ro.json

{
  "graphs" : [ {
    "nodes" : [ {
      "id" : "http://purl.obolibrary.org/obo/RO_0002291",
      "meta" : {
        "definition" : {
          "val" : "x is ubiquitously expressed in y if and only if x is expressed in y, and the majority of cells in y express x",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Revisit this term after coordinating with SO/SOM. The domain of this relation should be a sequence, as an instance of a DNA molecule is only expressed in the cell of which it is a part."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "ubiquitously expressed in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002292",
      "meta" : {
        "definition" : {
          "val" : "Inverse of 'expressed in'",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "expresses"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002297",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "GOC:mtg_berkeley_2013"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "an annotation of gene X to anatomical structure formation with results_in_formation_of UBERON:0000007 (pituitary gland) means that at the beginning of the process a pituitary gland does not exist and at the end of the process a pituitary gland exists."
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
          "val" : "results_in_formation_of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "every \"endocardial cushion formation\" (GO:0003272) results_in_formation_of some \"endocardial cushion\" (UBERON:0002062)"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "results in formation of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002298",
      "meta" : {
        "definition" : {
          "val" : "The relationship that links an entity with the process that results in the formation and shaping of that entity over time from an immature to a mature state.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension" ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
          "val" : "results_in_morphogenesis_of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "tongue morphogenesis (GO:0043587) results in morphogenesis of tongue (UBERON:0001723)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "an annotation of gene X to cell morphogenesis with results_in_morphogenesis_of CL:0000540 (neuron) means that at the end of the process an input neuron has attained its shape."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "GOC:mtg_berkeley_2013"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "results in morphogenesis of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002299",
      "meta" : {
        "definition" : {
          "val" : "The relationship that links an entity with a process that results in the progression of the entity over time that is independent of changes in it's shape and results in an end point state of that entity.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
          "val" : "results_in_maturation_of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : " an annotation of gene X to cell maturation with results_in_maturation_of CL:0000057 (fibroblast) means that the fibroblast is mature at the end of the process"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "GOC:mtg_berkeley_2013"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "bone maturation (GO:0070977) results_in_maturation_of bone (UBERON:0001474)"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "results in maturation of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002293",
      "meta" : {
        "definition" : {
          "val" : "inverse of ubiquiotously expressed in",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "ubiquitously expresses"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002295",
      "meta" : {
        "definition" : {
          "val" : "p results in the developmental progression of s iff p is a developmental process and s is an anatomical structure and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss).",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://wiki.geneontology.org/index.php/Ontology_extensions"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "This property and its subproperties are being used primarily for the definition of GO developmental processes. The property hierarchy mirrors the core GO hierarchy. In future we may be able to make do with a more minimal set of properties, but due to the way GO is currently structured we require highly specific relations to avoid incorrect entailments. To avoid this, the corresponding genus terms in GO should be declared mutually disjoint."
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
          "val" : "results_in_developmental_progression_of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "results in developmental progression of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002296",
      "meta" : {
        "definition" : {
          "val" : "p 'results in development of' c if and only if p is a developmental process and p results in the state of c changing from its initial state as a primordium or anlage through its mature state and to its final state.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
          "val" : "results_in_development_of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "every flower development (GO:0009908) results in development of some flower (PO:0009046)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.geneontology.org/GO.doc.development.shtml"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "results in development of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/PATO_0000001",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "quality (PATO)"
        } ]
      },
      "type" : "CLASS",
      "lbl" : "quality"
    }, {
      "id" : "http://purl.obolibrary.org/obo/valid_for_gocam",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "pg"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/subsets/"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2020-09-22T11:05:45Z"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "valid_for_gocam"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002286",
      "meta" : {
        "definition" : {
          "val" : "Inverse of developmentally preceded by",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "developmentally succeeded by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002287",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "'hypopharyngeal eminence' SubClassOf 'part of precursor of' some tongue"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "part of developmental precursor of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002285",
      "meta" : {
        "definition" : {
          "val" : "x developmentally replaces y if and only if there is some developmental process that causes x to move or to cease to exist, and for the site that was occupied by x to become occupied by y, where y either comes into existence in this site or moves to this site from somewhere else",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "replaces"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "This relation is intended for cases such as when we have a bone element replacing its cartilage element precursor. Currently most AOs represent this using 'develops from'. We need to decide whether 'develops from' will be generic and encompass replacement, or whether we need a new name for a generic relation that encompasses replacement and development-via-cell-lineage"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "developmentally replaces"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000092",
      "meta" : {
        "definition" : {
          "val" : "inverse of has disposition",
          "xrefs" : [ ]
        },
        "comments" : [ "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ],
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ]
      },
      "type" : "PROPERTY",
      "lbl" : "disposition of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000091",
      "meta" : {
        "definition" : {
          "val" : "a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "has disposition"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002026",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds between two images, A and B, where:\nA depicts X;\nB depicts Y;\nX and Y are both of type T'\nC is a 2 layer image consiting of layers A and B;\nA and B are aligned in C according to a shared co-ordinate framework so that common features of X and Y are co-incident with each other.\nNote: A and B may be 2D or 3D.\nExamples include: the relationship between two channels collected simultaneously from a confocal microscope; the relationship between an image dpeicting X and a painted annotation layer that delineates regions of X; the relationship between the tracing of a neuron on an EM stack and the co-ordinate space of the stack; the relationship between two separately collected images that have been brought into register via some image registration software.",
          "xrefs" : [ "GOC:dos" ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "dos"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-12-07T12:58:06Z"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "in register with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002029",
      "meta" : {
        "definition" : {
          "val" : "Then percentage of organisms in a population that die during some specified age range (age-specific mortality rate), minus the percentage that die in during the same age range in a wild-type population.",
          "xrefs" : [ "PMID:24138933", "Wikipedia:Infant_mortality" ]
        },
        "comments" : [ "This could be used to record the increased infant morality rate in some population compared to wild-type.  For examples of usage see http://purl.obolibrary.org/obo/FBcv_0000351 and subclasses." ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "dos"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2018-05-22T16:43:28Z"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has increased age-specific mortality rate"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000081",
      "meta" : {
        "definition" : {
          "val" : "a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence",
          "xrefs" : [ ]
        },
        "comments" : [ "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this investigator role is a role of this person"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is role of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "role_of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "A role inheres in its bearer at all times for which the role exists, however the role need not be realized at all the times that the role exists."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "role of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000080",
      "meta" : {
        "definition" : {
          "val" : "a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence",
          "xrefs" : [ ]
        },
        "comments" : [ "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "quality_of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "A quality inheres in its bearer at all times for which the quality exists."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is quality of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this red color is a quality of this apple"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "quality of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0044456",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000412",
          "val" : "http://purl.obolibrary.org/obo/go.owl"
        } ]
      },
      "type" : "CLASS",
      "lbl" : "synapse part"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000085",
      "meta" : {
        "definition" : {
          "val" : "a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "A bearer can have many functions, and its functions can exist for different periods of time, but none of its functions can exist when the bearer does not exist. A function need not be realized at all the times that the function exists."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this enzyme has function this catalysis function (more colloquially: this enzyme has this catalysis function)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has_function"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has function"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002264",
      "meta" : {
        "definition" : {
          "val" : "c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
        "synonyms" : [ {
          "pred" : "hasRelatedSynonym",
          "val" : "affects",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://wiki.geneontology.org/index.php/Acts_upstream_of_or_within"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "A gene product that has some activity, where that activity may be a part of a pathway or upstream of the pathway."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "acts upstream of or within"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002022",
      "meta" : {
        "comments" : [ "Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding  regulates the kinase activity (P2) of protein B then P1 directly regulates P2." ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-09-17T13:52:24Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "dos"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "directly regulated by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002023",
      "meta" : {
        "definition" : {
          "val" : "Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding  negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.",
          "xrefs" : [ "GOC:dos" ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-09-17T13:52:38Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "dos"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "directly negatively regulated by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002024",
      "meta" : {
        "definition" : {
          "val" : "Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.",
          "xrefs" : [ "GOC:dos" ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-09-17T13:52:47Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "dos"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "directly positively regulated by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002025",
      "meta" : {
        "definition" : {
          "val" : "A 'has effector activity' B if A and B are GO molecular functions (GO_0003674),  A 'has component activity' B and B is the effector (output function) of B.  Each compound function has only one effector activity.",
          "xrefs" : [ "GOC:dos" ]
        },
        "comments" : [ "This relation is designed for constructing compound molecular functions, typically in combination with one or more regulatory component activity relations." ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "dos"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-09-22T14:14:36Z"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has effector activity"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002260",
      "meta" : {
        "definition" : {
          "val" : "c has-biological-role r iff c has-role r and r is a biological role (CHEBI:24432)",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "has biological role"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002261",
      "meta" : {
        "definition" : {
          "val" : "c has-application-role r iff c has-role r and r is an application role (CHEBI:33232)",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "has application role"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000087",
      "meta" : {
        "definition" : {
          "val" : "a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has_role"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this person has role this investigator role (more colloquially: this person has this role of investigator)"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has role"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002020",
      "meta" : {
        "definition" : {
          "val" : "Holds between p and c when p is a transport process or transporter activity and the outcome of this p is to move c from one location to another.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "dos"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-07-20T17:11:08Z"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "transports"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002262",
      "meta" : {
        "definition" : {
          "val" : "c has-chemical-role r iff c has-role r and r is a chemical role (CHEBI:51086)",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "has chemical role"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000086",
      "meta" : {
        "definition" : {
          "val" : "a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this apple has quality this red color"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has_quality"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "A bearer can have many qualities, and its qualities can exist for different periods of time, but none of its qualities can exist when the bearer does not exist."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has quality"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002021",
      "meta" : {
        "definition" : {
          "val" : "A relationship between a process and a barrier, where the process occurs in a region spanning the barrier. For cellular processes the barrier is typically a membrane. Examples include transport across a membrane and membrane depolarization.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "dos"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-07-20T17:19:37Z"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "occurs across"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002263",
      "meta" : {
        "definition" : {
          "val" : "c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "A faulty traffic light (material entity) whose malfunctioning (a process) is causally upstream of a traffic collision (a process): the traffic light acts upstream of the collision."
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://wiki.geneontology.org/index.php/Acts_upstream_of"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "acts upstream of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002019",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds between between a receptor and an chemical entity, typically a small molecule or peptide, that carries information between cells or compartments of a cell and which binds the receptor and regulates its effector function.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "dos"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-07-19T17:30:36Z"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has ligand"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000079",
      "meta" : {
        "definition" : {
          "val" : "a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence",
          "xrefs" : [ ]
        },
        "comments" : [ "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this catalysis function is a function of this enzyme"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "function_of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is function of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "A function inheres in its bearer at all times for which the function exists, however the function need not be realized at all the times that the function exists."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "function of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002015",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole.  More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B.",
          "xrefs" : [ ]
        },
        "comments" : [ "By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components.  So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'." ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-05-24T09:31:17Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "dos"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has positive regulatory component activity"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002257",
      "meta" : {
        "definition" : {
          "val" : "Inverse of developmentally induced by",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "developmentally induces"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002258",
      "meta" : {
        "definition" : {
          "val" : "Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p",
          "xrefs" : [ ]
        },
        "comments" : [ "This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "false"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "In general you should not use this relation to make assertions - use one of the more specific relations below this one"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "developmentally preceded by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002016",
      "meta" : {
        "comments" : [ "A has necessary component activity B if A and B are GO molecular functions  (GO_0003674), A has_component B and B is necessary for A.  For example,  ATPase coupled transporter activity has necessary component ATPase activity; transcript factor activity has necessary component DNA binding activity." ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-05-24T09:36:08Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "dos"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has necessary component activity"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002017",
      "meta" : {
        "comments" : [ "A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B." ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "dos"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-05-24T09:44:33Z"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has component activity"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002259",
      "type" : "PROPERTY",
      "lbl" : "defined by inverse"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002018",
      "meta" : {
        "definition" : {
          "val" : "w 'has process component' p if p and w are processes,  w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-05-24T09:49:21Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "dos"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has component process"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002490",
      "meta" : {
        "definition" : {
          "val" : "x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (α(x) >= α(y) & α(x) <= ω(y)) OR (ω(x) <= ω(y) & ω(x) >= α(y))",
          "xrefs" : [ ]
        },
        "comments" : [ "The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription." ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "existence overlaps"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002495",
      "meta" : {
        "definition" : {
          "val" : "x immediate transformation of y iff x immediately succeeds y temporally at a time boundary t, and all of the matter present in x at t is present in y at t, and all the matter in y at t is present in x at t",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/RO_0002575",
          "val" : "http://purl.obolibrary.org/obo/RO_0002494"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "immediate transformation of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002011",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds between a  process that regulates a transport process and the entity transported by that process.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "regulates transport of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002253",
      "meta" : {
        "definition" : {
          "val" : "inverse of connecting branch of",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ]
      },
      "type" : "PROPERTY",
      "lbl" : "has connecting branch"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002496",
      "meta" : {
        "definition" : {
          "val" : "x existence starts during or after y if and only if the time point at which x starts is after or equivalent to the time point at which y starts. Formally: x existence starts during or after y iff α (x) >= α (y).",
          "xrefs" : [ ]
        },
        "comments" : [ "The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription." ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "existence starts during or after"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002254",
      "meta" : {
        "definition" : {
          "val" : "x has developmental contribution from y iff x has some part z such that z develops from y",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong]"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has developmental contribution from"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002012",
      "meta" : {
        "definition" : {
          "val" : "A part of relation that applies only between occurents.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "occurent part of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002013",
      "meta" : {
        "definition" : {
          "val" : "A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-05-24T09:30:46Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "dos"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has regulatory component activity"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002255",
      "meta" : {
        "definition" : {
          "val" : "inverse of has developmental contribution from",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "developmentally contributes to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002497",
      "meta" : {
        "definition" : {
          "val" : "x existence ends during or before y if and only if the time point at which x ends is before or equivalent to the time point at which y ends.",
          "xrefs" : [ ]
        },
        "comments" : [ "The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription." ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "existence ends during or before"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002014",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole.  More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B.",
          "xrefs" : [ ]
        },
        "comments" : [ "By convention GO molecular functions are classified by their effector function.  Internal regulatory functions are treated as components.  For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'." ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "dos"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-05-24T09:31:01Z"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has negative regulatory component activity"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002256",
      "meta" : {
        "definition" : {
          "val" : "t1 induced_by t2 if there is a process of developmental induction (GO:0031128) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor anatomical structure type T to T', where T' develops_from T",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Melissa Haendel"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "GO:0001759"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20064205"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "induced by"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "We place this under 'developmentally preceded by'. This placement should be examined in the context of reciprocal inductions[cjm]"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : " Developmental Biology, Gilbert, 8th edition, figure 6.5(F)"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "developmentally induced by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002491",
      "meta" : {
        "definition" : {
          "val" : "x exists during y if and only if: 1) the time point at which x begins to exist is after or equal to the time point at which y begins and 2) the time point at which x ceases to exist is before or equal to the point at which y ends. Formally: x existence starts and ends during y iff α(x) >= α(y) & α(x) <= ω(y) & ω(x) <= ω(y) & ω(x) >= α(y)",
          "xrefs" : [ ]
        },
        "comments" : [ "The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription." ],
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "exists during",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "existence starts and ends during"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002492",
      "meta" : {
        "definition" : {
          "val" : "x existence ends during y if and only if the time point at which x ends is before or equivalent to the time point at which y ends and after or equivalent to the point at which y starts. Formally: x existence ends during y iff ω(x) <= ω(y) and ω(x) >= α(y).",
          "xrefs" : [ ]
        },
        "comments" : [ "The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription." ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "existence ends during"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002493",
      "meta" : {
        "definition" : {
          "val" : "x existence ends with y if and only if the time point at which x ends is equivalent to the time point at which y ends. Formally: x existence ends with y iff ω(x) = ω(y).",
          "xrefs" : [ ]
        },
        "comments" : [ "The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription." ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "existence ends with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002252",
      "meta" : {
        "definition" : {
          "val" : "b connecting-branch-of s iff b is connected to s, and there exists some tree-like structure t such that the mereological sum of b plus s is either the same as t or a branching-part-of t.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "connecting branch of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002010",
      "meta" : {
        "definition" : {
          "val" : "x 'regulates in other organism' y if and only if: (x is the realization of a function to exert an effect on the frequency, rate or extent of y) AND (the agents of x are produced by organism o1 and the agents of y are produced by organism o2).",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "regulates in other organism"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002494",
      "meta" : {
        "definition" : {
          "val" : "x transformation of y if x is the immediate transformation of y, or is linked to y through a chain of transformation relationships",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "transformation of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002008",
      "meta" : {
        "definition" : {
          "val" : "A relation that holds between two linear structures that are approximately parallel to each other for their entire length and where either the two structures are adjacent to each other or one is part of the other.",
          "xrefs" : [ ]
        },
        "comments" : [ "Example: if we define region of chromosome as any subdivision of a chromosome along its long axis, then we can define a region of chromosome that contains only gene x as 'chromosome region' that coincident_with some 'gene x', where the term gene X corresponds to a genomic sequence." ],
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Note from NCEAS meeting: consider changing primary label"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "coincident with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002009",
      "meta" : {
        "definition" : {
          "val" : "A relation that applies between a cell(c) and a gene(g) , where the process of 'transcription, DNA templated (GO_0006351)' is occuring in in cell c and that process has input gene g.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/dc/terms/description",
          "val" : "x 'cell expresses' y iff:\ncell(x)\nAND gene(y)\nAND exists some 'transcription, DNA templated (GO_0006351)'(t)\nAND t occurs_in x\nAND t has_input y"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "cell expresses"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002004",
      "meta" : {
        "definition" : {
          "val" : "The relationship that holds between a trachea or tracheole and an antomical structure that is contained in (and so provides an oxygen supply to).",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "tracheates"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002488",
      "meta" : {
        "definition" : {
          "val" : "x existence starts during y if and only if the time point at which x starts is after or equivalent to the time point at which y starts and before or equivalent to the time point at which y ends. Formally: x existence starts during y iff α(x) >= α(y) & α(x) <= ω(y).",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "existence starts during"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002246",
      "meta" : {
        "definition" : {
          "val" : "g is under-expressed in t iff g is expressed in t, and the expression level of g is decreased relative to some background.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "under-expressed in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002005",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/22402613"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "innervated_by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002489",
      "meta" : {
        "definition" : {
          "val" : "x starts ends with y if and only if the time point at which x starts is equivalent to the time point at which y starts. Formally: x existence starts with y iff α(x) = α(y).",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "existence starts with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002248",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds between a substance and a chemical entity, if the chemical entity is part of the substance, and the chemical entity forms the biologically active component of the substance.",
          "xrefs" : [ ]
        },
        "synonyms" : [ {
          "pred" : "hasRelatedSynonym",
          "val" : "has active pharmaceutical ingredient",
          "xrefs" : [ ]
        }, {
          "pred" : "hasExactSynonym",
          "val" : "has active substance",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "Any portion of roundup 'has active ingredient' some glyphosate"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has active ingredient"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002006",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/22402613"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has synaptic terminal of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002007",
      "meta" : {
        "definition" : {
          "val" : "X outer_layer_of Y iff:\n. X :continuant that bearer_of some PATO:laminar\n. X part_of Y\n. exists Z :surface\n. X has_boundary Z\n. Z boundary_of Y\n\nhas_boundary: http://purl.obolibrary.org/obo/RO_0002002\nboundary_of: http://purl.obolibrary.org/obo/RO_0002000",
          "xrefs" : [ ]
        },
        "comments" : [ "A relationship that applies between a continuant and its outer, bounding layer.  Examples include the relationship between a multicellular organism and its integument, between an animal cell and its plasma membrane, and between a membrane bound organelle and its outer/bounding membrane." ],
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "bounding layer of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002249",
      "meta" : {
        "definition" : {
          "val" : "inverse of has active ingredient",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ]
      },
      "type" : "PROPERTY",
      "lbl" : "active ingredient in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002000",
      "meta" : {
        "definition" : {
          "val" : "a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "the surface of my skin is a 2D boundary of my body"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is 2D boundary of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is boundary of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "boundary of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "2D_boundary_of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "2D boundary of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002242",
      "meta" : {
        "definition" : {
          "val" : "A broad relationship between an exposure event or process and a process by which the exposure stressor comes into contact with the exposure receptor",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "ExO:0000055"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has exposure route"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002484",
      "meta" : {
        "definition" : {
          "val" : "Connects an ontology entity (class, property, etc) to a URL from which curator guidance can be obtained. This assertion is inherited in the same manner as functional annotations (e.g. for GO, over SubClassOf and part_of)",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "curator guidance link"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002001",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "May be obsoleted, see https://github.com/oborel/obo-relations/issues/260"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "aligned with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002485",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "See notes for inverse relation"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "receives input from"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002243",
      "meta" : {
        "definition" : {
          "val" : "A broad relationship between an exposure event or process and the course takes from the source to the target.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ExO_0000004"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has exposure transport path"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002002",
      "meta" : {
        "definition" : {
          "val" : "a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has_2D_boundary"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "my body has 2D boundary the surface of my skin"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has boundary"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has 2D boundary"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002486",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "This is an exploratory relation. The label is taken from the FMA. It needs aligned with the neuron-specific relations such as has postsynaptic terminal in."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "sends output to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002244",
      "meta" : {
        "definition" : {
          "val" : "Any relationship between an exposure event or process and any other entity.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving exposure events or processes."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "related via exposure to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002487",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, typically connecting an anatomical entity to a biological process or developmental stage."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "relation between physical entity and a process or stage"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002003",
