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There are many possible solutions. One would be to break the GC adjustment into smaller bins and weight the read count on those bins rather than making an adjustment per target.
In theory, this could happen when we have large exome targets as well, though this is probably seen most in WGS.
The text was updated successfully, but these errors were encountered:
@LeeTL1220 commented on Wed Jan 25 2017
There are many possible solutions. One would be to break the GC adjustment into smaller bins and weight the read count on those bins rather than making an adjustment per target.
In theory, this could happen when we have large exome targets as well, though this is probably seen most in WGS.
The text was updated successfully, but these errors were encountered: