combined2.csv

nct_id,overall_status,start_date,completion_date,condition,Study design info,eligibility,has_expanded_access,enrollment
NCT04453566,Recruiting,"May 27, 2020",December 2020,"COVID-19,Life Satisfaction,Anxiety,Mental Health Wellness 1,Athlete,Stress","Other,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:35 Years",No,120
NCT04403386,Recruiting,"June 1, 2020","May 31, 2022",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:30 Years,Max Age:55 Years",No,200
NCT04526977,Not yet recruiting,"September 1, 2020","September 30, 2021","Covid19,Immune Suppression,HIV-1-infection","Case-Control,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:85 Years",No,90
NCT04561102,Enrolling by invitation,"September 11, 2020","December 31, 2020",SARS-CoV-2,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2500
NCT04375735,Not yet recruiting,"July 1, 2020","July 1, 2021","ARDS, Human,COVID-19","Randomized,Parallel Assignment,Patients will be randomly assigned to either receive exogenous surfactant daily for 3 days, or receive standard treatment.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04320472,Recruiting,"March 23, 2020",December 2020,"COVID-19,Encephalopathy,Critically Ill","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,250
NCT04508023,Recruiting,"August 13, 2020","April 6, 2021",Coronavirus Disease 2019 (COVID-19),"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,4000
NCT04460027,Recruiting,"June 22, 2020","August 31, 2020","Substance Use Disorders,Alcohol Use Disorder","Randomized,Parallel Assignment,Treatment,Double (Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:65 Years",No,160
NCT04349540,"Active, not recruiting","April 15, 2020","January 15, 2021",COVID19,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:3 Months,Max Age:N/A",No,40
NCT04323527,Completed,"March 23, 2020","June 7, 2020","SARS-CoV Infection,Severe Acute Respiratory Syndrome (SARS) Pneumonia","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,278
NCT04506528,Recruiting,"August 10, 2020","December 31, 2021","Covid19,Cancer,Nicotine Dependence,Pulmonary Disease,Cardiovascular Diseases,Immunosuppression Disorders","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,170000
NCT04568525,Completed,"July 1, 2020","August 1, 2020",Covid19,"Randomized,Parallel Assignment,Randomized clinical trials,Diagnostic,Single (Participant)","gender:All,Min Age:18 Years,Max Age:75 Years",No,195
NCT04407507,Not yet recruiting,June 2020,October 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,Single (Care Provider)","gender:All,Min Age:18 Years,Max Age:N/A",No,66
NCT04517136,Recruiting,"September 14, 2020","February 14, 2021","Covid19,SARS-CoV Infection,Burnout, Caregiver,Burnout, Professional","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:60 Years",No,60
NCT04361019,Recruiting,"April 16, 2020","October 20, 2020",Physical Activity,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,25000
NCT04385251,Recruiting,"June 18, 2020","June 30, 2021","COVID,COVID19,SARS-CoV 2,Dyspnea","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,10000
NCT04339816,Recruiting,"May 13, 2020","June 30, 2022","COVID-19,Respiratory Failure","Randomized,Parallel Assignment,Prospective, multi-centre, randomised, pragmatic, double blind trial,Treatment,Triple (Participant, Care Provider, Outcomes Assessor),Visually unrecognisable IP or placebo will be prepared by dedicated unblinded study pharmacist and handed over to care provider immediately before administration","gender:All,Min Age:18 Years,Max Age:N/A",No,240
NCT04344756,Not yet recruiting,"April 20, 2020","September 30, 2020",COVID19 Pneumonia,"Randomized,Parallel Assignment,Randomized clinical trial with 2 parallels arms, 1:1, stratified on disease severity (ventilation or not),Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,808
NCT04377997,Not yet recruiting,"May 15, 2020","January 1, 2022","Cardiovascular Diseases,COVID-19","Randomized,Parallel Assignment,randomized 1:1,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04391127,"Active, not recruiting","May 4, 2020","September 30, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Care Provider),Two non-transparent bottles The first bottle will contain the initial treatment: Two ivermectin tablets, two hydroxychloroquine tablets, or two placebo tablets.
The second bottle will contain the follow-up treatment (10 tablets): Two tablets will be indicated, which will be take 12 hours after ingestion of the initial bottle and then one tablet every 12 hours for 4 more days. This bottle will contain placebo and hydroxychloroquine according to the corresponding group.","gender:All,Min Age:16 Years,Max Age:90 Years",No,108
NCT04324190,Recruiting,"April 8, 2020",December 2021,"COVID-19,Psychosocial Stress,Mental Health","Randomized,Sequential Assignment,Randomized controlled trial with a waiting comparator condition (provision of WHO recommendations, comparable to treatment as usual, TAU), consisting of a two weeks waiting period during which general WHO recommendations how to handle stress in the context of the COVID-19 pandemic will be provided. All subjects in the waiting condition will undergo the intervention following the waiting period. Main assessments will be conducted before the waiting period, before beginning of the intervention, two weeks after beginning of the intervention (+2 weeks), +4 weeks, +12 weeks, and follow ups at +6 months and +12 months.,Treatment,Single (Care Provider),Care providers (providing guidance) are not informed about wether participants have been assigned to the online support program condition or the comparator condition, consisting of a waiting period followed by the online support program.","gender:All,Min Age:18 Years,Max Age:N/A",No,600
NCT04499677,Recruiting,"September 24, 2020","March 1, 2021",COVID-19,"Randomized,Factorial Assignment,Randomised, double-blind, 2x2 factorial placebo-controlled,Treatment,Triple (Participant, Care Provider, Investigator),Double-blind","gender:All,Min Age:18 Years,Max Age:70 Years",No,240
NCT04466306,Enrolling by invitation,"April 15, 2020","July 1, 2021","Acute Kidney Injury,COVID","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:25 Years",No,250
NCT04413955,Recruiting,"June 1, 2020","December 31, 2021","COVID-19,SARS-CoV 2","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04575168,Not yet recruiting,October 2020,November 2020,Covid19,"Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04396353,"Active, not recruiting","June 4, 2020","January 20, 2021","COVID-19,SARS-CoV 2,Corona Virus Infection,Sedentary Behavior","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1574
NCT04368728,Recruiting,"April 29, 2020","December 11, 2022","SARS-CoV-2 Infection,COVID-19","Randomized,Parallel Assignment,Prevention,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:16 Years,Max Age:N/A",No,43998
NCT04371302,Not yet recruiting,"May 1, 2020","June 30, 2020","Burnout, Professional,Medical Errors,Depression","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,145
NCT04487886,Not yet recruiting,August 2020,February 2022,COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Care Provider)","gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04323631,Withdrawn,"April 30, 2020","April 30, 2020",COVID-19,"Randomized,Sequential Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04358029,Recruiting,"April 9, 2020",December 2021,"COVID 19 Cardiac,COVID 16 Arrhythmia,COVID 19 Death","Case-Only,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,10000
NCT04343664,Not yet recruiting,"August 1, 2020","December 31, 2020","Mental Stress,Mental Health Wellness 1,Depression,Anxiety,Behavior Problem,Emotional Problem","Ecologic or Community,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:4 Years,Max Age:N/A",No,10000
NCT04508712,Not yet recruiting,"August 10, 2020","August 31, 2021",COVID-19,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,900
NCT04444271,Recruiting,"May 1, 2020","September 30, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:10 Years,Max Age:N/A",No,20
NCT04362956,Recruiting,"July 10, 2020","September 30, 2020","Covid19,Pregnancy Related,Neonatal Infection","Case-Control,Prospective","sampling_method:Probability Sample,gender:Female,Min Age:N/A,Max Age:N/A",No,200
NCT04379245,Completed,"April 30, 2020","May 4, 2020","HIV,Pre-exposure Prophylaxis","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,4200
NCT04386616,Recruiting,"June 2, 2020","March 3, 2021",COVID-19 Pneumonia,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,390
NCT04456426,Not yet recruiting,July 2020,August 2020,"COVID,SARS-CoV 2,SARS Pneumonia,SARS (Disease),SARS (Severe Acute Respiratory Syndrome)","Ecologic or Community,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:120 Years",No,250
NCT04345679,Not yet recruiting,"April 14, 2020","April 1, 2021",COVID 19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04335279,Completed,"April 9, 2020","July 24, 2020","Scleroderma,Scleroderma, Systemic,Systemic Sclerosis","Randomized,Parallel Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,172
NCT04343989,Recruiting,"March 31, 2020","July 1, 2020",COVID-19,"Randomized,Parallel Assignment,This is a randomized, double-blind, placebo-controlled, adaptive seamless Phase II/III design (ASD). We propose the administration of an investigational drug in patients with high predicted short-term mortality secondary to COVID-19 disease. 80 patients were randomly assigned in a 1:1:1 ratio to three study arms that will receive clazakizumab at a dose of 12.5 mg, 25 mg or placebo. Interim analyses have occurred every 7 days since the enrollment of the first 30 patients. Based on week 4 interim analysis the DSMB has recommendation discontinuing the low-dose 12.5 mg of clazakizumab arm. The DSMB has advised continuing enrollment in the placebo and high-dose 25mg of clazakizumab arms in a 1:1 randomization.,Treatment,Double (Participant, Investigator),This study is double-blind and therefore neither the Investigator, the subject, the Sponsor and its representatives, nor other designated study site personnel involved in running of the study will be aware of the identification of the investigational drug administered to each subject.","gender:All,Min Age:18 Years,Max Age:N/A",No,90
NCT04341441,Recruiting,"April 7, 2020","April 30, 2021","COVID-19,Coronavirus,Coronavirus Infections,SARS-CoV 2","Randomized,Parallel Assignment,This is a prospective, multi-site study designed to evaluate whether the use of hydroxychloroquine in healthcare workers (HCW) and first responders (FR) in southeast (SE) Michigan, can prevent the acquisition, symptoms and clinical COVID-19 infection.
The study will randomize a total of 3,000 Healthcare Workers and First Responders, age ≥18 years or older, through the Henry Ford Health System, Detroit COVID Consortium. The participants who meeting study entry criteria and are not on HCQ prior to study enrollment will be randomized in a 1:1:1 blinded comparison of daily or weekly oral hydroxychloroquine versus oral placebo for 8 weeks.
A fourth non-randomized comparator group will be enrolled in the study comprising of HCW who are chronically on HCQ as part of their standard of care for their autoimmune disease(s). This will be an open enrollment group and will provide information of chronic weight-based daily therapy of HCQ effectiveness as a prophylactic/preventive strategy.,Prevention,Triple (Participant, Care Provider, Investigator),Blinded randomization will be performed by the Henry Ford Hospital Public Health Sciences investigators once the participants are determined to be eligible for enrollment. Randomization will be stratified by study site and risk of exposure based on location of work and type of work.
Once enrolled, each Participant will be assigned a unique identifier (detailed in the full protocol). This number, along with the assigned site number, will constitute the Subject Identifier (Subject ID).","gender:All,Min Age:18 Years,Max Age:75 Years",No,3000
NCT04316728,Not yet recruiting,March 2020,November 2020,Coronavirus Infections,"N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04573361,Completed,"May 2, 2020","May 27, 2020","Musculoskeletal Pain,Disability Physical,Psychological Distress","Non-Randomized,Parallel Assignment,Three arms depending on the access to chiropractic care (no access, one visit or more than one) during the 14-days period of the trial. Measures were taken at the beginning and at the end of the 14-day period.,Treatment,None (Open Label),Care was provided by chiropractors,","gender:All,Min Age:14 Years,Max Age:N/A",No,723
NCT04422769,Recruiting,"May 22, 2020","December 31, 2020",Spinal Cord Injuries,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,250
NCT04445220,Not yet recruiting,September 2020,July 2021,"COVID-19,Acute Kidney Injury","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,22
NCT04318431,Completed,"April 14, 2020","June 1, 2020",Covid19,"N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:N/A,Max Age:15 Years",No,605
NCT04366063,Recruiting,"April 5, 2020","December 10, 2020",Covid-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:65 Years",No,60
NCT04346277,Available,N/A,N/A,N/A,N/A,"gender:All,Min Age:18 Years,Max Age:70 Years",N/A,N/A
NCT04355611,Recruiting,"April 20, 2020","April 20, 2022","Multiple Sclerosis,NMO Spectrum Disorder,COVID-19","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,2000
NCT04333420,Recruiting,"March 31, 2020","August 31, 2021",Severe COVID-19 Pneumonia,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator),Phase II: Open label study (30 patients) Phase III: Double- blind; (360 patients)","gender:All,Min Age:18 Years,Max Age:N/A",No,390
NCT04331054,Recruiting,"April 13, 2020","January 13, 2022","Covid-19 Infection,Hospitalization in Respiratory Disease Department","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,436
NCT04386850,Recruiting,"April 14, 2020","March 15, 2021",COVID 19,"Randomized,Parallel Assignment,This is a multicenter randomized double-blinded placebo-controlled clinical trial with parallel groups and allocation 1:1.,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),All subjects in a stratified random sampling method based on age, sex, BMI and serum level of 25(OH)D (<10 ng/dL vs 10 to <20 ng/dL) with serum calcium <=10.6 mg/dL will be recruited in the 25(OH)D3 or placebo group. The clinical coordinator will determine this with a computer-generated randomization program. Subjects in the case group will receive 25 mcg of 25(OH)D3 once daily at bedtime for 2 months and the control group will receive placebo daily for 2 months.","gender:All,Min Age:18 Years,Max Age:75 Years",No,1500
NCT04341103,Not yet recruiting,"April 1, 2020","March 1, 2021","Solid Organ Transplant Rejection,COVID-19","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,500
NCT04568876,Not yet recruiting,October 2020,November 2021,Covid19,"Randomized,Parallel Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04381936,Recruiting,"March 19, 2020",December 2031,Severe Acute Respiratory Syndrome,"Randomized,Factorial Assignment,Main randomisation (part A): Eligible patients will be randomly allocated between the available treatment arms.
Main randomisation (part B): Simultaneously, eligible patients will be randomly allocated between convalescent plasma, synthetic neutralizing antibodies or no additional treatment.
Subsequent randomisation: Participants with progressive COVID-19 (as evidenced by hypoxia and an inflammatory state) may undergo an optional second randomisation.,Treatment,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,15000
NCT04389385,"Active, not recruiting","May 1, 2020","May 31, 2021","Corona Virus Infection,Pneumonia","N/A,Single Group Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,60
NCT04448717,Recruiting,"June 16, 2020",March 2021,"SARS-CoV 2,COVID-19","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:5 Years,Max Age:N/A",No,8000
NCT04425382,Recruiting,"March 1, 2020",September 2020,"Coronavirus,COVID,Pneumonia","Other,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04443075,Recruiting,"June 24, 2020","August 30, 2020","Stress Disorders, Post-Traumatic","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:50 Years",No,180
NCT04341727,Suspended,"April 4, 2020","August 1, 2021",Coronavirus Infection,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04377750,Recruiting,"April 8, 2020","May 8, 2021",Covid19 Pneumonia,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04409275,Recruiting,"May 21, 2020","July 31, 2021",Pulmonary Fibrosis,"Case-Only,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:90 Years",No,500
NCT04403100,Recruiting,"June 3, 2020","November 28, 2020","COVID-19,Coronavirus Infection,Virus Disease,Acute Respiratory Infection,SARS-CoV Infection","Randomized,Factorial Assignment,Patients will be randomly allocated to one of four treatment arms in a 1:1:1:1 ratio:
Lopinavir / Ritonavir
Hydroxychloroquine
Lopinavir / Ritonavir + Hydroxychloroquine
Placebo.
We will use a centralized random allocation schedule, generated by computer and implemented using an online remote access system. Randomization will be stratified by participating basic health unit.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),The investigational medical product will be packaged in similar bottles by a third party who will keep the allocation confidential until the end of the study. The bottles will be sealed and identified as ""Research Product A, B and C"" and with different colored labels. They will be randomly allocated among the participants. The research subjects, medical assistance, administrative and health staff will not have access to the contents of the bottles. The Arm Lopinavir/ ritonavir plus hydroxychloroquine will receive two of such bottles.
At the end of the study, after the statistical analysis and DMSB meeting, it will then be requested from third party documentation on content of each bottle and then have arms identified.","gender:All,Min Age:18 Years,Max Age:N/A",No,1968
NCT04340349,Enrolling by invitation,"May 11, 2020","August 20, 2020","Hydroxychloroquine,Antimalarials,Enzyme Inhibitors,Antirheumatic Agents","Randomized,Parallel Assignment,Parallel Assignment,Prevention,Triple (Participant, Care Provider, Investigator),DOUBLE BLINDED","gender:All,Min Age:18 Years,Max Age:N/A",No,140
NCT04560205,Recruiting,"May 1, 2020","October 30, 2020",SARS-CoV Infection,"N/A,Single Group Assignment,quasi-experimental,Treatment,None (Open Label)","gender:All,Min Age:15 Years,Max Age:80 Years",No,50
NCT04452422,Recruiting,"June 23, 2020","September 23, 2020",Deep Venous Thrombosis,"Case-Only,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04350320,Recruiting,"April 30, 2020","November 20, 2020",COVID19,"Randomized,Parallel Assignment,Phase III, prospective, randomized, controlled, open-label and pragmatic trial, comparing the administration of colchicine plus standard treatment vs. standard therapy, in hospitalized patients with COVID-19, within the first 48 hours, and no severity criteria,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,102
NCT04345445,Not yet recruiting,"April 15, 2020","October 31, 2020",COVID-19,"Randomized,Crossover Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,310
NCT04367870,Recruiting,"May 23, 2020",May 2021,Oncology,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2500
NCT04416464,Not yet recruiting,"June 15, 2020","October 1, 2022","Quality of Life,Long-term Outcomes,Coronavirus Infection,Morality,Rehospitalization","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,230
NCT04493242,Not yet recruiting,"September 1, 2020","December 31, 2020","Covid19,ARDS,Pneumonia, Viral","Randomized,Parallel Assignment,Multi-center, placebo-controlled, randomized clinical trial.,Treatment,Single (Investigator)","gender:All,Min Age:18 Years,Max Age:85 Years",N/A,60
NCT04381338,Not yet recruiting,"May 10, 2020","September 30, 2020","Corona Virus Disease 19 (COVID-19),COVID,Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS),Critical Illness","Non-Randomized,Parallel Assignment,Clustered, due to catchment area of Hospital with no chance of contamination because of lock down in the area.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,92
NCT04273763,"Active, not recruiting","February 16, 2020","June 1, 2020","Novel Coronavirus Pneumonia,2019-nCoV","Randomized,Sequential Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,18
NCT04470609,Enrolling by invitation,"July 10, 2020",November 2021,COVID-19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:60 Years,Max Age:N/A",No,471
NCT04563065,Recruiting,"August 1, 2020","December 31, 2023","Pregnancy Complications,Pregnancy, High Risk,Pregnancy Induced Hypertension,Newborn Morbidity,Fetal Growth Retardation,Fetus Disorder,Weight Gain, Maternal,Maternal-Fetal Relations","Randomized,Parallel Assignment,Prevention,Single (Outcomes Assessor)","gender:Female,Min Age:18 Years,Max Age:50 Years",No,280
NCT04449783,Recruiting,"June 25, 2020","September 25, 2020","Covid19,Cancer","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04369469,Recruiting,"May 11, 2020",February 2021,"COVID-19 Severe Pneumonia,Acute Lung Injury,Acute Respiratory Distress Syndrome,Pneumonia, Viral","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,270
NCT04550312,Recruiting,September 2020,October 2020,"Lifestyle Alteration,Non-COVID Deaths","Other,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,80000
NCT04408391,Withdrawn,"May 20, 2020","July 6, 2020","Covid-19,Anosmia","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT03808922,Recruiting,"May 23, 2019","December 28, 2021","Lower Respiratory Tract Infection,Parainfluenza,Immunocompromised,COVID-19","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:N/A,Max Age:N/A",No,250
NCT04407169,Not yet recruiting,"June 1, 2020","August 1, 2020",COVID,"Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04466657,Not yet recruiting,"November 1, 2020","April 30, 2021",Covid-19,"Randomized,Parallel Assignment,Supportive Care,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:75 Years",No,90
NCT04361942,Recruiting,April 2020,"December 31, 2020",COVID-19 Pneumonia,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator),Both experimental and Placebo will receive a similar endovenous injection with either cells or placebo. Blind to participant, investigator ans care providers","gender:All,Min Age:18 Years,Max Age:N/A",No,24
NCT04421625,Recruiting,"June 15, 2020","June 15, 2022",COVID-19,"N/A,Single Group Assignment,Screening,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,12000
NCT04372056,Recruiting,"May 6, 2020","May 6, 2021","COVID-19,Critical Care,Intensive Care Units,Health Personnel","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:20 Years,Max Age:N/A",No,2200
NCT04361344,Recruiting,"May 19, 2020","January 19, 2021","COVID-19 Infection,Encephalitis","N/A,Single Group Assignment,Prospective, descriptive, monocentric, non-controlled study,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04507230,Recruiting,"August 7, 2020",October 2020,Coagulopathy,"Cohort,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04536935,Not yet recruiting,September 2020,December 2020,"Depression,Anxiety,Emotional Regulation","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:19 Years,Max Age:N/A",No,2000
NCT04438967,Recruiting,"June 16, 2020","December 31, 2020",Brain Health,"Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,10000
NCT04498546,Recruiting,"July 20, 2020","September 30, 2021",Exercise Test,"Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:65 Years",No,60
NCT04428801,Not yet recruiting,"August 1, 2020","October 30, 2021",COVID-19,"Randomized,Parallel Assignment,The Phase 2 study is a randomized, double-blind, placebo-control study conducted in multiple clinic facilities.,Treatment,Double (Participant, Outcomes Assessor),Patients and evaluators","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04445389,Recruiting,"June 17, 2020","June 17, 2022",SARS-CoV-2,"Randomized,Parallel Assignment,Prevention,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:50 Years",No,210
NCT04373213,Not yet recruiting,"May 5, 2020","June 15, 2020",Pleth Variability Index,"Case-Control,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04512300,Completed,"June 15, 2020","June 25, 2020",Dental Treatment During Covid -19,"Other,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,267
NCT04374058,"Active, not recruiting","March 20, 2020",March 2021,End Stage Renal Disease,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:85 Years",No,50
NCT04480957,Recruiting,"August 4, 2020",January 2021,SARS-CoV-2,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:21 Years,Max Age:80 Years",No,92
NCT04392414,Completed,"May 1, 2020","September 23, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,60
NCT04392245,Completed,"April 15, 2020","April 26, 2020",Proctologic Practice During COVID-19,"Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1050
NCT04477902,Recruiting,"July 1, 2020","July 1, 2022","Covid19,Corona Virus Infection,Quality of Life,Risk Reduction","Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,50000
NCT04325646,Recruiting,"March 13, 2020","February 28, 2023","SARS (Severe Acute Respiratory Syndrome),COVID-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:5 Years,Max Age:N/A",No,2000
NCT04403828,Completed,"May 20, 2020","July 15, 2020",COVID 19,"Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:75 Years",No,323
NCT04336761,Recruiting,"April 15, 2020",January 2021,"Coronavirus,COVID,Infection Viral","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:18 Years",No,914
NCT04470427,Recruiting,"July 27, 2020","October 27, 2022",SARS-CoV-2,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,30000
NCT04346979,Not yet recruiting,"August 1, 2020","November 1, 2020",Telerehabilitation,"Randomized,Parallel Assignment,Treatment,Single (Participant)","gender:Female,Min Age:45 Years,Max Age:65 Years",No,50
NCT04379375,Terminated,"July 27, 2020","September 30, 2020","Health Behavior,COVID-19","Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,45
NCT04531774,Recruiting,"August 28, 2020","June 1, 2021","Stress,Burnout,Anxiety,Depression,Covid19","Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,160
NCT04398264,Recruiting,"July 22, 2020","March 31, 2021","Corona Virus Infection,Pregnancy Related","Cohort,Other","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:N/A",No,100
NCT04426266,Completed,"May 1, 2020","September 28, 2020","Questionnaire Designs,COVID-19 Pandemic,Psychological Stress,Coping Skills,Two-Item Generalised Anxiety Disorder Scale,Patient Health Questionnaire Anxiety and Depression Scale,Health Status Index,Subjective Health Complaint,Mood","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,441
NCT04497987,Recruiting,"August 2, 2020","June 29, 2021","COVID-19,SARS-CoV2","Randomized,Parallel Assignment,Prevention,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,2400
NCT04367714,Recruiting,"March 15, 2020","December 1, 2021","COVID,Terminal Renal Insufficiency","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04517123,Recruiting,"September 1, 2020","December 31, 2021","Covid19,Pneumonia, Viral","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04339608,Recruiting,"April 2, 2020","June 30, 2020",COVID-19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,10000
NCT04530448,Not yet recruiting,"September 30, 2020",March 2021,"COVID,Coronavirus,Coronavirus Infection,AKI,Acute Kidney Injury","Randomized,Parallel Assignment,Group 1 (control) will receive standard of care treatment for coronavirus according to institutional protocols.
Group 2 (treatment) will receive sodium bicarbonate 225 mEq (225 mL of an 8.4% solution) intravenously over 1 hour.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04542200,Enrolling by invitation,"January 1, 2021","December 31, 2022",Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,70812
NCT04534608,"Active, not recruiting","May 11, 2020","March 31, 2021","SARS-CoV-2,Covid19","Family-Based,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:18 Years",No,6000
NCT04402866,Recruiting,"June 24, 2020",October 2020,"Acute Lung Injury (ALI) Associated With COVID-19,Lung Inflammation Associated With COVID-19","Randomized,Parallel Assignment,Parallel group, randomized, double-blind, placebo-controlled,Treatment,Triple (Participant, Care Provider, Investigator),Pharmacist & Sponsor are not blinded for Part 1. Pharmacist & Sponsor are blinded for Part 2.","gender:All,Min Age:18 Years,Max Age:80 Years",No,159
NCT04383886,Recruiting,"April 18, 2020","August 18, 2020","Emergency Department Staff During the COVID-19 Pandemic,Emergency Department Staff's Level of Stress","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04497389,Not yet recruiting,"September 15, 2020","September 15, 2021",SARS CoV-2,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04536376,Not yet recruiting,"November 1, 2020","December 31, 2021","Resilience,Stress,Sleep","N/A,Single Group Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,10
NCT04426253,"Active, not recruiting","June 5, 2020","July 31, 2021","COVID-19,Sars-CoV2","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04445441,Recruiting,"April 24, 2020","December 31, 2020",Coronavirus Infection,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:99 Years",No,150
NCT04369365,Recruiting,"April 27, 2020","December 27, 2020",COVID,"Randomized,Parallel Assignment,Prevention,Single (Participant)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04491071,Not yet recruiting,September 2020,December 2020,Stress Disorder,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,405
NCT04550325,Recruiting,"August 5, 2020",February 2021,"Covid19,Pneumonia, Viral","N/A,Single Group Assignment,A Phase 1/2 Open Label, Single Arm Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of Single Dose Kamada Anti-SARS-CoV-2 in COVID-19 Hospitalized Patients with Pneumonia,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,12
NCT04568096,Not yet recruiting,September 2020,November 2020,the Lung Complication of COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,160
NCT04395807,Recruiting,"June 3, 2020",May 2021,"COVID,Acute Hypoxemic Respiratory Failure","Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04377737,Withdrawn,"May 15, 2020",September 2020,"Infection; Viral, Coronavirus","N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:3 Years,Max Age:10 Years",No,0
NCT04435522,Recruiting,"September 21, 2020",January 2021,COVID,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:99 Years",No,16
NCT04441489,Completed,"March 27, 2020","May 27, 2020","COVID-19,FDG PET/CT,Inflammation","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:99 Years",No,13
NCT04362111,Recruiting,"July 29, 2020",March 2021,"Cytokine Storm,COVID-19","Randomized,Parallel Assignment,Two parallel treatment arms,Treatment,Triple (Participant, Care Provider, Investigator),Investigator, care provider, and participant blinded","gender:All,Min Age:18 Years,Max Age:80 Years",No,30
NCT04395716,Not yet recruiting,July 2020,November 2021,"COVID,Covid-19,Corona Virus Infection,Sars-CoV2,Coronavirus-19,SARS Pneumonia,SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,50
NCT04514900,Recruiting,"September 23, 2020","September 15, 2021",Obesity,"Randomized,Factorial Assignment,A 2x2 randomized controlled pilot study will be conducted which randomly allocates up to 120 individuals with overweight or obesity to an online weight control program and varies whether they receive asynchronous social support (discussion board) vs synchronous plus asynchronous social support (weekly video chat + discussion board) and varies whether the type of feedback which they receive on their self-monitoring (detailed vs basic) in a factorial study. All participants will receive the core 16-week online interactive behavioral weight loss program (iREACH) and will be followed for 4 months with monthly surveys and weight ascertainment.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04508439,Recruiting,"June 20, 2020","December 30, 2020","Covid19,Pneumonia,Coagulation Disorder,Pulmonary Embolism","Randomized,Crossover Assignment,Initially they will be randomized into two blocks, the first based on prophylactic Enoxaparin (Numbers 1 to 64) and the second (Numbers 65 to 128) will be assigned to the Enoxaparin therapeutic regimen arm at doses of 1mg / kg/dose twice up to date
During hospitalization, the clinical evolution will be evaluated according to the requirements of mechanical ventilation, the reduction in D-Dimer levels and the clinical outcome (discharge or death).
Those patients who are discharged will be Randomized in two following treatment arms
The allocation of patients in the outpatient stage will be carried out randomly 1: 1 to receive Rivaroxaban 10mg PO every 24hrs or only clinical follow-up.
Follow-up of adverse events will be carried out in the Hematology outpatient clinic with a first consultation 15 days after discharge and a second consultation 30 days after discharge. With dimer D, ferritin, protein C, blood count, ESR and on day 30 with CAT.,Treatment,Double (Participant, Care Provider)","gender:All,Min Age:18 Years,Max Age:90 Years",No,130
NCT04563702,Recruiting,September 2020,October 2021,Covid19,"Non-Randomized,Sequential Assignment,Open-label, repeat dose, dose ranging,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:54 Years",No,48
NCT04344106,Recruiting,"April 1, 2020","May 1, 2020","Coronavirus Infection,Oxygen Deficiency","N/A,Single Group Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,25
NCT04536350,Not yet recruiting,September 2020,March 2022,"Covid19,Corona Virus Infection,ARDS,Aviptadil","Randomized,Parallel Assignment,Patients will be randomly allocated to receive either Aviptadil together with standard care or the placebo (NaCl 0.9%) together with standard care,,Treatment,Double (Participant, Investigator),Patients and the investigator administering inhalation devices of drug or placebo are not aware of which group they have been randomized to (double-blinded). Someone not involved in the study (e.g. the hospital pharmacist or a nurse not involved in study) prepares the inhalation devices with either drug or placebo according to the randomization plan received by the CTU","gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04406246,Recruiting,"May 21, 2020","December 31, 2020",Coronavirus Infection,"N/A,Single Group Assignment,In this cohort study, all health workers of the Maternal-Perinatal Hospital ""Mónica Pretelini Sáenz"", with symptoms of SARS-CoV-2 will be treated promptly with nitazoxanide.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,150
NCT04367337,"Active, not recruiting","March 25, 2020","March 24, 2021",Health Behavior,"Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,6079
NCT04492384,Recruiting,"June 11, 2020","January 15, 2022","Covid19,SARS-CoV-2 Infection,Pneumonia,Copd,CKD,Cardiac Event,Overweight and Obesity,Cardiovascular Diseases,Diabetes,Hypertension,Coronary Heart Disease","Cohort,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,3500
NCT04525404,Not yet recruiting,November 2020,"September 1, 2021","Covid19,Coronavirus Infection,SARS-CoV Infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,228
NCT04360278,Recruiting,"April 21, 2020","April 14, 2030",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1500
NCT04346615,Recruiting,"April 25, 2020",April 2021,COVID-19 Infection,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04377607,Recruiting,"November 1, 2020","December 30, 2020",Corona Virus Infection,"Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,200
NCT04393636,Recruiting,"June 5, 2020","December 31, 2022","Cardiovascular Diseases,Cardiovascular Risk Factor","Randomized,Parallel Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,394
NCT04473599,Recruiting,"April 17, 2020","April 1, 2021","Depressive Symptoms,Anxiety,COVID-19","Randomized,Parallel Assignment,Prevention,Single (Participant),Participants are randomized to receive messages according to a random schedule (within a mico-randomized trial) or delivered via a reinforcement learning policy","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04500067,Recruiting,"May 7, 2020","September 30, 2020","Covid19,Pneumonia","Randomized,Parallel Assignment,Open-label multicenter randomized controlled in parallel groups.
Patients undergoing screening are randomized into groups in equal proportions:
Study Group (receive IVIG Bioven with base therapy).
Control group (receive base therapy only)
At the stage of Data Analysis to ensure comparability of data and homogeneity of the sample, the possibility of additional comparison of groups based on the actually prescribed base therapy and other identified covariates is provided.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,76
NCT04578236,Not yet recruiting,November 2020,January 2021,Covid19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,360
NCT04573868,Recruiting,"March 1, 2020","September 30, 2020",Mortality,"Case-Only,Prospective","sampling_method:Probability Sample,gender:All,Min Age:14 Years,Max Age:N/A",No,1000
NCT04329611,Terminated,"April 13, 2020","July 20, 2020",COVID-19,"Randomized,Single Group Assignment,Randomization will be conducted using an online tool. The use of an online tool will allow for dynamic randomization which ensures concealment of allocation. We will use a minimal sufficient balance randomization tool to ensure balance on age, sex, risk status (binary variable based on immune competence and other identified risks), days from symptom onset to randomization and provincial health zone (5 categories). These variables will be identified at telephone screening by a study coordinator, clarified with a physician when necessary, and entered into the online randomization tool. It is predicted that many patients will want treatment. Further, immunosuppressed patients may be at the highest risk of fatal outcomes. Therefore, we will use 2:1 randomization (HCQ: placebo).,Treatment,Triple (Participant, Care Provider, Investigator),A randomized, double-blind, placebo-controlled trial - trial staff and patients will all be blinded to the treatment allocation.","gender:All,Min Age:18 Years,Max Age:N/A",No,148
NCT04424797,Recruiting,"July 13, 2020",December 2020,COVID-19,"Randomized,Parallel Assignment,Prone vs. Supine positioning,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04456933,Recruiting,"June 29, 2020","February 28, 2022",Colon Cancer,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,148
NCT04377685,Recruiting,"March 1, 2020","September 30, 2020",COVID 19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,800
NCT04283461,"Active, not recruiting","March 16, 2020","November 22, 2021","COVID-19,COVID-19 Immunisation","Non-Randomized,Sequential Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:99 Years",No,120
NCT04498442,Recruiting,"May 22, 2020","December 31, 2020","Covid19,Stress,Anxiety Depression","Randomized,Parallel Assignment,In this prospective randomized control trial, the effects of yoga practices are being compared between seasoned yoga practitioners with two controls who are age and gender matched and living in the same neighborhood.
One control group acts as active control who receives active intervention in the form of yoga activities during the study duration. The study provides its active control group an opportunity to learn and practice Simha-Kriya which involves deep breathing exercises and meditation. In contrast, the other control group acts as a placebo control and performs either reading activities or remains idle for 15 minutes throughout the study period.
