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mobio.owl
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mobio.owl
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<?xml version="1.0"?>
<rdf:RDF xmlns="http://purl.obolibrary.org/obo/mobile_elements_ontology.owl#"
xml:base="http://purl.obolibrary.org/obo/mobile_elements_ontology.owl"
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:owl="http://www.w3.org/2002/07/owl#"
xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
xmlns:xml="http://www.w3.org/XML/1998/namespace"
xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
xmlns:obo="http://purl.obolibrary.org/obo/">
<owl:Ontology rdf:about="http://purl.obolibrary.org/obo/mobile_elements_ontology.owl">
<oboInOwl:date rdf:datatype="http://www.w3.org/2001/XMLSchema#string">23:10:2019 11:30</oboInOwl:date>
<oboInOwl:auto-generated-by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">cv2obo</oboInOwl:auto-generated-by>
<oboInOwl:hasOBOFormatVersion rdf:datatype="http://www.w3.org/2001/XMLSchema#string">1.2</oboInOwl:hasOBOFormatVersion>
<oboInOwl:default-namespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:default-namespace>
<oboInOwl:saved-by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CARD</oboInOwl:saved-by>
</owl:Ontology>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Annotation properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/IAO_0000115 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115">
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">definition</rdfs:label>
</owl:AnnotationProperty>
<!-- http://www.geneontology.org/formats/oboInOwl#auto-generated-by -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#auto-generated-by"/>
<!-- http://www.geneontology.org/formats/oboInOwl#date -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#date"/>
<!-- http://www.geneontology.org/formats/oboInOwl#default-namespace -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#default-namespace"/>
<!-- http://www.geneontology.org/formats/oboInOwl#hasDbXref -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref">
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">database_cross_reference</rdfs:label>
</owl:AnnotationProperty>
<!-- http://www.geneontology.org/formats/oboInOwl#hasExactSynonym -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym">
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">has_exact_synonym</rdfs:label>
</owl:AnnotationProperty>
<!-- http://www.geneontology.org/formats/oboInOwl#hasOBOFormatVersion -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasOBOFormatVersion">
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">has_obo_format_version</rdfs:label>
</owl:AnnotationProperty>
<!-- http://www.geneontology.org/formats/oboInOwl#hasOBONamespace -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasOBONamespace">
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">has_obo_namespace</rdfs:label>
</owl:AnnotationProperty>
<!-- http://www.geneontology.org/formats/oboInOwl#id -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
<!-- http://www.geneontology.org/formats/oboInOwl#saved-by -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#saved-by"/>
<!-- http://www.geneontology.org/formats/oboInOwl#shorthand -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#shorthand">
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">shorthand</rdfs:label>
</owl:AnnotationProperty>
<!-- http://www.w3.org/2000/01/rdf-schema#label -->
<owl:AnnotationProperty rdf:about="http://www.w3.org/2000/01/rdf-schema#label"/>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Object Properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/RO_regulates -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_regulates">
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">RO:regulates</oboInOwl:hasDbXref>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">regulates</oboInOwl:id>
<oboInOwl:shorthand rdf:datatype="http://www.w3.org/2001/XMLSchema#string">regulates</oboInOwl:shorthand>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">regulates</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO#_is_a -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO#_is_a">
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">RO:is_a</oboInOwl:hasDbXref>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">is_a</oboInOwl:id>
<oboInOwl:shorthand rdf:datatype="http://www.w3.org/2001/XMLSchema#string">is_a</oboInOwl:shorthand>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">is_a</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO#_part_of -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO#_part_of">
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">RO:part_of</oboInOwl:hasDbXref>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">part_of</oboInOwl:id>
<oboInOwl:shorthand rdf:datatype="http://www.w3.org/2001/XMLSchema#string">part_of</oboInOwl:shorthand>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">part_of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO#_participates_in -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO#_participates_in">
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">RO:participates_in</oboInOwl:hasDbXref>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">participates_in</oboInOwl:id>
<oboInOwl:shorthand rdf:datatype="http://www.w3.org/2001/XMLSchema#string">participates_in</oboInOwl:shorthand>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">participates_in</rdfs:label>
</owl:ObjectProperty>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Classes
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/MOBIO_0000001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000001">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000184"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Mobile genetic elements (MGEs) are a type of genetic material, a segment of DNA or RNA, that is capable of movement around a genome or that can be transferred from one species or replicon to another. These include transposons, plasmids, bacteriophages, and genomic islands. The mechanism of movement may be self-encoded or may rely on other enzymes and structures, such as a pilus. In bacteria, MGEs are often associated with the movement of antibiotic resistance genes and virulence factors from one species to another, for example by plasmid-mediated transfer.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000001</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile genetic element</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000002 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000002">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000001"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A plasmid is a small, circular, double-stranded DNA molecule that is distinct from a cell's chromosomal DNA. Plasmids naturally exist in bacterial cells, and they also occur in some eukaryotes. Often, the genes carried in plasmids provide bacteria with genetic advantages, such as antibiotic resistance. Plasmids have a wide range of lengths, from roughly one thousand DNA base pairs to hundreds of thousands of base pairs.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000002</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">plasmid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000003 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000003">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000001"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO#_part_of"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000002"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A transposable element (TE or transposon) is a DNA sequence that can change its position within a genome, sometimes creating or reversing mutations and altering the cell's genome size. Transposition often results in duplication of the same genetic material. Transposons were originally discovered as jumping genes by Barbara McClintock.</obo:IAO_0000115>
