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library.bib
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Automatically generated by Mendeley Desktop 1.19.4
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@article{Rothan2020,
author = {Rothan, Hussin A. and Byrareddy, Siddappa N.},
doi = {10.1016/j.jaut.2020.102433},
file = {:Users/juandp77/Dropbox/references/Journal of Autoimmunity/The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak - Rothan, Byrareddy - 2020.pdf:pdf},
journal = {Journal of Autoimmunity},
pages = {102433},
title = {{The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak}},
volume = {109},
year = {2020}
}
@article{Ziu2020,
author = {Ziu, Mateo and van den Bent, Martin J and Strowd, Roy and Shih, Helen A and Schiff, David and Olar, Adriana and Ney, Douglas E and Lassman, Andrew B and Hottinger, Andreas F and Gatson, Na Tosha N and Blakeley, Jaishri O and Mohile, Nimish A},
doi = {10.1093/neuonc/noaa090},
file = {:Users/juandp77/Dropbox/references/Neuro-Oncology/Urgent considerations for the neuro-oncologic treatment of patients with gliomas during the COVID-19 pandemic - Ziu et al. - 2020.pdf:pdf},
journal = {Neuro-Oncology},
number = {7},
pages = {912--917},
title = {{Urgent considerations for the neuro-oncologic treatment of patients with gliomas during the COVID-19 pandemic}},
volume = {22},
year = {2020}
}
@article{Hulou2015,
abstract = {G ross-total resection (GTR) of intrinsic low-grade gliomas (LGG) in the brain is often difficult given their infiltrative nature and the risk of neurologi-cal morbidity. 1,12,14 Current data on the value of surgical treatment is mostly based on observational studies. 12 Con-sequently, the goal of maximum resection in patients with minimal symptoms remains controversial, despite the fact that those studies show improved overall survival (OS) after GTR. 1,15 Recently, a population-based parallel cohort study conducted in Norway provided very good evidence of improved survival for patients with LGG treated us-ing early surgery as opposed to watchful waiting, the best evidence so far arguing for the former approach. 3 Never-theless, it has been argued that any incremental survival advantage in patients treated with GTR is simply a self-fulfilling prophecy of selection bias. 12 Recent advances in our histopathological, molecular, and genetic under-standing of LGG, however, have prompted more nuanced management strategies. Several significant demographic, clinical, and pathological prognostic factors that can aid the treatment team regarding the use of postoperative ad-juvant therapy have been reported. 2 Advanced age, larger tumor volume, subtotal resection, and diffuse astrocytoma subtype have been found to be associated with unfavor-able outcomes, and additional therapy has had a beneficial effect in patients with these features. 9,10 Recent advances in the molecular and genetic profiling of LGG have result-ed in more accurate survival predictions, which has neces-sitated a thorough examination of the utility of adjuvant therapy after subtotal resection (STR). 6 adjuvant chemotherapy In this issue of Neurosurgical Focus, Nitta et al. pro-vide a treatment strategy for LGG based on extent of re-section with an emphasis on two WHO Grade II subtypes: diffuse astrocytoma and oligodendroglial tumors. Utiliz-ing results from their retrospective cohort study, these au-thors highlight the predictors of OS and progression-free survival (PFS). 9 In both LGG subsets, radiotherapy (RT) did not clearly correlate with an OS or PFS advantage. Al-ternatively, adjuvant chemotherapy with nimustine hydro-chloride (ACNU) and vincristine after STR was strongly associated with increased PFS in the oligodendroglial subtype, but did not confer either an OS or a PFS advan-tage in patients with a diffuse astrocytoma subtype. These findings suggest that the adjuvant treatment of choice in patients with low-grade oligodendroglioma is chemother-apy and possibly repeat surgery in those with low-grade diffuse astrocytoma. However, chemotherapy resulted in a poorer prognosis in oligodendroglioma patients with wild-type IDH1 and prolonged PFS in patients with IDH1 mu-tation and/or 1p/19q codeletion. Overall survival, but not PFS, was found to be significantly associated with IDH1 status, and repeat surgery was suggested for patients with wild-type IDH1 regardless of the histopathological diag-nosis. adjuvant rt The role of surgery, extent of resection, and RT in the long-term outcome for patients with LGGs remains ir-resolute given the paucity of Level 1 data that addresses quality of life and/or OS in both symptomatic and inci-dental LGGs. 4,14 The European Organisation for Research and Treatment of Cancer (EORTC) 22845 trial, which looked at the long-term efficacy of early versus delayed RT in adults with LGG, was an attempt to determine the role of adjuvant RT. Trial researchers found statistically significant improvement in PFS in the early-irradiated group. Salvage chemotherapy was also administered to 37{\%} of the irradiated patients who had demonstrated clinical or radiographic recurrence.},
author = {Hulou, M Maher and Chiocca, E Antonio},
doi = {10.3171/2014.10.FOCUS14651.include},
file = {:Users/juandp77/Dropbox/references/Neurosurgical focus/The management of low-grade glioma in adults - Hulou, Chiocca - 2015.pdf:pdf},
issn = {10920684},
journal = {Neurosurgical focus},
number = {1},
pages = {E8},
title = {{The management of low-grade glioma in adults}},
volume = {38},
year = {2015}
}
@article{Duffau2013,
abstract = {Background and purpose: Surgery for diffuse low-grade glioma (DLGG) was debated for a long time. Discrepancies in the classical literature are mainly due to the lack of objective radiological assessment of the extent of resection (EOR). Here, the goal is to review the recent data on oncological and functional outcomes. Methods: Surgical series with calculation of EOR on postoperative MRI were reviewed. Results: In all modern series, a more aggressive resection predicted significant improvement in overall survival (OS) compared with a simple debulking. Especially, an extended removal of a margin beyond the MRI-defined abnormalities (" supra-total" resection) significantly increased OS by delaying malignant transformation. Furthermore, advances in intraoperative brain mapping techniques resulted in a minimization of neurological deficits. Discussion/Conclusion: These recent data strongly argue in favor of achieving a maximal resection of DLGG as the first therapeutic option. Biopsy should be considered only in very diffuse lesions (gliomatosis) or when a subtotal resection is not a priori possible. Thus, neurosurgeons should change their mind, by operating the brain involved by a chronic tumoral disease rather than by trying to remove a "tumor mass" The aim is not to achieve a simple "tumorectomy", but the most extensive resection of the brain invaded by DLGG, on the condition that this part of the brain is not crucial for cerebral functions. This new philosophy suggests to perform early and maximal resection according to functional (and not purely oncological or anatomical) boundaries in awake patients. This perspective is the best way to build a personalized "functional surgical neuro-oncology". ?? 2012 Elsevier Masson SAS.},
author = {Duffau, H.},
doi = {10.1016/j.neuchi.2012.11.001},
file = {:Users/juandp77/Dropbox/references/Neurochirurgie/A new philosophy in surgery for diffuse low-grade glioma (DLGG) Oncological and functional outcomes - Duffau - 2013.pdf:pdf},
isbn = {0028-3770},
issn = {00283770},
journal = {Neurochirurgie},
keywords = {Awake surgery,Diffuse low-grade gliomas,Extent of resection,Functional mapping,Overall survival,Supra-total resection},
number = {1},
pages = {2--8},
pmid = {23410764},
publisher = {Elsevier Masson SAS},
title = {{A new philosophy in surgery for diffuse low-grade glioma (DLGG): Oncological and functional outcomes}},
url = {http://dx.doi.org/10.1016/j.neuchi.2012.11.001},
volume = {59},
year = {2013}
}
@article{Brown2014,
abstract = {The conventional model of language-related brain structure describing the arcuate fasciculus as a key white matter tract providing a direct connection between Wernicke's region and Broca's area has been called into question. Specifically, the inferior precentral gyrus, possessing both primary motor (Brodmann Area [BA] 4) and premotor cortex (BA 6), has been identified as a potential alternative termination. The authors initially localized cortical sites involved in language using measurement of event-related gamma-activity on electrocorticography (ECoG). The authors then determined whether language-related sites of the temporal lobe were connected, via white matter structures, to the inferior frontal gyrus more tightly than to the precentral gyrus. The authors found that language-related sites of the temporal lobe were far more likely to be directly connected to the inferior precentral gyrus through the arcuate fasciculus. Furthermore, tractography was a significant predictor of frontal language-related ECoG findings. Analysis of an interaction between anatomy and tractography in this model revealed tractrography to have the highest predictive value for language-related ECoG findings of the precentral gyrus. This study failed to support the conventional model of language-related brain structure. More feasible models should include the inferior precentral gyrus as a termination of the arcuate fasciculus. The exact functional significance of direct connectivity between temporal language-related sites and the precentral gyrus requires further study.},
archivePrefix = {arXiv},
arxivId = {NIHMS150003},
author = {Brown, Erik C. and Jeong, Jeong Won and Muzik, Otto and Rothermel, Robert and Matsuzaki, Naoyuki and Juh{\'{a}}sz, Csaba and Sood, Sandeep and Asano, Eishi},
doi = {10.1002/hbm.22331},
eprint = {NIHMS150003},
file = {:Users/juandp77/Dropbox/references/Human Brain Mapping/Evaluating the arcuate fasciculus with combined diffusion-weighted MRI tractography and electrocorticography - Brown et al. - 2014.pdf:pdf},
isbn = {1097-0193},
issn = {10970193},
journal = {Human Brain Mapping},
keywords = {Connectivity,DTI,Event-related augmentation of gamma-activity,High-frequency oscillations (HFOs),Naming,Ripples,Speech,Tractography},
number = {5},
pages = {2333--2347},
pmid = {23982893},
title = {{Evaluating the arcuate fasciculus with combined diffusion-weighted MRI tractography and electrocorticography}},
volume = {35},
year = {2014}
}
@article{Blattert2019,
abstract = {While electronic prescribing (e-prescribing) systems with drug interaction and allergy alerts promise to improve medication safety in ambulatory care, clinicians often override these safety features. We undertook a study of respondents' satisfaction with e-prescribing systems, their perceptions of alerts, and their perceptions of behavior changes resulting from alerts.},
author = {Blattert, T. R. and Schnake, K. J. and Gonschorek, O. and Katscher, S. and Ullrich, B. W. and Gercek, E. and Hartmann, F. and M{\"{o}}rk, S. and Morrison, R. and M{\"{u}}ller, M. L. and Partenheimer, A. and Piltz, S. and Scherer, M. A. and Verheyden, A. and Zimmermann, V.},
doi = {10.1007/s00132-018-03666-6},
file = {:Users/juandp77/Dropbox/references/Orthopade/Nonsurgical and surgical management of osteoporotic vertebral body fractures Recommendations of the Spine Section of the German Society.pdf:pdf},
issn = {00854530},
journal = {Orthopade},
keywords = {Classification,Expert opinion,Osteoporotic fractures,Score,Spine},
number = {1},
pages = {84--91},
title = {{Nonsurgical and surgical management of osteoporotic vertebral body fractures: Recommendations of the Spine Section of the German Society for Orthopaedics and Trauma (DGOU)}},
volume = {48},
year = {2019}
}
@misc{Quigley1984a,
abstract = {A case of familial anterior sacral meningocele associated with a dermoid tumor is reported. This patient presented with recurrent aseptic meningitis. The role of computerized tomography following metrizamide myelography in the diagnosis of this lesion is discussed.},
author = {Quigley, M R and Schinco, F and Brown, J T},
booktitle = {Journal of neurosurgery},
doi = {10.3171/jns.1984.61.4.0790},
issn = {0022-3085},
number = {4},
pages = {790--792},
pmid = {6470791},
title = {{Anterior sacral meningocele with an unusual presentation. Case report.}},
volume = {61},
year = {1984}
}
@article{Ma2018,
abstract = {STUDY DESIGN A retrospective cohort study. OBJECTIVE To investigate the relationship between spinal cord microstructures and spinal cord dysfunction in degenerative cervical myelopathy (DCM) patients, a follow-up study was carried out using diffusion tensor imaging (DTI) and neurite orientation dispersion and density imaging (NODDI), an advanced diffusion model. SUMMARY OF BACKGROUND DATA DTI has been used for diagnosis of DCM. Though DTI has advantages of high sensitivity and quantitative features, it is limited by its low specificity for measuring microstructures. METHODS 58 postoperative DCM patients with 12-14 months of surgical recovery were recruited, as well as 14 healthy volunteers for control group. All DTI and NODDI metrics were measured at the most stenotic levels of patients and at all levels of control group. A t-test was used to compare the metrics between patient and control groups, and Spearman's correlation was used to test the relationship between the metrics and clinical assessment, modified Japanese Orthopedic Association (mJOA) scores. RESULTS T-test showed that DTI metrics, neurite density Vic, and free water fraction Viso had significant differences between control group and the most stenotic levels in patients. For DTI metrics, fractional anisotropy (FA), radial diffusivity (RD) and mean diffusivity (MD) in patients were significantly correlated with mJOA. For NODDI metrics, only Vic is positively correlated with mJOA. CONCLUSIONS The results of t-test and correlation with mJOA suggest that DTI and NODDI are valuable for evaluating spinal cord function. Results of NODDI indicate that the reason for FA reduction in DCM may be decreased neurite density, not increased orientation dispersion. LEVEL OF EVIDENCE 3.},
author = {Ma, Xiaodong and Han, Xiao and Jiang, Wen and Wang, Jinchao and Zhang, Zhe and Li, Guangqi and Zhang, Jieying and Cheng, Xiaoguang and Chen, Huijun and Guo, Hua and Tian, Wei},
doi = {10.1097/BRS.0000000000002541},
file = {:Users/juandp77/Dropbox/references/Spine/A Follow-up Study of Postoperative DCM Patients Using Diffusion MRI with DTI and NODDI - Ma et al. - 2018.pdf:pdf},
isbn = {0000000000},
issn = {0362-2436},
journal = {Spine},
pages = {1},
pmid = {29300252},
title = {{A Follow-up Study of Postoperative DCM Patients Using Diffusion MRI with DTI and NODDI}},
url = {http://insights.ovid.com/crossref?an=00007632-900000000-95239},
year = {2018}
}
@article{Koreckij2015,
abstract = {Degenerative spondylolisthesis (DS) is one of the more commonly encountered spine conditions. The diagnosis of DS has changed little in the last 30 years. However, there has been an evolution in the treatment of this disease entity. There have been several landmark papers that helped govern our treatment. These helped serve as the basis for the treatment arms of the Spine Patient Outcomes Research Trial (SPORT), which offers the highest quality evidence to date. Although few would argue that the fusion of the diseased segment appears to offer the best and most durable results, treatment of this disease is best tailored to the individual. Fusion may offer the best results in the young active patient, but the same results may never become evident in the medically infirm patient. Laminectomy or unilateral laminoforaminotomy still plays a role in disease treatment. This review will focus on the diagnosis and the treatment of DS as well as discuss the author's preferred treatment of this disease.},
author = {Koreckij, Theodore D and Fischgrund, Jeffrey S},
doi = {10.1097/BSD.0000000000000298},
file = {:Users/juandp77/Dropbox/references/Journal of spinal disorders {\&} techniques/Degenerative Spondylolisthesis. - Koreckij, Fischgrund - 2015.pdf:pdf},
issn = {1539-2465 (Electronic)},
journal = {Journal of spinal disorders {\&} techniques},
number = {7},
pages = {236--241},
pmid = {26172828},
title = {{Degenerative Spondylolisthesis.}},
volume = {28},
year = {2015}
}
@article{Novegno2011,
abstract = {Posterior quadrant dysplasia (PQD) is a rare variant of cortical dysplasia involving the posterior regions of a single hemisphere. It is always associated with early onset, refractory epilepsy often characterized by a "catastrophic" evolution. The experience on its surgical management during the first year of life is limited to sporadic, isolated cases. Between 2002 and 2005, four children less than one-year-old and affected by drug-resistant epilepsy associated with PQD were admitted to our Institution and underwent surgical treatment. One patient remained seizure-free during all the follow-up (Engel I). The remaining three children showed a recurrence of the seizures, requiring subsequent surgical procedures in two cases. In one case (Engel II), the seizure control has been obtained thanks to pharmacological treatment. The other two patients respectively had only a partial (Engel III) and a less relevant reduction of the number of seizures (Engel IV). Both the epileptic and the neuropsychological outcome of our series were significantly influenced by persistent contralateral interictal anomalies rather than by the timing of the surgical procedure. Unpredictable results should be expected in this kind of patients if there is the detection of contralateral independent epileptiform activities on the EEG at diagnosis. Parents and relatives should be aware of the results' variability, even though a reduction of seizures may be expected, enabling an easier handling of the child's condition. ?? 2010 British Epilepsy Association.},
author = {Novegno, F. and Massimi, L. and Chieffo, D. and Battaglia, D. and Frassanito, P. and Bianco, L. F. and Tartaglione, T. and Tamburrini, G. and {Di Rocco}, C. and Guzzetta, F.},
doi = {10.1016/j.seizure.2010.09.015},
file = {:Users/juandp77/Dropbox/references/Seizure/Epilepsy surgery of posterior quadrant dysplasia in the first year of life Experience of a single Centre with long term follow-up - Nove.pdf:pdf},
issn = {10591311},
journal = {Seizure},
keywords = {Cognitive delay,Drug-resistant epilepsy,Hemi-hemimegalencephaly infancy,Posterior quadrant dysplasia,Surgery},
number = {1},
pages = {27--33},
