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DESCRIPTION
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DESCRIPTION
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Package: simPRS
Type: Package
Title: Fast Simulation of Polygenic Risk Scores
Version: 0.9
Date: 2018-10-11
Authors@R: person( "Andrey A", "Shabalin",
role = c("aut", "cre"),
email = "andrey.shabalin@gmail.com",
comment = c(ORCID = "0000-0003-0309-6821"))
Description: Simulation of Polygenic Risk Score calculations allows to
(1) Select an optimal p-value threshold,
(2) Perform power analyses, and
(3) Estimate polygenicity of a phenotype.
Simulations are performed without direct simulations of the
genotype and phenotype data.
Instead, genome-wide association study (GWAS) summary statistics
are generated directly from their finite sample distributions.
License: LGPL-3
LazyLoad: yes
BugReports: https://github.com/andreyshabalin/simPRS/issues
URL: https://github.com/andreyshabalin/simPRS, https://andreyshabalin.shinyapps.io/simPRS/
Depends: R (>= 3.4.0), utils, graphics, stats, parallel
Suggests: knitr, rmarkdown
VignetteBuilder: knitr