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kmud-141121-nitric-oxide.vtt
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WEBVTT
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specializing in healthy kitchenware and food preserving supplies like stainless steel dehydrators
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and old world pickling crocks.
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Organic Grace is on the main street in Garberville and is on the web at organicgrace.com.
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And as usual throughout the broadcast day, the views and opinions expressed on Redwood
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Community Radio are those of the speakers and not necessarily those of the listeners,
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sorry, certainly not necessarily those of the listeners, but not necessarily those of
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the station, the underwriters, or the board of directors.
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And it could easily be sarcasm, but of course sarcasm is totally easy to understand on the
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radio, so you would know it if it is.
00:00:41.600 --> 00:00:49.080
And without further ado, we'll get to our next talk show, which is Ask Your Herb Doctor.
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Oops.
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[Music]
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[Applause]
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Well, thank you once again. This is Ask Your Herb Doctor, KMU DeGarboville, 91.1 FM.
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My name's Andrew Murray, and for those of you who perhaps have never listened to the
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show, which runs every third Friday of the month from 7 to 8pm, I'm a licensed medical
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herbalist who trained in England and graduated there with a degree in herbal medicine.
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My wife and I run a clinic in Garboville where we consult with clients about a wide range
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of conditions and recommend herbal medicines and dietary advice, and has become very consistent
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with the last couple of years. Dr. Peat is happily joining us on the show to share his
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latest discoveries in his research. So, you're listening to Ask Your Herb Doctor on KMU DeGarboville,
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91.1 FM, and from 7.30 until the end of the show at 8 o'clock, you're invited to call
00:03:26.080 --> 00:03:33.080
in with any questions either related or unrelated to this month's subject of nitric oxide.
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The number, if you live in the area, is 923 3911, or if you live outside the area, the
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toll-free number is 1800 KMUD RAD, and we can be reached toll-free on 1-888-WBM-HERB
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for consultations or further information Monday through Friday, 9 to 5.
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So, Dr. Peat, thanks so much for joining us again.
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For those, perhaps, people who have never heard you, would you give an outline of your
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academic and professional background so that people can understand the work that you've
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been doing?
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First, I studied for a master's degree at the University of Oregon in literature-related
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things, and then studied linguistics for a while. Finally, came back to study biology,
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1968 to '72, specializing in physiology of reproduction and aging, and especially the
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biochemical side of aging physiology.
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Okay. All right. So, I wanted to ask you some questions about your most recent newsletter,
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which was based on nitric oxide, and hopefully open it up for people to understand the context
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in which we're talking about as a product. I think the very first question that I wanted
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to pose, given that the compound manufactured by Pfizer will be well known to many, both
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in its generic form and in the off-counter or other brand label types of product, being
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Viagra, nitric oxide majorly has a vasodilatory effect, as I understand it. That's just one
00:05:27.080 --> 00:05:32.080
of them, though, I guess, that's mediated by Viagra. And that drug is approved, or has
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an FDA approval, for erectile dysfunction.
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What is it about nitric oxide that makes it so dangerous and responsible for things like
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cardiac arrest, stroke, arrhythmias, and also increased ocular pressure, which most people
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wouldn't even associate with Viagra, but I've had several people who have used it and have
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had heart attack and stroke. And that prompted me to even look at it as being something that
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should definitely be taken seriously. And I know also the kind of recreational drug
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users who use poppers, exactly the same compound, has some very damaging effects on the body.
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What's your take on nitric oxide?