pmid = {20951066},
publisher = {BEA Trading Ltd},
title = {{Epilepsy surgery of posterior quadrant dysplasia in the first year of life: Experience of a single Centre with long term follow-up}},
volume = {20},
year = {2011}
}
@article{Salmenpera2001,
abstract = {Patients with drug-refractory temporal lobe epilepsy (TLE) often have hippocampal and amygdaloid damage. The present study investigated the factors associated with the occurrence and severity of damage in patients with partial epilepsy. Magnetic resonance imaging was used to measure the volumes of the hippocampus and the amygdala in 241 patients with different durations of epilepsy. We also investigated the association of damage with the location of seizure focus and clinical factors (age at onset of seizures, lifetime seizure number and medical history of complex febrile convulsions, intracranial infection or status epilepticus) with regression analysis. We found that high lifetime seizure number (P{\textless}0.05), history of complex febrile convulsions (P{\textless}0.01), and age ≤5 years at the time of the first seizure (P{\textless}0.01) were significant risk factors for reduced hippocampal volume in TLE patients. The severity of amygdaloid damage did not differ between TLE patients with different durations of epilepsy or seizure frequency, but complex febrile convulsions (P{\textless}0.05) and intracranial infection (P{\textless}0.05) were associated with amygdaloid damage. In patients with extratemporal or unclassified partial epilepsy, the hippocampal and amygdaloid volumes did not differ when patients with different durations of epilepsy were compared with controls. The present findings indicate that a high seizure number, the occurrence of complex febrile convulsions, and an early onset of seizures contribute to hippocampal volume reduction in patients with TLE. The data provided have important implications with regard to early and effective management and seizure control in vulnerable patients. {\textcopyright} 2001 Published by Elsevier Science B.V.},
author = {Salmenper{\"{a}}, Tuuli and K{\"{a}}lvi{\"{a}}inen, Reetta and Partanen, Kaarina and Pitk{\"{a}}nen, Asla},
doi = {10.1016/S0920-1211(01)00258-3},
file = {:Users/juandp77/Dropbox/references/Epilepsy Research/Hippocampal and amygdaloid damage in partial epilepsy A cross-sectional MRI study of 241 patients - Salmenper{\"{a}} et al. - 2001.pdf:pdf},
issn = {09201211},
journal = {Epilepsy Research},
keywords = {Amygdala,Hippocampus,MRI volumetry,Seizure number,Temporal lobe epilepsy},
number = {1},
pages = {69--82},
pmid = {11395291},
title = {{Hippocampal and amygdaloid damage in partial epilepsy: A cross-sectional MRI study of 241 patients}},
volume = {46},
year = {2001}
}
@article{Owler2001,
abstract = {Five patients with hydrocephalus who failed to respond to apparently adequate CSF drainage via a functioning shunt (four cases) or external ventricular drain (one case) are described. In three of the four shunted cases, the shunt was ventriculo-peritoneal with a medium pressure valve, and in one a combination of peritoneal and atrial shunts both with low pressure valves. All five patients were tested for possible low pressure hydrocephalus by a period of external ventricular drainage at heights of 0 to – 5 cm H 2 O below the reference point (external auditory meatus — EAM). Four of the five patients showed rapid and significant clinical improvement and went on to shunt revision (three) or insertion (one). The shunts were then all peritoneal, of which three were valveless, whilst one had a Sophy programmable valve at the lowest setting. In all four patients the improvement was sustained and was associated with a radiological (CT or MRI) improvement which varied from marked to slight. In the fifth patient there was no improvement with low pressure external drainage and no shunt revision was undertaken. On the basis of these cases the possible entity of low pressure hydrocephalus is discussed with particular reference to mechanism, recognition and management.},
author = {Owler, B K and Jacobson, E E and Johnston, I H},
doi = {10.1080/0268869012007253},
file = {:Users/juandp77/Dropbox/references/British Journal of Neurosurgery/Low pressure hydrocephalus issues of diagnosis and treatment in five cases - Owler, Jacobson, Johnston - 2001.pdf:pdf},
issn = {0268–8697},
journal = {British Journal of Neurosurgery},
keywords = {Hydrocephalus,low pressure,valveless shunt},
number = {4},
pages = {353--359},
pmid = {11599454},
title = {{Low pressure hydrocephalus: issues of diagnosis and treatment in five cases}},
volume = {15},
year = {2001}
}
@article{Cohen-Gadol2003a,
abstract = {OBJECT: Spinal meningiomas occur most frequently in older patients. They are well-circumscribed and slow-growing tumors that are associated with good patient outcomes following surgery. Spinal meningiomas occurring in younger patients may be more aggressive, with a worse prognosis. The authors present their 21-year experience with spinal meningiomas in patients younger than 50 years of age.$\backslash$n$\backslash$nMETHODS: The authors reviewed data obtained in 40 patients (age {\textless} 50 years) treated at the Mayo Clinic, Rochester, during the past 21 years; in all cases the lesions were histologically confirmed spinal meningiomas. Five men (12.5{\%}) and 35 women (87.5{\%}) (mean age 34.5 +/- 10.9 years) underwent 52 operations for 41 tumors. The mean follow-up duration was 82 +/- 93 months (range 0-445 months). The data obtained in these patients were compared with those derived from a random control cohort of 40 patients older than age 50 years in whom spinal meningiomas were resected at the Mayo Clinic during a similar period. In this cohort, there were 33 women and seven men whose mean age was 67.1 +/- 9.5 years. The mean follow-up duration for the older group was 88 +/- 72.3 months (range 18-309 months). Compared with the random cohort of older patients, younger patients there tended to have more tumors located in the cervical spine (39{\%}) as well as a greater number of predisposing factors such as neurofibromatosis Type 2, radiation exposure, or trauma. Nine (22{\%}) of the patients younger than 50 years of age required reoperation for residual or recurrent tumor compared with two (5{\%}) in the older patient control group. The overall mortality rate at the completion of the study for the younger patients was 10{\%}.$\backslash$n$\backslash$nCONCLUSIONS: Spinal meningiomas in younger patients have a worse prognosis than similar tumors in older patients.},
author = {Cohen-Gadol, Aaron a and Zikel, Ofer M and Koch, Cody a and Scheithauer, Bernd W and Krauss, William E},
doi = {10.3171/spi.2003.98.3.0258},
isbn = {0022-3085},
issn = {0022-3085},
journal = {Journal of neurosurgery},
keywords = {Adolescent,Adult,Age Distribution,Age Factors,Aged,Aged, 80 and over,Child,Female,Humans,Laminectomy,Laminectomy: methods,Male,Meningioma,Meningioma: mortality,Meningioma: pathology,Meningioma: surgery,Middle Aged,Neoplasm Recurrence, Local,Neoplasm Staging,Postoperative Complications,Reoperation,Spinal Cord Neoplasms,Spinal Cord Neoplasms: mortality,Spinal Cord Neoplasms: pathology,Spinal Cord Neoplasms: surgery,Survival Analysis,Treatment Outcome},
number = {3 Suppl},
pages = {258--63},
pmid = {12691381},
title = {{Spinal meningiomas in patients younger than 50 years of age: a 21-year experience.}},
url = {http://www.ncbi.nlm.nih.gov/pubmed/12691381},
volume = {98},
year = {2003}
}
@article{Goto2006,
abstract = {OBJECT: The authors evaluated their surgical experience over 20 years with 14 treated falcotentorial meningiomas. METHODS: In the past 20 years, 14 patients with falcotentorial junction meningiomas were surgically treated. There were seven men and seven women, whose ages ranged from 34 to 79 years. On the basis of neuroimaging studies, the authors analyzed the influence of the anatomical relationship of the tumor to the vein of Galen, patency of the vein of Galen, tumor size, and the signal intensities on the magnetic resonance images to determine possible difficulties that might be encountered during surgery and to prognosticate the outcome of surgery. Depending on the relationship with the vein of Galen, tumors were labeled as either a superior or an inferior type. All tumors were resected via an occipital transtentorial approach. The surgical outcome in eight patients was excellent; in the remaining six patients, it was fair. Of the prognostic factors, tumor location especially seemed to be the most important (p {\textless} 0.01, Fisher exact test). The outcome associated with the inferior type of tumor was significantly less optimal probably due to the relationship to the deep veins and the brainstem. In this series, the occlusion of deep veins did not significantly influence outcome. CONCLUSIONS:. Classification of the tumor location by preoperative neuroimaging studies can be helpful in estimating the surgical difficulty that might be encountered in treating the falcotentorial junction meningioma.},
author = {Goto, Takeo and Ohata, Kenji and Morino, Michiharu and Takami, Toshihiro and Tsuyuguchi, Naohiro and Nishio, Akimasa and Hara, Mitsuhiro},
doi = {10.3171/jns.2006.104.1.47},
file = {:Users/juandp77/Dropbox/references/Journal of neurosurgery/Falcotentorial meningioma surgical outcome in 14 patients. - Goto et al. - 2006.pdf:pdf},
isbn = {0022-3085 (Print)},
issn = {0022-3085},
journal = {Journal of neurosurgery},
number = {1},
pages = {47--53},
pmid = {16509146},
title = {{Falcotentorial meningioma: surgical outcome in 14 patients.}},
volume = {104},
year = {2006}
}
@article{Claus2015a,
abstract = {Significant gaps exist in our understanding of the causes and clinical management of glioma. One of the biggest gaps is how best to manage low-grade (World Health Organization [WHO] Grade II) glioma. Low-grade glioma (LGG) is a uniformly fatal disease of young adults (mean age 41 years), with survival averaging approximately 7 years. Although LGG patients have better survival than patients with high-grade (WHO Grade III or IV) glioma, all LGGs eventually progress to high-grade glioma and death. Data from the Surveillance, Epidemiology and End Results (SEER) program of the National Cancer Institute suggest that for the majority of LGG patients, overall survival has not significantly improved over the past 3 decades, highlighting the need for intensified study of this tumor. Recently published research suggests that historically used clinical variables are not sufficient (and are likely inferior) prognostic and predictive indicators relative to information provided by recently discovered tumor markers (e.g., 1p/19q deletion and IDH1 or IDH2 mutation status), tumor expression profiles (e.g., the proneural profile) and/or constitutive genotype (e.g., rs55705857 on 8q24.21). Discovery of such tumor and constitutive variation may identify variables needed to improve randomization in clinical trials as well as identify patients more sensitive to current treatments and targets for improved treatment in the future. This article reports on survival trends for patients diagnosed with LGG within the United States from 1973 through 2011 and reviews the emerging role of tumor and constitutive genetics in refining risk stratification, defining targeted therapy, and improving survival for this group of relatively young patients.},
author = {Claus, Elizabeth B. and Walsh, Kyle M. and Wiencke, John K. and Molinaro, Annette M. and Wiemels, Joseph L. and Schildkraut, Joellen M. and Bondy, Melissa L. and Berger, Mitchel and Jenkins, Robert and Wrensch, Margaret},
doi = {10.3171/2014.10.FOCUS12367},
file = {:Users/juandp77/Dropbox/references/Neurosurgical Focus/Survival and low-grade glioma The emergence of genetic information - Claus et al. - 2015.pdf:pdf},
issn = {10920684},
journal = {Neurosurgical Focus},
keywords = {Epidemiology,GWAS,Genes,Glioma,Low grade,SEER,Survival,Treatment},
month = {jan},
number = {1},
pages = {E6},
title = {{Survival and low-grade glioma: The emergence of genetic information}},
url = {http://thejns.org/doi/abs/10.3171/2014.10.FOCUS12367 https://thejns.org/view/journals/neurosurg-focus/38/1/article-pE6.xml},
volume = {38},
year = {2015}
}
@article{Ghogawala2016a,
abstract = {BackgroundThe comparative effectiveness of performing instrumented (rigid pedicle screws affixed to titanium alloy rods) lumbar spinal fusion in addition to decompressive laminectomy in patients with symptomatic lumbar grade I degenerative spondylolisthesis with spinal stenosis is unknown. MethodsIn this randomized, controlled trial, we assigned patients, 50 to 80 years of age, who had stable degenerative spondylolisthesis (degree of spondylolisthesis, 3 to 14 mm) and symptomatic lumbar spinal stenosis to undergo either decompressive laminectomy alone (decompression-alone group) or laminectomy with posterolateral instrumented fusion (fusion group). The primary outcome measure was the change in the physical-component summary score of the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36; range, 0 to 100, with higher scores indicating better quality of life) 2 years after surgery. The secondary outcome measure was the score on the Oswestry Disability Index (range, 0 to 100, with higher scores i...},
author = {Ghogawala, Zoher and Dziura, James and Butler, William E. and Dai, Feng and Terrin, Norma and Magge, Subu N. and Coumans, Jean Valery C.E. and Harrington, J. Fred and Amin-hanjani, Sepideh and Schwartz, J. Sanford and Sonntag, Volker K.H. and Barker, Fred G. and Benzel, Edward C.},
doi = {10.1056/NEJMoa1508788},
file = {:Users/juandp77/Dropbox/references/New England Journal of Medicine/Laminectomy plus fusion versus laminectomy alone for lumbar spondylolisthesis - Ghogawala et al. - 2016(2).pdf:pdf},
issn = {15334406},
journal = {New England Journal of Medicine},
number = {15},
pages = {1424--1434},
title = {{Laminectomy plus fusion versus laminectomy alone for lumbar spondylolisthesis}},
volume = {374},
year = {2016}
}
@article{Benito2012,
abstract = {Objective: To assess the effect of high-frequency repetitive transcranial magnetic stimulation (rTMS) on lower extremities motor score (LEMS) and gait in patients with motor incomplete spinal cord injury (SCI). Method: The prospective longitudinal randomized, double-blind study assessed 17 SCI patients ASIA D. We assessed LEMS, modified Ashworth Scale (MAS), 10-m walking test (10MWT), Walking Index for SCI (WISCI II) scale, step length, cadence, and Timed Up and Go (TUG) test at baseline, after the last of 15 daily sessions of rTMS and 2 weeks later. Patients were randomized to active rTMS or sham stimulation. Three patients from the initial group of 10 randomized to sham stimulation entered the active rTMS group after a 3-week washout period. Therefore a total of 10 patients completed each study condition. Both groups were homogeneous for age, gender, time since injury, etiology, and ASIA scale. Active rTMS consisted of 15 days of daily sessions of 20 trains of 40 pulses at 20 Hz and an intensity of 90{\%} of resting motor threshold. rTMS was applied with a double cone coil to the leg motor area. Results: There was a significant improvement in LEMS in the active group (28.4 at baseline and 33.2 after stimulation; P = .004) but not in the sham group (29.6 at baseline, and 30.9 after stimulation; P = .6). The active group also showed significant improvements in the MAS, 10MWT, cadence, step length, and TUG, and these improvements were maintained 2 weeks later. Following sham stimulation, significant improvement was found only for step length and TUG. No significant changes were observed in the WISCI II scale in either group. Conclusion: High-frequency rTMS over the leg motor area can improve LEMS, spasticity, and gait in patients with motor incomplete SCI. {\textcopyright} 2012 Thomas Land Publishers, Inc.},
author = {Benito, J. and Kumru, H. and Murillo, N. and Costa, U. and Medina, J. and Tormos, J. and Pascual-Leone, Alvaro and Vidal, J.},
doi = {10.1310/sci1802-106},
file = {:Users/juandp77/Dropbox/references/Topics in Spinal Cord Injury Rehabilitation/Motor and Gait Improvement in Patients With Incomplete Spinal Cord Injury Induced by High-Frequency Repetitive Transcranial Magnetic Sti.pdf:pdf},
issn = {1082-0744},
journal = {Topics in Spinal Cord Injury Rehabilitation},
keywords = {gait,spasticity,spinal cord injury,transcranial magnetic stimulation},
month = {apr},
number = {2},
pages = {106--112},
title = {{Motor and Gait Improvement in Patients With Incomplete Spinal Cord Injury Induced by High-Frequency Repetitive Transcranial Magnetic Stimulation}},
url = {http://archive.scijournal.com/doi/abs/10.1310/sci1802-106},
volume = {18},
year = {2012}
}
@article{Muhammad2020,
author = {Muhammad, Sajjad and Petridis, Athanasios and Cornelius, Jan Frederick and H{\"{a}}nggi, Daniel},
doi = {10.1016/j.bbi.2020.05.015},
file = {:Users/juandp77/Dropbox/references/Brain, Behavior, and Immunity/Letter to editor Severe brain haemorrhage and concomitant COVID-19 Infection A neurovascular complication of COVID-19 - Muhammad et al..pdf:pdf},
issn = {08891591},
journal = {Brain, Behavior, and Immunity},
month = {jul},
pages = {150--151},
title = {{Letter to editor: Severe brain haemorrhage and concomitant COVID-19 Infection: A neurovascular complication of COVID-19}},
url = {https://linkinghub.elsevier.com/retrieve/pii/S0889159120308023},
volume = {87},
year = {2020}
}
@misc{Solero1989,
abstract = {The long-term results obtained in a series of 174 patients operated on for spinal meningiomas are critically analyzed. This series was similar to those of other authors with regard to age, sex, location of the tumors, and clinical presentation. Before surgery, about 70{\%} of the patients were included in Groups I and II (mild neurological impairment), and about 30{\%} of the patients were classified in Groups III and IV (significant to severe neurological impairment, up to paraplegia). Complete tumor removal was achieved in 96.5{\%} of the patients, and surgical mortality was about 1{\%}. Microsurgical technique, which was adopted in the last 29 cases, proved to be very effective in reducing undue damage to the spinal cord and in minimizing the postoperative neurological deficits. Of the 174 patients who underwent surgery, 156 underwent late follow-up study for an average of 15 years (2 patients died in the immediate postoperative period, and 16 patients were lost to follow-up). Twenty-nine patients died of causes unrelated to the spinal meningioma; of the remaining 126 patients, 92{\%} were categorized in Groups I and II, and only 8{\%} in Groups III and IV. The rate of recurrence was 6{\%} (9 patients) among the 150 patients who had complete tumor removal, and the rate of regrowth was 17{\%} (1 patient with anaplastic meningioma) among the 6 patients treated by subtotal removal. The early diagnosis of the disease and the use of microsurgical technique appeared as the most relevant factors for further improvement of the surgical results.},
author = {Solero, C. L. and Fornari, M. and Giombini, S. and Lasio, G. and Oliveri, G. and Cimino, C. and Pluchino, F. and Gelber, B. R.},
booktitle = {Neurosurgery},
doi = {10.1227/00006123-198908000-00001},
isbn = {0148-396X (Print)$\backslash$r0148-396X (Linking)},
issn = {0148396X},
number = {2},
pages = {153--160},
pmid = {2671779},
title = {{Spinal meningiomas: Review of 174 operated cases}},
volume = {25},
year = {1989}
}
@article{Ashley2006a,
abstract = {Background: An anterior sacral meningocele is a rare form of spinal dysraphism that is sometimes associated with syndromes such as Currarino and Marfan syndromes. These lesions rarely cause neurological complications, but meningitis, sepsis, obstetric problems, and bowel and bladder difficulties are common secondary conditions. The lesions can even be fatal. Because these lesions usually do not regress spontaneously, surgical treatment is the standard for symptomatic or growing masses. The dural defect can be repaired with a variety of anterior or posterior approaches. Case Description: We present a case of a 16-year-old female patient with a giant nonsyndromic anterior sacral meningocele that we successfully treated using an open anterior approach. We discuss the treatment options and present a brief review of the literature. Conclusions: Although the posterior approach remains the treatment of choice for most lesions, we believe that the anterior laparotomy provides excellent exposure and is a safe alternative approach for the treatment of selected lesions. Patients with these lesions should be cared for by a multidisciplinary team. ?? 2006 Elsevier Inc. All rights reserved.},
author = {Ashley, William W. and Wright, Neill M.},
doi = {10.1016/j.surneu.2005.10.020},
isbn = {0090-3019 (Print)},
issn = {00903019},
journal = {Surgical Neurology},
keywords = {Anterior sacral meningocele,Pelvic mass,Spinal dysraphism},
number = {1},
pages = {89--93},
pmid = {16793455},
title = {{Resection of a giant anterior sacral meningocele via an anterior approach: case report and review of literature}},
volume = {66},
year = {2006}
}
@article{Prasad2016,
abstract = {Objective The physiological mechanisms underlying the recovery of motor function after cervical spondylotic myelopathy (CSM) surgery are poorly understood. Neuronal plasticity allows neurons to compensate for injury and disease and to adjust their activities in response to new situations or changes in their environment. Cortical reorganization as well as improvement in corticospinal conduction happens during motor recovery after stroke and spinal cord injury. In this study the authors aimed to understand the cortical changes that occur due to CSM and following CSM surgery and to correlate these changes with functional recovery by using blood oxygen level-dependent (BOLD) functional MRI (fMRI). Methods Twenty-two patients having symptoms related to cervical cord compression due to spondylotic changes along with 12 age- and sex-matched healthy controls were included in this study. Patients underwent cervical spine MRI and BOLD fMRI at 1 month before surgery (baseline) and 6 months after surgery. Results Five patients were excluded from analysis because of technical problems; thus, 17 patients made up the study cohort. The mean overall modified Japanese Orthopaedic Association score improved in patients following surgery. Mean upper-extremity, lower-extremity, and sensory scores improved significantly. In the preoperative patient group the volume of activation (VOA) was significantly higher than that in controls. The VOA after surgery was reduced as compared with that before surgery, although it remained higher than that in the control group. In the preoperative patient group, activations were noted only in the left precentral gyrus (PrCG). In the postoperative group, activations were seen in the left postcentral gyrus (PoCG), as well as the PrCG and premotor and supplementary motor cortices. In postoperative group, the VOA was higher in both the PrCG and PoCG as compared with those in the control group. Conc lusions There is over-recruitment of sensorimotor cortices during nondexterous relative to dexterous movements before surgery. After surgery, there was recruitment of other cortical areas such as the PoCG and premotor and supplementary motor cortices, which correlated with improvement in dexterity, but activation in these areas was greater than that found in controls. The results show that improvement in dexterity and finer movements of the upper limbs is associated with recruitment areas other than the premotor cortex to compensate for the damage in the cervical spinal cord.},
author = {Bhagavatula, Indira Devi and Shukla, Dhaval and Sadashiva, Nishanth and Saligoudar, Praveen and Prasad, Chandrajit and Bhat, Dhananjaya I.},
doi = {10.3171/2016.3.FOCUS1635},
file = {:Users/juandp77/Dropbox/references/Neurosurgical Focus/Functional cortical reorganization in cases of cervical spondylotic myelopathy and changes associated with surgery - Bhagavatula et al..pdf:pdf},
issn = {10920684},
journal = {Neurosurgical Focus},
keywords = {Cervical spondylotic myelopathy,Cortical plasticity,Functional magnetic resonance imaging},
number = {6},
pages = {E2},
title = {{Functional cortical reorganization in cases of cervical spondylotic myelopathy and changes associated with surgery}},
url = {https://thejns.org/view/journals/neurosurg-focus/40/6/article-pE2.xml},
volume = {40},
year = {2016}
}
@article{Surgeons.2007,
abstract = {First lines: TRAUMATIC BRAIN INJURY (TBI) is a major cause of disability, death, and economic cost to our society. One of the central concepts that emerged from research is that all neurological damage from TBI does not occur at the moment of impact, but evolves over the ensuing hours and days. Furthermore, improved outcome results when these secondary, delayed insults, resulting in reduced cerebral perfusion to the injured brain, are prevented or respond to treatment. This is reflected in the progressive and significant reduction in severe TBI mortality from 50{\%} to 35{\%} to 25{\%} and lower over the last 30 years, even when adjusted for injury severity, age and other admission prognostic parameters.1 This trend in reduced mortality and improved outcomes from TBI has been subsequent to the use of evidence-based protocols that emphasize monitoring and maintaining adequate cerebral perfusion.2,3},
author = {Surgeons., Brain Trauma Foundation; American Association of Neurological Surgeons; Congress of Neurological},
doi = {10.1089/neu.2007.9990},
isbn = {087977151F},
issn = {08977151},
journal = {Journal of neurosurgery},
keywords = {Practice Guideline,Severe Traumatic Brain Injury,Traumatic Brain Injury,Traumatic Brain Injury: therapy},
number = {212},
pages = {S1--106},
pmid = {17511534},
title = {{Guidelines for the Management of Severe Traumatic Brain Injury 3rd Edition}},
url = {http://www.ncbi.nlm.nih.gov/pubmed/17511534},
volume = {24, Suppl },
year = {2007}
}
@article{Cossu2017,
abstract = {The rationale and the surgical technique of stereo-electroencephalography (SEEG)–guided radiofrequency thermocoagulation (RF-TC) in the epileptogenic zone (EZ) of patients with difficult-to-treat focal epilepsy are described in this article. The application of the technique in pediatric patients is also detailed. Stereotactic ablative procedures by RF-TC have been employed in the treatment of epilepsy since the middle of the last century. This treatment option has gained new popularity in recent decades, mainly because of the availability of modern imaging techniques, which allow accurate targeting of intracerebral epileptogenic structures. SEEG is a powerful tool for identifying theEZin the most challenging cases of focal epilepsy by recording electrical activity with tailored stereotactic implantation of multilead intracerebral electrodes. The same recording electrodes may be used to place thermocoagulative lesions in the EZ, following the indications provided by intracerebral monitoring. The technical details of SEEG implantation and of SEEG-guided RF-TC are described herein, with special attention to the employment of the procedure in pediatric cases. SEEG-guided RF-TC offers a potential therapeutic option based on robust electroclinical evidence with acceptable risks and costs. The procedure may be performed in patients who, according to SEEG recording, are not eligible for resective surgery, and it may be an alternative to resective surgery in a small subset of operable patients.},
author = {Cossu, Massimo and Cardinale, Francesco and Casaceli, Giuseppe and Castana, Laura and Consales, Alessandro and D'Orio, Piergiorgio and {Lo Russo}, Giorgio},
doi = {10.1111/epi.13687},
file = {:Users/juandp77/Dropbox/references/Epilepsia/Stereo-EEGguided radiofrequency thermocoagulations - Cossu et al. - 2017.pdf:pdf},
issn = {15281167},
journal = {Epilepsia},
keywords = {Drug-resistant epilepsy,Epileptogenic zone,Radiofrequency thermocoagulation,Seizure outcome,Stereo-electroencephalography,Stereotactic surgery},
pages = {66--72},
title = {{Stereo-EEG???guided radiofrequency thermocoagulations}},
volume = {58},
year = {2017}
}
@article{Tetreault2017,
abstract = {{\textcopyright} 2016 Springer-Verlag Berlin HeidelbergPurpose: We aimed to determine cut-offs between mild, moderate and severe myelopathy on the modified Japanese Orthopedic Association (mJOA) score. Methods: Between December 2005 and January 2011, 757 patients with clinically diagnosed DCM were enrolled in the prospective AOSpine North America (n = 278) or International (n = 479) study at 26 sites. Functional status and quality of life were evaluated at baseline using a variety of outcome measures. Using the Nurick score as an anchor, receiver operating curve (ROC) analysis was conducted to determine cut-offs between mild, moderate and severe disease. The validity of the identified cut-offs was evaluated by examining whether patients in different severity groups differed in terms of impairment, disability, quality of life and number of signs and symptoms. Results: A mJOA of 14 was determined to be the cut-off between mild and moderate myelopathy and a mJOA of 11 was the cut-off score between moderate and severe disease. Patients in the severe myelopathy group (n = 254) had significantly reduced quality of life and functional status and a greater number of signs and symptoms compared to patients classified as mild (n = 190) or moderate (n = 296). Conclusions: Mild myelopathy can be defined as mJOA from 15 to 17, moderate as mJOA from 12 to 14 and severe as mJOA from 0 to 11. These categories should be adopted worldwide to standardize clinical assessment of DCM.},
author = {Tetreault, Lindsay and Kopjar, Branko and Nouri, Aria and Arnold, Paul and Barbagallo, Giuseppe and Bartels, Ronald and Qiang, Zhou and Singh, Anoushka and Zileli, Mehmet and Vaccaro, Alexander and Fehlings, Michael G.},
doi = {10.1007/s00586-016-4660-8},
file = {:Users/juandp77/Dropbox/references/European Spine Journal/The modified Japanese Orthopaedic Association scale establishing criteria for mild, moderate and severe impairment in patients with d(3).pdf:pdf},
isbn = {0058601646608},
issn = {14320932},
journal = {European Spine Journal},
keywords = {Defining disease severity,Degenerative cervical myelopathy,Functional impairment,Measurement,Modified Japanese Orthopaedic Association scale},
number = {1},
pages = {78--84},
pmid = {27342612},
title = {{The modified Japanese Orthopaedic Association scale: establishing criteria for mild, moderate and severe impairment in patients with degenerative cervical myelopathy}},
volume = {26},
year = {2017}
}
@article{Aguilar2010,
abstract = {Spinal cord injury can produce extensive long-term reorganization of the cerebral cortex. Little is known, however, about the sequence of cortical events starting immediately after the lesion. Here we show that a complete thoracic transection of the spinal cord produces immediate functional reorganization in the primary somatosensory cortex of anesthetized rats. Besides the obvious loss of cortical responses to hindpaw stimuli (below the level of the lesion), cortical responses evoked by forepaw stimuli (above the level of the lesion) markedly increase. Importantly, these increased responses correlate with a slower and overall more silent cortical spontaneous activity, representing a switch to a network state of slow-wave activity similar to that observed during slow-wave sleep. The same immediate cortical changes are observed after reversible pharmacological block of spinal cord conduction, but not after sham. We conclude that the deafferentation due to spinal cord injury can immediately (within minutes) change the state of large cortical networks, and that this state change plays a critical role in the early cortical reorganization after spinal cord injury.},
author = {Aguilar, J. and Humanes-Valera, D. and Alonso-Calvino, E. and Yague, J. G. and Moxon, K. A. and Oliviero, A. and Foffani, G.},
doi = {10.1523/JNEUROSCI.0379-10.2010},
file = {:Users/juandp77/Dropbox/references/Journal of Neuroscience/Spinal Cord Injury Immediately Changes the State of the Brain - Aguilar et al. - 2010.pdf:pdf},
issn = {0270-6474},
journal = {Journal of Neuroscience},
number = {22},
pages = {7528--7537},
title = {{Spinal Cord Injury Immediately Changes the State of the Brain}},
url = {http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.0379-10.2010},
volume = {30},
year = {2010}
}
@article{Galzio2010,
author = {Galzio, Renato J. and Tschabitscher, Manfred and Ricci, Alessandro},
doi = {10.1007/978-88-470-1167-0_6},
file = {:Users/juandp77/Dropbox/references/Unknown/Orbitozygomatic Approach - Galzio, Tschabitscher, Ricci - 2010.pdf:pdf},
pages = {61--86},
title = {{Orbitozygomatic Approach}},
year = {2010}
}
@article{Sandalcioglu2008,
abstract = {This study was undertaken to analyze the functional outcome of surgically treated spinal meningiomas and to determine factors for surgical morbidity. Between January 1990 and December 2006 a total of 131 patients underwent surgical resection of a spinal menigioma. There were 114 (87{\%}) female and 17 (13{\%}) male patients. Age ranged from 17 to 88 years (mean 69 years). The mean follow-up period was 61 months (range 1-116 months) including a complete neurological examination and postoperative MRI studies. The pre- and postoperative neurological state was graded according to the Frankel Scale. Surgery was performed under standard microsurgical conditions with neurophysiological monitoring. In 73{\%} the lesion was located in the thoracic region, in 16{\%} in the cervical region, in 5{\%} at the cervico-thoracic junction, in 4.5{\%} at the thoraco-lumbar junction and in 1.5{\%} in the lumbar region. Surgical resection was complete in 127 patients (97{\%}) and incomplete in 4 patients (3{\%}). At the last follow-up the neurological state was improved or unchanged in 126 patients (96.2{\%}) and worse in 4 patients (3{\%}). Permanent operative morbidity and mortality rates were 3 and 0.8{\%}, respectively. Extensive tumour calcification proved to be a significant factor for surgical morbidity (P {\textless} 0.0001). Radical resection of spinal meningiomas can be performed with good functional results. Extensive tumor calcification, especially in elderly patients proved to harbor an increased risk for surgical morbidity.},
author = {Sandalcioglu, I. Erol and Hunold, Anja and M{\"{u}}ller, Oliver and Bassiouni, Hischam and Stolke, Dietmar and Asgari, Siamak},
doi = {10.1007/s00586-008-0685-y},
file = {:Users/juandp77/Dropbox/references/European Spine Journal/Spinal meningiomas Critical review of 131 surgically treated patients - Sandalcioglu et al. - 2008.pdf:pdf},
isbn = {1432-0932 (Electronic)$\backslash$r0940-6719 (Linking)},
issn = {09406719},
journal = {European Spine Journal},
keywords = {Meningioma,Outcome,Spinal meningioma,Spinal tumours,Surgery},
number = {8},
pages = {1035--1041},
pmid = {18481118},
title = {{Spinal meningiomas: Critical review of 131 surgically treated patients}},
volume = {17},
year = {2008}
}
@article{Li2013,
abstract = {BACKGROUND AND PURPOSE: Endovascular treatment has increasingly been used for aneurismal subarachnoid aneurismal hemorrhage. The aim of this analysis is to assess the current evidence regarding safety and efficiency of clipping compared with coiling.$\backslash$n$\backslash$nMETHODS: We conducted a meta-analysis of studies that compared clipping with coiling between January 1999 and July 2012. Comparison of binary outcomes between treatment groups was described using odds ratios (OR; clip versus coil).$\backslash$n$\backslash$nRESULTS: Four randomized controlled trials and 23 observational studies were included. Randomized controlled trials showed that coiling reduced the 1-year unfavorable outcome rate (OR, 1.48; 95{\%} confidence interval [CI], 1.24-1.76). However, there was no statistical deference in nonrandomized controlled trials (OR, 1.11; 95{\%} CI, 0.96-1.28). Subgroup analysis revealed coiling yielded better outcomes for patients with good preoperative grade (OR, 1.51; 95{\%} CI, 1.24-1.84) than for poor preoperative patients (OR, 0.88; 95{\%} CI 0.56-1.38). Additionally, the incidence of rebleeding is higher after coiling (OR, 0.43; 95{\%} CI, 0.28-0.66), corresponding to a better complete occlusion rate of clipping (OR, 2.43; 95{\%} CI, 1.88-3.13). The 1-year mortality showed no significant difference (OR, 1.07; 95{\%} CI, 0.88-1.30). Vasospasm was more common after clipping (OR, 1.43; 95{\%} CI, 1.07-1.91), whereas the ischemic infarct (OR, 0.74; 95{\%} CI, 0.52-1.06), shunt-dependent hydrocephalus (OR, 0.84; 95{\%} CI, 0.66-1.07), and procedural complication rates (OR, 1.19; 95{\%} CI, 0.67-2.11) did not differ significantly between techniques.$\backslash$n$\backslash$nCONCLUSIONS: Coiling yields a better clinical outcome, the benefit being greater in those with a good preoperative grade than those with a poor preoperative grade. However, coiling leads to a greater risk of rebleeding. Well-designed randomized trials with special considerations to the aspect are needed.},
