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PTN000320364 #4695

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ValWood opened this issue Aug 10, 2023 · 4 comments
Closed

PTN000320364 #4695

ValWood opened this issue Aug 10, 2023 · 4 comments
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@ValWood
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ValWood commented Aug 10, 2023

  • PTHR ID & PTN node:
GO:0030050 vesicle transport along actin filament IBA with MGI:106612 , myo52 , 3143 , Q9Y4I1 , S000005853 , PTN000320364

GO:0030050
vesicle transport along actin filament
IBA with MGI:106612 , myo52 , 3143 , Q9Y4I1 , S000005853 , PTN000320364

  • Sequences with problematic annotation (ID + gene/protein name):

https://www.pombase.org/gene/SPBC146.13c
(I think the process of transport along actin filament might be for type V and/or Type V myosisns. This is a type I myosine which in pombe is restricted to endocytosis and does not have this role.

  • Type of Issue: Erroneous source or erroneous propagation, or other issue

Propagation?

  • Add the label 'high priority' if needed. Generally high priority issues affect a lot of proteins, and annotations are incorrect (as opposed to just imprecise).
@ValWood
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ValWood commented Aug 10, 2023

Actually type one myosin also has a role in fission yeast used in oscillatoy movement of the nucleus, but as far as I'm aware, it doesn't have any role in the transport of vesicles along actin

@ValWood
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ValWood commented Aug 11, 2023

ignore!

@ValWood ValWood closed this as completed Aug 11, 2023
@ValWood
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ValWood commented Aug 11, 2023

Although I would question this association:

GO:0031982 vesicle IBA with PTN000320364 , O43795 , MGI:105976 , Q29122 , DDB_G0289117 , DDB_G0272112 , FBgn0011225 , Q12965 , Q9UM54 , Q9LHE9 , 1560646 , Q9I8D1 , F1PRN2 , S000005853 , DDB_G0274575 , 621347 , MGI:104785 , Q9Y4I1 , MGI:104510 , DDB_G0288679 , MGI:106612 , 3143 , locus:2149932 , 621321

GO:0031982
vesicle
IBA with PTN000320364 , O43795 , MGI:105976 , Q29122 , DDB_G0289117 , DDB_G0272112 , FBgn0011225 , Q12965 , Q9UM54 , Q9LHE9 , 1560646 , Q9I8D1 , F1PRN2 , S000005853 , DDB_G0274575 , 621347 , MGI:104785 , Q9Y4I1 , MGI:104510 , DDB_G0288679 , MGI:106612 , 3143 , locus:2149932 , 621321

Because although the myosin associates with the endosome, it isn't part of it?

@ValWood ValWood reopened this Aug 11, 2023
@marcfeuermann
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A huge family. I've removed annotations to the root and re-annotated the family.

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