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We've been testing diamond blastp v.2.1.8 and finding cases where the same inputs and parameters are producing non-deterministic alignment output. Could you take a look at some example files we have been working with?
https://ftp.ncbi.nlm.nih.gov/pub/murphyte/diamond_test/
example_1_cmd and example_1* output files show a small test case.
example_2_cmd and example_2* output files show larger test cases more similar to what we are working with in our pipeline.
Default parameters appear to be producing deterministic output with our queries/db. Of our added parameters, we believe specifying --masking 0 --very-sensitive together may be the culprit.
Thanks.
The text was updated successfully, but these errors were encountered:
Hello,
We've been testing diamond blastp v.2.1.8 and finding cases where the same inputs and parameters are producing non-deterministic alignment output. Could you take a look at some example files we have been working with?
https://ftp.ncbi.nlm.nih.gov/pub/murphyte/diamond_test/
example_1_cmd and example_1* output files show a small test case.
example_2_cmd and example_2* output files show larger test cases more similar to what we are working with in our pipeline.
Default parameters appear to be producing deterministic output with our queries/db. Of our added parameters, we believe specifying
--masking 0 --very-sensitive
together may be the culprit.Thanks.
The text was updated successfully, but these errors were encountered: