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I've tried to rename these bam files and merged them as the input of Clipper.
I found no matter how many bam files I merged, the output of clipper would always have 2 replicates.
I also see another answer which said clipper can only dual with 2 replicates so it's better to use skipper.
Is that true? What should I do If I have multiple replicates and want to perform peak calling and normalization?
Hi eCLIP group,
I run eclip pipeline calls enriched peak regions (peak clusters) with CLIPPER.
I finally got bed file like this
Only 2 replicates in the output file.
I have 3 experiment data and 3 controls. I merged 3 experiment data with samtools and I expected to get 3 replicates in output files.
Could you give me some advise to solve this problem?
Thank you in advance.
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