The participants will be requested to complete a set of surveys as a part of the research activity. These surveys include validated scales on stress, resilience and well-being; and objective questions on COVID-19 infection and medical history.,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,30000
NCT04359693,Completed,"April 22, 2020","July 1, 2020",SARS-CoV 2,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1576
NCT04465656,Recruiting,"July 7, 2020","April 30, 2021",Pulmonary Embolism,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,250
NCT04386694,Recruiting,"May 18, 2020",July 2020,"COVID-19,Respiratory Failure","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),A researcher will program the device (PMBT/sMF or placebo) and will be instructed not to inform the patients or other researchers as to the type of treatment (PMBT/sMF or placebo). Therefore, the therapist responsible for the treatment, the investigators and the outcome assessors will be blinded to the type of treatment being administered to the patients. The sounds and signals emitted from the device as well as the information displayed on the screen will be identical, regardless of the type of treatment (PBMT/sMF or placebo).","gender:All,Min Age:15 Years,Max Age:N/A",No,30
NCT04390269,Not yet recruiting,"September 10, 2020","May 9, 2022",Genetic Predisposition to Disease,"Case-Control,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04456101,Recruiting,"June 19, 2020","June 1, 2022",COVID-19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,240
NCT04403932,Recruiting,"April 17, 2020","July 1, 2020",Coronavirus Disease 2019 (COVID-19),"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04384887,Completed,"April 25, 2020","August 26, 2020","COVID,Anxiety,Depression, Postpartum","Case-Control,Prospective","sampling_method:Probability Sample,gender:Female,Min Age:18 Years,Max Age:45 Years",No,100
NCT04353011,Completed,"April 20, 2020","April 27, 2020","Sars-CoV2,Chronic Pain","Family-Based,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,312
NCT04478071,Recruiting,"August 22, 2020","August 1, 2022","Acute Respiratory Distress Syndrome,Coronavirus Infection","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04561154,Recruiting,"June 11, 2020","June 11, 2022","SARS-COV2,COVID19","N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,134
NCT04385797,"Active, not recruiting","May 4, 2020","August 31, 2020","Mild Cognitive Impairment,Dementia","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:55 Years,Max Age:N/A",No,152
NCT04401410,Not yet recruiting,"October 30, 2020","August 15, 2021","SARS-CoV 2,Viral Infection,COVID 19","Randomized,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,58
NCT04460469,Recruiting,"July 1, 2020",September 2020,"Anxiety,Covid19,Oral Hygiene","Other,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1500
NCT04405934,Not yet recruiting,July 2020,April 2021,"Covid-19,Nosocomial Infection,Coronavirus,Coronavirus Infection,SARS-CoV 2","Sequential Assignment,Superiority model:
Baseline/control phase 1 Sample collection and genomic sequencing from Covid-19 positive participants suspected of acquiring infection in hospital (suspected nosocomial Covid-19 infection where tested positive >48 hours after hospital admission) where sequencing reports not interpreted/actioned by Infection Prevention Control (IPC) site teams
Site intervention phase Sample collection and genomic sequencing from Covid-19 positive participants suspected of acquiring infection in hospital where sequencing reports generated both rapid or standard and received by site IPC teams for interpretation and action
Control phase 2 (prospective) Sample collection and genomic sequencing from Covid-19 positive participants suspected of acquiring infection in hospital where sequencing reports not interpreted/actioned by IPC site teams - where deemed ethical and approved by oversight committees i.e. DMEC.,Health Services Research,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,2000
NCT04331171,Recruiting,"March 17, 2020","July 31, 2020",COVID-19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,3000000
NCT04388605,Recruiting,"April 21, 2020",September 2022,"Corona Virus Infection,COVID,Pregnancy Related,Early Pregnancy","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:N/A",No,11000
NCT04492358,Not yet recruiting,September 2020,October 2021,Covid19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:65 Years,Max Age:N/A",No,144
NCT04353518,Not yet recruiting,"April 30, 2020","May 30, 2021",COVID-19,"Randomized,Parallel Assignment,Randomized, double-blind, two arms, placebo controlled, clinical trial,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,4000
NCT04484545,"Active, not recruiting","April 1, 2020","June 1, 2021",COVID-19,"Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,250
NCT04407533,Recruiting,"May 25, 2020","August 31, 2022",COVID-19,"Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1920
NCT04456413,Not yet recruiting,October 2020,July 2021,COVID-19,"Randomized,Crossover Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,306
NCT04495842,Not yet recruiting,"August 1, 2020","April 30, 2021","Stress,Covid19,Anxiety","Randomized,Parallel Assignment,Supportive Care,Single (Participant)","gender:All,Min Age:18 Years,Max Age:65 Years",No,65
NCT04370197,Recruiting,"March 3, 2020","April 30, 2020","Stroke, Acute","Case-Only,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04279782,Recruiting,"January 20, 2020","February 28, 2021",Coronavirus,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04444661,"Active, not recruiting","June 10, 2020","December 31, 2020","Osteoporosis,Sarcopenia","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:Male,Min Age:74 Years,Max Age:95 Years",No,21
NCT04531735,"Active, not recruiting","March 1, 2020","August 31, 2020","RSV Infection,Covid19","Case-Control,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:1 Month",No,28
NCT04341675,Recruiting,"April 24, 2020",September 2020,COVID-19,"Randomized,Parallel Assignment,Randmized, double blind, placebo controlled,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04542915,Not yet recruiting,September 2020,October 2021,"SARS-CoV Infection,Anxiety,Depression,Occupational Problems,Severe Acute Respiratory Syndrome,Coronavirus Infection","Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,5000
NCT04337190,Recruiting,"April 3, 2020","December 6, 2020","COVID,Acute Respiratory Distress Syndrome","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04535778,Not yet recruiting,"September 28, 2020","June 1, 2021",Treatment of Illness-related Distress in Physical LTCs,"Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04434157,Completed,"March 28, 2020","May 5, 2020",Covid-19,"Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,221
NCT04336254,Recruiting,"April 6, 2020","March 31, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:65 Years",No,20
NCT04347993,Recruiting,"March 27, 2020",April 2021,COVID-19,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,5000
NCT04392973,Recruiting,"May 21, 2020",November 2021,COVID19,"Randomized,Parallel Assignment,Randomized, open-label, parallel groups were participants are assigned to either an intervention arm or standard of care.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,520
NCT04507893,Recruiting,"March 15, 2020","December 1, 2020","Covid19,Interstitial Pneumonia","Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:95 Years",No,80
NCT04507256,Recruiting,"August 18, 2020","September 14, 2021",COVID-19,"Randomized,Sequential Assignment,Treatment,Double (Participant, Investigator),The study will be blinded for all placebo controlled dose groups, ie, the Principal Investigator (PI), all clinical staff involved in the clinical study, the participants, and the study monitor will remain blinded, unless safety concerns or a regulatory requirement necessitate unblinding.","gender:All,Min Age:18 Years,Max Age:55 Years",No,48
NCT04344002,Recruiting,"April 21, 2020","December 15, 2020","Covid-19,Lung Cancer","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,200
NCT04505722,Recruiting,"September 7, 2020","March 10, 2023",Participants With or Without Stable Co-morbidities Associated With Progression to Severe COVID-19 at Different Stages of the Protocol,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,60000
NCT04368975,Recruiting,"March 12, 2020","December 31, 2020",Acute Respiratory Failure With Hypoxia,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04374071,Completed,"March 12, 2020","April 30, 2020","COVID,Pneumonia, Viral","Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,250
NCT04305574,Completed,"March 7, 2020","April 21, 2020","Coronavirus,Depression,Anxiety,Stress","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:21 Years,Max Age:N/A",No,1145
NCT04468035,Recruiting,"June 1, 2020","December 31, 2021",Covid19,"Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04366323,Recruiting,"April 27, 2020",October 2021,Sars-CoV2,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,26
NCT04354519,Recruiting,"March 14, 2020","July 14, 2022","Multiple Sclerosis,COVID-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,3000
NCT04525417,Recruiting,"April 25, 2020","October 25, 2020",Covid-19 Immune Status of Healthcare Workers,"Non-Randomized,Parallel Assignment,Monocentric, open-label, prospective, non-randomized study,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04373811,Recruiting,"April 16, 2020","September 16, 2021","COVID-19,ICU Acquired Weakness,Weaning Failure","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,50
NCT04510623,Recruiting,"March 17, 2020","June 30, 2022","COVID-19,SARS-CoV2","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04542083,Not yet recruiting,"December 1, 2020","June 30, 2021","COVID-19,Acute Cardiovascular Condition,Acute Neurovascular Condition,Stroke,Acute Myocardial Infarction","Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,4000
NCT04359537,Recruiting,"May 1, 2020","September 25, 2020",COVID 19,"Randomized,Parallel Assignment,Participants fulfilling the eligibility criteria will be randomized to 4 arms by using Random Allocation Software version-2
Arm Intervention /treatment Experimental group 1: Hydroxychloroquine 400 mg twice a day 1,followed by 400 mg weekly for a total of 12 weeks
Experimental group 2:Hydroxychloroquine 400 mg on day 1 followed by 400 mg once every 3 weeks for a total of 12 weeks
Experimental group 3:Hydroxychloroquine 200 mg on day 1 followed by 200 mg once every 3 weeks for a total of 12 weeks
Control Group :Placebo 200mg will be given on day 1 followed by Placebo 200mg every three weeks for a total of 12 weeks..,Prevention,Single (Participant)","gender:All,Min Age:18 Years,Max Age:60 Years",No,200
NCT04449627,Not yet recruiting,"August 31, 2020","January 31, 2021","Anxiety Disorders,Post Traumatic Stress Disorder,Depressive Disorder,Covid19","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,125
NCT04377802,Not yet recruiting,"May 17, 2020","December 30, 2020",COVID 19,"N/A,Single Group Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:65 Years",No,400
NCT04331834,Suspended,"April 3, 2020","October 30, 2020",COVID-19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,440
NCT04442282,Not yet recruiting,"June 22, 2020","July 13, 2020","Anxiety,Depression,Interpersonal Problem,Emotion Regulation","Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,5041
NCT04378582,Completed,"May 7, 2020","August 5, 2020","SARS-CoV 2,Respiratory Distress Syndrome, Adult,Corona Virus Infection,Critical Illness","Case-Only,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:14 Years,Max Age:100 Years",No,1589
NCT04346017,Recruiting,"March 20, 2020",December 2020,COVID-19,"Non-Randomized,Parallel Assignment,Basic Science,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,200
NCT04305457,"Active, not recruiting","March 21, 2020","April 1, 2022","Coronavirus Infections,Pneumonia, Viral,Acute Respiratory Distress Syndrome","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,67
NCT04353037,Recruiting,"April 7, 2020","June 15, 2021","Coronavirus,Corona Virus Infection","Randomized,Parallel Assignment,Treatment and prevention study,Treatment,Double (Participant, Care Provider),For PATCH 2: participant and care provider are blinded. For PATCH 3: Health care worker is blinded.","gender:All,Min Age:50 Years,Max Age:75 Years",No,850
NCT04406688,Not yet recruiting,"May 25, 2020",March 2021,"Acute Kidney Injury,COVID-19,ARDS","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04385043,Recruiting,"May 1, 2020","May 15, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:60 Years",No,400
NCT04501822,Recruiting,"July 19, 2020","December 31, 2021","Covid19,Cardiac Complication","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,380
NCT04349163,Completed,"May 10, 2020","June 25, 2020",Psychological,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,280
NCT04498299,Recruiting,"September 1, 2020","November 30, 2020","Echocardiography, Stress,COVID-19,Hypertension, Pulmonary","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:45 Years",No,30
NCT04407273,"Active, not recruiting","May 14, 2020","December 30, 2020","COVID,Statin,Cardiovascular Diseases","Case-Only,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1200
NCT04422535,Recruiting,"May 29, 2020","December 1, 2020","Coronavirus Infection,Intensive Care Patients","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04315480,"Active, not recruiting","March 12, 2020",May 2020,SARS Pneumonia,"N/A,Single Group Assignment,Simon's Two-stages Optimal Design,Treatment,None (Open Label),Radiologist will be blinded for sequence","gender:All,Min Age:18 Years,Max Age:90 Years",No,38
NCT04368026,Recruiting,"March 30, 2020","December 1, 2020","Surgical Procedure, Unspecified","Other,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:25 Years,Max Age:N/A",No,350
NCT04490174,Recruiting,"August 26, 2020","June 1, 2022",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2500
NCT04568863,Recruiting,"June 20, 2020","November 30, 2020","COVID-19,SARS-CoV 2,Coronavirus Infection","Randomized,Parallel Assignment,phase II, single-center, double-blind, randomized placebo-controlled trial,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,18
NCT04328454,Recruiting,"January 30, 2020","April 15, 2020",Coronavirus,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04464395,Recruiting,"July 1, 2020","August 31, 2021",COVID-19,"Sequential Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04363047,Not yet recruiting,"May 1, 2020","May 1, 2021",SARS Virus,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,125
NCT04255940,Recruiting,"January 20, 2020","April 30, 2020",Cardiovascular Death; Major Adverse Cardiovascular Events,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,12000
NCT04374526,Recruiting,"May 27, 2020","June 30, 2021",Coronavirus Disease 2019 )COVID-19),"Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:65 Years,Max Age:N/A",No,182
NCT04416347,Recruiting,"June 15, 2020","April 30, 2022","COVID,SARS-CoV 2","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,800
NCT04516837,Recruiting,"August 31, 2020",August 2022,Immune Thrombocytopenia,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,120
NCT04536090,Not yet recruiting,November 2020,May 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04561089,Enrolling by invitation,"July 13, 2020","December 31, 2020",SARS-CoV-2,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04355026,Recruiting,"April 10, 2020","July 31, 2020",Covid-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:19 Years,Max Age:N/A",No,90
NCT04459403,Recruiting,"June 8, 2020","September 15, 2020",Corona Virus Infection,"Case-Only,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04304313,Recruiting,"February 9, 2020","November 9, 2020",COVID-19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,10
NCT04399980,"Active, not recruiting","May 20, 2020","May 31, 2021","COVID 19,SARS-CoV 2,Pneumonia","Randomized,Factorial Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04473261,Recruiting,"July 14, 2020","September 30, 2020","Covid19,SARS-CoV-2,Corona Virus Infection","Randomized,Parallel Assignment,Randomized, controlled, multi-armed, close-label, interventional study designed,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),empty capsule will be given as a placebo","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04463758,Recruiting,"May 11, 2020",October 2022,"covid19 Infection,Pregnancy Complications,Neonatal Complications","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:N/A,Max Age:N/A",No,3060
NCT04416373,Recruiting,"March 22, 2020",December 2023,"Coronavirus Infection,Pregnancy Complications,Vertical Transmission of Infectious Disease,Breastfeeding,Neonatal Infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:16 Years,Max Age:55 Years",No,300
NCT04556604,Completed,"April 10, 2020","August 14, 2020",Consent,"Ecologic or Community,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,45
NCT04463420,Recruiting,"August 15, 2020","December 15, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:75 Years",No,224
NCT04443140,Completed,"March 15, 2020","July 10, 2020","Covid-19,Preeclampsia,Pregnancy Related","Cohort,Prospective","sampling_method:Probability Sample,gender:Female,Min Age:18 Years,Max Age:40 Years",No,131
NCT04426201,Not yet recruiting,"June 22, 2020","December 31, 2020","COVID-19,Lymphocytopenia","Randomized,Parallel Assignment,randomized controlled of treatment vs placebo,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Unblinded Pharmacist will prepare blinded syringes of colorless drug or placebo","gender:All,Min Age:25 Years,Max Age:80 Years",No,48
NCT04480580,Completed,"March 30, 2020","June 30, 2020","Covid19,Surgery,SARS (Severe Acute Respiratory Syndrome)","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04382417,Recruiting,"March 26, 2020","May 31, 2021","Covid-19,Critical Illness","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04492449,Not yet recruiting,September 2020,December 2022,"Exposure During Pregnancy,Corona Virus Infection","Other,Other","sampling_method:Probability Sample,gender:Female,Min Age:16 Years,Max Age:40 Years",No,260
NCT04531319,Recruiting,"August 15, 2020","September 15, 2020",Covid19,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,60
NCT04479644,Recruiting,"July 13, 2020",March 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:49 Years",No,12
NCT04409899,"Active, not recruiting","March 20, 2020","December 31, 2020","COVID-19,Urologic Diseases,Surgery--Complications,Epidemic Disease","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,300
NCT04419571,Completed,"March 23, 2020","June 16, 2020","COVID-19,Emergency General Surgery","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,94
NCT04563156,Enrolling by invitation,"June 23, 2020","December 31, 2021",Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04397692,Recruiting,"June 13, 2020","September 30, 2020","Corona Virus Infection,COVID-19,SARS-CoV 2,Nitric Oxide,Respiratory Disease,Pneumonia, Viral,Inhaled Nitric Oxide","Randomized,Parallel Assignment,Device Feasibility,None (Open Label)","gender:All,Min Age:22 Years,Max Age:65 Years",N/A,20
NCT04435587,Not yet recruiting,July 2020,November 2021,"Asymptomatic Infections,SARS-CoV2 Infection","Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor),PCR for SAR-CoV2 detection will be performed by technician without knowledge of treatment arm","gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04537975,Not yet recruiting,"September 15, 2020","January 15, 2021","Continuous Renal Replacement Therapy,Pulmonary Edema,COVID-19","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,30
NCT04433546,Recruiting,"July 15, 2020","December 18, 2020","Acute Respiratory Distress Syndrome,Coronavirus,Hypoxic Respiratory Failure,Hypoxemic Respiratory Failure,Respiratory Complication,Respiratory Insufficiency,Cardiac Dysfunction,Pneumonia,Pulmonary Edema,Pulmonary Inflammation,Respiratory Failure,Cytokine Storm,COVID 19,SARS-CoV-2,Cardiac Event,Cardiac Complication,Cardiac Failure,Cardiac Infarct","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:85 Years",No,210
NCT04461353,"Active, not recruiting","June 25, 2020","September 15, 2020",Severe Acute Respiratory Syndrome Coronavirus 2,"Randomized,Parallel Assignment,This is a randomized, double-blind placebo-controlled Phase 1 single-dose dose-escalation study to assess the safety, tolerability and PK of oral inhalation of AHCQ in healthy participants.
A sentinel dose strategy will be employed and the decision to escalate to the next dose level, or deescalate or stop the study, will be based on review and analysis of all available blinded safety and tolerability data by the Safety Review Committee (SRC), which will make a recommendation to the Sponsor and the Sponsor will inform the PI of the recommendation.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,12
NCT04527432,Not yet recruiting,"November 1, 2020","December 31, 2020","Coronavirus Infection,Severe Acute Respiratory Syndrome","N/A,Single Group Assignment,Health Services Research,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,3000
NCT04371328,"Active, not recruiting","March 13, 2020",March 2021,Emergencies,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:15 Years,Max Age:N/A",No,1860
NCT04307693,Terminated,"March 11, 2020","April 30, 2020",COVID-19,"Randomized,Parallel Assignment,Multicenter, open labelled, randomized clinical trial,Treatment,None (Open Label)","gender:All,Min Age:16 Years,Max Age:99 Years",No,65
NCT04328480,Recruiting,"April 17, 2020","August 30, 2020",COVID-19,"Randomized,Parallel Assignment,Simple pragmatic randomized open controlled trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,2500
NCT04343768,Completed,"April 9, 2020","April 27, 2020",COVID-19,"Randomized,Parallel Assignment,The present study is a randomized clinical trial, with the approval of the ethics committee will be conducted on patients who have a positive test confirming COVID-19 in Loghman Hakim Medical Education Center in Tehran. Patients will be randomly assigned to the three arms of the study.
Patients will be allocated to three therapeutic arms (Hydroxychloroquine + Lopinavir / Ritonavir + Interferon-β 1a group and Hydroxychloroquine + Lopinavir / Ritonavir + Interferon-β 1b group and the Base Therapeutic Regiment Group, i.e., Hydropinchloroquine + / Ritonavir. For this purpose, we will use the method of Balance Block Randomization for three groups.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04340219,Completed,"March 30, 2020","September 18, 2020",Cancer,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,394
NCT04454372,Not yet recruiting,"July 15, 2020","November 30, 2020",COVID-19,"Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:1 Year,Max Age:N/A",No,187
NCT04337489,Not yet recruiting,"July 28, 2020","April 1, 2021",Coronavirus,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:95 Years",No,200
NCT04548505,Not yet recruiting,September 2020,March 2023,SARS-CoV Infection,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04447534,Recruiting,"June 23, 2020","October 1, 2020",COVID,"Randomized,Parallel Assignment,Treatment,Double (Participant, Care Provider)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04397835,Recruiting,"April 17, 2020","April 20, 2021","COVID-19,Anxiety,Depression,Stress","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:50 Years,Max Age:89 Years",No,800
NCT04428073,Not yet recruiting,July 2020,December 2021,COVID,"Non-Randomized,Sequential Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:60 Years",No,32
NCT04375098,Completed,"May 4, 2020","August 17, 2020",Severe Acute Respiratory Syndrome Coronavirus 2,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,58
NCT04358614,Completed,"March 16, 2020","April 7, 2020","COVID,Pneumonia","Non-Randomized,Crossover Assignment,Baricitinib treated patients compared with controls (previously COVID-19 receving standard therapy),Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:85 Years",No,12
NCT04569266,Recruiting,"August 7, 2020","May 7, 2022",Dyspnea,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04467918,Recruiting,"July 6, 2020","October 31, 2020",SARS-CoV2,"Randomized,Parallel Assignment,A total of 100 patients with SARS-CoV-2 infection will be included in the study (i.e., 50 cases in the CBD group plus pharmacological and clinical measures and 50 in the placebo group plus pharmacological and clinical measures). All patients will receive the clinical and pharmacological measures standardized by the Brazilian Ministry of Health's practical guidelines for diagnosis and treatment for mild and moderate cases for SARS-CoV-2,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04460599,Recruiting,"March 8, 2020","September 30, 2020",Encephalitis,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04487665,Not yet recruiting,"September 15, 2020","December 15, 2020",Covid19,"Ecologic or Community,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:40 Years",No,50
NCT04373486,Recruiting,"March 3, 2020","May 1, 2020",Covid-19 With Positive RT-PCR,"Case-Only,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,160
NCT04263402,Recruiting,"February 1, 2020","July 1, 2020",2019-nCoV Severe Pneumonia,"Randomized,Parallel Assignment,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04570202,Not yet recruiting,"October 15, 2020","July 15, 2022","Depression,Burnout, Professional,Post Traumatic Stress Disorder","Randomized,Parallel Assignment,Trials Within Cohort (TWIC) :
Participants are included within a cohort. They are screened using an online self-administered questionnaire for psychological distress (Post-Traumatic Stress Disorder, Burnout, Depression) every three months for one year.
People who are positive after screening (at M0 or M3 or M6) will be eligible for the trial and some of them will be randomly assigned to the treatment group. The rest of the cohort will be the second arm (control group).,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,900
NCT04412239,Recruiting,"April 20, 2020","September 20, 2020","TB - Tuberculosis,Patient Satisfaction","N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04441996,Enrolling by invitation,"July 17, 2020",October 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04465474,Recruiting,"May 1, 2020","December 31, 2022",COVID-19,"Other,Other","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:N/A",No,3000
NCT04351919,Withdrawn,"May 5, 2020","July 15, 2020",Patients With COVID19,"N/A,Single Group Assignment,open, interventional, multicentric study,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,0
NCT04334512,Recruiting,"June 22, 2020",September 2021,"COVID-19,Corona Virus Infection,Coronavirus-19,Sars-CoV2","Randomized,Parallel Assignment,This is a Randomized, Double-Blind, Placebo-Controlled Phase II interventional Study,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,600
NCT04306705,Recruiting,"February 20, 2020","June 20, 2020","Covid-19,SARS,Cytokine Storm,Cytokine Release Syndrome,Tocilizumab","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,120
NCT04452435,Recruiting,"July 21, 2020",September 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:70 Years",No,100
NCT04374552,Not yet recruiting,"May 5, 2020",April 2021,SARS-CoV-2 Infection,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Study medication will be tablets containing either active drug or placebo","gender:All,Min Age:20 Years,Max Age:N/A",No,140
NCT04474288,Recruiting,"July 16, 2020",July 2021,Covid19 Immunology,"Case-Control,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04448704,Recruiting,"June 22, 2020","December 31, 2020",Mental Health Issue,"Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:21 Years,Max Age:N/A",No,1000
NCT04425889,Completed,"May 5, 2020","June 1, 2020","COVID-19,SARS-CoV 2","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:99 Years",No,156
NCT04434248,"Active, not recruiting","April 23, 2020",July 2020,COVID-19,"Randomized,Sequential Assignment,This is an adaptive, multicenter, open-label, randomized clinical study of Favipiravir versus standard of care (SOC) in hospitalized patients with moderate to severe COVID-19 pneumonia.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,330
NCT04493294,Not yet recruiting,November 2020,December 2021,COVID-19 Pneumonitis,"N/A,Single Group Assignment,Using low dose whole lung radiotherapy to older patients who develop COVID-19 pneumonitis to improve their survival compared to historical data,Treatment,None (Open Label)","gender:All,Min Age:65 Years,Max Age:N/A",No,500
NCT04346186,Enrolling by invitation,"April 15, 2020","August 1, 2021",COVID,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,30000
NCT04542122,Not yet recruiting,"September 3, 2020","August 2, 2021",Morals,"Randomized,Crossover Assignment,Other,Triple (Participant, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:99 Years",No,500
NCT04476914,Recruiting,"June 29, 2020","December 31, 2020","Respiratory Failure,SARS-CoV 2,Corona Virus Infection,Post Intensive Care Unit Syndrome,Family Members,Post Traumatic Stress Disorder,Anxiety,Depression","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,250
NCT04339660,Recruiting,"February 1, 2020","June 30, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:75 Years",No,30
NCT04374084,Recruiting,"May 10, 2020",December 2021,"COVID-19,Convalescence","Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:70 Years",No,60
NCT04566770,Recruiting,"September 24, 2020","October 20, 2022",COVID-19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:6 Years,Max Age:N/A",No,481
NCT04408209,Recruiting,"April 23, 2020","September 15, 2021",COVID-19 Infection,"N/A,Single Group Assignment,Single arm,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04420286,Recruiting,"May 6, 2020","June 5, 2020","Coronavirus Infections,COVID19 Outbreak in France","Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,9000
NCT04445870,Recruiting,"May 1, 2020",December 2020,Cancer,"Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04390516,Completed,"March 24, 2020","May 30, 2020","COVID-19,Coronavirus,Mortality,Mechanical Ventilation","N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,197
NCT04453748,Enrolling by invitation,"June 8, 2020","November 30, 2021","COVID-19,Coronavirus Infection,Sars-CoV2,Complications","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:120 Years",No,200
NCT04513184,Recruiting,August 2020,"December 31, 2020",Covid19,"Randomized,Parallel Assignment,Multicenter, randomized, controlled trial adult patients with confirmed COVID-19 infection,Treatment,Double (Participant, Care Provider)","gender:All,Min Age:18 Years,Max Age:75 Years",No,60
NCT04530500,Enrolling by invitation,"August 13, 2020","August 31, 2021","Covid19,Androgen Receptor Gene Overexpression","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:Male,Min Age:18 Years,Max Age:90 Years",No,200
NCT04516512,Not yet recruiting,"September 1, 2020","January 1, 2021",COVID-19,"N/A,Single Group Assignment,Screening,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,2500
NCT04346043,Not yet recruiting,"April 20, 2020","December 1, 2020",Coronavirus Disease (COVID-19),"Case-Only,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,100
NCT04367896,Completed,"March 24, 2020","April 17, 2020",COVID-19 OUTBREAK AND SOLID ORGAN TRANSPLANTATION,"Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1819
NCT04346602,Recruiting,"February 1, 2020","December 1, 2020",COVID-2019,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:1 Year,Max Age:80 Years",No,132
NCT04406532,Not yet recruiting,"October 20, 2020","March 1, 2021",Covid-19,"Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04393142,Recruiting,"May 5, 2020","June 15, 2020",Coronavirus Infection,"Other,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:1 Year,Max Age:N/A",No,92
NCT04363827,Recruiting,"May 14, 2020",March 2021,"COVID19,Hydroxychloroquine,Prophylaxis,Treatment,SARS-CoV-2","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,2300
NCT04328961,"Active, not recruiting","March 31, 2020","October 31, 2020","COVID-19,Corona Virus Infection,SARS (Severe Acute Respiratory Syndrome),SARS-CoV-2","Randomized,Parallel Assignment,Prevention,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:80 Years",No,829
NCT04348383,Recruiting,"April 8, 2020","January 15, 2021",COVID19,"Randomized,Parallel Assignment,Phase IIb prospective, multi-center, randomized, parallel, double blind, placebo controlled,Treatment,Double (Participant, Investigator),double blind","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04366986,Recruiting,"June 23, 2020","April 30, 2024",Covid-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:N/A",No,25000
NCT04465981,Recruiting,July 2020,June 2021,"COVID-19,Corona Virus Infection","Cohort,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04407286,Recruiting,"May 19, 2020","May 18, 2021","Covid 19,Vitamin D Deficiency","N/A,Single Group Assignment,This is an open label treatment study for people with COVID 19 and low levels of vitamin D,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04424849,Recruiting,"March 15, 2020","July 15, 2020",COVID-19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04392323,Recruiting,"May 13, 2020","July 31, 2020",Sars-CoV2,"N/A,Single Group Assignment,Prospective Cohort,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04407299,Completed,"April 20, 2020","May 20, 2020",COVID,"Other,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:16 Years,Max Age:N/A",No,360
NCT04515225,Not yet recruiting,"September 15, 2020","September 15, 2020",HIV Infections,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04359849,Recruiting,May 2020,September 2022,Coronavirus Infection,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:7 Years,Max Age:N/A",No,500
NCT04427098,Recruiting,"May 22, 2020","October 30, 2020",COVID-19,"Non-Randomized,Parallel Assignment,The study consists of two parts:
a phase II single-arm interventional prospective study including all patients treated with the study drug;
an observational prospective cohort study including all patients screened for receiving the study drug but not included in the phase II study.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:90 Years",No,300
NCT04381923,Not yet recruiting,"August 15, 2020","May 15, 2021","Severe Acute Respiratory Syndrome Coronavirus 2,Hypoxemic Respiratory Failure,Pneumonia, Viral,COVID","Randomized,Crossover Assignment,This will be a randomized study with alternating treatment assignment in which all advanced respiratory units will be assigned to use one of two default interventions (helmet CPAP vs HFNO) as the first-line treatment for refractory hypoxemia (defined as an oxygen saturation (Sp02) of 92% or less on on ≥ 6 LPM (liters per minute) nasal cannula (NC) oxygen). The first-line treatment will be alternated in each unit at 14-day intervals. The initial assignment will be determined by a computer randomization scheme. Patients who are still on their assigned intervention during crossover will remain on that assigned intervention. A design with numerous short periods and frequent crossovers was selected to minimize the risk of changes over time in the patient population and usual care confounding trial results. A 14-day period is also felt to be the minimal time needed to ensure device availability and adherence.,Supportive Care,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04443803,Not yet recruiting,"July 1, 2020","August 31, 2020",COVID-19,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:120 Years",No,9
NCT04356508,Not yet recruiting,"April 14, 2020","August 31, 2021","COVID-19,SARS-CoV-2,2019-nCoV,Pneumonia, Viral","Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,15
NCT04468009,Recruiting,"June 25, 2020",June 2021,"SARS-Associated Coronavirus,Covid19,SARS-CoV Infection","Randomized,Sequential Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:100 Years",No,36
NCT04340050,"Active, not recruiting","April 10, 2020","December 31, 2021",Coronavirus,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,10
NCT04422340,Recruiting,"April 1, 2020","August 15, 2020","COVID-19 Disease, Severe Form","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:60 Years,Max Age:N/A",No,185
NCT04357041,"Active, not recruiting","April 17, 2020",April 2021,"ALL, Adult","Case-Only,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04558320,Recruiting,"July 2, 2020","April 1, 2021",Coronavirus Infection,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04379271,Recruiting,"June 11, 2020",October 2020,COVID-19,"Randomized,Parallel Assignment,double-blind, placebo-controlled, randomized, parallel-group trial,Treatment,Double (Participant, Investigator),Trial participants, the investigator and all other personnel directly involved in the conduct of the trial will be blinded to treatment assignments.
To maintain the blind, IMU-838 and placebo tablets will have identical appearance, shape and color, and will have identical labeling and packaging. To minimize the potential for bias, treatment randomization information will be kept confidential by the responsible personnel and will not be released to investigators, other trial center personnel, or the Sponsor's designee(s).","gender:All,Min Age:18 Years,Max Age:N/A",No,230
NCT04352985,Available,N/A,N/A,N/A,N/A,"gender:All,Min Age:18 Years,Max Age:N/A",N/A,N/A
NCT04576728,Not yet recruiting,October 2020,March 2021,Covid19,"Randomized,Parallel Assignment,Subjects will be randomized on a 1:1 basis either to trimodulin or to placebo treatment stratified by center.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),All bottles will be indistinguishable.","gender:All,Min Age:18 Years,Max Age:N/A",No,164
NCT04468087,Not yet recruiting,"October 7, 2020","December 31, 2021",COVID-19,"Randomized,Parallel Assignment,Randomized, double-blinded, multicenter, multi-arm, multi-stage, study. COVID-19 confirmed by reverse-transcriptase-polymerase-chain-reaction (RT-PCR) hospitalized patients with ≤ 7 days duration of symptoms will be randomly assigned to receive antivirals with potential effectiveness for SARS-CoV-2.