      "meta" : {
        "definition" : {
          "val" : "A relation that holds between two neurons that are electrically coupled via gap junctions.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/22402613"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "electrically_synapsed_to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002245",
      "meta" : {
        "definition" : {
          "val" : "g is over-expressed in t iff g is expressed in t, and the expression level of g is increased relative to some background.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "over-expressed in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002480",
      "meta" : {
        "definition" : {
          "val" : "An interaction relation between x and y in which x catalyzes a reaction in which one or more ubiquitin groups are added to y",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Axiomatization to GO to be added later"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "ubiquitinates"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002481",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is kinase activity"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002240",
      "meta" : {
        "definition" : {
          "val" : "A broad relationship between an exposure event or process and any entity (e.g., an organism, organism population, or an organism part) that interacts with an exposure stimulus during the exposure event.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "ExO:0000001"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has exposure receptor"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002482",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is ubiquitination"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002241",
      "meta" : {
        "definition" : {
          "val" : "A broad relationship between an exposure event or process and any agent, stimulus, activity, or event that causes stress or tension on an organism and interacts with an exposure receptor during an exposure event.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "ExO:0000000"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has exposure stressor"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002483",
      "type" : "PROPERTY",
      "lbl" : "inherited annotation property"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000059",
      "meta" : {
        "definition" : {
          "val" : "A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process)."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The quality (a specifically dependent continuant) concretizes the journal article (a generically dependent continuant), and both depend on that copy of the printed journal (an independent continuant)."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "concretizes"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000058",
      "meta" : {
        "definition" : {
          "val" : "A relationship between a generically dependent continuant and a specifically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The journal article (a generically dependent continuant) is concretized as the quality (a specifically dependent continuant), and both depend on that copy of the printed journal (an independent continuant)."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process)."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is concretized as"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000057",
      "meta" : {
        "definition" : {
          "val" : "a relation between a process and a continuant, in which the continuant is somehow involved in the process",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this process has participant this input material (or this output material)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this blood coagulation has participant this blood clot"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has_participant"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this investigation has participant this investigator"
        }, {
          "pred" : "http://purl.org/dc/elements/1.1/source",
          "val" : "http://www.obofoundry.org/ro/#OBO_REL:has_participant"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "has participant"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has participant"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002235",
      "meta" : {
        "definition" : {
          "val" : "A parasite-of relationship in which the host is a plant and the parasite that attaches to the host stem (PO:0009047)",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "stem parasite of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002477",
      "meta" : {
        "definition" : {
          "val" : "A child nucleus relationship in which the cells are part of a hermaphroditic organism",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "child nucleus of in hermaphrodite"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002478",
      "meta" : {
        "definition" : {
          "val" : "A child nucleus relationship in which the cells are part of a male organism",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "child nucleus of in male"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002236",
      "meta" : {
        "definition" : {
          "val" : "A parasite-of relationship in which the host is a plant and the parasite that attaches to the host root (PO:0009005)",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "root parasite of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002479",
      "meta" : {
        "definition" : {
          "val" : "p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has part that occurs in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002237",
      "meta" : {
        "definition" : {
          "val" : "A sub-relation of parasite-of in which the parasite is a plant, and the parasite is parasitic under natural conditions and is also photosynthetic to some degree. Hemiparasites may just obtain water and mineral nutrients from the host plant. Many obtain at least part of their organic nutrients from the host as well.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "hemiparasite of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002238",
      "meta" : {
        "definition" : {
          "val" : "X 'has component participant' Y means X 'has participant' Y and there is a cardinality constraint that specifies the numbers of Ys.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Bill Duncan"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "This object property is needed for axioms using has_participant with a cardinality contrainsts; e.g., has_particpant min 2 object. However, OWL does not permit cardinality constrains with object properties that have property chains (like has_particant) or are transitive (like has_part).\n\nIf you need an axiom that says 'has_participant min 2 object', you should instead say 'has_component_participant min 2 object'."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has component participant"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002231",
      "meta" : {
        "definition" : {
          "val" : "x 'has starts location' y if and only if there exists some process z such that x 'starts with' z and z 'occurs in' y",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "starts with process that occurs in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has start location"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002473",
      "meta" : {
        "definition" : {
          "val" : "x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "'otolith organ' SubClassOf 'composed primarily of' some 'calcium carbonate'"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/22293552"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "composed primarily of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000052",
      "meta" : {
        "definition" : {
          "val" : "a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence.",
          "xrefs" : [ ]
        },
        "comments" : [ "Note that this relation was previously called \"inheres in\", but was changed to be called \"characteristic of\" because BFO2 uses \"inheres in\" in a more restricted fashion. This relation differs from BFO2:inheres_in in two respects: (1) it does not impose a range constraint, and thus it allows qualities of processes, as well as of information entities, whereas BFO2 restricts inheres_in to only apply to independent continuants (2) it is declared functional, i.e. something can only be a characteristic of one thing." ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this red color is a characteristic of this apple"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this fragility is a characteristic of this vase"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "inheres_in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "inheres in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "characteristic of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002232",
      "meta" : {
        "definition" : {
          "val" : "x 'has end location' y if and only if there exists some process z such that x 'ends with' z and z 'occurs in' y",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "ends with process that occurs in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has end location"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002474",
      "meta" : {
        "definition" : {
          "val" : "An assertion that holds between an OWL Object Property and a dispositional interpretation that elucidates how OWL Class Axioms or OWL Individuals that use this property are to be interpreted in a dispositional context. For example,  A binds B may be interpreted as A have a mutual disposition that is realized by binding to the other one.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "dispositional interpretation"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002233",
      "meta" : {
        "definition" : {
          "val" : "p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "consumes"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has input"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002475",
      "meta" : {
        "definition" : {
          "val" : "A is has_no_connections_with B if there are no parts of A or B that have a connection with the other.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "shares no connection with"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000425",
          "val" : "Class: <http://www.w3.org/2002/07/owl#Nothing> EquivalentTo: (BFO_0000050 some ?X) and (RO_0002170 some (BFO_0000050 some ?Y))"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "'pectoral appendage skeleton' has no connections with 'pelvic appendage skeleton'"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has no connections with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002234",
      "meta" : {
        "definition" : {
          "val" : "p has output c iff c is a participant in p, c is present at the end of p, and c is not present at the beginning of p.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/ro/subsets#ro-eco", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "produces"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has output"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002476",
      "meta" : {
        "definition" : {
          "val" : "c is a child nucleus of d if and only if c and d are both nuclei and parts of cells c' and d', where c' is derived from d' by mitosis and the genetic material in c is a copy of the generic material in d",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "This relation is primarily used in the worm anatomy ontology for representing lineage at the level of nuclei. However, it is applicable to any organismal cell lineage."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "ABal nucleus child nucleus of ABa nucleus (in C elegans)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "child nucleus of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000056",
      "meta" : {
        "definition" : {
          "val" : "a relation between a continuant and a process, in which the continuant is somehow involved in the process",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this investigator participates in this investigation"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this input material (or this output material) participates in this process"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this blood clot participates in this blood coagulation"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "participates in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "participates_in"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "participates in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002470",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is subject of eating interaction with"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "eats"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002471",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "eaten by"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is target of eating interaction with"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is eaten by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002472",
      "meta" : {
        "definition" : {
          "val" : "A relationship between a piece of evidence a and some entity b, where b is  an information content entity, material entity or process, and \nthe a supports either the existence of b, or the truth value of b.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is evidence for"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0000053",
      "meta" : {
        "definition" : {
          "val" : "Inverse of characteristic_of",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this apple is bearer of this red color"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this vase is bearer of this fragility"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is bearer of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "bearer_of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "bearer of"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has characteristic"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002230",
      "meta" : {
        "definition" : {
          "val" : "x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "finished by"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "ends with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002228",
      "meta" : {
        "definition" : {
          "val" : "A sub-relations of parasite-of in which the parasite that can complete its life cycle independent of a host.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "facultative parasite of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002229",
      "meta" : {
        "definition" : {
          "val" : "inverse of ends with",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "ends"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002224",
      "meta" : {
        "definition" : {
          "val" : "x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "started by"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "Every insulin receptor signaling pathway starts with the binding of a ligand to the insulin receptor"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "starts with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002466",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is commensalism"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002225",
      "meta" : {
        "definition" : {
          "val" : "x develops from part of y if and only if there exists some z such that x develops from z and z is part of y",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "develops from part of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002467",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is mutualism"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002226",
      "meta" : {
        "definition" : {
          "val" : "x develops_in y if x is located in y whilst x is developing",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "Jonathan Bard, EHDAA2"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "EHDAA2"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "develops in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002468",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is parasitism"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002469",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "provides nutrients for"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002227",
      "meta" : {
        "definition" : {
          "val" : "A sub-relation of parasite-of in which the parasite that cannot complete its life cycle without a host.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "obligate parasite of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/CARO_0001000",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000412",
          "val" : "http://purl.obolibrary.org/obo/caro.owl"
        } ]
      },
      "type" : "CLASS",
      "lbl" : "multi-cell-part structure"
    }, {
      "id" : "http://purl.obolibrary.org/obo/CARO_0001001",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000412",
          "val" : "http://purl.obolibrary.org/obo/caro.owl"
        } ]
      },
      "type" : "CLASS",
      "lbl" : "neuron projection bundle"
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0030424",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000412",
          "val" : "http://purl.obolibrary.org/obo/go.owl"
        } ]
      },
      "type" : "CLASS",
      "lbl" : "axon"
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0030425",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000412",
          "val" : "http://purl.obolibrary.org/obo/go.owl"
        } ]
      },
      "type" : "CLASS",
      "lbl" : "dendrite"
    }, {
      "id" : "http://purl.obolibrary.org/obo/valid_for_go_ontology",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/subsets/"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "pg"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2020-09-22T11:04:12Z"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "valid_for_go_ontology"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002220",
      "meta" : {
        "definition" : {
          "val" : "x adjacent to y if and only if x and y share a boundary.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "The skin of the forelimb is adjacent to the skin of the torso if these are considered anatomical subdivisions with a defined border. Otherwise a relation such as continuous_with would be used."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "The plasma membrane of a cell is adjacent to the cytoplasm, and also to the cell lumen which the cytoplasm occupies."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "This relation acts as a join point with BSPO"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "A caterpillar walking on the surface of a leaf is adjacent_to the leaf, if one of the caterpillar appendages is touching the leaf. In contrast, a butterfly flying close to a flower is not considered adjacent, unless there are any touching parts."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "The epidermis layer of a vertebrate is adjacent to the dermis."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "adjacent to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002462",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Experimental: relation used for defining interaction relations; the meaning of s 'subject participant in' p is determined by the type of p, where p must be a directional interaction process. For example, in a predator-prey interaction process the subject is the predator. We can imagine a reciprocal prey-predatory process with subject and object reversed."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "subject participant in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0003310",
      "meta" : {
        "definition" : {
          "val" : "A relationship between a condition (a phenotype or disease) and an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) where some or all aspects of the condition are reduced or eliminated by the presence of the entity.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "condition ameliorated by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002221",
      "meta" : {
        "definition" : {
          "val" : "inverse of surrounded by",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "surrounds"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002463",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Experimental: relation used for defining interaction relations; the meaning of s 'target participant in' p is determined by the type of p, where p must be a directional interaction process. For example, in a predator-prey interaction process the target is the prey. We can imagine a reciprocal prey-predatory process with subject and object reversed."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "target participant in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002222",
      "meta" : {
        "comments" : [ "A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations." ],
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "https://en.wikipedia.org/wiki/Allen%27s_interval_algebra"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends."
        }, {
          "pred" : "http://purl.org/dc/terms/source",
          "val" : "https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit?pli=1"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "temporally related to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002464",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "This property or its subproperties is not to be used directly. These properties exist as helper properties that are used to support OWL reasoning."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "helper property (not for use in curation)"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002223",
      "meta" : {
        "definition" : {
          "val" : "inverse of starts with",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "Allen"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "starts"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002465",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is symbiosis"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0003311",
      "meta" : {
        "definition" : {
          "val" : "A relationship between a condition (a phenotype or disease) and an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) where some or all aspects of the condition are worsened by the presence of the entity.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "condition exacerbated by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002460",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has vector"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002461",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Experimental: relation used for defining interaction relations. An interaction relation holds when there is an interaction event with two partners. In a directional interaction, one partner is deemed the subject, the other the target"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "partner in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0003307",
      "meta" : {
        "definition" : {
          "val" : "A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the presence of the entity reduces or eliminates some or all aspects of the condition.",
          "xrefs" : [ ]
        },
        "comments" : [ "Genetic variations can span any level of granularity from a full genome or genotype to an individual gene  or sequence alteration.  These variations can be represented at the physical level (DNA/RNA macromolecules or their parts, as in the ChEBI ontology and Molecular Sequence Ontology) or at the abstract level (generically dependent continuant sequence features that are carried by these macromolecules, as in the Sequence Ontology and Genotype Ontology).  The causal relations in this hierarchy can be used in linking either physical or abstract genetic variations to phenotypes or diseases they cause or contribute to. \n\nEnvironmental exposures include those imposed by natural environments, experimentally applied conditions, or clinical interventions." ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is preventative for condition"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "ameliorates condition"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002217",
      "meta" : {
        "definition" : {
          "val" : "OBSOLETE x actively participates in y if and only if x participates in y and x realizes some active role",
          "xrefs" : [ ]
        },
        "comments" : [ "Obsoleted as the inverse property was obsoleted." ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "agent in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0100001",
          "val" : "http://purl.obolibrary.org/obo/RO_0002608"
        } ],
        "deprecated" : true
      },
      "type" : "PROPERTY",
      "lbl" : "obsolete actively participates in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002459",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "a is a vector for b if a carries and transmits an infectious pathogen b into another living organism"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "Anopheles is a vector for Plasmodium"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is vector for"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002218",
      "meta" : {
        "definition" : {
          "val" : "OBSOLETE x has participant y if and only if x realizes some active role that inheres in y",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has agent"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0100001",
          "val" : "http://purl.obolibrary.org/obo/RO_0002500"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ],
        "deprecated" : true
      },
      "type" : "PROPERTY",
      "lbl" : "obsolete has active participant"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0003306",
      "meta" : {
        "definition" : {
          "val" : "A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity influences the frequency of the condition in a population.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "contributes to penetrance of condition"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "contributes to frequency of condition"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0003309",
      "meta" : {
        "definition" : {
          "val" : "A relationship between an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) and a condition (a phenotype or disease), where the presence of the entity worsens some or all aspects of the condition.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "exacerbates condition"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002219",
      "meta" : {
        "definition" : {
          "val" : "x surrounded_by y if and only if (1) x is adjacent to y and for every region r that is adjacent to x, r overlaps y (2) the shared boundary between x and y occupies the majority of the outermost boundary of x",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "surrounded by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0003308",
      "meta" : {
        "definition" : {
          "val" : "A relationship between an entity and a condition (phenotype or disease) with which it exhibits a statistical dependence relationship.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "correlated with condition"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002213",
      "meta" : {
        "definition" : {
          "val" : "Process(P1) postively regulates process(P2) iff: P1 initiates P2, or P1 increases the the frequency of initiation of P2 or the magnitude or rate of output of P2.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0004049",
          "val" : "http://purl.obolibrary.org/obo/RO_0002211"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "positively regulates (process to process)"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "positively regulates"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0003303",
      "meta" : {
        "definition" : {
          "val" : "A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity has some causal role for the condition.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "causes condition"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002455",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is subject of pollination interaction with"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://eol.org/schema/terms/pollinates"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "This relation is intended to be used for biotic pollination - e.g. a bee pollinating a flowering plant. Some kinds of pollination may be semibiotic - e.g. wind can have the role of pollinator. We would use a separate relation for this."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "Bees pollinate Flowers"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "pollinates"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002456",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has polinator"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is target of pollination interaction with"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://eol.org/schema/terms/hasPollinator"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "pollinated by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0003302",
      "meta" : {
        "definition" : {
          "val" : "A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity has some causal or contributing role that influences the condition.",
          "xrefs" : [ ]
        },
        "comments" : [ "Genetic variations can span any level of granularity from a full genome or genotype to an individual gene  or sequence alteration.  These variations can be represented at the physical level (DNA/RNA macromolecules or their parts, as in the ChEBI ontology and Molecular Sequence Ontology) or at the abstract level (generically dependent continuant sequence features that are carried by these macromolecules, as in the Sequence Ontology and Genotype Ontology).  The causal relations in this hierarchy can be used in linking either physical or abstract genetic variations to phenotypes or diseases they cause or contribute to.\n\nEnvironmental exposures include those imposed by natural environments, experimentally applied conditions, or clinical interventions." ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Note that relationships of phenotypes to organisms/strains that bear them, or diseases they are manifest in, should continue to use RO:0002200 ! 'has phenotype' and RO:0002201 ! 'phenotype of'."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "The genetic variant 'NM_007294.3(BRCA1):c.110C>A (p.Thr37Lys)' casues or contributes to the disease  'familial breast-ovarian cancer'.\n\nAn environment of exposure to arsenic causes or contributes to the phenotype of patchy skin hyperpigmentation, and the disease 'skin cancer'."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "causes or contributes to condition"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002214",
      "meta" : {
        "definition" : {
          "val" : "x has prototype y if and only if x is an instance of C and y is a prototypical instance of C. For example, every instance of heart, both normal and abnormal is related by the has prototype relation to some instance of a \"canonical\" heart, which participates in blood circulation.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "This property can be used to make weaker forms of certain relations by chaining an additional property. For example, we may say: retina SubClassOf has_prototype some 'detection of light'. i.e. every retina is related to a prototypical retina instance which is detecting some light. Note that this is very similar to 'capable of', but this relation affords a wider flexibility. E.g. we can make a relation between continuants."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "'human p53 protein' SubClassOf some ('has prototype' some ('participates in' some 'DNA repair'))"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "heart SubClassOf 'has prototype' some ('participates in' some 'blood circulation')"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "TODO: add homeomorphy axiom"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Experimental. In future there may be a formalization in which this relation is treated as a shortcut to some modal logic axiom. We may decide to obsolete this and adopt a more specific evolutionary relationship (e.g. evolved from)"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has prototype"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002457",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Intended to be used when the target of the relation is not itself consumed, and does not have integral parts consumed, but provided nutrients in some other fashion."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "acquires nutrients from"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002215",
      "meta" : {
        "definition" : {
          "val" : "A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. ",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/21208450"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "osteoclast SubClassOf 'capable of' some 'bone resorption'"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has function realized in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "For compatibility with BFO, this relation has a shortcut definition in which the expression \"capable of some P\" expands to \"bearer_of (some realized_by only P)\"."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20123131"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "capable of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0003305",
      "meta" : {
        "definition" : {
          "val" : "A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity influences the severity with which a condition manifests in an individual.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "contributes to expressivity of condition"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "contributes to severity of condition"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0003304",
      "meta" : {
        "definition" : {
          "val" : "A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity has some contributing role that influences the condition.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "contributes to condition"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002458",
      "meta" : {
        "definition" : {
          "val" : "inverse of preys on",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco", "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://eol.org/schema/terms/HasPredator"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://polytraits.lifewatchgreece.eu/terms/PRED"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is target of predation interaction with"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has predator"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "preyed upon by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002216",
      "meta" : {
        "definition" : {
          "val" : "c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has function in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/reflexivity/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "capable of part of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/CARO_0001010",
      "type" : "CLASS",
      "lbl" : "organism or virus or viroid"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002451",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds between a disease and organism",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "all dengue disease transmitted by some mosquito"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Add domain and range constraints"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "transmitted by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002210",
      "meta" : {
        "definition" : {
          "val" : "inverse of directly develops from",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "developmental precursor of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "directly develops into"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002452",
      "meta" : {
        "definition" : {
          "val" : "A relation that holds between a disease or an organism and a phenotype",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has symptom"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002211",
      "meta" : {
        "definition" : {
          "val" : "process(P1) regulates process(P2) iff: P1 results in the initiation or termination of P2 OR affects the frequency of its initiation or termination OR affects the magnitude or rate of output of P2.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Regulation precludes parthood; the regulatory process may not be within the regulated process."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "GO"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "We use 'regulates' here to specifically imply control. However, many colloquial usages of the term correctly correspond to the weaker relation of 'causally upstream of or within' (aka influences). Consider relabeling to make things more explicit"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Hill"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000600",
          "val" : "false"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Tanya Berardini"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "regulates (processual)"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "regulates"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002453",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "The term host is usually used for the larger (macro) of the two members of a symbiosis (GO)"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "host of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0003301",
      "meta" : {
        "definition" : {
          "val" : "A relation between a biological, experimental, or computational artifact and an entity it is used to study, in virtue of its replicating or approximating features of the studied entity.",
          "xrefs" : [ ]
        },
        "comments" : [ "The primary use case for this relation was to link a biological model system such as a cell line or model organism to a disease it is used to investigate, in virtue of the model system exhibiting features similar to that of the disease of interest. But the relation is defined more broadly to support other use cases, such as linking genes in which alterations are made to create model systems to the condition the system is used to interrogate, or computational models to real-world phenomena they are defined to simulate." ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is used to study"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Matthew Brush"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has role in modeling"
