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Benzimadazole opoids #324

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Benzimadazole opoids #324

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ANUGAMAGE
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Benzimidazole opioids, often referred to as nitazenes, represent a subgroup of new psychoactive substances with a recent increase in fatal overdoses in the USA and Europe. With a variety of analogs emerging on the illicit drug market, forensic laboratories are challenged to identify these potent drugs.

@ANUGAMAGE ANUGAMAGE requested a review from Sulstice as a code owner September 11, 2024 07:41
@ANUGAMAGE ANUGAMAGE changed the title Benzimadazole opoids anu Benzimadazole opoids Sep 11, 2024
@Sulstice Sulstice requested a review from Lyq322 September 12, 2024 15:46
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@Lyq322 Check his PR and the list. Make sure it adheres to the rest of global-chem.

@Sulstice Sulstice added the 2.0 label Sep 13, 2024
@Sulstice Sulstice linked an issue Sep 13, 2024 that may be closed by this pull request
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Lyq322 commented Sep 22, 2024

Some of the molecules in this list doesn't match the description in the issue #311, is this intended?
image

For example, Metonitazene phenethyl homologue (Ethylene metonitazene) has two carbons instead of 1 between the benzimidazole and benzene rings.
('CCN(CC)CCN1C(CCC2=CC=C(OC)C=C2)=NC3=CC(N+=O)=CC=C31
Screenshot 2024-09-22 at 4 28 19 PM

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Ah, perhaps an extra carbon or something got added in. @ANUGAMAGE could you fix that?

@Sulstice Sulstice added this to the v2.0 milestone Sep 26, 2024
Signed-off-by: Anuththara Gamage(Anu) <90089876+ANUGAMAGE@users.noreply.github.com>
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@Lyq322 Instead of using description in the issue #311 (It was with limited number of molecules) I have used small molecules in https://en.wikipedia.org/wiki/List_of_benzimidazole_opioids#.

In there Metonitazene phenethyl homologue (Ethylene metonitazene) has two carbons instead of 1 between the benzimidazole and benzene rings. Those structures was based on multiple type of research articles so I think they are correct. (ChemDraw was used)

Signed-off-by: Anuththara Gamage(Anu) <90089876+ANUGAMAGE@users.noreply.github.com>
Signed-off-by: Anuththara Gamage(Anu) <90089876+ANUGAMAGE@users.noreply.github.com>
Signed-off-by: Anuththara Gamage(Anu) <90089876+ANUGAMAGE@users.noreply.github.com>
Signed-off-by: Anuththara Gamage(Anu) <90089876+ANUGAMAGE@users.noreply.github.com>
Signed-off-by: Anuththara Gamage(Anu) <90089876+ANUGAMAGE@users.noreply.github.com>
ANUGAMAGE and others added 6 commits November 8, 2024 13:16
…pioids/benzimidazole_opioids.py

Co-authored-by: Yuqing Liu <47932418+Lyq322@users.noreply.github.com>
Signed-off-by: Anuththara Gamage(Anu) <90089876+ANUGAMAGE@users.noreply.github.com>
…pioids/benzimidazole_opioids.py

Co-authored-by: Yuqing Liu <47932418+Lyq322@users.noreply.github.com>
Signed-off-by: Anuththara Gamage(Anu) <90089876+ANUGAMAGE@users.noreply.github.com>
…pioids/benzimidazole_opioids.py

Co-authored-by: Yuqing Liu <47932418+Lyq322@users.noreply.github.com>
Signed-off-by: Anuththara Gamage(Anu) <90089876+ANUGAMAGE@users.noreply.github.com>
…pioids/benzimidazole_opioids.py

Co-authored-by: Yuqing Liu <47932418+Lyq322@users.noreply.github.com>
Signed-off-by: Anuththara Gamage(Anu) <90089876+ANUGAMAGE@users.noreply.github.com>
…pioids/benzimidazole_opioids.py

Co-authored-by: Yuqing Liu <47932418+Lyq322@users.noreply.github.com>
Signed-off-by: Anuththara Gamage(Anu) <90089876+ANUGAMAGE@users.noreply.github.com>
…pioids/benzimidazole_opioids.py

Co-authored-by: Yuqing Liu <47932418+Lyq322@users.noreply.github.com>
Signed-off-by: Anuththara Gamage(Anu) <90089876+ANUGAMAGE@users.noreply.github.com>
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SS-180: Add Benzimadazole-Opoids
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