TableModel().validate() intentionally skips check for unique instance_key values (grouped by region_key values)

[LucaMarconato]

The check of unique instance_key values (after grouping them by region_key values) is an expensive check, therefore it is performed only during table parsing and not validation.

Anyway, we should add a flag to validate() to allowing performing this check, and do this when writing.

We need to modify the tests for checking for this (something like uncommenting the code here below).

    @pytest.mark.parametrize("model", [TableModel])
    @pytest.mark.parametrize("region", [["sample_1"] * 5 + ["sample_2"] * 5])
    def test_table_instance_key_values_not_unique(self, model: TableModel, region: str | np.ndarray):
        region_key = "region"
        obs = pd.DataFrame(RNG.integers(0, 100, size=(10, 3)), columns=["A", "B", "C"])
        obs[region_key] = region
        obs["A"] = [1] * 5 + list(range(5))
        adata = AnnData(RNG.normal(size=(10, 2)), obs=obs)

        # check parse fails
        with pytest.raises(ValueError, match=re.escape("Instance key column for region(s) `sample_1`")):
            model.parse(adata, region=region, region_key=region_key, instance_key="A")
        # # check also validate fails
        # adata.uns[TableModel.ATTRS_KEY] = {
        #     TableModel.REGION_KEY: region,
        #     TableModel.REGION_KEY_KEY: region_key,
        #     TableModel.INSTANCE_KEY: "A",
        # }
        # with pytest.raises(ValueError, match=re.escape("Instance key column for region(s) `sample_1`")):
        #     model().validate(adata)
        # del adata.uns[TableModel.ATTRS_KEY]

        adata.obs["A"] = [1] * 10

        # check parse fails
        with pytest.raises(ValueError, match=re.escape("Instance key column for region(s) `sample_1, sample_2`")):
            model.parse(adata, region=region, region_key=region_key, instance_key="A")
        # # check also validate fails
        # adata.uns[TableModel.ATTRS_KEY] = {
        #     TableModel.REGION_KEY: region,
        #     TableModel.REGION_KEY_KEY: region_key,
        #     TableModel.INSTANCE_KEY: "A",
        # }
        # with pytest.raises(ValueError, match=re.escape("Instance key column for region(s) `sample_1, sample_2`")):
        #     model().validate(adata)
        # del adata.uns[TableModel.ATTRS_KEY]