    }, {
      "id" : "http://purl.obolibrary.org/obo/PATO_0000402",
      "type" : "CLASS",
      "lbl" : "branched"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002454",
      "meta" : {
        "definition" : {
          "val" : "X 'has host' y if and only if: x is an organism, y is an organism, and x can live on the surface of or within the body of y",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://eol.org/schema/terms/hasHost"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has host"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002212",
      "meta" : {
        "definition" : {
          "val" : "Process(P1) negatively regulates process(P2) iff: P1 terminates P2, or P1 descreases the the frequency of initiation of P2 or the magnitude or rate of output of P2.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "negatively regulates (process to process)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0004050",
          "val" : "http://purl.obolibrary.org/obo/RO_0002211"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "negatively regulates"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002450",
      "meta" : {
        "definition" : {
          "val" : "The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.",
          "xrefs" : [ ]
        },
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "molecularly increases activity of",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Vasundra Touré"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "directly activates"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "directly positively regulates activity of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002206",
      "meta" : {
        "definition" : {
          "val" : "x expressed in y if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and the transcription of x is part of the gene expression process (iii) x is a mature gene product such as a protein, and x was translated or otherwise processes from a transcript that was transcribed as part of this gene expression process",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "'neural crest cell'  SubClassOf expresses some 'Wnt1 gene'"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "expressed in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002448",
      "meta" : {
        "definition" : {
          "val" : "The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.\n\nA and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.",
          "xrefs" : [ ]
        },
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "molecularly controls",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Vasundra Touré"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "directly regulates activity of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002449",
      "meta" : {
        "definition" : {
          "val" : "The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.",
          "xrefs" : [ ]
        },
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "molecularly decreases activity of",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Vasundra Touré"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "directly inhibits"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "directly negatively regulates activity of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002207",
      "meta" : {
        "definition" : {
          "val" : "Candidate definition: x directly_develops from y if and only if there exists some developmental process (GO:0032502) p such that x and y both participate in p, and x is the output of p and y is the input of p, and a substantial portion of the matter of x comes from y, and the start of x is coincident with or after the end of y.",
          "xrefs" : [ ]
        },
        "comments" : [ "TODO - add child relations from DOS" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "has developmental precursor"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0002575",
          "val" : "http://purl.obolibrary.org/obo/RO_0002202"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "FBbt"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "directly develops from"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002208",
      "meta" : {
        "definition" : {
          "val" : "A parasite that kills or sterilizes its host",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "parasitoid of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002209",
      "meta" : {
        "definition" : {
          "val" : "inverse of parasitoid of",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ]
      },
      "type" : "PROPERTY",
      "lbl" : "has parasitoid"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002202",
      "meta" : {
        "definition" : {
          "val" : "x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y",
          "xrefs" : [ ]
        },
        "comments" : [ "This is the transitive form of the develops from relation" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Terry Meehan"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Melissa Haendel"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "develops from"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002444",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "direct parasite of",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "Pediculus humanus capitis parasite of human"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "parasitizes"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://eol.org/schema/terms/parasitizes"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "parasite of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002203",
      "meta" : {
        "definition" : {
          "val" : "inverse of develops from",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Terry Meehan"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "develops into"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002445",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "directly parasitized by",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has parasite"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://eol.org/schema/terms/hasParasite"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "parasitised by"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "parasitized by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002446",
      "meta" : {
        "definition" : {
          "val" : "A biotic interaction relationship in which one partner is an organism and the other partner is inorganic. For example, the relationship between a sponge and the substrate to which is it anchored.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "synonyms" : [ {
          "pred" : "hasRelatedSynonym",
          "val" : "semibiotically interacts with",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://dx.doi.org/10.1016/j.ecoinf.2014.08.005"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "Porifiera attaches to substrate"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "participates in a abiotic-biotic interaction with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002204",
      "meta" : {
        "definition" : {
          "val" : "definition \"x has gene product of y if and only if y is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of that process is either y or something that is ribosomally translated from x\"",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "We would like to be able to express the rule: if t transcribed from g, and t is a noncoding RNA and has an evolved function, then t has gene product g."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "gene product of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002205",
      "meta" : {
        "definition" : {
          "val" : "x has gene product y if and only if x is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of that process is either y or something that is ribosomally translated from y",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "every sonic hedgehog protein (PR:000014841) is the gene product of some sonic hedgehog gene"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "every HOTAIR lncRNA is the gene product of some HOXC gene"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has gene product"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002447",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Axiomatization to GO to be added later"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "phosphorylates"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000116",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000122"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "editor note"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000117",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000122"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "term editor"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000114",
      "type" : "PROPERTY",
      "lbl" : "has curation status"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000115",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000122"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "definition"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000112",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000122"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "example of usage"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000111",
      "type" : "PROPERTY",
      "lbl" : "editor preferred term"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000118",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "alternative term"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000119",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000122"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "definition source"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002440",
      "meta" : {
        "definition" : {
          "val" : "A biotic interaction in which the two organisms live together in more or less intimate association.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "We follow GO and PAMGO in using 'symbiosis' as the broad term encompassing mutualism through parasitism"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/19278549"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "symbiotically interacts with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002441",
      "meta" : {
        "definition" : {
          "val" : "An interaction relationship between two organisms living together in more or less intimate association in a relationship in which one benefits and the other is unaffected (GO).",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/19278549"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "commensually interacts with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002200",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds between a biological entity and a phenotype. Here a phenotype is construed broadly as any kind of quality of an organism part, a collection of these qualities, or a change in quality or qualities (e.g. abnormally increased temperature). The subject of this relationship can be an organism (where the organism has the phenotype, i.e. the qualities inhere in parts of this organism), a genomic entity such as a gene or genotype (if modifications of the gene or the genotype causes the phenotype), or a condition such as a disease (such that if the condition inheres in an organism, then the organism has the phenotype).",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has phenotype"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002442",
      "meta" : {
        "definition" : {
          "val" : "An interaction relationship between two organisms living together in more or less intimate association in a relationship in which both organisms benefit from each other (GO).",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/19278549"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "mutualistically interacts with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002443",
      "meta" : {
        "definition" : {
          "val" : "An interaction relationship between two organisms living together in more or less intimate association in a relationship in which association is disadvantageous or destructive to one of the organisms (GO).",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/19278549"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "This relation groups a pair of inverse relations, parasite of and parasitized by"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "interacts with via parasite-host interaction"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002201",
      "meta" : {
        "definition" : {
          "val" : "inverse of has phenotype",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco", "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "phenotype of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002437",
      "meta" : {
        "definition" : {
          "val" : "An interaction relationship in which at least one of the partners is an organism and the other is either an organism or an abiotic entity with which the organism interacts.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://eol.org/schema/terms/interactsWith"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://dx.doi.org/10.1016/j.ecoinf.2014.08.005"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "interacts with on organism level"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "biotically interacts with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002438",
      "meta" : {
        "definition" : {
          "val" : "An interaction relationship in which the partners are related via a feeding relationship.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://dx.doi.org/10.1016/j.ecoinf.2014.08.005"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "trophically interacts with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002439",
      "meta" : {
        "definition" : {
          "val" : "An interaction relationship involving a predation process, where the subject kills the target in order to eat it or to feed to siblings, offspring or group members",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "Baleen whale preys on krill"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://eol.org/schema/terms/preysUpon"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "preys upon"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is subject of predation interaction with"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Jorrit Poelen"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "A wasp killing a Monarch larva in order to feed to offspring [http://www.inaturalist.org/observations/2942824]"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://www.inaturalist.org/observations/2942824"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Katja Shulz"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "preys on"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002433",
      "meta" : {
        "definition" : {
          "val" : "p contributes to morphology of w if and only if a change in the morphology of p entails a change in the morphology of w. Examples: every skull contributes to morphology of the head which it is a part of. Counter-example: nuclei do not generally contribute to the morphology of the cell they are part of, as they are buffered by cytoplasm.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "contributes to morphology of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002434",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds between two entities in which the processes executed by the two entities are causally connected.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "in pairwise interaction with",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://www.w3.org/2004/02/skos/core#closeMatch",
          "val" : "http://purl.obolibrary.org/obo/MI_0914"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/interaction-relations/"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Considering relabeling as 'pairwise interacts with'"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "interacts with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002435",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2004/02/skos/core#closeMatch",
          "val" : "http://purl.obolibrary.org/obo/MI_0208"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "An interaction that holds between two genetic entities (genes, alleles) through some genetic interaction (e.g. epistasis)"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ECO_0000316"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "genetically interacts with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002436",
      "meta" : {
        "definition" : {
          "val" : "An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "molecularly binds with"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "binds"
        }, {
          "pred" : "http://www.w3.org/2004/02/skos/core#closeMatch",
          "val" : "http://purl.obolibrary.org/obo/MI_0915"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ECO_0000353"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "molecularly interacts with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000125",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "INDIVIDUAL",
      "lbl" : "pending final vetting"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000122",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "INDIVIDUAL",
      "lbl" : "ready for release"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002430",
      "meta" : {
        "definition" : {
          "val" : "c involved in regulation of p if c is involved in some p' and p' negatively regulates some p",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0004050",
          "val" : "http://purl.obolibrary.org/obo/RO_0002428"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "involved in negative regulation of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002431",
      "meta" : {
        "definition" : {
          "val" : "c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "involved in or reguates"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "OWL does not allow defining object properties via a Union"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "involved in or involved in regulation of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002432",
      "meta" : {
        "definition" : {
          "val" : "c executes activity in d if and only if c enables p and p occurs_in d.  Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure.",
          "xrefs" : [ "GOC:cjm", "GOC:dos" ]
        },
        "comments" : [ "" ],
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "enables activity in",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "executes activity in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "A protein that enables activity in a cytosol."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is active in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002426",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "differs in attribute"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002427",
      "meta" : {
        "definition" : {
          "val" : "inverse of causally upstream of or within",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "causally downstream of or within"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002428",
      "meta" : {
        "definition" : {
          "val" : "c involved in regulation of p if c is involved in some p' and p' regulates some p",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "involved in regulation of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0008150",
      "type" : "CLASS",
      "lbl" : "biological_process"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002429",
      "meta" : {
        "definition" : {
          "val" : "c involved in regulation of p if c is involved in some p' and p' positively regulates some p",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/RO_0004049",
          "val" : "http://purl.obolibrary.org/obo/RO_0002428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "involved in positive regulation of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002422",
      "meta" : {
        "definition" : {
          "val" : "Used to annotate object properties to describe a logical meta-property or characteristic of the object property.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "logical macro assertion on an object property"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002423",
      "type" : "PROPERTY",
      "lbl" : "logical macro assertion on an annotation property"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002424",
      "meta" : {
        "comments" : [ "This is an exploratory relation" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "false"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://code.google.com/p/phenotype-ontologies/w/edit/PhenotypeModelCompetencyQuestions"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "differs in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002425",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "differs in attribute of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002420",
      "meta" : {
        "definition" : {
          "val" : "A logical macro assertion whose domain is an IRI for a class",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "The domain for this class can be considered to be owl:Class, but we cannot assert this in OWL2-DL"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "logical macro assertion on a class"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002421",
      "meta" : {
        "definition" : {
          "val" : "A logical macro assertion whose domain is an IRI for a property",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "logical macro assertion on a property"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002416",
      "meta" : {
        "definition" : {
          "val" : "An assertion that involves at least one OWL object that is intended to be expanded into one or more logical axioms. The logical expansion can yield axioms expressed using any formal logical system, including, but not limited to OWL2-DL.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/shortcut-relations/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "logical macro assertion"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002418",
      "meta" : {
        "definition" : {
          "val" : "p 'causally upstream or within' q iff (1) the end of p is before the end of q and (2) the execution of p exerts some causal influence over the outputs of q; i.e. if p was abolished or the outputs of p were to be modified, this would necessarily affect q.",
          "xrefs" : [ ]
        },
        "synonyms" : [ {
          "pred" : "hasRelatedSynonym",
          "val" : "affects",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "influences (processual)"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "causally upstream of or within"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002411",
      "meta" : {
        "definition" : {
          "val" : "p is causally upstream of q if and only if p precedes q and p and q are linked in a causal chain",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "causally upstream of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002412",
      "meta" : {
        "definition" : {
          "val" : "p is immediately causally upstream of q iff both (a) p immediately precedes q and (b) p is causally upstream of q. In addition, the output of p  must be an input of q.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0002575",
          "val" : "http://purl.obolibrary.org/obo/RO_0002411"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "immediately causally upstream of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002413",
      "meta" : {
        "definition" : {
          "val" : "p1 directly provides input for p2 iff there exists some c such that p1 has_output c and p2 has_input c",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "directly provides input for (process to process)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "This is currently called 'directly provides input for' to be consistent with our terminology where we use 'direct' whenever two occurrents succeed one another directly. We may relabel this simply 'provides input for', as directness is implicit"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "directly provides input for"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002414",
      "meta" : {
        "definition" : {
          "val" : "transitive form of directly_provides_input_for",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "This is a grouping relation that should probably not be used in annotation. Consider instead the child relation 'directly provides input for' (which may later be relabeled simply to 'provides input for')"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "transitively provides input for (process to process)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "transitively provides input for"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002419",
      "meta" : {
        "definition" : {
          "val" : "An assertion that holds between an OWL Annotation Property P and a non-negative integer N, with the interpretation: for any P(i j) it must be the case that | { k : P(i k) } | = N.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "annotation property cardinality"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002410",
      "meta" : {
        "definition" : {
          "val" : "This relation groups causal relations between material entities and causal relations between processes",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents.\n\nTo define causal relations in an activity-flow type network, we make use of 3 primitives:\n\n * Temporal: how do the intervals of the two occurrents relate? \n * Is the causal relation regulatory?\n * Is the influence positive or negative\n\nThe first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified.\n\nFor the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule.\n\nFor the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral.\n\nEach of these 3 primitives can be composed to yield a cross-product of different relation types."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "causally related to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002404",
      "meta" : {
        "definition" : {
          "val" : "inverse of upstream of",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "causally downstream of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002405",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "immediately causally downstream of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002406",
      "meta" : {
        "definition" : {
          "val" : "p directly activates q if and only if p is immediately upstream of q and p is the realization of a function to increase the rate or activity of q",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "directly activates (process to process)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "directly positively regulates"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "directly activates"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002407",
      "meta" : {
        "definition" : {
          "val" : "p indirectly activates q if and only if p is upstream of q and there is a chain of directly activates relationships connecting p and q, where the chain is of length greater than one.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0002579",
          "val" : "http://purl.obolibrary.org/obo/RO_0002213"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "indirectly positively regulates"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "indirectly activates"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002400",
      "meta" : {
        "definition" : {
          "val" : "p has direct input c iff c is a participant in p, c is present at the start of p, and the state of c is modified during p.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "'protein catabolic process' SubClassOf has_direct_input some protein"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "This is likely to be obsoleted. A candidate replacement would be a new relation 'has bound input' or 'has substrate'"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "directly consumes"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has direct input"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002401",
      "meta" : {
        "comments" : [ "Likely to be obsoleted. See:\nhttps://docs.google.com/document/d/1QMhs9J-P_q3o_rDh-IX4ZEnz0PnXrzLRVkI3vvz8NEQ/edit" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ],
        "deprecated" : true
      },
      "type" : "PROPERTY",
      "lbl" : "obsolete has indirect input"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002402",
      "meta" : {
        "definition" : {
          "val" : "p has direct input c iff c is a participanti n p, c is present at the end of p, and c is not present at the beginning of c. ",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "directly produces"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "translation SubClassOf has_direct_output some protein"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        } ],
        "deprecated" : true
      },
      "type" : "PROPERTY",
      "lbl" : "obsolete has direct output"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002403",
      "meta" : {
        "comments" : [ "Likely to be obsoleted. See:\nhttps://docs.google.com/document/d/1QMhs9J-P_q3o_rDh-IX4ZEnz0PnXrzLRVkI3vvz8NEQ/edit" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        } ],
        "deprecated" : true
      },
      "type" : "PROPERTY",
      "lbl" : "obsolete has indirect output"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002408",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "directly inhibits (process to process)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "directly negatively regulates"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "directly inhibits"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002409",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0002579",
          "val" : "http://purl.obolibrary.org/obo/RO_0002212"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "indirectly negatively regulates"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "indirectly inhibits"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002640",
      "meta" : {
        "definition" : {
          "val" : "A sub-relation of endoparasite-of in which the parasite inhabits host cells.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "https://en.wikipedia.org/wiki/Parasitism#Types"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "intracellular endoparasite of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002641",
      "meta" : {
        "definition" : {
          "val" : "inverse of intracellular endoparasite of",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ]
      },
      "type" : "PROPERTY",
      "lbl" : "has intracellular endoparasite"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002635",
      "type" : "PROPERTY",
      "lbl" : "has endoparasite"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002636",
      "meta" : {
        "definition" : {
          "val" : "A sub-relation of parasite-of in which the parasite is partially an endoparasite and partially an ectoparasite",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "mesoparasite of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002637",
      "meta" : {
        "definition" : {
          "val" : "inverse of mesoparasite of",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ]
      },
      "type" : "PROPERTY",
      "lbl" : "has mesoparasite"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002638",
      "meta" : {
        "definition" : {
          "val" : "A sub-relation of endoparasite-of in which the parasite inhabits the spaces between host cells.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "https://en.wikipedia.org/wiki/Parasitism#Types"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "intercellular endoparasite of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002632",
      "meta" : {
        "definition" : {
          "val" : "A sub-relation of parasite-of in which the parasite lives on or in the integumental system of the host",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "https://en.wikipedia.org/wiki/Parasitism#Types"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "ectoparasite of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002633",
      "meta" : {
        "definition" : {
          "val" : "inverse of ectoparasite of",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ]
      },
      "type" : "PROPERTY",
      "lbl" : "has ectoparasite"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002634",
      "meta" : {
        "synonyms" : [ {
          "pred" : "hasRelatedSynonym",
          "val" : "lives inside of",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "https://en.wikipedia.org/wiki/Parasitism#Types"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "A sub-relation of parasite-of in which the parasite lives inside the host, beneath the integumental system"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "endoparasite of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002639",
      "meta" : {
        "definition" : {
          "val" : "inverse of intercellular endoparasite of",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ]
      },
      "type" : "PROPERTY",
      "lbl" : "has intercellular endoparasite"
    }, {
      "id" : "http://www.geneontology.org/formats/oboInOwl#hasDbXref",
      "type" : "PROPERTY",
      "lbl" : "database_cross_reference"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002630",
      "meta" : {
        "definition" : {
          "val" : "Process(P1) directly negatively regulates process(P2) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding  negatively regulates the kinase activity (P2) of protein B then P1 directly negatively regulates P2.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "directly negatively regulates (process to process)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0004050",
          "val" : "http://purl.obolibrary.org/obo/RO_0002578"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "directly negatively regulates"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002624",
      "type" : "PROPERTY",
      "lbl" : "lays eggs in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002625",
      "type" : "PROPERTY",
      "lbl" : "has eggs laid in by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002626",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "https://github.com/jhpoelen/eol-globi-data/issues/143"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "kills"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002627",
      "type" : "PROPERTY",
      "lbl" : "is killed by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002622",
      "type" : "PROPERTY",
      "lbl" : "visits flowers of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002623",
      "type" : "PROPERTY",
      "lbl" : "has flowers visited by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/valid_for_go_gp2term",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "pg"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2020-09-22T11:05:18Z"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/subsets/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "valid_for_go_gp2term"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002629",
      "meta" : {
        "definition" : {
          "val" : "Process(P1) directly postively regulates process(P2) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P1 directly positively regulates P2.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "directly positively regulates (process to process)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0004049",
          "val" : "http://purl.obolibrary.org/obo/RO_0002578"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "directly positively regulates"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002613",
      "meta" : {
        "definition" : {
          "val" : "A relationship between a sentence and an instance of a piece of evidence in which the evidence contradicts the axiom",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "This annotation property is intended to be used in an OWL Axiom Annotation to connect an OWL Axiom to an instance of an ECO (evidence type ontology class). Because in OWL, all axiom annotations must use an Annotation Property, the value of the annotation cannot be an OWL individual, the convention is to use an IRI of the individual."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "axiom contradicted by evidence"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002614",
      "meta" : {
        "definition" : {
          "val" : "A relationship between a piece of evidence and an entity that plays a role in supporting that evidence.",
          "xrefs" : [ ]
        },
        "comments" : [ "In the Gene Ontology association model, this corresponds to the With/From field" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "An instance of a sequence similarity evidence (ECO:0000044) that uses a homologous sequence UniProtKB:P12345 as support."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is evidence with support from"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002615",
      "meta" : {
        "definition" : {
          "val" : "Inverse of is-model-of",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "has model"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002616",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is a grouping relation."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "related via evidence or inference to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002610",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds between two entities, where the entities exhibit a statistical dependence relationship. The entities may be statistical variables, or they may be other kinds of entities such as diseases, chemical entities or processes.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Groups both positive and negative correlation"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "correlated with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002611",
      "type" : "PROPERTY",
      "lbl" : "evidential logical macro assertion on an axiom"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002612",
      "meta" : {
        "definition" : {
          "val" : "A relationship between a sentence and an instance of a piece of evidence in which the evidence supports the axiom",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "This annotation property is intended to be used in an OWL Axiom Annotation to connect an OWL Axiom to an instance of an ECO (evidence type ontology class). Because in OWL, all axiom annotations must use an Annotation Property, the value of the annotation cannot be an OWL individual, the convention is to use an IRI of the individual."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "axiom has evidence"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000589",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "OBO foundry unique label"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002617",
