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Upgrade Libraries and deal with multi-nucleotide polymorphisms (MNP) #109

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sicotteh opened this issue Aug 25, 2022 · 0 comments
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@sicotteh
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Is there any way you could refactor the code to work with more recent tensorflow libraries?

SpliceAI does not work with multi-nucleotide polymorphisms(MNP), e.g.
2-bases mutating to 3 bases .. or in general N bases mutating into M bases. I tried both VCF-legal representations (padded 1 base before both alleles .. or not padding).

Currently only SNV, purely insertions, and purely deletions seem to work.

Is that a simple fix?

Hugues Sicottw

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