<oboInOwl:hasExactSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">transposon</oboInOwl:hasExactSynonym>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000003</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">transposable element</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000004 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000004">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000001"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Bacteriophage are viral infectious agents with bacterial host organisms. Bacteriophage infect and replicate inside bacterial host cells, causing cell lysis as viral particles replicate. Bacteriophage are involved in DNA transfer between host organisms at low frequency through transduction: when segments of host DNA is accidentally packaged with the viral DNA, then integrated into a new host genome and later inherited.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000004</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">bacteriophage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000006 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000006">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000002"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">These plasmids contain genes that code for bacteriocins, proteins that can kill other bacteria.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000006</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Col Plasmids</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000007 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000007">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000002"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Fertility F-plasmids contain tra genes and are capable of conjugation resulting in the expression of sex pilli.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000007</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Fertility F-Plasmids</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000008 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000008">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000002"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">These plasmids contain genes that provide resistance against antibiotics or poisons. Historically known as R-factors, before the nature of plasmids was understood.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000008</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Resistance Plasmids</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000009 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000009">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000002"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">These plasmids enable the digestion of unusual substances, e.g. toluene and salicylic acid.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000009</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Degradative Plasmids</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000010 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000010">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000002"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">which turn the bacterium into a pathogen</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000010</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Virulence Plasmids</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000011 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000011">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000016"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">The set of specific processes that needed for plasmid partition, stability, replication, and mobility. These are all processes that allow for the plasmid to move between organisms.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000011</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mechanism of plasmid maintenance</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000012 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000012">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000011"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Any process or set of processes through which plasmid replication is initiated.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000012</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mechanism of replication</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000013 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000013">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000012"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Replication by the Theta Mechanism - opening of the strands followed by RNA priming</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000013</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">theta type</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000014 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000014">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000012"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">strand displacement replication. Opening of the strands followed by RNA priming</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000014</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">strand displacement</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000015 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000015">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000012"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A mechanism of plasmid replication in which the two strands are asynchronously copied, with one strand initially forming a single-stranded circle.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000015</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">rolling circle replication</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000016 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000016">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000184"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Molecular mechanisms involved in the intracellular and intercellular transfer, integration, stabilization and recombination of mobile genetic elements.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000016</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">process or mechanism of genetic mobility</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000017 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000017">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000196"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO#_part_of"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000007"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Conjugation is the process by which one bacterium transfers genetic material to another through direct contact. During conjugation, one bacterium serves as the donor of the genetic material, and the other serves as the recipient.</obo:IAO_0000115>
<oboInOwl:hasExactSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Conjugation</oboInOwl:hasExactSynonym>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000017</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">conjugative transfer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000019 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000019">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000011"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Stabilization mechanisms facilitate and promote the survival of plasmids in their host cells. This includes mechanisms that allow for the survival of the host cell itself in harsh conditions.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000019</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mechanism of stabilization</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000020 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000020">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000016"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Transformation refers to process of free DNA uptake by competent cells and subsequent integration and functional expression of genes. Extracellular DNA continually enters the environment upon release from decomposing cells, disrupted cells, viral particles or excretion from living cells.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000020</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">transformation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000021 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000021">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000019"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A toxin-antitoxin system is a set of two or more closely linked genes that together encode both a protein 'poison' and a corresponding 'antidote'. When these systems are contained on plasmids – transferable genetic elements – they ensure that only the daughter cells that inherit the plasmid survive after cell division. If the plasmid is absent in a daughter cell, the unstable anti-toxin is degraded and the stable toxic protein kills the new cell; this is known as 'post-segregational killing' (PSK).