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Autogating #22

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alliecreason opened this issue Jul 5, 2022 · 1 comment

Contributor

alliecreason commented Jul 5, 2022

Current autogating approaches in scimap work when markers are well represented but not for low abundance cell populations.

Explore strategies for autogating

iterative clipping
alternative gmm mixture models (example from mcmicro)
testing for bimodal distribution

Needed for

marker positivity
phenotyping

Contributor Author

alliecreason commented Jul 13, 2022

Also RESTORE: https://gitlab.com/Chang_Lab/cycif_int_norm/-/tree/master/python_code.

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