The study is planned to be an adaptive phase II / III study. The phase II will be divided into 2 stages: first and second stages. First stage will allocate patients into a 5:5:5:5:5:1:1:1:1:1:1 allocation ratio (5 for each treatment group and 1 for placebo) and second stage will allocate into 2:2:1:1 (2 for each treatment group and 1 for placebo). The phase 3 study will then proceed in a 2:1 allocation (2 treatments for each placebo).,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),This is a double-blind study for participants of the same active drug and researchers. Both participant and investigator can know, after randomization, which medication they were allocated to. However, none will know whether the capsule to be administered is active or placebo, ensuring blinding within that specific group to which the participant was allocated.","gender:All,Min Age:18 Years,Max Age:90 Years",No,1134
NCT04501965,Enrolling by invitation,"June 1, 2020","September 30, 2020",Covid19,"Randomized,Parallel Assignment,Eligible consenting symptom-free patients with COVID-19 confirmed by a positive Polymerase Chain Reaction test were subjected to the 10 days of treatment allocated to each of the 3 arms of the trial. Virological clearance is assessed on days 3, 6 and 14. Side effects are noted throughout the trial period. Clinical, paraclinical and laboratory examinations are occasionally provided. Viral clearance, side effects, and the onset of COVID symptoms are evaluated and the data is statistically processed.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,231
NCT04497246,Recruiting,"May 29, 2020",December 2020,Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,5000
NCT04371471,Completed,"March 1, 2020","April 30, 2020","Sars-CoV2,Covid19","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04437693,Not yet recruiting,"August 31, 2020","December 31, 2021",COVID 19,"Randomized,Parallel Assignment,An interventional, double-blind, placebo-controlled randomized trial,Prevention,Single (Participant),The process of keeping the study group assignment hidden after allocation will be used where the investigator and participants will be unaware of the drug.A double blind randomized clinical trial has been proposed having 250 subjects in each arm. 500 subjects will be selected using randomly permuted blocks of 2,4, and 8 for the random process to allocate subjects into the two groups equally by using computer software.","gender:All,Min Age:18 Years,Max Age:60 Years",No,500
NCT04548557,Not yet recruiting,"September 15, 2020","November 15, 2020",Covid19,"Randomized,Parallel Assignment,one group in conventional with routine therapy and interventional group will receive intravenous immunoglobulin therapy,Treatment,Double (Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:90 Years",No,60
NCT04339426,Recruiting,"April 20, 2020",April 2021,Covid19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:95 Years",No,25
NCT04407546,Recruiting,"May 27, 2020","May 28, 2023",Immunosuppression,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,300
NCT04338906,Not yet recruiting,"June 1, 2020","December 31, 2021",COVID,"Randomized,Parallel Assignment,Evaluation of the efficacy and safety of hydroxychloroquine + camostat combination therapy in comparison to hydroxychloroquine + placebo in hospitalized patients with moderate COVID-19 infection, CLOCC-Trial,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,334
NCT04322773,Recruiting,"April 5, 2020","June 1, 2021",Corona Virus Disease,"Randomized,Sequential Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04513561,Not yet recruiting,December 2020,March 2021,"Inflammatory Disease,Covid19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,4500
NCT04392128,Withdrawn,"September 2, 2020","September 2, 2020","COVID19,Hematologic Malignancy","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04399967,Recruiting,"June 13, 2020","June 30, 2022",Smoking Cessation,"Randomized,Parallel Assignment,Health Services Research,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,842
NCT04233268,Recruiting,"April 6, 2020","February 28, 2025","Lower Respiratory Tract Infection,Ventilator Associated Pneumonia,COVID19","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:16 Years",No,250
NCT04546581,Not yet recruiting,September 2020,July 2021,"COVID,COVID-19,SARS-CoV-2,SARS (Severe Acute Respiratory Syndrome)","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04490473,Recruiting,"July 24, 2020","December 24, 2020","Anxiety,SARS-CoV Infection","N/A,Single Group Assignment,This research will be conducted in a methodological manner in order to conduct the validity and reliability studies of the Coronary Virus Anxiety Scale in Turkish.,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:60 Years",No,300
NCT04371952,Not yet recruiting,"June 1, 2020","December 1, 2020",COVID19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator),Double blind","gender:All,Min Age:46 Years,Max Age:N/A",No,330
NCT04528329,Recruiting,"August 30, 2020","December 15, 2020","Covid19,Anosmia","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04259892,Recruiting,"February 4, 2020","February 4, 2021",Coronavirus,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,345
NCT04371744,Completed,"April 17, 2020","June 5, 2020",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04352751,Recruiting,"May 1, 2020",April 2021,Covid-19,"N/A,Single Group Assignment,Single arm, open label, clinical trial employing WHO recognized monitored emergency use of unregistered and experimental interventions (MEURI) study.,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:55 Years",No,2000
NCT04374474,Withdrawn,"January 10, 2021","March 10, 2022",Olfactory Disorder,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04390165,Not yet recruiting,May 2020,August 2020,"SARS-CoV Infection,COVID-19,Anosmia,Dysgeusia","Case-Only,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,760
NCT04378829,Recruiting,"September 12, 2020","October 21, 2020","Covid-19,Mean Platelet Volume,Platelet Destruction","Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,40
NCT04341415,Recruiting,"April 9, 2020",March 2021,"Covid19,SARS-CoV Infection","Randomized,Parallel Assignment,Treatment,Double (Participant, Care Provider),The participants and the care providers will not know the arm of randomization. Only the principal investigator who will perform the intervention will know the type of intervention.","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04441684,Recruiting,"April 17, 2020",August 2021,"SARS-CoV-2 Serological Status,SARS-CoV-2 Seroprevalence","Non-Randomized,Parallel Assignment,Screening,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,1800
NCT04559009,Not yet recruiting,"October 15, 2020","April 30, 2024","Covid19,Amyotrophic Lateral Sclerosis","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04470648,Not yet recruiting,July 2020,November 2020,SARS-COV2 Infection,"Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,220
NCT04264533,Recruiting,"February 14, 2020","September 30, 2020","Vitamin C,Pneumonia, Viral,Pneumonia, Ventilator-Associated","Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,140
NCT04380727,Completed,"March 20, 2020","April 25, 2020","COVID-19,Hypoxic Respiratory Failure","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,17
NCT04524052,Not yet recruiting,August 2020,December 2020,Healthy,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:45 Years",No,32
NCT04576312,Recruiting,"June 29, 2020","December 31, 2020",COVID-19,"Randomized,Sequential Assignment,Other,Single (Investigator)","gender:All,Min Age:18 Years,Max Age:65 Years",No,44
NCT04382066,Recruiting,"May 12, 2020",November 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,27
NCT04405570,Recruiting,"June 16, 2020","November 15, 2020",SARS-CoV 2,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,108
NCT04389801,Not yet recruiting,"June 1, 2020","December 31, 2020",Covid 19,"Randomized,Parallel Assignment,Desferal group An initial dose of 1000 mg should be administered at a rate NOT TO EXCEED 15 mg/kg/hr. This may be followed by 500 mg over 4 hours for two doses. Depending upon the clinical response, subsequent doses of 500 mg may be administered over 4-12 hours.,Treatment,Single (Participant),Placebo group Will receive glucose 5% over 4 hrs infusion","gender:All,Min Age:N/A,Max Age:N/A",No,200
NCT04351529,Recruiting,"April 1, 2020",December 2021,"Infectious Disease,COVID-19","Other,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04334967,Suspended,"March 30, 2020","May 27, 2022","COVID-19,Corona Virus Infection,SARS-CoV-2,2019-nCoV,2019 Novel Coronavirus","Randomized,Parallel Assignment,Upon confirmation of positive nasopharyngeal test for SARS-CoV-2, eligible patients will be randomized 1:1 to either a treatment group or control group.,Treatment,Single (Outcomes Assessor),Analysts will be blinded to patient randomization; outcome data analyses will be conducted with patient identifiers removed.","gender:All,Min Age:45 Years,Max Age:N/A",No,13
NCT04389372,Recruiting,"March 15, 2020",December 2021,Migraine Headache,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:65 Years",No,50
NCT04456452,"Active, not recruiting","July 27, 2020","November 13, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:89 Years",No,10
NCT04363853,Recruiting,"June 1, 2020","August 1, 2021",Sars-CoV2,"N/A,Single Group Assignment,Phase II, single-arm, open-label, prospective, blinded, clinical trial with Tocilizumab as the sole agent.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:90 Years",No,200
NCT04408170,Recruiting,"June 19, 2020","May 31, 2021","Coronavirus Infection,COVID-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,1000
NCT04486313,Recruiting,"August 13, 2020","December 30, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:12 Years,Max Age:120 Years",No,800
NCT04358081,Completed,"May 1, 2020","July 27, 2020",Covid-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,20
NCT04351724,Recruiting,"April 16, 2020","December 31, 2020",COVID-19,"Randomized,Parallel Assignment,Three main study arms (antiviral treatments) and three substudies (A, B, C) are planned. The main study arms are exclusive, while patients from the main study arms may participate in one or more substudies.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:99 Years",No,500
NCT04342728,Enrolling by invitation,"April 8, 2020","April 30, 2021","COVID,Corona Virus Infection","Randomized,Single Group Assignment,A single-center, prospective, open label four arm study (1. Zinc only 2. Zinc and ascorbic acid 3. Ascorbic acid only 4. Standard of care.,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,520
NCT04371679,Recruiting,"April 1, 2020","December 1, 2020",Covid-19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,40
NCT04459962,Recruiting,"June 29, 2020","June 14, 2021",Covid-19 Infection,"N/A,Single Group Assignment,Participants who are Covid-19 negative, Covid-19 positive or suspected with Covid-19 infection will be recruited,Diagnostic,None (Open Label)","gender:All,Min Age:16 Years,Max Age:N/A",No,250
NCT04346693,"Active, not recruiting","April 8, 2020",December 2020,"Acute Respiratory Tract Infection,Acute Respiratory Insufficiency,Pneumonia,Septic Shock,Hypoxemia","Randomized,Factorial Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,320
NCT04395391,Completed,"May 18, 2020","June 16, 2020",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04447833,Recruiting,"June 17, 2020","June 30, 2025","ARDS, Human,COVID","N/A,Single Group Assignment,This is an open label, dose escalating safety study of the advanced therapy investigational medicinal product (ATIMP) KI-MSC-PL-205, where patients diagnosed with SARS-CoV-2-induced severe acute respiratory distress syndrome (ARDS).,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:65 Years",No,9
NCT04323345,Recruiting,"April 15, 2020","January 15, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,Single (Investigator)","gender:All,Min Age:5 Years,Max Age:75 Years",No,1000
NCT04355494,Available,N/A,N/A,N/A,N/A,"gender:All,Min Age:18 Years,Max Age:N/A",N/A,N/A
NCT04365335,Completed,"April 25, 2020","June 12, 2020",Occupational Stress,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:60 Years",No,50
NCT04443725,Not yet recruiting,July 2020,December 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:65 Years",No,100
NCT04343781,Completed,"March 22, 2020","April 5, 2020","SARS-CoV-2,COVID-19","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:70 Years,Max Age:N/A",No,353
NCT04378842,Recruiting,"May 18, 2020",May 2021,"Sars-CoV2,Critical Illness","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,690
NCT04275947,Recruiting,"February 14, 2020","May 31, 2020",COVID-19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:90 Years",No,450
NCT04470557,Not yet recruiting,"July 15, 2020","December 1, 2020",COVID-19,"Other,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04510038,Not yet recruiting,"September 1, 2020","January 1, 2022","Covid19,Myocardial Injury","Randomized,Parallel Assignment,Active group (Colchicine plus standard of care) vs Control group (standard of care alone),Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:100 Years",No,75
NCT04393415,Recruiting,"May 25, 2020","September 1, 2020",Virus,"Randomized,Parallel Assignment,Supportive Care,Double (Participant, Outcomes Assessor)","gender:All,Min Age:20 Years,Max Age:70 Years",No,100
NCT04374123,Completed,"April 20, 2020","June 15, 2020",COVID,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,111
NCT04380779,Recruiting,"April 13, 2020","June 13, 2025",COVID-19,"Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,5000
NCT04433364,Recruiting,"June 2, 2020","June 2, 2041","Sars-CoV2,Covid-19,Pregnancy Complications,Pregnancy Preterm,Pregnancy in Diabetic,Neonatal Infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:N/A",No,1200
NCT04401254,Not yet recruiting,July 2020,April 2022,"COVID-19,Critical Illness","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04330521,Recruiting,"April 8, 2020",May 2022,"Cancer,COVID-19","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:99 Years",No,50
NCT04552951,Recruiting,"April 4, 2020","December 30, 2020",COVID-19,"Randomized,Parallel Assignment,Patients receiving any form. of vitamin D excluded from the study. Randomized study (Initial serum calcidiol levels blinded ),Treatment,Double (Participant, Outcomes Assessor)","gender:All,Min Age:N/A,Max Age:N/A",No,80
NCT04440098,Completed,"April 22, 2020","May 11, 2020","Loneliness,Depression,Anxiety,Alcohol Abuse,Drug Abuse","Case-Only,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:35 Years",No,1008
NCT04338009,Enrolling by invitation,"March 31, 2020","December 31, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:N/A",No,152
NCT04532372,Not yet recruiting,"September 18, 2020","September 18, 2022","Hematopoietic and Lymphoid Cell Neoplasm,Malignant Solid Neoplasm,Symptomatic COVID-19 Infection Laboratory-Confirmed","Randomized,Sequential Assignment,Phase I single-arm dose-escalation design followed by a phase II randomized two-arm design,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,30
NCT04365439,Not yet recruiting,"April 27, 2020","June 30, 2020","Blood Plasma Therapy,COVID","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,10
NCT04488081,Recruiting,"July 31, 2020","November 1, 2022",COVID-19,"Randomized,Parallel Assignment,Platform Trial, Bayesian Design,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,1500
NCT04306055,Completed,"March 13, 2020","April 3, 2020",Blood Donation,"Randomized,Parallel Assignment,Health Services Research,None (Open Label)","gender:All,Min Age:18 Years,Max Age:60 Years",No,19491
NCT04381884,Completed,"May 18, 2020","September 29, 2020",COVID-19 Drug Treatment,"Randomized,Parallel Assignment,Patients will be randomized to receive Ivermectin 600 µg / kg / once daily plus standard care or standard care upon diagnosis of COVID-19.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:69 Years",No,45
NCT04393402,Recruiting,"March 20, 2020","December 31, 2020",COVID,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:95 Years",No,14
NCT04558125,"Active, not recruiting","September 8, 2020","June 30, 2022","Pulmonary Embolism,COVID","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:75 Years",No,45
NCT04497454,Recruiting,"May 8, 2020","December 1, 2021","Respiratory Distress Syndrome,Severe Acute Respiratory Syndrome Due to Coronavirus (SARS-CoV2),Mechanical Ventilation","Randomized,Parallel Assignment,Prospective, randomized, single-center, open-label, superiority, controlled trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,128
NCT04385095,Recruiting,"March 16, 2020","May 31, 2021",SARS-CoV-2,"Randomized,Parallel Assignment,Randomised double-blind placebo-controlled
Pilot phase - 100 patients randomised in the hospital setting, 120 patients randomised in the home setting.
Pivotal phase - estimated at an additional 100 to 300 patients per arm, but the actual number will be determined after the data review at the end of the Pilot phase,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double-blind","gender:All,Min Age:18 Years,Max Age:N/A",No,820
NCT04376658,Not yet recruiting,"June 15, 2020","September 15, 2021","Quality of Life,Long-term Outcomes,Coronavirus Infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04469114,Recruiting,"September 16, 2020","January 31, 2021",Covid19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,260
NCT04416113,Not yet recruiting,August 2020,February 2021,Photodynamic Therapy& Low Level Laser in Management of COVID 19,"Randomized,Parallel Assignment,A randomized controlled study will be conducted on 60 patients of positive COVID 19. The patients will be divided into 3 equal groups. Group I will receive low level laser (diode laser 980nm) from laser watch for 30 minutes, 20 J for 3 to 5 days and laser acupuncture. Group 2 will be treated with photodynamic therapy by injecting the methylene blue as a photosensitizer and irradiated with laser watch (diode laser 670 nm). Group 3 will serve as a control. Evaluation methods will include laboratory investigations and CT chest.,Treatment,Single (Participant)","gender:All,Min Age:N/A,Max Age:N/A",No,60
NCT04382547,Enrolling by invitation,"May 11, 2020","June 30, 2021","COVID,Covid-19,Coronavirus,Pneumonia,Pneumonia, Viral,Pneumonia, Interstitial,Sars-CoV2","Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,40
NCT04472585,Recruiting,"July 14, 2020","September 30, 2020","Coronavirus Infection,COVID,Sars-CoV2","Randomized,Parallel Assignment,randomized, controlled, multi-armed, open-label, interventional study,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Empty capsule will sub-cutaneous injection of ivermectin will be used","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04391946,Recruiting,"March 14, 2020","December 31, 2022","Chronic Lymphocytic Leukemia, Lymphocytic Lymphoma or Waldenstrom Disease","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04531501,Recruiting,"June 29, 2020","September 29, 2020",Covid19,"Cohort,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:117 Years",No,400
NCT04463823,Not yet recruiting,"July 6, 2020","May 31, 2025",COVID,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04338841,Completed,"April 9, 2020","June 17, 2020",Coronavirus Infection,"Non-Randomized,Sequential Assignment,Quasi-experimental before and after multicentre prospective study,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,3133
NCT04380987,Recruiting,"May 4, 2020","December 31, 2021",Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04428008,Not yet recruiting,September 2020,August 2021,COVID-19,"Randomized,Parallel Assignment,Subjects will be centrally randomized to receive either study treatment drug (Ta1) or no Ta1. Randomization will be stratified by site.,Prevention,None (Open Label)","gender:All,Min Age:60 Years,Max Age:N/A",N/A,240
NCT04359511,Not yet recruiting,June 2020,December 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,210
NCT04557241,Not yet recruiting,October 2020,February 2021,COVID19 Behavioral Prophylaxis,"Randomized,Parallel Assignment,Prevention,Double (Participant, Outcomes Assessor),Although this is, in practice, a double-blind study since participants will be unaware that they are randomized and all study mechanics will be processed by computer, analysts will not be blinded to the meaning of the assignment variable. However, two independent consultant analysts have been retained to verify all results and subsequent interpretation.","gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04460690,Enrolling by invitation,"July 13, 2020",July 2021,"COVID-19,Sars-CoV2","N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:5 Years,Max Age:N/A",No,10000
NCT04573348,Not yet recruiting,"October 10, 2020","October 10, 2021","Covid19,Corona Virus Infection","Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04429711,Recruiting,"May 12, 2020","October 31, 2020",COVID-19,"Randomized,Parallel Assignment,Double blind randomized,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:80 Years",No,100
NCT04410562,Recruiting,"May 13, 2020","August 1, 2021","Pregnancy Related,COVID,Covid-19","Randomized,Parallel Assignment,Randomized, double-blinded, placebo-controlled multicentre clinical trial.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:Female,Min Age:N/A,Max Age:N/A",No,714
NCT04355429,Not yet recruiting,"May 5, 2020",August 2020,"Pneumonia,Coronavirus Infection,COVID-19","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,230
NCT04361474,Recruiting,"May 18, 2020","May 25, 2021","Budesonide,Olfaction Disorders,SARS-CoV-2,Anosmia","Randomized,Parallel Assignment,Patients with persistent hyposmia related to a SARS-CoV-2 infection,Treatment,Single (Participant),Patients with persistent hyposmia related to a SARS-CoV-2 infection","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04425850,"Active, not recruiting","June 1, 2020","August 10, 2020",Contagious Pleuropneumonia,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:5 Years,Max Age:N/A",No,70
NCT04395508,Available,N/A,N/A,N/A,N/A,"gender:All,Min Age:18 Years,Max Age:N/A",N/A,N/A
NCT04459676,Recruiting,"July 31, 2020",October 2020,"COVID-19,Pneumonia","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04412382,Recruiting,"June 1, 2020","December 31, 2021",Covid-19,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04393038,Recruiting,"May 1, 2020","April 30, 2021",COVID-19,"Randomized,Parallel Assignment,Phase 2/3, randomized, double blind, placebo-controlled study,Treatment,Triple (Participant, Care Provider, Investigator),Blinded treatment bottles","gender:All,Min Age:18 Years,Max Age:N/A",No,1034
NCT04556149,Recruiting,"October 1, 2020","December 31, 2020","Corona Virus Infection,Coronavirus","Case-Control,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:90 Years",No,30
NCT04444297,Not yet recruiting,"July 31, 2020","January 31, 2021","Telemedicine,Surgery, Plastic","Randomized,Crossover Assignment,Randomised to 2D then 3D, or 3D then 3D telemedicine consultations,Other,Double (Investigator, Outcomes Assessor),Investigator and outcomes assessor will be blinded to method of telemedicine. It is not possible to blind participants.","gender:All,Min Age:16 Years,Max Age:75 Years",No,40
NCT04348409,Recruiting,"May 25, 2020","July 31, 2020",COVID-19,"Randomized,Parallel Assignment,Patients will be randomized to receive either nitazoxanide or placebo (1:1).,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04433312,Not yet recruiting,"July 1, 2020","December 1, 2020","Satisfaction, Patient,Quality of Life","Other,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,10000
NCT04348929,Recruiting,"April 16, 2020","October 1, 2021",Postpartum Depression,"Non-Randomized,Parallel Assignment,Screening,None (Open Label)","gender:Female,Min Age:18 Years,Max Age:N/A",No,927
NCT04496128,Enrolling by invitation,"April 13, 2020","March 31, 2021","SARS-CoV 2,Neurologic Manifestations","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04392089,Recruiting,"May 1, 2020","May 1, 2021","COVID-19,Respiratory Failure","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04575571,Recruiting,"April 29, 2020","April 29, 2025",Psychosocial Impacts of the COVID-19 Pandemic,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:14 Years,Max Age:N/A",No,5000
NCT04418375,Not yet recruiting,June 2020,March 2022,COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,4000
NCT04334876,Not yet recruiting,"April 1, 2020","January 1, 2021",SARS-CoV-2,"Ecologic or Community,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,340
NCT04364711,Not yet recruiting,"May 1, 2020","April 30, 2022","COVID-19,SARS-CoV 2","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,2000
NCT04326920,Recruiting,"March 24, 2020","December 31, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,80
NCT04456439,Available,N/A,N/A,N/A,N/A,"gender:All,Min Age:2 Months,Max Age:17 Years",N/A,N/A
NCT04540939,Not yet recruiting,October 2020,December 2021,Trauma,"Randomized,Parallel Assignment,Treatment,Double (Investigator, Outcomes Assessor),Statistician will not know the group assignment until blind is broken. Statistician randomizes the groups. Principal investigator will not know group assignment until blind is broken.","gender:All,Min Age:18 Years,Max Age:72 Years",No,60
NCT04335162,Recruiting,"February 28, 2020","August 28, 2020","COVID,Acute Coronary Syndrome,Myocardial Infarction,Myocarditis,Venous Thromboembolism,Deep Vein Thrombosis,Pulmonary Embolism","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04504032,Recruiting,"September 2, 2020",December 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,600
NCT04530396,Recruiting,"September 7, 2020","May 1, 2021",Covid19 Prevention,"Randomized,Parallel Assignment,Randomized double-blind placebo-controlled,Prevention,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:111 Years",No,40000
NCT04357860,Not yet recruiting,"April 27, 2020","July 27, 2020","SARS-CoV 2,SARS","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,120
NCT04414098,Not yet recruiting,"June 1, 2020","September 15, 2020",COVID-19,"N/A,Single Group Assignment,Experimental, open-label, prospective, single center, add-on (added to the standard treatment) study, compared with an historical control arm.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04385147,Completed,"May 18, 2020","July 5, 2020","Cholangitis, Secondary Biliary,Cholangiocarcinoma,Obstructive Jaundice,Pancreas Cancer,COVID-19,SARS-CoV-2","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,670
NCT04534569,"Active, not recruiting","September 4, 2020","October 5, 2020","Covid19,Acute Respiratory Failure,Acute Respiratory Distress Syndrome","Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:70 Years",No,40
NCT04541472,Recruiting,"May 1, 2020","December 1, 2020",Dental Surgeon,"Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:16 Years,Max Age:N/A",No,1000
NCT04563442,Not yet recruiting,"October 15, 2020","February 25, 2023",Covid19,"Case-Crossover,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,200
NCT04414904,Not yet recruiting,"June 10, 2020","May 14, 2021","Infertility, Male,Testosterone Deficiency","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:Male,Min Age:18 Years,Max Age:50 Years",No,100
NCT04377334,Not yet recruiting,October 2020,July 2021,"ARDS,COVID-19","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04422574,Completed,"May 1, 2020","May 30, 2020",Covid 19,"Ecologic or Community,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,97
NCT04407689,Recruiting,"June 8, 2020","December 30, 2020","COVID-19,Lymphocytopenia","Randomized,Parallel Assignment,randomized controlled of treatment vs placebo,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double blind","gender:All,Min Age:25 Years,Max Age:80 Years",No,48
NCT04393948,Recruiting,June 2020,November 2020,SARS-CoV 2,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:40 Years,Max Age:N/A",No,48
NCT04337762,Recruiting,"April 6, 2020",July 2021,COVID-19,"Case-Control,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:110 Years",No,100000
NCT04342702,"Active, not recruiting","March 16, 2020",March 2021,"Follow-up,COVID-19,Infectious Diseases,Respiratory","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,504
NCT04534478,Not yet recruiting,"September 7, 2020","December 15, 2021",COVID-19 Pneumonia,"Randomized,Parallel Assignment,Parallel clinical trial with therapeutic intervention, randomized, open and controlled, of non-inferiority,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04437719,Recruiting,"June 29, 2020","December 31, 2021","Oncology,COVID-19","N/A,Single Group Assignment,As part of this research, the patient must complete questionnaires daily on the Obvio-19 application, one of 5 minutes.,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04458519,Recruiting,"July 16, 2020","December 31, 2020",COVID-19 Infection,"Randomized,Parallel Assignment,Single-blinded, randomized, prospective trial,Treatment,Double (Care Provider, Outcomes Assessor),Investigator responsible for product allocation and blinding is not in contact with study participant and will only be made aware of the process of their evolution in case of emergency.
Study personel in daily contact with the patient are unaware of the patient treatment assignement and are thus blinded.","gender:All,Min Age:18 Years,Max Age:59 Years",No,40
NCT04347889,Not yet recruiting,"April 20, 2020","December 30, 2020",Covid-19,"Randomized,Parallel Assignment,Open label, controlled, RCT,Prevention,Single (Outcomes Assessor),Outcomes assessors will be masked to study assignment","gender:All,Min Age:18 Years,Max Age:N/A",No,1212
NCT04343053,"Active, not recruiting","April 8, 2020","June 9, 2021",Severe Acute Respiratory Syndrome Coronavirus 2,"N/A,Single Group Assignment,Diagnostic,None (Open Label),Technicians performing assays will be blinded to stage of the infection and outcomes","gender:All,Min Age:18 Years,Max Age:N/A",No,54
NCT04261907,Not yet recruiting,"February 7, 2020","June 30, 2020",2019-nCoV,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,160
NCT04428021,Not yet recruiting,"June 15, 2020","December 15, 2021",COVID-19,"Randomized,Parallel Assignment,Three arms randomized trial, partially blinded,Treatment,Triple (Participant, Care Provider, Outcomes Assessor),Only the two experimental arms are masked. COVID-19 convalescent plasma (CP) and standard plasma (SP) will be masked and delivered to the wards in identical bags; a tag printed as ""PLASMA TRIAL"" will cover the actual name of the product","gender:All,Min Age:18 Years,Max Age:N/A",No,180
NCT04360863,Recruiting,"April 24, 2020","June 30, 2020",Smoking Cessation,"Other,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:25 Years",No,150
NCT04324021,Recruiting,"April 2, 2020",December 2020,SARS-CoV-2,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:30 Years,Max Age:79 Years",No,54
NCT04384900,Recruiting,"May 11, 2020",December 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04376398,Recruiting,"April 6, 2020","September 30, 2020",COVID-19,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:100 Years",No,200
NCT04357418,Completed,"April 1, 2020","June 30, 2020","Anxiety State,COVID-19,Isolation, Social,Health Personnel Attitude","Other,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,187
NCT04329650,Recruiting,"April 15, 2020","May 20, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04344379,Suspended,"April 17, 2020","July 15, 2020",SARS-CoV-2 Infection,"Randomized,Parallel Assignment,Prevention,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,122
NCT04351763,Recruiting,"April 27, 2020","April 10, 2021",COVID-19,"Randomized,Parallel Assignment,parallel group, randomized trial,Treatment,Single (Outcomes Assessor),Clinical events will be validated blindly by an independent clinical event committee (CEC) unaware of the treatment allocation.","gender:All,Min Age:18 Years,Max Age:99 Years",No,804
NCT04361123,Enrolling by invitation,"May 6, 2020",December 2021,"Coronavirus,COVID","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,450000
NCT04427137,Recruiting,"June 9, 2020",December 2022,Bipolar Depression,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04476823,Completed,"March 15, 2020","May 31, 2020",Clinical Practice During the COVID-19 Crisis,"Ecologic or Community,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,71
NCT04494867,Recruiting,"August 19, 2020",December 2020,Covid19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04351789,Recruiting,"May 1, 2020",April 2023,"COVID-19,Mental Health,Psychoeducation,Anxiety","Randomized,Parallel Assignment,Randomized 1:1 to either intervention group or control group,Prevention,Single (Outcomes Assessor),Due to the nature of the intervention, the RCT trial is not blinded, but the outcome measures are masked for health professionals and staff until the end of the study","gender:All,Min Age:18 Years,Max Age:N/A",No,66
NCT04425499,Not yet recruiting,June 2020,June 2020,"Advanced Suturing Skills,Surgical Education","Randomized,Parallel Assignment,Other,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04456088,Not yet recruiting,"July 15, 2020","December 15, 2020","COVID-19,SARS-CoV 2,Respiratory Disease,Pneumonia, Viral,Corona Virus Infection","Randomized,Parallel Assignment,This is a two phase study. The first 10 subjects will be treated with 80ppm NO; The remaining 40 subjects will be randomized in 1:1 ratio with subjects receiving 150 NO+SST or the SST alone.,Treatment,None (Open Label)","gender:All,Min Age:22 Years,Max Age:75 Years",No,50
NCT04388410,Recruiting,"August 25, 2020","December 31, 2020",COVID-19,"Randomized,Parallel Assignment,Randomized, double-blinded, multicenter, placebo-controlled study,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Encasement of plasma and saline bags with an identical material will be done in Blood bank","gender:All,Min Age:18 Years,Max Age:N/A",No,410
NCT04319445,Recruiting,"March 22, 2020",December 2020,"Migraine Disorders,Stress,Anxiety","N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,200
NCT04362358,Not yet recruiting,"May 1, 2020","October 1, 2021","Stress - Prevention of Sleep Disorders, PTSD and Depression","Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,120
NCT04373044,Recruiting,"May 1, 2020","May 1, 2022",Symptomatic COVID-19 Infection Laboratory-Confirmed,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,144
NCT04425317,Recruiting,"June 24, 2020","June 15, 2021","Infertility,COVID,IVF","N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:Female,Min Age:N/A,Max Age:45 Years",No,20
NCT04479202,Completed,"February 8, 2020","April 23, 2020","Berberine,COVID-19","Randomized,Parallel Assignment,Treatment,Double (Participant, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:80 Years",No,76
NCT04399356,Not yet recruiting,"October 12, 2020","February 12, 2021",COVID-19,"Randomized,Parallel Assignment,Double-blinded randomized controlled trial.,Treatment,Triple (Participant, Care Provider, Investigator),As all members of the Study Team will be blinded, Tufts Investigational Drug Services (IDS) will be unblinded and will dispense both the Niclosamide and placebo. The study intervention (Niclosamide) and placebo will be packaged and as indistinguishable as possible.","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04565080,Recruiting,"October 12, 2020","December 31, 2021","Parkinson's Disease,Functional Movement Disorders,COVID-19","Ecologic or Community,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04386564,"Active, not recruiting","May 15, 2020","November 15, 2020","COVID-19,Kidney Injury","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04371250,"Active, not recruiting","April 30, 2020","December 30, 2020","Resilience, Psychological,Loneliness,Youth,Surveys and Questionnaires","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:25 Years",No,800
NCT04476927,Not yet recruiting,"August 1, 2020","June 30, 2021",COVID-19,"N/A,Single Group Assignment,Total of 300 subjects - 200 suspected to COVID-19 and 100 healthy volunteers. all subjects will be undergo the DiaNose test.
For data analysis and algorithm building, subjects will be divided into one of the following study groups:
Group 1: Covid-19 infected suspected (up to 300 subjects)
Sub-Group A: Clinical symptomatic patients with positive Covid-19 test (positive PCR);
Sub-Group B: Asymptomatic patients with positive Covid-19 test (positive PCR)
Sub-Group C: Clinical symptomatic patients with negative Covid-19 test (negative PCR) Additional sub-groups may be added according to clinical symptoms.
Group 2: Healthy volunteers (up to 100 subjects),Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04391309,Not yet recruiting,July 2020,September 2021,SARS-CoV2,"Randomized,Parallel Assignment,Randomized, Double-Blind, Placebo-Controlled,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Placebo consists of identical-appearing diluent","gender:All,Min Age:18 Years,Max Age:N/A",Yes,300
NCT04472494,Not yet recruiting,"July 20, 2020","January 14, 2021","COVID-19,SARS-CoV-2","Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,129
NCT04295551,Not yet recruiting,"March 14, 2020","April 14, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:100 Years",No,80
NCT04467931,"Active, not recruiting","January 19, 2020","July 31, 2020","Hypertension,COVID","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,10000
NCT04370886,Completed,"April 30, 2020","May 10, 2020",Blood Donation,"Randomized,Parallel Assignment,Health Services Research,None (Open Label)","gender:All,Min Age:18 Years,Max Age:60 Years",No,456517
NCT04407130,Enrolling by invitation,"June 16, 2020",July 2020,COVID-19 Patients,"Randomized,Parallel Assignment,Randomized, Double-Blind, Placebo-Controlled Trial,Treatment,Double (Participant, Investigator)","gender:All,Min Age:40 Years,Max Age:65 Years",No,72
NCT04367857,Recruiting,"April 18, 2020",October 2021,"Covid-19,Coronavirus Infection,Coronavirus","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04492410,Recruiting,"July 21, 2020",March 2021,Cancer,"N/A,Single Group Assignment,Screening,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04370015,Not yet recruiting,"May 15, 2020","October 15, 2020","SARS-CoV-2,Healthcare Workers","Randomized,Parallel Assignment,parallel assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double blinding","gender:All,Min Age:18 Years,Max Age:60 Years",No,374
NCT04483752,Recruiting,"June 8, 2020","November 8, 2021",CoV2 SARS Pneumonia,"N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04465695,Recruiting,"July 14, 2020","September 30, 2021",COVID-19,"Randomized,Parallel Assignment,Open-label randomised controlled trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,81
NCT04411147,Recruiting,"June 17, 2020","December 31, 2027",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,900
NCT04402840,Recruiting,"April 24, 2020",December 2020,"Acute Respiratory Distress Syndrome,COVID-19","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,5
NCT04429555,Not yet recruiting,September 2020,"December 1, 2021","Pneumonia, Viral","Randomized,Parallel Assignment,Randomized, double-blind, placebo-controlled, parallel-group study.,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:80 Years",No,40
NCT04379154,Recruiting,"April 14, 2020","November 16, 2020",COVID-19,"N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04398290,Withdrawn,"December 1, 2020","July 15, 2021","COVID-19,Hypoxemia,Hypoxemic Respiratory Failure","Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04443257,Enrolling by invitation,"July 8, 2020","July 25, 2021",Sars-CoV2,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04340921,Recruiting,"May 14, 2020","November 10, 2021","Cardiovascular Disease Acute,Cardiomyopathies,COVID","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,140
NCT04327674,Recruiting,"March 14, 2020","May 15, 2020",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,375
NCT04425213,Completed,"May 12, 2020","May 26, 2020","COVID,Severe Acute Respiratory Syndrome,Obesity,Comorbidities and Coexisting Conditions","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,250
NCT04488575,Recruiting,"August 26, 2020","December 21, 2020",Covid19,"Randomized,Parallel Assignment,Patients will be randomized to either the active (EDP1815) or placebo group (1:1 randomization), in addition to standard of care. Dosing will be initiated on a twice daily regime for the first 3 days (6 doses) and then once daily for the remaining 11 days (14 days total treatment course).,Treatment,Triple (Participant, Investigator, Outcomes Assessor),Fully blinded to the participants, investigator, and sponsor","gender:All,Min Age:18 Years,Max Age:N/A",N/A,60
NCT04360876,Not yet recruiting,"September 1, 2020","January 30, 2021","COVID-19,ARDS","Randomized,Parallel Assignment,Single-center, Phase 2a, pragmatic, randomized, double-blinded, placebo-controlled,Treatment,Double (Participant, Care Provider),Participants confirmed to meet all eligibility criteria who have provided informed consent will be randomized 1:1 to dexamethasone versus placebo. A randomized group assignment will be provided to the investigator or research assistant. Randomization will be performed according to a central randomization scheme and will stratified by site in permuted blocks of varying size.","gender:All,Min Age:18 Years,Max Age:N/A",No,90
NCT04343690,Withdrawn,"March 27, 2020","May 1, 2020",COVID-19,"N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04296643,Not yet recruiting,"April 1, 2020","January 1, 2021","Coronavirus,N95,Medical Mask","Randomized,Parallel Assignment,Prevention,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,576
NCT04490239,Not yet recruiting,August 2020,September 2020,Covid19,"Sequential Assignment,This study will evaluate the acute and multi-day (14 days) tolerability of intranasally administered heparin. Two doses will be tested in the acute phase: 1000 U/day, then 2000 U/day. In the multi-day phase, the highest tolerated dose from the acute phase will be tested over a 14-day period of daily self-administration.,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:65 Years",No,6
NCT04445376,Completed,"July 3, 2020","October 3, 2020",Covid19,"Non-Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:75 Years",No,20
NCT04360980,Recruiting,"March 20, 2020","September 30, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04328285,"Active, not recruiting","April 14, 2020","November 30, 2020",COVID-19,"Randomized,Parallel Assignment,A randomized double-blind placebo-controlled clinical trial,Prevention,Triple (Participant, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,1200
NCT04394117,Recruiting,"June 19, 2020","April 30, 2021","SARS-Cov-2,COVID-19","Randomized,Parallel Assignment,CLARITY is a randomised control trial of two parallel groups;
Standard Care + Angiotensin Receptor Blocker (ARB)
Standard Care
Participants will be randomised in a 1:1 ratio. Randomisation will be stratified according to whether the participant is planned for hospital admission or home-based care.,Treatment,Single (Outcomes Assessor),Trial Statistician and sponsor staff will remain blinded to treatment allocation throughout the trial.","gender:All,Min Age:18 Years,Max Age:N/A",No,605
NCT04351152,Recruiting,"April 30, 2020",September 2020,Coronavirus Disease 2019 (COVID-19) Pneumonia,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator),Double-Blind","gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04501783,"Active, not recruiting","May 20, 2020",August 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:60 Years",No,168
NCT04541979,Recruiting,"June 4, 2020","December 1, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04366908,Not yet recruiting,"April 28, 2020","August 28, 2020","SARS-CoV 2,COVID19,SARS (Severe Acute Respiratory Syndrome),Cytokine Release Syndrome,Cytokine Storm","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:90 Years",No,1008
NCT04481360,Not yet recruiting,August 2020,September 2021,Coronavirus,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:99 Years",No,100
NCT04416360,Recruiting,"May 5, 2020",January 2021,"Autism Spectrum Disorder,Attention-deficit Hyperactivity Disorder","N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:6 Years,Max Age:17 Years",No,40
NCT04368676,Recruiting,"June 25, 2020","June 30, 2021","Job Stress,Workplace Stress,Compassion Fatigue,Psychological Trauma,Healthcare Workers,Healthcare Providers","Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor),Participants will be blinded to the treatment hypothesis wand the data analyst will be blinded to treatment allocation.","gender:All,Min Age:18 Years,Max Age:70 Years",No,60
NCT04474496,Enrolling by invitation,"July 27, 2020","November 1, 2020",COVID-19,"Other,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04423770,"Active, not recruiting","June 8, 2020","June 8, 2021",Severe Acute Respiratory Syndrome Coronavirus 2,"Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,4000
NCT04412304,Completed,"March 6, 2020","May 28, 2020","Covid-19,Thromboembolic Events,Bleeding","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,166
NCT04363060,Not yet recruiting,"April 30, 2020","July 30, 2020",COVID-19 Pneumonia,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:99 Years",No,104
NCT04510207,Recruiting,"July 16, 2020","September 16, 2021",COVID-19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,45000
NCT04409509,Recruiting,"July 1, 2020",December 2020,Coronavirus Disease 2019 (COVID-19),"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,124
NCT04347538,Recruiting,"May 1, 2020",June 2022,COVID 19,"Randomized,Parallel Assignment,Patients enrolled will be randomized to one of three treatment groups (1. control- no intervention, 2. intervention 1 - nasal saline irrigations BID, 3. intervention 2- nasal saline irrigations with ½ teaspoon surfactant (Johnson's baby shampoo) BID).,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,90
NCT04351516,Recruiting,"April 21, 2020","May 1, 2021","SARS-CoV 2,COVID-19","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:65 Years,Max Age:N/A",No,350
NCT04366765,Recruiting,"March 19, 2020","June 30, 2021","COVID-19,SARS-CoV 2","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1500
NCT04344561,Recruiting,"May 25, 2020","May 1, 2021","COVID,Hypoxic Respiratory Failure","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,70
NCT04405843,Recruiting,"July 14, 2020","December 14, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04425031,Recruiting,"August 25, 2020","March 1, 2024","Hypoxemic Respiratory Failure,Oxygen Toxicity","Randomized,Parallel Assignment,Prevention,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,780
NCT04355871,Completed,"March 18, 2020","April 17, 2020",Covid19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,4035
NCT04387955,Not yet recruiting,May 2020,June 2021,"COVID-19,Chilblains","N/A,Single Group Assignment,Prospective Cohort,Diagnostic,None (Open Label)","gender:All,Min Age:12 Years,Max Age:N/A",No,30
NCT04452604,Not yet recruiting,"August 1, 2020","December 1, 2023","Acute Myeloblastic Leukemia,Acute Lymphoblastic Leukemia,SARS-CoV-2","Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04344925,Recruiting,"April 18, 2020",December 2020,COVID-19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04397497,Not yet recruiting,"May 22, 2020","November 22, 2020","Covid-19,Acute Respiratory Failure,ARDS, Human,Sars-CoV2,Viral Pneumonia","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04541485,Not yet recruiting,"October 6, 2020","January 29, 2021",COVID-19 Patients,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:65 Years",No,40
NCT04570501,Not yet recruiting,November 2020,May 2021,Covid19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,160
NCT04505631,Recruiting,"June 10, 2020",June 2021,"Covid19,Dyspnea","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04466800,Recruiting,"July 30, 2020","August 13, 2021",COVID,"Randomized,Parallel Assignment,Multicenter, randomized, comparative, parallel-group trial,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,160
NCT04452669,Not yet recruiting,"August 15, 2020","February 1, 2021",COVID-19,"Randomized,Parallel Assignment,Double-blind, placebo controlled study comparing study treatment group to placebo controls who received SOC,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Placebo controlled","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04524754,Recruiting,"July 11, 2020","November 30, 2020",Anosmia,"Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,218
NCT04529447,Completed,"June 10, 2020","August 10, 2020",Covid19,"Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,485
NCT04395911,Recruiting,"September 10, 2020",December 2021,"AKI,ARDS,COVID","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,35
NCT04535154,"Active, not recruiting","March 31, 2020","June 1, 2022","Covid19,Lung Function Decreased","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,264
NCT04512027,Recruiting,"September 15, 2020","October 16, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:45 Years",No,10
NCT04333251,Not yet recruiting,"April 1, 2020","December 31, 2022","Pneumonia, Interstitial","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,115
NCT04419610,Not yet recruiting,September 2020,March 2021,COVID,"Randomized,Single Group Assignment,Health Services Research,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,60
NCT04432298,Recruiting,"June 20, 2020",January 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:40 Years,Max Age:85 Years",No,130
NCT04383587,Completed,"May 6, 2020","July 31, 2020","SARS-CoV 2,COVID-19","N/A,Single Group Assignment,Health Services Research,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04480112,Enrolling by invitation,"June 2, 2020",May 2021,"Memory Disorders,Alzheimer Disease,Mild Cognitive Impairment","Non-Randomized,Crossover Assignment,The investigators will employ an AB/BA crossover design (2-sequence, 2-period, 2-treatment design) where A will be the intervention phase and B will be the passive control phase. Each period will have a duration of 1 month. Assessment of the primary outcome will be done at the end of each period. Since this is a study of a behavioral intervention, 4-week washout period will suffice to observe an acute change in cognitive performance without significant carryover effects.