author = {Li, Hui and Pan, Rui and Wang, Hongxuan and Rong, Xiaoming and Yin, Zi and Milgrom, Daniel P. and Shi, Xiaolei and Tang, Yamei and Peng, Ying},
doi = {10.1161/STROKEAHA.112.663559},
isbn = {1524-4628 (Electronic)$\backslash$r0039-2499 (Linking)},
issn = {00392499},
journal = {Stroke},
keywords = {cerebral aneurysm,clip,coil,meta-analysis,subarachnoid hemorrhage},
number = {1},
pages = {29--37},
pmid = {23238862},
title = {{Clipping versus coiling for ruptured intracranial aneurysms: A systematic review and meta-analysis}},
volume = {44},
year = {2013}
}
@incollection{Fernandes2014,
abstract = {OBJECT: The authors provide a detailed review of the surgical management of trigeminal schwannomas (TSs) and also discuss the best surgical approach based on the surgical anatomy and tumor extension. METHODS: A series of 17 patients with TSs who were surgically treated between 1987 and 2008 at the authors' institution is reported. The lesions were small ({\textless} 3 cm) in 2, medium (between 3 and 4 cm) in 5, large ({\textgreater} 4 cm) in 6, and giant ({\textgreater} 5 cm) in 4 cases. Preoperative symptoms included trigeminal hypesthesia (53{\%}), facial pain (53{\%}), headaches (35.3{\%}), hearing impairment (17.6{\%}), seizures (17.6{\%}), diplopia (11.8{\%}), ataxia (11.8{\%}), and hemiparesis and increased intracranial pressure with papilledema (5.9{\%}). The mean follow-up duration was 10.5 years (121.6 months), with an average of 0.8 patients per year. RESULTS: Total tumor excision was possible in 16 patients, with no surgery-related deaths. Postoperative trigeminal anesthesia was observed in 7; trigeminal motor function was preserved in 7. Two developed cerebrospinal fluid leakage, 2 presented with mild facial palsy, and 1 patient with neurofibromatosis Type 2 had recurrence of the tumor, which was uneventfully removed. Of the 9 who reported facial pain, only 1 remained symptomatic postoperatively. CONCLUSIONS: The best treatment for TSs is complete microsurgical removal. Postoperative preservation of trigeminal nerve function is possible when resection of the lesion is performed at well-established skull base neurosurgical centers. Although good results have been reported with radiosurgery, no cure can be obtained with this therapeutic modality. Instead, this treatment should be reserved only for nonresectable and residual tumors within the cavernous sinus.},
author = {Fernandes, Yvens Barbosa and Neto, Mauricio Coelho and Leal, Andr{\'{e}} Giacomelli and {Da Silva}, Erasmo Barros and Aurich, Lucas Alves},
booktitle = {Samii's Essentials in Neurosurgery},
doi = {10.1007/978-3-642-54115-5_21},
isbn = {9783642541155},
issn = {1092-0684},
pages = {237--250},
pmid = {19035703},
title = {{The surgical management of trigeminal schwannomas}},
year = {2014}
}
@article{Sala2003,
abstract = {AIM: Surgery for tumors in the central and precentral region, as much as for insular tumors, places at risk the functional integrity of the motor cortex and the subcortical motor pathways. These procedures may therefore benefit from the assistance of intraoperative neurophysiological monitoring (INM). INM consists of "mapping" and true "monitoring" (the continuous "on-line" assessment of the functional integrity of neural pathways) techniques. In spite of the large interest in mapping techniques, monitoring techniques have received less attention. We describe our experience with intraoperative neurophysiological mapping and monitoring of motor tracts during surgery for brain gliomas in or near motor areas, in order to support the feasibility and reliability of monitoring as an essential adjunct to mapping during surgery in these areas. METHODS: Between September 2000 and January 2002, 51 patients were surgically treated for brain gliomas located in the precentral gyrus (45.1{\%}), the postcentral gyrus (23.5{\%}), anterior to the precentral gyrus (15.6{\%}), or in the insula (15.6{\%}). INM of the motor system consisted of monitoring muscle motor evoked potentials (mMEPs) recorded via needle electrodes inserted into the controlateral upper and lower extremity muscles and elicited by transcranial multipulse electrical stimulation (TES). Once the dura was open and the central sulcus was identified using the phase reversal technique, mMEPs were elicited by direct stimulation of the motor cortex (DCS). Motor mapping was performed with a monopolar electrode using the same stimulation parameters as used for monitoring except for much lower intensity (up to 20 mA). RESULTS: Ninety-eight percent of the patients exhibited recordable baseline mMEPs. The success rate of the phase reversal technique was 95.8{\%}. Eight patients presented disappearance of mMEPs during tumor removal. Using corrective measures, all intraoperative changes in mMEPs were reversed in time to prevent an irreversible complete injury to the motor system and no patient lost mMEPs at the end of the operation. At discharge, 66{\%} of the patients remained at their preoperative status, 4{\%} improved, and 24{\%} had a mild worsening as compared to the preoperative status assessed using the Medical Research Council scale; 6{\%} of the patients presented a moderate to severe supplementary motor area syndrome. CONCLUSION: Monitoring techniques significantly implement the reliability and effectiveness of INM since these provide: 1) continuous "on-line" assessment of the functional integrity of motor pathways with higher chance to early detect a progressive mechanical or vascular injury to the neural tissue, as compared to mapping techniques; 2) lower risk to induce intraoperative seizures and strong muscular twitches as compared to the single pulse mapping technique; 3) possibility to monitor motor pathways using TES also when there is no direct access to the motor cortex.},
author = {Sala, F and Lanteri, P},
issn = {0390-5616},
journal = {Journal of neurosurgical sciences},
number = {2},
pages = {79--88},
pmid = {14618135},
title = {{Brain surgery in motor areas: the invaluable assistance of intraoperative neurophysiological monitoring.}},
volume = {47},
year = {2003}
}
@article{Hutchinson2016,
abstract = {BackgroundThe effect of decompressive craniectomy on clinical outcomes in patients with refractory traumatic intracranial hypertension remains unclear. MethodsFrom 2004 through 2014, we randomly assigned 408 patients, 10 to 65 years of age, with traumatic brain injury and refractory elevated intracranial pressure ({\textgreater}25 mm Hg) to undergo decompressive craniectomy or receive ongoing medical care. The primary outcome was the rating on the Extended Glasgow Outcome Scale (GOS-E) (an 8-point scale, ranging from death to “upper good recovery” [no injury-related problems]) at 6 months. The primary-outcome measure was analyzed with an ordinal method based on the proportional-odds model. If the model was rejected, that would indicate a significant difference in the GOS-E distribution, and results would be reported descriptively. ResultsThe GOS-E distribution differed between the two groups (P{\textless}0.001). The proportional-odds assumption was rejected, and therefore results are reported descriptively. At 6 months, the GOS...},
author = {Hutchinson, Peter J. and Kolias, Angelos G. and Timofeev, Ivan S. and Corteen, Elizabeth A. and Czosnyka, Marek and Timothy, Jake and Anderson, Ian and Bulters, Diederik O. and Belli, Antonio and Eynon, C. Andrew and Wadley, John and Mendelow, A. David and Mitchell, Patrick M. and Wilson, Mark H. and Critchley, Giles and Sahuquillo, Juan and Unterberg, Andreas and Servadei, Franco and Teasdale, Graham M. and Pickard, John D. and Menon, David K. and Murray, Gordon D. and Kirkpatrick, Peter J.},
doi = {10.1056/NEJMoa1605215},
file = {:Users/juandp77/Dropbox/references/New England Journal of Medicine/Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension - Hutchinson et al. - 2016.pdf:pdf},
issn = {0028-4793},
journal = {New England Journal of Medicine},
pages = {NEJMoa1605215},
pmid = {27602507},
title = {{Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension}},
year = {2016}
}
@book{Klekamp2007,
author = {Klekamp, J{\"{o}}rg and Samii, Madjid},
booktitle = {Surgery of Spinal Tumors},
doi = {10.1007/978-3-540-44715-3},
isbn = {9783540447146},
pages = {1--526},
title = {{Surgery of spinal tumors}},
year = {2007}
}
@article{Massimi2003,
abstract = {OBJECT: Anterior sacral meningocele (ASM) is a rare congenital malformation. Often while still asymptomatic, ASM may achieve a considerably size, to the extent of exerting a mass effect on the pelvic structures. Spontaneous rupture with subsequent septic meningitis is the most frequent and dangerous complication. The meningocelic sac is usually isolated by a surgical procedure that requires a sacral laminectomy or a transabdominal approach. Recently an alternative surgical technique, the posterior sagittal approach, has been proposed. METHODS: We report on a 15-year-old girl with a long clinical history of constipation and sporadic cystitis. Radiological examinations showed progressive enlargement of a presacral lipomeningocele, which grew to 12x14 cm. A posterior sagittal approach was performed; the stalk was ligated, the sac totally excised and a small associated tumour removed. No intra-/post-operative complications were observed. CONCLUSION: The posterior sagittal approach is an easy and safe surgical technique for the treatment of ASM, as it allows a complete isolation of the lesion and the removal of associated tumors without significant morbidity.},
author = {Massimi, Luca and Calisti, Alessandro and Koutzoglou, Michalis and {Di Rocco}, Concezio},
doi = {10.1007/s00381-003-0814-1},
file = {:Users/juandp77/Dropbox/references/Child's Nervous System/Giant anterior sacral meningocele and posterior sagittal approach - Massimi et al. - 2003.pdf:pdf},
issn = {02567040},
journal = {Child's Nervous System},
keywords = {Anterior sacral meningocele,Posterior sagittal approach},
pmid = {14576957},
title = {{Giant anterior sacral meningocele and posterior sagittal approach}},
year = {2003}
}
@article{Dorfer2013,
abstract = {Neurosurg Focus 34 (6):E10, 2013 1 {\textcopyright}AANS, 2013 M ultilobar pathologies—making up 12{\%}–22{\%} of large epilepsy surgery series in children and 3{\%}–9{\%} of mixed pediatric/adult series—are not uncommon etiologies in early-onset drug-resistant epileptic encephalopathies. 17 Children with intractable epilepsy due to extensive lesions involving the posterior quadrant (temporal, parietal, and occipital lobes) form a significant subset of this population. Early epilepsy sur-gery is the treatment of choice in most of these patients, but conventional resective surgery carries substantial op-erative risks. Similar to the continuous evolution of disconnective techniques in functional hemispherectomy, the surgical approach for TPO epilepsies has evolved progressively toward more disconnection and less resection. 5,6,18,20,21 Disconnective procedures are based on the concept that interrupting the epileptic discharge–spreading path-way and isolating the primary epileptogenic zone would have the same effect as removing the epileptic focus. The potential benefits of this approach include smaller crani-otomies, reduced blood loss, and fewer long-term compli- Object. Outcomes following functional hemispherotomy in patients with drug-resistant epilepsy have been well described. However, studies reporting long-term longitudinal outcomes after subhemispheric disconnective epilepsy surgery are still limited. Methods. The authors conducted a retrospective review of prospectively collected data of 10 children who un-derwent temporoparietooccipital (TPO) disconnective surgery at the Vienna Pediatric Epilepsy Center. Results. There were 3 males and 7 females (median age 8.7 years; range 4.2–22.1 years). The affected hemi-sphere was the left in 3 patients and the right in 7. The patients' median age at seizure onset was 3.0 years (range 0.2–8.3 years). The median duration of epilepsy before surgery was 5.2 years (range 1.3–17.2 years). The underlying pathology was TPO malformation of cortical development in 5 patients, and venous infarction, posterior hemispheric quadrant atrophy, Sturge-Weber syndrome, cortical involvement of a systemic lupus erythematosus, and gliosis after cerebral tumor treatment in 1 each. In 6 children, a pure TPO disconnection was performed; in 2 patients, the tempo-ral lobe was resected and parietooccipital disconnection was performed. The 2 remaining patients had had previous epilepsy surgery that was extended to a TPO disconnection: disconnection of the occipital lobe (n = 1) and resection of the temporal lobe (n = 1). The authors encountered no complications while performing surgery. No patient needed blood replacement therapy. No patient developed CSF disturbances that warranted treatment. Nine of 10 patients are currently seizure free since surgery (Wieser Class 1a) at a median follow-up time of 2.1 years (range 4 months to 8.1 years). Conclusions. Temporoparietooccipital disconnection is a safe and effective motor-sparing epilepsy surgery in selected cases. Technical adjuncts facilitate a better intraoperative visualization and orientation, thereby enabling a less invasive approach than previously suggested. (http://thejns.org/doi/abs/10.3171/2013.3.FOCUS1362) key WorDs • posterior quadrantic epilepsy • temporoparietooccipital surgery • 3D surface navigation • intraoperative monitoring • pediatric epilepsy surgery 1 Abbreviations used in this paper: AED = antiepileptic drug; EEG = electroencephalography; FDG = fluorine-18–labeled fluorodeoxy-glucose; MEP = motor evoked potential; PO = parietoocipital; SEP = somatosensory evoked potential; TPO = temporoparietooccipital. C. Dorfer et al. 2 Neurosurg Focus / Volume 34 / June 2013 cations, such as hemosiderosis and disturbances of CSF circulation, without minimizing the effect on postopera-tive seizure outcome. On the other hand, disconnective surgery can theoretically run the risk of leaving the epi-leptogenic cortex connected to the rest of the brain due to complicated intraoperative orientation. New techniques, including 3D surface navigation and intraoperative monitoring, further minimize brain ex po-sure and facilitate a safe and complete disconnection based on a precise understanding of the relevant anatomy. We present our experience using these techniques in our series of TPO disconnections.},
author = {Dorfer, Christian and Czech, Thomas and M{\"{u}}hlebner-Fahrngruber, Angelika and Mert, Ayg{\"{u}}l and Gr{\"{o}}ppel, Gudrun and Novak, Klaus and Dressler, Anastasia and Reiter-Fink, Edith and Traub-Weidinger, Tatjana and Feucht, Martha},
doi = {10.3171/2013.3.FOCUS1362},
file = {:Users/juandp77/Dropbox/references/Neurosurg Focus/Disconnective surgery in posterior quadrantic epilepsy experience in a consecutive series of 10 patients - Dorfer et al. - 2013.pdf:pdf},
journal = {Neurosurg Focus},
title = {{Disconnective surgery in posterior quadrantic epilepsy: experience in a consecutive series of 10 patients}},
volume = {34},
year = {2013}
}
@article{Forsth2016a,
abstract = {{\textcopyright} 2016 Massachusetts Medical Society. BACKGROUND The efficacy of fusion surgery in addition to decompression surgery in patients who have lumbar spinal stenosis, with or without degenerative spondylolisthesis, has not been substantiated in controlled trials. METHODS We randomly assigned 247 patients between 50 and 80 years of age who had lumbar spinal stenosis at one or two adjacent vertebral levels to undergo either decompression surgery plus fusion surgery (fusion group) or decompression surgery alone (decompression-alone group). Randomization was stratified according to the presence of preoperative degenerative spondylolisthesis (in 135 patients) or its absence. Outcomes were assessed with the use of patient- reported outcome measures, a 6-minute walk test, and a health economic evaluation. The primary outcome was the score on the Oswestry Disability Index (ODI; which ranges from 0 to 100, with higher scores indicating more severe disability) 2 years after surgery. The primary analysis, which was a per-protocol analysis, did not include the 14 patients who did not receive the assigned treatment and the 5 who were lost to follow-up. RESULTS There was no significant difference between the groups in the mean score on the ODI at 2 years (27 in the fusion group and 24 in the decompression-alone group, P = 0.24) or in the results of the 6-minute walk test (397 m in the fusion group and 405 m in the decompression- Alone group, P = 0.72). Results were similar between patients with and those without spondylolisthesis. Among the patients who had 5 years of follow-up and were eligible for inclusion in the 5-year analysis, there were no significant differences between the groups in clinical outcomes at 5 years. The mean length of hospitalization was 7.4 days in the fusion group and 4.1 days in the decompression-alone group (P{\textless}0.001). Operating time was longer, the amount of bleeding was greater, and surgical costs were higher in the fusion group than in the decompression-alone group. During a mean follow-up of 6.5 years, additional lumbar spine surgery was performed in 22{\%} of the patients in the fusion group and in 21{\%} of those in the decompression-alone group. CONCLUSIONS Among patients with lumbar spinal stenosis, with or without degenerative spondylolisthesis, decompression surgery plus fusion surgery did not result in better clinical outcomes at 2 years and 5 years than did decompression surgery alone. (Funded by an Uppsala institutional Avtal om L{\"{a}}karutbildning och Forskning [Agreement concerning Cooperation on Medical Education and Research] and others; Swedish Spinal Stenosis Study ClinicalTrials.gov number, NCT01994512.).},
author = {Forsth, Peter and {\'{O}}lafsson, Gylfi and Carlsson, Thomas and Frost, Anders and Borgstrm, Fredrik and Fritzell, Peter and Ohagen, Patrik and Michalsson, Karl and Sand{\'{e}}n, Bengt},
doi = {10.1056/NEJMoa1513721},
file = {:Users/juandp77/Dropbox/references/New England Journal of Medicine/A Randomized, Controlled trial of fusion surgery for lumbar spinal stenosis - Forsth et al. - 2016.pdf:pdf},
issn = {15334406},
journal = {New England Journal of Medicine},
number = {15},
pages = {1413--1423},
title = {{A Randomized, Controlled trial of fusion surgery for lumbar spinal stenosis}},
volume = {374},
year = {2016}
}
@article{Schick2001,
abstract = {The outcome of surgical treatment of benign spinal neoplasms is considered to be excellent, with good improvement of neurological function. The risk of recurrence is estimated to be very low, except with subtotal resections. This retrospective study was designed to establish the course of illness, clinical outcome, and recurrence rate of benign spinal tumours. We present an overview of the clinical outcome and surgical treatment of 197 benign spinal tumours carried out in our centre from 1980 to 1999. Clinical history, signs, surgical approach, outcome, and radiological reports were obtained by reviewing patient charts. The most frequent benign tumour was meningeoma (41{\%}), closely followed by neurinoma (33{\%}) and neurofibroma (6.1{\%}). Of all tumours, 79.7{\%} were completely resected. Recurrence happened in 10.2{\%} on an average of 4.3 years postoperatively. Only 2 patients suffered from neurofibromatosis. All neurinomas were completely resected at first operation, whereas three out of seven recurrent meningeomas and all ependymomas were classified as subtotally resected. Seventy per cent were treated by repeated surgical intervention. Benign tumours usually can be completely removed without adding to patients' neurological deficits. Benign tumours recur in 10.2{\%} of cases, thus requiring long-term follow-up. Magnetic resonance imaging (MRI) studies are recommended up to 5 years postoperatively as a routine procedure.},
author = {Schick, U and Marquardt, G and Lorenz, R},
doi = {10.1007/PL00011961},
file = {:Users/juandp77/Dropbox/references/Neurosurg Rev/Recurrence of benign spinal neoplasms - Schick, Marquardt, Lorenz - 2001.pdf:pdf},
isbn = {0344-5607},
issn = {0344-5607 (Print)},
journal = {Neurosurg Rev},
keywords = {Adult,Aged,Diagnosis, Differential,Epidural Neoplasms/diagnosis/pathology/*surgery,Female,Humans,Male,Meningeal Neoplasms/diagnosis/pathology/surgery,Meningioma/diagnosis/pathology/surgery,Middle Aged,Neoplasm Recurrence, Local/diagnosis/pathology/*su,Neurilemmoma/diagnosis/pathology/surgery,Neurofibroma/diagnosis/pathology/surgery,Neurologic Examination,Retrospective Studies,Spinal Cord Neoplasms/diagnosis/pathology/*surgery,Spinal Cord/pathology,Spinal Neoplasms/diagnosis/pathology/*surgery,Spine/pathology,Treatment Outcome},
number = {1},
pages = {20--25},
pmid = {11339463},
title = {{Recurrence of benign spinal neoplasms}},
url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve{\&}db=PubMed{\&}dopt=Citation{\&}list{\_}uids=11339463},
volume = {24},
year = {2001}
}
@article{Ade2013,
abstract = {Background . Undiagnosed intracranial hypotension can result in several complications including subdural hematoma (SDH), subarachnoid hemorrhage (SAH), dural venous sinuses thrombosis (CVT), cranial nerve palsies, and stupor resulting from sagging of the brain. It is rare to see all the complications in one patient. Furthermore, imaging of the brain vasculature may reveal incidental asymptomatic small aneurysms. Given the combination of these imaging findings and a severe headache, the patients are often confused to have a primary subarachnoid hemorrhage. Case Report . We present a patient with spontaneous intracranial hypotension (SIH) who had an incidental ophthalmic artery aneurysm on MR imaging, and this presentation led to coiling of the aneurysm. The key aspect in the history “postural headaches” was missed, and this led to life threatening complications and unnecessary interventions. Revisiting the history and significant improvement in symptoms following an epidural blood patch resulted in the diagnosis of SIH. Conclusion . We strongly emphasize that appropriate history taking is the key in the diagnosis of SIH and providing timely treatment with an epidural blood patch could prevent potentially life threatening complications.},
author = {Ade, Swetha and Moonis, Majaz},
doi = {10.1155/2013/913465},
file = {:Users/juandp77/Dropbox/references/Case Reports in Neurological Medicine/Intracranial Hypotension with Multiple Complications An Unusual Case Report - Ade, Moonis - 2013.pdf:pdf},
issn = {2090-6668},
journal = {Case Reports in Neurological Medicine},
pages = {1--3},
publisher = {Hindawi Publishing Corporation},
title = {{Intracranial Hypotension with Multiple Complications: An Unusual Case Report}},
url = {http://dx.doi.org/10.1155/2013/913465 http://www.hindawi.com/journals/crinm/2013/913465/},
volume = {2013},
year = {2013}
}
@article{Cenic2005,
author = {Cenic, Aleksa and Bhandari, Mohit and Reddy, Kesava},
file = {:Users/juandp77/Dropbox/references/Can. J. Neurol. Sci/Management of Chronic Subdural Hematoma A National Survey and - Cenic, Bhandari, Reddy - 2005.pdf:pdf},
journal = {Can. J. Neurol. Sci.},
pages = {501--506},
title = {{Management of Chronic Subdural Hematoma : A National Survey and}},
year = {2005}
}
@article{Barzilai2018,
abstract = {Treatment paradigms for patients with spine metastases have evolved significantly over the past decade. Incorporating stereotactic radiosurgery into these paradigms has been particularly transformative, offering precise delivery of tumoricidal radiation doses with sparing of adjacent tissues. Evidence supports the safety and efficacy of radiosurgery as it currently offers durable local tumor control with low complication rates even for tumors previously considered radioresistant to conventional radiation. The role for surgical intervention remains consistent, but a trend has been observed toward less aggressive, often minimally invasive, techniques. Using modern technologies and improved instrumentation, surgical outcomes continue to improve with reduced morbidity. Additionally, targeted agents such as biologics and checkpoint inhibitors have revolutionized cancer care, improving both local control and patient survivals. These advances have brought forth a need for new prognostication tools and a more critical review of long-term outcomes. The complex nature of current treatment schemes necessitates a multidisciplinary approach including surgeons, medical oncologists, radiation oncologists, interventionalists, and pain specialists. This review recapitulates the current state-of-the-art, evidence-based data on the treatment of spinal metastases, integrating these data into a decision framework, NOMS, which integrates the 4 sentinel decision points in metastatic spine tumors: Neurologic, Oncologic, Mechanical stability, and Systemic disease and medical co-morbidities.},
author = {Barzilai, Ori and Fisher, Charles G and Bilsky, Mark H},
doi = {10.1093/neuros/nyx567},
file = {:Users/juandp77/Dropbox/references/Neurosurgery/State of the Art Treatment of Spinal Metastatic Disease - Barzilai, Fisher, Bilsky - 2018.pdf:pdf},
issn = {0148-396X},
journal = {Neurosurgery},
keywords = {1,10,1093,13,2017,com,doi,escc,neuros,neurosurgery 0,neurosurgery-online,noms,nyx567,radiosurgery,spine,srs,surgery,tumor,www},
number = {0},
pages = {1--13},
title = {{State of the Art Treatment of Spinal Metastatic Disease}},
volume = {0},
year = {2018}
}
@article{Catani2008,
abstract = {Diffusion tensor imaging (DTI) tractography allows perform virtual dissections of white matter pathways in the living human brain. In 2002, Catani et al. published a method to reconstruct white matter pathways using a region of interest (ROI) approach. The method produced virtual representations of white matter tracts faithful to classical post-mortem descriptions but it required detailed a priori anatomical knowledge. Here, using the same approach, we provide a template to guide the delineation of ROIs for the reconstruction of the association, projection and commissural pathways of the living human brain. The template can be used for single case studies and case-control comparisons. An atlas of the 3D reconstructions of the single tracts is also provided as anatomical reference in the Montreal Neurological Institute (MNI) space. {\textcopyright} 2008 Elsevier Masson Srl. All rights reserved.},
author = {Catani, Marco and {Thiebaut de Schotten}, Michel},
doi = {10.1016/j.cortex.2008.05.004},
file = {:Users/juandp77/Dropbox/references/Cortex/A diffusion tensor imaging tractography atlas for virtual in vivo dissections - Catani, Thiebaut de Schotten - 2008.pdf:pdf},
issn = {00109452},
journal = {Cortex},
keywords = {Connections,Diffusion Tensor Imaging (DTI),Tractography,White matter atlas},
number = {8},
pages = {1105--1132},
title = {{A diffusion tensor imaging tractography atlas for virtual in vivo dissections}},
volume = {44},
year = {2008}
}
@article{Schievink2005a,
abstract = {OBJECT: Spontaneous intracranial hypotension is a noteworthy but commonly misdiagnosed cause of new daily persistent headaches. Subdural fluid collections are frequent radiographic findings, but they can be interpreted as primary rather than secondary pathological entities, and uncertainties exist regarding their optimal management. The authors therefore reviewed their experience with subdural fluid collections in 40 consecutive patients with spontaneous spinal cerebrospinal fluid (CSF) leaks and intracranial hypotension. METHODS: The mean age of the 26 female and 14 male patients was 43 years (range 13-72 years). Subdural fluid collections were present in 20 patients (50{\%}); 12 of these patients (60{\%}) had subdural hygromas alone, and eight (40{\%}) had subacute to chronic subdural hematomas (SDHs) associated with significant mass effect. The subdural hygromas resolved within several days to weeks following treatment of the underlying CSF leak. Three patients with SDHs underwent evacuation of the hematoma prior to the establishment of the diagnosis of spontaneous intracranial hypotension, but the SDHs did not resolve until the underlying spinal CSF leak was treated. In the remaining five patients, the CSF leak was treated primarily and the SDHs resolved over a 1- to 3-month period without the need for evacuation. CONCLUSIONS: Subdural fluid collections are common in spontaneous intracranial hypotension, varying in appearance from thin subdural hygromas to large SDHs associated with significant mass effect. These collections can be safely managed by directing treatment at the underlying CSF leak without the need for hematoma evacuation.},
author = {Schievink, Wouter I and Maya, M Marcel and Moser, Franklin G and Tourje, James},
doi = {10.3171/jns.2005.103.4.0608},
isbn = {0022-3085 (Print)$\backslash$r0022-3085 (Linking)},
issn = {0022-3085},
journal = {Journal of neurosurgery},
number = {4},
pages = {608--613},
pmid = {16266041},
title = {{Spectrum of subdural fluid collections in spontaneous intracranial hypotension.}},
volume = {103},
year = {2005}
}
@article{Poeppel2012,
abstract = {Theoretical advances in language research and the availability of increasingly high-resolution experimental techniques in the cognitive neurosciences are profoundly changing how we investigate and conceive of the neural basis of speech and language processing. Recent work closely aligns language research with issues at the core of systems neuroscience, ranging from neurophysiological and neuroanatomic characterizations to questions about neural coding. Here we highlight, across different aspects of language processing (perception, production, sign language, meaning construction), new insights and approaches to the neurobiology of language, aiming to describe promising new areas of investigation in which the neurosciences intersect with linguistic research more closely than before. This paper summarizes in brief some of the issues that constitute the background for talks presented in a symposium at the Annual Meeting of the Society for Neuroscience. It is not a comprehensive review of any of the issues that are discussed in the symposium.},
author = {Poeppel, D. and Emmorey, K. and Hickok, G. and Pylkkanen, L.},
doi = {10.1523/JNEUROSCI.3244-12.2012},
file = {:Users/juandp77/Dropbox/references/Journal of Neuroscience/Towards a New Neurobiology of Language - Poeppel et al. - 2012.pdf:pdf},
isbn = {0270-6474},
issn = {0270-6474},
journal = {Journal of Neuroscience},
number = {41},
pages = {14125--14131},
pmid = {23055482},
title = {{Towards a New Neurobiology of Language}},
volume = {32},
year = {2012}
}
@article{NHSEngland2020,
abstract = {To be read in conjunction with the letter to midwives (titled: Safeguarding infants during the coronavirus pandemic: the ICON programme) and the ICON leaflet. The coronavirus pandemic and the associated social isolation will put huge pressures on families who will remain in a confined space. This will be a very stressful time for the parents of new babies. Abusive injury of babies is most common in the 6 to 12 th weeks of life when it is normal for babies to cry a lot. The injury is caused by a parent, most often the male partner/carer. Simple, clear advice from midwives, health visitors and other health care professionals in the first days and weeks of a baby's life can make a real difference by helping parents cope with the stress of crying. This has been proven to reduce the number of serious injuries and deaths in babies. The aim is to acquaint all new parents with the ICON message, particularly targeting the male partner/carer involved, and signpost them to resources they can access when they need help. Please print the attached leaflet and add local contact information in the appropriate area. The proposed actions are:},
author = {{NHS England}},
file = {:Users/juandp77/Dropbox/references/Nhs/Clinical guide for the management of Rheumatology patients during the coronavirus pandemic - NHS England - 2020.pdf:pdf},
journal = {Nhs},
number = {2},
pages = {1--16},
title = {{Clinical guide for the management of Rheumatology patients during the coronavirus pandemic}},
year = {2020}
}
@article{Catani2013,
abstract = {The frontal aslant tract is a direct pathway connecting Broca's region with the anterior cingulate and pre-supplementary motor area. This tract is left lateralized in right-handed subjects, suggesting a possible role in language. However, there are no previous studies that have reported an involvement of this tract in language disorders. In this study we used diffusion tractography to define the anatomy of the frontal aslant tract in relation to verbal fluency and grammar impairment in primary progressive aphasia. Thirty-five patients with primary progressive aphasia and 29 control subjects were recruited. Tractography was used to obtain indirect indices of microstructural organization of the frontal aslant tract. In addition, tractography analysis of the uncinate fasciculus, a tract associated with semantic processing deficits, was performed. Damage to the frontal aslant tract correlated with performance in verbal fluency as assessed by the Cinderella story test. Conversely, damage to the uncinate fasciculus correlated with deficits in semantic processing as assessed by the Peabody Picture Vocabulary Test. Neither tract correlated with grammatical or repetition deficits. Significant group differences were found in the frontal aslant tract of patients with the non-fluent/agrammatic variant and in the uncinate fasciculus of patients with the semantic variant. These findings indicate that degeneration of the frontal aslant tract underlies verbal fluency deficits in primary progressive aphasia and further confirm the role of the uncinate fasciculus in semantic processing. The lack of correlation between damage to the frontal aslant tract and grammar deficits suggests that verbal fluency and grammar processing rely on distinct anatomical networks.},
author = {Catani, Marco and Mesulam, Marsel M. and Jakobsen, Estrid and Malik, Farah and Martersteck, Adam and Wieneke, Christina and Thompson, Cynthia K. and {Thiebaut De Schotten}, Michel and Dell'Acqua, Flavio and Weintraub, Sandra and Rogalski, Emily},
doi = {10.1093/brain/awt163},
file = {:Users/juandp77/Dropbox/references/Brain/A novel frontal pathway underlies verbal fluency in primary progressive aphasia - Catani et al. - 2013.pdf:pdf},
isbn = {1460-2156 (Electronic)$\backslash$n0006-8950 (Linking)},
issn = {00068950},
journal = {Brain},
keywords = {Aphasia,Dementia,Freesurfer,Frontal aslant tract,Language,Tractography,White matter},
number = {8},
pages = {2619--2628},
pmid = {23820597},
title = {{A novel frontal pathway underlies verbal fluency in primary progressive aphasia}},
volume = {136},
year = {2013}
}
@misc{Benamor1998,
abstract = {We report a case of spontaneous intracranial hypotension (SIH) that was investigated using cranial MRI and radionuclide cisternography. Radionuclide imaging was remarkable, showing direct signs of diffuse asymmetric leakage and indirect signs of cerebrospinal fluid (CSF) hypotension consisting of slow CSF circulation to the convexity and rapid appearance of urinary bladder activity. The MRI appearance was also suggestive of SIH, with diffuse meningeal enhancement. Treatment with autologous blood injection at the level of the radionuclide spinal leakage was useful, resulting in disappearance of SIH symptoms.},
author = {Benamor, M and Tainturier, C and Graveleau, P and Pierot, L},
booktitle = {Clinical nuclear medicine},
doi = {10.1097/00003072-199803000-00003},
issn = {0363-9762},
number = {3},
pages = {150--151},
pmid = {9509927},
title = {{Radionuclide cisternography in spontaneous intracranial hypotension.}},
volume = {23},
year = {1998}
}
@article{Hemphill2015a,
abstract = {PURPOSE: The aim of this guideline is to present current and comprehensive recommendations for the diagnosis and treatment of spontaneous intracerebral hemorrhage. METHODS: A formal literature search of PubMed was performed through the end of August 2013. The writing committee met by teleconference to discuss narrative text and recommendations. Recommendations follow the American Heart Association/American Stroke Association methods of classifying the level of certainty of the treatment effect and the class of evidence. Prerelease review of the draft guideline was performed by 6 expert peer reviewers and by the members of the Stroke Council Scientific Oversight Committee and Stroke Council Leadership Committee. RESULTS: Evidence-based guidelines are presented for the care of patients with acute intracerebral hemorrhage. Topics focused on diagnosis, management of coagulopathy and blood pressure, prevention and control of secondary brain injury and intracranial pressure, the role of surgery, outcome prediction, rehabilitation, secondary prevention, and future considerations. Results of new phase 3 trials were incorporated. CONCLUSIONS: Intracerebral hemorrhage remains a serious condition for which early aggressive care is warranted. These guidelines provide a framework for goal-directed treatment of the patient with intracerebral hemorrhage.},
archivePrefix = {arXiv},
arxivId = {15334406},
author = {Hemphill, J. Claude and Greenberg, Steven M. and Anderson, Craig S. and Becker, Kyra and Bendok, Bernard R. and Cushman, Mary and Fung, Gordon L. and Goldstein, Joshua N. and MacDonald, R. Loch and Mitchell, Pamela H. and Scott, Phillip A. and Selim, Magdy H. and Woo, Daniel},
doi = {10.1161/STR.0000000000000069},
eprint = {15334406},
file = {:Users/juandp77/Dropbox/references/Stroke/Guidelines for the Management of Spontaneous Intracerebral Hemorrhage A Guideline for Healthcare Professionals from the American Hear(2).pdf:pdf},
isbn = {0039249915244628},
issn = {15244628},
journal = {Stroke},
keywords = {AHA Scientific Statements,blood pressure,coagulopathy,diagnosis,intracerebral hemorrhage,intraventricular hemorrhage,surgery,treatment},
number = {7},
pages = {2032--2060},
pmid = {26022637},
title = {{Guidelines for the Management of Spontaneous Intracerebral Hemorrhage: A Guideline for Healthcare Professionals from the American Heart Association/American Stroke Association}},
volume = {46},
year = {2015}
}
@article{Robertson2020a,
author = {Robertson, Faith C. and Esene, Ignatius N. and Kolias, Angelos G. and Khan, Tariq and Rosseau, Gail and Gormley, William B. and Park, Kee B. and Broekman, Marike L.D. and Rosenfeld, Jeffrey and Balak, Naci and Ammar, Ahmed and Tisel, Magnus and Haglund, Michael and Smith, Timothy and Mendez, Ivar and Brennum, Jannick and Honeybul, Stephen and Matsumara, Akira and Muneza, Severien and Rubiano, Andres and Kamalo, Patrick and Fieggen, Graham and Misra, Basant and Bolles, Gene and Adelson, David and Dempsey, Robert and Hutchinson, Peter and Nikova, Alexandrina and Ghazala, Osama and Buno, Elubabor and Bhattacharjee, Shibashish and Iizuka, Takahiro and Abdullah, Jafri Malin and Chaurasia, Bipin and Morgan, Eghosa and Alcedo-Guardia, Rodolfo E. and Lucena, Lynne Lourdes N. and Oktay, Kadir and AbdAllah, Omar Ibrahim and Saihi, Ahlem and Abdeldjalil, Gacem and Asmaa, Mahi and Yampolsky, Claudio and Saladino, Laura P. and Mannara, Francisco and Sachdev, Sonal and Price, Benjamin and Joris, Vincent and {Adeniran Bankole}, Nourou Dine and Carrasco, Edgar M. and Hodzic, Mirsad and {de Sousa Porto}, Marcos Wagner and Amorim, Robson and Maldonado, Igor Lima and Yves, Bizoza and Suarez, Gonzalo and Constanzo, Felipe and {Valdeblanquez Atencio}, Johanna Cecilia and {Ruiz Mora}, Karen Alexa and {Rodriguez Gil}, Juan Manuel and Paraskeva, Kiriakos and Egemen, Emrah and Ngamasata, Trevcsor and Ntalaja, Jeff and Beltchika, Antoine and Ntsambi, Glennie and Dunia, Goertz Mirenge and Taha, Mahmoud M. and Arnaout, Mohamed and Kirollos, Ramez and Kassem, Mohamed and Elwardany, Omar and Negida, Ahmed and Dolango, Birhanu and Aseged, Mikael and Mldie, Alemu Adise and Laeke, Tsegazeab and Aklilu, Abenezer and Adefris, Esayas and Luoto, Teemu and Behnam, Rezai Jahromi and {De Schlichting}, Emmanuel and Nassim, Bougaci and Bourdillon, Pierre and Stienen, Martin N. and Lackermair, Stephan and Schmidt, Franziska Anna and Konczalla, Juergen and Holzgreve, Adrien and Sagerer, Andre and Weinert, Dieter M. and Kumi, Paulette and McLean, Aaron Lawson and Loan, James and Cahill, Julian and Dockrell, Simon and Afshari, Fardad T. and May, Paul and Honeybul, Stephen and Athanasiou, Alkinoos and Papadopoulos, Steven and Espinoza, Edroulfo-Georgios and Chatzisotiriou, Athanasios and Vlachogiannis, Pavlos and Karabatsou, Konstantina and Paschalis, Thanasis and Tsitsipanis, Christos and {Longo Calderan}, Gabriel Mauricio and Leiva, Ronny and Deora, Harsh and Mukkamala, Sreenivas and Batra, Dipesh and Sukumaran, Arvind and Parmar, Kanishk and Bahl, Anuj and Agrawal, Amit and Dev, Nirankar and Thakur, Nikhil and Behari, Sanjay and Yandrapati, Chandrasekhar B.V.K. and Bhoot, Ritesh and Bhatt, Pragnesh and Bhaumik, Uday and Agrawal, Manish and Thomas, Antony and Chandrappa, Harish and Mathur, Ankit and Wahjoepramono, Petra and Oswari, Selfy and Al-Mahfoudh, Rafid and Alnaji, Abbas and Abuhadrous, Nidal and Jarad, Bakr Abo and Nour, Ibrahim and Cohen-Inbar, Or and Colasanti, Roberto and Conti, Alfredo and Raffa, Giovanni and Castrioto, Corrado and Baccanelli, Matteo M. and Tomasi, Santino Ottavio and Zoli, Matteo and Veroni, Andrea and {Di Cristofori}, Andrea and Giannachi, Luigi and Lippa, Laura and Sgubin, Donatella and Broggi, Morgan and Barbato, Marcello and Restelli, Francesco and Ganau, Mario and Taddei, Graziano and Albadawi, Hamzeh and Salameh, Mohammed and Gulmira, Madieyva and Lashhab, Muffaq and {El Gaddafi}, Walid and Altoumi, Mohammad and Manvinder, S.M. and Kanesen, Davendran and Teo, Mario and Sriram, Prabu Rau and Zamri, Sarah Atiqah M. and Vinodh, Vayara Perumall and Denou, Moussa and Melhaoui, Adyl and Outani, Oumaima and Boutarbouch, Mahjouba and Gretschel, Armin and Yadav, Pradhumna and Karmacharya, Balgopal and Incekara, Fatih and den Boogert, Hugo and Lopez, Buccket Argvoello and Amadou, Hassane Ali and Sale, Danjuma and Bello, Sanusi and Edward, Poluyi and Ukachukwu, Alvan-Emeka and Nwaribe, Evaristus and Aniaku, Ikechukwu and Ndajiwo, Aliyu Baba and Ayodele, Olabamidele and Bot, Gyang Markus and {Ndubuisu Achebe}, Sunday David and Jamal, Bakht and Tariq, Muhammad and Farooq, Ghulam and Khan, Tariq and Khan, Danyal Zaman and Khizar, Ahtesham and Hussain, Zahid and Nazir, Anisa and Gonzales-Portillo, Marco and Bautista, Jhosep Silvestre and Torres, Roland A. and Javier-Lizan, Abigail and de los Santos, Isagani Jodl G. and Morais, Nuno and Dias, Lydia and Noronha, Carolina and Silva, Jovelo Monteiro and Seromenho-Santos, Alexandra and Lozanche, Kiril and Negoi, Ionut and Tascu, Alexandru and Kozyrev, Danil A. and Nkeshimana, Menelas and Karekezi, Claire and Ndayishyigikiye, Marcel Didier and Alabbass, Faisal and Farrash, Faisal and Alhazmi, Rawan and Golubovic, Jagos and Lepif{\'{a}}, Milan and Ilif{\'{a}}, Rosanda and Stanimirovif{\'{a}}, Aleksandar and Garcia-Garcia, Sergio and {Rodriguez Arias}, Carlos A. and Lau, Ruth and Delgado-Fernandez, Juan and Arraez, Miguel A. and Mateos, C. Fernandez and {Castano Leon}, Ana M. and Wadanamby, Saman and Bervini, David and Shabani, Hamisi K. and Limpastan, Kriengsak and Ayadi, Khalil and Sencer, Altay and Yalcinkaya, Ali and Eren, Elif and Balak, Naci and Basaran, Recep and Gokoglu, Abdulkerim and Mykola, Vyval and Tayong, Felicita and Rosseau, Gail and Zuccarello, Mario and Quinsey, Carolyn and Dewan, Michael C. and Young, Paul H. and Laws, Edward and Rock, Jack and Kurland, David B. and Muh, Carrie R. and {Delgado Aguilar}, Eri Dario and Burns, Kenneth and Low, Jacob and Keogh, Conor and Uff, Chris and Spina, Alfio and Alelyani, Fayez},
doi = {10.1016/j.wnsx.2019.100060},
file = {:Users/juandp77/Dropbox/references/World Neurosurgery X/Global Perspectives on Task Shifting and Task Sharing in Neurosurgery - Robertson et al. - 2020.pdf:pdf},
issn = {25901397},
journal = {World Neurosurgery: X},
month = {apr},
pages = {100060},
title = {{Global Perspectives on Task Shifting and Task Sharing in Neurosurgery}},
url = {https://linkinghub.elsevier.com/retrieve/pii/S2590139719301012},
volume = {6},
year = {2020}
}
@article{Tam2010,
abstract = {Background and importance: Spinal cord compression may induce cortical reorganization. This study follows a patient with cervical spondylotic myelopathy to investigate changes in cortical activation before and after decompressive surgery. The relationship with functional recovery is also described. Clinical presentation: A 37-year-old right-hand-dominant man presented a 1-month history of rapidly worsening right-hand clumsiness, right-sided hemiparesis, and gait difficulties. Physical examination confirmed severe right-sided weakness, impaired dexterity, hyperreflexia, and wide-based gait. The patient underwent blood oxygenation level-dependent functional magnetic resonance imaging at 4 T. Images were obtained before and 6 months after an anterior cervical discectomy with insertion of an artificial disk. Blood oxygenation level-dependent functional magnetic resonance imaging was used to detect changes in cortical activation over time during a finger-tapping (motor) paradigm. Improvement in clinical function was recorded with validated clinical tools, including the Japanese Orthopedic Association scale for cervical spondylotic myelopathy, the Nurick neurological function score, and the Neck Disability Index, along with clinical examination. Conclusion: After decompressive cervical spine surgery in a patient with cervical spondylotic myelopathy, functional magnetic resonance imaging detected increased cortical activation in the primary motor cortex during finger tapping. These changes occurred concomitantly with improvement in motor function. Upper-and lower-extremity motor subscores of the Japanese Orthopedic Association scale demonstrated 40{\%} and 43{\%} improvement, respectively. These observations suggest that cortical reorganization or recruitment may accompany the recovery of function after spinal cord injury. {\textcopyright} 2010 by the Congress of Neurological Surgeons.},
author = {Tam, Samantha and Barry, Robert L. and Bartha, Robert and Duggal, Neil},
doi = {10.1227/01.NEU.0000374848.86299.17},
file = {:Users/juandp77/Dropbox/references/Neurosurgery/Changes in functional magnetic resonance imaging cortical activation after decompression of cervical spondylosis Case report - Tam et al.pdf:pdf},
isbn = {1524-4040},
issn = {0148396X},
journal = {Neurosurgery},
keywords = {Cerebral cortical activation,Cervical spondylosis,Decompression,Functional magnetic resonance imaging},
number = {3},
pages = {2--6},
pmid = {20657323},
title = {{Changes in functional magnetic resonance imaging cortical activation after decompression of cervical spondylosis: Case report}},
volume = {67},
year = {2010}
}
@article{Komotar2005a,
abstract = {OBJECTIVE: Cerebrospinal fluid hypovolemia resulting in postural headaches is a well-known clinical entity, but severe forms of cerebrospinal fluid hypovolemia with altered mental status and signs of transtentorial herniation ("brain sag") have rarely been reported. This article describes the clinical features of brain sag after craniotomy in an attempt to increase recognition of this syndrome. METHODS: Between April 2001 and January 2003, 220 consecutive patients with subarachnoid hemorrhage were prospectively enrolled in the Columbia Subarachnoid Hemorrhage Outcomes Project; 137 underwent craniotomy for aneurysm clipping. Among these patients, the diagnosis of brain sag was made when all three of the following criteria were present: clinical signs of transtentorial herniation, head computed tomographic scans revealing effacement of the basal cisterns with an oblong brainstem, and improvement of symptoms after placement of the patient in the Trendelenburg position (-15 to -30 degrees). For each patient, the symptoms, clinical course, and subsequent response to treatment were characterized. In addition, brainstem dimensions were measured on computed tomographic scans taken before, during, and after resolution of brain sag. A "sag ratio" was generated for these time points by dividing the maximum anteroposterior distance by the maximum bipeduncular distance. RESULTS: Eleven (8.0{\%}) of 137 aneurysmal subarachnoid hemorrhage patients treated by craniotomy and an intraoperative spinal drain met the criteria for brain sag. Signs of transtentorial herniation developed most commonly between 2 and 4 days postoperatively. Pupillary asymmetry was noted in 10 (91.0{\%}) of 11 patients, whereas the other patient demonstrated extensor posturing. The Trendelenburg position reversed the symptoms in all patients. The mean sag ratios before, during, and after resolution of brain sag were 0.91 +/- 0.03 (mean +/- standard error), 1.18 +/- 0.03, and 0.91 +/- 0.03, respectively. This represented a 30.9{\%} elongation of the brainstem during sag (P {\textless} 0.001) and a 23.6{\%} change back to baseline after resolution of the syndrome (P {\textless} 0.002). There was no significant difference between the presag and postsag ratios. CONCLUSION: Severe cerebrospinal fluid hypovolemia after craniotomy may produce a dramatic herniation syndrome that is completely reversed by the Trendelenburg position. Brain sag should be included in the differential diagnosis for acute postoperative clinical deterioration in this patient population.},
author = {Komotar, Ricardo J. and Mocco, J. and Ransom, Evan R. and Mack, William J. and Zacharia, Brad E. and Wilson, David A. and Naidech, Andrew M. and McKhann, Guy M. and Mayer, Stephan A. and Fitzsimmons, Brian Fred M and Connolly, E. Sander},
doi = {10.1227/01.NEU.0000166661.96546.33},
isbn = {1524-4040 (Electronic)$\backslash$r0148-396X (Linking)},
issn = {0148396X},
journal = {Neurosurgery},
keywords = {Brain sag,Cerebrospinal fluid,Craniotomy,Herniation,Hypovolemia,Lumbar drain},
number = {2},
pages = {286--290},
pmid = {16094157},
title = {{Herniation secondary to critical postcraniotomy cerebrospinal fluid hypovolemia}},
volume = {57},
year = {2005}
}
@article{Backous2008,
abstract = {Counseling patients who are diagnosed with vestibular schwannomas, formerly known as acoustic neuromas, can be challenging. The health care provider has the responsibility to explain, in understandable language, to the patient or legal representative the proposed treatment options, risks and complications associated with each form of treatment, and alternatives to treatment, including no therapy. Patients should be encouraged to gather information before making a treatment decision. For the physicians managing these patients, information should be delivered in a balanced way to ensure patient understanding of their options leading to adequate informed consent. {\textcopyright} 2008 Elsevier Inc. All rights reserved.},
author = {Backous, Douglas D. and Pham, Huong T.},
doi = {10.1016/j.nec.2008.02.004},
file = {:Users/juandp77/SynologyDrive/references/Neurosurgery Clinics of North America/Guiding Patients Through the Choices for Treating Vestibular Schwannomas Balancing Options and Ensuring Informed Consent - Backous, Pham.pdf:pdf},
issn = {10423680},
journal = {Neurosurgery Clinics of North America},
number = {2},
pages = {379--392},
pmid = {18534346},
title = {{Guiding Patients Through the Choices for Treating Vestibular Schwannomas: Balancing Options and Ensuring Informed Consent}},
volume = {19},
year = {2008}
}
@article{Bartolomei2017,
abstract = {Epileptogenic networks are defined by the brain regions involved in the production and propagation of epileptic activities. In this review we describe the historical, methodologic, and conceptual bases of this model in the analysis of electrophysiologic intracerebral recordings. In the context of epilepsy surgery, the determination of cerebral regions producing seizures (i.e., the “epileptogenic zone”) is a crucial objec- tive. In contrast with a traditional focal vision of focal drug-resistant epilepsies, the concept of epileptogenic networks has been progressively introduced as a model bet- ter able to describe the complexity of seizure dynamics and realistically describe the distribution of epileptogenic anomalies in the brain. The concept of epileptogenic networks is historically linked to the development of the stereoelectroencephalogra- phy (SEEG) method and subsequent introduction of means of quantifying the recorded signals. Seizures, and preictal and interictal discharges produce clear pat- terns on SEEG. These patterns can be analyzed utilizing signal analysis methods that quantify high-frequency oscillations or changes in functional connectivity. Dramatic changes in SEEG brain connectivity can be described during seizure genesis and prop- agation within cortical and subcortical regions, associated with the production of dif- ferent patterns of seizure semiology. The interictal state is characterized by networks generating abnormal activities (interictal spikes) and also by modified func- tional properties. The introduction of novel approaches to large-scale modeling of these networks offers new methods in the goal of better predicting the effects of epi- lepsy surgery. The epileptogenic network concept is a key factor in identifying the anatomic distribution of the epileptogenic process, which is particularly important in the context of epilepsy surgery.},
author = {Bartolomei, Fabrice and Lagarde, Stanislas and Wendling, Fabrice and Mcgonigal, Aileen and Jirsa, Viktor and Guye, Maxime and B{\'{e}}nar, Christian},
doi = {10.1111/epi.13791},
file = {:Users/juandp77/Dropbox/references/Epilepsia/Defining epileptogenic networks Contribution of SEEG and signal analysis - Bartolomei et al. - 2017.pdf:pdf},
issn = {00139580},
journal = {Epilepsia},
keywords = {Brain networks,Focal epilepsies,Functional connectivity,Signal processing,Stereoelectroencephalography},
pages = {1--17},
title = {{Defining epileptogenic networks : Contribution of SEEG and signal analysis}},
year = {2017}
}
@article{Juttler2014,
abstract = {BACKGROUND: Early decompressive hemicraniectomy reduces mortality without increasing the risk of very severe disability among patients 60 years of age or younger with complete or subtotal space-occupying middle-cerebral-artery infarction. Its benefit in older patients is uncertain. METHODS: We randomly assigned 112 patients 61 years of age or older (median, 70 years; range, 61 to 82) with malignant middle-cerebral-artery infarction to either conservative treatment in the intensive care unit (the control group) or hemicraniectomy (the hemicraniectomy group); assignments were made within 48 hours after the onset of symptoms. The primary end point was survival without severe disability (defined by a score of 0 to 4 on the modified Rankin scale, which ranges from 0 [no symptoms] to 6 [death]) 6 months after randomization. RESULTS: Hemicraniectomy improved the primary outcome; the proportion of patients who survived without severe disability was 38{\%} in the hemicraniectomy group, as compared with 18{\%} in the control group (odds ratio, 2.91; 95{\%} confidence interval, 1.06 to 7.49; P=0.04). This difference resulted from lower mortality in the surgery group (33{\%} vs. 70{\%}). No patients had a modified Rankin scale score of 0 to 2 (survival with no disability or slight disability); 7{\%} of patients in the surgery group and 3{\%} of patients in the control group had a score of 3 (moderate disability); 32{\%} and 15{\%}, respectively, had a score of 4 (moderately severe disability [requirement for assistance with most bodily needs]); and 28{\%} and 13{\%}, respectively, had a score of 5 (severe disability). Infections were more frequent in the hemicraniectomy group, and herniation was more frequent in the control group. CONCLUSIONS: Hemicraniectomy increased survival without severe disability among patients 61 years of age or older with a malignant middle-cerebral-artery infarction. The majority of survivors required assistance with most bodily needs. (Funded by the Deutsche Forschungsgemeinschaft; DESTINY II Current Controlled Trials number, ISRCTN21702227.).},
