's a steroidal aromatase inhibitor.
00:13:37.600 --> 00:13:39.520
I'll just finish up this question.
00:13:39.520 --> 00:13:42.240
It's like there's two more sentences here and we can go through it.
00:13:42.240 --> 00:13:45.920
"If exemistain doesn't fix the azuspermia, what else can I do?
00:13:45.920 --> 00:13:51.280
I'd like to avoid having a varicocele ectomy or even worse, surgical sperm extraction from
00:13:51.280 --> 00:13:52.440
IVF.
00:13:52.440 --> 00:13:57.120
After three weeks of exemistain, my total testosterone went from 400 to 756.
00:13:57.120 --> 00:14:01.080
Exemistain has also increased my FSH and LH and are now above standard range.
00:14:01.080 --> 00:14:04.240
I thought FSH and LH would go down as testosterone goes up."
00:14:04.240 --> 00:14:08.120
So were there bits of that question that you have comments on, Rick?
00:14:08.120 --> 00:14:17.760
Yeah, I think you can get a safer inhibition of aromatase using aspirin, progesterone,
00:14:17.760 --> 00:14:19.720
completely safe things.
00:14:19.720 --> 00:14:27.440
Thyroid is very important, but just with aspirin, progesterone, and thyroid, you can get your
00:14:27.440 --> 00:14:34.680
ratio back, testosterone, pregnenolone up and estrogen down.
00:14:34.680 --> 00:14:43.440
Supplementing pregnenolone and thyroxine historically was very effective for correcting infertility
00:14:43.440 --> 00:14:47.920
and enlivening inactive sperms.
00:14:47.920 --> 00:14:51.960
And so the azuspermia, if the cholesterol is high and the person wasn't taking enough
00:14:51.960 --> 00:14:55.520
thyroid, that would be a result of that with high estrogen?
00:14:55.520 --> 00:15:04.640
Yeah, the thyroid and pregnenolone make their energy-producing system revive.
00:15:04.640 --> 00:15:05.640
Great stuff, thanks for that.
00:15:05.640 --> 00:15:08.440
Okay, Peggy says, "Question for the Q&A.
00:15:08.440 --> 00:15:15.520
Thoughts on ivermectin for COVID, prophylaxis, and any alternative as it is almost impossible
00:15:15.520 --> 00:15:17.280
to get a prescription for it.
00:15:17.280 --> 00:15:18.280
Thank you."
00:15:18.280 --> 00:15:24.320
Prophylaxis suggests you would be taking some every day for an indefinite time until you
00:15:24.320 --> 00:15:34.520
didn't get the infection, and the normal use of it is a very short course.
00:15:34.520 --> 00:15:41.760
About one person in a thousand in the studies of using it to treat parasites will show signs
00:15:41.760 --> 00:15:42.760
of brain damage.
00:15:42.760 --> 00:15:50.200
I don't think it's a good idea to take maybe thousands of daily doses, even a moderate
00:15:50.200 --> 00:15:54.160
amount of something that once in a while is known to cause brain damage.
00:15:54.160 --> 00:15:58.200
There was some podcast that was talking about ivermectin and a bunch of people emailed me
00:15:58.200 --> 00:15:59.920
about it the exact same time.
00:15:59.920 --> 00:16:01.640
Again, Georgie, interrupt at any time.
00:16:01.640 --> 00:16:03.160
Okay, so this person says-
00:16:03.160 --> 00:16:07.680
I can give a few more, I mean, based on the studies that recently came out.
00:16:07.680 --> 00:16:11.960
Methylene blue, a well-known antiviral, at least four studies came out in the last month
00:16:11.960 --> 00:16:14.840
saying it can both prevent and treat COVID-19.
00:16:14.840 --> 00:16:18.840
Of course, there's no medical advice, but that's what the study said.
00:16:18.840 --> 00:16:22.920
Another hydroxychloroquine, you can try plain old quinine.
00:16:22.920 --> 00:16:27.600
My personal favorite, hydroxychloroquine is just a patented, more liver-toxic version
00:16:27.600 --> 00:16:28.600
of quinine.
00:16:28.600 --> 00:16:30.920
Naringenin, also a few good studies.
00:16:30.920 --> 00:16:36.920
So drinking orange juice should have similar effect than taking the isolated version.
00:16:36.920 --> 00:16:42.520
And aspirin, vitamin C and vitamin D, I mean, all of these now have quite a few studies
00:16:42.520 --> 00:16:43.520
behind them.
00:16:43.520 --> 00:16:46.800
Unfortunately, everything is being censored by mainstream media, so you have to go to
00:16:46.800 --> 00:16:47.920
PubMed to find them.
00:16:47.920 --> 00:16:49.920
But I wouldn't say-
00:16:49.920 --> 00:16:54.080
Ivermectin would be one of the last things I would try considering all the other safer
00:16:54.080 --> 00:16:55.720
alternatives that are out there.
00:16:55.720 --> 00:17:00.360
Cyproheptadine, famotidine, which is an acid blocker, but apparently is also a potent anti-serotonin
00:17:00.360 --> 00:17:01.360
agent as well.
00:17:01.360 --> 00:17:05.080
Really, I don't know where the Ivermectin craze is coming from.