To avoid imbalance among groups, randomization will be stratified by cognitive syndrome diagnosis (healthy older adult, mild cognitive impairment and mild dementia). Participants will be randomized to the treatment sequences using a 1:1 allocation ratio.,Other,Single (Outcomes Assessor),Trial investigators and outcome assessors will be blind to the treatment randomization and allocation..","gender:All,Min Age:N/A,Max Age:N/A",No,150
NCT04513847,Not yet recruiting,"August 13, 2020","October 13, 2020","Psoriasis,Covid19","Case-Control,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1000
NCT04363866,Not yet recruiting,May 2020,June 2021,"COVID-19,SARS-CoV-2","Randomized,Parallel Assignment,Treatment,Single (Participant),While participants will be blinded to the study intervention, study staff will be aware of treatment assignment.","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04359602,Recruiting,"April 8, 2020","April 20, 2042",Recovered From COVID-19,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,10000
NCT04356833,Recruiting,"April 22, 2020","January 14, 2021",COVID,"Non-Randomized,Sequential Assignment,phase II, open label, single centre, uncontrolled, repeated dose, pilot trial,Treatment,None (Open Label)","gender:All,Min Age:16 Years,Max Age:70 Years",No,24
NCT04420299,Recruiting,"June 4, 2020","March 31, 2021",Covid-19,"Randomized,Parallel Assignment,randomized, single-blind, parallel control group,Treatment,Single (Participant),Subjects will be blinded to the dosing regimen (treatment dose or prophylactic dose).","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04530617,Not yet recruiting,September 2020,February 2021,"Covid19,Diabetes,Hypertension,Obesity","Randomized,Parallel Assignment,A randomized, placebo-controlled, parallel, multicenter, multi-arm, phase II trial of novel agents for treatment of high-risk COVID-19 positive outpatients. Subjects who meet the inclusion/exclusion criteria and have properly signed the informed consent will be randomized to the test group or placebo group in the ratio of 1:1:1:1.,Treatment,Triple (Participant, Care Provider, Investigator),The masking of the protocol will be maintained throughout the duration of the study. This will be done with the use of a matched placebo and a non-continuous coding (tablets in the case of camostat and tea bags/coffer for Artemisia) that has the same description and dose as the interventions so that both, the investigators and the patient does not know the treatment assignment.","gender:All,Min Age:18 Years,Max Age:N/A",No,360
NCT04387890,Not yet recruiting,"June 1, 2020","August 31, 2020","COVID-19,SARS-CoV 2,Health Personnel","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04383444,Recruiting,"July 7, 2020","August 1, 2023",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1050
NCT04487769,Recruiting,"June 1, 2020",October 2020,"Covid19,Ultrasound,ARDS","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT03963622,Not yet recruiting,July 2020,July 2022,ARDS,"Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,370
NCT04360707,Recruiting,"April 8, 2020","April 8, 2021",SARS-CoV-2,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:1 Year,Max Age:N/A",No,300
NCT04333654,Terminated,"April 12, 2020","May 26, 2020",Coronavirus Infection,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:80 Years",No,8
NCT04365257,Recruiting,"May 13, 2020",December 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:45 Years,Max Age:85 Years",No,220
NCT04364984,Recruiting,"April 1, 2020","August 1, 2021","Hypertension,COVID-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:90 Years",No,10
NCT04328012,Recruiting,"April 6, 2020","April 1, 2021",SARS-CoV-2 Infection,"Randomized,Parallel Assignment,randomized, double blind, placebo controlled clinical trial,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,4000
NCT04397575,Recruiting,"April 3, 2020","September 1, 2020","Cancer,COVID,Solid Tumor,Social Inequality,French National Cohort,Chemotherapy,Immunotherapy,Surgery,Radiotherapy","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04393051,Not yet recruiting,"May 20, 2020","July 30, 2020","Covid-19,SARS-CoV 2,SARS Pneumonia","Randomized,Parallel Assignment,Phase II randomized clinical trial to evaluate the efficacy and safety of baricitinib in patients with SARS-CoV2 pneumonia,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,126
NCT04375137,Recruiting,"April 20, 2020","September 30, 2020",Oxidative Stress,"Case-Control,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,90
NCT04483908,Recruiting,"April 10, 2020","May 30, 2022",COVID-19 Infection,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,550
NCT04444609,Recruiting,"June 18, 2020",June 2022,"COVID-19,SARS-CoV 2,ARDS, Human,Immune System Disorder","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:16 Years,Max Age:N/A",No,230
NCT04568018,Recruiting,"July 3, 2020",December 2021,ARDS Due to COVID-19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:75 Years",No,120
NCT04368390,Recruiting,"April 3, 2020",April 2021,Covid-19,"Case-Only,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04529421,Not yet recruiting,September 2020,December 2020,"Infection,Infection Control","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,70000
NCT04321928,Recruiting,"April 1, 2020","August 21, 2021","SARS-CoV-2,Coronavirus,COVID-19,2019-nCoV,2019nCoV","Randomized,Parallel Assignment,This is a randomized controlled, adaptive, two-arm, parallel trial. The target patient population consists of adults age above 60 years without confirmed COVID-19 infection or current hospitalization. The sample size calculation suggests that 7576 subjects (3788/ each arm) are required. The allocation ratio is 1:1. Eligible participants in the generalized health education intervention arm will receive healthy lifestyle advice according to World Health Organization (WHO) principles. On the personalized education arm, participants will receive detailed informative intervention regarding lifestyle changes based on their current habits.,Prevention,Double (Participant, Outcomes Assessor),Subjects will be blinded to knowledge of the details of differences between the interventions.
Everyone else (outcome assessors, caregivers and data analysts) will be blinded regarding the allocation.","gender:All,Min Age:60 Years,Max Age:N/A",No,7576
NCT04516928,Recruiting,"September 21, 2020","November 2, 2020","SARS-CoV Infection,Covid19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,950
NCT04404244,Recruiting,"January 1, 2020","June 1, 2021",Coronavirus COVID-19,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:18 Years",No,100
NCT04368832,"Active, not recruiting","April 25, 2020","September 30, 2021","Pregnancy Related,COVID","Other,Prospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:N/A",No,108
NCT04573322,Recruiting,"September 10, 2020","December 14, 2021",SARS-CoV-2 (Covid19),"Randomized,Parallel Assignment,Open-label, pharmacokinetic, pharmacodynamic, ascending dose, safety and tolerability lead-in Single-center, randomized, placebo-controlled, double-blind, adaptive, safety and efficacy pilot,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Lead-in: no masking. Randomized pilot: The participants, care providers, investigators, and outcomes assessors are masked. The pharmacist, unblinded clinical research associate, and unblinded study drug administrator are not masked.","gender:All,Min Age:18 Years,Max Age:N/A",No,224
NCT04456595,Recruiting,"July 21, 2020",October 2021,COVID-19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,8870
NCT04475575,Completed,"April 6, 2020","July 1, 2020","SARS-CoV Infection,Covid19","N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,222
NCT04362124,Not yet recruiting,April 2020,November 2021,COVID-19,"Randomized,Parallel Assignment,A multicenter, double-blind, randomized, phase III clinical trial, divided into two groups (vaccine and placebo) using a 1: 1 allocation ratio.
The treatment allocation will be performed according to random code.,Supportive Care,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double-blind trial. The blinding of the investigational vaccine will be maintained using an opaque label for the two products (vaccine and placebo).
The subjects, who collect the data (e.g., investigator and coordinator) and who evaluate the data (e.g., statistician) will be blinded. One or more pharmacists/vaccine administrators designated from the facility will not be blinded. These designated unblinded individuals will maintain the blindness of the investigational vaccine and will not be involved in evaluating the safety of the subjects.","gender:All,Min Age:18 Years,Max Age:65 Years",No,1000
NCT04477642,Withdrawn,August 2020,December 2020,COVID-19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04364022,Recruiting,"April 23, 2020",March 2021,Prevention of COVID-19,"Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:16 Years,Max Age:N/A",No,300
NCT04400799,Recruiting,"June 15, 2020","April 14, 2021","COVID-19,Pulmonary Embolism, Deep Vein Thrombosis","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:50 Years,Max Age:N/A",No,1000
NCT04377464,Not yet recruiting,"May 5, 2020","April 30, 2022","COVID-19,Quality of Life","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04374643,Recruiting,"April 1, 2020","November 1, 2020","Depression,COVID 19","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04384471,Enrolling by invitation,"April 29, 2020","January 1, 2021","Type1diabetes,Covid19","Case-Only,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:1 Year,Max Age:N/A",No,384
NCT04534595,Recruiting,"April 30, 2019",March 2021,COVID-19 Experience,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:4 Years,Max Age:13 Years",No,1500
NCT04359316,Not yet recruiting,"April 20, 2020","May 5, 2020",COVID-19,"Randomized,Parallel Assignment,The present study is a randomized, double-blind, placebo-controlled, clinical trial, with the approval of the ethics committee will be conducted on patients who have a positive test confirming COVID-19 in Shahid Modarres Medical Education Center and Hospital in Tehran. Patients will be randomly assigned to the two arms of the study and after completing the course of treatment and collecting and analyzing the necessary information from each patient, the results of the study will be published both on this site and in the form of an article in a reputable international journal.,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04395170,Not yet recruiting,September 2020,June 2021,Coronavirus Disease 2019 (COVID-19),"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,75
NCT04450004,"Active, not recruiting","July 10, 2020","April 30, 2021",SARS-CoV 2,"Randomized,Sequential Assignment,Prevention,None (Open Label),Partially-blinded","gender:All,Min Age:18 Years,Max Age:55 Years",No,180
NCT04359277,Terminated,"April 21, 2020","September 20, 2020",COVID-19,"Randomized,Parallel Assignment,The proposed study is designed as an open label randomized trial of patients hospitalized COVID-19 positive patients with an elevated D-dimer. Patients will be randomized to higher-dose (e.g. therapeutic) anticoagulation versus lower-dose (e.g. prophylactic) anticoagulation in 1:1 ratio.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,77
NCT04385771,Not yet recruiting,"June 1, 2020","October 31, 2021","Coronavirus Infection,COVID,SARS-CoV 2,Respiratory Failure,Cytokine Storm,Extracorporeal Membrane Oxygenation","Randomized,Parallel Assignment,randomized controlled trial examining COVID-patients requiring vv-ECMO therapy (+/- cytokine adsorption),Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:100 Years",No,80
NCT04403880,Recruiting,"May 13, 2020",August 2021,"SARS-CoV-2,COVID-19","Cohort,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,727
NCT04372082,Not yet recruiting,May 2020,May 2023,Sars-CoV2,"Randomized,Parallel Assignment,Treatment,Single (Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,480
NCT04436471,Completed,"June 17, 2020","August 10, 2020",Preventive Immunization COVID-19,"Non-Randomized,Parallel Assignment,An open, prospective, two-stage, non-randomized, first-phase study involving healthy volunteers,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:60 Years",No,38
NCT04435275,Not yet recruiting,"June 30, 2020","May 1, 2021",COVID-19,"Randomized,Crossover Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,50
NCT04407585,Recruiting,"June 1, 2020","May 10, 2021",Covid-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000000
NCT04353583,Recruiting,"April 21, 2020","March 31, 2021","Acute Kidney Injury,Corona Virus Infection","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04363502,Recruiting,"May 7, 2020",December 2020,Covid19,"Randomized,Parallel Assignment,This is a randomized, double-blind, placebo-controlled, design. We propose the administration of an investigational drug in patients with high predicted short-term mortality secondary to COVID-19 disease. 30 Patients will be randomly assigned in a 1:1 ratio to two study arms that will receive clazakizumab at a dose of 25 mg or placebo.,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:100 Years",No,30
NCT04527575,"Active, not recruiting","July 27, 2020","October 4, 2020",Covid19,"Randomized,Parallel Assignment,A simple, blind, placebo-controlled, randomized study involving healthy volunteers,Prevention,Single (Participant),Masking in Phase 2","gender:All,Min Age:18 Years,Max Age:60 Years",No,100
NCT04432805,Recruiting,"June 15, 2020","June 15, 2021",Pregnant Women Suspected of COVID-19,"N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:Female,Min Age:18 Years,Max Age:N/A",No,160
NCT04425733,Withdrawn,"July 7, 2020","November 10, 2020","Coronavirus Disease 2019 (COVID-19),Pneumonia,Hypoxemia","Randomized,Sequential Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:80 Years",No,0
NCT04357366,Recruiting,"April 15, 2020","April 15, 2022","COVID-19,Virus Diseases,Corona Virus Infection,Lower Respiratory Tract Infection Viral","N/A,Single Group Assignment,Treatment with anakinra and trimethoprim/sulfamethoxazole,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04403685,Terminated,"May 8, 2020","July 21, 2020","COVID,SARS Pneumonia,Cytokine Release Syndrome","Randomized,Parallel Assignment,Prospective, randomized, superiority, open-label, controlled trial. Randomization 1:1 to best supportive care (BSC) versus Tocilizumab + BSC,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,129
NCT04551547,Not yet recruiting,"September 28, 2020",September 2021,COVID-19,"Randomized,Parallel Assignment,Prevention,Double (Participant, Investigator)","gender:All,Min Age:3 Years,Max Age:17 Years",No,552
NCT04497402,Not yet recruiting,"September 1, 2020","June 1, 2022",Covid19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,88
NCT04331795,Completed,"April 4, 2020","June 5, 2020",COVID-19,"Non-Randomized,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,32
NCT04417257,Recruiting,"June 29, 2020","January 15, 2021",COVID-19 Disease,"Randomized,Parallel Assignment,Double-blind, randomized, parallel groups and placebo-controlled trial,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Patients will be randomly assigned to take either the active drug (LAU-7b capsule) or a matching inactive placebo (inactive capsule)","gender:All,Min Age:45 Years,Max Age:N/A",No,240
NCT04409535,"Active, not recruiting","May 7, 2020","March 31, 2021","Activities,Mental Health Issue,Life Style","Ecologic or Community,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:85 Years",No,500
NCT04352517,Recruiting,"March 16, 2020","September 30, 2020","Sedentary Behavior,Mental Health Wellness 1","Ecologic or Community,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,3500
NCT04489628,Not yet recruiting,"August 1, 2020","August 1, 2021",SARS-CoV Infection,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,110
NCT04360096,Not yet recruiting,"July 1, 2020","November 30, 2020","SARS-CoV 2,COVID,ARDS,ALI,Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS),Dyspnea","Randomized,Parallel Assignment,Multicenter Randomized Placebo-controlled Trial,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Only the study pharmacist will be aware of treatment assignment","gender:All,Min Age:12 Years,Max Age:85 Years",No,288
NCT04462757,"Active, not recruiting","May 28, 2020","September 30, 2020",COVID-19,"Randomized,Parallel Assignment,Patients will be randomly assigned to one of two arms:-
Subcutaneous arm: 100mg anakinra SC will be administered subcutaneously at consistent times that are convenient and practical for the patients and research/nursing staff providing there is a minimum 8 hours and maximum 16 hours between administrations.
Intravenous arm: 100mg anakinra in 100mL 0.9% NaCl will be administered intravenously four times a day every 6 hours.,Health Services Research,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,5
NCT04372979,Not yet recruiting,May 2020,May 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:80 Years",No,80
NCT04468581,"Active, not recruiting","March 8, 2020","July 31, 2020",Coronavirus,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:21 Years,Max Age:N/A",No,500
NCT04404270,Recruiting,"May 26, 2020",February 2021,Sars-CoV2,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2500
NCT04458948,"Active, not recruiting","March 24, 2020","March 24, 2025",COVID-19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,10000
NCT04349631,Enrolling by invitation,"April 22, 2020","December 31, 2020",COVID-19,"N/A,Single Group Assignment,Prevention,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",N/A,56
NCT04449081,Completed,"April 25, 2020","June 20, 2020","Acute Respiratory Distress Syndrome,Corona Virus Infection,Acute Lung Injury,Fever,Myalgia,Cough,Dyspnea,Septic Shock,Bleeding","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:30 Years",No,215
NCT04374461,Recruiting,"May 1, 2020",May 2021,Covid-19,"Non-Randomized,Parallel Assignment,This is a single-institution study that will be open at MSKCC's Manhattan campus. Patients will be enrolled into 2 separate arms. The mechanically ventilated &/or managed in a critical-care arm is closed to accrual as of September 2020.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,84
NCT04327401,Terminated,"April 13, 2020","July 22, 2020","Coronavirus Infection,Pneumonia, Viral,Acute Respiratory Distress Syndrome","Randomized,Parallel Assignment,Dexamethasone. After randomization, dexamethasone 20mg IV 1x/day for 5 days, followed by 10mg IV 1xd for 5 days + standard treatment (according to the treatment protocol for 2019-nCoV infection).
Standard treatment (according to the treatment protocol for 2019-nCoV infection).,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,299
NCT04408235,Not yet recruiting,June 2020,June 2021,"COVID,Pneumonia, Viral,Coagulation Disorder","Randomized,Parallel Assignment,This is a multicentre, randomised controlled, open label, investigator sponsored, two arms study.,Treatment,Single (Investigator),Randomisation will be centrally performed by using a secure, web-based system, which will be developed by the Methodological and Statistical Unit at the Azienda Ospedaliero-Universitaria of Modena. Randomisation stratified by 4 factors: 1) Gender (M/F); 2) Age (<75/≥75 years); 3) BMI (<30/≥30); 4) Co-morbidities (0-1/>2) with random variable block sizes will be generated by STATA software. The web-based system will guarantee the allocation concealment.","gender:All,Min Age:18 Years,Max Age:80 Years",No,300
NCT04429529,"Active, not recruiting","June 9, 2020",February 2021,Coronavirus Disease-2019 (COVID-19),"Randomized,Parallel Assignment,Participants are assigned to either treatment or placebo,Treatment,Double (Participant, Investigator)","gender:All,Min Age:21 Years,Max Age:50 Years",No,32
NCT04323644,Recruiting,"January 1, 2020","September 30, 2020","COVID-19,Coronavirus,Surgery","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1000
NCT04460703,Completed,"July 3, 2020","July 8, 2020","Vaccination,COVID-19","Randomized,Parallel Assignment,In this study, 2/15 of participants will be assigned to a control message (bird feeding passage), 3/15 of sample to a baseline vaccine message, and 1/15 to each of the 10 other treatment arms.,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,4000
NCT04546191,Completed,"July 1, 2020","September 1, 2020",Covid19,"Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1580
NCT04363333,"Active, not recruiting","April 27, 2020","December 31, 2020","COVID,Obstructive Sleep Apnea,Pneumonia","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,320
NCT04344665,"Active, not recruiting","April 23, 2020",January 2021,"Surgery,Perioperative Complication,COVID","Randomized,Parallel Assignment,Prevention,Single (Outcomes Assessor)","gender:All,Min Age:40 Years,Max Age:N/A",No,905
NCT04376814,Completed,"March 29, 2020","May 25, 2020","COVID-19,Favipiravir,Kaletra,Hydroxychloroquine,Lopinavir/Ritonavir","Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:16 Years,Max Age:100 Years",No,40
NCT04475302,Recruiting,"July 1, 2020",May 2021,COVID,"Non-Randomized,Single Group Assignment,In this study, as we are employing a control group that is not vaccinated against the disease to be prevented, but some clinical data are available to support the likely efficacy of the candidate vaccine, we will use unbalanced randomization and enrol participants to control group in the ratio of 2:1, so that majority of the study participant will receive the vaccine,Prevention,None (Open Label)","gender:All,Min Age:60 Years,Max Age:80 Years",No,2175
NCT04452773,Recruiting,"July 14, 2020",December 2021,COVID19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,315
NCT04403035,Recruiting,"May 10, 2020","May 9, 2021",Covid-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:95 Years",No,100
NCT04412460,Recruiting,"March 20, 2020","December 31, 2021","COVID,ARDS, Human","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04330638,Recruiting,"April 3, 2020",December 2020,COVID-19,"Randomized,Factorial Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,342
NCT04367545,Recruiting,"April 16, 2020",July 2020,"COVID,RT-ddPCR Multiplex","N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04276688,Completed,"February 10, 2020","March 31, 2020",Novel Coronavirus Infection,"Randomized,Parallel Assignment,open-label randomised controlled trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,127
NCT04573764,Not yet recruiting,"October 1, 2020","January 1, 2022",COVID-19,"Randomized,Crossover Assignment,Randomized placebo-controlled double-blinded crossed-over acute intervention study.,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,12
NCT04434144,Completed,"May 2, 2020","June 5, 2020","Ivermectin,Hydroxychloroquine,COVID19","Case-Only,Prospective","sampling_method:Probability Sample,gender:All,Min Age:16 Years,Max Age:80 Years",No,116
NCT04447469,Recruiting,"July 27, 2020",April 2021,COVID,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,573
NCT04302766,Available,N/A,N/A,N/A,N/A,"gender:All,Min Age:N/A,Max Age:N/A",N/A,N/A
NCT04390022,"Active, not recruiting","July 31, 2020","December 30, 2020","Covid-19,Coronavirus Infection,SARS-CoV-2 Infection","Randomized,Parallel Assignment,SAINT is a double-blind, randomized controlled trial with two parallel groups that evaluates the efficacy of ivermectin in reducing nasal viral carriage at seven days after treatment in SARS-CoV-2 infected patients who are at low risk of progression to severe disease.,Treatment,Double (Participant, Investigator),Double blind","gender:All,Min Age:18 Years,Max Age:59 Years",No,24
NCT04358380,Enrolling by invitation,"April 15, 2020","December 31, 2020",Liver Injury,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:17 Years,Max Age:N/A",No,320
NCT04559035,Enrolling by invitation,"September 24, 2020","December 31, 2020",Covid19,"Randomized,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:55 Years,Max Age:N/A",No,200
NCT04558476,Recruiting,"September 1, 2020","September 1, 2022","Covid19,Mechanical Ventilation Complication,Corona Virus Infection,Respiratory Failure,SARS (Severe Acute Respiratory Syndrome)","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04542993,Not yet recruiting,September 2020,June 2022,"Covid19,SARS-CoV Infection","Randomized,Single Group Assignment,Placebo controlled Resveratrol and Zinc combination therapy,Supportive Care,Single (Participant),single blinded","gender:All,Min Age:18 Years,Max Age:75 Years",No,60
NCT02788903,"Active, not recruiting",March 2016,February 2021,"Obesity,Diabetes,Covid19","Cohort,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2000000
NCT04453371,Not yet recruiting,"October 15, 2020","February 15, 2021",Acute Respiratory Distress Syndrome,"Randomized,Parallel Assignment,Treatment,Double (Participant, Care Provider)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04368013,Not yet recruiting,"April 28, 2020","April 14, 2026",COVID-19,"N/A,Single Group Assignment,Screening,None (Open Label)","gender:All,Min Age:15 Years,Max Age:100 Years",No,400
NCT04365231,Not yet recruiting,April 2020,January 2021,COVID19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:Female,Min Age:18 Years,Max Age:N/A",No,50
NCT04357496,Not yet recruiting,"April 20, 2020","October 30, 2020","Fever,Pneumonia,Cough","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:60 Years,Max Age:N/A",No,400
NCT04441710,Not yet recruiting,July 2020,January 2022,COVID,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,2500
NCT04330300,Suspended,"April 30, 2020","December 1, 2021","Hypertension,COVID-19","Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:60 Years,Max Age:N/A",No,2414
NCT04537208,Recruiting,"September 3, 2020",October 2021,COVID-19 (Healthy Volunteers),"Randomized,Parallel Assignment,This is a parallel group prevention study. Participants from 2 age groups (adults 18 through 49 years of age and adults 50 years of age and older) will receive either 1 injection (Cohort 1) or 2 injections (Cohort 2) of study vaccine or placebo control.
As a precautionary step, a sentinel safety cohort of 6 participants (younger adults only) within each dosing group from Cohort 1 will be enrolled. An early safety data review will be performed, including evaluation of safety data and laboratory measures to Day 9. Upon acceptable safety demonstrated from unblinded data review by limited members of the Sponsor Study Team, the remaining participants will be enrolled simultaneously.,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Participants, outcome assessors, Investigators, laboratory personnel, and the majority of Sponsor study staff will be blinded to vaccine group assignment; injection schedule will be unblinded and those preparing/administering the study interventions will be unblinded.","gender:All,Min Age:18 Years,Max Age:N/A",No,440
NCT04442165,Not yet recruiting,"July 15, 2020","July 14, 2021",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,15393
NCT04461379,Recruiting,"July 21, 2020","January 1, 2021","BCG,COVID-19,SARS-CoV2,Corona Virus Infection","Randomized,Parallel Assignment,A randomized double-blinded clinical trial, using computer software, participants will be allocated between two groups:
Intervention: BCG vaccine intradermally 0.1 ml, equivalent to 0.075 mg of attenuated Mycobacterium bovis. (Tokio 172 strain). The application technique is based on the National Vaccination Manual version 2017.
Comparator: Placebo, intradermally 0.1 ml of NaCl 0.9%,Prevention,Triple (Participant, Care Provider, Outcomes Assessor),Participants, researchers (including members of the research team that will assess outcomes), and treating physicians or health personnel (should the patient require in-hospital management) will be blinded to the treatment group to which the patients were randomized. Only the personnel who apply the vaccine will not be blinded to the treatment group to which the patients were randomized (this personnel will not have any further contact with the patients or provide any other type of patient care).","gender:All,Min Age:18 Years,Max Age:N/A",No,908
NCT04424355,Recruiting,"May 19, 2020","June 20, 2021","Coronavirus Infections,Pneumonia","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,115
NCT04348448,Not yet recruiting,April 2020,September 2020,COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,100
NCT04422626,Not yet recruiting,"July 1, 2020","December 1, 2022","SARS-CoV-2,COVID-19","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,42
NCT04472559,Not yet recruiting,"July 25, 2020","February 25, 2021","Quality of Life,Stress","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04544176,"Active, not recruiting","January 1, 2020","January 1, 2021",Covid19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:16 Years,Max Age:100 Years",No,34000
NCT04449978,Recruiting,"April 9, 2020","December 31, 2022","Coronavirus,COVID-19,Virus,Family and Household,Infection Viral","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:10 Years",No,1082
NCT04507867,Not yet recruiting,August 2020,December 2020,"Covid19,Diabetes Mellitus,Hypertension,Obesity","Randomized,Sequential Assignment,Supportive Care,Single (Investigator)","gender:All,Min Age:30 Years,Max Age:75 Years",No,240
NCT04342650,Completed,"April 8, 2020","June 8, 2020","COVID-19,SARS-CoV Infection,Severe Acute Respiratory Syndrome (SARS) Pneumonia,Clinical Trial","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,152
NCT04388436,"Active, not recruiting","May 11, 2020","October 10, 2021",COVID,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04381377,Recruiting,"April 29, 2020",April 2021,"Infections, Coronavirus","Randomized,Parallel Assignment,Treatment,Triple (Participant, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:85 Years",No,394
NCT04417374,Completed,"May 1, 2020","June 30, 2020","COVID 19,Disease Outbreak,Mental Disorders","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,94
NCT04369300,Recruiting,"April 24, 2020","February 24, 2021",COVID-19,"Other,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:90 Years",No,1000
NCT04399798,Not yet recruiting,"May 15, 2020","November 15, 2020",Corona Virus Infection,"N/A,Single Group Assignment,Proof-of-concept trial with an exploratory single-arm proof of concept Phase IIa study,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:74 Years",No,13
NCT04375202,Recruiting,"April 18, 2020","October 31, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,308
NCT04367740,Enrolling by invitation,"April 28, 2020",April 2021,"Asymptomatic Condition,Infection Viral,Coronavirus Infections,Severe Acute Respiratory Syndrome Coronavirus 2,Coronaviridae Infections,RNA Virus Infections,Virus Diseases,Communicable Disease","Case-Only,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:99 Years",No,10000
NCT04279899,Recruiting,"February 1, 2020","December 31, 2020","Neonatal Infection,Perinatal Problems,Infectious Disease","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:28 Days",No,100
NCT04371354,Recruiting,"April 27, 2020","July 27, 2020","Covid-19 Disease,Endoscopy Unit","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04368208,Recruiting,"April 29, 2020","December 14, 2020",Postnatal Depression,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:50 Years",No,900
NCT04425005,Recruiting,"May 10, 2020",February 2021,"Bariatric Surgery,Obesity","Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:80 Years",No,70
NCT04344119,Recruiting,"April 9, 2020","June 30, 2020","Skin Manifestations,COVID,Chilblains","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:90 Years",No,30
NCT04402905,Recruiting,"June 15, 2020","August 15, 2020",Coronavirus Infection,"Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,450
NCT04373161,Completed,"March 20, 2020","April 22, 2020","Sars-CoV2,COVID-19,COVID","N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,209
NCT04506515,Completed,"April 9, 2020","April 30, 2020","Covid19,Stress, Psychological,Work Related Stress,Epidemic Disease,SARS-CoV Infection","Ecologic or Community,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:70 Years",No,3000
NCT04394078,Completed,"May 6, 2020","May 18, 2020","Depression,Quality of Life,Covid 19,Social Isolation","Ecologic or Community,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:15 Years,Max Age:65 Years",No,543
NCT04386551,Recruiting,"May 11, 2020",December 2020,"Sars-CoV2,RT-PCR,Saliva Collection,Nasopharyngeal Sample","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,225
NCT04395781,Recruiting,"May 18, 2020","December 31, 2023","COVID,Pediatric Disorder","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:21 Years",No,2000
NCT04423861,Not yet recruiting,July 2020,August 2020,covid19,"Randomized,Parallel Assignment,Patients will be randomized to receive either nitazoxanide or placebo (1:1),Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04463472,"Active, not recruiting","June 29, 2020","July 31, 2021",COVID-19,"Non-Randomized,Sequential Assignment,Prevention,None (Open Label)","gender:All,Min Age:20 Years,Max Age:65 Years",No,30
NCT04368897,Recruiting,"May 1, 2020","December 1, 2020","SARS-CoV 2,COVID,COVID-19,Androgenetic Alopecia,Androgen Receptor Abnormal,Androgen Deficiency","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:Male,Min Age:18 Years,Max Age:N/A",No,200
NCT04531618,Recruiting,"August 13, 2020",December 2021,"Child Development,Mother-Infant Interaction,COVID-19","Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:N/A,Max Age:72 Hours",No,280
NCT04363632,Completed,"April 2, 2020","June 30, 2020","Sars-CoV2,Cancer","Cohort,Other","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1231
NCT04355676,Not yet recruiting,"April 30, 2020","August 30, 2020",Coronavirus Infection,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04437706,Not yet recruiting,"October 1, 2020","June 30, 2021","COVID-19,SARS-CoV 2","Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04302519,Not yet recruiting,"March 5, 2020","July 30, 2021",COVID-19,"N/A,Single Group Assignment,Dental pulp mesenchymal stem cells were injected intravenously,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,24
NCT04397471,Not yet recruiting,May 2020,December 2021,Healthy Volunteers for Bone Marrow Donation,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:40 Years",No,10
NCT04361552,Withdrawn,"April 7, 2020","June 2, 2020","Cerebrovascular Accident,Chronic Obstructive Pulmonary Disease,Chronic Renal Failure,Coronary Artery Disease,Diabetes Mellitus,Malignant Neoplasm,SARS Coronavirus 2 Infection","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04465513,Not yet recruiting,"August 31, 2020","August 31, 2021","Asthma; Eosinophilic,COVID,Covid-19","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,100
NCT04462393,Completed,"March 6, 2020","May 6, 2020","COVID-19,Critical Illness","Cohort,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1563
NCT04255017,Recruiting,"February 1, 2020","July 1, 2020",2019-nCoV,"Randomized,Parallel Assignment,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04575064,"Active, not recruiting","June 29, 2020",November 2022,"SARS-CoV-2 Infection,COVID-19,Moderate and Severe COVID-19","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04470531,Recruiting,"July 12, 2020","January 30, 2021","Covid19,Severe COVID-19 Patients","Randomized,Parallel Assignment,Arm A :control group will receive standard treatment, Arm B: experimental group will receive standard care and oral co-triamoxazole,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,94
NCT04392453,Not yet recruiting,May 2020,December 2020,Stroke,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:85 Years",No,40
NCT04374513,Recruiting,"May 2, 2020",April 2021,Covid19,"Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,50
NCT04399681,Recruiting,"May 10, 2020","September 10, 2020","COVID,Pneumonia, Viral","N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04540393,Not yet recruiting,"August 26, 2020","March 5, 2021",COVID-19,"N/A,Single Group Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04384965,Recruiting,"May 12, 2020","November 1, 2022",Major Depressive Disorder,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04379986,Not yet recruiting,"May 1, 2020","June 1, 2020",Blood Pressure,"Non-Randomized,Single Group Assignment,Device Feasibility,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04425460,Not yet recruiting,June 2020,September 2020,COVID-19,"Randomized,Parallel Assignment,This is a multi-center, randomized, double-blind, placebo-controlled (1:1) clinical study to explore the efficacy and safety of Favipiravir,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:75 Years",No,256
NCT04385121,Recruiting,"April 16, 2020",March 2021,"Covid-19,Stress Disorders, Post-Traumatic,Anxiety,Depression","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04568551,Recruiting,"October 1, 2020","July 31, 2021",Anxiety State,"Cohort,Prospective","sampling_method:Probability Sample,gender:Female,Min Age:18 Years,Max Age:N/A",No,300
NCT04570189,Not yet recruiting,September 2020,January 2021,COVID-19,"Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,40
NCT04502342,Enrolling by invitation,"June 1, 2020","September 30, 2020",Covid19,"Randomized,Parallel Assignment,Eligible consenting symptomatic patients with COVID-19 confirmed by a positive Polymerase Chain Reaction test were subjected to the 10 days of treatment allocated to each of the 3 arms of the trial. Virological clearance is assessed on days 3, 6 and 14. Side effects and the onset of COVID symptoms are evaluated throughout the trial period. Clinical, paraclinical and laboratory examinations are occasionally provided. The data are statiscally processed.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04416100,Recruiting,"April 29, 2020","April 28, 2022","Covid-19,Pulmonary Fibrosis","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,130
NCT04558437,Recruiting,"June 12, 2020","December 31, 2020","Post Traumatic Stress Disorder (PTSD),Anxiety,Depression,Epidemic Disease,COVID19","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,20000
NCT04547218,Recruiting,"June 22, 2020","December 31, 2020","Age Problem,Surgery,Depression, Anxiety","Case-Only,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:65 Years,Max Age:N/A",No,150
NCT04380935,Recruiting,"May 18, 2020","October 31, 2020","COVID,Acute Respiratory Distress Syndrome","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04561219,"Active, not recruiting","April 19, 2020","October 2, 2020","Covid19,Corona Virus Infection,Pneumonia, Viral","Randomized,Parallel Assignment,Hospitalized patients with clinical signs of COVID-19, and either chest tomography scans suggestive of COVID-19 or confirmed by RT-PCR molecular tests, will be randomly divided into 2 groups: experimental and control groups.