author = {J{\"{u}}ttler, E and Unterberg, a and Woitzik, J and {Et Al.}},
doi = {10.1056/NEJMoa1311367},
file = {:Users/juandp77/Dropbox/references/The New England journal of medicine/Hemicraniectomy in Older Patients with Extensive Middle-Cerebral-Artery Stroke - J{\"{u}}ttler et al. - 2014.pdf:pdf},
isbn = {4962215663},
issn = {1533-4406},
journal = {The New England journal of medicine},
keywords = {80 and over,Aged,Craniotomy,Disabled Persons,Female,Humans,Infarction,Intensive Care Units,Male,Middle Aged,Middle Cerebral Artery,Prospective Studies,Survival Rate},
number = {12},
pages = {1091--100},
pmid = {24645942},
title = {{Hemicraniectomy in Older Patients with Extensive Middle-Cerebral-Artery Stroke}},
url = {http://www.ncbi.nlm.nih.gov/pubmed/24645942{\%}5Cnhttp://www.nejm.org/doi/pdf/10.1056/NEJMoa1311367},
volume = {370},
year = {2014}
}
@article{Govind2016,
author = {Govind, Mangal and Radheyshyam, Mittal and Achal, Sharma and Ashok, Gandhi},
file = {:Users/juandp77/Dropbox/references/Romanian Neurosurgery/Intradural Extramedullary Spinal cord Tumors A Retrospective Study at Tertiary Referral Hospital - Govind et al. - 2016.pdf:pdf},
journal = {Romanian Neurosurgery},
keywords = {idem,intradural extramedullary tumors,spinal cord,surgical outcomes},
number = {1},
pages = {106--112},
title = {{Intradural Extramedullary Spinal cord Tumors : A Retrospective Study at Tertiary Referral Hospital}},
volume = {XXX},
year = {2016}
}
@article{Ferrante1992,
abstract = {Of the 62 patients with intramedullary spinal cord ependymoma treated surgically at our Neurosurgery Division between January 1951 and December 1990 45 had a follow-up of at least 3 years and the longest 30 years. The 28 conus-cauda equina-filum ependymomas operated during the same period are not considered in this study. An analysis of our cases and of the larger published series shows that favourable prognostic factors, apart of course from total tumour removal, which is now usually possible, are a site below the high cervical segments and a mild pre-operative symptom pattern. Patient age at diagnosis, tumour size and "low dose" ({\textless} 40 Gy) radiotherapy seem to have no influence on the prognosis. Aggressive surgical removal is the treatment of choice and also for long-term recurrence.},
author = {Ferrante, L and Mastronardi, L and Celli, P and Lunardi, P and Acqui, M and Fortuna, A},
issn = {0001-6268 (Print)},
journal = {Acta neurochirurgica},
keywords = {Adolescent,Adult,Aged,Child,Child, Preschool,Combined Modality Therapy,Ependymoma,Female,Follow-Up Studies,Humans,Magnetic Resonance Imaging,Male,Middle Aged,Neoplasm Recurrence, Local,Neurologic Examination,Reoperation,Retrospective Studies,Spinal Cord Neoplasms,diagnosis,radiotherapy,surgery},
number = {1-4},
pages = {74--79},
pmid = {1481757},
title = {{Intramedullary spinal cord ependymomas--a study of 45 cases with long-term follow-up.}},
volume = {119},
year = {1992}
}
@article{Krieg2017,
abstract = {{\textcopyright} 2017, Springer-Verlag Wien. Introduction: Navigated transcranial magnetic stimulation (nTMS) is increasingly used for preoperative mapping of motor function, and clinical evidence for its benefit for brain tumor patients is accumulating. In respect to language mapping with repetitive nTMS, literature reports have yielded variable results, and it is currently not routinely performed for presurgical language localization. The aim of this project is to define a common protocol for nTMS motor and language mapping to standardize its neurosurgical application and increase its clinical value. Methods: The nTMS workshop group, consisting of highly experienced nTMS users with experience of more than 1500 preoperative nTMS examinations, met in Helsinki in January 2016 for thorough discussions of current evidence and personal experiences with the goal to recommend a standardized protocol for neurosurgical applications. Results: nTMS motor mapping is a reliable and clinically validated tool to identify functional areas belonging to both normal and lesioned primary motor cortex. In contrast, this is less clear for language-eloquent cortical areas identified by nTMS. The user group agreed on a core protocol, which enables comparison of results between centers and has an excellent safety profile. Recommendations for nTMS motor and language mapping protocols and their optimal clinical integration are presented here. Conclusion: At present, the expert panel recommends nTMS motor mapping in routine neurosurgical practice, as it has a sufficient level of evidence supporting its reliability. The panel recommends that nTMS language mapping be used in the framework of clinical studies to continue refinement of its protocol and increase reliability.},
author = {Krieg, Sandro M. and Lioumis, Pantelis and M{\"{a}}kel{\"{a}}, Jyrki P. and Wilenius, Juha and Karhu, Jari and Hannula, Henri and Savolainen, Petri and Lucas, Carolin Weiss and Seidel, Kathleen and Laakso, Aki and Islam, Mominul and Vaalto, Selja and Lehtinen, Henri and Vitikainen, Anne Mari and Tarapore, Phiroz E. and Picht, Thomas},
doi = {10.1007/s00701-017-3187-z},
file = {:Users/juandp77/Dropbox/references/Acta Neurochirurgica/Protocol for motor and language mapping by navigated TMS in patients and healthy volunteers workshop report - Krieg et al. - 2017.pdf:pdf},
issn = {09420940},
journal = {Acta Neurochirurgica},
keywords = {Brain tumor,Epilepsy surgery,Language,Motor,Preoperative mapping,Transcranial magnetic stimulation},
number = {7},
pages = {1187--1195},
publisher = {Acta Neurochirurgica},
title = {{Protocol for motor and language mapping by navigated TMS in patients and healthy volunteers; workshop report}},
volume = {159},
year = {2017}
}
@article{Iwasaki2019,
author = {Iwasaki, Motoyuki and Yokohama, Takumi and Oura, Daisuke and Furuya, Shou and Niiya, Yoshimasa and Okuaki, Tomoyuki},
doi = {10.1016/j.wnsx.2019.100056},
file = {:Users/juandp77/Dropbox/references/World Neurosurgery X/Decreased Value of Highly Accurate Fractional Anisotropy Using 3-Tesla Zoom Diffusion Tensor Imaging after Decompressive Surgery in.pdf:pdf},
issn = {25901397},
journal = {World Neurosurgery: X},
keywords = {- diffusion tensor imaging,- fractional anisotropy,cervical degenerative spondylosis},
pages = {100056},
publisher = {Elsevier Inc},
title = {{Decreased Value of Highly Accurate Fractional Anisotropy Using 3-Tesla Zoom Diffusion Tensor Imaging after Decompressive Surgery in Patients with Cervical Spondylotic Myelopathy: “Aligned Fibers Effect”}},
url = {https://doi.org/10.1016/j.wnsx.2019.100056},
volume = {4},
year = {2019}
}
@article{Yong2013,
author = {Yong, Ki and Jang, Na Ji-hye and Youn, Ji-youn Sung and Kim, Wha},
file = {:Users/juandp77/Dropbox/references/Unknown/Actinomycotic Brain Abscess Developed 10 Years after Head Trauma - Yong et al. - 2013.pdf:pdf},
pages = {82--85},
title = {{Actinomycotic Brain Abscess Developed 10 Years after Head Trauma}},
year = {2013}
}
@article{Jussen2016,
abstract = {Objective: To explore plasticity in patients scheduled for extra-intracranial bypass surgery due to unilateral symptomatic occlusive cerebrovascular disease via navigated transcranial magnetic stimulation. Methods: In this observational study patients were allocated to different sub-studies and examined before and 3 months after operation. A) Corticospinal excitability was determined via identification of the resting motor threshold. B) Intracortical inhibition and facilitation were tested by paired pulse transcranial magnetic stimulation. C) Area of cortical representation of the first dorsal interosseous muscle was identified. Results: A) Resting motor thresholds were higher in the affected hemispheres (AH) with impaired cerebrovascular reserve capacity compared to the unaffected hemispheres (UH) (45.7 ± 2.2{\%} compared to 39.2 ± 1.4{\%}, n=39, p{\textless}0.05). Reduced excitability normalized 3 months after revascularization (51 ± 2.6{\%} → 45 ± 1.9{\%}, n=21, p{\textless}0.05). B) In paired pulse paradigms, there was a motor disinhibition in the operated hemispheres. C) There was a reduction of the cortical representation areas of the first dorsal interosseous muscle (2.3 ± 0.5cm2 → 0.9 ± 0.6cm2, n=9, p {\textless}0.05) after operation. Conclusions: Our data demonstrate a reversibly impaired motorcortical function in the chronically ischemic brain. In carefully selected patients cerebral revascularization leads to improved motor output indicated by a lower resting motor threshold, intracortical disinhibition, and more focused motorcortical representation.},
author = {Jussen, Daniel and Zdunczyk, Anna and Schmidt, Sein and R{\"{o}}sler, Judith and Buchert, Ralph and Julkunen, Petro and Karhu, Jari and Brandt, Stephan and Picht, Thomas and Vajkoczy, Peter},
doi = {10.1212/WNL.0000000000002802},
file = {:Users/juandp77/Dropbox/references/Neurology/Motor plasticity after extra-intracranial bypass surgery in occlusive cerebrovascular disease - Jussen et al. - 2016.pdf:pdf},
isbn = {0028-3878},
issn = {1526632X},
journal = {Neurology},
number = {1},
pages = {27--35},
pmid = {27281529},
title = {{Motor plasticity after extra-intracranial bypass surgery in occlusive cerebrovascular disease}},
volume = {87},
year = {2016}
}
@article{Bolger2007,
abstract = {Pedicle screw fixation has achieved significant popularity amongst spinal surgeons for both single and multi-level spinal fusion. Misplacement and pedicle cortical violation occurs in over 20{\{}{\%}{\}} of screw placement and can result in potential complications such as dysthesia, paraparesis or paraplegia. There have been many advances in techniques available for navigating through the pedicle; however, these techniques are not without drawbacks. A new electrical conductivity-measuring device, previously evaluated on the porcine model to detect the pedicle violation, was evaluated amongst nine European Hospitals to be used in conjunction with the methods currently used in that centre. This new device is based on two original principles; the device is integrated in the drilling or screwing tool. The technology allows real-time detection of perforation through two independent parameters, impedance variation and evoked muscle contractions. Data was collected twofold. Initially, the surgeon was given the device and a comparison was made between the devices ability to detect a breech and the surgeon's ability to detect one using his traditional methods of pedicle preparation. In the second module of the study, the surgeon was limited to using the electrical conductivity detection device as their sole guide to detect pedicle breaches. A comparison was made between the detection ability of the device and the other detection possibilities. Post-operative fine cut CT scanning was used to detect the pedicle breaches. Overall, the 11 trial surgeons performed a total of 521 pedicle drillings on 97 patients. Initially there were 147 drillings with 23 breaches detected. The detection rate of these breaches were 22/23 for the device compared to 10/23 by the surgeon. Over both parts of the study 64 breaches (12.3{\{}{\%}{\}}) were confirmed on post-operative CT imaging. The electrical conductivity detection device detected 63 of the 64 breaches (98.4{\{}{\%}{\}}). There was one false negative and four false positives. This gives the device an overall sensitivity of 98{\{}{\%}{\}} and specificity of 99{\{}{\%}{\}} for detecting a pedicle breach. The negative predictive value was 99.8{\{}{\%}{\}}, with a positive predictive value of 94{\{}{\%}{\}}. No adverse event was noted with the use of the electrical conductivity device. Electrical conductivity monitoring may provide a simple, safe and sensitive method of detecting pedicle breech during routine perforation of the pedicle, in the course of pedicle screw placement.},
author = {Bolger, Ciaran and Kelleher, Michael O. and McEvoy, Linda and Brayda-Bruno, M. and Kaelin, A. and Lazennec, J. Y. and {Le Huec}, J. C. and Logroscino, C. and Mata, P. and Moreta, P. and Saillant, G. and Zeller, R.},
doi = {10.1007/s00586-007-0409-8},
file = {:Users/juandp77/Dropbox/references/European Spine Journal/Electrical conductivity measurement A new technique to detect iatrogenic initial pedicle perforation - Bolger et al. - 2007.pdf:pdf},
isbn = {0940-6719 (Print)$\backslash$r0940-6719 (Linking)},
issn = {09406719},
journal = {European Spine Journal},
keywords = {Electrical conductivity measuring device,Impedance measuring device,PediGuard,Pedicle screws,Spine},
number = {11},
pages = {1919--1924},
pmid = {17602249},
title = {{Electrical conductivity measurement: A new technique to detect iatrogenic initial pedicle perforation}},
volume = {16},
year = {2007}
}
@article{Deftereos2015,
abstract = {Study Design: Case series. Objective: To compare transcranial magnetic stimulation (TMS) and magnetic resonance imaging (MRI) findings between patients who underwent surgery for cervical spondylotic myelopathy and those with spondylosis who were not operated upon, and to correlate these findings with clinical functionality at follow-up. Setting: Private practice. Methods: Of 16 consecutive patients with cervical spondylosis 8 underwent surgery (group I) and 8 were treated conservatively (group II). We compared TMS and MRI findings between these groups and we correlated central motor conduction times (CMCTs) and MRI-measured sagittal and parasagittal diameters of the spinal canal at baseline evaluation, with clinical functionality at 2-year follow-up. Results: Group I CMCTs at the lower limbs correlated significantly with modified-JoA 2 years post surgery (r=-0.71, P{\textless}0.05), but MRI-measured diameters did not. In group II baseline TMS was unrevealing, contrary to significant spinal stenosis disclosed by MRI. The condition of none of these patients deteriorated at 2 years. Conclusions: CMCTs at the lower limbs, but not cervical spinal canal diameters, correlate with long-term functional outcome following surgical or conservative treatment. Copyright {\textcopyright} 2015 International Spinal Cord Society All rights reserved.},
author = {Deftereos, S. N. and Kechagias, E. and Ioakeimidou, C. and Georgonikou, D.},
doi = {10.1038/sc.2014.220},
file = {:Users/juandp77/Dropbox/references/Spinal Cord/Transcranial magnetic stimulation but not MRI predicts long-term clinical status in cervical spondylosis A case series - Deftereos et al.pdf:pdf},
isbn = {1362-4393},
issn = {14765624},
journal = {Spinal Cord},
number = {July 2014},
pages = {S16--S18},
pmid = {25900284},
title = {{Transcranial magnetic stimulation but not MRI predicts long-term clinical status in cervical spondylosis: A case series}},
volume = {53},
year = {2015}
}
@article{Tang2013,
abstract = {The number of diffusion tensor imaging (DTI) studies regarding the human spine has considerably increased and it is challenging because of the spine's small size and artifacts associated with the most commonly used clinical imaging method. A novel segmentation method based on the reduced field-of-view (rFOV) DTI dataset is presented in cervical spinal canal cerebrospinal fluid, spinal cord grey matter and white matter classification in both healthy volunteers and patients with neuromyelitis optica (NMO) and multiple sclerosis (MS). Due to each channel based on high resolution rFOV DTI images providing complementary information on spinal tissue segmentation, we want to choose a different contribution map from multiple channel images. Via principal component analysis (PCA) and a hybrid diffusion filter with a continuous switch applied on fourteen channel features, eigen maps can be obtained and used for tissue segmentation based on the Bayesian discrimination method. Relative to segmentation by a pair of expert readers, all of the automated segmentation results in the experiment fall in the good segmentation area and performed well, giving an average segmentation accuracy of about 0.852 for cervical spinal cord grey matter in terms of volume overlap. Furthermore, this has important applications in defining more accurate human spinal cord tissue maps when fusing structural data with diffusion data. rFOV DTI and the proposed automatic segmentation outperform traditional manual segmentation methods in classifying MR cervical spinal images and might be potentially helpful for detecting cervical spine diseases in NMO and MS. {\textcopyright} 2013 Elsevier Inc.},
author = {Tang, Lihua and Wen, Ying and Zhou, Zhenyu and von Deneen, Karen M. and Huang, Dehui and Ma, Lin},
doi = {10.1016/j.mri.2013.07.003},
file = {:Users/juandp77/Dropbox/references/Magnetic Resonance Imaging/Reduced field-of-view DTI segmentation of cervical spine tissue - Tang et al. - 2013.pdf:pdf},
issn = {0730725X},
journal = {Magnetic Resonance Imaging},
keywords = {Cervical spine,DTI,Reduced field-of-view,Segmentation},
number = {9},
pages = {1507--1514},
pmid = {23993792},
publisher = {Elsevier Inc.},
title = {{Reduced field-of-view DTI segmentation of cervical spine tissue}},
url = {http://dx.doi.org/10.1016/j.mri.2013.07.003},
volume = {31},
year = {2013}
}
@article{Fedorov2012,
