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Put on the canvas following SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2c1cccc2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@@H](C(=O)O)NC(=O)CCCCCCCCCCCCCCCCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc4ccc(cc4)O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc5ccccc5)NC(=O)[C@H]([C@@H](C)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)C(C)(C)NC(=O)[C@H](Cc6cnc[nH]6)N
Press Add/Remove explicit hydrogens button to fold hydrogens
Actual behavior
System rise the spinner but it took too much time to got the result
Expected behavior
Folding hydrogens works same fast as unfold hydrogens.
Try it with following SMILES: C([H])([H])([H])C([H])([H])[C@@]([H])([C@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@]([H])(N([H])C([C@@]([H])(N([H])C(C([H])([H])N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C(C([H])([H])N([H])C([C@@]([H])(N([H])C(C(N([H])C([C@]([H])(N([H])[H])C([H])([H])c1[n]([H])c([H])nc1[H])=O)(C([H])([H])[H])C([H])([H])[H])=O)C([H])([H])C([H])([H])C(O[H])=O)=O)=O)[C@]([H])(O[H])C([H])([H])[H])=O)C([H])([H])c1c([H])c([H])c([H])c([H])c1[H])=O)[C@]([H])(O[H])C([H])([H])[H])=O)C([H])([H])O[H])=O)C([H])([H])C(O[H])=O)=O)C([H])(C([H])([H])[H])C([H])([H])[H])=O)C([H])([H])O[H])=O)C([H])([H])O[H])=O)C([H])([H])c1c([H])c([H])c(O[H])c([H])c1[H])=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=O)C([H])([H])C([H])([H])C(O[H])=O)=O)=O)C([H])([H])C([H])([H])C(N([H])[H])=O)=O)C([H])([H])[H])=O)C([H])([H])[H])=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N([H])C(C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N([H])C(C([H])([H])C([H])([H])[C@]([H])(N([H])C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(O[H])=O)=O)C(O[H])=O)=O)=O)=O)=O)C([H])([H])C([H])([H])C(O[H])=O)=O)C([H])([H])c1c([H])c([H])c([H])c([H])c1[H])=O)C(N([H])[C@]([H])(C(N([H])[C@@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])C([H])([H])C(N([H])[C@]([H])(C(N([H])C([H])([H])C(O[H])=O)=O)C([H])([H])C([H])([H])C([H])([H])N([H])/C(/N([H])[H])=N/[H])=O)=O)C([H])([H])C([H])([H])C([H])([H])N([H])/C(/N([H])[H])=N/[H])=O)C([H])(C([H])([H])[H])C([H])([H])[H])=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=O)C([H])([H])c1c2c([H])c([H])c([H])c([H])c2[n]([H])c1[H])=O)C([H])([H])[H])=O)C([H])([H])[H]
Ketcher version [e.g. v2.4.2].
Indigo Toolkit Version 1.18.0.0-g73c32dec3-wasm32-wasm-clang-12.0.0
Ketcher Version 2.19.0-rc.2 Build at 2024-03-11; 12:30:30
Chrome Version Version 122.0.6261.112 (Official Build) (64-bit)
Steps to Reproduce
CC[C@H](C)[C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2c1cccc2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@@H](C(=O)O)NC(=O)CCCCCCCCCCCCCCCCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc4ccc(cc4)O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc5ccccc5)NC(=O)[C@H]([C@@H](C)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)C(C)(C)NC(=O)[C@H](Cc6cnc[nH]6)N
Actual behavior
System rise the spinner but it took too much time to got the result
Expected behavior
Folding hydrogens works same fast as unfold hydrogens.
Try it with following SMILES:
C([H])([H])([H])C([H])([H])[C@@]([H])([C@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@]([H])(N([H])C([C@@]([H])(N([H])C(C([H])([H])N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C([C@@]([H])(N([H])C(C([H])([H])N([H])C([C@@]([H])(N([H])C(C(N([H])C([C@]([H])(N([H])[H])C([H])([H])c1[n]([H])c([H])nc1[H])=O)(C([H])([H])[H])C([H])([H])[H])=O)C([H])([H])C([H])([H])C(O[H])=O)=O)=O)[C@]([H])(O[H])C([H])([H])[H])=O)C([H])([H])c1c([H])c([H])c([H])c([H])c1[H])=O)[C@]([H])(O[H])C([H])([H])[H])=O)C([H])([H])O[H])=O)C([H])([H])C(O[H])=O)=O)C([H])(C([H])([H])[H])C([H])([H])[H])=O)C([H])([H])O[H])=O)C([H])([H])O[H])=O)C([H])([H])c1c([H])c([H])c(O[H])c([H])c1[H])=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=O)C([H])([H])C([H])([H])C(O[H])=O)=O)=O)C([H])([H])C([H])([H])C(N([H])[H])=O)=O)C([H])([H])[H])=O)C([H])([H])[H])=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N([H])C(C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N([H])C(C([H])([H])C([H])([H])[C@]([H])(N([H])C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(O[H])=O)=O)C(O[H])=O)=O)=O)=O)=O)C([H])([H])C([H])([H])C(O[H])=O)=O)C([H])([H])c1c([H])c([H])c([H])c([H])c1[H])=O)C(N([H])[C@]([H])(C(N([H])[C@@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])C([H])([H])C(N([H])[C@]([H])(C(N([H])C([H])([H])C(O[H])=O)=O)C([H])([H])C([H])([H])C([H])([H])N([H])/C(/N([H])[H])=N/[H])=O)=O)C([H])([H])C([H])([H])C([H])([H])N([H])/C(/N([H])[H])=N/[H])=O)C([H])(C([H])([H])[H])C([H])([H])[H])=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=O)C([H])([H])c1c2c([H])c([H])c([H])c([H])c2[n]([H])c1[H])=O)C([H])([H])[H])=O)C([H])([H])[H]
Ketcher version [e.g. v2.4.2].
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