Experimental group: 250 hospitalized patients diagnosed with COVID-19 derived pneumonia will receive nitazoxanide 500mg 8/8 hs for 5 days. Control group: 250 hospitalized patients diagnosed with COVID-19 derived pneumonia will receive placebo 8/8 hs for 5 days.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Patients were randomly allocated into one of the two groups: A or B. Patients received labelled medication: A or B, by the pharmacist. Patients received an identification number, so care providers, outcomes assessors and investigators did not know anything regarding the patients' groups.","gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT02735707,Recruiting,"April 11, 2016",December 2023,"Community-acquired Pneumonia, Influenza, COVID-19","Randomized,Factorial Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,7100
NCT04536363,Not yet recruiting,"October 1, 2020","March 1, 2021",Covid19,"Randomized,Parallel Assignment,Study type: Open randomized clinical trial. Study phase: Phase II Design: Experimental in parallel Two management groups Intermediate analysis will be carried out when completing 20%, 40%, 60% and 80% of the planned sample. All adjusted statistical analysis will be carried out conditionally, predicting the effect of the stratification of the randomization process.
The statistical analysis will be carried out in accordance with the principle of ""intention to treat"",Treatment,None (Open Label),There are no masking techniques in assigning treatment to patients, as this is an open study. Nor is any procedure for urgently opening emergency codes applicable. The statistical analysis will be carried out without the epidemiologist in charge knowing or being able to identify the group of origin of the patients (control / intervention). To guarantee this, the data of the patients will be reported to the epidemiologist without any identification data and through a code whose sole knowledge at the time of delivery will be the responsibility of the principal investigator. Interim comparisons and analysis will be carried out for mortality and adverse events in the following follow-up stages according to the number of patients achieved: 20%, 40%, 60%, 80% and final.","gender:All,Min Age:18 Years,Max Age:N/A",No,284
NCT04438941,Recruiting,"March 25, 2020","June 20, 2020",Sars-CoV2,"Case-Only,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04374656,Recruiting,"May 18, 2020",May 2021,"Conjunctivitis,SARS-CoV-2,COVID-19,Ocular Infection, Viral,Ocular Inflammation","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04383470,Recruiting,"April 26, 2020",June 2022,"Mental Health Wellness 1,Pandemic","Ecologic or Community,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:6 Years,Max Age:N/A",No,100000
NCT04384588,Recruiting,"April 7, 2020","April 6, 2021","COVID-19 Infection,Cancer Patients,General Population","Non-Randomized,Parallel Assignment,Multicenter, non-randomized, 4 arms,Treatment,None (Open Label)","gender:All,Min Age:15 Years,Max Age:N/A",No,100
NCT04503434,Completed,"May 15, 2020","June 6, 2020","Patient Preference,COVID-19","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,517
NCT04542434,Not yet recruiting,"November 1, 2020","May 1, 2021",Covid19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,148
NCT04371432,Recruiting,"October 12, 2020","June 1, 2025","COVID-19,Coronavirus 2019","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:3 Years,Max Age:N/A",No,2500
NCT04462367,Not yet recruiting,"July 1, 2020","December 20, 2022","COVID19,Coronavirus Infection,Pregnancy Disease,Severe Acute Respiratory Syndrome","Cohort,Other","sampling_method:Non-Probability Sample,gender:Female,Min Age:N/A,Max Age:N/A",No,180
NCT04345887,Not yet recruiting,"April 21, 2020","October 21, 2020","Respiratory Distress Syndrome, Adult","Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04341714,Recruiting,"March 16, 2020","June 15, 2020","Efficacy, Self,Satisfaction, Patient,Telemedicine","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,450
NCT04378257,Not yet recruiting,"June 1, 2020","October 20, 2020","Depressive Symptoms,Generalized Anxiety","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:65 Years",No,70
NCT04393558,Recruiting,"April 20, 2020","December 31, 2022","COVID-19,Healthy Control","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:95 Years",No,100
NCT03331445,Recruiting,"October 24, 2017","March 31, 2021","Respiratory Tract Infections,Corona Virus Infection","Sequential Assignment,Open label safety study (COVID-19 Sub-study),Treatment,None (Open Label)","gender:All,Min Age:19 Years,Max Age:N/A",No,20
NCT04348227,"Active, not recruiting","January 1, 2019","February 4, 2021",Ventilator Associated Pneumonia,"Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,120
NCT04445233,Recruiting,"April 29, 2020",December 2020,COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:1 Year,Max Age:N/A",No,400
NCT04516746,Not yet recruiting,"August 17, 2020","October 5, 2022","COVID-19,SARS-CoV-2","Randomized,Parallel Assignment,Participants are assigned to one of two or more groups in parallel for the duration of the study.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double Blind: two or more parties are unaware of the intervention assignment.","gender:All,Min Age:18 Years,Max Age:N/A",No,30000
NCT04411667,Recruiting,"April 28, 2020","November 30, 2020",Sars-CoV2,"Randomized,Parallel Assignment,Subjects will be randomized into one of two groups: Standard of Care plus IVIG or Standard of Care.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04575532,Enrolling by invitation,"October 5, 2020","January 22, 2021",Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04477473,Recruiting,"June 30, 2020","August 31, 2020","COVID-19 Pandemic,Vulnerable Subjects,Long-term Non-invasive Ventilation","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,100
NCT04379531,Completed,"April 25, 2020","May 22, 2020","Pneumonia,Coronavirus Infection","Non-Randomized,Crossover Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,230
NCT04568356,Completed,"April 24, 2020","September 24, 2020",SARS CoV-2,"N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04501172,Completed,"June 25, 2020","August 14, 2020",Covid19,"Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:85 Years",No,1214
NCT04355728,"Active, not recruiting","April 25, 2020","December 31, 2020","Corona Virus Infection,ARDS,ARDS, Human,Acute Respiratory Distress Syndrome,COVID-19","Randomized,Parallel Assignment,The trial has two groups, each with 12 subjects (n=24). All eligible subjects will be randomized to either the treatment group or standard of care, and randomization will be stratified by ARDS severity.,Treatment,Triple (Participant, Care Provider, Investigator),Double-Blinding Trial","gender:All,Min Age:18 Years,Max Age:N/A",No,24
NCT04526405,Recruiting,"July 14, 2020","October 30, 2020","Thalassemia Major,Covid19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,81
NCT04359329,Recruiting,"April 20, 2020","November 15, 2020",COVID,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,110
NCT04490486,Not yet recruiting,"March 1, 2021","June 1, 2024","COVID-19,Acute Respiratory Distress Syndrome,Corona Virus Infection","Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,21
NCT04373824,Recruiting,"April 25, 2020","July 25, 2020",COVID,"Non-Randomized,Crossover Assignment,25 subjects in each Arm,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,50
NCT04444986,Completed,"June 5, 2020","June 13, 2020",Bioequivalence,"Randomized,Crossover Assignment,Other,None (Open Label)","gender:Male,Min Age:18 Years,Max Age:40 Years",No,30
NCT04456049,Not yet recruiting,July 2020,December 2021,COVID-19 Infection,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:Male,Min Age:50 Years,Max Age:N/A",No,90
NCT04524507,Recruiting,"August 27, 2020",May 2021,COVID-19,"Randomized,Parallel Assignment,This study has 2 treatment arms and participants will be assigned/randomized to one arm:
CCP1 - CCP tested for the presence of anti-SARS-CoV-2 antibodies and assigned high-titer
CCP2 - CCP tested for the presence of anti-SARS-CoV-2 antibodies and assigned standard-titer,Treatment,Double (Participant, Investigator),This study is double-blinded so neither the participant nor the study team/investigators will know which plasma treatment (CCP1 or CCP2) that the participant is receiving.","gender:All,Min Age:18 Years,Max Age:99 Years",No,56
NCT04418505,Recruiting,"September 2, 2020","March 1, 2021",COVID-19,"Randomized,Parallel Assignment,Prospective, randomized trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:65 Years",No,280
NCT04350684,Enrolling by invitation,"April 15, 2020","April 24, 2020",COVID-19,"Randomized,Parallel Assignment,The present study is a randomized, double-blind, placebo-controlled, clinical trial, with the approval of the ethics committee will be conducted on patients who have a positive test confirming COVID-19 in Loghman Hakim Medical Education Center in Tehran. Patients will be randomly assigned to the two arms of the study and after completing the course of treatment and collecting and analyzing the necessary information from each patient, the results of the study will be published both on this site and in the form of an article in a reputable international journal.,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04525287,Recruiting,"February 20, 2020","August 20, 2020","Coronavirus Infection,COVID19","Case-Crossover,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1000
NCT04453384,Recruiting,"September 1, 2020",December 2021,SARS Virus,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:85 Years",No,368
NCT04321421,Completed,"March 17, 2020","May 7, 2020",COVID-19,"N/A,Single Group Assignment,Longitudinal assessment of COVID-19 patients treated with hyperimmune plasma,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,49
NCT04357782,"Active, not recruiting","April 16, 2020","October 15, 2020","COVID-19,Hypoxia","Non-Randomized,Single Group Assignment,Parallel: Participants are assigned to one of two or more groups in parallel for the duration of the study,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:99 Years",No,20
NCT04359914,Recruiting,"April 15, 2020","April 1, 2021","Critical Illness,COVID-19,Central Nervous System Injury,Delirium,Encephalopathy","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,80
NCT04378686,Recruiting,"April 23, 2020","May 1, 2022","SARS-CoV 2,End Stage Renal Failure on Dialysis","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04510519,Not yet recruiting,"September 1, 2020","June 30, 2021","Major Depressive Disorder,Generalized Anxiety","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,50
NCT04364828,Not yet recruiting,April 2020,August 2021,COVID-19,"Non-Randomized,Sequential Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04343898,"Active, not recruiting","April 1, 2020","August 1, 2022",Coronavirus Infection,"Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,5253
NCT04367792,"Active, not recruiting","April 23, 2020",March 2021,COVID-19,"Case-Control,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04362332,Terminated,"April 14, 2020","June 8, 2020",COVID-19,"Randomized,Parallel Assignment,Supportive care + chloroquine base arm: loading dose 600mg, followed by 300mg 12 hours later, followed by 300mg bid for 4 days; total treatment duration of 5 days
Supportive care + hydroxychloroquine arm: loading dose 400mg bid, followed by 200mg bid for 4 days; total treatment duration of 5 days.
Supportive care only.,Treatment,None (Open Label),cluster randomized design","gender:All,Min Age:18 Years,Max Age:110 Years",No,25
NCT04451174,Recruiting,"June 23, 2020","September 30, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:90 Years",No,184
NCT04394390,Enrolling by invitation,"May 1, 2020","June 30, 2020",COVID,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04303507,Recruiting,"April 29, 2020",April 2021,"COVID19,Coronavirus,Acute Respiratory Illnesses","Randomized,Parallel Assignment,Prevention,Double (Participant, Investigator)","gender:All,Min Age:16 Years,Max Age:N/A",No,40000
NCT04435119,Completed,"March 15, 2020","May 15, 2020",Coronavirus,"Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:70 Years,Max Age:N/A",No,96
NCT04366934,Recruiting,"May 4, 2020","September 15, 2022","Coronavirus Infection,Severe Acute Respiratory Syndrome,Sars-CoV2","Case-Control,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,24
NCT04354870,Completed,"April 3, 2020","October 1, 2020",COVID-19,"Non-Randomized,Parallel Assignment,Total number of participant: 350 (Group A and B)
Group A: projected 300 (HCW choose to be provided HCQ)
Group B: projected 50 (HCW choose not to be provided HCQ),Treatment,None (Open Label),Open Label","gender:All,Min Age:18 Years,Max Age:N/A",No,130
NCT04339712,Recruiting,"April 2, 2020","April 1, 2022","COVID-19,Virus Diseases,Macrophage Activation Syndrome,Corona Virus Infection","Non-Randomized,Factorial Assignment,Treatment with tocilizumab or anakinra,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04367142,Not yet recruiting,September 2020,December 2020,Sars-CoV2,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,200
NCT04442230,Recruiting,"September 29, 2020",February 2021,Coronavirus Infection,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator),Double-Blind","gender:All,Min Age:18 Years,Max Age:N/A",No,96
NCT04413877,Not yet recruiting,October 2020,November 2021,"Frailty Syndrome,COVID-19,Healthy Aging,Old Age; Debility","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:65 Years,Max Age:N/A",No,600
NCT04559113,Recruiting,"May 1, 2020","October 30, 2020","SARS-CoV Infection,SARS (Severe Acute Respiratory Syndrome)","N/A,Single Group Assignment,quasi-experimental,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,200
NCT04379284,Recruiting,"May 8, 2020","July 31, 2021",COVID19,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:45 Years",No,100
NCT04384549,Recruiting,"May 20, 2020","February 20, 2021","Infection,Viral, Agent as Cause of Disease Classified Elsewhere","Randomized,Parallel Assignment,Prevention,Single (Participant)","gender:All,Min Age:18 Years,Max Age:N/A",No,1120
NCT04546737,Recruiting,"September 8, 2020",May 2022,"Covid19,Neurological Manifestations,Brain Damage","Non-Randomized,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04335123,Recruiting,"March 25, 2020",October 2020,COVID-19,"N/A,Single Group Assignment,50 patients with COVID-19 and respiratory failure who meet criteria and agree to participation in the study will be placed on losartan 25 mg once daily on study day 0. If parameters are met the dose of losartan will be increased to 50 mg once daily on study day 3. Patients and/or surrogate decision maker who do not give consent to treatment will be asked to allow collection of data from their medical record for use as a control group.We will also collect medical information relating to safety criteria on historical controls treated at the University of Kansas Hospital in the 30 days prior to the study start date (3/25/2020) and during the study period.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04370821,Recruiting,"May 9, 2020","April 27, 2040","Occupational Exposure to SARS-CoV-2,COVID-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,20000
NCT04474249,Recruiting,"June 25, 2020",December 2022,"COVID19,ARDS,AKI,Circulatory Failure,Coagulation Disorder,Inflammatory Response","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04342689,Recruiting,"June 3, 2020","June 1, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:19 Years,Max Age:N/A",No,1500
NCT04368312,Not yet recruiting,"May 6, 2020","May 30, 2020","Psychological Distress,Quality of Life","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04409951,Not yet recruiting,November 2020,September 2021,"Event, Life Change","Case-Crossover,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:16 Years,Max Age:40 Years",No,100
NCT04492891,Not yet recruiting,"August 20, 2020","August 20, 2025",SARS (Disease),"Randomized,Parallel Assignment,Phase IIa clinical trial in which 75 non-ICU hospital inpatients will be randomized 2:1 to 7 days of Neoral (2.5mg/kg PO BID) + standard of care (SOC) or no CSA + SOC.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:90 Years",No,75
NCT04452565,Recruiting,"October 15, 2020","February 15, 2021","Coronavirus Infection,Severe Acute Respiratory Infection,Severe Acute Respiratory Syndrome Coronavirus 2","Randomized,Parallel Assignment,Prevention,Triple (Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:80 Years",No,525
NCT04483830,Completed,"June 5, 2020","September 7, 2020",Covid19,"Randomized,Parallel Assignment,prospective, single centre, randomized, placebo-control trial,Treatment,Single (Participant),placebo control","gender:All,Min Age:40 Years,Max Age:80 Years",No,243
NCT04254874,Recruiting,"February 1, 2020","July 1, 2020",2019-nCoV,"Randomized,Parallel Assignment,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04403477,Recruiting,"May 20, 2020","October 30, 2020","Covid19,Convalescence","Randomized,Parallel Assignment,Arm-A: Standard supportive treatment; Arm-B: Standard supportive treatment + CP 200 ml; Arm C: Standard supportive treatment + CP 400 ml,Treatment,None (Open Label)","gender:All,Min Age:16 Years,Max Age:N/A",No,20
NCT04409574,Not yet recruiting,June 2020,June 2021,"Infection, Coronavirus","Case-Only,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:50 Years",No,31
NCT04383483,Recruiting,"June 15, 2020","August 31, 2020",Coronavirus as the Cause of Diseases Classified Elsewhere,"Case-Only,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,100
NCT04460664,Enrolling by invitation,"August 14, 2020","February 15, 2021","COVID,Disseminated Intravascular Coagulation,Coagulation Disorder","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04427878,Not yet recruiting,"July 1, 2020","July 9, 2021",Covid-19 Patients,"N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,5
NCT04361565,Enrolling by invitation,"March 20, 2020","May 31, 2020",COVID-19 by SARS-CoV-2 Infection,"Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,50
NCT04457817,Not yet recruiting,September 2020,September 2021,COVID,"Randomized,Parallel Assignment,COVID-19 patients who require 2 liters of oxygen by nasal cannula (to maintain SpO2 >90%), will be eligible. Study participants will be randomized into standard of care and study patient cohorts. Both cohorts will receive standard monitoring and therapy. Patients in the study cohort will also be monitored with a CipherOx CR T1 tablet in a continuous manner to determine if maintaining CRI vales between 0.9-0.7 will: 1) help guide IV fluid (e.g. crystalloid, colloids, blood products) and medication therapy (e.g. diuretics); 2) allows earlier identification of patients who are poorly compensating and will require ICU level care; 3) reduces acute kidney injury (AKI) and/or need for continuous renal replacement therapy (CRRT); and 4) improves clinical outcomes.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,100
NCT04511962,Not yet recruiting,"August 12, 2020","January 20, 2022",Pulmonary Disease,"Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04463264,Recruiting,"June 26, 2020","October 26, 2020",COVID-19,"Randomized,Parallel Assignment,Randomized. Nitazoxanide : Placebo (2:1), parallel-group study,Treatment,Single (Participant),Simple blind design","gender:All,Min Age:18 Years,Max Age:59 Years",No,135
NCT04444700,Recruiting,"July 4, 2020","December 31, 2020","COVID,Coronavirus Infection,Severe Acute Respiratory Syndrome,Thromboembolism, Venous,Anticoagulants and Bleeding Disorders","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,462
NCT04443699,Not yet recruiting,"June 22, 2020","July 13, 2020",Mental Well-being,"Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,4000
NCT04430374,Recruiting,"June 2, 2020","December 31, 2020",Cardiovascular Diseases,"Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04498325,Not yet recruiting,"October 31, 2020","July 31, 2021","COVID-19,SARS-CoV-2","Randomized,Parallel Assignment,The study will open as a phase I study to test three different dose levels of NT-I7. Once a safe tolerated dose is established, the pilot portion of the study will be activated wherein participants will be randomized on a 1:1 basis to receive a single injection of NT-I7 (at the safe tolerated dose) or placebo.,Treatment,Triple (Participant, Care Provider, Investigator),The clinicians, participants, and clinical research coordinators will be blinded","gender:All,Min Age:18 Years,Max Age:N/A",No,42
NCT04385212,Completed,"March 13, 2020","April 14, 2020","Coronavirus Infection,Sars-CoV2,Elderly Infection,Old Age; Debility","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:65 Years,Max Age:N/A",No,230
NCT04382846,Not yet recruiting,"May 8, 2020","December 1, 2030","COVID,Corona Virus Infection","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04405999,Completed,"May 14, 2020","August 31, 2020",Increased Risk of SARS-CoV-2 Infection,"Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04405869,Recruiting,"April 29, 2020",April 2021,Pulmonary Thromboembolism,"Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04549350,Completed,"May 19, 2020","September 5, 2020",Sleep Quality,"Other,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:25 Years,Max Age:60 Years",No,217
NCT04401579,"Active, not recruiting","May 8, 2020","August 1, 2023",COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:99 Years",No,1034
NCT04492514,Recruiting,"May 20, 2020","May 31, 2021","COVID 19,SARS-CoV 2,Pneumonia","Randomized,Factorial Assignment,Factorial Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Quadruple (Particiapnt, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04268537,Not yet recruiting,"February 10, 2020","October 31, 2020","2019 nCoV, PD-1","Randomized,Parallel Assignment,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04379544,Recruiting,"April 23, 2020",December 2020,"Coronavirus,Respiratory Failure","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,105
NCT04551378,Recruiting,"July 13, 2020","December 31, 2021","COVID-19 Infection,Hematopoietic and Lymphoid Cell Neoplasm,Malignant Solid Neoplasm","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:39 Years",No,600
NCT04376684,Recruiting,"May 28, 2020","December 21, 2020",Severe Acute Respiratory Syndrome,"Randomized,Parallel Assignment,Participants will be randomized to receive either a blinded IV infusion of otilimab or placebo, in addition to standard of care.,Treatment,Double (Participant, Investigator),This is a double-blind study.","gender:All,Min Age:18 Years,Max Age:79 Years",No,800
NCT04373382,Recruiting,"July 27, 2020",February 2022,Burnout,"Randomized,Crossover Assignment,Hospital staff will receive support from Peer Resilience Champions, whose activities will, in part, be modelled on the role that psychiatrists acting as support coaches have played in during the acute phase of the pandemic. These include support, identification of needs, education, advocacy and resource navigation. In doing so, they follow evidence-based principles and guidelines.
A randomized cluster stepped wedge design will be used, with five clusters of clinical units and departments constructed in order to approximate the following goals: similar number of staff, comparable COVID-19 exposure, similar mix of staff by discipline and gender, number of clusters small enough to allow for the PRC intervention to be provided with at least six months of implementation within the two-year study after cross-over occurs. (Two arms).
The Enriched survey intervention will be a randomized controlled trial design with equal allocation (1:1) to both the express and enriched surveys. (Two arms).,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04401046,Recruiting,"May 20, 2020","October 30, 2020",Cancer,"N/A,Single Group Assignment,Health Services Research,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,4000
NCT04479280,Completed,"July 20, 2020","August 16, 2020",Coagulation Disorder,"Case-Control,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,70
NCT04471649,Recruiting,"June 15, 2020",November 2020,COVID,"Case-Control,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04407195,"Active, not recruiting","June 1, 2020","June 1, 2021","COVID-19,Mental Health Disorder","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04337359,Available,N/A,N/A,N/A,N/A,"gender:All,Min Age:6 Years,Max Age:90 Years",No,N/A
NCT04537585,Not yet recruiting,November 2020,December 2022,Covid19,"Randomized,Parallel Assignment,Investigators couldn't agree more to wait without to know how to treat their patients better and want to learn about therapeutic nutrition approach called TOMEKA versus prophylaxis dosing of antioxidant as Vernonia amygdalina as a study. Investigators are learning about that here in September, why wasn't that done in April? Investigators would submit to follow a parallel group, just speaking as researchers about randomisation, one of the reasons difficult to reach that elaborate study design is sometimes bureaucracy is just daunting.,Prevention,None (Open Label),The fact that you can't really study anything unless there's funding for it because the insurance companies and the hospitals are not going to pay for things on a trial unless there is funding. Then you add to that there is no funding for food as medicine, and things as herbs like Vernonia amygdalina that improve the quality of life in COVID-19 patients and they are not pharmaceutical. Those are sort of the real-world complaints, investigators would say, on the front lines to follow participants in parallel group i.e. compare the ones who take herbs as medicine for their survival and other who use others means to fight COVID-19 symptoms.","gender:All,Min Age:15 Years,Max Age:65 Years",No,2000
NCT04488549,Completed,"May 20, 2020","June 10, 2020","Colo-rectal Cancer,Colon Cancer,Rectal Cancer,Oncology,Surgery","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1051
NCT04351542,Completed,"March 6, 2020","April 12, 2020",Flu Like Illness,"Non-Randomized,Parallel Assignment,Supportive Care,Single (Care Provider),Ayurveda care provide was blinded","gender:All,Min Age:18 Years,Max Age:60 Years",No,32
NCT04516850,Not yet recruiting,"September 1, 2020","August 31, 2021",Covid19,"Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04409873,Not yet recruiting,"October 1, 2020","August 31, 2021","COVID-19,SARS-CoV 2,Severe Acute Respiratory Syndrome Coronavirus 2,Virus Disease,Coronavirus Infections,Pharyngeal Diseases","Randomized,Parallel Assignment,A blinded randomized controlled parallel group design trial,Supportive Care,Double (Participant, Outcomes Assessor),Study participants will be blinded to the solutions to the extent possible (i.e., similar packages with identification number bar codes).
The lab technician who evaluates the SARS-CoV-2 load in samples will be blinded to the solutions and study groups.","gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04433039,Completed,"May 22, 2020","June 14, 2020",COVID,"Case-Crossover,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:4 Years,Max Age:80 Years",No,130
NCT04441424,Completed,"April 3, 2020","June 1, 2020",IMMUNOTHERAPY,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,49
NCT04548934,Not yet recruiting,"September 13, 2020","December 31, 2020","Cardiopulmonary Resuscitation,Personal Protective Equipment","Randomized,Crossover Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:60 Years",No,28
NCT04439825,Not yet recruiting,"July 15, 2020","October 15, 2020",Mood,"Randomized,Crossover Assignment,Treatment,Single (Participant)","gender:All,Min Age:10 Years,Max Age:75 Years",No,45
NCT04334954,Recruiting,"August 26, 2020","March 31, 2022",SARS-COV2 Virus,"Case-Only,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,15000
NCT04448054,Recruiting,"May 20, 2020","November 20, 2021","Estimate, With the Contribution of Optimized MRI, the Prevalence of Neurological and Neurovascular Manifestations on Imaging in the Event of SARS-CoV-2","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04025580,Recruiting,"October 2, 2019","December 31, 2025","Healthy Volunteer,COVID-19","N/A,Single Group Assignment,Basic Science,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04335630,Recruiting,"March 30, 2020",March 2022,"Cardiovascular Diseases,COVID","Case-Control,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04372004,Recruiting,"May 8, 2020",June 2021,COVID-19,"Non-Randomized,Parallel Assignment,Each subject will be tested using 3 different samples on two testing platforms (serology and viral-RNA detection),Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:85 Years",No,100
NCT04362319,Completed,"May 15, 2020","May 31, 2020","Burnout, Professional,Depression,Medical Errors,Covid-19","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,85
NCT04434014,Recruiting,"June 8, 2020","June 28, 2020","Diet, Healthy","Ecologic or Community,Prospective","sampling_method:Probability Sample,gender:All,Min Age:20 Years,Max Age:60 Years",No,300
NCT04527614,Not yet recruiting,"September 1, 2020","May 30, 2021","Influenza, Human,SARS Virus,COVID-19,Espiratory Tract Infections","Parallel Assignment,Diagnostic,Double (Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04299152,Not yet recruiting,"May 10, 2020","November 10, 2020",Severe Acute Respiratory Syndrome (SARS) Pneumonia,"Randomized,Parallel Assignment,This is a prospective, two-arm, partially masked, single center clinical study to assess the safety, feasibility, and efficacy of SCE therapy for the treatment of patients with SARS-CoV-2.,Treatment,Single (Care Provider)","gender:All,Min Age:18 Years,Max Age:60 Years",No,20
NCT04465552,Recruiting,"July 10, 2020",December 2020,Coronavirus Infections,"Case-Control,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,750
NCT04459533,Completed,"June 1, 2020","June 1, 2020","Neuromuscular Blockade,Human Characteristics,Complication of Medical Care,Intensive Care Unit Acquired Weakness","Case-Control,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,250
NCT04327206,Recruiting,"March 30, 2020","March 30, 2022","Coronavirus Disease 2019 (COVID-19),Respiratory Illness,Corona Virus Infection,COVID-19","Randomized,Parallel Assignment,Phase III, two group, multicentre, randomised controlled trial,Prevention,Double (Participant, Outcomes Assessor),The control group will receive a placebo of 0.9% sodium chloride (NaCl). Members of the research team doing the follow-up of participants and analysis will be blinded to the group allocation (by the removal of this variable and all other variables related to BCG from the dataset) until the formal detailed statistical analysis plan is confirmed and signed by all investigators and all data cleaning/preparation is complete.","gender:All,Min Age:18 Years,Max Age:N/A",No,10078
NCT04434118,Enrolling by invitation,"March 20, 2020","December 30, 2020","Rheumatoid Arthritis,COVID","Case-Control,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:60 Years",No,600
NCT04354155,Recruiting,"June 2, 2020","October 15, 2022","Infection Viral,Thromboses, Venous,COVID-19","N/A,Single Group Assignment,Prevention,None (Open Label)","gender:All,Min Age:N/A,Max Age:18 Years",No,38
NCT04412265,Recruiting,"March 1, 2020","March 1, 2021",Covid19,"Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04349098,Recruiting,"April 17, 2020","August 31, 2020",Coronavirus Infection,"Randomized,Parallel Assignment,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:N/A",No,230
NCT04319315,Recruiting,"March 11, 2020","April 16, 2020",COVID-19,"Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:25 Years,Max Age:65 Years",No,400
NCT04344249,Recruiting,"April 10, 2020","September 1, 2021","IBD,COVID","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,850
NCT04528888,Not yet recruiting,"September 1, 2020","July 30, 2021","Covid19,SARS-CoV Infection,Pneumonia, Viral,Coagulopathy","Randomized,Parallel Assignment,The study is designed as a multicenter, national, interventional, randomized, investigator sponsored, three arms study. Patients, who satisfy all inclusion criteria and no exclusion criteria, will be randomly assigned to one of the three treatment groups in a ratio 1:1:1. A block randomisation will be used with variable block sizes (block size 4-6-8), stratified by centre. Central randomisation will be performed using a secure, web-based, randomisation system. The allocation sequence will be generated by the study statistician using computer generated random numbers.,Treatment,None (Open Label),The study in conceived as open-label: the patients and all the health-care personnel will be aware of the assigned group.","gender:All,Min Age:18 Years,Max Age:N/A",No,210
NCT04315896,"Active, not recruiting","April 14, 2020","August 15, 2020","COVID-19,Severe Acute Respiratory Syndrome","Randomized,Parallel Assignment,Double blinded, randomized controlled trial,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Clinical practitioners and data analysts will remain blinded all through the study. Blinding will end in case the attending physician considers the patient should abandon the study or some of the exclusion/elimination criteria apply.","gender:All,Min Age:18 Years,Max Age:80 Years",No,500
NCT04480138,Recruiting,"August 11, 2020","January 30, 2021",Covid19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04462848,Not yet recruiting,August 2020,December 2024,Corona Virus Infection,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:1 Month,Max Age:17 Years",No,30
NCT04394104,Not yet recruiting,"May 27, 2020","May 31, 2020",Health Behavior,"Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04512079,Not yet recruiting,September 2020,June 2021,"COVID-19,SARS-CoV-2","Randomized,Parallel Assignment,Study participants will be randomized in a 1:1:1 fashion to 1 of 3 arms:
Prophylactic enoxaparin (40 mg SC QD; 30 mg SC QD for CrCl <30 mL/min)
Full-dose enoxaparin (1 mg/kg SC Q12h; 1 mg/kg SC QD for CrCl <30 mL/min)
Apixaban (5 mg Q12h; 2.5 mg Q12h for patients with at least two of three of age ≥80 years, weight ≤60 kg or serum creatinine ≥1.5 mg/dL),Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,3600
NCT04354792,Completed,"May 1, 2020","June 10, 2020",Immunologic Activity Alteration,"Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:25 Years,Max Age:60 Years",No,500
NCT04510402,Not yet recruiting,August 2020,April 2021,"Covid19,Povidone Iodine Adverse Reaction","Non-Randomized,Parallel Assignment,Fifty healthy volunteers to use single application or double application of PVP-I nasal swabs and assess for safety and tolerability,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,50
NCT04366752,Recruiting,"April 22, 2020","September 22, 2020","COVID-19,Pneumonia,ARDS,Hemostasis,Coagulation","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04566276,Not yet recruiting,January 2021,June 2021,"COVID-19 Vaccine,Safety Issues","Non-Randomized,Sequential Assignment,Healthy adults (age 18 to 55 years) and elderlies (age 65 to 75 years) will be enrolled sequentially in an ascending dose fashion (10 µg, 25 µg, 50 µg, and 100 µg).,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,96
NCT04333550,Recruiting,April 2020,March 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:3 Years,Max Age:99 Years",No,50
NCT04387643,Completed,"March 1, 2020","April 2, 2020",Covid-19,"Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:60 Years",No,52
NCT04482205,Completed,"March 16, 2020","May 31, 2020",Economic Burden,"Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,840
NCT04547634,Enrolling by invitation,"July 1, 2020",December 2020,"Cancer Metastatic,Cancer,Survivorship","Randomized,Crossover Assignment,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:65 Years",No,30
NCT04492202,Not yet recruiting,"August 1, 2020","December 10, 2020","COVID,Knowledge, Attitudes, Practice","Other,Other","sampling_method:Probability Sample,gender:All,Min Age:22 Years,Max Age:75 Years",No,200
NCT04357106,Recruiting,"April 13, 2020",August 2020,COVID-19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,10
NCT04325867,Recruiting,"March 31, 2020","October 1, 2020","Angina Pectoris,Acute Coronary Syndrome,Coronary Syndrome,Coronary Artery Disease,Angioplasty,Stent Restenosis,Hypertension,Heart Failure, Systolic,Depression, Anxiety,Covid-19,Isolation, Social","N/A,Single Group Assignment,All patients with severe cardiovascular disease benefit from this project,Health Services Research,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,200
NCT04427865,Not yet recruiting,July 2020,November 2020,COVID-19,"Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:65 Years",No,200
NCT04367402,Recruiting,"March 30, 2020",September 2020,COVID-19,"Case-Control,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,600
NCT04407390,Recruiting,"June 1, 2020","May 1, 2022",COVID,"Randomized,Parallel Assignment,Randomized double-blind case-control trial,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:70 Years,Max Age:N/A",No,100
NCT04365608,Recruiting,"March 20, 2020","May 20, 2020","Intubation Complication,Intubation; Difficult or Failed,Cardiac Arrest,Influenza,Safety Issues","Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,90
NCT04548544,Completed,"October 18, 2019","May 20, 2020",Healthy,"Randomized,Parallel Assignment,Basic Science,Single (Participant)","gender:All,Min Age:14 Years,Max Age:18 Years",No,21
NCT04339686,Recruiting,"April 20, 2020",November 2020,The Gold Standard for Current SARS CoV2 Detection is RT-PCR,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,56000
NCT04322123,"Active, not recruiting","April 1, 2020","August 30, 2020",Coronavirus Infections,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,630
NCT04348877,Not yet recruiting,"April 20, 2020",December 2020,Coronavirus Disease (COVID-19),"N/A,Single Group Assignment,Antibody-Rich Plasma from COVID-19 recovered patients,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,20
NCT04310228,Recruiting,"March 8, 2020",May 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:65 Years",No,150
NCT04357275,Recruiting,"March 13, 2020",March 2022,"Critical Illness,ARDS,Inflammatory Response,COVID-19,Circulatory Shock","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,10000
NCT04314232,Recruiting,"March 18, 2020","December 31, 2021","COVID,Coronavirus Infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04488588,Completed,"March 15, 2020","July 1, 2020","Covid19,Coronavirus Disease,SARS-CoV-2","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:36 Years,Max Age:63 Years",No,1064
NCT04412356,Recruiting,"June 4, 2020","February 1, 2021","Covid-19,ARDS,Tracheostomy Complication,Respiratory Insufficiency,Corona Virus Infection","Randomized,Parallel Assignment,Randomized, single blinded, controlled trial,Treatment,Single (Participant),Patients will be blinded to the randomization outcome.","gender:All,Min Age:18 Years,Max Age:N/A",No,180
NCT04564716,Recruiting,"September 28, 2020","April 10, 2021",Covid19,"Randomized,Parallel Assignment,Randomized double-blind placebo-controlled,Prevention,Double (Participant, Investigator),Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:60 Years",No,100
NCT04508777,Enrolling by invitation,"September 9, 2020",March 2021,Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,600
NCT04554979,Completed,"June 1, 2020","July 15, 2020","Covid19,Diarrhea","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,199
NCT04387656,Recruiting,"May 21, 2020","May 31, 2023","Asymptomatic COVID-19 Infection Laboratory-Confirmed,Hematopoietic and Lymphoid Cell Neoplasm,Malignant Solid Neoplasm,Symptomatic COVID-19 Infection Laboratory-Confirmed","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04386291,Recruiting,"May 25, 2020","January 30, 2022","Generalized Anxiety,Health Anxiety","Randomized,Parallel Assignment,Participants are randomly assigned to one of three treatment arms: Anxiety Reduction Training (A.R.T.), ART with Kundalini Yoga, ART with Meditation,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,360
NCT04343963,Recruiting,"April 4, 2020","April 30, 2021","COVID-19,SARS-CoV-2","Randomized,Parallel Assignment,Participants will receive pyridostigmine at a dose of 60 mg / day (or matching placebo), P.O. during a period of up to 14 days, until hospital discharge, death, mechanical ventilation, or increase in the SOFA scale ≥2 points.
The proposed dose is a safe dose according to the experience in myasthenia gravis and healthy people, as well as in at least three clinical studies in people living with HIV.
Participants will be double-blind 1: 1 randomized to receive pyridostigmine or placebo for up to 14 days.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,436
NCT04523571,Recruiting,"July 28, 2020",August 2021,SARS-CoV-2,"Randomized,Parallel Assignment,Prevention,Triple (Participant, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:85 Years",No,144
NCT04394026,Recruiting,"April 16, 2020","October 1, 2020","Viral Pneumonia,COVID","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,500
NCT04385004,Recruiting,"April 27, 2020",July 2020,Acute Respiratory Distress Syndrome,"Case-Only,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,320
NCT04527211,Not yet recruiting,"September 7, 2020","December 16, 2020","Covid19,Healthcare Worker Patient Transmission","Randomized,Parallel Assignment,It will be performed a randomized, multicenter, triple-masked, placebo-controlled clinical experiment to determine the relative risk of SARS COV-2 infection, seroconversion, and clinically presenting disease.,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Simple randomization will be done with a random number generator and masking will be maintained by concealing the allocation with opaque envelopes. The active medicine as the control will have the same presentation, color and taste, it will be differentiated by a pre-established code from the maker. This will maintain the concealment of patients, caregivers and evaluators. At the central level, only an intervention safety coordinator will know the assignment of each patient in case serious adverse events occur and the concealment needs to be lifted. The outcomes of interest will be obtained from the clinical history of the patients and through direct measurement in the follow-up visits.","gender:All,Min Age:18 Years,Max Age:N/A",No,550
NCT04407117,Completed,"March 23, 2017","April 19, 2020",Appendicitis,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,6000000
NCT04386460,Recruiting,"May 11, 2020","May 11, 2021","Nutrition Poor,Infection Viral,Oral Disease","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04347460,Recruiting,"March 27, 2020","August 31, 2020",COVID,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04406194,Completed,"May 14, 2020","June 19, 2020",Bioequivalence,"Randomized,Crossover Assignment,Other,None (Open Label)","gender:Male,Min Age:20 Years,Max Age:40 Years",No,30
NCT04453488,Not yet recruiting,"July 30, 2020",December 2020,"Covid-19,Sars-CoV2","Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,315
NCT04468217,Recruiting,"June 2, 2020","September 25, 2020","COVID,SARS-CoV2,Corona Virus Infection","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:75 Years",No,150
NCT04456153,Recruiting,"July 22, 2020",March 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04354779,Completed,"May 11, 2020","September 28, 2020","Severe Acute Respiratory Syndrome Coronavirus 2,SARS-CoV 2,Coronavirus Infection,Covid19","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:15 Years,Max Age:90 Years",No,3301
NCT04501796,Recruiting,August 2020,December 2021,COVID-19,"Randomized,Sequential Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double-Blind.","gender:All,Min Age:18 Years,Max Age:75 Years",No,30
NCT04560881,Recruiting,"September 16, 2020","December 1, 2021",COVID-19 Virus Infection,"Randomized,Parallel Assignment,Clinical trial conducted in randomized, double-blinded, placebo-controlled design.,Prevention,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:85 Years",No,3000
NCT04351568,Recruiting,"April 1, 2020",August 2020,Evaluating the Effect of Social Media Usage in Providing Healthcare Services During the Period of 19 Covid Pandemics,"Ecologic or Community,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:60 Years",No,874
NCT04329559,Recruiting,"March 30, 2020","June 29, 2021","COVID-19,Liver Cirrhosis","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04406558,Recruiting,"May 27, 2020",November 2020,"Psychological Adaptation,Psychology, Social","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:11 Years,Max Age:18 Years",No,400
NCT04569292,Recruiting,"January 1, 2020",August 2021,Covid19,"Case-Only,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,150
NCT04481646,Recruiting,"June 12, 2020",June 2025,Covid19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:16 Years,Max Age:N/A",No,630
NCT04474444,Recruiting,"March 23, 2019","March 23, 2021","Alcohol Use, Unspecified,Substance Use,Intoxication Alcohol,Emergencies,COVID-19 Pandemic,Treatment","Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,55000
NCT04411680,Recruiting,"August 18, 2020",March 2021,"COVID-19,Sars-CoV2","Randomized,Parallel Assignment,This Phase 2, randomized, open-label study will enroll approximately 60 patients with COVID-19 associated acute hypoxemia. It is a randomized 2:1 study to evaluate sargramostim treatment plus institutional standard of care compared to institutional standard of care alone.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04409184,Withdrawn,"August 14, 2020","August 14, 2020","COVID,Sars-CoV2","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04336787,Not yet recruiting,"April 12, 2020","June 10, 2020","Covid-19,Coronavirus Infection,Pregnancy Related","Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:45 Years",No,100
NCT04414124,Recruiting,"July 2, 2020",December 2020,Mild-to-moderate COVID-19,"Randomized,Parallel Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04393233,Recruiting,"April 23, 2020","May 23, 2020","Rheumatoid Arthritis,COVID","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04424134,Recruiting,"May 16, 2020","August 23, 2020",COVID 19,"Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04397328,Not yet recruiting,"May 19, 2020","April 30, 2021",COVID-19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:40 Years,Max Age:N/A",No,336
NCT04406038,"Active, not recruiting","May 27, 2020","October 28, 2020",COVID19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1038
NCT03648372,Recruiting,"October 1, 2018","October 6, 2021","Neoplasms,Lymphoma,Hematologic Neoplasms,Coronavirus Disease","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04384731,Recruiting,"May 29, 2020","January 30, 2021","COVID-19,ARDS, Human","Randomized,Parallel Assignment,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:100 Years",No,20
NCT04368260,Recruiting,"April 24, 2020","July 31, 2020",COVID19,"Non-Randomized,Parallel Assignment,The primary objective of this study is to determine whether the newly designed nasopharyngeal swabs perform acceptably compared to standard swabs.,Other,None (Open Label)","gender:All,Min Age:N/A,Max Age:99 Years",No,40
NCT04351139,Recruiting,"May 6, 2020","November 6, 2020","Gynecologic Cancer,Breast Neoplasm Female,Uterine Neoplasms,Ovarian Neoplasms,Uterine Cervical Neoplasms,Vulvar Neoplasms,Vaginal Neoplasms","Case-Control,Other","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:N/A",No,400
NCT04342208,Not yet recruiting,"April 10, 2020","July 1, 2020",Musculoskeletal Pain,"Case-Only,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:65 Years",No,500
NCT04350099,Not yet recruiting,"April 15, 2020","June 15, 2021",Emotionnal Distress; COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,200
NCT04438694,Recruiting,"June 1, 2020","December 31, 2021",COVID19,"Randomized,Single Group Assignment,This study is a prospective, single-institution, single-arm, study using a historical control group for comparison. Open label, 2 arms: SOC and SOC+CP,Treatment,None (Open Label)","gender:All,Min Age:21 Years,Max Age:70 Years",No,67
NCT04362865,Recruiting,"April 27, 2020","December 1, 2024",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04397562,"Active, not recruiting","April 29, 2020",April 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,204
NCT04529499,Recruiting,"August 20, 2020","January 31, 2021",Covid19,"Randomized,Parallel Assignment,780 patients are randomized into two treatment groups at a 1:1 ratio, so as to have approximately 390 patients in favipiravir + supportive care group and 390 patients in placebo + supportive care group.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),This is a prospective, interventional, multi-centre, phase III, randomized, double blind, placebo-controlled, parallel design trial to evaluate the efficacy, safety and tolerability of favipiravir as adjunct ('add on') to supportive care, in comparison to placebo with supportive care, in the acute treatment of patients who have tested positive for SARS-CoV-2 and presenting with moderate to severe COVID-19.","gender:All,Min Age:21 Years,Max Age:80 Years",No,780
NCT04479332,Not yet recruiting,"August 1, 2020","July 31, 2022","Corona Virus Infection,Critical Illness","Randomized,Sequential Assignment,Treatment,None (Open Label)","gender:All,Min Age:20 Years,Max Age:N/A",No,334
NCT04488796,Recruiting,"September 7, 2020",December 2020,Health Behaviour Change,"Randomized,Factorial Assignment,This will be a 2 (automated vs. choice of automation) by 3 (Opt-in, active choice or enhanced active choice) factorial design pilot randomized control trial,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,145
NCT04548492,Not yet recruiting,"September 14, 2020",January 2021,the Use of Modern Technology Applications in Home Isolation,"Case-Crossover,Prospective","sampling_method:Probability Sample,gender:All,Min Age:35 Years,Max Age:N/A",No,175
NCT04406090,Completed,"April 1, 2020","June 30, 2020","Ischemic Stroke,Covid 19","Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04324996,Recruiting,"March 21, 2020","September 30, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,90
NCT04359303,Not yet recruiting,July 2020,December 2020,COVID,"Randomized,Crossover Assignment,Control group with WHO recommended treatment. Treatment group with WHO recommended treatment + systemic ozone therapy.,Treatment,Double (Participant, Investigator),With a randomization table, nurses will treat the patients in treatment groups. Each patient will be in individual rooms.","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04471766,Enrolling by invitation,"July 20, 2020",November 2020,"COVID-19,Respiratory Illness","Randomized,Parallel Assignment,Prevention,Single (Outcomes Assessor)","gender:All,Min Age:10 Years,Max Age:N/A",No,66000
NCT04360759,Withdrawn,"May 1, 2020","June 30, 2021","Covid-19,HIV","Randomized,Parallel Assignment,Pragmatic, multi-centre, open label, randomised controlled trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04413006,Recruiting,"May 25, 2020","March 31, 2021",Chronic Pain,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,28
NCT04290858,Withdrawn,"March 1, 2020","February 1, 2022","Coronavirus Infections,Pneumonia, Viral,Dyspnea","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04351633,Completed,"April 23, 2020","April 30, 2020","Sars-CoV2,Osteoporosis","Family-Based,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,52
NCT04400019,Not yet recruiting,September 2020,"April 1, 2021","Sars-CoV2,Coronavirus Infection,Prevention & Control,Nursing Home,Hydroxychloroquine","Randomized,Parallel Assignment,Controlled, randomized, triple-blind cluster study.,Prevention,Double (Participant, Outcomes Assessor),The HCQ and the placebo will be manufactured by Laboratorios Rubio, blinded in similar containers for HCQ and placebo and will be stored in the pharmacy of the participating reference hospitals and will be distributed to the participating residences by the research technicians hired for the project.
A record of doses delivered and monitoring of doses consumed will be carried out. The containers must be wrapped in a disposable protective cover, which can be removed before entering the residences, in order to minimize the accidental transmission of the virus through this route.","gender:All,Min Age:18 Years,Max Age:N/A",No,1930
NCT04519372,"Active, not recruiting","April 1, 2020","March 31, 2021","Covid19,SARS-CoV-2","Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,4099
NCT04363489,Not yet recruiting,"August 1, 2020","September 30, 2020",Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04276896,Recruiting,"March 24, 2020","December 31, 2024",Pathogen Infection Covid-19 Infection,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:6 Months,Max Age:80 Years",No,100
NCT04446065,Not yet recruiting,"September 30, 2020","October 30, 2021","COVID-19,SARS-CoV2","Randomized,Parallel Assignment,The study will use 2 parallel groups in each center to compare the effects of an oral formulation of EGCG (Previfenon®, patent pending) with those of placebo (starch) in the prevention of respiratory disease caused by SARS-CoV-2 (COVID-19) in health care workers directly exposed to clinical care, daily contact, or traffic of individuals with suspected for COVID-19 during the epidemic outbreak.,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:25 Years,Max Age:N/A",No,524
NCT04383652,Recruiting,"May 6, 2020","June 30, 2021",COVID,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,200
NCT04568122,Not yet recruiting,September 2020,March 2021,Covid19,"N/A,Single Group Assignment,Enrollment is to a single group. Specific eligibility criteria apply depending on whether the participant is a hospitalized patient, in high-risk or infected population, or low-risk population,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,3015
NCT04377659,Recruiting,"May 1, 2020","May 1, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04458246,Recruiting,July 2020,June 2021,"Chronic Disease,Chronic Diseases in Adolescence,Chronic Disease of Immune System,Chronic Kidney Diseases","Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:10 Years,Max Age:19 Years",No,140
NCT04468958,Recruiting,"August 5, 2020",December 2020,"COVID-19,SARS-CoV2","Randomized,Sequential Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:60 Years",No,28
NCT04422873,Recruiting,"June 3, 2020","September 3, 2020","End Stage Renal Disease,Sars-CoV2","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04379258,Not yet recruiting,"May 11, 2020","May 30, 2020","COVID-19,Critical Illness,Effectiveness,Outcome, Fatal","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:99 Years",No,650
NCT04420468,Not yet recruiting,June 2020,December 2020,COVID-19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:17 Years",No,20
NCT04539262,Recruiting,"September 14, 2020",December 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,282
NCT04441918,Recruiting,"June 5, 2020","December 11, 2020",COVID-19; and High Infection Risk of SARS-CoV-2,"Randomized,Sequential Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:15 Years,Max Age:45 Years",No,40
NCT04389515,Recruiting,"May 14, 2020","September 30, 2020","COVID-19,Prenatal Care,Postoperative Care","Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:45 Years",No,75
NCT04341584,Not yet recruiting,April 2020,"December 31, 2020",Corona Virus Infection,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,240
NCT04513210,Not yet recruiting,"November 1, 2020","February 28, 2022",Covid19,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04381871,Not yet recruiting,"June 1, 2020","September 1, 2020",COVID 19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:5 Years,Max Age:90 Years",No,110
NCT04375644,Not yet recruiting,"May 11, 2020",August 2020,"Covid 19,Stress, Psychological","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1800
NCT04466839,Not yet recruiting,"July 2, 2020","December 18, 2020","Parkinson Disease,COVID","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,400
NCT04261517,Completed,"February 6, 2020","February 25, 2020","Pneumonia, Pneumocystis,Coronavirus,COVID-19","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04431284,Recruiting,"June 16, 2020","September 16, 2020",Feeding and Eating Disorders,"Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,46
NCT04354584,Recruiting,"April 6, 2020","April 6, 2021","COVID-19,Respiratory Failure","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04463004,Recruiting,"September 2, 2020",August 2021,"COVID-19,Sars-CoV2,Pneumonia","Randomized,Factorial Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04346940,Not yet recruiting,"August 10, 2020","November 30, 2020","Telerehabilitation,Elderly People,Social Isolation","Randomized,Parallel Assignment,Treatment,Single (Participant)","gender:All,Min Age:60 Years,Max Age:N/A",No,30
NCT04552366,Recruiting,"September 29, 2020","June 30, 2021",COVID-19,"Non-Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,144
NCT04535128,Recruiting,"March 24, 2020","March 30, 2021","Covid19,Thrombosis Embolism,DVT,Pulmonary Embolism,Myocardial Infarction,Stroke","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,10000
NCT04325893,Terminated,"April 1, 2020","June 18, 2020",Coronavirus,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,259
NCT04292340,Recruiting,"February 1, 2020","December 31, 2020",Coronavirus,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,15
NCT04345315,Recruiting,"March 27, 2020",March 2022,"COVID-19,SARS-CoV-2","Cohort,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04392232,Recruiting,"May 5, 2020","December 31, 2020","Coronavirus,COVID-19,Convalescent Plasma","N/A,Single Group Assignment,Non-Randomized, single arm study of convalescent plasma treatment of covid 19.,Treatment,None (Open Label)","gender:All,Min Age:16 Years,Max Age:N/A",N/A,100
NCT04391920,Recruiting,"August 28, 2020",October 2021,COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04432324,Not yet recruiting,June 2020,December 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04524156,Not yet recruiting,"October 4, 2020","May 4, 2023","COVID,Acute Respiratory Distress Syndrome,Endothelial Dysfunction","N/A,Single Group Assignment,Basic Science,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04346056,Recruiting,"April 14, 2020","December 1, 2020","Coronavirus Disease (COVID-19),COVID-19","Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:1 Year,Max Age:80 Years",No,500
NCT04363775,Completed,"January 20, 2020","February 25, 2020","Tracheal Intubation,Infection,Projection","Randomized,Crossover Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,35
NCT04280588,Recruiting,"February 22, 2020","July 1, 2020",Coronavirus Disease (COVID-19),"Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,30
NCT04408131,Recruiting,"May 28, 2020","January 27, 2021",Homeless,"N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04487210,Not yet recruiting,"September 15, 2020","September 30, 2021",COVID-19,"Non-Randomized,Sequential Assignment,Prevention,None (Open Label)","gender:All,Min Age:20 Years,Max Age:50 Years",No,45
NCT04353154,Not yet recruiting,"April 15, 2020","February 28, 2021",COVID,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04383730,Recruiting,"June 26, 2020","December 31, 2020","Critically Illness,Sedation,Invasive Mechanical Ventilation,Acute Respiratory Distress Syndrome","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04433910,Recruiting,June 2020,February 2021,COVID-19,"Randomized,Crossover Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,106
NCT04327180,Recruiting,"March 30, 2020",September 2021,"Infection Viral,Coronavirus,ARDS,Pneumonia","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04445272,Recruiting,"May 22, 2020","August 22, 2020",COVID-19,"N/A,Single Group Assignment,Phase II, one-arm, open label, multicentre study,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04480034,Not yet recruiting,"July 15, 2020","May 30, 2021","Bariatric Surgery Candidate,Covid19,Complication of Surgical Procedure,Pneumonia, Viral,Viral Infection,Obesity, Morbid,Safety Issues,Readmission","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:60 Years",No,1600
NCT04455347,Recruiting,"June 15, 2020",June 2022,COVID-19 Infection,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:20 Years",No,80
NCT04414319,Recruiting,"April 15, 2020","April 15, 2023",SARS-CoV 2,"Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:70 Years,Max Age:N/A",No,350
NCT04367636,Not yet recruiting,"April 20, 2020",August 2020,"Rumination,Anxiety,Stress,Depressive Symptoms","Randomized,Parallel Assignment,Supportive Care,Single (Participant)","gender:All,Min Age:18 Years,Max Age:65 Years",No,100
NCT04412785,Recruiting,"June 22, 2020",December 2020,COVID-19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04335084,Recruiting,"June 22, 2020",September 2021,"COVID-19,Coronavirus Infection,Sars-CoV2,Corona Virus Infection,COVID,Coronavirus,Coronavirus-19,Coronavirus 19","Randomized,Single Group Assignment,This study will focus on medical workers who at elevated risk of COVID-19 due to exposure to positive patients in the Emergency Department or Intensive Care Unit,Prevention,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,600
NCT04366154,Recruiting,"April 15, 2020",December 2020,"COVID-19,Cancer","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,385
NCT04420637,Enrolling by invitation,"June 15, 2020",December 2021,COVID,"Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1000
NCT04467840,Recruiting,"August 21, 2020",February 2021,"COVID-19,Lung Infection","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:80 Years",No,270
NCT04537650,Not yet recruiting,"September 1, 2020","December 31, 2021",Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,75
NCT04371965,Recruiting,"September 1, 2020","December 1, 2020",COVID-19,"Randomized,Parallel Assignment,Randomized controlled open label trial, parallel design,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,24
NCT04371510,Recruiting,"April 22, 2020","February 22, 2021",COVID-19 by SARS-CoV-2 Infection,"N/A,Single Group Assignment,PredictCOVID-D study. Covid-19 chronic haemodialysis patients with moderate symptoms,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:85 Years",No,115
NCT04560530,Completed,"March 1, 2020","September 1, 2020",Covid19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,76
NCT04433754,Completed,"March 1, 2020","June 12, 2020",Pancreatitis,"Case-Control,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04388618,Recruiting,"June 15, 2020","December 31, 2020","Anosmia,Ageusia,Covid19,Corona Virus Infection","Case-Control,Prospective","sampling_method:Probability Sample,gender:All,Min Age:12 Years,Max Age:65 Years",No,250
NCT04421664,Terminated,"March 25, 2020","August 17, 2020","Corona Virus Infection,SARS-CoV Infection,Coronavirus","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,70
NCT04370834,Suspended,"May 28, 2020","April 1, 2022","Hematopoietic and Lymphoid Cell Neoplasm,Malignant Solid Neoplasm,Pneumonia,Pneumonitis,Severe Acute Respiratory Distress Syndrome,Symptomatic COVID-19 Infection Laboratory-Confirmed","N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:2 Years,Max Age:N/A",N/A,217
NCT04274322,"Active, not recruiting","February 19, 2020",July 2020,"Critically Ill,Coronavirus Infections","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,117
NCT04361526,Recruiting,"April 17, 2020",July 2020,"Coronavirus Infection,Acute Respiratory Distress Syndrome,COVID","Randomized,Parallel Assignment,This is a two-branch randomized, controlled, uni-center study. Eligible patients will be randomly assigned in a 1:1 ratio to receive cytokine filtration plus standard intensive care, or standard intensive care alone,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04363671,Not yet recruiting,May 2020,December 2020,"Remote Consultation,Covid-19","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:11 Years,Max Age:N/A",No,30
NCT04422561,Completed,"May 31, 2020","July 27, 2020",COVID,"Randomized,Sequential Assignment,Prevention,None (Open Label)","gender:All,Min Age:16 Years,Max Age:70 Years",No,340
NCT04385849,Not yet recruiting,"June 1, 2020","July 11, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04479150,Recruiting,"March 1, 2020","August 31, 2020","Covid19,Surgery--Complications","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,3000
NCT04366882,Recruiting,"April 14, 2020",December 2020,COVID-19,"N/A,Single Group Assignment,Health Services Research,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,45
NCT04355481,Recruiting,"April 17, 2020","December 17, 2020","Covid-19,Viral Infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04526769,Not yet recruiting,September 2020,April 2021,"COVID,COVID-19,Corona Virus Infection,SARS-CoV-2","Case-Only,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04329507,Recruiting,"March 25, 2020","March 25, 2021","COVID-19,Respiratory Disease","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04488510,"Active, not recruiting","May 6, 2020","November 30, 2020","Covid19,Ventilator Associated Pneumonia,Nosocomial Pneumonia","Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04449731,Recruiting,"March 20, 2020","June 30, 2021",COVID-19,"Ecologic or Community,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,30000
NCT04320615,Completed,"April 3, 2020","July 28, 2020",COVID-19 Pneumonia,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,450
NCT04557046,Recruiting,"June 26, 2020","December 31, 2020",Covid19,"Non-Randomized,Parallel Assignment,Subject are asked to provide nasal swab or nasopharyngeal swab and saliva samples,Diagnostic,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,400
NCT04332107,Recruiting,"May 22, 2020","September 30, 2021","COVID-19,SARS-CoV-2","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,2271
NCT04331509,Recruiting,"March 23, 2020","March 23, 2022",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,10000000
NCT04350073,Recruiting,"April 20, 2020","December 1, 2020",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04324073,"Active, not recruiting","March 27, 2020","December 31, 2021",Corona Virus Infection,"Randomized,Parallel Assignment,Bayesian open labelled randomized clinical trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,239
NCT04346342,Completed,"March 6, 2020","September 1, 2020","COVID,Mechanical Ventilation,Acute Respiratory Failure","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1122
NCT04410718,Recruiting,"April 20, 2020","November 30, 2020","Diabetes Mellitus,Diabetes Mellitus, Type 2,Diabetes Mellitus, Type 1,COVID","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04402944,Not yet recruiting,"June 18, 2020","December 31, 2021",COVID,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:3 Years,Max Age:N/A",No,60
NCT04344834,Not yet recruiting,May 2020,October 2020,Mental Health Issue,"Ecologic or Community,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,300
NCT04364815,Not yet recruiting,May 2020,May 2021,COVID-19,"Randomized,Parallel Assignment,Randomized, assessor- and patient- blinded, placebo controlled, parallel group trial,Prevention,Double (Participant, Outcomes Assessor),Randomized allocation concealment
Computer-generated random numbers for two groups will be used by a third party to create an allocation list for participants
The pharmacist will prepare the test medication in sequentially numbered packages
The third party will be contacted upon enrollment of a participant for the assigned group
Blinding
Placebo tablets will have the same appearance as the HCQ tablets
The pharmacist will prepare the test medications in sequentially numbered packages
Blinding of the outcome assessor will be achieved by using numerical codes on the Case Record Form of each patient with no indication of the group assignment on the Case Record Forms
Laboratory specimens, ECG strip, and RT-PCR test specimens will be labeled with the numerical code of the participant and test number","gender:All,Min Age:18 Years,Max Age:59 Years",No,960
NCT04528927,Withdrawn,"May 15, 2020","July 15, 2020","COVID 19,Patients Hospitalized","Randomized,Parallel Assignment,Parallel assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,0
NCT04495764,"Active, not recruiting","July 20, 2020",March 2021,"SARS-CoV-2 Infection,Anti-SARS-CoV-2 Infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,2504
NCT04394169,Recruiting,"May 25, 2020","March 25, 2021","Post ICU Syndrome,Chronic Pain,Covid-19","Randomized,Parallel Assignment,Randomized, controlled, single-blind, and single-center clinical trial that will include patients who have been admitted to intensive care of our hospital due to COVID-19 disease.,Prevention,Single (Investigator),Visits 1,2, and 3 will be carried out by an investigator with sufficient training in questionnaires. This investigator will not participate on the intervention or the evaluation of the results.
The intervention will be performed by two researchers (Pain Physician and psychologist). This researcher will not participate in the questionnaire and basal data collection visits or results analysis.