      "meta" : {
        "definition" : {
          "val" : "this property relates an IRI to the xsd boolean value \"True\" if the IRI is intended to be the representative IRI for a collection of classes that are mutually equivalent.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "In the context of a particular project, the IRI with CURIE NCBIGene:64327 (which in this example denotes a class) is considered to be representative. This means that if we have equivalent classes with IRIs OMIM:605522, ENSEMBL:ENSG00000105983, HGNC:13243 forming an equivalence set, the NCBIGene is considered the representative member IRI. Depending on the policies of the project, the classes may be merged, or the NCBIGene IRI may be chosen as the default in a user interface context."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "If it is necessary to make the context explicit, an axiom annotation can be added to the annotation assertion"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "OWLAPI Reasoner documentation for representativeElement, which follows a similar idea, but selects an arbitrary member"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is representative IRI for equivalence set"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002618",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://github.com/oborel/obo-relations/issues/74"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "visits"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002619",
      "type" : "PROPERTY",
      "lbl" : "visited by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0003674",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "molecular process"
        } ]
      },
      "type" : "CLASS",
      "lbl" : "molecular_function"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_HOM0000028",
      "meta" : {
        "definition" : {
          "val" : "Biological homology that is characterized by changes, over evolutionary time, in the rate or timing of developmental events of homologous structures.",
          "xrefs" : [ "http://purl.obolibrary.org/obo/HOM_0000028", "ISBN:978-0674639416" ]
        },
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "heterochrony",
          "xrefs" : [ ]
        }, {
          "pred" : "hasExactSynonym",
          "val" : "heterochronous homologous to",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/dc/elements/1.1/source",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20116127"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/HOM_0000028"
        }, {
          "pred" : "http://purl.org/dc/elements/1.1/creator",
          "val" : "http://bgee.unil.ch"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "in heterochronous homology relationship with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_HOM0000029",
      "meta" : {
        "definition" : {
          "val" : "Heterochronous homology that is produced by a retention in adults of a species of traits previously seen only in juveniles.",
          "xrefs" : [ "http://en.wikipedia.org/wiki/Pedomorphosis", "http://purl.obolibrary.org/obo/HOM_0000029", "ISBN:978-0674639416" ]
        },
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "juvenification",
          "xrefs" : [ ]
        }, {
          "pred" : "hasExactSynonym",
          "val" : "pedomorphosis",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/HOM_0000029"
        }, {
          "pred" : "http://purl.org/dc/elements/1.1/source",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20116127"
        }, {
          "pred" : "http://purl.org/dc/elements/1.1/creator",
          "val" : "http://bgee.unil.ch"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "in paedomorphorsis relationship with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_HOM0000026",
      "meta" : {
        "definition" : {
          "val" : "1:many orthology that involves a gene in species A and its ortholog in species B, when duplications more recent than the species split have occurred in species A but not in species B.",
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        } ],
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          "pred" : "http://purl.org/dc/elements/1.1/creator",
          "val" : "http://bgee.unil.ch"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
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      },
      "type" : "PROPERTY",
      "lbl" : "in homoplasy relationship with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_HOM0000003",
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        "definition" : {
          "val" : "Similarity that is characterized by the organization of anatomical structures through the expression of homologous or identical patterning genes.",
          "xrefs" : [ "http://dx.doi.org/10.1007/BF02814484", "http://dx.doi.org/10.1007/s00427-003-0301-4", "http://dx.doi.org/10.1186/1742-9994-2-15", "http://purl.obolibrary.org/obo/HOM_0000003" ]
        },
        "comments" : [ "Homology and homocracy are not mutually exclusive. The homology relationships of patterning genes may be unresolved and thus may include orthologues and paralogues." ],
        "xrefs" : [ {
          "val" : "ECO:0000075"
        } ],
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "homocracous to",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/dc/elements/1.1/creator",
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        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/HOM_0000003"
        }, {
          "pred" : "http://purl.org/dc/elements/1.1/source",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20116127"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "in homocracy relationship with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_HOM0000000",
      "meta" : {
        "definition" : {
          "val" : "Relation between biological objects that resemble or are related to each other sufficiently to warrant a comparison.",
          "xrefs" : [ "http://purl.obolibrary.org/obo/HOM_0000000", "BGEE:curator" ]
        },
        "xrefs" : [ {
          "val" : "ECO:0000041"
        }, {
          "val" : "SO:similar_to"
        } ],
        "synonyms" : [ {
          "pred" : "hasRelatedSynonym",
          "val" : "resemblance",
          "xrefs" : [ ]
        }, {
          "pred" : "hasExactSynonym",
          "val" : "sameness",
          "xrefs" : [ ]
        }, {
          "pred" : "hasExactSynonym",
          "val" : "similar to",
          "xrefs" : [ ]
        }, {
          "pred" : "hasRelatedSynonym",
          "val" : "correspondence",
          "xrefs" : [ "http://dx.doi.org/10.1007/BF02814479" ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
          "val" : "http://purl.obolibrary.org/obo/BFO_0000003"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
          "val" : "http://purl.obolibrary.org/obo/BFO_0000002"
        }, {
          "pred" : "http://purl.org/dc/elements/1.1/creator",
          "val" : "http://bgee.unil.ch"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "TODO: Add homeomorphy axiom"
        }, {
          "pred" : "http://purl.org/dc/elements/1.1/source",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20116127"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/HOM_0000000"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "in similarity relationship with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_HOM0000001",
      "meta" : {
        "definition" : {
          "val" : "Similarity that results from common evolutionary origin.",
          "xrefs" : [ "http://dx.doi.org/10.1002/bies.950180611", "http://dx.doi.org/10.1002/jmor.1051730307", "http://dx.doi.org/10.1007/BF02814480", "http://purl.obolibrary.org/obo/HOM_0000001" ]
        },
        "comments" : [ "This broad definition encompasses all the working definitions proposed so far in the literature." ],
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "homologous to",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/HOM_0000001"
        }, {
          "pred" : "http://purl.org/dc/elements/1.1/source",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20116127"
        }, {
          "pred" : "http://purl.org/dc/elements/1.1/creator",
          "val" : "http://bgee.unil.ch"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "in homology relationship with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_HOM0000075",
      "meta" : {
        "definition" : {
          "val" : "Historical homology that involves orthologous pairs of transcription factors and downstream regulated genes in different organisms.",
          "xrefs" : [ "http://dx.doi.org/10.1101/gr.1774904", "http://purl.obolibrary.org/obo/HOM_0000075" ]
        },
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "regulogous to",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/dc/elements/1.1/source",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20116127"
        }, {
          "pred" : "http://purl.org/dc/elements/1.1/creator",
          "val" : "http://bgee.unil.ch"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/HOM_0000075"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "in regulogy relationship with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_HOM0000073",
      "meta" : {
        "definition" : {
          "val" : "Synology that results from allopolyploidy.",
          "xrefs" : [ "http://dx.doi.org/10.1073/pnas.0505156102", "http://purl.obolibrary.org/obo/HOM_0000073" ]
        },
        "comments" : [ "On a long term, it is hard to distinguish allopolyploidy from whole genome duplication." ],
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "homoeologous to",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/dc/elements/1.1/creator",
          "val" : "http://bgee.unil.ch"
        }, {
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          "val" : "http://purl.obolibrary.org/obo/HOM_0000073"
        }, {
          "pred" : "http://purl.org/dc/elements/1.1/source",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20116127"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "in homoeology relationship with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_HOM0000074",
      "meta" : {
        "definition" : {
          "val" : "Iterative homology that involves two structures, one of which originated as a duplicate of the other and co-opted the expression of patterning genes of the ancestral structure.",
          "xrefs" : [ "http://dx.doi.org/10.1007/s10441-007-9023-8", "http://dx.doi.org/10.1046/j.1525-142x.2000.00054.x", "http://purl.obolibrary.org/obo/HOM_0000074" ]
        },
        "synonyms" : [ {
          "pred" : "hasRelatedSynonym",
          "val" : "axis paramorphism",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/HOM_0000074"
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          "pred" : "http://purl.org/dc/elements/1.1/source",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20116127"
        }, {
          "pred" : "http://purl.org/dc/elements/1.1/creator",
          "val" : "http://bgee.unil.ch"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "in paramorphism relationship with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_HOM0000071",
      "meta" : {
        "definition" : {
          "val" : "Structural homology that involves structures with the same or similar relative positions.",
          "xrefs" : [ "http://dx.doi.org/10.1007/BF02814484", "http://dx.doi.org/10.1007/BF02814485", "http://purl.obolibrary.org/obo/HOM_0000071", "ISBN:0123195837" ]
        },
        "comments" : [ "Theissen (2005) mentions that some authors may consider homotopy to be distinct from homology, but this is not the standard use." ],
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "homotopous to",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/dc/elements/1.1/creator",
          "val" : "http://bgee.unil.ch"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/HOM_0000071"
        }, {
          "pred" : "http://purl.org/dc/elements/1.1/source",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20116127"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "in homotopy relationship with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_HOM0000072",
      "meta" : {
        "definition" : {
          "val" : "Biological homology that involves an ectopic structure and the normally positioned structure.",
          "xrefs" : [ "http://dx.doi.org/10.1007/BF02814485", "http://dx.doi.org/10.1016/j.cell.2008.06.030", "http://purl.obolibrary.org/obo/HOM_0000072" ]
        },
        "synonyms" : [ {
          "pred" : "hasRelatedSynonym",
          "val" : "heterotopy",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/dc/elements/1.1/source",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20116127"
        }, {
          "pred" : "http://purl.org/dc/elements/1.1/creator",
          "val" : "http://bgee.unil.ch"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/HOM_0000072"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "in homeosis relationship with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_HOM0000065",
      "meta" : {
        "definition" : {
          "val" : "Similarity that is characterized by interchangeability in function.",
          "xrefs" : [ "http://dx.doi.org/10.1007/BF02814484", "http://dx.doi.org/10.1038/415741a", "http://purl.obolibrary.org/obo/HOM_0000065" ]
        },
        "synonyms" : [ {
          "pred" : "hasRelatedSynonym",
          "val" : "functional similarity",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/dc/elements/1.1/source",
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        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/HOM_0000065"
        }, {
          "pred" : "http://purl.org/dc/elements/1.1/creator",
          "val" : "http://bgee.unil.ch"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "in functional equivalence relationship with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_HOM0000062",
      "meta" : {
        "definition" : {
          "val" : "Historical homology that involves functional equivalent genes with retention of the ancestral function.",
          "xrefs" : [ "http://dx.doi.org/10.1093/nar/gkl1043", "http://purl.obolibrary.org/obo/HOM_0000062" ]
        },
        "comments" : [ "This may include examples of orthology, paralogy and xenology." ],
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "equivalogous to",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/HOM_0000062"
        }, {
          "pred" : "http://purl.org/dc/elements/1.1/creator",
          "val" : "http://bgee.unil.ch"
        }, {
          "pred" : "http://purl.org/dc/elements/1.1/source",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20116127"
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      },
      "type" : "PROPERTY",
      "lbl" : "in equivalogy relationship with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_HOM0000063",
      "meta" : {
        "definition" : {
          "val" : "Historical homology that involves orthologous pairs of interacting molecules in different organisms.",
          "xrefs" : [ "http://dx.doi.org/10.1101/gr.1774904", "http://dx.doi.org/10.1126/science.287.5450.116", "http://purl.obolibrary.org/obo/HOM_0000063" ]
        },
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "interologous to",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/dc/elements/1.1/source",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20116127"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/HOM_0000063"
        }, {
          "pred" : "http://purl.org/dc/elements/1.1/creator",
          "val" : "http://bgee.unil.ch"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "in interology relationship with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_HOM0000068",
      "meta" : {
        "definition" : {
          "val" : "Xenology that is characterized by multiple horizontal transfer events, resulting in the presence of two or more copies of the foreign gene in the host genome.",
          "xrefs" : [ "http://purl.obolibrary.org/obo/HOM_0000068", "http://www.ncbi.nlm.nih.gov/pubmed/3065587" ]
        },
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "multiple xenology",
          "xrefs" : [ ]
        }, {
          "pred" : "hasExactSynonym",
          "val" : "duplicate xenology",
          "xrefs" : [ ]
        }, {
          "pred" : "hasExactSynonym",
          "val" : "paraxenologous to",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/dc/elements/1.1/source",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20116127"
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          "val" : "http://bgee.unil.ch"
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          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/HOM_0000068"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "in paraxenology relationship with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_HOM0000069",
      "meta" : {
        "definition" : {
          "val" : "Paralogy that is characterized by extra similarity between paralogous sequences resulting from concerted evolution.",
          "xrefs" : [ "http://purl.obolibrary.org/obo/HOM_0000069", "http://www.ncbi.nlm.nih.gov/pubmed/3065587" ]
        },
        "comments" : [ "This phenomenon is usually due to gene conversion process." ],
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "plerologous to",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
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          "val" : "http://bgee.unil.ch"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/HOM_0000069"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "in plerology relationship with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_HOM0000066",
      "meta" : {
        "definition" : {
          "val" : "Biological homology that involves parts of the same organism.",
          "xrefs" : [ "http://dx.doi.org/10.1146/annurev.es.20.110189.000411", "http://purl.obolibrary.org/obo/HOM_0000066" ]
        },
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "iterative homologous to",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/dc/elements/1.1/source",
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        }, {
          "pred" : "http://purl.org/dc/elements/1.1/creator",
          "val" : "http://bgee.unil.ch"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "in iterative homology relationship with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_HOM0000060",
      "meta" : {
        "definition" : {
          "val" : "Between-species paralogy that involves single copy paralogs resulting from reciprocal gene loss.",
          "xrefs" : [ "http://dx.doi.org/10.1146/annurev.genet.39.073003.114725", "http://purl.obolibrary.org/obo/HOM_0000060", "http://www.ensembl.org/info/docs/compara/homology_method.html" ]
        },
        "comments" : [ "The genes are actually paralogs but appear to be orthologous due to differential, lineage-specific gene loss." ],
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "apparent 1:1 orthology",
          "xrefs" : [ ]
        }, {
          "pred" : "hasExactSynonym",
          "val" : "apparent orthologous to",
          "xrefs" : [ ]
        }, {
          "pred" : "hasExactSynonym",
          "val" : "1:1 paralogy",
          "xrefs" : [ ]
        }, {
          "pred" : "hasExactSynonym",
          "val" : "pseudoorthology",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
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        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/HOM_0000060"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "in apparent orthology relationship with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_HOM0000061",
      "meta" : {
        "definition" : {
          "val" : "Xenology that involves genes that ended up in a given genome as a result of a combination of vertical inheritance and horizontal gene transfer.",
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        },
        "comments" : [ "These genes may come out as paralogs in a single-genome analysis." ],
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "pseudoparalogous to",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/dc/elements/1.1/creator",
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          "val" : "http://purl.obolibrary.org/obo/HOM_0000061"
        }, {
          "pred" : "http://purl.org/dc/elements/1.1/source",
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      },
      "type" : "PROPERTY",
      "lbl" : "in pseudoparalogy relationship with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004096",
      "meta" : {
        "comments" : [ "DEPRECATED This relation is similar to but different in important respects to the characteristic-of relation. See comments on that relation for more information." ],
        "deprecated" : true
      },
      "type" : "PROPERTY",
      "lbl" : "DEPRECATED inheres in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_HOM0000048",
      "meta" : {
        "definition" : {
          "val" : "Orthology that involves two genes that experienced duplications more recent than the species split that created them.",
          "xrefs" : [ "http://dx.doi.org/10.1038/415741a", "http://purl.obolibrary.org/obo/HOM_0000048", "http://www.ensembl.org/info/docs/compara/homology_method.html" ]
        },
        "synonyms" : [ {
          "pred" : "hasRelatedSynonym",
          "val" : "co-orthology",
          "xrefs" : [ ]
        }, {
          "pred" : "hasRelatedSynonym",
          "val" : "trans-homology",
          "xrefs" : [ ]
        }, {
          "pred" : "hasExactSynonym",
          "val" : "many-to-many orthology",
          "xrefs" : [ ]
        }, {
          "pred" : "hasExactSynonym",
          "val" : "trans-orthology",
          "xrefs" : [ ]
        }, {
          "pred" : "hasExactSynonym",
          "val" : "many:many orthology",
          "xrefs" : [ ]
        }, {
          "pred" : "hasExactSynonym",
          "val" : "many to many orthologous to",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
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        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "before"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004025",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "disease causes dysfunction of (disease to anatomical entity)"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T03:58:20Z"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "disease causes dysfunction of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002088",
      "meta" : {
        "comments" : [ "Previously had ID  http://purl.obolibrary.org/obo/RO_0002123 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point.  No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line.  Official ID now chosen from DOS ID range." ],
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "during which starts"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004024",
      "meta" : {
        "definition" : {
          "val" : "A relationship between a disease and a process where the disease process disrupts the execution of the process.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T03:51:09Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "disease causes disruption of (disease to process)"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "disease causes disruption of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002089",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "starts before"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004027",
      "meta" : {
        "definition" : {
          "val" : "A relationship between a disease and an anatomical entity where the disease is triggered by an inflammatory response to stimuli occurring in the anatomical entity",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-12-26T19:37:31Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "disease has inflammation site"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004026",
      "meta" : {
        "definition" : {
          "val" : "A relationship between a disease and an anatomical entity where the disease has one or more features that are located in that entity.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "TODO: complete range axiom once more of CARO has been mireoted in to this ontology"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "This relation is intentionally very general, and covers isolated diseases, where the disease is realized as a process occurring in the location, and syndromic diseases, where one or more of the features may be present in that location. Thus any given disease can have multiple locations in the sense defined here."
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T04:06:02Z"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "disease has location"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004021",
      "meta" : {
        "definition" : {
          "val" : "A relation that holds between the disease and a process where the physical basis of the disease disrupts execution of a key biological process.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T03:37:52Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "disease has basis in disruption of (disease to process)"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "disease has basis in disruption of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002084",
      "meta" : {
        "comments" : [ "Previously had ID  http://purl.obolibrary.org/obo/RO_0002122 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point.  No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line.  Official ID now chosen from DOS ID range." ],
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "during which ends"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002085",
      "meta" : {
        "comments" : [ "Previously had ID  http://purl.obolibrary.org/obo/RO_0002124 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point.  No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line.  Official ID now chosen from DOS ID range." ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "di"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "encompasses"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004020",
      "meta" : {
        "definition" : {
          "val" : "A relation that holds between the disease and a material entity where the physical basis of the disease is a disorder of that material entity that affects its function.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "disease has basis in dysfunction of (disease to anatomical structure)"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T03:29:32Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "disease has basis in dysfunction of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004023",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all of which have a disease as the subject."
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T03:50:54Z"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "causal relationship with disease as subject"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002086",
      "meta" : {
        "comments" : [ "X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)" ],
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "ends after"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002087",
      "meta" : {
        "comments" : [ "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "starts_at_end_of"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "immediately preceded by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004022",
      "meta" : {
        "definition" : {
          "val" : "A relation that holds between the disease and a feature (a phenotype or other disease) where the physical basis of the disease is the feature.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T03:46:07Z"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "disease has basis in feature"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004018",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T03:20:29Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is basis for realizable"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004017",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T03:20:01Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "realizable has basis in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004019",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T03:26:47Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "disease has basis in"
    }, {
      "id" : "http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym",
      "type" : "PROPERTY",
      "lbl" : "has_broad_synonym"
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0005634",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000412",
          "val" : "http://purl.obolibrary.org/obo/go.owl"
        } ]
      },
      "type" : "CLASS",
      "lbl" : "nucleus"
    }, {
      "id" : "http://purl.obolibrary.org/obo/ro/subsets#ro-eco",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/subsets/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "eco subset"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004014",
      "meta" : {
        "definition" : {
          "val" : "Relates a gene to condition, such that a mutation in this gene is sufficient to produce the condition but that cannot be passed on to offspring[modified from orphanet].",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://www.orpha.net/ORDO/Orphanet_317344"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T02:57:07Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is causal somatic mutation in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004013",
      "meta" : {
        "definition" : {
          "val" : "Relates a gene to condition, such that a mutation in this gene is sufficient to produce the condition and that can be passed on to offspring[modified from orphanet].",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T02:56:40Z"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://www.orpha.net/ORDO/Orphanet_317343"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is causal germline mutation in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004016",
      "meta" : {
        "definition" : {
          "val" : "Relates a gene to condition, such that a mutation in this gene partially contributes to the presentation of this condition[modified from orphanet].",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T02:58:43Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://www.orpha.net/ORDO/Orphanet_317346"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is causal germline mutation partially giving rise to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004015",
      "meta" : {
        "definition" : {
          "val" : "Relates a gene to condition, such that a mutation in this gene predisposes to the development of a condition  and that is necessary but not sufficient to develop the condition[modified from orphanet].",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T02:57:43Z"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://www.orpha.net/ORDO/Orphanet_317345"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is causal susceptibility factor for"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004010",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is intended as a grouping for a more specific relations"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T02:53:08Z"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is genetic basis for condition"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004012",
      "meta" : {
        "definition" : {
          "val" : "Relates a gene to condition, such that a mutation in this gene in a germ cell impairs the function of the corresponding product and that is sufficient to produce the condition and that can be passed on to offspring[modified from orphanet].",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://www.orpha.net/ORDO/Orphanet_410295"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T02:56:06Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is causal loss of function germline mutation of in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004011",
      "meta" : {
        "definition" : {
          "val" : "Relates a gene to condition, such that a mutation in this gene in a germ cell provides a new function of the corresponding product and that is sufficient to produce the condition and that can be passed on to offspring[modified from orphanet].",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T02:55:51Z"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://www.orpha.net/ORDO/Orphanet_410296"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is causal gain of function germline mutation of in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004007",
      "meta" : {
        "definition" : {
          "val" : "p 'has primary input ot output' c iff either (a) p 'has primary input' c or (b) p 'has primary output' c.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology" ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2018-12-13T11:26:17Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has primary input or output"
    }, {
      "id" : "http://purl.obolibrary.org/obo/PATO_0002124",
      "type" : "CLASS",
      "lbl" : "laminar"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004006",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T02:46:57Z"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has partial material basis in germline mutation in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004009",
      "meta" : {
        "definition" : {
          "val" : "p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c.",
          "xrefs" : [ "GOC:cjm", "GOC:dph", "GOC:kva", "GOC:pt" ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology" ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2018-12-13T11:26:56Z"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has primary input"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004008",
      "meta" : {
        "definition" : {
          "val" : "p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c.",
          "xrefs" : [ "GOC:cjm", "GOC:dph", "GOC:kva", "GOC:pt" ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology" ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2018-12-13T11:26:32Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has primary output"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004003",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://www.orpha.net/ORDO/Orphanet_317343"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T02:45:54Z"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has material basis in germline mutation in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004002",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T02:45:37Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has material basis in loss of function germline mutation in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004005",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T02:46:26Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has major susceptibility factor"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004004",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T02:46:07Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://www.orpha.net/ORDO/Orphanet_317344"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has material basis in somatic mutation in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004001",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T02:45:20Z"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://www.orpha.net/ORDO/Orphanet_410296"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://www.orpha.net/ORDO/Orphanet_410295"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has material basis in gain of function germline mutation in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0004000",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-11-05T02:38:20Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is intended as a grouping for a more specific relations"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "condition has genetic basis in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0016772",
      "type" : "CLASS",
      "lbl" : "transferase activity, transferring phosphorus-containing groups"
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000141",
      "type" : "CLASS",
      "lbl" : "immaterial entity"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002170",
      "meta" : {
        "definition" : {
          "val" : "a is connected to b if and only if a and b are discrete structure, and there exists some connecting structure c, such that c connects a and b",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/22293552"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://github.com/obophenotype/uberon/wiki/Connectivity-Design-Pattern"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "a 'toe distal phalanx bone' that is connected to a 'toe medial phalanx bone' (an interphalangeal joint *connects* these two bones)."
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://github.com/obophenotype/uberon/wiki/Modeling-articulations-Design-Pattern"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "connected to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002171",
      "meta" : {
        "definition" : {
          "val" : "A is mutually_spatially_disjoint_with B if both A and B are classes, and there exists no p such that p is part_of some A and p is part_of some B.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "non-overlapping with"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://github.com/obophenotype/uberon/wiki/Part-disjointness-Design-Pattern"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000425",
          "val" : "Class: <http://www.w3.org/2002/07/owl#Nothing> EquivalentTo: (BFO_0000050 some ?X) and (BFO_0000050 some ?Y)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/22293552"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "shares no parts with"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/RO_0002163"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "mutually spatially disjoint with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002176",
      "meta" : {
        "definition" : {
          "val" : "c connects a if and only if there exist some b such that a and b are similar parts of the same system, and c connects b, specifically, c connects a with b. When one structure connects two others it unites some aspect of the function or role they play within the system.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "The M8 connects Glasgow and Edinburgh"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/22293552"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://github.com/obophenotype/uberon/wiki/Connectivity-Design-Pattern"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "a 'toe distal phalanx bone' that is connected to a 'toe medial phalanx bone' (an interphalangeal joint *connects* these two bones)."