</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000021</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Toxin-antitoxin system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000022 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000022">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000021"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Type I toxin-antitoxin systems rely on the base-pairing of complementary antitoxin RNA with the toxin's mRNA. Translation of the mRNA is then inhibited either by degradation via RNase III or by occluding the Shine-Dalgarno sequence or ribosome binding site.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000022</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Type I TA System</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000023 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000023">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000021"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">In this system a labile protein antitoxin tightly binds and inhibits the activity of a stable toxin. Type II systems are organised in operons with the antitoxin protein typically being located upstream of the toxin. The antitoxin inhibits the toxin by downregulating its expression.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000023</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Type II TA System</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000024 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000024">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000021"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Type III toxin-antitoxin systems rely on direct interaction between a toxic protein and an RNA antitoxin. The toxic effects of the protein are neutralised by the RNA gene.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000024</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Type III TA System</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000025 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000025">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000185"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">The process of conjugation requires several different types of subunits and complexes.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000025</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">conjugal transfer subunit or complex</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000026 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000026">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000025"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Protein involved in the conjugal transfer of DNA. First identified in conjugative plasmid R6K of E. coli.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000026</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pilX7</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000026"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Protein involved in the conjugal transfer of DNA. First identified in conjugative plasmid R6K of E. coli.</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:18375554</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:19717626</oboInOwl:hasDbXref>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000027 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000027">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000025"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Protein involved in conjugal transfer of DNA. First identified in conjugative plasmid R6K of E. coli.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000027</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pilX8</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000027"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Protein involved in conjugal transfer of DNA. First identified in conjugative plasmid R6K of E. coli.</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:18375554</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:19717626</oboInOwl:hasDbXref>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000028 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000028">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000188"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO#_part_of"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000006"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Colicin immunity proteins are plasmid encoded proteins necessary for protecting the cell against colicins. Colicins are toxins released by bacteria during times of stress</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000028</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">colicin immunity protein</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000029 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000029">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000025"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Protein involved in conjugal transfer of DNA. First identified in conjugative plasmid R6K of E. coli.
</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000029</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pilX9</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000029"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Protein involved in conjugal transfer of DNA. First identified in conjugative plasmid R6K of E. coli.
</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:18375554</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:19717626</oboInOwl:hasDbXref>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000030 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000030">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000025"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Protein involved in conjugal transfer of DNA. First identified in conjugative plasmid R6K of E. coli. It is homologous to type IV secretory pathway VirB10 protein</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000030</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pilX10</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000030"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Protein involved in conjugal transfer of DNA. First identified in conjugative plasmid R6K of E. coli. It is homologous to type IV secretory pathway VirB10 protein</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:18375554</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:19717626</oboInOwl:hasDbXref>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000031 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000031">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000025"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Protein involved in conjugal transfer of DNA. First identified in conjugative plasmid R6K of E. coli. It is homologous to P-type DNA transfer ATPase VirB11.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000031</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pilX11</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000031"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Protein involved in conjugal transfer of DNA. First identified in conjugative plasmid R6K of E. coli. It is homologous to P-type DNA transfer ATPase VirB11.