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Common Disease Network |
We have developed a web application that allows interactive exploration of a network of common diseases. The edges between the common diseases are based on similarity of the phenotypic profiles of the two diseases. If the similarity exceeds a threshold, we draw an edge, otherwise not. The similarity is calculated using the Human Phenotype Ontology.
The application is available at http://compbio.charite.de/CDN/cdn.html
The paper for this project is:
Groza, T., Kohler, S., Moldenhauer, D., Vasilevsky, N., Baynam, G., Zemojtel, T., Schriml, L. M., Kibbe, W. A., Schofield, P. N., Beck, T., et al. (2015). The Human Phenotype Ontology: Semantic Unification of Common and Rare Disease. The American Journal of Human Genetics, Link
If you have further questions contact: dr.sebastian.koehler@gmail.com