00:06:16.080 --> 00:06:27.080
Speaking of poppers, several of the early theorists of AIDS were blaming it on whatever
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the chemical is. I guess it's nitric oxide that's produced from the poppers, some kind
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of nitric compound anyway. And they were arguing that that in itself was enough to account
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for the AIDS among the people who were using that as a pleasure drug. But in the 1980s,
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everyone knew nitric oxide primarily as a toxic component of smog. So when people started
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discovering that it was being produced in small amounts in the body, immediately they
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started looking for the parallels with smog poisoning, lung injury, circulatory disease,
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and so on. And one of the first things they found was that it kills the beta cells in
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the pancreas that produce insulin. So in the early 1940s, there was this flurry of papers
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demonstrating that our internal smog is just as toxic as Los Angeles smog. But then the
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Viagra patent and publicity came out in the later 1990s. And right then, suddenly the
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medical publications all found that it was a glorious, protective, natural, protecting
00:08:04.080 --> 00:08:11.080
just about every function you can think of, making you smarter, have more endurance, and
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all kinds of good things. But then after a few years, I guess the investment in publicity
00:08:20.080 --> 00:08:29.080
started wearing off and people started coming back to the diabetes producing effects and
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looking at what it's actually doing biochemically. The basic way it causes harm probably is that
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it is kind of parallel to the effects of carbon monoxide or cyanide in being a competitor
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for oxygen in the mitochondria, the enzymes that produce most of our energy. It in several
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ways knocks out not only the key final respiratory enzyme, cytochrome oxidase, but it poisons
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the previous electron transporting parts of the mitochondrion too. So simply turning off
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the energy supply can account for a lot of its problems. But it also, when you're stopping
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the oxidative run through the mitochondrion, the mitochondrion starts leaking, in effect,
00:09:44.080 --> 00:09:53.080
electrons that have no place to go. And the whole cell shifts over to a reduced chemical
00:09:53.080 --> 00:10:02.080
state. The electrons aren't being constantly drawn down. And so the balance, if you imagine
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a stream of electrons falling steadily towards oxygen, when you cut off that, they accumulate
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and float back. And literally the reducing environment shifts the whole balance of the
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self-reduced sulfur compounds and it's expressed all the way out to the surface. And the surface
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properties of the cell change. And there are some enzymes right across the surface so that
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this reducing energy from inside the cell is available to reduce oxygen outside the
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cells. And mitochondria aren't using it productively. In fact, this cloud of excess electrons flows
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through the enzyme called NADPH oxidase and directly reduces oxygen on the surface. And
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that produces superoxide, possibly toxic free radical, which then produces hydrogen peroxide.
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And in the immune cells that are under stress, that's considered productive because it helps
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to break down bacteria or whatever is exciting, disturbing the white blood cell. So this toxic
00:11:40.080 --> 00:11:53.080
oxidative burst has its useful aspects, but probably it's one of the better outcomes rather
00:11:53.080 --> 00:12:08.080
than just using the hydrogen peroxide directly or producing nitric oxide. This hydrogen peroxide
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can be used to oxidize chloride that is always present into hypochlorite, which becomes one
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of the very strong germ digesting chemicals that when a phagocyte has eaten something,
00:12:28.080 --> 00:12:35.080
then basically it's like Clorox. It helps break down the particle.
00:12:35.080 --> 00:12:43.080
Okay, so in general, the nitric oxide forms of a pretty energy wasteful mechanism and
00:12:43.080 --> 00:12:47.080
also damaging in its free radical producing effects.
00:12:47.080 --> 00:12:59.080
Yeah, this shift of the whole cell away from oxidation starts that whole process that people
00:12:59.080 --> 00:13:05.080
are still just starting to put together the whole picture of how it fits into physiology.
00:13:05.080 --> 00:13:13.080
But it has its effects on the nervous system that people are now seeing that Parkinson's
00:13:13.080 --> 00:13:25.080
disease, for example, has the signs that nitric oxide is one of the central damaging components
00:13:25.080 --> 00:13:29.080
of the dopamine system.
