Hi Sam, Thank you for the tool and pipeline, since pigs_calc provide the SUM and three ansectry correction including Z_MostSimilarPop, Z_norm1, and Z_norm2, which of these scores is the most accurate to use in the further analyses, and do these ancestry normalization control for PGS confounders including the population stratification, or do we still need to use the top 10 PCs in the statistical analyses. Thank you.

[SalemWerdyani]

Hi! Thanks for using the PGS Catalog calculator (pgsc_calc).

If you need help with setting up the calculator, configuration options, or have questions about polygenic risk scores generally, the best place to ask is:

• GitHub discussions: https://github.com/PGScatalog/pgsc_calc/discussions

We prefer a public discussion forum instead of answering emails, so other people interested in PGS can find and learn from our discussions.

We also include answers to a lot of questions that get regularly asked in our documentation

• Documentation: https://pgsc-calc.readthedocs.io/en/latest/index.html