How to model relations between UniProt, EC, Rhea, and GO?

[cthoyt]

As suggested by Chris in biopragmatics/pyobo#168 (comment), I am bringing this to the RO issue tracker. I want to use well-defined RO properties to model the relationships between reactions in Rhea, molecular functions in GO, and gene products in EC so I can fill out all of the blanks in the following diagram. Further, we know of a protein that 1) has the molecular function, 2) catalyzes the reaction, 3) is an instance of the enzyme class in this diagram, so I also want to figure out the right way to annotate those.

Can RO do the following:

1. Let me know what relations exist that are appropriate for this
2. Help me mint new relations with appropriate semantics to cover the remaining

[JervenBolleman]

From Rhea to EC: there is an existing IRI that you can use. This captures the exact semantics of the relationships to the detail that can be recovered at this time.

For UniProt to Rhea: if you wish to use a class formalism this would not be a direct link. It would be something like

uniprot:Q93NH4 a owl:Class, rdfs:subClassOf up:Protein .

uniprot:Q93NH4#rhea-11800 rdfs:subClassOf  uniprot:Q93NH4 ;
  rdf:subClassOf [
     a owl:Restriction ;
     owl:onProperty up:catalyticActivity ;
     owl:someValuesFrom rhea:11800 .
  ], ec:1.5.3.5 .

But that is just my first inspiration.