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name eracommons position piinfo
Nathan C. Sheffield
NSHEFF
Assistant Professor
true

\begin{education} Brigham Young University, Provo, UT & B.S & 04/2008 & Bioinformatics \ Duke University, Durham, NC & Ph.D. & 05/2013 & Bioinformatics and Computational Biology \ Center for Molecular Medicine, Vienna, Austria & Postdoctoral & 12/2015 & Computational Epigenomics \ Stanford University, Stanford, CA & Postdoctoral & 08/2016 & Computational Epigenomics \ \end{education}

A. Personal Statement

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B. Positions and Honors

Positions and Employment

  • 2016-pres. Assistant Professor, Center for Public Health Genomics, University of Virginia
  • 2016-pres. Assistant Professor, Department of Biomedical Engineering, University of Virginia

Honors and Awards

  • 2014 EMBO Long-term Postdoctoral Fellowship, European Molecular Biology Organization
  • 2014 HFSP Long-term Postdoctoral Fellowship, Human Frontier Science Program

C. Contributions to Science

H-index: 18. ORCID: 0000-0001-5643-4068. Links and citation info: My NCBI or www.databio.org.

  • Sheffield NC, Pierron G, Klughammer J, Datlinger P, Schönegger A, Schuster M, Hadler J, Surdez D, Guillemot D, Lapouble E, Freneaux P, Champigneulle J, Bouvier R, Walder D, Ambros IM, Hutter C, Sorz E, Amaral AT, de Álava E, Schallmoser K, Strunk D, Rinner B, Liegl-Atzwanger B, Huppertz B, Leithner A, de Pinieux G, Terrier P, Laurence V, Michon J, Ladenstein R, Holter W, Windhager R, Dirksen U, Ambros PF, Delattre O, Kovar H, Bock C, and Tomazou EM. DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma. 2017. Nat. Med 23: 386--395. DOI:10.1038/nm.4273
  • Sheffield NC, and Bock C. LOLA: enrichment analysis for genomic region sets and regulatory elements in R and Bioconductor. 2016. Bioinformatics 32: 587--589. PMCID:PMC4743627 DOI:10.1093/bioinformatics/btv612
  • Kovar H, Amatruda J, Brunet E, Burdach S, Cidre-Aranaz F, de Alva E, Dirksen U, van der Ent W, Grohar P, Grunewald TG, Helman L, Houghton P, Iljin K, Korsching E, Ladanyi M, Lawlor E, Lessnick S, Ludwig J, Meltzer P, Metzler M, Mora J, Moriggl R, Nakamura T, Papamarkou T, Sarikas BR, Redini F, Richter GH, Rossig C, Schadler K, Schafer BW, Scotlandi K, Sheffield NC, Shelat A, Snaar-Jagalska E, Sorensen P, Stegmaier K, Stewart E, Sweet-Cordero A, Szuhai K, Tirado OM, Tirode F, Toretsky J, Tsafou K, Uren A, Zinovyev A, and Delattre O. The second European interdisciplinary Ewing sarcoma research summit - A joint effort to deconstructing the multiple layers of a complex disease. 2016. Oncotarget. PMCID:PMC4890991 DOI:10.18632/oncotarget.6937
  • Tomazou EM, Sheffield NC, Schmidl C, Schuster M, Schönegger A, Datlinger P, Kubicek S, Bock C, and Kovar H. Epigenome mapping reveals distinct modes of gene regulation and widespread enhancer reprogramming by the oncogenic fusion protein EWS-FLI1. 2015. Cell Reports 10: 1082--1095. PMCID:PMC4542316 DOI:10.1016/j.celrep.2015.01.042

D. Research Support

Active

UVA start-up funds (PI:Sheffield) \tab8/23/2016-no end date
University of Virginia
Title: New faculty start-up funds from the University of Virginia
Role: PI

4-VA at UVA Collaborative (PI:Sheffield) \tab06/01/2018-05/31/2019
4-VA program
Title: A standardized database format for genomic locus enrichment analysis
Role: PI