00:17:05.080 --> 00:17:11.160
Maybe that's the only thing that hit the mainstream news, but tons of other chemicals, safer and
00:17:11.160 --> 00:17:16.160
cheaper and available over the counter that can do just as well, if not better, than Ivermectin
00:17:16.160 --> 00:17:17.720
with fewer side effects.
00:17:17.720 --> 00:17:21.160
Vitamin D is very effective.
00:17:21.160 --> 00:17:29.400
There was a study done in Spain in a hospital which was withdrawn after a lot of doctors
00:17:29.400 --> 00:17:34.480
wrote ignorant letters to the publisher.
00:17:34.480 --> 00:17:40.480
For some reason, the editor caved in and had it withdrawn.
00:17:40.480 --> 00:17:47.720
But it was very clear that they gave, I think it was 6,000 units, something like that, per
00:17:47.720 --> 00:17:48.720
day.
00:17:48.720 --> 00:17:54.080
Maybe it was 8,000 first dose and then 6,000 units a day to people who were admitted to
00:17:54.080 --> 00:18:00.040
hospital intensive care, very sick with COVID.
00:18:00.040 --> 00:18:07.440
Simply that treatment with vitamin D reduced mortality by about, I think it was 60%, just
00:18:07.440 --> 00:18:14.520
an absolutely clear difference, but the readers who didn't like vitamin D quibbled that they
00:18:14.520 --> 00:18:17.400
hadn't done statistics quite right.
00:18:17.400 --> 00:18:22.560
But you can't miss a 60% disappearance of dead patients.
00:18:22.560 --> 00:18:30.400
I would like to see a doctor argue that 60% more live people is statistically insignificant.
00:18:30.400 --> 00:18:35.360
Very stupid people who are complaining.
00:18:35.360 --> 00:18:39.720
A shout out to the Kate Deering and Kitty Blomfield podcast you did with them.
00:18:39.720 --> 00:18:43.640
I thought it was like a tour de force and you at least, I thought you cleared up every
00:18:43.640 --> 00:18:47.360
single anti-vitamin D argument that exists on the internet right now.
00:18:47.360 --> 00:18:51.560
I was very thankful for that podcast and I think you can type in Kitty Blomfield, a win
00:18:51.560 --> 00:18:56.120
at life podcast, vitamin D, Ray Peat, and a person can find it instantaneously.
00:18:56.120 --> 00:18:57.120
Okay.
00:18:57.120 --> 00:18:58.120
Hi, Danny.
00:18:58.120 --> 00:18:59.120
Hi, Georgie.
00:18:59.120 --> 00:19:00.120
Hi, Ray Peat.
00:19:00.120 --> 00:19:01.120
Many thanks for the show.
00:19:01.120 --> 00:19:02.120
Please keep going.
00:19:02.120 --> 00:19:03.120
I have one question.
00:19:03.120 --> 00:19:06.880
My 10 year old daughter has hypothyroid symptoms, low energy, weight gain, digestive problems.
00:19:06.880 --> 00:19:11.480
Her TSH is between four and five and her free T4 is around 12.
00:19:11.480 --> 00:19:14.400
Doctors here don't test for other markers, unfortunately.
00:19:14.400 --> 00:19:17.800
Doctor says everything is okay and no need to worry.
00:19:17.800 --> 00:19:21.320
Do you have any suggestions what we can do?
00:19:21.320 --> 00:19:23.840
Preferably nutritional plus lifestyle.
00:19:23.840 --> 00:19:24.840
Thanks again, Timo.
00:19:24.840 --> 00:19:25.840
P.S.
00:19:25.840 --> 00:19:28.200
I'm lucky you could take my question.
00:19:28.200 --> 00:19:29.720
What do you think about that?
00:19:29.720 --> 00:19:32.080
Very important to get the TSH down.
00:19:32.080 --> 00:19:40.400
TSH at that level itself is causing symptoms, pro-inflammatory symptoms and it's going to
00:19:40.400 --> 00:19:50.560
disturb her puberty development, all kinds of development and the history of that bizarre
00:19:50.560 --> 00:20:00.680
attitude towards TSH, I think it's on my website, 50 Years of Fraud is part of the title.
00:20:00.680 --> 00:20:08.280
There's just no scientific basis for relying on TSH, especially at such very high levels
00:20:08.280 --> 00:20:09.880
as five.
00:20:09.880 --> 00:20:13.600
And you know, just my limited understanding of things of reading through hypothyroidism,
00:20:13.600 --> 00:20:17.360
the unsuspected illness, like he wrote, it talks about childhood hypothyroidism and it's
00:20:17.360 --> 00:20:21.680
not crazy to investigate a thyroid supplement for a child, right?
00:20:21.680 --> 00:20:23.640
Oh, not at all.
00:20:23.640 --> 00:20:26.920
Sometimes it has started at a very young age.
00:20:26.920 --> 00:20:34.200
It's increasingly important around seven or eight or nine when the first signs of puberty
00:20:34.200 --> 00:20:38.440
are coming on because the estrogen is going to slow down the thyroid function.
00:20:38.440 --> 00:20:39.440
Great stuff.