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Dragonfly

Dragonfly is a software package to analyze single particle diffractive imaging data. The package has the following parts

  • An implementation of the EMC single-particle reconstruction algorithm using MPI and OpenMP to merge diffraction patterns of approximately identical particles in random orientations.
  • Data stream simulator, that generates noisy single-particle diffraction patterns from a PDB file
  • An experimental pattern-classification GUI using some machine learning tools to separate single particle diffraction patterns in experimental data.

More detailed documentation can be found in the Wiki pages.

If you are in a hurry, just clone the repository and follow the Quick start instructions.

Please cite the following publication if you use Dragonfly for your work:

Ayyer, K., Lan, T. Y., Elser, V., & Loh, N. D. (2016). Dragonfly: an implementation of the expand–maximize–compress algorithm for single-particle imaging. Journal of applied crystallography, 49(4), 1320-1335.