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://github.com/obophenotype/uberon/wiki/Modeling-articulations-Design-Pattern"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "connects"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002177",
      "meta" : {
        "definition" : {
          "val" : "a is attached to part of b if a is attached to b, or a is attached to some p, where p is part of b.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "attached to part of (anatomical structure to anatomical structure)"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "attached to part of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002178",
      "meta" : {
        "definition" : {
          "val" : "Relation between an arterial structure and another structure, where the arterial structure acts as a conduit channeling fluid, substance or energy.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Individual ontologies should provide their own constraints on this abstract relation. For example, in the realm of anatomy this should hold between an artery and an anatomical structure"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20064205"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "supplies"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002179",
      "meta" : {
        "definition" : {
          "val" : "Relation between an collecting structure and another structure, where the collecting structure acts as a conduit channeling fluid, substance or energy away from the other structure.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Individual ontologies should provide their own constraints on this abstract relation. For example, in the realm of anatomy this should hold between a vein and an anatomical structure"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20064205"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "drains"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002172",
      "meta" : {
        "definition" : {
          "val" : "An assertion that holds between an ontology class and an organism taxon class, which is intepreted to yield some relationship between instances of the ontology class and the taxon.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://github.com/obophenotype/uberon/wiki/Taxon-constraints"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "taxonomic class assertion"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002173",
      "meta" : {
        "definition" : {
          "val" : "S ambiguous_for_taxon T if the class S does not have a clear referent in taxon T. An example would be the class 'manual digit 1', which encompasses a homology hypotheses that is accepted for some species (e.g. human and mouse), but does not have a clear referent in Aves - the referent is dependent on the hypothesis embraced, and also on the ontogenetic stage.  [PHENOSCPAE:asilomar_mtg]",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://github.com/obophenotype/uberon/wiki/Taxon-constraints"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "ambiguous for taxon"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002174",
      "meta" : {
        "definition" : {
          "val" : "S dubious_for_taxon T if it is probably the case that no instances of S can be found in any instance of T.",
          "xrefs" : [ ]
        },
        "comments" : [ "This relation lacks a strong logical interpretation, but can be used in place of never_in_taxon where it is desirable to state that the definition of the class is too strict for the taxon under consideration, but placing a never_in_taxon link would result in a chain of inconsistencies that will take ongoing coordinated effort to resolve. Example: metencephalon in teleost" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/22293552"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://github.com/obophenotype/uberon/wiki/Taxon-constraints"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "dubious for taxon"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002175",
      "meta" : {
        "definition" : {
          "val" : "S present_in_taxon T if some instance of T has some S. This does not means that all instances of T have an S - it may only be certain life stages or sexes that have S",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://github.com/obophenotype/uberon/wiki/Taxon-constraints"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "https://orcid.org/0000-0002-6601-2165"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/22293552"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "present in taxon"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002160",
      "meta" : {
        "definition" : {
          "val" : "x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://github.com/obophenotype/uberon/wiki/Taxon-constraints"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "lactation SubClassOf 'only in taxon' some 'Mammalia'"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/17921072"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "The original intent was to treat this as a macro that expands to 'in taxon' only ?Y - however, this is not necessary if we instead have supplemental axioms that state that each pair of sibling tax have a disjointness axiom using the 'in taxon' property - e.g.\n\n 'in taxon' some Eukaryota DisjointWith 'in taxon' some Eubacteria"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20973947"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "only in taxon"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002161",
      "meta" : {
        "definition" : {
          "val" : "x never in taxon T if and only if T is a class, and x does not instantiate the class expression \"in taxon some T\". Note that this is a shortcut relation, and should be used as a hasValue restriction in OWL.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20973947"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000425",
          "val" : "?X DisjointWith RO_0002162 some ?Y "
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/17921072"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://github.com/obophenotype/uberon/wiki/Taxon-constraints"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "tooth SubClassOf 'never in taxon' value 'Aves'"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "never in taxon"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002162",
      "meta" : {
        "definition" : {
          "val" : "x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed.",
          "xrefs" : [ ]
        },
        "comments" : [ "Connects a biological entity to its taxon of origin." ],
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Jennifer Deegan"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20973947"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/17921072"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://github.com/obophenotype/uberon/wiki/Taxon-constraints"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "in taxon"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002163",
      "meta" : {
        "definition" : {
          "val" : "A is spatially_disjoint_from B if and only if they have no parts in common",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000424",
          "val" : "BFO_0000051 exactly 0 (BFO_0000050 some ?Y)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Note that it would be possible to use the relation to label the relationship between a near infinite number of structures - between the rings of saturn and my left earlobe. The intent is that this is used for parsiomoniously for disambiguation purposes - for example, between siblings in a jointly exhaustive pairwise disjointness hierarchy"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "There are two ways to encode this as a shortcut relation. The other possibility to use an annotation assertion between two classes, and expand this to a disjointness axiom. "
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://github.com/obophenotype/uberon/wiki/Part-disjointness-Design-Pattern"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/22293552"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "spatially disjoint from"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002158",
      "meta" : {
        "definition" : {
          "val" : "two individual entities d1 and d2 stand in a shares_ancestor_with relation if and only if there exists some a such that d1 derived_by_descent_from a and d2 derived_by_descent_from a.",
          "xrefs" : [ ]
        },
        "comments" : [ "VBO calls this homologous_to" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Consider obsoleting and merging with child relation, 'in homology relationship with'"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "shares ancestor with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002159",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "serially homologous to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0003002",
      "meta" : {
        "definition" : {
          "val" : "Holds between entity A (a transcription factor) and a nucleic acid B if and only if A down-regulates the expression of B. The nucleic acid can be a gene or an mRNA.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Vasundra Touré"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "represses expression of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0003001",
      "meta" : {
        "definition" : {
          "val" : "a produced_by b iff some process that occurs_in b has_output a.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Melissa Haendel"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "produced by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002156",
      "meta" : {
        "definition" : {
          "val" : "d derived_by_descent_from a if d is specified by some genetic program that is sequence-inherited-from a genetic program that specifies a.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "evolutionarily_descended_from"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "ancestral_stucture_of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "derived by descent from"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0003003",
      "meta" : {
        "definition" : {
          "val" : "Holds between entity A (a transcription factor) and nucleic acid B if and only if A up-regulates the expression of B. The nucleic acid can be a gene or mRNA.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Vasundra Touré"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "increases expression of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002157",
      "meta" : {
        "definition" : {
          "val" : "inverse of derived by descent from",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has derived by descendant"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002150",
      "meta" : {
        "definition" : {
          "val" : "X continuous_with Y if and only if X and Y share a fiat boundary.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "The label for this relation was previously connected to. I relabeled this to \"continuous with\". The standard notion of connectedness does not imply shared boundaries - e.g. Glasgow connected_to Edinburgh via M8; my patella connected_to my femur (via patellar-femoral joint)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "connected to"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "FMA:85972"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "continuous with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002151",
      "meta" : {
        "definition" : {
          "val" : "x partially overlaps y iff there exists some z such that z is part of x and z is part of y, and it is also the case that neither x is part of y or y is part of x",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000426",
          "val" : "(forall (?x ?y) \n\t(iff \n\t\t(proper_overlaps ?x ?y)\n\t\t(and \n\t\t\t(overlaps ?x ?y)\n\t\t\t(not (part_of ?x ?y)) \n\t\t\t(not (part_of ?y ?x)))))"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "proper overlaps"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "We would like to include disjointness axioms with part_of and has_part, however this is not possible in OWL2 as these are non-simple properties and hence cannot appear in a disjointness axiom"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "partially overlaps"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0003000",
      "meta" : {
        "definition" : {
          "val" : "a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix.",
          "xrefs" : [ ]
        },
        "comments" : [ "Note that this definition doesn't quite distinguish the output of a transformation process from a production process, which is related to the identity/granularity issue." ],
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Melissa Haendel"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "produces"
    }, {
      "id" : "http://purl.obolibrary.org/obo/PATO_0000141",
      "type" : "CLASS",
      "lbl" : "structure"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000412",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "imported from"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002380",
      "meta" : {
        "definition" : {
          "val" : "x is a branching part of y if and only if x is part of y and x is connected directly or indirectly to the main stem of y",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "FMA:85994"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "branching part of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0100001",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "term replaced by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002385",
      "meta" : {
        "definition" : {
          "val" : "x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has potential to developmentally contribute to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002386",
      "meta" : {
        "definition" : {
          "val" : "x has potential to developmentally induce y iff x developmentally induces y or x is capable of developmentally inducing y",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has potential to developmentally induce"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002387",
      "meta" : {
        "definition" : {
          "val" : "x has the potential to develop into y iff x develops into y or if x is capable of developing into y",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has potential to develop into"
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0043005",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000412",
          "val" : "http://purl.obolibrary.org/obo/go.owl"
        } ]
      },
      "type" : "CLASS",
      "lbl" : "neuron projection"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002388",
      "meta" : {
        "definition" : {
          "val" : "x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has potential to directly develop into"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002381",
      "meta" : {
        "definition" : {
          "val" : "x main_stem_of y if y is a branching structure and x is a channel that traces a linear path through y, such that x has higher capacity than any other such path.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "main stem of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002382",
      "meta" : {
        "definition" : {
          "val" : "x proper_distributary_of y iff x distributary_of y and x does not flow back into y",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "proper distributary of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002383",
      "meta" : {
        "definition" : {
          "val" : "x proper_tributary_of y iff x tributary_of y and x does not originate from y",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "proper tributary of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002384",
      "meta" : {
        "definition" : {
          "val" : "x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction).",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has developmental potential involving"
    }, {
      "id" : "http://purl.obolibrary.org/obo/PATO_0001241",
      "type" : "CLASS",
      "lbl" : "physical object quality"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002378",
      "meta" : {
        "definition" : {
          "val" : "x anabranch_of y if x is a distributary of y (i.e. it channels a from a larger flow from y) and x ultimately channels the flow back into y.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "anastomoses with"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "anabranch of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002379",
      "meta" : {
        "definition" : {
          "val" : "x spatially_coextensive_with y if and inly if x and y have the same location",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "A lump of clay and a statue"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "This relation is added for formal completeness. It is unlikely to be used in many practical scenarios"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "spatially coextensive with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000424",
      "type" : "PROPERTY",
      "lbl" : "expand expression to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000425",
      "type" : "PROPERTY",
      "lbl" : "expand assertion to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/CARO_0000000",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000412",
          "val" : "http://purl.obolibrary.org/obo/caro.owl"
        } ]
      },
      "type" : "CLASS",
      "lbl" : "anatomical entity"
    }, {
      "id" : "http://purl.obolibrary.org/obo/CARO_0000003",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000412",
          "val" : "http://purl.obolibrary.org/obo/caro.owl"
        } ]
      },
      "type" : "CLASS",
      "lbl" : "connected anatomical structure"
    }, {
      "id" : "http://purl.obolibrary.org/obo/CARO_0000007",
      "type" : "CLASS",
      "lbl" : "immaterial anatomical entity"
    }, {
      "id" : "http://purl.obolibrary.org/obo/CARO_0000006",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000412",
          "val" : "http://purl.obolibrary.org/obo/caro.owl"
        } ]
      },
      "type" : "CLASS",
      "lbl" : "material anatomical entity"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002374",
      "meta" : {
        "definition" : {
          "val" : "x has_fused_element y iff: there exists some z : x has_part z, z homologous_to y, and y is a distinct element, the boundary between x and z is largely fiat",
          "xrefs" : [ ]
        },
        "comments" : [ "A has_fused_element B does not imply that A has_part some B: rather than A has_part some B', where B' that has some evolutionary relationship to B." ],
        "synonyms" : [ {
          "pred" : "hasBroadSynonym",
          "val" : "has fused element",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/22293552"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "false"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "derived from ancestral fusion of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002132",
      "meta" : {
        "definition" : {
          "val" : "The relation between a neuron projection bundle and a neuron projection that is fasciculated with it.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000426",
          "val" : "(forall (?x ?y) \n\t(iff \n\t\t(has_fasciculating_neuron_projection ?x ?y)\n\t\t(exists (?nps ?npbs)\t\t\n\t\t\t(and \n\t\t\t\t(\"neuron projection bundle ; CARO_0001001\" ?x)\n\t\t\t\t(\"neuron projection ; GO0043005\" ?y)\n\t\t\t\t(\"neuron projection segment ; CARO_0001502\" ?nps)\n\t\t\t\t(\"neuron projection bundle segment ; CARO_0001500\" ?npbs)\n\t\t\t\t(part_of ?nps ?y)\n\t\t\t\t(part_of ?npbs ?x)\n\t\t\t\t(part_of ?nps ?npbs)\n\t\t\t\t(forall (?npbss)\n\t\t\t\t\t(if\n\t\t\t\t\t\t(and \n\t\t\t\t\t\t\t(\"neuron projection bundle subsegment ; CARO_0001501\" ?npbss)\n\t\t\t\t\t\t\t(part_of ?npbss ?npbs) \n\t\t\t\t\t\t)\n\t\t\t\t\t\t(overlaps ?nps ?npbss)\n\t\t\t\t\t))))))\n\n\n"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        }, {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/22402613"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has fasciculating component"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has fasciculating neuron projection"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002375",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds between two material entities in a system of connected structures, where the branching relationship holds based on properties of the connecting network.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://github.com/obophenotype/uberon/issues/170"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "This relation can be used for geographic features (e.g. rivers) as well as anatomical structures (plant branches and roots, leaf veins, animal veins, arteries, nerves)"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/branching_part_of.png"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving branching relationships"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "in branching relationship with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002376",
      "meta" : {
        "definition" : {
          "val" : "x tributary_of y if and only if x a channel for the flow of a substance into y, where y is larger than x. If x and y are hydrographic features, then y is the main stem of a river, or a lake or bay, but not the sea or ocean. If x and y are anatomical, then y is a vein.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "drains to"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://en.wikipedia.org/wiki/Tributary"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "drains into"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "inferior epigastric vein tributary_of external iliac vein"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "This relation can be used for geographic features (e.g. rivers) as well as anatomical structures (veins, arteries)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.medindia.net/glossary/venous_tributary.htm"
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          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "Deschutes River tributary_of Columbia River"
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          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://dbpedia.org/ontology/drainsTo"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "tributary channel of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://en.wikipedia.org/wiki/Tributary"
        } ]
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      "type" : "PROPERTY",
      "lbl" : "tributary of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002134",
      "meta" : {
        "definition" : {
          "val" : "Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input.\nT innervates some R\nExpands_to: T has_fasciculating_neuron_projection that synapse_in some R.",
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          "pred" : "http://purl.obolibrary.org/obo/IAO_0000424",
          "val" : "<http://purl.obolibrary.org/obo/RO_0002132> some (<http://purl.obolibrary.org/obo/GO_0043005> that (<http://purl.obolibrary.org/obo/RO_0002131> some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)))"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "innervates"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002377",
      "meta" : {
        "definition" : {
          "val" : "x distributary_of y if and only if x is capable of channeling the flow of a substance to y, where y channels less of the substance than x",
          "xrefs" : [ ]
        },
        "comments" : [ "This is both a mereotopological relationship and a relationship defined in connection to processes. It concerns both the connecting structure, and how this structure is disposed to causally affect flow processes" ],
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
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          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
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          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://en.wikipedia.org/wiki/Distributary"
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          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "distributary channel of"
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          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "Deschutes River distributary_of Little Lava Lake"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "distributary of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002371",
      "meta" : {
        "definition" : {
          "val" : "a is attached to b if and only if a and b are discrete objects or object parts, and there are physical connections between a and b such that a force pulling a will move b, or a force pulling b will move a",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
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          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "attached to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002372",
      "meta" : {
        "definition" : {
          "val" : "m has_muscle_origin s iff m is attached_to s, and it is the case that when m contracts, s does not move. The site of the origin tends to be more proximal and have greater mass than what the other end attaches to.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
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          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "Wikipedia:Insertion_(anatomy)"
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          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
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        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has muscle origin"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002130",
      "meta" : {
        "definition" : {
          "val" : "A general relation between a neuron and some structure in which it either chemically synapses to some target or in which it receives (chemical) synaptic input.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
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          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has synapse in"
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          "pred" : "http://purl.obolibrary.org/obo/IAO_0000424",
          "val" : "<http://purl.obolibrary.org/obo/RO_0002131> some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)"
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          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/22402613"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
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        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has synaptic terminal in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002131",
      "meta" : {
        "definition" : {
          "val" : "x overlaps y if and only if there exists some z such that x has part z and z part of y",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
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          "pred" : "http://purl.obolibrary.org/obo/IAO_0000424",
          "val" : "http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "overlaps"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002373",
      "meta" : {
        "definition" : {
          "val" : "m has_muscle_insertion s iff m is attaches_to s, and it is the case that when m contracts, s moves. Insertions are usually connections of muscle via tendon to bone.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
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        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has muscle insertion"
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      "id" : "http://purl.obolibrary.org/obo/ENVO_00000428",
      "type" : "CLASS",
      "lbl" : "biome"
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      "id" : "http://purl.obolibrary.org/obo/CARO_0000011",
      "type" : "CLASS",
      "lbl" : "connected anatomical system"
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0016020",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000412",
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        } ]
      },
      "type" : "CLASS",
      "lbl" : "membrane"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002121",
      "meta" : {
        "definition" : {
          "val" : "Relation between a neuron and some structure  (e.g.- a brain region) in which its dendrite receives synaptic input.\n\n\t",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
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          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
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          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "dendrite synapsed in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0045202",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000412",
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        } ]
      },
      "type" : "CLASS",
      "lbl" : "synapse"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002360",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/dc/terms/source",
          "val" : "http://neurolex.org/wiki/Property:DendriteLocation"
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          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
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        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has dendrite location"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002120",
      "meta" : {
        "definition" : {
          "val" : " Relation between a neuron and an anatomical structure (including cells) that it chemically synapses to.\n        ",
          "xrefs" : [ ]
        },
        "comments" : [ "N1 synapsed_to some N2 \nExpands to:\nN1 SubclassOf ( \n   has_part some (\n      ‘pre-synaptic membrane ; GO:0042734’ that part_of some ( \n\t‘synapse ; GO:0045202’ that has_part some (\n\t   ‘post-synaptic membrane ; GO:0045211’ that part_of some N2))))" ],
        "basicPropertyValues" : [ {
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          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
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          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "synapsed to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002356",
      "meta" : {
        "definition" : {
          "val" : "The relationship linking a cell and its participation in a process that results in the fate of the cell being specified. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. ",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
        "basicPropertyValues" : [ {
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        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.geneontology.org/GO.doc.development.shtml#fate"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "results in specification of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002114",
      "meta" : {
        "definition" : {
          "val" : "A relation between a motor neuron and a muscle that it synapses to via a type III bouton.",
          "xrefs" : [ ]
        },
        "comments" : [ "Expands to: has_part some ('type III terminal button' that has_part some ('pre-synaptic membrane' that part_of some ('synapse' that has_part some ('post-synaptic membrane' that part_of some ?Y))))" ],
        "basicPropertyValues" : [ {
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          "val" : "BFO_0000051 some (GO_0061177 that BFO_0000051 some (that BFO_0000051 some (GO_0097467 that BFO_0000051 some ( that BFO_0000050 some ?Y))))"
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          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
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        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "synapsed_via_type_III_bouton_to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0001025",
      "meta" : {
        "definition" : {
          "val" : "a relation between two independent continuants, the target and the location, in which the target is entirely within the location",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
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        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "located in"
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          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "located_in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "my brain is located in my head"
        }, {
          "pred" : "http://purl.org/dc/elements/1.1/source",
          "val" : "http://www.obofoundry.org/ro/#OBO_REL:located_in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this rat is located in this cage"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "located in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002598",
      "meta" : {
        "definition" : {
          "val" : "Holds between c and p if and only if c is capable of some activity a, and a positively regulates p.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
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          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "renin -> arteriolar smooth muscle contraction"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "capable of positively regulating"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002115",
      "meta" : {
        "definition" : {
          "val" : "Relation between a muscle and a motor neuron that synapses to it via a type III bouton.\n",
          "xrefs" : [ ]
        },
        "comments" : [ "Expands to: has_part some ('presynaptic membrane' that part_of some ('synapse' that has_part some ('type III terminal button' that has_part some 'postsynaptic membrane' that part_of some ?Y)))))" ],
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        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "synapsed_by_via_type_III_bouton"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002357",
      "meta" : {
        "definition" : {
          "val" : "p results in developmental induction of c if and only if p is a collection of cell-cell signaling processes that signal to a neighbouring tissue that is the precursor of the mature c, where the signaling results in the commitment to cell types necessary for the formation of c.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "results in developmental induction of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002599",
      "meta" : {
        "definition" : {
          "val" : "Holds between a material entity c and a pathological process p if and only if c is capable of some activity a, where a inhibits p.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "treats"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "The entity c may be a molecular entity with a drug role, or it could be some other entity used in a therapeutic context, such as a hyperbaric chamber."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "pazopanib -> pathological angiogenesis"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "capable of inhibiting or preventing pathological process"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000600",
      "type" : "PROPERTY",
      "lbl" : "elucidation"
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0019787",
      "type" : "CLASS",
      "lbl" : "small conjugating protein ligase activity"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002110",
      "meta" : {
        "definition" : {
          "val" : "Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input. ",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        }, {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/22402613"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "synapsed in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000424",
          "val" : "http://purl.obolibrary.org/obo/BFO_0000051 some (\n   http://purl.org/obo/owl/GO#GO_0045211 and http://purl.obolibrary.org/obo/BFO_0000050 some (\n      http://purl.org/obo/owl/GO#GO_0045202 and http://purl.obolibrary.org/obo/BFO_0000050 some ?Y))"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has postsynaptic terminal in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0001021",
      "meta" : {
        "definition" : {
          "val" : "A relation between a material entity and a condition (a phenotype or disease) of a host, in which the material entity is part of the host itself, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "is autoimmune trigger for"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002594",
      "meta" : {
        "definition" : {
          "val" : "An annotation property that connects an object property to a class, where the object property is derived from or a shortcut property for the class. The exact semantics of this annotation may vary on a case by case basis.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "is relational form of a class"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002352",
      "meta" : {
        "definition" : {
          "val" : "inverse of has input",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco", "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "input of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002111",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has neurotransmitter"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "releases neurotransmitter"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002595",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "causal relation between material entity and a process"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002353",
      "meta" : {
        "definition" : {
          "val" : "inverse of has output",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco", "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "output of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0001022",
      "meta" : {
        "definition" : {
          "val" : "A relation between a condition (a phenotype or disease) of a host and a material entity, in which the material entity is not part of the host, and is considered harmless to non-allergic hosts, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "penicillin allergy (DOID:0060520) has allergic trigger penicillin (CHEBI:17334)"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has allergic trigger"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002112",
      "meta" : {
        "definition" : {
          "val" : "Relation between a muscle and a motor neuron that synapses to it via a type Is bouton.",
          "xrefs" : [ ]
        },
        "comments" : [ "Expands to: has_part some ('presynaptic membrane' that part_of some ('synapse' that has_part some ('type Is terminal button' that has_part some 'postsynaptic membrane' that part_of some ?Y)))))" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/22402613"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000424",
          "val" : "BFO_0000051 some (GO_0042734 that BFO_0000050 some (GO_0045202 that BFO_0000051 some (GO_0061177 that BFO_0000051 some GO_0045211 that BFO_0000050 some ?Y)))"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Marta Costa"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "synapsed_by_via_type_Is_bouton"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002596",
      "meta" : {
        "definition" : {
          "val" : "Holds between c and p if and only if c is capable of some activity a, and a regulates p.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "pyrethroid -> growth"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "capable of regulating"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002354",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "formed as result of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0001023",
      "meta" : {
        "definition" : {
          "val" : "A relation between a condition (a phenotype or disease) of a host and a material entity, in which the material entity is part of the host itself, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "has autoimmune trigger"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002113",
      "meta" : {
        "definition" : {
          "val" : "Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/22402613"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000424",
          "val" : "<http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0042734> that <http://purl.obolibrary.org/obo/BFO_0000050> some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "synapses in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has presynaptic terminal in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002597",
      "meta" : {
        "definition" : {
          "val" : "Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "capable of negatively regulating"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002355",
      "meta" : {
        "definition" : {
          "val" : "A relationship between a process and an anatomical entity such that the process contributes to the act of creating the structural organization of the anatomical entity.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "results in structural organization of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0045211",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000412",
          "val" : "http://purl.obolibrary.org/obo/go.owl"
        } ]
      },
      "type" : "CLASS",
      "lbl" : "postsynaptic membrane"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002590",
      "type" : "PROPERTY",
      "lbl" : "results in disassembly of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002591",
      "type" : "PROPERTY",
      "lbl" : "results in remodeling of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002350",
      "meta" : {
        "definition" : {
          "val" : "is member of is a mereological relation between a item and a collection.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "SIO"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is member of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "member part of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "An organism that is a member of a population of organisms"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "member of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002592",
      "meta" : {
        "definition" : {
          "val" : "p results in organization of c iff p results in the assembly, arrangement of constituent parts, or disassembly of c",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "results in organization of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0001020",
      "meta" : {
        "definition" : {
          "val" : "A relation between a material entity and a condition (a phenotype or disease) of a host, in which the material entity is not part of the host, and is considered harmless to non-allergic hosts, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "penicillin (CHEBI:17334) is allergic trigger for penicillin allergy (DOID:0060520)"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is allergic trigger for"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002351",
      "meta" : {
        "definition" : {
          "val" : "has member is a mereological relation between a collection and an item.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "SIO"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has member"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002593",
      "meta" : {
        "definition" : {
          "val" : "holds between x and y if and only if the time point at which x ends is equivalent to the time point at which y starts. Formally: iff ω(x) = α(y).",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "existence ends at start of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002107",
      "meta" : {
        "definition" : {
          "val" : "A relation between a motor neuron and a muscle that it synapses to via a type II bouton.",
          "xrefs" : [ ]
        },
        "comments" : [ "Expands to: has_part some ('type II terminal button' that has_part some ('pre-synaptic membrane' that part_of some ('synapse' that has_part some ('post-synaptic membrane' that part_of some ?Y))))" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Marta Costa"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000424",
          "val" : "BFO_0000051 some (GO_0061175 that BFO_0000051 some (that BFO_0000051 some (GO_0045202 that BFO_0000051 some ( that BFO_0000050 some ?Y))))"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "synapsed_via_type_II_bouton_to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0001018",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Intended meaning:\ndomain: material entity\nrange: spatial region or site (immaterial continuant)\n        "
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "contained_in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "contained in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Containment is location not involving parthood, and arises only where some immaterial continuant is involved."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Containment obtains in each case between material and immaterial continuants, for instance: lung contained_in thoracic cavity; bladder contained_in pelvic cavity. Hence containment is not a transitive relation.    If c part_of c1 at t then we have also, by our definition and by the axioms of mereology applied to spatial regions, c located_in c1 at t. Thus, many examples of instance-level location relations for continuants are in fact cases of instance-level parthood. For material continuants location and parthood coincide. Containment is location not involving parthood, and arises only where some immaterial continuant is involved. To understand this relation, we first define overlap for continuants as follows:    c1 overlap c2 at t =def for some c, c part_of c1 at t and c part_of c2 at t. The containment relation on the instance level can then be defined (see definition):"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "contained in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002349",
      "meta" : {
        "definition" : {
          "val" : "p 'results in determination of' c if and only if p is a developmental process and c is a cell and p results in the state of c changing to be determined. Once a cell becomes determined, it becomes committed to differentiate down a particular pathway regardless of its environment.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.geneontology.org/GO.doc.development.shtml#fate"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "results in determination of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0001019",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "contains"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "contains"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002108",
      "meta" : {
        "definition" : {
          "val" : "Relation between a muscle and a motor neuron that synapses to it via a type II bouton.",
          "xrefs" : [ ]
        },
        "comments" : [ "Expands to: has_part some ('presynaptic membrane' that part_of some ('synapse' that has_part some ('type II terminal button' that has_part some 'postsynaptic membrane' that part_of some ?Y)))))" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000424",
          "val" : "BFO_0000051 some (GO_0042734 that BFO_0000050 some (GO_0045202 that BFO_0000051 some (GO_0061174 that BFO_0000051 some GO_0045211 that BFO_0000050 some ?Y)))\n"
        }, {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/22402613"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Marta Costa"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "synapsed_by_via_type_II_bouton"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002109",
      "meta" : {
        "definition" : {
          "val" : "Relation between a muscle and a motor neuron that synapses to it via a type Ib bouton.",
          "xrefs" : [ ]
        },
        "comments" : [ "Expands to: has_part some ('presynaptic membrane' that part_of some ('synapse' that has_part some ('type Ib terminal button' that has_part some 'postsynaptic membrane' that part_of some ?Y)))))" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000424",
          "val" : "BFO_0000051 some (GO_0042734 that BFO_0000050 some (GO_0045202 that BFO_0000051 some (GO_0061176 that BFO_0000051 some GO_0045211 that BFO_0000050 some ?Y)))"
        }, {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/22402613"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Marta Costa"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "David Osumi-Sutherland"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "synapsed_by_via_type_Ib_bouton"
    }, {
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      "lbl" : "shorthand"
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      "meta" : {
        "definition" : {
          "val" : "Relation between an anatomical structure (including cells) and a neuron that chemically synapses to it. ",
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        },
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      "type" : "PROPERTY",
      "lbl" : "synapsed by"
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      "id" : "http://purl.obolibrary.org/obo/RO_0002345",
      "meta" : {
        "definition" : {
          "val" : "Holds between p and c when p is a transportation or localization process and the outcome of this process is to move c to a destination that is part of some s, where the end location of c is part of the region that surrounds s.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology" ],
        "basicPropertyValues" : [ {
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      },
      "type" : "PROPERTY",
      "lbl" : "exports"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002587",
      "type" : "PROPERTY",
      "lbl" : "results in synthesis of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002588",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension" ]
      },
      "type" : "PROPERTY",
      "lbl" : "results in assembly of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002104",
      "meta" : {
        "definition" : {
          "val" : "Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part.",
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        },
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          "val" : "Alexander Diehl"
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          "val" : "Lindsay Cowell"
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      "type" : "PROPERTY",
      "lbl" : "has plasma membrane part"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0001015",
      "meta" : {
        "definition" : {
          "val" : "a relation between two independent continuants, the location and the target, in which the target is entirely within the location",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
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          "val" : "my head is the location of my brain"
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          "val" : "Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/"
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          "val" : "location_of"
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          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this cage is the location of this rat"
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          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
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          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "is location of"
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      },
      "type" : "PROPERTY",
      "lbl" : "location of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002589",
      "meta" : {
        "definition" : {
          "val" : "p results in catabolism of c if and only if p is a catabolic process, and the execution of p results in c being broken into smaller parts with energy being released.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "results in catabolism of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002105",
      "meta" : {
        "definition" : {
          "val" : "A relation between a motor neuron and a muscle that it synapses to via a type Ib bouton.",
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        },
        "comments" : [ "Expands to: has_part some ('type Ib terminal button' that has_part some ('pre-synaptic membrane' that part_of some ('synapse' that has_part some ('post-synaptic membrane' that part_of some ?Y))))" ],
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      },
      "type" : "PROPERTY",
      "lbl" : "synapsed_via_type_Ib_bouton_to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002348",
      "meta" : {
        "definition" : {
          "val" : "p 'results in commitment to' c if and only if p is a developmental process and c is a cell and p results in the state of c changing such that is can only develop into a single cell type.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology" ],
        "basicPropertyValues" : [ {
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          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "an annotation of gene X to cell commitment with results_in_commitment_to CL:0000540 (neuron) means that at the end of the process an unspecified cell has been specified and determined to develop into a neuron."
