slicePASEF

[cutleraging]

Hello Fragpipe team,

Will there be support for slicePASEF soon? I saw this was mentioned in the latest diaPASEF paper, but when I try to use this option in the DiaNN module, it says it is not recognized.

Best,
Ronnie

[anesvi]

There are too many diagonal PASEF versions now, and none seem to be well supported by Bruker. There is ASMS2024 poster on diagonal PASEF (yet another term) showing that the gains are frankly minimal. We will support it if there is strong interest. People who work with these data -please contact us to discuss, we need some motivation.

[cutleraging]

I am using this for single cell applications. I have found that this does indeed increase my IDs. I am using a timsTOF HT. Would you like me to share some data?

[anesvi]

We can discuss a collaboration and possibly looking at your data - could you please contact me by email and I will connect you with the rest of my team working with diaPASEF data.