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Colocalization project

Consulting project

Authors: Ryan Schubert, Raqual Zazi and Jie Zhang

GOALS:

1.) Build a Pipeline to automate the usage of the software “coloc”

2.) Test the performance of “coloc” in different populations

Stretch Goals:

3.) Test a variety of the parameters in the software to test how they effect model performance

4.) Write thorough documentation of the pipeline and software

References

Coloc software: https://chr1swallace.github.io/coloc/index.html

Eliciting priors and relaxing the single causal variant assumption in colocalisation analyses https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1008720