Cant Get Randomizer to work

[HerrArglist]

I get the .exe to open, but when I click the randomize button all that happens is this:

Randomize!
Exception in Tkinter callback
Traceback (most recent call last):
File "tkinter_init_.py", line 1884, in call
File "randomizewindow.py", line 88, in
File "randomize.py", line 42, in RandomizeSkill
File "gen_skill_randomizer.py", line 11, in SkillRandom
File "bl3hotfixmod.py", line 105, in init
PermissionError: [Errno 13] Permission denied: 'skill_randomizer.bl3hotfix'

Hoping you may be able to make sense of what I am doing wrong.