</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:18375554</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:19717626</oboInOwl:hasDbXref>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000032 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000032">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000181"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">conjugal transfer protein - conjugal transfer protein TraG</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000032</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">taxB</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000032"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">conjugal transfer protein - conjugal transfer protein TraG</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:18375554</oboInOwl:hasDbXref>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000033 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000033">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000051"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO#_part_of"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000123"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Toxic component of a type II toxin-antitoxin (TA) module. A sequence-specific, ribosome-dependent mRNA endoribonuclease that inhibits translation during amino acid starvation (the stringent response). In vitro acts by cleaving mRNA with high codon specificity in the ribosomal A site between positions 2 and 3. The stop codon UAG is cleaved at a fast rate while UAA and UGA are cleaved with intermediate and slow rates. In vitro mRNA cleavage can also occur in the ribosomal E site after peptide release from peptidyl-tRNA in the P site as well as on free 30S subunits. In vivo cuts frequently in the first 100 codons, most frequently after the second and third base and rarely near the stop codon. Overexpression of RelE results in the inhibition of bacterial growth and a sharp decrease in colony-forming ability which is neutralized by the labile cognate antitoxin RelB. Overexpression also sharply increases persisters (cells that neither grow nor die in the presence of bactericidal agents and are largely responsible for high levels of biofilm tolerance to antimicrobials). Plays a role in dormancy when expressed in high-density cells in the absence of antitoxin RelB; amino acid starvation and an unidentified extracellular factor promote dormancy, while expression of antitoxin RelB restores cell culturability. Acts with RelB as a corepressor of relBE transcription, considerably increasing the repression of RelB alone. 2 RelB dimers bind to 2 operator sequences; DNA-binding and repression is stronger when complexed with toxin/corepressor RelE by conditional cooperativity.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000033</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">RelE</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000033"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Toxic component of a type II toxin-antitoxin (TA) module. A sequence-specific, ribosome-dependent mRNA endoribonuclease that inhibits translation during amino acid starvation (the stringent response). In vitro acts by cleaving mRNA with high codon specificity in the ribosomal A site between positions 2 and 3. The stop codon UAG is cleaved at a fast rate while UAA and UGA are cleaved with intermediate and slow rates. In vitro mRNA cleavage can also occur in the ribosomal E site after peptide release from peptidyl-tRNA in the P site as well as on free 30S subunits. In vivo cuts frequently in the first 100 codons, most frequently after the second and third base and rarely near the stop codon. Overexpression of RelE results in the inhibition of bacterial growth and a sharp decrease in colony-forming ability which is neutralized by the labile cognate antitoxin RelB. Overexpression also sharply increases persisters (cells that neither grow nor die in the presence of bactericidal agents and are largely responsible for high levels of biofilm tolerance to antimicrobials). Plays a role in dormancy when expressed in high-density cells in the absence of antitoxin RelB; amino acid starvation and an unidentified extracellular factor promote dormancy, while expression of antitoxin RelB restores cell culturability. Acts with RelB as a corepressor of relBE transcription, considerably increasing the repression of RelB alone. 2 RelB dimers bind to 2 operator sequences; DNA-binding and repression is stronger when complexed with toxin/corepressor RelE by conditional cooperativity.</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:12526800</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:15576765</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:18375554</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:21324908</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:22210768</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:9767574</oboInOwl:hasDbXref>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000034 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000034">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000187"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO#_participates_in"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000013"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO#_participates_in"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000014"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO#_participates_in"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000015"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Topoisomerases are enzymes that participate in the overwinding or underwinding of DNA. They bind to double-stranded DNA and cut the phosphate backbone of either one or both the DNA strands.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000034</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">DNA topoisomerase</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000035 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000035">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000034"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">The traE gene, first identified in plasmid RP4, is a homologue of E. coli DNA topoisomerase III.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000035</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">traE</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000035"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">The traE gene, first identified in plasmid RP4, is a homologue of E. coli DNA topoisomerase III.</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:18375554</oboInOwl:hasDbXref>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000036 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000036">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000187"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO#_participates_in"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000015"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Molecular chaperones are proteins that assist the covalent folding or unfolding and the assembly or disassembly of other macromolecular structures. Chaperones are present when the macromolecules perform their normal biological functions and have correctly completed the processes of folding and/or assembly. The chaperones are concerned primarily with protein folding. One major function of chaperones is to prevent both newly synthesized polypeptide chains and assembled subunits from aggregating into nonfunctional structures. Many chaperones are heat shock proteins because the tendency to aggregate increases as proteins are denatured by stress.
Molecular chaperones have been shown to be involved in both the assembly and disassembly of DNA replication complexes.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000036</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Molecular Chaperone</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000037 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000037">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000036"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Chaperone DnaJ, also known as Hsp40 (heat shock protein 40 kD), is a molecular chaperone protein. The J domain of DnaJ interacts with Hsp70 heat shock proteins. DnaJ heat-shock proteins play a role in regulating the ATPase activity of Hsp70 heat-shock proteins.</obo:IAO_0000115>
<oboInOwl:hasExactSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hsp40</oboInOwl:hasExactSynonym>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000037</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">DnaJ</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000037"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Chaperone DnaJ, also known as Hsp40 (heat shock protein 40 kD), is a molecular chaperone protein. The J domain of DnaJ interacts with Hsp70 heat shock proteins. DnaJ heat-shock proteins play a role in regulating the ATPase activity of Hsp70 heat-shock proteins.</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:18375554</oboInOwl:hasDbXref>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000038 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000038">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000190"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO#_part_of"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000003"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Class 2 transposons encode transposase, which is an enzyme that binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism.