00:13:29.080 --> 00:13:36.080
Okay, you're listening to Ask Your Herb Doctor on KMED Galbraith 91.1 FM. From 7.30 to the
00:13:36.080 --> 00:13:41.080
end of the show at 8 o'clock, callers are invited to ask questions about this month's
00:13:41.080 --> 00:13:46.080
subject of nitric oxide and the ramifications thereof. It doesn't have to be specifically
00:13:46.080 --> 00:13:51.080
about this subject. I know people often call in about other subjects that Dr. Peat's well
00:13:51.080 --> 00:13:56.080
versed in, like thyroid, etc. But the number here in the area is 9233911, or if you're
00:13:56.080 --> 00:14:02.080
outside the area, there's a toll-free number, which is 1800 KMUD RAD.
00:14:02.080 --> 00:14:12.080
So, so far as the damaging effects of nitric oxide are concerned, I think there are three
00:14:12.080 --> 00:14:18.080
species of nitric oxide, and the one I think that's most commonly referenced in PubMed
00:14:18.080 --> 00:14:24.080
and other scientific literature for its effects, both negative and for the small beneficial
00:14:24.080 --> 00:14:33.080
effect of its burst, energy burst effect on bacteria, etc., is the inducible nitric oxide
00:14:33.080 --> 00:14:39.080
synthase. And that's been implicated in causing an increased severity of disease in quite
00:14:39.080 --> 00:14:45.080
a few different models, one of which was a herpes simplex model and kephalitis, which
00:14:45.080 --> 00:14:51.080
is a brain inflammation in mice. And then I saw other references as well to chronic
00:14:51.080 --> 00:14:56.080
viral hepatitis in man, is definitely being aggravated by nitric oxide, and potentially
00:14:56.080 --> 00:15:04.080
nitric oxide suppression might be a useful treatment for people suffering from chronic
00:15:04.080 --> 00:15:10.080
hepatitis. What are the most reasonable ways of blocking nitric oxide synthesis in the
00:15:10.080 --> 00:15:14.080
body, or at least managing its production and providing a buffer to it, so that you
00:15:14.080 --> 00:15:22.080
can maintain the little nitric oxide that is beneficial whilst keeping in check any
00:15:22.080 --> 00:15:31.080
excess? The body has its various natural ways of keeping it under control. For example,
00:15:31.080 --> 00:15:40.080
progesterone inhibits the enzyme that makes nitric oxide, while estrogen excites and activates
00:15:40.080 --> 00:15:50.080
that enzyme. And so when the cell is stabilized by a generous amount of progesterone and related
00:15:50.080 --> 00:16:00.080
neuro steroids, the stabilizing things, including pregnenolone, those hold down the production.
00:16:00.080 --> 00:16:09.080
Anything that irritates the cell and excites it, the endotoxin from the intestine is probably
00:16:09.080 --> 00:16:19.080
the biggest single constant promoter of the production of nitric oxide. And sometimes
00:16:19.080 --> 00:16:28.080
serotonin and histamine, which are produced in reaction to endotoxin and other irritating
00:16:28.080 --> 00:16:38.080
things, these can increase in various tissues. Serotonin and histamine can increase the formation
00:16:38.080 --> 00:16:53.080
of nitric oxide. In some situations, caffeine and similar drugs that are known to have a
00:16:53.080 --> 00:17:02.080
variety of protective antitoxic effects are acting by locally in a certain type of tissue,
00:17:02.080 --> 00:17:15.080
turning down the nitric oxide production. But in recent years, the old dye, it was used
00:17:15.080 --> 00:17:25.080
as a treatment for malaria 100 years ago, called methylene blue. It's a common lab chemical
00:17:25.080 --> 00:17:32.080
used for showing the presence of a reducing compound. For example, vitamin C turns it
00:17:32.080 --> 00:17:45.080
white. Lots of people use it to demonstrate chemistry in a visible form. It's being used
00:17:45.080 --> 00:17:56.080
for a tremendous variety of therapeutic purposes. And simply by turning down nitric oxide, which
00:17:56.080 --> 00:18:04.080
causes so many bad effects, methylene blue is having very positive effects in this great
00:18:04.080 --> 00:18:16.080
variety of things, including herpes and other viral, chronic viral diseases.