abstract = {Quantitative analysis has tremendous but mostly unrealized potential in healthcare to support objective and accurate interpretation of the clinical imaging. In 2008, the National Cancer Institute began building the Quantitative Imaging Network (QIN) initiative with the goal of advancing quantitative imaging in the context of personalized therapy and evaluation of treatment response. Computerized analysis is an important component contributing to reproducibility and efficiency of the quantitative imaging techniques. The success of quantitative imaging is contingent on robust analysis methods and software tools to bring these methods from bench to bedside. 3D Slicer is a free open-source software application for medical image computing. As a clinical research tool, 3D Slicer is similar to a radiology workstation that supports versatile visualizations but also provides advanced functionality such as automated segmentation and registration for a variety of application domains. Unlike a typical radiology workstation, 3D Slicer is free and is not tied to specific hardware. As a programming platform, 3D Slicer facilitates translation and evaluation of the new quantitative methods by allowing the biomedical researcher to focus on the implementation of the algorithm and providing abstractions for the common tasks of data communication, visualization and user interface development. Compared to other tools that provide aspects of this functionality, 3D Slicer is fully open source and can be readily extended and redistributed. In addition, 3D Slicer is designed to facilitate the development of new functionality in the form of 3D Slicer extensions. In this paper, we present an overview of 3D Slicer as a platform for prototyping, development and evaluation of image analysis tools for clinical research applications. To illustrate the utility of the platform in the scope of QIN, we discuss several use cases of 3D Slicer by the existing QIN teams, and we elaborate on the future directions that can further facilitate development and validation of imaging biomarkers using 3D Slicer.Copyright {\textcopyright} 2012 Elsevier Inc. All rights reserved.},
author = {Fedorov, Andrey and Beichel, Reinhard and Kalphaty-Cramer, Jayashree and Finet, Julien and Fillion-Robbin, J-C and Pujol, Sonia and Bauer, Christian and Jennings, Dominique and Fennessy, Fiona and Sonka, Milan and Buatti, John and Aylward, Stephen and Miller, James V. and Pieper, Steve and Kikinis, Ron},
doi = {10.1016/j.mri.2012.05.001.3D},
file = {:Users/juandp77/Dropbox/references/Magnetic resonance imaging/3D slicers as an image computing platform for thw quantitative imaging network - Fedorov et al. - 2012.pdf:pdf},
issn = {1873-5894},
journal = {Magnetic resonance imaging},
number = {9},
pages = {1323--1341},
title = {{3D slicers as an image computing platform for thw quantitative imaging network}},
volume = {30},
year = {2012}
}
@article{Fehlings2017,
abstract = {Acute spinal cord injury (SCI) is a traumatic event that results in disturbances to normal sensory, motor, or autonomic function and ultimately affects a patient's physical, psychological, and social well-being. The management of patients with SCI has drastically evolved over the past century as a result of increasing knowledge on injury mechanisms, disease pathophysiology, and the role of surgery. There still, however, remain controversial areas surrounding available management strategies for the treatment of SCI, including the use of corticosteroids such as methylprednisolone sodium succinate, the optimal timing of surgical intervention, the type and timing of anticoagulation prophylaxis, the role of magnetic resonance imaging, and the type and timing of rehabilitation. This lack of consensus has prevented the standardization of care across treatment centers and among the various disciplines that encounter patients with SCI. The objective of this guideline is to form evidence-based recommendations for these areas of controversy and outline how to best manage patients with SCI. The ultimate goal of these guidelines is to improve outcomes and reduce morbidity in patients with SCI by promoting standardization of care and encouraging clinicians to make evidence-informed decisions.},
author = {Fehlings, Michael G. and Tetreault, Lindsay A. and Wilson, Jefferson R. and Kwon, Brian K. and Burns, Anthony S. and Martin, Allan R. and Hawryluk, Gregory and Harrop, James S.},
doi = {10.1177/2192568217703387},
file = {:Users/juandp77/Dropbox/references/Global Spine Journal/A Clinical Practice Guideline for the Management of Acute Spinal Cord Injury Introduction, Rationale, and Scope - Fehlings et al. - 2017.pdf:pdf},
issn = {21925690},
journal = {Global Spine Journal},
keywords = {acute spinal cord injury,clinical guideline,spinal cord injury,traumatic spinal cord injury},
number = {3{\_}supplement},
pages = {84S--94S},
title = {{A Clinical Practice Guideline for the Management of Acute Spinal Cord Injury: Introduction, Rationale, and Scope}},
volume = {7},
year = {2017}
}
@article{Ocklenburg2013,
abstract = {Functional hemispheric asymmetries of speech production and perception are a key feature of the human language system, but their neurophysiological basis is still poorly understood. Using a combined fMRI and tract-based spatial statistics approach, we investigated the relation of microstructural asymmetries in language-relevant white matter pathways and functional activation asymmetries during silent verb generation and passive listening to spoken words. Tract-based spatial statistics revealed several leftward asymmetric clusters in the arcuate fasciculus and uncinate fasciculus that were differentially related to activation asymmetries in the two functional tasks. Frontal and temporal activation asymmetries during silent verb generation were positively related to the strength of specific microstructural white matter asymmetries in the arcuate fasciculus. In contrast, microstructural uncinate fasciculus asymmetries were related to temporal activation asymmetries during passive listening. These findings suggest that white matter asymmetries may indeed be one of the factors underlying functional hemispheric asymmetries. Moreover, they also show that specific localized white matter asymmetries might be of greater relevance for functional activation asymmetries than microstructural features of whole pathways. {\textcopyright} 2013 Elsevier Inc.},
author = {Ocklenburg, Sebastian and Hugdahl, Kenneth and Westerhausen, Ren{\'{e}}},
doi = {10.1016/j.neuroimage.2013.07.076},
file = {:Users/juandp77/Dropbox/references/NeuroImage/Structural white matter asymmetries in relation to functional asymmetries during speech perception and production - Ocklenburg, Hugdahl,.pdf:pdf},
isbn = {1053-8119},
issn = {10538119},
journal = {NeuroImage},
keywords = {Arcuate fasciculus,Diffusion tensor tractography,Functional hemispheric asymmetries,Structural hemispheric asymmetries,Tract-based spatial statistics,Uncinate fasciculus},
pages = {1088--1097},
pmid = {23921095},
publisher = {Elsevier Inc.},
title = {{Structural white matter asymmetries in relation to functional asymmetries during speech perception and production}},
url = {http://dx.doi.org/10.1016/j.neuroimage.2013.07.076},
volume = {83},
year = {2013}
}
@article{Recalde2008,
author = {Recalde, Rodolfo J and Paulo, S{\~{a}}o},
doi = {10.1227/01.NEU.0000297062.52433.3F},
file = {:Users/juandp77/Dropbox/references/Neurosurgery/M Icrosurgical a Natomy of the S Afe E Ntry Z Ones on the a Nterolateral B Rainstem R Elated To S Urgical a Pproaches To - Recalde, Paul.pdf:pdf},
isbn = {0000297062},
journal = {Neurosurgery},
keywords = {0000297062,01,10,1227,2008,3f,52433,brainstem,brainstem surgery,cavernous malformation,doi,neu,neurosurgery 62,ons17,ons9,safe entry zones,surgical anatomy,surgical approaches,white fiber dissection},
number = {March},
pages = {9--17},
title = {{M Icrosurgical a Natomy of the S Afe E Ntry Z Ones on the a Nterolateral B Rainstem R Elated To S Urgical a Pproaches To}},
volume = {62},
year = {2008}
}
@article{Ogilvy2001a,
author = {Ogilvy, C S and Stieg, P E and Awad, I and Brown, R D and Kondziolka, D and Rosenwasser, R and Young, W L and Hademenos, G},
doi = {10.1161/01.STR.32.6.1458},
file = {:Users/juandp77/Dropbox/references/Circulation/Recommendations for the management of intracranial arteriovenous malformations a statement for healthcare professionals from a special w.pdf:pdf},
isbn = {8006116083},
issn = {0039-2499},
journal = {Circulation},
number = {21},
pages = {2644--2657},
pmid = {11382737},
title = {{Recommendations for the management of intracranial arteriovenous malformations: a statement for healthcare professionals from a special writing group of the Stroke Council, American Stroke Association.}},
volume = {103},
year = {2001}
}
@article{Zdunczyk2017,
abstract = {BACKGROUND In degenerative cervical myelopathy (DCM), the dynamics of disease progression and the outcome after surgical decompression vary interindividually and do not necessarily correlate with radiological findings. OBJECTIVE To improve diagnostic power in DCM by better characterization of the underlying pathophysiology using navigated transcranial magnetic stimulation (nTMS). METHODS Eighteen patients with DCM due to cervical spinal canal stenosis were examined preoperatively with nTMS. On the basis of the initial Japanese Orthopedic Association (JOA) Score, 2 patient groups were established (JOA ≤12/{\textgreater}12). We determined the resting motor threshold, recruitment curve, cortical silent period, and motor area. Accordingly, 8 healthy subjects were examined. RESULTS Although the resting motor threshold was comparable in both groups (P = .578), the corticospinal excitability estimated by the recruitment curve was reduced in patients (P = .022). In patients with only mild symptoms (JOA {\textgreater} 12), a compensatory higher activation of non-primary motor areas was detected (P {\textless} .005). In contrast, patients with severe impairment (JOA ≤ 12) showed a higher cortical inhibition (P {\textless} .05) and reduced cortical motor area (P {\textless} .05) revealing a functional restriction on the cortical level. CONCLUSION Based on these results, we propose a new concept for functional compensation for DCM on the cortical and spinal level, ie corticospinal reserve capacity. nTMS is a useful tool to noninvasively characterize the pattern of functional impairment and compensatory reorganization in patients suffering from DCM. The change in nTMS parameters might serve as a valuable prognostic factor in these patients in the future.},
author = {Zdunczyk, Anna and Schwarzer, Vera and Mikhailov, Michael and Bagley, Brendon and Rosenstock, Tizian and Picht, Thomas and Vajkoczy, Peter},
doi = {10.1093/neuros/nyx437},
file = {:Users/juandp77/Dropbox/references/Clinical Neurosurgery/The corticospinal reserve capacity Reorganization of motor area and excitability as a novel pathophysiological concept in cervical myelo.pdf:pdf},
issn = {0148396X},
journal = {Clinical Neurosurgery},
keywords = {Cortical reorganization,Plasticity,Spinal cord injury,Spondylotic cervical myelopathy},
number = {4},
pages = {810--818},
pmid = {29165642},
title = {{The corticospinal reserve capacity: Reorganization of motor area and excitability as a novel pathophysiological concept in cervical myelopathy}},
url = {http://www.ncbi.nlm.nih.gov/pubmed/29165642{\%}0Ahttp://academic.oup.com/neurosurgery/advance-article/doi/10.1093/neuros/nyx437/4641662},
volume = {83},
year = {2018}
}
@article{Harvey2018,
abstract = {Patients with severe grades of life-threatening brain injury are commonly characterized as having devastating brain injury (DBI), which we have defined as: ‘any neurological condition that is assessed at the time of hospital admission as an immediate threat to life or incompatible with good functional recovery AND where early limitation or withdrawal of therapy is being considered'. The outcome in patients with DBI is often death or severe disability, and as a consequence rapid withdrawal of life sustaining therapies is commonly contemplated or undertaken. However, accurate prognostication in life-threatening brain injury is difficult, particularly at an early stage. Evidence from controlled studies to guide decision-making is limited, and there is a risk of a 'self-fulfilling prophecy', with early prognostication leading to early withdrawal of life sustaining therapies and death. The Joint Professional Standards committee of the Faculty of Intensive Care Medicine and the Intensive Care Society convened a consensus group with representation from stakeholder professional organizations to develop clear professional guidance in this area. It recognized that the weak evidence base makes GRADE guidelines difficult to justify. We have made 12 practical, pragmatic recommendations to help clinicians deliver safe, effective, equitable, and justifiable care within resource constrained healthcare systems. In the situation where patient-centred outcomes are recognized to be unacceptable, regardless of the extent of neurological improvement, then early transition to palliative care is appropriate. These recommendations are intended to apply where the primary pathology is DBI, rather than where DBI has compounded a progressive and irreversible deterioration in other life-threatening comorbidities.},
author = {Harvey, D. and Butler, J. and Groves, J. and Manara, A. and Menon, D. and Thomas, E. and Wilson, M.},
doi = {10.1016/j.bja.2017.10.002},
file = {:Users/juandp77/Dropbox/references/British Journal of Anaesthesia/Management of perceived devastating brain injury after hospital admission a consensus statement from stakeholder professional organizati.pdf:pdf},
issn = {14716771},
journal = {British Journal of Anaesthesia},
keywords = {brain injuries,clinical decision making,practise guideline},
number = {1},
pages = {138--145},
pmid = {29397121},
publisher = {Elsevier Ltd},
title = {{Management of perceived devastating brain injury after hospital admission: a consensus statement from stakeholder professional organizations}},
url = {https://doi.org/10.1016/j.bja.2017.10.002},
volume = {120},
year = {2018}
}
@article{Kulik2013,
abstract = {PURPOSE: Neurophysiological monitoring aims to improve the safety of pedicle screw placement, but few quantitative studies assess specificity and sensitivity. In this study, screw placement within the pedicle is measured (post-op CT scan, horizontal and vertical distance from the screw edge to the surface of the pedicle) and correlated with intraoperative neurophysiological stimulation thresholds.$\backslash$n$\backslash$nMETHODS: A single surgeon placed 68 thoracic and 136 lumbar screws in 30 consecutive patients during instrumented fusion under EMG control. The female to male ratio was 1.6 and the average age was 61.3 years (SD 17.7). Radiological measurements, blinded to stimulation threshold, were done on reformatted CT reconstructions using OsiriX software. A standard deviation of the screw position of 2.8 mm was determined from pilot measurements, and a 1 mm of screw-pedicle edge distance was considered as a difference of interest (standardised difference of 0.35) leading to a power of the study of 75 {\%} (significance level 0.05).$\backslash$n$\backslash$nRESULTS: Correct placement and stimulation thresholds above 10 mA were found in 71 {\%} of screws. Twenty-two percent of screws caused cortical breach, 80 {\%} of these had stimulation thresholds above 10 mA (sensitivity 20 {\%}, specificity 90 {\%}). True prediction of correct position of the screw was more frequent for lumbar than for thoracic screws.$\backslash$n$\backslash$nCONCLUSION: A screw stimulation threshold of {\textgreater}10 mA does not indicate correct pedicle screw placement. A hypothesised gradual decrease of screw stimulation thresholds was not observed as screw placement approaches the nerve root. Aside from a robust threshold of 2 mA indicating direct contact with nervous tissue, a secondary threshold appears to depend on patients' pathology and surgical conditions.},
author = {Kulik, Gerit and Pralong, Etienne and McManus, John and Debatisse, Damien and Schizas, Constantin},
doi = {10.1007/s00586-013-2754-0},
file = {:Users/juandp77/Dropbox/references/European Spine Journal/A CT-based study investigating the relationship between pedicle screw placement and stimulation threshold of compound muscle action pote.pdf:pdf},
issn = {09406719},
journal = {European Spine Journal},
keywords = {Compound muscle action potential,Computer tomography imaging,Neurophysiological monitoring,Pedicle screw,Spinal fusion,Study power},
number = {9},
pages = {2062--2068},
pmid = {23686531},
title = {{A CT-based study investigating the relationship between pedicle screw placement and stimulation threshold of compound muscle action potentials measured by intraoperative neurophysiological monitoring}},
volume = {22},
year = {2013}
}
@misc{Tian2009,
abstract = {Improved pedicle screw insertion accuracy has been reported with the assistance of computer tomography-based navigation. Studies also indicated that fluoroscopy-based navigation offers high accuracy and is comparable to CT-based assistance. However, different population characteristics and assessment methods resulted in inconsistent conclusions. We searched OVID, Springer, and MEDLINE databases to conduct a meta-analysis of the published literature specifically looking at accuracy of pedicle screw placement with different navigation methods. Subgroups and descriptive statistics were determined based on the subject type (in vivo or cadaveric), navigational method, and spinal level. A total number of 7,533 pedicle screws were summarised in our database with 6,721 screws accurately inserted into the pedicles (89.22{\%}). Overall, the median placement accuracy for the in vivo CT-based navigation subgroup (90.76{\%}) was higher than that with the use of two-dimensional (2D) fluoroscopy-based navigation (85.48{\%}). We concluded that CT-based navigation could provide a higher accuracy in the placement of pedicle screws for all subgroups presented. In the lumbar level, 2D fluoroscopy-based navigation was comparable with CT-based navigation. Discrepancy between the two navigation types increased in the thoracic level for the in vivo populations, where there was less potential in the use of 2D fluoroscopy-based navigation than CT-based navigation.},
author = {Tian, Nai Feng and Xu, Hua Z.},
booktitle = {International Orthopaedics},
doi = {10.1007/s00264-009-0792-3},
file = {:Users/juandp77/Dropbox/references/International Orthopaedics/Image-guided pedicle screw insertion accuracy A meta-analysis - Tian, Xu - 2009.pdf:pdf},
isbn = {0026400907923},
issn = {03412695},
number = {4},
pages = {895--903},
pmid = {19421752},
title = {{Image-guided pedicle screw insertion accuracy: A meta-analysis}},
volume = {33},
year = {2009}
}
@article{Bulsara2005,
author = {Bulsara, Ketan R and Johnson, Joel and Villavicencio, Alan T},
doi = {10.3171/foc.2005.18.4.6},
file = {:Users/juandp77/Dropbox/references/Neurosurgical focus/Improvements in brain tumor surgery the modern history of awake craniotomies. - Bulsara, Johnson, Villavicencio - 2005.pdf:pdf},
issn = {1092-0684},
journal = {Neurosurgical focus},
number = {4},
pages = {e5},
pmid = {15844868},
title = {{Improvements in brain tumor surgery: the modern history of awake craniotomies.}},
volume = {18},
year = {2005}
}
@book{Hemphill2015,