</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000038</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">transposase</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000039 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000039">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000046"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">This protein is a specific topoisomerase involved in initiating replication. This protein is specifically required and may be rate-limiting for replication of the plasmid in vivo.
</obo:IAO_0000115>
<oboInOwl:hasExactSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">repC</oboInOwl:hasExactSynonym>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000039</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">replication initiation protein RepC</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000040 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000040">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000019"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000188"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">These proteins reduce chromate accumulation and are essential for chromate resistance. They are composed of one or two copies of this region. The short-chain CHR proteins form heterodimer transporters which efflux chromate ions from the cytoplasm, while the long chain CHR proteins appear to have arisen from a gene fusion event of two short chain transporters</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000040</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Chromate transport protein</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000041 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000041">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000187"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO#_participates_in"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000013"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO#_participates_in"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000014"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO#_participates_in"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000015"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids.</obo:IAO_0000115>
<oboInOwl:hasExactSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">DfrA</oboInOwl:hasExactSynonym>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000041</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Dihydrofolate reductase</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000042 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000042">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000104"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO#_part_of"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000043"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Class 1 Integrase is a site-specific recombination enzyme that is part of the class 1 integron system. It recognizes the recombination site, attI1, which is where it will catalyze the insertion of gene casettes.</obo:IAO_0000115>
<oboInOwl:hasExactSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Intl1</oboInOwl:hasExactSynonym>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000042</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Class 1 Integrase</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000042"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Class 1 Integrase is a site-specific recombination enzyme that is part of the class 1 integron system. It recognizes the recombination site, attI1, which is where it will catalyze the insertion of gene casettes.</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:18193080</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:8574395</oboInOwl:hasDbXref>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000043 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000043">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000016"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO#_part_of"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000002"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO#_part_of"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000003"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Integrons are genetic mechanisms that allow bacteria to adapt and evolve rapidly through the acquisition, stockpiling and differential expression of new genes. Additionally, an integron will usually contain one or more gene cassettes that have been incorporated into it.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000043</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">integron</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000044 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000044">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000045"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">DNA-binding transcriptional regulator. Protein that is involved in negative regulation of phenolic acid metabolism.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000044</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PadR family transcriptional regulator</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000045 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000045">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000190"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby orchestrating gene activity.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000045</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">transcriptional regulator of operons found in MGEs</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000046 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000046">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000187"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO#_participates_in"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000013"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO#_participates_in"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000014"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO#_participates_in"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000015"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">protein required for initiation of replication</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000046</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">replication initiation protein</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000047 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000047">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000046"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">This protein is essential for plasmid replication; it is involved in copy control functions</obo:IAO_0000115>
<oboInOwl:hasExactSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">RepA</oboInOwl:hasExactSynonym>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000047</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">replication initiation protein RepA</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000048 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000048">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000025"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO#_participates_in"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000017"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">papB may act as both positive and negative regulator of the pyelonephritis-associated pili (pap) pilin gene transcription. It is found in the pap operon.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000048</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Major pili subunit operon regulatory protein papB</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000049 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000049">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000191"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO#_part_of"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000023"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Type II systems are organized in operons with the antitoxin protein typically being located upstream of the toxin. The antitoxin inhibits the toxin by downregulating its expression.</obo:IAO_0000115>
<oboInOwl:hasExactSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">antitoxin</oboInOwl:hasExactSynonym>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000049</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Type II post-segregation antitoxin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000050 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000050">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000045"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">transcriptional regulator</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000050</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">C protein</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000051 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000051">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000191"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO#_part_of"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000023"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Type II systems are organised in operons with the antitoxin protein typically being located upstream of the toxin. The antitoxin inhibits the toxin by downregulating its expression.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000051</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Type II toxin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MOBIO_0000052 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MOBIO_0000052">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000049"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO#_part_of"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MOBIO_0000079"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Antitoxin component of a toxin-antitoxin (TA) module which inhibits the post-segregational killing (PSK) of plasmid-free cells, also referred to as a plasmid addiction system. Labile antitoxin with a half-life of about 1 hour in the presence of CcdB. Binds to and blocks the activity of CcdB; will also remove bound CcdB protein from the CcdB-GyrA complex by forming a CcdA-CcdB complex, a process termed rejuvenation. The N-terminal 36 residues are not required for rejuventation. Functions as a transcriptional corepressor for the ccdAB operon, repression also requires CcdB.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mobile_elements_ontology</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MOBIO:0000052</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CcdA</rdfs:label>
</owl:Class>