00:18:16.080 --> 00:18:26.080
The recent news about the Ebola virus, some people have noticed that one of the things,
00:18:26.080 --> 00:18:35.080
if the patient is going to die, their nitric oxide level in the blood is very high. And
00:18:35.080 --> 00:18:42.080
it's what is causing the blood vessels to leak and break down, causing blood to leak
00:18:42.080 --> 00:18:50.080
out every place that it shouldn't. But you see something similar in ordinary influenza
00:18:50.080 --> 00:18:59.080
and other viral infections. The blood vessels tend to become leaky and produce swelling
00:18:59.080 --> 00:19:07.080
and a lot of very common side effects that you see in diseases of all sorts.
00:19:07.080 --> 00:19:13.080
What would you think would be a good short-term approach to that, to block that?
00:19:13.080 --> 00:19:24.080
From what's available presently, niacinamide and progesterone are things that are commonly
00:19:24.080 --> 00:19:33.080
available. But methylene blue is probably, when it's available, it's probably a good
00:19:33.080 --> 00:19:43.080
emergency thing to turn off the massive amounts of overproduced nitric oxide.
00:19:43.080 --> 00:19:50.080
I did read an article, I think there were several references to methylene blue and its
00:19:50.080 --> 00:19:56.080
use either promoting or suppressing depending on a dose. And it seemed like very small amounts
00:19:56.080 --> 00:20:03.080
of methylene blue were having this favorable suppressive activity where larger amounts
00:20:03.080 --> 00:20:05.080
could actually cause...
00:20:05.080 --> 00:20:14.080
Yeah, some of the toxicity experiments have been kind of ridiculous in which they feed
00:20:14.080 --> 00:20:22.080
rats the equivalent, if for a person it would be an ounce or two of crystalline methylene
00:20:22.080 --> 00:20:34.080
blue, which it would just that amount of concentrated any chemical is going to be harmful. But it's
00:20:34.080 --> 00:20:46.080
been 25 years ago, someone did a very well-controlled study of severe depressed people. 15 milligrams
00:20:46.080 --> 00:20:59.080
per day was all it took to relieve severe depression. And the side effects of even many
00:20:59.080 --> 00:21:05.080
times higher doses than that are essentially zero.
00:21:05.080 --> 00:21:18.080
Two studies, one by the NIH six years ago and one more recent, gave graded doses up
00:21:18.080 --> 00:21:25.080
to what would be the equivalent of about four or five or six grams a day for a person of
00:21:25.080 --> 00:21:34.080
the crystalline material, many times higher than the curative antidepressive dose. And
00:21:34.080 --> 00:21:43.080
they did it for the whole lifespan of rats and mice and saw no life-shortening effects
00:21:43.080 --> 00:21:51.080
in either rats or mice. But in female mice, in both studies, they saw an extension of
00:21:51.080 --> 00:21:55.080
the maximum lifespan with the highest dose.
00:21:55.080 --> 00:22:06.080
So in these ridiculously high doses, many times, I guess about five to 10 times higher
00:22:06.080 --> 00:22:14.080
than the dose Paul Ehrlich used more than a hundred years ago to treat malaria. And
00:22:14.080 --> 00:22:22.080
he cured two cases of malaria in a period of just a couple of weeks, giving five doses
00:22:22.080 --> 00:22:33.080
a day of 100 milligrams each time orally. But with very much smaller doses, you see
00:22:33.080 --> 00:22:41.080
changes in the brain and reduced stress and curing depression and so on.
00:22:41.080 --> 00:22:49.080
But with several times higher doses than he used to cure malaria, you still don't see
00:22:49.080 --> 00:22:59.080
any harmful effects. And in animal experiments, it took one of the gigantic doses equivalent
00:22:59.080 --> 00:23:06.080
to, I think it was about eight grams a day for a person before it stopped showing the
00:23:06.080 --> 00:23:09.080
simple antidepressive actions.
00:23:09.080 --> 00:23:15.080
Now, do you think the effects of methylene blue are, there's probably multiple effects,
00:23:15.080 --> 00:23:24.080
but I wonder if any of the electron quenching or electrical stabilizing activity of methylene
00:23:24.080 --> 00:23:32.080
blue might be responsible for interacting with different proteins and that kind of...
00:23:32.080 --> 00:23:42.080
Yeah, one of the known mechanisms is that it can receive electrons from the mediator
00:23:42.080 --> 00:23:51.080
that receives them from glucose. And NADH, for example, can be oxidized and then the
00:23:51.080 --> 00:23:59.080
methylene blue can pass those electrons onto the part of the mitochondrion that is still
00:23:59.080 --> 00:24:09.080
working, bypassing damaged parts of the mitochondrion. So it can act like the missing enzyme, simply
00:24:09.080 --> 00:24:22.080
restoring mitochondrial function. But in subtler ways, for example, the receptor that causes
00:24:22.080 --> 00:24:31.080
excitotoxic damage from overdoses of glutamic acid, for example, anything that is depleting
00:24:31.080 --> 00:24:42.080
the brain of energy while stimulating it activates these glutamate receptors. And there are two
00:24:42.080 --> 00:24:52.080
sulfur groups in those proteins that respond to excitotoxins that methylene blue oxidizes
00:24:52.080 --> 00:24:59.080
those and turns off the receptor and stops the excitotoxic process. And that's one of
00:24:59.080 --> 00:25:07.080
the ways the excitotoxic process is one of the things that turns on nitric oxide production
00:25:07.080 --> 00:25:15.080
going ahead and killing the cell. That's why the excited state is toxic, largely because
00:25:15.080 --> 00:25:19.080
of the production of nitric oxide.
00:25:19.080 --> 00:25:24.080
Okay, now I guess methylene blue is not an FDA-controlled substance or anything. I think
00:25:24.080 --> 00:25:29.080
it's fairly widely available. It's just a dye, isn't it? I think typically it's known
00:25:29.080 --> 00:25:32.080
as a dye. I know it's a tissue stain.
00:25:32.080 --> 00:25:39.080
And fish stores use it. I'm not sure how they use it, but it's for sterilizing aquariums
00:25:39.080 --> 00:25:48.080
or something. And fish farmers use it to cure various fish infections.
00:25:48.080 --> 00:25:54.080
Okay, well, people listening perhaps might want to start looking up methylene blue and
00:25:54.080 --> 00:26:03.080
its implications in the treatment and/or prevention of different degenerative conditions. So extremely
00:26:03.080 --> 00:26:09.080
cheap, I'm sure, not all patented, not controlled. And if there's some good studies coming out
00:26:09.080 --> 00:26:14.080
showing methylene blue's positive effects in blocking nitric oxide, I think that could
00:26:14.080 --> 00:26:20.080
be well worth people looking at as an alternative to many of the drugs that people might be
00:26:20.080 --> 00:26:22.080
using for different conditions.
00:26:22.080 --> 00:26:23.080
Okay.
00:26:23.080 --> 00:26:31.080
I've counted about six different ways that methylene blue stops or blocks the production
00:26:31.080 --> 00:26:34.080
of nitric oxide.
00:26:34.080 --> 00:26:40.080
Okay, go on. Do you want to share them?
00:26:40.080 --> 00:26:53.080
No. The excitotoxic thing was one, preventing excess polymerization of the microtubules.
00:26:53.080 --> 00:27:04.080
Another, probably increasing progesterone production, inhibiting estrogen production.
00:27:04.080 --> 00:27:13.080
But probably the most important thing people should do is to start being critical about
00:27:13.080 --> 00:27:21.080
the tremendous amount of propaganda selling the idea that people should eat more arginine
00:27:21.080 --> 00:27:24.080
to increase their nitric oxide production.
