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In the discussion in this branch #6351 (review) we were tripped up by the fact that the Carrot tests were showing a slight (between 5 and 7% on the aggregated $ time command output across 50 shards) runtime regression in the current version of HaplotypeCaller compared with a misconfigured older version of the tool. Specifically the faster older version was broadinstitute/gatk-nightly:2022-03-04-4.2.5.0-9-gb097f75c5-NIGHTLY-SNAPSHOT which was before the Java 17 migration (which is a high likelihood culprit form the past year).
Somebody should spend a few hours with a profiler to make sure there isn't some obvious culprit.
And a shard where a significant slowdown was observed spanned the region chr3:55313816 -> chr3:113699078 which should hopefully provide a good starting point for anybody investigating this.
The text was updated successfully, but these errors were encountered:
In the discussion in this branch #6351 (review) we were tripped up by the fact that the Carrot tests were showing a slight (between 5 and 7% on the aggregated
$ time
command output across 50 shards) runtime regression in the current version of HaplotypeCaller compared with a misconfigured older version of the tool. Specifically the faster older version was broadinstitute/gatk-nightly:2022-03-04-4.2.5.0-9-gb097f75c5-NIGHTLY-SNAPSHOT which was before the Java 17 migration (which is a high likelihood culprit form the past year).Somebody should spend a few hours with a profiler to make sure there isn't some obvious culprit.
Here is the command that Carrot was running:
And a shard where a significant slowdown was observed spanned the region
chr3:55313816
->chr3:113699078
which should hopefully provide a good starting point for anybody investigating this.The text was updated successfully, but these errors were encountered: