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Correction factors are removed, not valid for any new created resolution #924

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rikrdo89 opened this issue Jan 29, 2025 · 0 comments
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@rikrdo89
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When starting with a .hic file which contains KR, VR, and VR_SQRT corrections and I want to convert it to an .mcool with the KR correction in the "weight" column, I use the following steps:

  1. Convert hic to cool
    hicConvertFormat -m "$myHic" --resolutions 5000 --inputFormat hic --outputFormat cool -o "${myHic/.hic/.cool}"

  2. Convert cool to mcool with KR correction
    hicConvertFormat -m ${myHic/.hic/.cool} --inputFormat cool --outputFormat mcool -o $name.KR.mcool --correction_name KR --resolutions 5000 10000 25000

However, the second step throws the error message:

INFO:hicexplorer.hicConvertFormat:Correction factors are removed. They are not valid for any new created resolution.

I did not find any additional information on the docs but would anyone be able to provide some insight on this error, and suggestions on how to approach the conversion of a .hic to .mcool with KR correction?

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