00:27:24.080 --> 00:27:33.080
Wow. Wow. Yeah. I don't know, it always amazes me how this stuff actually comes into circulation
00:27:33.080 --> 00:27:44.080
as "common knowledge" and how easily influenced the media is by Big Pharma. Anyway, not to
00:27:44.080 --> 00:27:49.080
go on too much about that, because we could probably go on forever about how Big Pharma
00:27:49.080 --> 00:27:53.080
have their hooks all over. Anyway, it's coming up for 7.30. I've seen the lights flashing
00:27:53.080 --> 00:27:56.080
a couple of times, and I don't know if anyone's on the line at the moment. No shaking his
00:27:56.080 --> 00:27:58.080
head, must have gone off. Okay, no problem.
00:27:58.080 --> 00:28:02.080
You're listening to Ask Your Ob-Docs, we're on KMED Gallup 91.1 FM. From now until the
00:28:02.080 --> 00:28:06.080
end of the show at 8 o'clock, you're invited to call in any questions, either related or
00:28:06.080 --> 00:28:12.080
unrelated to this month's subject of nitric oxide and how to control its damaging effects.
00:28:12.080 --> 00:28:19.080
Dr. Raymond Peat is with us in the studio. He's a pretty foremost authority on lots of
00:28:19.080 --> 00:28:27.080
different subjects surrounding hormones and aging and all the interactions thereon. He's
00:28:27.080 --> 00:28:33.080
with us in the show. We have a caller on the line already, look at that. Okay, caller,
00:28:33.080 --> 00:28:35.080
you're on the air, and where are you from?
00:28:35.080 --> 00:28:50.080
I'm from Southern Humboldt here. Okay. Yeah. John, I wanted to know if all of the estrogen
00:28:50.080 --> 00:28:56.080
imitators that are around us in the environment that we've created for ourselves to live in
00:28:56.080 --> 00:29:00.080
are also something that'll put us at risk?
00:29:00.080 --> 00:29:03.080
Very much, very much so, yeah. That's it.
00:29:03.080 --> 00:29:08.080
I think I've seen that bisphenol A activates nitric oxide production.
00:29:08.080 --> 00:29:16.080
There you go, and that's an estrogen promoter, or mimic. Yeah, okay, so environmental estrogens
00:29:16.080 --> 00:29:22.080
very much have a negative impact on our health, many of which have come from petrochemical
00:29:22.080 --> 00:29:28.080
industry, plastics industry, etc. Dr. Peat, what do you think some of the most damaging
00:29:28.080 --> 00:29:32.080
environmental estrogens that you know of that are...
00:29:32.080 --> 00:29:40.080
Oh, the natural estrogen is... It's damaging enough.
00:29:40.080 --> 00:29:48.080
Yeah, it's through the sewage, it's getting into the rivers, and for the environment,
00:29:48.080 --> 00:29:56.080
I think that the natural estrogen and the birth control estrogens that are many times
00:29:56.080 --> 00:30:05.080
stronger than natural estrogen are showing up in all of the downstream waterways that
00:30:05.080 --> 00:30:09.080
receive sewage. So wastewater management does not selectively
00:30:09.080 --> 00:30:15.080
remove hormones from the water, then, are you saying? It's found... I wonder if it's
00:30:15.080 --> 00:30:20.080
reasonable to posit that there is detectable amounts in drinking water, even.
00:30:20.080 --> 00:30:26.080
Well, as a sewer board person, I can tell you that one of the ways that they tell whether
00:30:26.080 --> 00:30:32.080
water is coming from a sewage system or from nature is they look for caffeine, that's considered
00:30:32.080 --> 00:30:37.080
one of the chemicals that makes it through and is a marker for sewage as opposed to animal
00:30:37.080 --> 00:30:41.080
waste or whatever. So yeah, a lot of those chemicals do make it through.
