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DESCRIPTION
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Package: mr.simss
Type: Package
Title: MR-SimSS: Mendelian Randomisation (MR) method that combats Winner's Curse using a simulated sample splitting approach
Version: 0.1.0
Authors@R: person("Amanda", "Forde", email = "amanda.forde@universityofgalway.ie",
role = c("aut", "cre"), comment = c(ORCID = "0000-0002-7940-3413"))
Description: Designed to provide users with a method, namely MR-SimSS, which uses simulated sample splitting in order to alleviate
Winner's Curse bias in MR causal effect estimates. This approach also takes into account sample overlap between the exposure and outcome genome-wide association studies. It
uses summary statistics from genome-wide association studies and works in combination with existing MR methods, such as IVW and MR-RAPS.
License: MIT + file LICENSE
Encoding: UTF-8
LazyData: true
Roxygen: list(markdown=TRUE)
RoxygenNote: 7.2.3
URL: https://github.com/amandaforde/mr.simss
BugReports: https://github.com/amandaforde/mr.simss/issues
Imports:
dplyr,
doParallel,
foreach,
magrittr,
mr.raps,
stats,
parallel,
pracma,
tibble,
TwoSampleMR,
abind
Remotes:
MRCIEU/TwoSampleMR
Suggests:
knitr,
rmarkdown
VignetteBuilder: knitr