Researchers who analyze the results will not participate in the questionnaire and basal data collection or program intervention.","gender:All,Min Age:18 Years,Max Age:N/A",No,102
NCT04390178,"Active, not recruiting","April 10, 2020",December 2020,COVID-19,"N/A,Single Group Assignment,An open, non-randomised controlled, clinical trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,10
NCT04375176,Recruiting,"April 27, 2020","October 31, 2020","COVID-19,Severe Acute Respiratory Syndrome Coronavirus 2,Immunomodulation","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04551898,Not yet recruiting,"October 30, 2020","February 28, 2021",Covid19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:65 Years",No,180
NCT04355624,Recruiting,"April 15, 2020","July 30, 2020","COVID,Kidney Injury","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04338932,Completed,"April 17, 2020","May 15, 2020","COVID-19,Deep Vein Thrombosis (DVT)/Thrombophlebitis","Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,12
NCT04535700,Not yet recruiting,"September 7, 2020","April 10, 2021",Type 2 Diabetes,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,76
NCT04365309,Enrolling by invitation,"February 10, 2020",June 2020,"Novel Coronavirus Pneumonia,Aspirin,Treatment","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:85 Years",No,128
NCT04425629,Recruiting,"June 16, 2020","December 19, 2020",COVID-19,"Randomized,Parallel Assignment,Phase 1/Phase 2/Phase 3,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,2104
NCT04561193,Recruiting,"May 30, 2020",May 2021,COVID-19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04389580,Not yet recruiting,June 2020,September 2020,COVID-19,"Randomized,Sequential Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,160
NCT04433988,Not yet recruiting,"December 13, 2020","December 30, 2020",COVID,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:60 Years",No,200
NCT04497415,Not yet recruiting,"August 30, 2020","January 30, 2021","Brief Video-based Intervention,Non Intervention Control","Randomized,Parallel Assignment,Health Services Research,Single (Participant)","gender:All,Min Age:18 Years,Max Age:80 Years",No,1200
NCT04412772,Recruiting,"June 1, 2020","December 31, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:95 Years",No,300
NCT04405271,Not yet recruiting,"July 31, 2020","November 15, 2020","Healthcare Workers,COVID-19,SARS-CoV 2","Randomized,Parallel Assignment,Randomized (1:1), double-blind, placebo-controlled clinical trial,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),The treatment will be the same in both arms: 1 tablet per day will be administered for a total of 12 weeks. Placebo and the active principle will be indistinguishable.","gender:All,Min Age:18 Years,Max Age:N/A",No,1378
NCT04331808,"Active, not recruiting","March 30, 2020","December 31, 2021",Corona Virus Infection,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,228
NCT04363216,Not yet recruiting,May 2020,May 2021,COVID-19,"Randomized,Sequential Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,66
NCT04385160,Recruiting,"May 13, 2020","September 1, 2020","Myeloproliferative Neoplasm,COVID","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04415359,Recruiting,"May 20, 2020",July 2020,Covid-19,"Case-Only,Other","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:43 Years",No,700
NCT04420312,Completed,"March 1, 2020","April 20, 2020","Pulmonary Embolism,Covid-19","Case-Control,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1024
NCT04365166,Recruiting,"April 21, 2020","April 21, 2022","Respiratory Tract Infections,Respiratory Tract Disease","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04270383,Not yet recruiting,"February 15, 2020","December 31, 2020",2019-nCoV,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:18 Years",No,500
NCT04514003,Recruiting,"July 1, 2020","December 31, 2035",Covid19,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:85 Years",No,5000
NCT04385810,Recruiting,"April 27, 2020",October 2020,"Covid19,Sars-CoV2","N/A,Single Group Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04394000,Completed,"May 4, 2020","May 15, 2020","COVID19,Thromboembolism","Cohort,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,72
NCT04558463,Recruiting,"April 16, 2020","October 30, 2020",Covid19,"Randomized,Parallel Assignment,Subjects will be divided into two groups: favipiravir and oseltamivir as adjuvant therapy in addition to standard therapy,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,100
NCT04383717,Not yet recruiting,"May 5, 2020","October 30, 2020",Respiratory Tract Infections,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:6 Years,Max Age:90 Years",No,60
NCT04357977,Not yet recruiting,April 2020,December 2020,"Coronavirus,COVID","Ecologic or Community,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04524520,Recruiting,"May 5, 2020","May 8, 2022",Exploring Risk Assessment and Recovery From COVID-19 Infection in Hospitalised Patients,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04529408,Recruiting,"August 26, 2020","August 26, 2020","Covid19,Pulmonary Disease","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04368923,"Active, not recruiting","March 15, 2020","June 23, 2020",Covid 19,"Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:21 Years,Max Age:40 Years",No,60
NCT04558749,Not yet recruiting,October 2020,June 2021,Covid19,"Other,Cross-Sectional","sampling_method:Probability Sample,gender:Female,Min Age:N/A,Max Age:N/A",No,150
NCT04370938,Recruiting,"April 29, 2020","October 29, 2020","Perceived Organizational Support, Anxiety, Burnout","Randomized,Parallel Assignment,A longitudinal survey-based research study investigating the domains of perceived organizational support, anxiety, and burnout will take place. Healthcare providers with patient-care contact will be asked to fill out these surveys once every 30 days over a period of 6 months. After the first survey is complete, 20% of participants will be randomized to watch a 1-hour long video discussing coping strategies for stress related to the COVID-19 pandemic.,Other,Single (Outcomes Assessor),Individuals responsible for analyzing survey data (including that which was administered after the intervention), will be masked with regard to whether the participant received the intervention.","gender:All,Min Age:18 Years,Max Age:N/A",No,250
NCT04503057,Recruiting,"May 1, 2020","May 1, 2024","Covid19,ARDS, Human,ALI","Case-Control,Prospective","sampling_method:Probability Sample,gender:All,Min Age:16 Years,Max Age:90 Years",No,300
NCT04507282,Completed,"May 15, 2020","July 15, 2020",COVID-19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04341922,"Active, not recruiting","May 9, 2020","September 10, 2021",Dysfunctional Worry,"Randomized,Crossover Assignment,Treatment,None (Open Label)","gender:All,Min Age:16 Years,Max Age:N/A",No,670
NCT04519424,Not yet recruiting,September 2020,May 2021,Coronavirus Disease 2019 (COVID-19),"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,124
NCT04351581,Recruiting,"May 18, 2020",December 2020,Covid-19,"Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,215
NCT04347915,Recruiting,"May 6, 2020","December 31, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Single (Participant)","gender:All,Min Age:19 Years,Max Age:N/A",No,60
NCT04401423,Recruiting,August 2020,December 2021,COVID-19,"Randomized,Parallel Assignment,Double-blinded, placebo-control, randomized clinical trial,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04522128,Recruiting,"May 22, 2020","December 31, 2022","COVID,Quality of Life,Behavior,Social Isolation","Randomized,Parallel Assignment,Other,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,969
NCT04342182,Recruiting,"April 8, 2020","July 1, 2020",COVID-19,"Randomized,Parallel Assignment,This trial is a randomized comparative trial. Patients will be randomized between the infusion of 300mL of convP versus the standard of care.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,426
NCT04359901,Recruiting,"April 10, 2020",April 2023,COVID,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04381858,Recruiting,"May 6, 2020","September 30, 2020",COVID-19 Pneumonia,"Randomized,Parallel Assignment,Treatment,Double (Participant, Outcomes Assessor)","gender:All,Min Age:16 Years,Max Age:90 Years",No,500
NCT04330495,Not yet recruiting,"April 6, 2020","November 6, 2020","COVID 19,Immunomediated Inflammatory Disease in Treatment With Biological Agents and / or Jak Inhibitors","Randomized,Parallel Assignment,Randomized, controlled, double-blind clinical trial,Prevention,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:75 Years",No,800
NCT04375397,Recruiting,"June 6, 2020","April 16, 2021",CoronaVirus Induced Disease-2019 (COVID-19),"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,46
NCT04441385,Recruiting,"June 26, 2020","December 20, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04499300,Recruiting,"June 9, 2020",December 2020,Covid19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:90 Years,Max Age:N/A",No,50
NCT04491214,Recruiting,"July 24, 2020","July 27, 2021","Covid19,Follow up,Rehabilitation","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,131
NCT04363268,Recruiting,"April 20, 2020","October 1, 2031","Coronavirus,COVID,COVID-19,COVID19,Corona Virus Infection,Coronavirus Infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000000
NCT04568707,Not yet recruiting,"October 15, 2020","October 15, 2022","Covid19,Neurologic Manifestations,Psychiatric Manifestations","N/A,Single Group Assignment,Basic Science,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04535674,Not yet recruiting,September 2020,May 2021,"COVID-19 Induced Pneumonia,Covid19","Randomized,Parallel Assignment,Asunercept/APG101 will be tested in three parallel intervention arms and compared with Standard of Care (SoC). The study will compare treatment efficacy of SoC to that of weekly intravenous infusions of Asunercept at three different doses. Patients will be randomised into four groups.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04379089,Recruiting,"April 29, 2020","December 31, 2022","COVID,Neurologic Manifestations","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:17 Years",No,500
NCT04514302,Not yet recruiting,"October 20, 2020","June 20, 2021",COVID-19,"Randomized,Parallel Assignment,Parallel,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double Blind","gender:All,Min Age:18 Years,Max Age:N/A",No,51
NCT04563247,"Active, not recruiting","July 1, 2020","October 30, 2020",Covid19,"Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:20 Years,Max Age:60 Years",No,700
NCT04452942,Not yet recruiting,July 2020,April 2021,COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04292730,Completed,"March 15, 2020","June 26, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:12 Years,Max Age:N/A",Yes,1113
NCT04397705,Not yet recruiting,June 2020,October 2020,"COVID,Oncology,Haematological Malignancy","N/A,Single Group Assignment,Single arm open label study.,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04497324,Not yet recruiting,"August 20, 2020","December 31, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04361903,Not yet recruiting,"April 25, 2020","May 31, 2020",Severe Acute Respiratory Syndrome Coronavirus 2,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,13
NCT04516668,Not yet recruiting,November 2020,November 2020,Post Partum Depression,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,250
NCT04395664,Completed,"April 16, 2020","September 1, 2020",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04366024,Recruiting,"January 17, 2020","December 31, 2021","COVID-19 Disease,Nomogram Model","Case-Only,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04372199,Recruiting,"April 29, 2020","May 27, 2020","COVID,Pneumonia","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,248
NCT04425252,Recruiting,"June 25, 2020",April 2021,COVID-19,"Randomized,Parallel Assignment,Randomized 1:2 to standard of care (SOC) alone or SOC + brequinar,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,24
NCT04414657,Recruiting,"April 9, 2020","April 30, 2022",COVID19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04397822,Recruiting,"April 16, 2020",April 2021,COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04423289,Completed,"March 31, 2020","May 18, 2020",Face-to-face Reconsultation to Emergency Room,"Randomized,Parallel Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04427631,Not yet recruiting,"June 22, 2020","June 1, 2021","Hearing Impaired Children,Glue Ear,Hearing Loss, Conductive","N/A,Single Group Assignment,single arm study offering all children with glue ear currently waiting on grommet operation lists, an invitation to be involved in this research study for hearing support (bone conduction headphones, a microphone and an app which can be delivered remotely),Treatment,None (Open Label),It is too difficult to blind the assessor in thsi instance.","gender:All,Min Age:3 Years,Max Age:11 Years",No,20
NCT04352582,Recruiting,"April 14, 2020","April 30, 2020",COVID-19,"Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1000
NCT04476992,"Active, not recruiting","July 24, 2020","September 17, 2021","Hypoxemia,Pneumonia, Viral,Coronavirus Infection","Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04505709,Enrolling by invitation,"August 1, 2020","August 1, 2021",Covid19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Months,Max Age:N/A",No,1000
NCT04543760,Recruiting,"October 1, 2020",May 2021,Covid19,"Randomized,Crossover Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,18
NCT04397237,Not yet recruiting,May 2020,December 2020,"COVID-19,Systemic Lupus Erythematosus,Sjogren's Syndrome,Axial Spondyloarthritis,Rheumatoid Arthritis,Giant Cell Arteritis","Case-Control,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,3600
NCT04394793,"Active, not recruiting","June 13, 2020",September 2020,"COVID-19,Pneumonia","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,10
NCT04388709,Not yet recruiting,September 2020,May 2021,SARS-CoV-2,"Randomized,Parallel Assignment,Cohort A: Peginterferon lambda-1a (Lambda) 180mcg subcutaneous injection once Cohort B: Best supportive care,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,66
NCT04292327,"Active, not recruiting","January 1, 2020","July 31, 2020",Pneumonia Caused by Human Coronavirus,"Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:75 Years",No,400
NCT04470999,Recruiting,"April 15, 2020","December 31, 2020","Covid19,SARS-CoV-2","N/A,Single Group Assignment,Basic Science,None (Open Label)","gender:All,Min Age:18 Years,Max Age:60 Years",No,25
NCT04522817,Not yet recruiting,October 2020,May 2021,Covid-19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,12
NCT04361461,Withdrawn,"April 30, 2020","November 4, 2020","Coronavirus Infections,SARS-CoV 2,SARS (Severe Acute Respiratory Syndrome),Pulmonary Disease","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04368988,Recruiting,"May 25, 2020","November 18, 2021",COVID-19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:84 Years",No,1631
NCT04345536,Recruiting,"March 15, 2020","May 1, 2021",COVID-19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,400
NCT04280913,Withdrawn,"February 22, 2020","March 31, 2020",Coronavirus Disease 2019,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,0
NCT04392219,Completed,"April 10, 2020","August 11, 2020",Coronavirus,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:60 Years",No,130
NCT04357639,Recruiting,"May 28, 2020","July 31, 2021",HIV Patients,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1040
NCT04414371,Recruiting,"May 20, 2020","December 31, 2020","Stress,Anxiety,Depression,Resilience,Wellbeing,Mood","Randomized,Crossover Assignment,Randomized waitlist control cross over,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04385186,Not yet recruiting,"June 20, 2020","December 30, 2020","Infections, Coronavirus","Randomized,Parallel Assignment,MULTICENTER, CONTROLLED, RANDOMIZED, SIMPLE BLIND, CLINICAL TRIAL,Treatment,Single (Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04257656,Terminated,"February 6, 2020","April 10, 2020","COVID-19,Remdesivir,SARS-CoV-2","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,237
NCT04325672,Withdrawn,"April 1, 2020","December 31, 2022",Coronavirus,"N/A,Single Group Assignment,Basic Science,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04331470,Recruiting,"April 4, 2020","May 20, 2020",COVID-19,"Randomized,Parallel Assignment,Study is two armed , double blind, parallel, randomized clinical trial.,Treatment,Double (Participant, Outcomes Assessor),All of the research team will be blind about the groups of study and position of patients in each group except of physician and main researcher. Files of patients which will be numbered using a random number table will be sent for analyzer of the study.Information about position of patients in the groups is masked from research team. Outcomes Assessor will receive the information of patients without any name in the file. Just when statistical analysis would be finished information of groups will be revealed.","gender:All,Min Age:15 Years,Max Age:100 Years",No,30
NCT04449718,Recruiting,"June 1, 2020","November 30, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04395768,Recruiting,"September 9, 2020","December 31, 2021",COVID19,"Randomized,Parallel Assignment,randomized investigator-blinded controlled,Treatment,Double (Investigator, Outcomes Assessor),Participants not blinded as they will know whether they are receiving the comparator vitamin c (either IVC) or oral in addition to treatments in the control group; outcomes assessor / investigators conducting statistical analysis will be blinded","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04393311,Not yet recruiting,November 2020,May 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,160
NCT04292899,Completed,"March 6, 2020","June 30, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:12 Years,Max Age:N/A",Yes,4891
NCT04422275,Not yet recruiting,"June 1, 2021","December 31, 2023",Anosmia,"Randomized,Factorial Assignment,2 x 2 factorial design,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Blinded","gender:All,Min Age:18 Years,Max Age:85 Years",No,200
NCT04304053,Completed,"March 18, 2020","June 15, 2020",COVID-19,"Randomized,Parallel Assignment,Primary study: Cluster-randomized clinical trial of Covid-19 contacts
Secondary study: Randomized clinical trial of Covid-19 cases,Prevention,None (Open Label),Open label","gender:All,Min Age:18 Years,Max Age:N/A",No,2300
NCT04404062,"Active, not recruiting","March 16, 2020",August 2020,COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:70 Years",No,500
NCT04288713,Available,N/A,N/A,N/A,N/A,"gender:All,Min Age:18 Years,Max Age:N/A",No,N/A
NCT04407182,Recruiting,"May 4, 2020","August 7, 2020","Covid-19,Sars-CoV2,Diabete Mellitus,Cardiopathy,Pulmonary Disease,Renal Disease,Liver Diseases","Randomized,Parallel Assignment,Supportive Care,Triple (Participant, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:70 Years",No,80
NCT04490824,Recruiting,"October 1, 2020","November 30, 2020",Covid19,"Randomized,Sequential Assignment,Participants will be sequentially assigned to receive KELEA activated or KELEA depleted water,Treatment,Single (Participant),The participant will not be informed as to whether the item that is first received is KELEA emitting or inactive. If requested an active item will be sent following receipt of the post inhalation results.","gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04335786,Recruiting,"April 17, 2020",December 2021,"Acute Respiratory Distress Syndrome,SARS-CoV-2,COVID,COVID-19,Severe Acute Respiratory Syndrome","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,651
NCT04522492,Enrolling by invitation,"August 11, 2020",March 2021,Skin Picking,"Randomized,Parallel Assignment,randomized clinical trial with the intervention consisting of cognitive behavioral therapy in an online setting, and the control consisting of an active control group (guidelines about strategies to improve quality of life).,Treatment,Single (Outcomes Assessor),Two assessors will evaluate patients before and after the intervention, thru an online consultation and application of instruments to assess symptoms. The assessors will be blinded about the intervention received by the patient.","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04308668,Completed,"March 17, 2020","May 20, 2020","Corona Virus Infection,Acute Respiratory Distress Syndrome,SARS-CoV Infection,Coronavirus,Coronavirus Infections","Randomized,Parallel Assignment,Asymptomatic participants are randomized and analyzed separate from symptomatic participants.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,1309
NCT04370262,Recruiting,"April 7, 2020","April 7, 2021",COVID-19,"Randomized,Parallel Assignment,Randomized, Double-Blind Comparative Trial,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,942
NCT04435457,Not yet recruiting,August 2020,October 2020,"SARS-CoV 2,SARS Pneumonia,COVID-19,SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere,Cardiac Complication","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,70
NCT04393974,Recruiting,"March 24, 2020","March 24, 2022","Cancer,Sars-CoV2","Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04568850,"Active, not recruiting","July 1, 2020","November 30, 2020",Covid19,"Case-Only,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,50
NCT04354714,Withdrawn,"June 30, 2020","December 31, 2021",COVID-19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04386668,Terminated,"May 26, 2020","August 31, 2020",COVID19,"Randomized,Parallel Assignment,Other,Double (Participant, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04531111,Recruiting,"July 7, 2020",August 2020,"Type 1 Diabetes,Covid19","Case-Only,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:2 Years,Max Age:18 Years",No,150
NCT04412291,Recruiting,"June 11, 2020",February 2021,Covid-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04398043,Not yet recruiting,"May 15, 2020","July 30, 2020","rt PCR,COVID,Personal Protective Equipment PPE,SARS-CoV 2,Health Personnel Attitude,Virus Diseases","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:16 Years,Max Age:N/A",No,16
NCT04385199,Recruiting,"May 4, 2020","August 1, 2020","Coronavirus Infection,Coronavirus,COVID","Randomized,Parallel Assignment,Randomized control trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,30
NCT04391881,Recruiting,"May 30, 2020","August 30, 2020",Oral Health and COVID 19,"Other,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:60 Years",No,500
NCT04574869,Not yet recruiting,October 2020,July 2021,"Acute Lung Injury,ALI,COVID-19","Randomized,Sequential Assignment,Study intervention, RLS-0071 or placebo, will be administered as an IV infusion over 30 minutes (± 10 minutes).
The following dose groups are planned:
Part A (Single-Ascending Dose):
Cohort 1: low dose (single infusion) vs. placebo
Cohort 2: high dose (single infusion) vs. placebo
Part B (Multiple-Ascending Dose):
Cohort 3: low dose administered q8 hours (± 1 hour) vs. placebo for 3 days (9 doses)
Cohort 4: high dose administered q8 hours (± 1 hour) vs. placebo for 3 days (9 doses),Treatment,Double (Participant, Investigator),This study is a double-blinded and randomized study. Pharmacy staff will mask infusion bags and lines to maintain the study blind.","gender:All,Min Age:18 Years,Max Age:69 Years",No,42
NCT04366167,Recruiting,"April 18, 2020","December 31, 2021","Cardiac Surgery,COVID","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:120 Years",No,100
NCT04407559,"Active, not recruiting","May 1, 2020","September 30, 2020","COVID-19,Rheumatoid Arthritis","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,216
NCT04568135,Not yet recruiting,"September 18, 2020","December 31, 2021",Covid19,"Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,1000
NCT04410107,Recruiting,"May 15, 2020","August 2, 2022","COVID-19,SARS-CoV-2 Infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,134
NCT04256395,Completed,"February 1, 2020","July 1, 2020",Susceptibility to Viral and Mycobacterial Infection,"Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,102456
NCT04323787,Recruiting,"March 30, 2020","April 30, 2021",Coronavirus,"Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,50000
NCT04425538,Recruiting,"June 1, 2020",December 2020,COVID-19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,17
NCT04430322,Recruiting,"March 1, 2020","June 30, 2021",COVID,"Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,330
NCT04426279,Recruiting,"August 18, 2020",December 2020,"Sars-CoV2,Rheumatoid Arthritis,Rheumatic Diseases","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1500
NCT04373707,Recruiting,"May 13, 2020",October 2020,"COVID,Thrombosis,Pulmonary Embolism,Deep Vein Thrombosis","Randomized,Parallel Assignment,Multicenter randomized (1:1) controlled open-label trial, stratified on disease severity (admission to ICU or not),Prevention,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,602
NCT04452708,Recruiting,"June 11, 2020","June 10, 2021",Respiratory Failure,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,15
NCT04320238,Recruiting,"January 21, 2020",June 2020,2019 Novel Coronavirus Infection,"Non-Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:65 Years",No,2944
NCT04406844,Recruiting,"May 9, 2020","June 30, 2021",Oncology Patients,"Cohort,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:12 Years,Max Age:98 Years",No,150
NCT04359706,Recruiting,"May 8, 2020",September 2020,Sars-CoV2,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04353180,Not yet recruiting,September 2020,November 2020,COVID19,"Randomized,Parallel Assignment,Patients and method :
This study will performed on 1000 patients tested positive for the presence of COVID-19 RNA by RT-PCR kit for RNA detection will randomly divided into 3 equal groups,Treatment,None (Open Label),Patients
This study will performed on 1000 patients tested positive for the presence of COVID-19 RNA by RT-PCR kit for RNA detection will randomly divided into 3 equal groups","gender:All,Min Age:18 Years,Max Age:80 Years",No,1000
NCT04563208,Not yet recruiting,December 2020,March 2021,"Covid19,SARS-CoV Infection","Randomized,Parallel Assignment,Treatment,Double (Participant, Care Provider),Double-blind","gender:All,Min Age:18 Years,Max Age:75 Years",No,40
NCT04313946,Recruiting,"March 18, 2020","August 18, 2020","COVID-19,Pneumonia, Viral,Influenza With Pneumonia,Flu Symptom,Flu Like Illness,Pneumonia, Interstitial,Pneumonia, Ventilator-Associated,Pneumonia Atypical","Ecologic or Community,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,200
NCT04363099,Recruiting,"March 1, 2020","December 31, 2020",Covid-19,"Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:99 Years",No,1000
NCT04561063,Not yet recruiting,December 2020,July 2021,"Covid19,SARS-CoV Infection","Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:99 Years",No,1950
NCT04417270,Recruiting,"June 12, 2020","October 31, 2020",Diabetes Mellitus,"Non-Randomized,Crossover Assignment,Patients will use the Freestyle 14 day CGM reader or their phone to check their glucose. A clinical staff member will check the patient's blood sugar by performing a glucose finger stick with the Accuchek inform II meter.,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:99 Years",No,50
NCT04361643,Not yet recruiting,"October 27, 2020","December 31, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:60 Years,Max Age:N/A",No,120
NCT04568421,Recruiting,"August 18, 2020","December 31, 2021",Rheumatic Diseases,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,3000
NCT04322344,Recruiting,"March 23, 2020","December 30, 2020",Coronavirus Infections,"Non-Randomized,Parallel Assignment,Supportive Care,Double (Participant, Care Provider)","gender:All,Min Age:18 Years,Max Age:75 Years",No,120
NCT04365361,Recruiting,"April 26, 2020","March 31, 2021",Mental Health Wellness 1,"Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,300
NCT04252274,Recruiting,"January 30, 2020","December 31, 2020","Pneumonia, Pneumocystis,Coronavirus","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,30
NCT04363034,Available,N/A,N/A,N/A,N/A,"gender:All,Min Age:18 Years,Max Age:N/A",N/A,N/A
NCT04412668,Recruiting,"June 12, 2020","October 31, 2020",SARS-CoV-2 (COVID-19) Severe Pneumonia,"Randomized,Parallel Assignment,Patients will be randomized 1:1:1 to a single IV dose of ATYR1923 1 mg/kg, ATYR1923 3 mg/kg, or placebo.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),The Investigator, Sponsor, and patient will be blinded to treatment assignment; study center pharmacy personnel will be unblinded.","gender:All,Min Age:18 Years,Max Age:75 Years",No,30
NCT04396067,Not yet recruiting,October 2020,December 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,360
NCT04338958,Recruiting,"April 22, 2020","August 31, 2021",Covid-19,"N/A,Single Group Assignment,single arm, non-randomized,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04442204,Not yet recruiting,"June 22, 2020","July 13, 2020","Depression,Anxiety","Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,4000
NCT04401033,Completed,"May 11, 2020","June 30, 2020","SARS-CoV 2,COVID","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,450
NCT04572438,Recruiting,"August 1, 2020","August 1, 2021","Tracheostomy Complication,Covid19,Ventilator Lung","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2500
NCT04481685,Recruiting,"July 20, 2020",July 2022,Covid19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Care Provider)","gender:All,Min Age:18 Years,Max Age:N/A",No,36
NCT04337996,Recruiting,"July 13, 2020",December 2020,COVID-19,"N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,165
NCT04450017,Recruiting,"April 6, 2020",August 2020,SARS-CoV2,"Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:90 Years",No,150
NCT04357847,Recruiting,"April 9, 2020","August 31, 2020","Covid-19,Endothelial Dysfunction,Thrombosis,Critically Ill","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04444115,Not yet recruiting,"June 22, 2020","July 13, 2020",Loneliness During COVID-19,"Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,10084
NCT04367350,Recruiting,"March 20, 2020","March 31, 2022","COVID,Sars-CoV2,Corona Virus Infection,Myositis,Myocarditis","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04493268,Completed,"March 7, 2020","July 21, 2020","Hyponatremia,Covid19,Corona Virus Infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:1 Month,Max Age:100 Years",No,250
NCT04363372,Recruiting,June 2020,September 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,90
NCT04337424,Completed,"April 13, 2020","July 20, 2020",SARS-CoV-2,"Case-Control,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:90 Years",No,180
NCT04430608,Recruiting,"May 25, 2020","May 25, 2021","Diabetes,Covid-19,Infection","Randomized,Parallel Assignment,Patients are randomized 1:1 to either CGM or Fingerprick group,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,72
NCT04473118,Recruiting,"July 11, 2020",June 2021,COVID-19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,25000
NCT04367077,Recruiting,"April 28, 2020",August 2022,ARDS,"Randomized,Sequential Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:89 Years",No,400
NCT04393961,Recruiting,"April 5, 2020","August 29, 2020","COVID19,COVID-19,Coronavirus","Non-Randomized,Parallel Assignment,This study will include four arms. The experiences across all 4 arms will be exactly the same. Each arm has a slightly different experience with COVID-19.,Device Feasibility,None (Open Label),This is a device feasibility trial. There is no blinding or masking.","gender:All,Min Age:18 Years,Max Age:100 Years",No,600
NCT04425616,Recruiting,"May 29, 2020","November 30, 2022","Cancer,COVID","N/A,Single Group Assignment,Non-randomised phase III interventional trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,1100
NCT04368793,Recruiting,"April 6, 2020","December 31, 2021","COVID-2019 Pneumonia,Pulmonary Rehabilitation","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:20 Years,Max Age:85 Years",No,200
NCT04413968,Recruiting,"June 2, 2020","June 2, 2021","Coronavirus,Coronavirus Infection,Covid19,Sars-CoV2","N/A,Single Group Assignment,Cross-sectional, multi-center, non-randomized study,Diagnostic,None (Open Label)","gender:All,Min Age:1 Month,Max Age:N/A",No,600
NCT04523012,Recruiting,"July 1, 2020","June 30, 2022",Covid19,"Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2200
NCT04558203,Recruiting,"September 22, 2020","October 30, 2020",Covid19,"Cohort,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,450
NCT04435327,Recruiting,"August 17, 2020",April 2021,"COVID,Pneumonia, Viral,Barotrauma,Interstitial Lung Disease,Bronchiectasis Adult,Emphysema","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,300
NCT04401449,Recruiting,"May 20, 2020","May 1, 2024","Acute and Long Term Effects of COVID-19:on Systemic Inflammation,Acute and Long Term Effects of COVID-19 on Lung Function,Acute and Long Term Effects of COVID-19 on Mrain Function,Acute and Long Term Effects of COVID-19 on Cardiac Function,Acute and Long Term Effects of COVID-19 on Kidney Function","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,180
NCT04477954,Recruiting,"July 6, 2020","December 30, 2020",Covid19,"Randomized,Parallel Assignment,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04479137,Completed,"March 10, 2020","July 14, 2020","Covid-19,Risk Factor, Mortality","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:50 Years",No,5000
NCT04333849,Completed,"March 25, 2020","May 11, 2020",Coronavirus,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:70 Years,Max Age:N/A",No,132
NCT04335773,Recruiting,"April 3, 2020","December 31, 2030","Pediatric Respiratory Diseases,COVID,Fatigue Post Viral","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:18 Years",No,350
NCT04530461,Recruiting,"June 1, 2020","January 31, 2021","SARS-CoV Infection,Systemic Disease,Systemic Lupus Erythematosus,Sjogren's Syndrome,Sarcoidosis,Inflammatory Myopathy,Behçet Disease,Rheumatoid Arthritis,Spondyloarthritis","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04343404,Completed,"April 1, 2020","April 15, 2020",Respiratory Distress Syndrome,"Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04442789,Recruiting,"May 20, 2020","December 31, 2023","Lung Diseases,Cardiac Disease,Inflammatory Reaction","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04551755,Not yet recruiting,September 2020,December 2020,Covid19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,188
NCT04343794,Recruiting,"April 1, 2020","January 31, 2022",COVID19,"Randomized,Parallel Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04381351,Recruiting,"April 16, 2020","July 31, 2021",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:90 Years",No,50
NCT04499378,Not yet recruiting,"August 15, 2020","April 30, 2022","Covid19,Influenza A H1N1,Intubation Complication,Morality,Lung Injury, Acute","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,200
NCT04330586,Recruiting,"April 1, 2020","December 31, 2020",COVID-19,"Randomized,Parallel Assignment,This multicenter study is an open-labelled, randomized clinical trial for 1:1 ratio of ciclesonide or control arm (standard care),Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,94
NCT04420247,Recruiting,"April 16, 2020","August 31, 2020","COVID,COVID-19,SARS-CoV 2,Coronavirus,Corona Virus Infection","Randomized,Parallel Assignment,Two arms - Intervention and Control Intervention received unblinded treatment with Chloroquine or Hyroxycloroquine for 5 days, as well as standard treatment available and recomended by the Brazilian Guidelines for COVID-19.