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          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "results in commitment to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002106",
      "meta" : {
        "definition" : {
          "val" : "A relation between a motor neuron and a muscle that it synapses to via a type Is bouton.",
          "xrefs" : [ ]
        },
        "comments" : [ "Expands to: has_part some ('type Is terminal button' that has_part some ('pre-synaptic membrane' that part_of some ('synapse' that has_part some ('post-synaptic membrane' that part_of some ?Y))))" ],
        "basicPropertyValues" : [ {
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      },
      "type" : "PROPERTY",
      "lbl" : "synapsed_via_type_Is_bouton_to"
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      "id" : "http://purl.obolibrary.org/obo/RO_0002341",
      "meta" : {
        "definition" : {
          "val" : "Holds between p and l when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that is aligned_with l ",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
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      },
      "type" : "PROPERTY",
      "lbl" : "results in transport along"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002583",
      "meta" : {
        "definition" : {
          "val" : "holds between x and y if and only if the time point at which x starts is equivalent to the time point at which y ends. Formally: iff α(x) = ω(y).",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "existence starts at end of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002584",
      "meta" : {
        "definition" : {
          "val" : "s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
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          "val" : "gland SubClassOf 'has part structure that is capable of' some 'secretion by cell'"
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      },
      "type" : "PROPERTY",
      "lbl" : "has part structure that is capable of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002100",
      "meta" : {
        "definition" : {
          "val" : "Relation between a neuron and an anatomical structure that its soma is part of.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
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      },
      "type" : "PROPERTY",
      "lbl" : "has soma location"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002342",
      "meta" : {
        "definition" : {
          "val" : "Holds between p and m when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that crosses m.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology" ],
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      },
      "type" : "PROPERTY",
      "lbl" : "results in transport across"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002101",
      "meta" : {
        "definition" : {
          "val" : "relationship between a neuron and a neuron projection bundle (e.g.- tract or nerve bundle) that one or more of its projections travels through.\n",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
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        }, {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/22402613"
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          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
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          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
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          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "fasciculates with"
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      "id" : "http://purl.obolibrary.org/obo/RO_0002343",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "'pollen tube growth' results_in growth_of some 'pollen tube'"
        }, {
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        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "results in growth of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002585",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "p 'results in closure of' c if and only if p is a developmental process and p results in a state of c changing from open to closed."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "results in closure of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002586",
      "meta" : {
        "definition" : {
          "val" : "p results in breakdown of c if and only if the execution of p leads to c no longer being present at the end of p",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "results in breakdown of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002344",
      "meta" : {
        "basicPropertyValues" : [ {
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          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "'mitochondrial transport' results_in_transport_to_from_or_in some  mitochondrion (GO:0005739)"
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      },
      "type" : "PROPERTY",
      "lbl" : "results in transport to from or in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002102",
      "meta" : {
        "definition" : {
          "val" : "Relation between a neuron and some structure its axon forms (chemical) synapses in.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
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          "val" : "David Osumi-Sutherland"
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          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
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          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
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      },
      "type" : "PROPERTY",
      "lbl" : "axon synapses in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002580",
      "type" : "PROPERTY",
      "lbl" : "logical macro assertion on an axiom"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002581",
      "meta" : {
        "definition" : {
          "val" : "If R <- P o Q is a defining property chain axiom, then it also holds that R -> P o Q. Note that this cannot be expressed directly in OWL",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "is a defining property chain axiom"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002340",
      "meta" : {
        "definition" : {
          "val" : "Holds between p and c when p is a transportation or localization process and the outcome of this process is to move c to a destination that is part of some s, where the start location of c is part of the region that surrounds s.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_ontology" ],
        "basicPropertyValues" : [ {
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          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "imports"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002582",
      "meta" : {
        "definition" : {
          "val" : "If R <- P o Q is a defining property chain axiom, then (1) R -> P o Q holds and (2) Q is either reflexive or locally reflexive. A corollary of this is that P SubPropertyOf R.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
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    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002338",
      "meta" : {
        "definition" : {
          "val" : "This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from some initial location l to some destination.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
        "basicPropertyValues" : [ {
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          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has target start location"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002339",
      "meta" : {
        "definition" : {
          "val" : "This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from a an initial location to some destination l.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has target end location"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002576",
      "meta" : {
        "definition" : {
          "val" : "inverse of has skeleton",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "skeleton of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002334",
      "meta" : {
        "definition" : {
          "val" : "inverse of regulates",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "regulated by (processual)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "regulated by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002335",
      "meta" : {
        "definition" : {
          "val" : "inverse of negatively regulates",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "negatively regulated by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002577",
      "meta" : {
        "definition" : {
          "val" : "A material entity consisting of multiple components that are causally integrated.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "May be replaced by a BFO class, as discussed in http://www.jbiomedsem.com/content/4/1/43"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.jbiomedsem.com/content/4/1/43"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "CLASS",
      "lbl" : "system"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002578",
      "meta" : {
        "definition" : {
          "val" : "Process(P1) directly regulates process(P2) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding  regulates the kinase activity (P2) of protein B then P1 directly regulates P2.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/RO_0002575",
          "val" : "http://purl.obolibrary.org/obo/RO_0002211"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "directly regulates (processual)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "directly regulates"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002336",
      "meta" : {
        "definition" : {
          "val" : "inverse of positively regulates",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "positively regulated by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002579",
      "meta" : {
        "definition" : {
          "val" : "relation p is the indirect form of relation q iff p is a subPropertyOf q, and there exists some p' such that p' is the direct form of q, p' o p' -> p, and forall x,y : x q y -> either (1) x p y or (2) x p' y",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/direct-and-indirect-relations/"
        }, {
          "pred" : "http://purl.org/dc/terms/creator",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is indirect form of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002337",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds via some process of localization",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is a grouping relation."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "related via localization to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002572",
      "meta" : {
        "definition" : {
          "val" : "s is luminal space of x iff s is lumen_of x and s is an immaterial entity",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "luminal space of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002330",
      "meta" : {
        "definition" : {
          "val" : "holds between two entities when some genome-level process such as gene expression is involved. This includes transcriptional, spliceosomal events. These relations can be used between either macromolecule entities (such as regions of nucleic acid) or between their abstract informational counterparts.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving the genome of an organism"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "genomically related to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0001000",
      "meta" : {
        "definition" : {
          "val" : "a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this nucleus derives from this parent nucleus (nuclear division)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "This is a very general relation. More specific relations are preferred when applicable, such as 'directly develops from'."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this cell derives from this parent cell (cell division)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "This relation is taken from the RO2005 version of RO. It may be obsoleted and replaced by relations with different definitions. See also the 'develops from' family of relations."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "derives_from"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "derives from"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002331",
      "meta" : {
        "definition" : {
          "val" : "c involved_in p if and only if c enables some process p', and p' is part of p",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "enables part of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "actively involved in"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://wiki.geneontology.org/index.php/Involved_in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "involved in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002573",
      "meta" : {
        "definition" : {
          "val" : "A relation that holds between an attribute or a qualifier and another attribute.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20064205"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "This relation is intended to be used in combination with PATO, to be able to refine PATO quality classes using modifiers such as 'abnormal' and 'normal'. It has yet to be formally aligned into an ontological framework; it's not clear what the ontological status of the \"modifiers\" are."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has modifier"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002574",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://dx.doi.org/10.1016/j.ecoinf.2014.08.005"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "participates in a biotic-biotic interaction with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002332",
      "meta" : {
        "definition" : {
          "val" : "p regulates levels of c if p regulates some amount (PATO:0000070) of c",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "every cellular sphingolipid homeostasis process regulates_level_of some sphingolipid"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "regulates levels of (process to entity)"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "regulates levels of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0001001",
      "meta" : {
        "definition" : {
          "val" : "a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this parent cell derives into this cell (cell division)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this parent nucleus derives into this nucleus (nuclear division)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "derives_into"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "This is a very general relation. More specific relations are preferred when applicable, such as 'directly develops into'. To avoid making statements about a future that may not come to pass, it is often better to use the backward-looking 'derives from' rather than the forward-looking 'derives into'."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "derives into"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002333",
      "meta" : {
        "definition" : {
          "val" : "inverse of enables",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_gocam" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "enabled by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002575",
      "meta" : {
        "definition" : {
          "val" : "relation p is the direct form of relation q iff p is a subPropertyOf q, p does not have the Transitive characteristic, q does have the Transitive characteristic, and for all x, y: x q y -> exists z1, z2, ..., zn such that x p z1 ... z2n y",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "The general property hierarchy is:\n\n  \"directly P\" SubPropertyOf \"P\"\n  Transitive(P)\n\nWhere we have an annotation assertion\n\n  \"directly P\" \"is direct form of\" \"P\""
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0002423",
          "val" : "If we have the annotation P is-direct-form-of Q, and we have inverses P' and Q', then it follows that P' is-direct-form-of Q'"
        }, {
          "pred" : "http://purl.org/dc/terms/creator",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/direct-and-indirect-relations/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is direct form of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0040042",
      "meta" : {
        "definition" : {
          "val" : "R is homemorphic for C iff (1) there exists some x,y such that x R y, and x and y instantiate C and (2) for all x, if x is an instance of C, and there exists some y some such that x R y, then it follows that y is an instance of C.",
          "xrefs" : [ ]
        },
        "comments" : [ "R homeomorphic-for C expands to: C SubClassOf R only C. Additionally, for any class D that is disjoint with C, we can also expand to C DisjointWith R some D, D DisjointWith R some C." ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2018-10-21T19:46:34Z"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://github.com/oborel/obo-relations/issues/164"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "part-of is homeomorphic for independent continuants."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is homeomorphic for"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002570",
      "meta" : {
        "definition" : {
          "val" : "x is a conduit for y iff y overlaps through the lumen_of of x, and y has parts on either side of the lumen of x.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "This relation holds between a thing with a 'conduit' (e.g. a bone foramen) and a 'conduee' (for example, a nerve) such that at the time the relationship holds, the conduee has two ends sticking out either end of the conduit. It should therefore note be used for objects that move through the conduit but whose spatial extent does not span the passage. For example, it would not be used for a mountain that contains a long tunnel through which trains pass. Nor would we use it for a digestive tract and objects such as food that pass through."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "UBERON:cjm"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "conduit for"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002571",
      "meta" : {
        "definition" : {
          "val" : "x lumen_of y iff x is the space or substance that is part of y and does not cross any of the inner membranes or boundaries of y that is maximal with respect to the volume of the convex hull.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "GOC:cjm"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "lumen of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002569",
      "meta" : {
        "definition" : {
          "val" : "inverse of branching part of",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco", "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has branching part"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002327",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "executes"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "catalyzes"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "a particular instances of akt-2 enables some instance of protein kinase activity"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is catalyzing"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "This relation is currently used experimentally by the Gene Ontology Consortium. It may not be stable and may be obsoleted at some future time."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is executing"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "enables"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002328",
      "meta" : {
        "definition" : {
          "val" : "A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "This is a grouping relation that collects relations used for the purpose of connecting structure and function"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "functionally related to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002329",
      "meta" : {
        "definition" : {
          "val" : "this relation holds between c and p when c is part of some c', and c' is capable of p.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "false"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "part of structure that is capable of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002323",
      "meta" : {
        "definition" : {
          "val" : "A mereological relationship or a topological relationship",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "mereotopologically related to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002565",
      "meta" : {
        "definition" : {
          "val" : "Holds between p and c when p is locomotion process and the outcome of this process is the change of location of c",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : ""
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "results in movement of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002566",
      "meta" : {
        "definition" : {
          "val" : "The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size).",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "causally influences (entity-centric)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Vasundra Touré"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "causally influences"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002324",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds between entities participating in some developmental process (GO:0032502)",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "developmentally related to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002567",
      "meta" : {
        "definition" : {
          "val" : "A relation that holds between elements of a musculoskeletal system or its analogs.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the biomechanical processes."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "biomechanically related to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002325",
      "meta" : {
        "definition" : {
          "val" : "a colocalizes_with b if and only if  a is transiently or peripherally associated with b[GO].",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.geneontology.org/GO.annotation.conventions.shtml#colocalizes_with"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "In the context of the Gene Ontology, colocalizes_with may be used for annotating to cellular component terms[GO]"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.org/dc/terms/creator",
          "val" : "Gene Ontology Consortium"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "Clp1p relocalizes from the nucleolus to the spindle and site of cell division; i.e. it is associated transiently with the spindle pole body and the contractile ring (evidence from GFP fusion). Clp1p colocalizes_with spindle pole body (GO:0005816) and contractile ring (GO:0005826)"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "colocalizes with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002326",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "We would like to say\n\nif and only if\n exists c', p'\n  c part_of c' and c' capable_of p\n   and\n  c capable_of p' and p' part_of p\nthen\n c contributes_to p\n\nHowever, this is not possible in OWL. We instead make this relation a sub-relation of the two chains, which gives us the inference in the one direction."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.geneontology.org/GO.annotation.conventions.shtml#contributes_to"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "Subunits of nuclear RNA polymerases: none of the individual subunits have RNA polymerase activity, yet all of these subunits contribute_to DNA-dependent RNA polymerase activity."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "In the context of the Gene Ontology, contributes_to may be used only with classes from the molecular function ontology. "
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "ATP citrate lyase (ACL) in Arabidopsis: it is a heterooctamer, composed of two types of subunits, ACLA and ACLB in a A(4)B(4) stoichiometry. Neither of the subunits expressed alone give ACL activity, but co-expression results in ACL activity. Both subunits contribute_to the ATP citrate lyase activity."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "eIF2: has three subunits (alpha, beta, gamma); one binds GTP; one binds RNA; the whole complex binds the ribosome (all three subunits are required for ribosome binding). So one subunit is annotated to GTP binding and one to RNA binding without qualifiers, and all three stand in the contributes_to relationship to \"ribosome binding\". And all three are part_of an eIF2 complex"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "contributes to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002568",
      "meta" : {
        "definition" : {
          "val" : "m1 has_muscle_antagonist m2 iff m1 has_muscle_insertion s, m2 has_muscle_insection s, m1 acts in opposition to m2, and m2 is responsible for returning the structure to its initial position.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "Wikipedia:Antagonist_(muscle)"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has muscle antagonist"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000232",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000122"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "curator note"
    }, {
      "id" : "http://www.w3.org/2000/01/rdf-schema#isDefinedBy",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "is defined by"
        } ]
      }
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0040035",
      "meta" : {
        "definition" : {
          "val" : "This relation groups  relations between diseases and any other kind of entity.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, in which the subject or object is a disease."
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2018-09-26T00:00:32Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "disease relationship"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002561",
      "meta" : {
        "definition" : {
          "val" : "If Rel is the relational form of a process Pr, then it follow that: Rel(x,y) <-> exists p : Pr(p), x partner-in p, y partner-in p",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/interaction-relations/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is symmetric relational form of process class"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002320",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds via some environmental process",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the process of evolution."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "evolutionarily related to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002562",
      "meta" : {
        "definition" : {
          "val" : "R is the relational form of a process if and only if either (1) R is the symmetric relational form of a process or (2) R is the asymmetric relational form of a process",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/interaction-relations/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is relational form of process class"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0040036",
      "meta" : {
        "definition" : {
          "val" : "p has anatomical participant c iff p has participant c, and c is an anatomical entity",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2018-09-26T01:08:58Z"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has anatomical participant"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002321",
      "meta" : {
        "definition" : {
          "val" : "A relationship that is mediated in some way by the environment or environmental feature (ENVO:00002297)",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Awaiting class for domain/range constraint, see: https://github.com/OBOFoundry/Experimental-OBO-Core/issues/6"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving ecological interactions"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "ecologically related to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002563",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://ontologydesignpatterns.org/wiki/Submissions:N-Ary_Relation_Pattern_%28OWL_2%29"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/interaction-relations/"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "interaction relation helper property"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002564",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "molecular interaction relation helper property"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002322",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "adapted for"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "An experimental relation currently used to connect a feature possessed by an organism (e.g. anatomical structure, biological process, phenotype or quality) to a habitat or environment in which that feature is well suited, adapted or provides a reproductive advantage for the organism. For example, fins to an aquatic environment. Usually this will mean that the structure is adapted for this environment, but we avoid saying this directly - primitive forms of the structure may not have evolved specifically for that environment (for example, early wings were not necessarily adapted for an aerial environment). Note also that this is a statement about the general class of structures - not every instance of a limb need confer an advantage for a terrestrial environment, e.g. if the limb is vestigial."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "confers advantage in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002560",
      "meta" : {
        "definition" : {
          "val" : "If Rel is the relational form of a process Pr, then it follow that: Rel(x,y) <-> exists p : Pr(p), x subject-partner-in p, y object-partner-in p",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/interaction-relations/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is asymmetric relational form of process class"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002558",
      "meta" : {
        "definition" : {
          "val" : "inverse of is evidence for",
          "xrefs" : [ ]
        },
        "comments" : [ "x has evidence y iff , x is  an information content entity, material entity or process, and y supports either the existence of x, or the truth value of x." ],
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259", "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/25052702"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has evidence"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002559",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "causally influenced by (entity-centric)"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "causally influenced by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002554",
      "meta" : {
        "definition" : {
          "val" : "inverse of hyperparasite of",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco", "http://purl.obolibrary.org/obo/RO_0002259" ],
        "synonyms" : [ {
          "pred" : "hasRelatedSynonym",
          "val" : "has epiparasite",
          "xrefs" : [ ]
        }, {
          "pred" : "hasRelatedSynonym",
          "val" : "has hyperparasite",
          "xrefs" : [ ]
        }, {
          "pred" : "hasRelatedSynonym",
          "val" : "hyperparasitoidized by",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "hyperparasitized by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002312",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "evolutionary variant of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002555",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://en.wikipedia.org/wiki/Allelopathy"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "x is an allelopath of y iff  xis an organism produces one or more biochemicals that influence the growth, survival, and reproduction of y"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://eol.org/schema/terms/allelopathyYes"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "allelopath of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002313",
      "meta" : {
        "definition" : {
          "val" : "Holds between p and c when p is a localization process (localization covers maintenance of localization as well as its establishment)  and the outcome of this process is to regulate the localization of c.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "regulates localization of"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "transports or maintains localization of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002314",
      "meta" : {
        "definition" : {
          "val" : "q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20064205"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/reflexivity/"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Because part_of is transitive, inheres in is a sub-relation of characteristic of part of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "inheres in part of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "characteristic of part of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002556",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "pathogen of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002315",
      "meta" : {
        "definition" : {
          "val" : "The relationship that links a specified entity with the process that results in an unspecified entity acquiring the features and characteristics of the specified entity",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension" ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
          "val" : "results_in_acquisition_of_features_of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "an annotation of gene X to cell differentiation with results_in_maturation_of CL:0000057 (fibroblast) means that at the end of the process the input cell that did not have features of a fibroblast, now has the features of a fibroblast."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "GOC:mtg_berkeley_2013"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "results in acquisition of features of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002557",
      "meta" : {
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has pathogen"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002550",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/temporal-durations/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "end, weeks post birth"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002551",
      "meta" : {
        "definition" : {
          "val" : "A relation between a segment or subdivision of an organism and the maximal subdivision of material entities that provides structural support for that segment or subdivision.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "Forelimb SubClassOf has_skeleton some 'Forelimb skeleton'"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has supporting framework"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "The skeleton of a structure may be a true skeleton (for example, the bony skeleton of a hand) or any kind of support framework (the hydrostatic skeleton of a sea star, the exoskeleton of an insect, the cytoskeleton of a cell)."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has skeleton"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002310",
      "meta" : {
        "definition" : {
          "val" : "A process occurring within or in the vicinity of an organism that exerts some causal influence on the organism via the interaction between an exposure stimulus and an exposure receptor. The exposure stimulus may be a process, material entity or condition (for example, lack of nutrients). The exposure receptor can be an organism, organism population or a part of an organism.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "This class is intended as a grouping for various domain and species-specific exposure classes. The ExO class http://purl.obolibrary.org/obo/ExO_0000002 'exposure event' assumes that all exposures involve stressors, which limits the applicability of this class to 'positive' exposures, e.g. exposing a plant to beneficial growing conditions."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "An exposure event in which a human is exposed to particulate matter in the air. Here the exposure stimulus/stress is the particulate matter, the receptor is the airways and lungs of the human,"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-06-05T17:55:39Z"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "An exposure event in which a plant is provided with fertilizer. The exposure receptor is the root system of the plant, the stimulus is the fertilizing chemical, the route is via the soil, possibly mediated by symbotic microbes."
