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Hi, it might help to run some benchmarks with and without threads recording run time, CPU, memory and I/O. This provides context to "increased to 60G" (ie how much ram it used before)
--threads INT
Use multithreading with INT worker threads. The option is currently used only for the compression of the output stream, only when --output-type is b or z. Default: 0.
bcftools merge ---file-list list.txt -O z -o output.vcf --threads 16
Why the CPU% is only about 130%, but Virtual Memory has increased to 60G?
What‘s important is that the MERGE speed has not been increased!!!
(My file-list contains 200 samples with vcf.gz format. There are infomation of each site in those VCF files, not only variants site)
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