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DESCRIPTION
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Package: pksensi
Title: Global Sensitivity Analysis in Physiologically Based Kinetic Modeling
Version: 1.4.0.9000
Authors@R: c(
person(given = "Nan-Hung",
family = "Hsieh",
role = c("aut", "cre"),
email = "d99622005@ntu.edu.tw",
comment = c(ORCID = "0000-0003-0163-2766")),
person(given = "Brad",
family = "Reisfeld",
role = "ctb",
comment = c(ORCID = "0000-0003-1310-1495")),
person(given = "Weihsueh A.",
family = "Chiu",
role = "ctb",
comment = c(ORCID = "0000-0002-7575-2368")))
Description: Applying the global sensitivity analysis workflow to investigate
the parameter uncertainty and sensitivity in physiologically based
kinetic (PK) models, especially the physiologically based
pharmacokinetic/toxicokinetic model with multivariate outputs.
The package also provides some functions to check the convergence
and sensitivity of model parameters. The workflow was first mentioned
in Hsieh et al., (2018) <doi:10.3389/fphar.2018.00588>, then further
refined (Hsieh et al., 2020 <doi:10.1016/j.softx.2020.100609>).
License: GPL-3 | file LICENSE
URL: https://github.com/nanhung/pksensi,
https://nanhung.github.io/pksensi/
BugReports: https://github.com/nanhung/pksensi/issues
Depends:
R (>= 4.1)
Imports:
ggplot2,
data.table,
deSolve,
foreach,
parallel,
doParallel
Suggests:
covr,
knitr,
httk,
rmarkdown,
testthat
VignetteBuilder:
knitr
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.3.2
Language: en-US
Roxygen: list(markdown = TRUE)