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://github.com/oborel/obo-relations/pull/173"
        }, {
          "pred" : "http://purl.org/dc/terms/creator",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        } ]
      },
      "type" : "CLASS",
      "lbl" : "exposure event or process"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002552",
      "meta" : {
        "definition" : {
          "val" : "p results in the end of s if p results in a change of state in s whereby s either ceases to exist, or s becomes functionally impaired or s has its fate committed such that it is put on a path to be degraded.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "results in ending of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002553",
      "meta" : {
        "definition" : {
          "val" : "x is a hyperparasite of y iff x is a parasite of a parasite of the target organism y",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "synonyms" : [ {
          "pred" : "hasRelatedSynonym",
          "val" : "epiparasite of",
          "xrefs" : [ ]
        }, {
          "pred" : "hasNarrowSynonym",
          "val" : "hyperparasitoid of",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "https://en.wikipedia.org/wiki/Hyperparasite"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://eol.org/schema/terms/hyperparasitoidOf"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Note that parasite-of is a diret relationship, so hyperparasite-of is not considered a sub-relation, even though hyperparasitism can be considered a form of parasitism"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "hyperparasite of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002547",
      "meta" : {
        "definition" : {
          "val" : "Count of number of days intervening between the start of the stage and the time of coitum.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/temporal-durations/"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "For mouse staging: assuming that it takes place around midnight during a 7pm to 5am dark cycle (noon of the day on which the vaginal plug is found, the embryos are aged 0.5 days post coitum)"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "start, days post coitum"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002305",
      "meta" : {
        "comments" : [ "holds between x and y if and only if x is causally upstream of y and the progression of x decreases the frequency, rate or extent of y" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/RO_0004050",
          "val" : "http://purl.obolibrary.org/obo/RO_0002411"
        }, {
          "pred" : "http://purl.org/dc/terms/creator",
          "val" : "cjm"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "causally upstream of, negative effect"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002548",
      "meta" : {
        "definition" : {
          "val" : "Count of number of days intervening between the end of the stage and the time of coitum.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/temporal-durations/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "end, days post coitum"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002549",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/temporal-durations/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "start, weeks post birth"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002543",
      "meta" : {
        "definition" : {
          "val" : "Count of number of months intervening between the start of the stage and the time of birth according to a reference model. Note that the first month of post-birth development has the value of 0 for this property, and the period during which the child is one month old has the value 1.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/temporal-durations/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "start, months post birth"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002301",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "May be merged into parent relation"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "every mullerian duct regression (GO:0001880) results in regression of some mullerian duct (UBERON:0003890)"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "results in developmental regression of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002302",
      "meta" : {
        "definition" : {
          "val" : "Inverse of 'is substance that treats'",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/dc/terms/creator",
          "val" : "cjm"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is treated by substance"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002544",
      "meta" : {
        "definition" : {
          "val" : "Count of number of months intervening between the end of the stage and the time of birth according to a reference model. Note that the first month of post-birth development has the value of 1 for this property, and the period during which the child is one month old has the value 2",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/temporal-durations/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "end, months post birth"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002303",
      "meta" : {
        "definition" : {
          "val" : "x 'has habitat' y if and only if: x is an organism, y is a habitat, and y can sustain and allow the growth of a population of xs.",
          "xrefs" : [ ]
        },
        "comments" : [ "A population of xs will possess adaptations (either evolved naturally or via artifical selection) which permit it to exist and grow in y." ],
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "Hydrozoa (NCBITaxon_6074) SubClassOf 'has habitat' some 'Hydrozoa habitat'\nwhere\n'Hydrozoa habitat' SubClassOf overlaps some ('marine environment' (ENVO_00000569) and 'freshwater environment' (ENVO_01000306) and 'wetland' (ENVO_00000043)) and 'has part' some (freshwater (ENVO_00002011) or 'sea water' (ENVO_00002149)) -- http://eol.org/pages/1795/overview"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Pier Buttigieg"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "adapted for living in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has habitat"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002545",
      "meta" : {
        "definition" : {
          "val" : "Defines the start and end of a stage with a duration of 1 month, relative to either the time of fertilization or last menstrual period of the mother (to be clarified), counting from one, in terms of a reference model. Thus if month_of_gestation=3, then the stage is 2 month in.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/temporal-durations/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "month of gestation"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002304",
      "meta" : {
        "comments" : [ "holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y" ],
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/dc/terms/creator",
          "val" : "cjm"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0004049",
          "val" : "http://purl.obolibrary.org/obo/RO_0002411"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "causally upstream of, positive effect"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002546",
      "meta" : {
        "definition" : {
          "val" : "A relationship between a stage class and an anatomical structure or developmental process class, in which the stage is characterized by the appearance of the structure or the occurrence of the biological process",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/temporal-durations/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has developmental stage marker"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002309",
      "meta" : {
        "definition" : {
          "val" : "A relationship between an exposure event or process and any agent, stimulus, activity, or event that causally effects an organism and interacts with an exposure receptor during an exposure event.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/dc/terms/contributor",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2017-06-05T17:35:04Z"
        }, {
          "pred" : "http://purl.org/dc/terms/contributor",
          "val" : "Marie Angelique Laporte"
        }, {
          "pred" : "http://purl.org/dc/terms/contributor",
          "val" : "Austin Meier"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "cjm"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has exposure stimulus"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002540",
      "meta" : {
        "definition" : {
          "val" : "Count of number of days intervening between the end of the stage and the time of fertilization according to a reference model. Note that the first day of development has the value of 1 for this property.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/temporal-durations/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "end, days post fertilization"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002541",
      "meta" : {
        "definition" : {
          "val" : "Count of number of years intervening between the start of the stage and the time of birth according to a reference model. Note that the first year of post-birth development has the value of 0 for this property, and the period during which the child is one year old has the value 1.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/temporal-durations/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "start, years post birth"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002542",
      "meta" : {
        "definition" : {
          "val" : "Count of number of years intervening between the end of the stage and the time of birth according to a reference model. Note that the first year of post-birth development has the value of 1 for this property, and the period during which the child is one year old has the value 2",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/temporal-durations/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "end, years post birth"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002300",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
          "val" : "results_in_disappearance_of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "May be merged into parent relation"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "foramen ovale closure SubClassOf results in disappearance of foramen ovale"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "results in disappearance of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002536",
      "type" : "PROPERTY",
      "lbl" : "measurement property has unit"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002537",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/temporal-durations/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has start time value"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002538",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/temporal-durations/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has end time value"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002539",
      "meta" : {
        "definition" : {
          "val" : "Count of number of days intervening between the start of the stage and the time of fertilization according to a reference model. Note that the first day of development has the value of 0 for this property.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/temporal-durations/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "start, days post fertilization"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002532",
      "meta" : {
        "definition" : {
          "val" : "Any entity that is ordered in discrete units along a linear axis.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "CLASS",
      "lbl" : "sequentially ordered entity"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002533",
      "meta" : {
        "definition" : {
          "val" : "Any individual unit of a collection of like units arranged in a linear order",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "An individual unit can be a molecular entity such as a base pair, or an abstract entity, such as the abstraction of a base pair."
        } ]
      },
      "type" : "CLASS",
      "lbl" : "sequence atomic unit"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002534",
      "meta" : {
        "definition" : {
          "val" : "Any entity that can be divided into parts such that each part is an atomical unit of a sequence",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Sequence bearers can be molecular entities, such as a portion of a DNA molecule, or they can be abstract entities, such as an entity representing all human sonic hedgehog regions of the genome with a particular DNA sequence."
        } ]
      },
      "type" : "CLASS",
      "lbl" : "sequence bearer"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002535",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "This properties were created originally for the annotation of developmental or life cycle stages, such as for example Carnegie Stage 20 in humans. "
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "temporal logical macro assertion on a class"
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0003824",
      "type" : "CLASS",
      "lbl" : "catalytic activity"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000428",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "type" : "INDIVIDUAL",
      "lbl" : "requires discussion"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000426",
      "meta" : {
        "definition" : {
          "val" : "An assertion that holds between an OWL Object Property and a string or literal, where the value of the string or literal is a Common Logic sentence of collection of sentences that define the Object Property.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "first order logic expression"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002530",
      "meta" : {
        "definition" : {
          "val" : "x is immediately downstream of the sequence of y iff either (1) x and y have sequence units, and all units of x are downstream of all units of y, and x is sequentially adjacent to y, or (2) x and y are sequence units, in which case the immediately downstream relation is primitive and defined by context: for DNA bases, y would be adjacent and 5' to y",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/RO_0002575",
          "val" : "http://purl.obolibrary.org/obo/RO_0002529"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "A 3'UTR is immediately downstream of the sequence of the CDS from the same monocistronic transcript"
        }, {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://biorxiv.org/content/early/2014/06/27/006650.abstract"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is immediately downstream of sequence of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002531",
      "meta" : {
        "definition" : {
          "val" : "inverse of immediately downstream of",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://biorxiv.org/content/early/2014/06/27/006650.abstract"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "A 5'UTR is immediately upstream of the sequence of the CDS from the same monocistronic transcript"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is immediately upstream of sequence of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002525",
      "meta" : {
        "definition" : {
          "val" : "inverse of has subsequence",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "contained by"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://biorxiv.org/content/early/2014/06/27/006650.abstract"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is subsequence of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002526",
      "meta" : {
        "definition" : {
          "val" : "x overlaps the sequence of x if and only if x has a subsequence z and z is a subsequence of y.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://biorxiv.org/content/early/2014/06/27/006650.abstract"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "overlaps sequence of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002527",
      "meta" : {
        "definition" : {
          "val" : "x does not overlaps the sequence of x if and only if there is no z such that x has a subsequence z and z is a subsequence of y.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://biorxiv.org/content/early/2014/06/27/006650.abstract"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "disconnected from"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "does not overlap sequence of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002528",
      "meta" : {
        "definition" : {
          "val" : "inverse of downstream of sequence of",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://biorxiv.org/content/early/2014/06/27/006650.abstract"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is upstream of sequence of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002521",
      "meta" : {
        "definition" : {
          "val" : "x is sequentially aligned with if a significant portion bases of x and y correspond in terms of their base type and their relative ordering",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "Human Shh and Mouse Shh are sequentially aligned, by cirtue of the fact that they derive from the same ancestral sequence."
        }, {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://biorxiv.org/content/early/2014/06/27/006650.abstract"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is sequentially aligned with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002522",
      "meta" : {
        "definition" : {
          "val" : "x bounds the sequence of y iff the upstream-most part of x is upstream of or coincident with the upstream-most part of y, and the downstream-most part of x is downstream of or coincident with the downstream-most part of y",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "The genomic exons of a transcript bound the sequence of the genomic introns of the same transcript (but the introns are not subsequences of the exons)"
        }, {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://biorxiv.org/content/early/2014/06/27/006650.abstract"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "bounds sequence of"
    }, {
      "id" : "http://www.geneontology.org/formats/oboInOwl#inSubset",
      "type" : "PROPERTY",
      "lbl" : "in_subset"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002523",
      "meta" : {
        "definition" : {
          "val" : "inverse of bounds sequence of",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://biorxiv.org/content/early/2014/06/27/006650.abstract"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is bound by sequence of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002524",
      "meta" : {
        "definition" : {
          "val" : "x has subsequence y iff all of the sequence parts of x are sequence parts of y",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://biorxiv.org/content/early/2014/06/27/006650.abstract"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20226267"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "contains"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has subsequence"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002529",
      "meta" : {
        "definition" : {
          "val" : "x is downstream of the sequence of y iff either (1) x and y have sequence units, and all units of x are downstream of all units of y, or (2) x and y are sequence units, and x is either immediately downstream of y, or transitively downstream of y.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://biorxiv.org/content/early/2014/06/27/006650.abstract"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is downstream of sequence of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002520",
      "meta" : {
        "definition" : {
          "val" : "x is a consecutive sequence of y iff x has subsequence y, and all the parts of x are made of zero or more repetitions of y or sequences as the same type as y.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://biorxiv.org/content/early/2014/06/27/006650.abstract"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "In the SO paper, this was defined as an instance-type relation"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20226267"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is consecutive sequence of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002514",
      "meta" : {
        "definition" : {
          "val" : "A relation that holds between two entities that have the property of being sequences or having sequences. ",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20226267"
        }, {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://biorxiv.org/content/early/2014/06/27/006650.abstract"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving cause and effect."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "The domain and range of this relation include entities such as: information-bearing macromolecules such as DNA, or regions of these molecules; abstract information entities encoded as a linear sequence including text, abstract DNA sequences; Sequence features, entities that have a sequence or sequences. Note that these entities are not necessarily contiguous - for example, the mereological sum of exons on a genome of a particular gene."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "sequentially related to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002515",
      "meta" : {
        "definition" : {
          "val" : "x is sequentially adjacent to y iff x and y do not overlap and if there are no base units intervening between x and y",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "Every UTR is adjacent to a CDS of the same transcript"
        }, {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://biorxiv.org/content/early/2014/06/27/006650.abstract"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "Two consecutive DNA residues are sequentially adjacent"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20226267"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "Two exons on a processed transcript that were previously connected by an intron are adjacent"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "sequentially adjacent to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002516",
      "meta" : {
        "definition" : {
          "val" : "x has start sequence y if the start of x is identical to the start of y, and x has y as a subsequence",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "Every CDS has as a start sequence the start codon for that transcript"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "started by"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://biorxiv.org/content/early/2014/06/27/006650.abstract"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20226267"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has start sequence"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002517",
      "meta" : {
        "definition" : {
          "val" : "inverse of has start sequence",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20226267"
        }, {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://biorxiv.org/content/early/2014/06/27/006650.abstract"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "starts"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is start sequence of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002510",
      "meta" : {
        "definition" : {
          "val" : "x is transcribed from y if and only if x is synthesized from template y",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20226267"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "transcribed from"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002511",
      "meta" : {
        "definition" : {
          "val" : "inverse of transcribed from",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20226267"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "transcribed to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002512",
      "meta" : {
        "definition" : {
          "val" : "x is the ribosomal translation of y if and only if a ribosome reads x through a series of triplet codon-amino acid adaptor activities (GO:0030533) and produces y",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20226267"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "ribosomal translation of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "pg"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2020-09-22T11:05:29Z"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/subsets/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "valid_for_go_annotation_extension"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002513",
      "meta" : {
        "definition" : {
          "val" : "inverse of ribosomal translation of",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20226267"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "ribosomally translates to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002518",
      "meta" : {
        "definition" : {
          "val" : "x has end sequence y if the end of x is identical to the end of y, and x has y as a subsequence",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "Every CDS has as an end sequence the stop codon for that transcript (note this follows from the SO definition of CDS, in which stop codons are included)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "ended by"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20226267"
        }, {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://biorxiv.org/content/early/2014/06/27/006650.abstract"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has end sequence"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002519",
      "meta" : {
        "definition" : {
          "val" : "inverse of has end sequence",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "ends"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.org/spar/cito/citesAsAuthority",
          "val" : "http://biorxiv.org/content/early/2014/06/27/006650.abstract"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20226267"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is end sequence of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002503",
      "meta" : {
        "definition" : {
          "val" : "q towards e2 if and only if q is a relational quality such that q inheres-in some e, and e != e2 and q is dependent on e2",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20064205"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "This relation is provided in order to support the use of relational qualities such as 'concentration of'; for example, the concentration of C in V is a quality that inheres in V, but pertains to C."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "towards"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002504",
      "meta" : {
        "definition" : {
          "val" : "S always_present_in_taxon T if every fully formed member of taxon T has part some S, or is an instance of S",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "This is a very strong relation. Often we will not have enough evidence to know for sure that there are no species within a lineage that lack the structure - loss is common in evolution. However, there are some statements we can make with confidence - no vertebrate lineage could persist without a brain or a heart. All primates are limbed. "
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "never lost in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "forelimb always_present_in_taxon Euarchontoglires"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "brain always_present_in_taxon 'Vertebrata'"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "always present in taxon"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002505",
      "meta" : {
        "definition" : {
          "val" : "p has intermediate c if and only if p has parts p1, p2 and p1 has output c, and p2 has input c",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "'lysine biosynthetic process via diaminopimelate' SubClassOf has_intermediate some diaminopimelate"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has intermediate product"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has intermediate"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002506",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "The intent is that the process branch of the causal property hierarchy is primary (causal relations hold between occurrents/processes), and that the material branch is defined in terms of the process branch"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "causal relation between entities"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002500",
      "meta" : {
        "definition" : {
          "val" : "A relationship between a material entity and a process where the material entity has some causal role that influences the process",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "causal agent in process"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002501",
      "meta" : {
        "definition" : {
          "val" : "p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one of direct activation or direct inhibition. p may be upstream, downstream, part of or a container of q.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "causal relation between processes"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002502",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/BFO_0000169"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "depends on"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002507",
      "meta" : {
        "definition" : {
          "val" : "s determined by f if and only if s is a type of system, and f is a material entity that is part of s, such that f exerts a strong causal influence on the functioning of s, and the removal of f would cause the collapse of s.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "determined by (system to material entity)"
        }, {
          "pred" : "http://purl.org/dc/terms/creator",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://www.ncbi.nlm.nih.gov/pubmed/24330602"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "A coral reef environment is determined by a particular coral reef"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "The label for this relation is probably too general for its restricted use, where the domain is a system. It may be relabeled in future"
        }, {
          "pred" : "http://purl.org/dc/terms/creator",
          "val" : "Pier Buttigieg"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "determined by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002508",
      "meta" : {
        "definition" : {
          "val" : "inverse of determined by",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco", "http://purl.obolibrary.org/obo/RO_0002259" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
          "val" : "determines (material entity to system)"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "determines"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002509",
      "meta" : {
        "definition" : {
          "val" : "s 'determined by part of' w if and only if there exists some f such that (1) s 'determined by' f and (2) f part_of w, or f=w.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Chris Mungall"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "determined by part of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/CARO_0010000",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000412",
          "val" : "http://purl.obolibrary.org/obo/caro.owl"
        } ]
      },
      "type" : "CLASS",
      "lbl" : "multicellular anatomical structure"
    }, {
      "id" : "http://purl.obolibrary.org/obo/IAO_0000225",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        } ]
      },
      "lbl" : "obsolescence reason specification"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0009002",
      "meta" : {
        "definition" : {
          "val" : "\"has substance removed\" is a relation existing between two physical entities in which the first entity has had the second entity (a substance) removed from it at some point in time.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Damion Dooley"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "'egg white' 'has substance removed' some 'egg yolk'"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has substance removed"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0009001",
      "meta" : {
        "definition" : {
          "val" : "\"has substance added\" is a relation existing between a (physical) entity and a substance in which the entity has had the substance added to it at some point in time.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Damion Dooley"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "muffin 'has substance added' some 'baking soda'"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "The relation X 'has substance added' some Y doesn't imply that X still has Y in any detectable fashion subsequent to the addition. Water in dehydrated food or ice cubes are examples, as is food that undergoes chemical transformation. This definition should encompass recipe ingredients."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has substance added"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0009005",
      "meta" : {
        "definition" : {
          "val" : "'has primary substance added' indicates that an entity has had the given substance added to it in a proportion greater than any other added substance.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Damion Dooley"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "bread 'has primary substance added' some 'flour'"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has primary substance added"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0009004",
      "meta" : {
        "definition" : {
          "val" : "'has consumer' is a relation between a material entity and an organism in which the former can normally be digested or otherwise absorbed by the latter without immediate or persistent ill effect.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "sardine has consumer some homo sapiens"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Damion Dooley"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has consumer"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0009003",
      "meta" : {
        "definition" : {
          "val" : "\"immersed in\" is a relation between a (physical) entity and a fluid substance in which the entity is wholely or substantially surrounded by the substance.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "sardines 'immersed in' some 'oil and mustard'"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Damion Dooley"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "immersed in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002602",
      "meta" : {
        "definition" : {
          "val" : "A shortcut relationship between two entities x and y1, such that the intent is that the relationship is functional and inverse function, but there is no guarantee that this property holds.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "in approximate one to one relationship with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002603",
      "meta" : {
        "definition" : {
          "val" : "x is approximately equivalent to y if it is the case that x is equivalent, identical or near-equivalent to y",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "The precise meaning of this property is dependent upon some contexts. It is intended to group multiple possible formalisms. Possibilities include a probabilistic interpretation, for example, Pr(x=y) > 0.95. Other possibilities include reified statements of belief, for example, \"Database D states that x=y\""
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is approximately equivalent to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002604",
      "meta" : {
        "definition" : {