00:30:41.080 --> 00:30:43.080
Okay, did we have any other questions?
00:30:43.080 --> 00:30:55.080
Oh yeah, the other part of my question was, is there a plant or an herb that actually
00:30:55.080 --> 00:31:01.080
produces or mimics methylene blue that you can ingest instead of...
00:31:01.080 --> 00:31:13.080
Oh, I've been looking around at various molecules and it was a precursor for many of the drugs,
00:31:13.080 --> 00:31:22.080
the tricyclic antidepressants and tricyclic antihistamines and anti-inflammatories, I
00:31:22.080 --> 00:31:30.080
think all grew out of the dye industry that methylene blue was one of the very first examples
00:31:30.080 --> 00:31:42.080
of, but it's a three ring molecule and that seems probably because it's structurally roughly
00:31:42.080 --> 00:31:50.080
the same size and shape as the steroid hormones, it probably can get into many of the places
00:31:50.080 --> 00:32:01.080
that our natural steroids act. So I've looked around at plants that make analogous things.
00:32:01.080 --> 00:32:10.080
The tetracyclines have many of the same anti-inflammatory effects, I suspect they're also working against
00:32:10.080 --> 00:32:16.080
nitric oxide, they just have one extra ring but in a very similar arrangement.
00:32:16.080 --> 00:32:24.080
And vitamin K and vitamin E are even analogous in some ways.
00:32:24.080 --> 00:32:40.080
Lopacho, a chemical from a South American tree, it's a dye that has many of the anti-inflammatory,
00:32:40.080 --> 00:32:44.080
anti-cancer properties of methylene blue. Spell that.
00:32:44.080 --> 00:32:58.080
Lopacho is a tabubui, so T-A-B-E-B-U-I-A, tabubui, and impetigenosa, it's a South American,
00:32:58.080 --> 00:33:04.080
tall South American hardwood, but it's used extensively for cancer as Dr. Peat mentioned,
00:33:04.080 --> 00:33:06.080
they call it pau de arco.
00:33:06.080 --> 00:33:15.080
Recently people are talking about a thing, an Asian herb, I think one of the names is
00:33:15.080 --> 00:33:25.080
black cumin, but it contains thymoquinone and the quinones are I think the essential
00:33:25.080 --> 00:33:38.080
model of the protective pro-oxidant stabilizing chemical and thymoquinone is considered to
00:33:38.080 --> 00:33:46.080
be a very powerful anti-inflammatory and I suspect that it'll turn out to be acting against
00:33:46.080 --> 00:33:48.080
excess nitric oxide.
00:33:48.080 --> 00:33:52.080
So it's a free radical quencher again, isn't it, the quinones?
00:33:52.080 --> 00:34:00.080
Yeah, that's just one of their many, they seem to activate the right kind of oxidation
00:34:00.080 --> 00:34:02.080
while quenching the bad kind.
00:34:02.080 --> 00:34:03.080
Okay, very good.
00:34:03.080 --> 00:34:05.080
All right, well thank you very much.
00:34:05.080 --> 00:34:08.080
Yeah, thanks for your caller, caller. We have three callers on the lines here, so let's
00:34:08.080 --> 00:34:12.080
get them one after the other. Caller, you're on the air, where are you from?
00:34:12.080 --> 00:34:13.080
Me?
00:34:13.080 --> 00:34:15.080
Hi, you're on the air, where are you from?
00:34:15.080 --> 00:34:16.080
Hi, Arcata.
00:34:16.080 --> 00:34:19.080
Arcata, okay. Go ahead, what's your question?
00:34:19.080 --> 00:34:22.080
Thanks, I've been listening to your show for a good four years or so.
00:34:22.080 --> 00:34:28.080
A couple of quick review questions from the past that I've been wondering about for a
00:34:28.080 --> 00:34:35.080
long time. It was mentioned some time ago about a nutrient I believe that could help
00:34:35.080 --> 00:34:40.080
remediate or, you know, fix the earlobe crease. Does that ring any bell?
