Entner-Doudoroff pathway

[ValWood]

CHatGPT
Conclusion:
While both pathways involve the metabolism of glucose or glucose-related molecules, the gluconate pathway is not the same as the Entner-Doudoroff pathway. The gluconate pathway focuses on the utilization of gluconate, while the ED pathway breaks down glucose directly. There is some overlap in the intermediates involved, but the pathways differ in their overall reactions and the organisms that use them.

GO has
GO:0061678 Entner-Doudoroff pathway 9,871 annotations
GO:0061679 Entner-Doudoroff pathway through gluconate
GO:0061688 glycolytic process via Entner-Doudoroff Pathway 318 annotations
GO:0009255 Entner-Doudoroff pathway through 6-phosphogluconate 9,871 annotations
GO:0061680 Entner-Doudoroff pathway through gluconate to D-glyceraldehyde
GO:0061681 Entner-Doudoroff pathway through gluconate to D-glyceraldehyde-3-phosphate

GO:0061679 Entner-Doudoroff pathway through gluconate
"gluconate pathway
is
gluconate pathway | related

but should't this be called gluconate pathway?

I ask because pombe has a glucontae pathway, and we have used "glycolytic process via Entner-Doudoroff Pathway"
but yeast do not appear to have Entner-Doudoroff pathway

[ValWood]

https://en.wikipedia.org/wiki/Entner%E2%80%93Doudoroff_pathway
wikepedia says
The Entner–Doudoroff pathway (ED Pathway) is a metabolic pathway that is most notable in Gram-negative bacteria, certain Gram-positive bacteria and archaea.[1]

Yeast have only need engineered to do this s"To express the ED pathway in yeast, you need to express two additional enzymes: 6-phosphogluconate dehydratase (PGDH) and KDPG aldolase.
KDPG aldolase from Escherichia coli can be expressed in yeast cytosol."

I think we can begin with taxon restrictions on these pathways, but I also wonder why we have so many terms?

[ValWood]

These appear to be intermediates based on the Wikipedia page.
Propose
merge all
add taxon restrictions and
create a new term for gluconate pathway

(needs reviewing to metacyc, but at first glance this seems correct)

[ValWood]

might be relevant
#28392

[sjm41]

@ukemi @deustp01 @rozaru

[ValWood]

It seems that minimally we can apply a taxon restrictions for eukaryotes, but I would still require "gluconate pathway"