          "val" : "x is the opposite of y if there exists some distance metric M, and there exists no z such as M(x,z) <= M(x,y) or M(y,z) <= M(y,x).",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "'anterior end of organism' is-opposite-of 'posterior end of organism'"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "'increase in temperature' is-opposite-of 'decrease in temperature'"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is opposite of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/CL_0000000",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000412",
          "val" : "http://purl.obolibrary.org/obo/cl.owl"
        } ]
      },
      "type" : "CLASS",
      "lbl" : "cell"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002605",
      "meta" : {
        "definition" : {
          "val" : "x is indistinguishable from y if there exists some distance metric M, and there exists no z such as M(x,z) <= M(x,y) or M(y,z) <= M(y,x).",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "is indistinguishable from"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002600",
      "meta" : {
        "definition" : {
          "val" : "Holds between a material entity c and a pathological process p if and only if c is capable of some activity a, where a negatively regulates p.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "benzene -> cancer [CHEBI]"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "causes disease"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "capable of upregulating or causing pathological process"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002601",
      "meta" : {
        "definition" : {
          "val" : "A shortcut relationship that holds between two entities based on their identity criteria",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "logical macro assertion involving identity"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002606",
      "meta" : {
        "definition" : {
          "val" : "c is a substance that treats d if c is a material entity (such as a small molecule or compound) and d is a pathological process, phenotype or disease, and c is capable of some activity that negative regulates or decreases the magnitude of d.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://code.google.com/p/obo-relations/issues/detail?id=46"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "treats"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is substance that treats"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002607",
      "meta" : {
        "definition" : {
          "val" : "c is marker for d iff the presence or occurrence of d is correlated with the presence of occurrence of c, and the observation of c is used to infer the presence or occurrence of d. Note that this does not imply that c and d are in a direct causal relationship, as it may be the case that there is a third entity e that stands in a direct causal relationship with c and d.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "May be ceded to OBI"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "is marker for"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002608",
      "meta" : {
        "definition" : {
          "val" : "Inverse of 'causal agent in process'",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "process has causal agent"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002609",
      "meta" : {
        "definition" : {
          "val" : "A relationship that holds between two entities, where the relationship holds based on the presence or absence of statistical dependence relationship. The entities may be statistical variables, or they may be other kinds of entities such as diseases, chemical entities or processes.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
        } ],
        "deprecated" : true
      },
      "type" : "PROPERTY",
      "lbl" : "obsolete related via dependence to"
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0016879",
      "type" : "CLASS",
      "lbl" : "ligase activity, forming carbon-nitrogen bonds"
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0016874",
      "type" : "CLASS",
      "lbl" : "ligase activity"
    }, {
      "id" : "http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym",
      "type" : "PROPERTY",
      "lbl" : "has_related_synonym"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0011004",
      "meta" : {
        "definition" : {
          "val" : "The entity A is not immediately upstream of the entity B but A has an activity that regulates an activity performed by B.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Vasundra Touré"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "indirectly regulates activity of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0011002",
      "meta" : {
        "definition" : {
          "val" : "The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Vasundra Touré"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "regulates activity of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0011003",
      "meta" : {
        "definition" : {
          "val" : "The entity A has an activity that regulates the quantity or abundance or concentration of the entity B.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Vasundra  Touré"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "regulates quantity of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0011008",
      "meta" : {
        "definition" : {
          "val" : "The entity A has an activity that up-regulates by expression the quantity of B. The up-regulation is due to A having an effect on an intermediate entity (typically a DNA or mRNA element) which can produce B.\n\nFor example, protein A (transcription factor) indirectly increases by expression the quantity of protein B (gene product) if and only if A positively regulates the process of transcription or translation of a nucleic acid element that produces B.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Vasundra Touré"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "increases by expression quantity of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0011009",
      "meta" : {
        "definition" : {
          "val" : "The entity A has an activity that directly positively regulates the quantity of B.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Vasundra Touré"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "directly positively regulates quantity of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0004842",
      "type" : "CLASS",
      "lbl" : "ubiquitin-protein ligase activity"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0011007",
      "meta" : {
        "definition" : {
          "val" : "The entity A has an activity that down-regulates by repression the quantity of B. The down-regulation is due to A having an effect on an intermediate entity (typically a DNA or mRNA element) which can produce B.\n\nFor example, protein A (transcription factor) indirectly decreases by repression the quantity of protein B (gene product) if and only if A negatively regulates the process of transcription or translation of a nucleic acid element that produces B.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Vasundra Touré"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "decreases by repression quantity of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002801",
      "meta" : {
        "definition" : {
          "val" : "Two or more individuals sharing the same roost site (cave, mine, tree or tree hollow, animal burrow, leaf tent, rock crack, space in man-made structure, etc.). Individuals that are sharing a communal roost may be said to be co-roosting. The roost may be either a day roost where the individuals rest during daytime hours, or a night roost where individuals roost to feed, groom, or rest in between flights and/or foraging bouts.  Communal roosting as thus defined is an umbrella term within which different specialized types -- which are not mutually exclusive -- may be recognized based on taxonomy and the temporal and spatial relationships of the individuals that are co-roosting.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "https://en.wikipedia.org/wiki/Communal_roosting"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "co-roosts with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0011010",
      "meta" : {
        "definition" : {
          "val" : "The entity A has an activity that directly negatively regulates the quantity of B.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Vasundra Touré"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "directly negatively regulates quantity of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0011015",
      "meta" : {
        "definition" : {
          "val" : "An entity A physically interacts with B and A has an activity that increases the amount of an entity B by stabilizing it.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "AKT1 stabilizes quantity of XIAP (interaction from Signor database: SIGNOR-119488)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Vasundra Touré"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "stabilizes quantity of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0011016",
      "meta" : {
        "definition" : {
          "val" : "The entity A is not immediately upstream of the entity B and has an activity that down-regulates an activity performed by B.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "indirectly inhibits"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Vasundra Touré"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "indirectly negatively regulates activity of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0011013",
      "meta" : {
        "definition" : {
          "val" : "The entity A is not immediately upstream of the entity B and has an activity that up-regulates an activity performed by B.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "indirectly activates"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Vasundra Touré"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "indirectly positively regulates activity of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0011014",
      "meta" : {
        "definition" : {
          "val" : "An entity A directly interacts with B and A has an activity that decreases the amount of an entity B by degradating it.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "AKT1 destabilizes quantity of FOXO (interaction from Signor database: SIGNOR-252844)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Vasundra Touré"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "destabilizes quantity of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0042734",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000412",
          "val" : "http://purl.obolibrary.org/obo/go.owl"
        } ]
      },
      "type" : "CLASS",
      "lbl" : "presynaptic membrane"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0011022",
      "meta" : {
        "definition" : {
          "val" : "The entity A is not immediately upstream of the entity B, but A has an activity that regulates the quantity or abundance or concentration of B.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Vasundra Touré"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "indirectly regulates quantity of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0011023",
      "meta" : {
        "definition" : {
          "val" : "The entity A does not physically interact with the entity B, and A has an activity that down-regulates the quantity or abundance or concentration of B.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Vasundra Touré"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "indirectly negatively regulates quantity of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0011021",
      "meta" : {
        "definition" : {
          "val" : "The entity A, immediately upstream of B, has an activity that directly regulates the quantity of B.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Vasundra Touré"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "directly regulates quantity of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0011024",
      "meta" : {
        "definition" : {
          "val" : "The entity A does not physically interact with the entity B, and A has an activity that up-regulates the quantity or abundance or concentration of B.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Vasundra Touré"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "indirectly positively regulates quantity of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/CARO_0030000",
      "type" : "CLASS",
      "lbl" : "biological entity"
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0042995",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000412",
          "val" : "http://purl.obolibrary.org/obo/go.owl"
        } ]
      },
      "type" : "CLASS",
      "lbl" : "cell projection"
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000050",
      "meta" : {
        "definition" : {
          "val" : "a core relation that holds between a part and its whole",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "part_of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
          "val" : "http://purl.obolibrary.org/obo/BFO_0000004"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
          "val" : "http://purl.obolibrary.org/obo/BFO_0000003"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
          "val" : "http://purl.obolibrary.org/obo/BFO_0000002"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://www.obofoundry.org/ro/#OBO_REL:part_of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "my brain is part of my body (continuant parthood, two material entities)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
          "val" : "http://purl.obolibrary.org/obo/BFO_0000020"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://ontologydesignpatterns.org/wiki/Community:Parts_and_Collections"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
          "val" : "http://purl.obolibrary.org/obo/BFO_0000017"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
          "val" : "http://purl.obolibrary.org/obo/BFO_0000019"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.)\n\nA continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "is part of"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this day is part of this year (occurrent parthood)"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://ontologydesignpatterns.org/wiki/Submissions:PartOf"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
          "val" : "http://purl.obolibrary.org/obo/BFO_0000031"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "part of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000055",
      "meta" : {
        "comments" : [ "Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this disease course realizes this disease"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this investigation realizes this investigator role"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "realizes"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000600",
          "val" : "to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this shattering realizes this fragility"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#isDefinedBy",
          "val" : "http://purl.obolibrary.org/obo/iao.owl"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "realizes"
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000051",
      "meta" : {
        "definition" : {
          "val" : "a core relation that holds between a whole and its part",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "has_part"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.)\n\nA continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "has part"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this year has part this day (occurrent parthood)"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "my body has part my brain (continuant parthood, two material entities)"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has part"
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000054",
      "meta" : {
        "comments" : [ "Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#isDefinedBy",
          "val" : "http://purl.obolibrary.org/obo/bfo.owl"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "realized_in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this disease is realized in this disease course"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this fragility is realized in this shattering"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is realized by"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
          "val" : "this investigator role is realized in this investigation"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "realized in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000600",
          "val" : "[copied from inverse property 'realizes'] to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "realized in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0001900",
      "meta" : {
        "definition" : {
          "val" : "An assertion that holds between an OWL Object Property and a temporal interpretation that elucidates how OWL Class Axioms that use this property are to be interpreted in a temporal context.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "https://oborel.github.io/obo-relations/temporal-semantics/"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "temporal interpretation"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0001901",
      "meta" : {
        "definition" : {
          "val" : "\n\n## Elucidation\n\nThis is used when the statement/axiom is assumed to hold true 'eternally'\n\n## How to interpret (informal)\n\nFirst the \"atemporal\" FOL is derived from the OWL using the standard\ninterpretation. This axiom is temporalized by embedding the axiom\nwithin a for-all-times quantified sentence. The t argument is added to\nall instantiation predicates and predicates that use this relation.\n\n## Example\n\n    Class: nucleus\n    SubClassOf: part_of some cell\n\n    forall t :\n      forall n :\n        instance_of(n,Nucleus,t)\n         implies\n        exists c :\n          instance_of(c,Cell,t)\n          part_of(n,c,t)\n\n## Notes\n\nThis interpretation is *not* the same as an at-all-times relation\n\n",
          "xrefs" : [ ]
        }
      },
      "type" : "INDIVIDUAL",
      "lbl" : "axiom holds for all times"
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000040",
      "meta" : {
        "definition" : {
          "val" : "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.",
          "xrefs" : [ ]
        }
      },
      "type" : "CLASS",
      "lbl" : "material entity"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0013003",
      "meta" : {
        "definition" : {
          "val" : "A relationship between a neuron and a region, where the neuron has a functionally relevant number of output synapses in that region.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2020-07-17T09:45:06Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "http://orcid.org/0000-0002-1373-1705"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "sends synaptic output to region"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0001902",
      "meta" : {
        "definition" : {
          "val" : "\n\n## Elucidation\n\nThis is used when the first-order logic form of the relation is\nbinary, and takes no temporal argument.\n\n## Example:\n\n    Class: limb\n    SubClassOf: develops_from some lateral-plate-mesoderm\n\n     forall t, t2:\n      forall x :\n        instance_of(x,Limb,t)\n         implies\n        exists y :\n          instance_of(y,LPM,t2)\n          develops_from(x,y)\n\n\n",
          "xrefs" : [ ]
        }
      },
      "type" : "INDIVIDUAL",
      "lbl" : "relation has no temporal argument"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0013002",
      "meta" : {
        "definition" : {
          "val" : "A relationship between a neuron and a region, where the neuron has a functionally relevant number of input synapses in that region.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2020-07-17T09:42:23Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "http://orcid.org/0000-0002-1373-1705"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "receives synaptic input in region"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0013001",
      "meta" : {
        "definition" : {
          "val" : "A relationship between a neuron and a region, where the neuron has a functionally relevant number of input and/or output synapses in that region.",
          "xrefs" : [ ]
        },
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "has synaptic input or output in",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "http://orcid.org/0000-0002-1373-1705"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2020-07-17T09:26:52Z"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has synaptic IO in region"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0013007",
      "meta" : {
        "definition" : {
          "val" : "Relation between a sensory neuron and some structure in which it receives sensory input via a sensory dendrite.",
          "xrefs" : [ ]
        },
        "synonyms" : [ {
          "pred" : "hasExactSynonym",
          "val" : "has sensory terminal in",
          "xrefs" : [ ]
        }, {
          "pred" : "hasExactSynonym",
          "val" : "has sensory dendrite location",
          "xrefs" : [ ]
        }, {
          "pred" : "hasExactSynonym",
          "val" : "has sensory terminal location",
          "xrefs" : [ ]
        } ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2020-07-20T12:10:09Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "http://orcid.org/0000-0002-1373-1705"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has sensory dendrite in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0013006",
      "meta" : {
        "definition" : {
          "val" : "A relationship between a neuron and a region, where the neuron has a functionally relevant number output synapses distributed throughout that region (rather than confined to a subregion).",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "http://orcid.org/0000-0002-1373-1705"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2020-07-17T09:57:27Z"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "sends synaptic output throughout"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0013005",
      "meta" : {
        "definition" : {
          "val" : "A relationship between a neuron and a region, where the neuron has a functionally relevant number of input synapses distributed throughout that region (rather than confined to a subregion).",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2020-07-17T09:55:36Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "http://orcid.org/0000-0002-1373-1705"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "receives synaptic input throughout"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0013004",
      "meta" : {
        "definition" : {
          "val" : "A relationship between a neuron and a region, where the neuron has a functionally relevant number of input and/or output synapses distributed throughout that region (rather than confined to a subregion).",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2020-07-17T09:52:19Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "http://orcid.org/0000-0002-1373-1705"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has synaptic IO throughout"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0013009",
      "meta" : {
        "definition" : {
          "val" : "A relationship between a neuron and a cell that it has a functionally relevant number of chemical synapses to.",
          "xrefs" : [ ]
        },
        "comments" : [ "Not restricting range to 'cell' - object may be a muscle containing a cell targeted by the neuron." ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2021-05-26T08:41:07Z"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "http://orcid.org/0000-0002-1373-1705"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "sends synaptic output to cell"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0013008",
      "meta" : {
        "definition" : {
          "val" : "A relationship between an anatomical structure (including cells) and a neuron that has a functionally relevant number of chemical synapses to it.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
          "val" : "http://orcid.org/0000-0002-1373-1705"
        }, {
          "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
          "val" : "2021-05-26T08:40:18Z"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "receives synaptic input from neuron"
    }, {
      "id" : "http://purl.obolibrary.org/obo/PATO_0001199",
      "type" : "CLASS",
      "lbl" : "linear"
    }, {
      "id" : "http://purl.obolibrary.org/obo/UPHENO_0001001",
      "type" : "CLASS",
      "lbl" : "phenotype"
    }, {
      "id" : "http://purl.obolibrary.org/obo/OGMS_0000031",
      "meta" : {
        "definition" : {
          "val" : "A disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism.",
          "xrefs" : [ ]
        }
      },
      "type" : "CLASS",
      "lbl" : "disease"
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000060",
      "meta" : {
        "comments" : [ "accidentally included in BFO 1.2 proposal\n        - should have been BFO_0000062" ],
        "deprecated" : true
      },
      "type" : "PROPERTY",
      "lbl" : "obsolete preceded by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000066",
      "meta" : {
        "definition" : {
          "val" : "b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t",
          "xrefs" : [ ]
        },
        "comments" : [ "Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant" ],
        "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_ontology" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "occurs_in"
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#isDefinedBy",
          "val" : "http://purl.obolibrary.org/obo/bfo.owl"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "unfolds in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "occurs in"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "unfolds_in"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "occurs in"
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000067",
      "meta" : {
        "definition" : {
          "val" : "[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t",
          "xrefs" : [ ]
        },
        "comments" : [ "Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant" ],
        "basicPropertyValues" : [ {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#isDefinedBy",
          "val" : "http://purl.obolibrary.org/obo/bfo.owl"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "site of"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "contains process"
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000062",
      "meta" : {
        "definition" : {
          "val" : "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.org/dc/elements/1.1/source",
          "val" : "http://www.obofoundry.org/ro/#OBO_REL:preceded_by"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C.    The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "is preceded by"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "preceded by"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
          "val" : "preceded_by"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "preceded by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000063",
      "meta" : {
        "definition" : {
          "val" : "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
          "val" : "precedes"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "precedes"
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000019",
      "type" : "CLASS",
      "lbl" : "quality"
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000015",
      "meta" : {
        "definition" : {
          "val" : "An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.",
          "xrefs" : [ ]
        }
      },
      "type" : "CLASS",
      "lbl" : "process"
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000016",
      "type" : "CLASS",
      "lbl" : "disposition"
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000017",
      "meta" : {
        "definition" : {
          "val" : "A specifically dependent continuant  that inheres in continuant  entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances.",
          "xrefs" : [ ]
        }
      },
      "type" : "CLASS",
      "lbl" : "realizable entity"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0008508",
      "meta" : {
        "definition" : {
          "val" : "inverse of lays eggs on",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "has eggs laid on by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0008507",
      "meta" : {
        "definition" : {
          "val" : "An interaction relationship in which organism a lays eggs on the outside surface of organism b. Organism b is neither helped nor harmed in the process of egg laying or incubation.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "lays eggs on"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0008506",
      "meta" : {
        "definition" : {
          "val" : "An interaction relationship describing organisms that often occur together at the same time and space or in the same environment.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "ecologically co-occurs with"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0008505",
      "meta" : {
        "definition" : {
          "val" : "An interaction relationship wherein one organism creates a structure or environment that is lived in by another organism.",
          "xrefs" : [ ]
        }
      },
      "type" : "PROPERTY",
      "lbl" : "creates habitat for"
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000004",
      "meta" : {
        "definition" : {
          "val" : "A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.",
          "xrefs" : [ ]
        }
      },
      "type" : "CLASS",
      "lbl" : "independent continuant"
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000006",
      "type" : "CLASS",
      "lbl" : "spatial region"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0008504",
      "meta" : {
        "definition" : {
          "val" : "inverse of kleptoparasite of",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ]
      },
      "type" : "PROPERTY",
      "lbl" : "kleptoparasitized by"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0008503",
      "meta" : {
        "definition" : {
          "val" : "A sub-relation of parasite of in which a parasite steals resources from another organism, usually food or nest material",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "https://en.wikipedia.org/wiki/Kleptoparasitism"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "kleptoparasite of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0008502",
      "meta" : {
        "definition" : {
          "val" : "inverse of epiphyte of",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ]
      },
      "type" : "PROPERTY",
      "lbl" : "has epiphyte"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0008501",
      "meta" : {
        "definition" : {
          "val" : "An interaction relationship wherein a plant or algae is living on the outside surface of another plant.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
          "val" : "https://en.wikipedia.org/wiki/Epiphyte"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "epiphyte of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/PATO_0000051",
      "type" : "CLASS",
      "lbl" : "morphology"
    }, {
      "id" : "http://purl.obolibrary.org/obo/PATO_0000052",
      "type" : "CLASS",
      "lbl" : "shape"
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000002",
      "meta" : {
        "definition" : {
          "val" : "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.",
          "xrefs" : [ ]
        }
      },
      "type" : "CLASS",
      "lbl" : "continuant"
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000003",
      "meta" : {
        "definition" : {
          "val" : "An entity that has temporal parts and that happens, unfolds or develops through time.",
          "xrefs" : [ ]
        }
      },
      "type" : "CLASS",
      "lbl" : "occurrent"
    }, {
      "id" : "http://www.geneontology.org/formats/oboInOwl#hasExactSynonym",
      "type" : "PROPERTY",
      "lbl" : "has_exact_synonym"
    }, {
      "id" : "http://purl.obolibrary.org/obo/PATO_0002009",
      "type" : "CLASS",
      "lbl" : "branchiness"
    }, {
      "id" : "http://purl.obolibrary.org/obo/GO_0016881",
      "type" : "CLASS",
      "lbl" : "acid-amino acid ligase activity"
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000034",
      "type" : "CLASS",
      "lbl" : "function"
    }, {
      "id" : "http://purl.obolibrary.org/obo/ENVO_01000254",
      "type" : "CLASS",
      "lbl" : "environmental system"
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000031",
      "meta" : {
        "definition" : {
          "val" : "A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time.",
          "xrefs" : [ ]
        }
      },
      "type" : "CLASS",
      "lbl" : "generically dependent continuant"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0002180",
      "meta" : {
        "definition" : {
          "val" : "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.",
          "xrefs" : [ ]
        },
        "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
          "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
          "val" : "http://purl.obolibrary.org/obo/RO_0001901"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit."
        }, {
          "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
          "val" : "http://ontologydesignpatterns.org/wiki/Submissions:Componency"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "has component"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0015002",
      "meta" : {
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Patrick Ray"
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "exemplar data of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0015003",
      "meta" : {
        "definition" : {
          "val" : "A relation between a group and another group it is part of but does not fully constitute.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Shawn Tan"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
          "val" : "This is used specifically for sets whose members are specified by some set-forming operator (method of grouping) such as clustering analyses in single cell transcriptomics."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "X subcluster_of Y iff: X and Y are clusters/groups; X != Y; all members of X are also members of Y."
        } ]
      },
      "type" : "PROPERTY",
      "lbl" : "subcluster of"
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000023",
      "meta" : {
        "definition" : {
          "val" : "A realizable entity  the manifestation of which brings about some result or end that is not essential to a continuant  in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant  in some kinds of natural, social or institutional contexts.",
          "xrefs" : [ ]
        }
      },
      "type" : "CLASS",
      "lbl" : "role"
    }, {
      "id" : "http://www.geneontology.org/formats/oboInOwl#SubsetProperty",
      "type" : "PROPERTY",
      "lbl" : "subset_property"
    }, {
      "id" : "http://purl.obolibrary.org/obo/BFO_0000020",
      "meta" : {
        "definition" : {
          "val" : "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.",
          "xrefs" : [ ]
        }
      },
      "type" : "CLASS",
      "lbl" : "specifically dependent continuant"
    }, {
      "id" : "http://purl.obolibrary.org/obo/RO_0015001",
      "meta" : {
        "definition" : {
          "val" : "A relation between a material entity and some data in which the data is taken as exemplifying the material entity.",
          "xrefs" : [ ]
        },
        "basicPropertyValues" : [ {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
          "val" : "C has_exemplar_data y iff x is an instance of C and y is data about x that is taken as exemplifying of C."
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
          "val" : "Patrick Ray"
        }, {
          "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
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