00:34:40.080 --> 00:34:42.080
What was the last thing you said?
00:34:42.080 --> 00:34:43.080
Earlobe crease?
00:34:43.080 --> 00:34:44.080
Oh, the earlobe.
00:34:44.080 --> 00:34:45.080
Earlobe crease, yeah.
00:34:45.080 --> 00:34:47.080
That's a thyroid deficiency, isn't it?
00:34:47.080 --> 00:34:51.080
Yeah, I think it is mainly a thyroid deficiency.
00:34:51.080 --> 00:34:58.080
Okay, and did I hear at the time a simple recommendation for correction of that? Was
00:34:58.080 --> 00:35:03.080
there a nutrient or is that a much more complex matter to address?
00:35:03.080 --> 00:35:12.080
I think the main thing causing hypothyroidism in so many people is an excess of the polyunsaturated
00:35:12.080 --> 00:35:20.080
fatty acids because they're able to block the production of thyroid, its transport and
00:35:20.080 --> 00:35:29.080
its action. So, they're very capable of antagonizing thyroid function.
00:35:29.080 --> 00:35:36.080
So, to avoid all the nuts and seeds that contain liquid oils in them, so nuts and seeds are
00:35:36.080 --> 00:35:41.080
principally the kind of polyunsaturated sources and obviously there are other polyunsaturated
00:35:41.080 --> 00:35:47.080
yet commonly available in food that you should definitely avoid. So, any of the liquid oils,
00:35:47.080 --> 00:35:48.080
obviously.
00:35:48.080 --> 00:35:50.080
What about like coconut oil? Is that for?
00:35:50.080 --> 00:35:56.080
Coconut oil is saturated, so that's good. Dr. Peat's always recommending coconut oil
00:35:56.080 --> 00:36:02.080
and butter as being the two saturated sources of fat. That should be the most consumed.
00:36:02.080 --> 00:36:07.080
And then to avoid all the liquids, liquid polyunsaturates, obviously fish oil being
00:36:07.080 --> 00:36:08.080
the worst.
00:36:08.080 --> 00:36:12.080
Okay. Whoa, like cod liver oil?
00:36:12.080 --> 00:36:17.080
That too, but I think, Dr. Peat, don't you say that the vitamin content in cod liver
00:36:17.080 --> 00:36:18.080
oil...
00:36:18.080 --> 00:36:24.080
Oh, yeah, if you don't have any better source, cod liver oil is a great source of vitamin
00:36:24.080 --> 00:36:25.080
D.
00:36:25.080 --> 00:36:26.080
Yeah.
00:36:26.080 --> 00:36:28.080
But it's better to get sunlight.
00:36:28.080 --> 00:36:29.080
Yeah.
00:36:29.080 --> 00:36:30.080
Okay.
00:36:30.080 --> 00:36:33.080
Can I have one quick other question?
00:36:33.080 --> 00:36:34.080
Go ahead.
00:36:35.080 --> 00:36:40.080
There was something that came up about eating carrots and I don't know what the term would
00:36:40.080 --> 00:36:46.080
be, but I want to say like an astringent or a cleaning or a purifying or...
00:36:46.080 --> 00:36:47.080
An antiseptic, yeah.
00:36:47.080 --> 00:36:53.080
...a helpful aspect of eating carrots. It was recommended that carrots be cut diagonally
00:36:53.080 --> 00:36:59.080
as a juicer and a cook, I guess, of my own food. I thought that was a bit peculiar and
00:36:59.080 --> 00:37:01.080
I wondered if that could be elaborated upon.
00:37:01.080 --> 00:37:07.080
I think Dr. Peat's always mentioned that grated carrots to increase the surface area is the
00:37:07.080 --> 00:37:12.080
mechanism that's preferred and that's basically is a antiseptic, if you like, for the gut,