Control group received just the standard treatment available and recomended by the Brazilian Guidelines for COVID-19.,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04343092,Completed,"April 18, 2020","June 1, 2020",COVID 19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04470414,Not yet recruiting,"August 1, 2020","September 1, 2021",Covid19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:20 Years,Max Age:N/A",No,100
NCT04505605,"Active, not recruiting","May 14, 2020","November 30, 2020","Community-acquired Pneumonia,Covid19","Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04452318,Recruiting,"July 13, 2020","August 15, 2021",Healthy Participants,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04347226,Recruiting,"April 16, 2020",September 2022,"Solid Tumor,Sars-CoV2,Hematological Malignancy","Randomized,Parallel Assignment,Participants will receive either BMS-986253 2400mg intravenous (IV) at 0 and 2 weeks (if patient is still hospitalized) and then 4 weeks (only if continued severe respiratory disease) or standard of care treatment.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,138
NCT04482361,Not yet recruiting,July 2020,October 2020,COVID-19,"Ecologic or Community,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,5400
NCT04382950,Not yet recruiting,July 2020,December 2020,COVID,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:60 Years",No,24
NCT04420988,Available,N/A,N/A,N/A,N/A,"gender:All,Min Age:18 Years,Max Age:N/A",N/A,N/A
NCT04568148,Recruiting,"April 15, 2020","December 31, 2021","Covid-19,SARS-CoV 2,Coronavirus,COVID","Other,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04352348,Recruiting,"March 31, 2020","March 31, 2022",COVID-19,"Non-Randomized,Parallel Assignment,Basic Science,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04412746,Recruiting,"April 1, 2020","June 30, 2020","Coronavirus Infections,Diabetes Mellitus,Prevalence,Risk Factors,Patient Outcome Assessment,Severe Acute Respiratory Syndrome","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:16 Years,Max Age:N/A",No,100
NCT04410471,Recruiting,"May 29, 2020","June 30, 2021","Liver Transplant Infection,Covid19,Mortality,Immune Response","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,300
NCT04518514,Recruiting,"April 20, 2020","November 30, 2020",Patients Undergoing Elective Surgery With Anesthesia,"N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04460196,Completed,"July 8, 2020","September 18, 2020",Emergency Medicine,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,900
NCT04368221,"Active, not recruiting","May 4, 2020",May 2021,Covid-19,"Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,576
NCT04401098,Recruiting,"May 2, 2020","April 1, 2021",COVID 19,"Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,700
NCT04382651,Recruiting,"June 11, 2020","January 26, 2021","COVID-19 Pneumonia, Impaired Respiratory Function","Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:80 Years",No,120
NCT04549922,Not yet recruiting,October 2020,December 2021,Covid19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),The placebo used in the present study will consist of 0.9% NaCl Solution, which has the same physical characteristics as the ISIS 721744 drug. The placebo solution will be prepared by the nurse or pharmacist of the research team at the time of application. The nurse will be trained on the procedures for adequate blinding of the intervention. The pharmacist at the site level will not be blind, but the rest of the ream (nurse, physicians, patients, etc) will be blinded.","gender:All,Min Age:18 Years,Max Age:80 Years",No,90
NCT04331886,Recruiting,"April 13, 2020",March 2021,"COVID-19,Coronavirus","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,5000
NCT04395885,Completed,"June 1, 2020","September 15, 2020",Sexual Dysfunction,"Other,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:40 Years",No,306
NCT04500600,Recruiting,"June 11, 2020","July 1, 2021","COVID-19 Infection,Hematopoietic and Lymphoid Cell Neoplasm,Malignant Solid Neoplasm","Case-Only,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50000
NCT04460534,Recruiting,"May 7, 2020","August 31, 2021",COVID,"N/A,Single Group Assignment,This is a prospective monocentric, open-label, prospective study of male patients with CoV-2-SARS.,Diagnostic,None (Open Label)","gender:Male,Min Age:18 Years,Max Age:65 Years",No,100
NCT04558372,Recruiting,"April 1, 2020",December 2020,COVID-19,"Non-Randomized,Single Group Assignment,3 groups:
COVID-19 patients
non COVID-19 patients
suspected COVID-19 patients,Diagnostic,Triple (Participant, Investigator, Outcomes Assessor),The person who operates breath test is blinded to the results of swab. The swab taker is blinded to the result of breath sample. The patients also do not know the results of the interpretation of the breath sample. Patients will receive information on the results of the oro/ nasopharyngeal swab in accordance with the COVID-19 health service standards. The final data processor is also blinded to the results of nose and throat swabs. The breath sampling data is saved in graphic form which interpretation will be carried out later by the data processor at the final stage.","gender:All,Min Age:4 Years,Max Age:N/A",No,1543
NCT04347824,Recruiting,"April 27, 2020","December 31, 2021",Covid-19,"Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04323332,Not yet recruiting,March 2020,April 2020,COVID-19,"Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:N/A,Max Age:85 Years",No,50
NCT04574219,Not yet recruiting,October 2020,December 2022,"Anxiety,Surgery","Randomized,Parallel Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:4 Years,Max Age:12 Years",No,184
NCT04304690,Recruiting,"March 16, 2020","October 16, 2020",Sars-CoV2,"N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,1000
NCT04325906,Recruiting,"April 2, 2020","December 31, 2020","Prone Positioning,High Flow Nasal Cannula,Acute Respiratory Distress Syndrome,Corona Virus Infection","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,346
NCT04323878,Recruiting,"June 1, 2020","November 9, 2020",Early CPAP Ventilation in COVID-19 Patients,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,3000
NCT04525079,Recruiting,"July 18, 2020","November 30, 2020",SARS-CoV-2 Infection,"Randomized,Sequential Assignment,Screening,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:19 Years,Max Age:55 Years",No,32
NCT04405986,Recruiting,"May 19, 2020","December 19, 2020",SARS-CoV 2,"N/A,Single Group Assignment,Health Services Research,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,38
NCT04472728,Recruiting,"June 16, 2020",September 2021,"Covid-19,SARS-CoV2","Randomized,Sequential Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:55 Years,Max Age:N/A",No,310
NCT04555122,Not yet recruiting,"September 29, 2020","July 28, 2022",Social Distance,"Randomized,Parallel Assignment,Other,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,52500
NCT04392427,Not yet recruiting,October 2020,May 2022,"COVID,Drug Effect","Randomized,Sequential Assignment,a sequential clinical trial in this design sample size is not fixed in advance. Instead data will be evaluated as they are collected, and further sampling is will be stopped in accordance with a pre-defined stopping rule as soon as significant results are observed. After ""n"" (10 subjects in each group) subjects in each group are available an interim analysis will be conducted. A statistical test will be performed to compare the two groups and if the null hypothesis is rejected the trial is terminated; otherwise, the trial continues, another n subjects per group will be recruited, and the statistical test is performed again, including all subjects. If the null is rejected, the trial is terminated, and otherwise it continues with periodic evaluations until a maximum number of interim analyses have been performed, at which point the last statistical test is conducted and the trial is discontinued,Treatment,Single (Outcomes Assessor),This search will focus on patients with COVID 19 infection this study is a prospective cohort study based on the analysis of response in comparative panel between two arm Nitazoxanide, Ribavirin and Ivermectin plus Zinc arm and other arm without any intervention as regards the safety and efficacy and cost effective result. Two years duration of the project would be enough to cover the stages of the work as shown below in the time plan. Initial stage of collecting materials and patients' clinical data, each patient will undergoes strict follow up period to reveal the clinical, laboratory and radiological response. The procedures are to be approved by the institutional ethical committee.","gender:All,Min Age:12 Years,Max Age:N/A",No,100
NCT04448418,"Active, not recruiting","May 20, 2020","November 20, 2020","Transgender Persons,Coronavirus,Coronavirus Infection,COVID,COVID-19","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,300
NCT04530422,Completed,"April 15, 2020","July 23, 2020",Covid19,"Randomized,Parallel Assignment,This randomized controlled clinical trial is a prospective, comparative, single blind, randomized study that was conducted on 250 patients, divided into two equal groups. The group I received Sofosbuvir plus Ledipasvir and Group II received Oseltamivir, hydroxychloroquine ""HCQ"" plus Azithromycin (the local medical committee of Almaza Fever Hospital guided standard treatment protocol for COVID-19),Treatment,Single (Participant),Randomization applied through computer-generated number and concealed using sequentially numbered, sealed opaque envelope to assign the patient to group 1 either group 2","gender:All,Min Age:18 Years,Max Age:75 Years",No,250
NCT04346368,Not yet recruiting,April 2020,December 2020,Coronavirus Disease 2019 (COVID-19),"Randomized,Parallel Assignment,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:75 Years",No,20
NCT04445961,Completed,"May 1, 2020","August 14, 2020",SARS Pneumonia,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:90 Years",No,117
NCT04517006,Not yet recruiting,August 2020,November 2020,"Happiness,Anxiety,Depression,Morality","Randomized,Factorial Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,1542
NCT04433078,Recruiting,"June 22, 2020",July 2021,"Cytokine Storm,SARS-CoV-2","Randomized,Parallel Assignment,This study will randomize 20 patients with confirmed or highly suspected early stage severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients to Doxycycline (100 mg BID) or Placebo.,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04469179,Recruiting,"August 20, 2020",December 2020,"COVID-19,SARS-CoV2","Randomized,Sequential Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:60 Years",No,21
NCT04363229,Not yet recruiting,July 2020,June 2021,Occupational Stress,"Other,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:22 Years,Max Age:N/A",No,250
NCT04416893,Not yet recruiting,"June 7, 2020","November 15, 2020",COVID19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:15 Years",No,630
NCT04333589,Recruiting,"April 1, 2020","September 15, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,210
NCT04382729,Recruiting,"April 17, 2020",July 2020,COVID-19 Pneumonia,"Randomized,Parallel Assignment,Supportive Care,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04334005,Not yet recruiting,"April 10, 2020","June 30, 2020",Patients Infected With COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Investigator, Outcomes Assessor)","gender:All,Min Age:40 Years,Max Age:70 Years",No,200
NCT04379492,Withdrawn,"May 5, 2020","September 25, 2020","COVID-19,COVID19,Sars-CoV2,SARS-Cov-2","Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04554251,Enrolling by invitation,"September 1, 2020","December 30, 2020","Covid19,Global Impact,Pulmonology","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04364737,Recruiting,"April 17, 2020","April 30, 2023","COVID-19,Coronavirus,Coronavirus Infection","Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04355234,Recruiting,"May 4, 2020","August 31, 2021",Pregnancy,"Non-Randomized,Parallel Assignment,Prospective, multicenter, open study with inclusions of 2200 parturients. All parturients divided into 2 groups:
2000 patients whose SARS-Cov-2 status is unknown during pregnancy
200 patients who presented a SARS-CoV-2 infection confirmed by PCR during pregnancy whatever the term,Screening,None (Open Label)","gender:Female,Min Age:18 Years,Max Age:N/A",No,2200
NCT04393324,Recruiting,"April 24, 2020","June 30, 2020","COVID-19,ARDS, Human","Cohort,Other","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,2500
NCT04475562,Completed,"April 6, 2020","July 1, 2020","SARS-CoV Infection,Covid19","N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,219
NCT04409197,Completed,"May 8, 2020","July 11, 2020","Comorbidities,Confinement,Obesity","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,4789
NCT04365530,Recruiting,"April 1, 2020","December 31, 2022",COVID,"Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,2000
NCT04564287,Enrolling by invitation,"October 12, 2020","December 1, 2022",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04371029,Recruiting,"April 28, 2020","December 28, 2020","ARDS,COVID-19","N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,25
NCT04360122,Not yet recruiting,"May 20, 2020","December 1, 2020",Coronavirus Disease (COVID-19),"Randomized,Parallel Assignment,Phase III, randomized, open labelled, clinical trial on one hundred adult healthy healthcare workers,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04422613,Recruiting,"May 28, 2020",May 2022,"Pneumonia, Viral","N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04384029,"Active, not recruiting","March 24, 2020","March 31, 2022","COVID,CVD","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,7000
NCT04531748,Not yet recruiting,September 2020,September 2021,Covid19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),The Medical Safety Officer will not be blinded.","gender:All,Min Age:18 Years,Max Age:N/A",No,390
NCT04410835,Recruiting,"April 28, 2020","April 28, 2021","Corona Virus Infection,Psychiatric Disorder,Psychological Distress","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04568005,Completed,"June 1, 2020","August 1, 2020",Lymphedema,"Other,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04467047,Not yet recruiting,"July 25, 2020","December 30, 2020","COVID-19,Sars-CoV2","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,10
NCT04331899,"Active, not recruiting","April 24, 2020",May 2021,COVID-19,"Randomized,Parallel Assignment,An open-label, single-blind randomized controlled trial. Study participants will be randomly assigned 1:1 to a single subcutaneous dose of Peginterferon Lambda-1a or placebo along with the standard of care.,Treatment,Single (Participant),Single-blind study in which only patients are blinded.","gender:All,Min Age:18 Years,Max Age:75 Years",No,120
NCT04489446,Recruiting,August 2020,March 2021,"Covid19,SARS-COV2 Infection","Randomized,Parallel Assignment,Eligible participants will be randomised to either sildenafil or placebo for up to seven days.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04459455,Recruiting,"August 19, 2020","September 15, 2020",Anxiety,"Randomized,Parallel Assignment,We will use a between-subjects design; participants will be randomized to receive either the active Contain COVID Anxiety SSI or the placebo Remain COVID Free SSI,Treatment,Triple (Participant, Investigator, Outcomes Assessor),This randomization of the order will occur using the randomizer within Qualtrics Survey Software, making the randomization process double-blind. To triple-blind our analysis process, the data will be downloaded from Qualtrics and the variable indicating what order the SSIs were presented in will be recoded before the primary analyses are conducted. Therefore, the primary analyses will be conducted without the knowledge of which condition is which.","gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04389554,Completed,"May 14, 2020","May 29, 2020","COVID-19,D-dimer","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:45 Years",No,300
NCT04482387,Not yet recruiting,"July 24, 2020","January 1, 2021","Visual Impairment,Amblyopia Suspect","Sequential Assignment,Patients will test their own vision twice using the DigiVis app twice, subsequently they will have visual acuity assessment in eye clinic by a trained examiner. The results of visual acuity will be compared using Bland Altman statistical analysis.,Diagnostic,None (Open Label),The eye clinic visual acuity examiner will be masked to the result of the DigiVis tests.","gender:All,Min Age:5 Years,Max Age:85 Years",No,250
NCT04364594,Completed,"March 26, 2020","May 30, 2020","COVID 19,Pulmonary Disease","N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04380792,Recruiting,"April 13, 2020","June 30, 2025",COVID-19,"Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,5000
NCT04535297,Completed,"May 10, 2020","June 30, 2020","Parkinson Disease,Stroke","Case-Only,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,198
NCT04399733,Not yet recruiting,"February 1, 2021","February 1, 2024","COVID-19, SARS-CoV 2 Infection,Health Disparities","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:6 Years,Max Age:N/A",No,12800
NCT04434417,Recruiting,"April 15, 2020","December 31, 2020",COVID,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04486729,Recruiting,"July 1, 2020","October 20, 2020","Covid19,ARDS, Human","Case-Crossover,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,15
NCT04298814,Withdrawn,"August 7, 2020","December 30, 2020","COVID-19,Endotracheal Intubation","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:90 Years",No,0
NCT04359810,Recruiting,"April 21, 2020",April 2021,SARS-CoV Infection,"Randomized,Parallel Assignment,A total of 105 eligible subjects will be randomized in a 2:1 ratio to receive either convalescent plasma qualitatively positive for SARS-CoV-2 antibody (anti-SARS-CoV-2 plasma) or non-convalescent fresh frozen plasma (control plasma).,Treatment,Double (Participant, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,105
NCT00571389,Recruiting,November 2007,February 2025,"Solid Tumor, Adult,Healthy Donors,COVID-19 Donors","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04400929,Recruiting,"June 2, 2020",June 2022,"COVID,Sars-CoV2,ARDS, Human","Randomized,Parallel Assignment,This is a randomized, double-blind, placebo-controlled clinical trial of iv Leukine® in 30 patients with confirmed COVID-19 and acute hypoxic respiratory failure.,Treatment,Double (Participant, Investigator),This is a double-blind study to investigate immediate versus delayed treatment of iv Leukine® in improving oxygenation and short- and long-term outcome of COVID-19 patients with acute hypoxic respiratory failure. The study will be unblinded at Day 5, or at any time within the first 5 days of study should the patient deteriorate clinically with need for supplemental oxygen FiO2 requirement ≥ 0.5.","gender:All,Min Age:21 Years,Max Age:80 Years",No,30
NCT04447222,Recruiting,"May 12, 2020","July 21, 2021","COVID-19 Infection,Malignant Solid Neoplasm","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1242
NCT04445415,Not yet recruiting,"July 1, 2020","September 1, 2021",COVID-19,"Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,250
NCT04312997,Recruiting,"June 16, 2020",December 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04528667,Not yet recruiting,September 2020,May 2021,Covid19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04400006,Completed,"May 6, 2020","May 17, 2020",Corona Virus Infection,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:90 Years",No,71
NCT04387929,Recruiting,"May 4, 2020","May 30, 2021",COVID-19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:90 Years",No,6000
NCT04421027,Recruiting,"June 12, 2020","December 5, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,600
NCT04442360,Not yet recruiting,"June 22, 2020","July 13, 2020","Depression,Generalized Anxiety,Health Anxiety","Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,4000
NCT04452643,Not yet recruiting,July 2020,December 2021,Covid19,"Randomized,Parallel Assignment,Double blind placebo control,Prevention,Triple (Participant, Care Provider, Investigator),Double blind placebo control","gender:All,Min Age:18 Years,Max Age:65 Years",No,3312
NCT04306497,Completed,"January 22, 2020","May 30, 2020",COVID-19,"Cohort,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,340
NCT04366856,Recruiting,"June 26, 2020",January 2021,"COVID,ARDS","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,500
NCT04476888,Recruiting,"April 26, 2020",September 2020,Covid19,"Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04473365,Recruiting,"July 20, 2020","June 30, 2021","SARS-CoV-2,COVID-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,186
NCT01306084,Recruiting,"March 5, 2011",N/A,N/A,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1000
NCT04420416,Recruiting,"April 1, 2020","July 30, 2020","Depression, Anxiety","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,720
NCT04399889,Recruiting,"June 18, 2020","July 31, 2021","COVID,Corona Virus Infection,COVID19","Randomized,Single Group Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04575584,Not yet recruiting,"October 19, 2020","October 18, 2021",Coronavirus Disease (COVID-19),"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,1300
NCT04319016,Recruiting,"January 1, 2020","May 1, 2020",Infection Viral,"Cohort,Other","sampling_method:Non-Probability Sample,gender:Female,Min Age:N/A,Max Age:N/A",No,200
NCT04346810,Not yet recruiting,"April 15, 2020","September 1, 2020","COVID-19,Burnout, Caregiver,Intensive Care Unit,Stress, Psychological","Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04533048,"Active, not recruiting","August 7, 2020",December 2020,Covid19,"Randomized,Sequential Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:45 Years",No,42
NCT04403646,Not yet recruiting,"June 1, 2020","October 31, 2020","COVID-19,SARS-CoV 2,Coronavirus Infection","Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,140
NCT04280705,Completed,"February 21, 2020","May 21, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:99 Years",No,1062
NCT04357444,Not yet recruiting,June 2020,August 2020,COVID 19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04408339,Recruiting,"April 15, 2020","April 14, 2022","Cancer,COVID","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04405492,Not yet recruiting,"May 25, 2020","March 25, 2021","SARS-CoV 2,COVID-19","Non-Randomized,Parallel Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,1210
NCT04510194,Not yet recruiting,September 2020,September 2021,"Covid19,SARS-CoV Infection","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:30 Years,Max Age:85 Years",No,1522
NCT04577105,Completed,"April 1, 2020","October 1, 2020","Covid19,ARDS,Pneumonia, Viral,Computed Tomography","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,233
NCT04376034,Recruiting,"April 16, 2020","March 30, 2021","COVID19,Coronavirus Infection,Coronavirus,Virus Diseases,RNA Virus Infections","Non-Randomized,Sequential Assignment,Prospective intervention,Treatment,None (Open Label)","gender:All,Min Age:31 Days,Max Age:N/A",No,240
NCT04390074,Completed,"May 27, 2020","June 4, 2020","COVID-19,Critical Illness","Case-Control,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,9905
NCT04466540,Recruiting,"May 12, 2020","December 30, 2020",COVID-19,"Randomized,Parallel Assignment,Pragmatic, double-blind, placebo-controlled randomized parallel-group, two-arm clinical trial (with allocation ratio 1:1),Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Randomization (1:1) is generated by a validated software and performed in permuted blocks of size 8. Concealment of the randomization list is maintained through a 24-hour, centralized, automated, internet-based randomization system. Furthermore, as placebo-controlled study, the placebo will have the same structural characteristics as the active drug and will be dispensed in cartridges that do not allow the identification of what is being given","gender:All,Min Age:18 Years,Max Age:N/A",No,1300
NCT04424901,Recruiting,"May 3, 2020","May 30, 2021","COVID-19 Pneumonia,Vascular Complications","Randomized,Single Group Assignment,Randomized Open Label Study Standard Care vs. Standard Care with Dipyridamole,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04427501,Recruiting,"June 17, 2020","January 15, 2021",COVID-19,"Randomized,Sequential Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,800
NCT04333732,Recruiting,"September 4, 2020",August 2021,COVID 19,"Randomized,Parallel Assignment,An international, multi-site, randomized, placebo-controlled, Bayesian platform clinical trial. Initially there will be 2 arms, but we anticipate adding intervention arms to the platform. Combining interventions, allowing assessment of potential interactions, will be considered when arms are added.,Prevention,Double (Participant, Investigator),For the MR or MMR vaccine, there will be a placebo vaccine. Attempts will be made to maintain masking for other interventions (e.g. oral tablets) added to the platform by including suitable placebo options.","gender:All,Min Age:18 Years,Max Age:N/A",No,30000
NCT04416256,Recruiting,"February 1, 2020",February 2022,COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,230000
NCT04379310,Completed,"May 1, 2020","May 8, 2020",Covid-19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:99 Years",No,54
NCT04298060,Not yet recruiting,July 2020,September 2022,"Influenza Infection,SAD-RV Infection and COVID-19","Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator),Stage 2, Ansun will know the dosage.","gender:All,Min Age:18 Years,Max Age:N/A",No,280
NCT04542694,Completed,"May 21, 2020","August 20, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,200
NCT04453891,Not yet recruiting,"July 15, 2020","December 15, 2020",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:55 Years,Max Age:N/A",No,16
NCT04381273,Recruiting,"May 8, 2020","July 31, 2020","Covid-19,Periodontal Diseases","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04446104,Completed,"May 13, 2020","August 31, 2020",Covid-19,"Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:Male,Min Age:21 Years,Max Age:60 Years",No,4257
NCT04376515,"Active, not recruiting","March 20, 2020","September 1, 2020",Anxiety,"Randomized,Parallel Assignment,Supportive Care,Single (Participant)","gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04368377,Completed,"April 6, 2020","April 23, 2020","Pneumonia, Viral,Corona Virus Infection,Respiratory Failure,Embolism and Thrombosis","N/A,Single Group Assignment,Compassionate-use, proof of concept, interventional, prospective,,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,5
NCT04361838,Recruiting,"June 1, 2020","August 31, 2020",Coronavirus Infection,"Randomized,Parallel Assignment,Supportive Care,Double (Participant, Care Provider)","gender:All,Min Age:18 Years,Max Age:110 Years",No,1000
NCT04396314,Not yet recruiting,"September 1, 2020","April 30, 2021",PostTraumatic Stress Disorder,"Randomized,Parallel Assignment,randomized controlled clinical trial,Treatment,Single (Outcomes Assessor),The researcher will be blinded to group of participant","gender:All,Min Age:18 Years,Max Age:N/A",No,54
NCT04556318,Recruiting,September 2020,March 2021,Covid19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04336215,Recruiting,"April 7, 2020","October 21, 2021","Coronavirus,SARS-CoV-2","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:20 Years,Max Age:N/A",No,750
NCT04357314,Completed,"March 1, 2020","May 31, 2020",Myocardial Infarction,"Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,6332
NCT04497779,Recruiting,"July 13, 2020","August 21, 2022","Asymptomatic COVID-19 Infection Laboratory-Confirmed,Symptomatic COVID-19 Infection Laboratory-Confirmed","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,800
NCT04374942,Enrolling by invitation,"April 30, 2020","January 30, 2022","Pre-Exposure Prophylaxis,Coronavirus,SARS-CoV 2","Randomized,Parallel Assignment,The HEROS study is a double-blind, randomized placebo controlled trial of oral HCQ 400 mg taken once daily for three months as PrEP to prevent COVID-19 in health care workers in the emergency department.,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),This trial is fully-blinded, at the level of the participant, study coordinator, and investigator. Study drug and placebo will be identical in appearance and will be provided by the manufacturer. They will be packaged in identical bottles and dispensed by the Research Clinical Trials Pharmacy at UHN.","gender:All,Min Age:18 Years,Max Age:N/A",No,988
NCT04383002,Recruiting,"September 2, 2020",December 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04334291,Recruiting,"March 23, 2020","May 5, 2020",COVID 19,"Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,6000
NCT04357535,Completed,"May 10, 2020","August 1, 2020",COVID-19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,314
NCT04362995,Recruiting,"April 23, 2020","March 20, 2025","COVID-19,Coronavirus Infection,Coronavirus,SARS-CoV-2","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1517
NCT04573634,Recruiting,"May 15, 2020","December 31, 2023","Covid19,SARS-CoV Infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,960
NCT04401202,Recruiting,"May 21, 2020","December 31, 2020","COVID-19,SARS-CoV-2","Randomized,Parallel Assignment,Prospective, randomized, open-label, controlled clinical study,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,200
NCT04398004,Recruiting,"May 6, 2020","May 6, 2022","COVID-19,Virus Diseases,Corona Virus Infection","N/A,Single Group Assignment,Treatment with clarithromycin,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,90
NCT04473300,Recruiting,"May 11, 2020","August 31, 2020","Critical Illness,ARDS","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04570462,Recruiting,"May 18, 2020","December 31, 2020",COVID19 ARDS,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:100 Years",No,20
NCT04358068,Completed,"May 1, 2020","July 7, 2020","COVID-19,SARS-CoV 2","Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04521036,Not yet recruiting,"December 1, 2020","October 30, 2021",COVID 19,"Randomized,Parallel Assignment,This trial is a randomized comparative trial. Patients will be randomized between the infusion of 500mL of Convalescent Plasma versus the standard of care,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,44
NCT04322565,Recruiting,"April 20, 2020","December 21, 2020","Coronavirus Infections,Pneumonia, Viral","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:100 Years",No,310
NCT04429815,Not yet recruiting,"July 1, 2020","April 1, 2021",Smoking Behaviors,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,489
NCT04316884,Recruiting,"March 12, 2020","December 31, 2021","COVID-19,Organ Dysfunction Syndrome Sepsis,Organ Dysfunction Syndrome, Multiple,Septic Shock,Acute Kidney Injury,Acute Respiratory Distress Syndrome","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04525378,Recruiting,"July 1, 2020","October 31, 2020","Covid19,ARDS, Human","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04511923,Not yet recruiting,September 2020,January 2022,"Covid19,ARDS, Human,Lung Injury, Acute,Ventilation Perfusion Mismatch","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04451577,Recruiting,"June 1, 2020","June 1, 2023",COVID,"Case-Control,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,5000
NCT04534803,Not yet recruiting,September 2020,"November 30, 2021",Covid19,"Randomized,Parallel Assignment,Participants will be randomized in a 1:1 allocation to receive intradermal administration of BCG vaccination or placebo.,Prevention,Triple (Participant, Investigator, Outcomes Assessor),Participants and investigators and designated staff whose responsibility will be to administer the BCG vaccine or placebo will be blinded.","gender:All,Min Age:70 Years,Max Age:N/A",No,2100
NCT04445311,Recruiting,"May 31, 2020","August 15, 2020",COVID,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,100
NCT04446169,Recruiting,"June 27, 2020","September 2, 2020","SARS-CoV 2,Sexual Function and Fertility Disorders,Urinary Function Disorders,Urine,Semen","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:Male,Min Age:18 Years,Max Age:80 Years",No,50
NCT04468412,"Active, not recruiting","July 14, 2020","September 30, 2021","COVID,Vascular; Damage","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:16 Years,Max Age:N/A",No,203
NCT04418544,Recruiting,June 2020,December 2020,COVID-19,"Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04316377,"Active, not recruiting","March 25, 2020","March 3, 2025",Corona Virus Infection,"Randomized,Parallel Assignment,Two-arm, open label, pragmatic randomized controlled trial.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,53
NCT04425044,Completed,"April 12, 2020","May 28, 2020",Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04482595,Not yet recruiting,September 2020,July 2022,Pulmonary Fibrosis,"Randomized,Parallel Assignment,Randomized, placebo-controlled,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,66
NCT04376944,Recruiting,"April 1, 2020","December 30, 2020","Caregivers,COVID-19","Case-Control,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04363008,Recruiting,"March 30, 2020","September 30, 2021",COVID 19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,150
NCT04372368,No longer available,N/A,N/A,N/A,N/A,"gender:All,Min Age:18 Years,Max Age:N/A",N/A,N/A
NCT04486417,Recruiting,"June 1, 2020","July 31, 2020","Obesity,Telemedicine,Bariatric Surgery","Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:65 Years",No,20
NCT04498377,Recruiting,"October 9, 2020","June 30, 2021",Covid19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Patients will be randomized in a 1:1 ratio in a double-blind manner to receive F-652 or placebo.
An independent statistician from Medpace will generate the randomization schedule. Patients meeting eligibility criteria will be randomized on Day 1 in a 1:1 ratio to F-652 or placebo, respectively. Patients will be assigned a randomization number and treatment assignment according to the randomization schedule. This randomization schedule will be maintained by the investigative site pharmacist until it is appropriate to break the blind. The Investigator, investigative site personnel (except site-designated pharmacist and dedicated assistant), study monitors, vendors, Sponsor, and Medpace will remain blinded to treatment assignment.","gender:All,Min Age:18 Years,Max Age:N/A",No,38
NCT04348513,Recruiting,"May 29, 2020","May 31, 2021","Pulmonary Infection,Covid-19","Randomized,Parallel Assignment,Phase II, parallel, prospective, randomized, double-blind, placebo controlled trial,Treatment,Triple (Participant, Care Provider, Investigator),Double-blind","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04494646,Recruiting,"September 8, 2020","February 28, 2021",Covid19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator),All patients, investigators, site personnel, laboratories, and study personnel with direct involvement in the conduct of the study or their designees will be blinded to treatment assignments. To prevent potential bias, appropriate measures will be taken to ensure the blind is maintained for the patients and personnel mentioned previously. To maintain the blind, investigators will distribute blinded study drug treatment to patients as directed by the IWRS system. Investigators and patients will not be blinded to dose level, but will be blinded to treatment assignment (i.e., bardoxolone methyl vs. placebo).","gender:All,Min Age:18 Years,Max Age:N/A",No,440
NCT04575597,Not yet recruiting,"October 19, 2020","October 14, 2021",Coronavirus Disease (COVID-19),"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,1450
NCT04359121,Recruiting,"April 15, 2020","April 15, 2024",COVID19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:90 Years",No,600
NCT04542421,Recruiting,"July 1, 2020","December 1, 2021",Covid19,"N/A,Single Group Assignment,Health Services Research,None (Open Label)","gender:All,Min Age:18 Years,Max Age:100 Years",No,90
NCT04516824,Completed,"March 19, 2020","August 15, 2020",Orthopaedic Disorders,"Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:70 Years",No,2160
NCT04525911,Recruiting,"August 26, 2020",October 2022,Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,258
NCT04421508,Recruiting,"July 12, 2020",June 2021,"COVID-19,Coronavirus,Coronavirus Infection","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04333693,Not yet recruiting,"April 1, 2020","November 1, 2020","Vascular Surgical Procedures,COVID-19,Postoperative Complications","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04397380,Not yet recruiting,"May 20, 2020","July 1, 2020","Pyrexia,COVID","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:16 Years,Max Age:N/A",No,100
NCT04355715,"Active, not recruiting","April 1, 2019","October 20, 2020","COVID 19,SARS-Cov-2","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:99 Years",No,200
NCT04469153,Recruiting,"June 29, 2020","December 31, 2020","the Prognostic Value of Ferritin,Glycosylated Ferritin in SARS-CoV-2 Infection in Hospitalized COVID-19 Patients","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,57
NCT04420338,Recruiting,"June 5, 2020","December 15, 2020","Chronic Hemodialysis Patients,Caregivers of Chronic Hemodialysis Patients","Non-Randomized,Parallel Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,800
NCT04381000,Completed,"April 1, 2020","June 10, 2020",Chronic Pain,"Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,170
NCT04335747,Recruiting,"April 23, 2020","September 1, 2021","Rheumatoid Arthritis,Psoriatic Arthritis,Axial Spondyloarthritis,Systemic Lupus Erythematosus,Giant Cell Arteritis","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,333
NCT04412343,Recruiting,"May 23, 2020","October 5, 2020","Well-Being (Psychological Flourishing),Depression,Quality of Life,Loneliness,Physical Activity,Social Identification,Physical Health","Randomized,Parallel Assignment,Prevention,Single (Outcomes Assessor),No experimenter or investigator expectancy effects as all assessment occurs online (i.e., online questionnaire). Personnel who analyze the data collected from the study are not aware of the treatment applied to any given group.","gender:All,Min Age:65 Years,Max Age:N/A",No,600
NCT04348461,Not yet recruiting,"April 6, 2020","September 30, 2020","COVID,Respiratory Distress Syndrome","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04332042,Not yet recruiting,"April 10, 2020","July 10, 2020",SARS-COv2 Related Interstitial Pneumonia,"N/A,Single Group Assignment,prospective cohort study,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:65 Years",No,50
NCT04376853,Recruiting,"April 15, 2020",July 2020,COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04474483,Not yet recruiting,"August 11, 2020","August 10, 2021",COVID-19,"Randomized,Parallel Assignment,placebo-controlled randomized double-blind pilot trial,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04363203,Suspended,"April 30, 2020",August 2021,"SARS-CoV-2,COVID-19","Randomized,Single Group Assignment,A 3-arm RCT to determine the efficacy of hydroxychloroquine or azithromycin compared to placebo in treating mild to moderate COVID-19 among Veterans in the outpatient setting.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Eligible, consented patients will be randomized to a 1:1:1 treatment allocation, stratifying by age (<65, 65 or more) and region, and using randomly permutated blocks (block size of 3) within study site. Pharmacy is unblinded to study drugs.","gender:All,Min Age:216 Months,Max Age:N/A",N/A,300
NCT04441502,Recruiting,"March 30, 2020","December 31, 2020","Covid19,Interstitial Pneumonia","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,240
NCT04519125,Not yet recruiting,"August 30, 2020","April 1, 2021","Severe Acute Respiratory Syndrome Coronavirus 2,COVID-19","Randomized,Parallel Assignment,Randomized triple masked multicentric controlled trial to evaluate the effectiveness and safety of Tenofovir/Emtricitabine in addition to personal protective equipment in comparison to the use of personal protective equipment alone for the prevention of infection with severe acute respiratory syndrome coronavirus 2 / COVID-19 in health care personnel in Colombia.,Prevention,Triple (Participant, Care Provider, Investigator),Participant will not be informed that is either receiving or not the product of intervention, additionally, placebo will have a similar taste of the product of intervention and packaging will be the same for both.
Investigators will be masked because there is a central randomization and only the pharmacist of the study will now in which arm is assigned the participant Data analysis will be performed with an encrypted dataset which doesn't reveal which one is the intervention or which one is placebo","gender:All,Min Age:18 Years,Max Age:70 Years",No,950
NCT04307459,Recruiting,"March 19, 2020","December 31, 2020","Coronavirus Infections,Respiratory Failure,Ventilator Lung","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04372693,Enrolling by invitation,"September 1, 2020","February 28, 2021","Distance Learning-Online Learning,Traditional Classroom-Based Learning,Coronavirus Disease Social Distancing Measures,Nursing Students' Perception and Achievement","Non-Randomized,Parallel Assignment,Online Distance Learning with certain principals will be implemented for the study group and control group who learned by Traditional Classroom-Based will be selected retrospectively as baseline data, students' perception and achievement will be measured for both.,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,180
NCT04570982,Recruiting,"July 30, 2020","December 30, 2020",COVID-19,"Case-Crossover,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04444310,"Active, not recruiting","June 15, 2020","September 30, 2020",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,100
NCT04360954,Completed,"April 23, 2020","July 8, 2020","COVID,Coronavirus","Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,461
NCT04446377,Recruiting,"July 15, 2020","January 31, 2021",COVID-19 Disease,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double-blinded","gender:All,Min Age:18 Years,Max Age:N/A",No,142
NCT04410536,Not yet recruiting,June 2020,July 2022,"Migraine, Hemicrania","N/A,Single Group Assignment,withdrawal program will be performed at home,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:65 Years",No,25
NCT04402970,Recruiting,"June 19, 2020","May 31, 2022","SARS-CoV 2,ARDS","Non-Randomized,Single Group Assignment,Nebulized dornase alfa will be administered through the ventilator circuit at a dose of 2.5 mg, 12 hours apart, for 3 consecutive days. Patients will also receive lung protective ventilation (VC 6-8 ml/kg predicted body weight), plateau pressure < 30 cmH2O, targeted driving pressure < 15, neuromuscular blockade if indicated, and prone positioning based upon PaO2/FiO2 ratio < 150 or upon treating physician decision; along with all other ICU care based upon best practice standards and evidence based medicine.,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04377568,Not yet recruiting,"September 30, 2020","May 1, 2022","Hospitalized Children,Covid-19 Infection","Randomized,Parallel Assignment,Subjects will be randomized to receive either standard of care (SoC) products (control) or COVID-19 convalescent plasma (C19-CP) plus standard of care while being hospitalized for COVID-19 (ratio 1:2). The intervention will consist of a single transfusion of convalescent plasma.,Treatment,None (Open Label)","gender:All,Min Age:N/A,Max Age:18 Years",No,100
NCT04348422,Not yet recruiting,"April 20, 2020","December 31, 2020",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04420182,Recruiting,"August 17, 2020","December 31, 2021",Covid-19,"N/A,Single Group Assignment,Prospective non-randomized cohort study,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04305106,Recruiting,"March 17, 2020","July 31, 2020",COVID-19 Pneumonia,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:80 Years",No,140
NCT04506229,Recruiting,"August 20, 2020",September 2021,Covid19,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04392388,Recruiting,"May 1, 2020","December 31, 2020",SARS-CoV 2,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,110000
NCT04466605,Completed,"March 30, 2020","July 6, 2020",Chronic Musculoskeletal Pain,"Randomized,Parallel Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:60 Years",No,64
NCT04444713,Not yet recruiting,"June 22, 2020","July 13, 2020","Depressive Symptoms,Metacognitive Variables","Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,10084
NCT04435184,Recruiting,"July 9, 2020","October 1, 2020",COVID-19,"Randomized,Parallel Assignment,Double-blind, placebo-controlled, randomized interventional trial.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04439084,Enrolling by invitation,"March 6, 2020",June 2021,"COVID-19,Chronic Liver Disease","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04374786,Enrolling by invitation,"May 15, 2020","October 1, 2020","Perceived Stress,Anxiety,Sleep Disturbance,Burnout,PTSD","N/A,Single Group Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:99 Years",No,328
NCT04528771,Not yet recruiting,"October 31, 2020","April 30, 2021","SARS-CoV2 Infection,Covid19","Randomized,Parallel Assignment,Single-site double-blinded randomized placebo controlled trial with a non-inferiority design. The study will randomize 21 patients 2:1 to either S-nitrosylation therapy or placebo arms.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),The investigational product will be prepared and dispensed by designated unblinded site personnel at the pharmacy; the investigational product label will indicate the study number but will not indicate the treatment assignment. Any site personnel involved in the administration and assessment of the investigational product will be blinded to subject treatment assignments throughout the study.","gender:All,Min Age:18 Years,Max Age:89 Years",No,21
NCT04468256,Recruiting,"July 26, 2020",July 2022,"COVID-19,Cardiomyopathies","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04418193,Recruiting,"April 6, 2020","September 1, 2020",Coronavirus,"Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:99 Years",No,100
NCT04356885,Recruiting,"April 1, 2020","August 1, 2020",Mental Disorder,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:65 Years",No,600
NCT04407208,Completed,"May 1, 2020","June 22, 2020","Convalescence,Corona Virus Infection,Plaque","N/A,Single Group Assignment,single-arm, pre, and post-test dependent group,Health Services Research,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,10
NCT04500366,Not yet recruiting,September 2020,May 2021,Frailty,"Randomized,Parallel Assignment,Participants will be randomized into two arms (35/arm based on sample size calculation) for 12-weeks of socialization only or multi-modal frailty rehabilitation. The socialization only arm will receive 1x/week phone calls from medical student volunteers via the McMaster Student-Senior Isolation Prevention Partnership (SSIPP). Multi-modal frailty rehabilitation will involve virtual care including 1x/week socialization (SSIPP), 2x/week exercise (small group physiotherapy live-streamed sessions), nutrition (virtual dietician consult), and medication support (virtual pharmacist consult) all via a videoconferencing service.,Prevention,Double (Investigator, Outcomes Assessor),Outcome assessors, the study biostatistician, the investigative team, and the steering committee will be blinded to intervention assignments. Research assistants, study intervention personnel (pharmacist, instructors) and participants will not be blinded.","gender:All,Min Age:65 Years,Max Age:N/A",No,70
NCT04402060,Recruiting,"May 26, 2020",November 2020,"COVID,Covid-19,Coronavirus,Coronavirus Infection,Severe Acute Respiratory Syndrome,Severe Acute Respiratory Syndrome Coronavirus 2,Sars-CoV2,Ards,Acute Respiratory Distress Syndrome","Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,66
NCT04509999,Not yet recruiting,September 2020,September 2022,COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:Male,Min Age:18 Years,Max Age:99 Years",No,100
NCT04365959,"Active, not recruiting","March 20, 2020","May 31, 2020",Sars-CoV2,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:75 Years",No,56
NCT04414241,Not yet recruiting,June 2020,October 2020,SARS-CoV-2,"Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,320
NCT04353271,Terminated,"April 17, 2020","July 8, 2020","Covid 19,Corona Virus Infection","Randomized,Parallel Assignment,Randomized placebo verses medication clinical trial,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Blinded to subject and investigators","gender:All,Min Age:19 Years,Max Age:85 Years",No,58
NCT04279795,Recruiting,"January 20, 2020","February 28, 2021",Coronavirus,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,20
NCT04342195,Recruiting,"March 25, 2020",March 2021,"COVID-19,Coronavirus Infection,Corona Virus Infection","Case-Only,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:65 Years",No,50
NCT04565379,Recruiting,"September 25, 2020","November 30, 2020",COVID19 Pneumonia,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:79 Years",No,60
NCT04502108,Recruiting,"April 1, 2020","December 31, 2022","Exercise,Nutritional Status,Sleep","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:65 Years",No,1000
NCT04365348,Recruiting,"April 27, 2020","June 30, 2021",Mental Health Wellness 1,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,300
NCT04558307,Enrolling by invitation,"June 3, 2020","December 1, 2021",Coronavirus Disease (COVID-19),"Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1000
NCT04387786,"Active, not recruiting","March 31, 2020",July 2020,"COVID-19,Mechanical Ventilation","Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:85 Years",No,5
NCT04448743,Not yet recruiting,June 2020,November 2021,COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,175
NCT04432870,Enrolling by invitation,"June 9, 2020","April 30, 2021",Colon Cancer,"Other,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:45 Years,Max Age:75 Years",No,200
NCT04354259,Recruiting,"May 13, 2020","November 30, 2020","Sars-CoV2,Covid-19","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,140
NCT04382495,"Active, not recruiting","June 15, 2020","October 31, 2020",Cancer,"Other,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04364009,Recruiting,"April 27, 2020","September 24, 2021","COVID-19 Infection,ANAKINRA Treatment,Optimized Standard of Care (oSOC)","Randomized,Parallel Assignment,ANACONDA study is a French multicentre, open-label, randomized, controlled superiority trial comparing the administration of optimized standard of care and Anakinra versus optimized standard of care alone in patients hospitalized in a medical unit with COVID-19.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,240
NCT04324528,Recruiting,"March 27, 2020","November 26, 2020","Coronavirus,COVID-19,SARS-CoV Infection,Respiratory Failure,Cytokine Storm","Randomized,Single Group Assignment,randomized controlled trial examining COVID-patients requiring vv-ECMO therapy (+/- cytokine adsorption),Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:100 Years",No,30
NCT04429620,Recruiting,"May 30, 2020","December 31, 2020",Sars-CoV2,"Case-Control,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04540926,Not yet recruiting,September 2020,"September 30, 2020",COVID 19 Pneumonia,"Sequential Assignment,Consecutive patients with suspected or confirmed diagnosis of COVID-19 were assigned, in an unblinded and non-randomized fashion, to receive either steroids plus CsA (intervention group) or steroids only (standard of treatment in this hospital, control group), as per individual clinical judgment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04371848,"Active, not recruiting","April 16, 2020","May 7, 2020",Eating Habits,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2465
NCT04578509,Not yet recruiting,October 2020,June 2021,"SARS-CoV-2 Infection,COVID-19","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,2750
NCT04345601,Not yet recruiting,August 2020,May 2022,"Sars-CoV2,Acute Respiratory Distress Syndrome,COVID-19","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04369690,Recruiting,"April 3, 2020","April 3, 2021","COVID-19,Chronic Disease,Psychiatric Disorder,Cardiovascular Diseases","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:12 Years,Max Age:N/A",No,1000
NCT04492475,Recruiting,"August 4, 2020","November 1, 2023",COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:99 Years",No,1038
NCT03348670,"Active, not recruiting","July 20, 2020","November 28, 2020",Covid19,"N/A,Single Group Assignment,Treatment,None (Open Label),Open Label","gender:All,Min Age:22 Years,Max Age:72 Years",No,20
NCT04306393,Recruiting,"March 21, 2020","March 21, 2022","SARS (Severe Acute Respiratory Syndrome),Coronavirus","Randomized,Parallel Assignment,Treatment,Single (Participant),The patient is blinded to the treatment.","gender:All,Min Age:18 Years,Max Age:99 Years",No,200
NCT04412057,Recruiting,"June 9, 2020",November 2020,"COVID-19 Pneumonia,Acute Lung Injury,ARDS","Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator),Double-blind (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,82
NCT04481633,Not yet recruiting,September 2020,September 2020,COVID-19,"Non-Randomized,Parallel Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,800
NCT04384445,Recruiting,"September 8, 2020","December 31, 2020","Corona Virus Infection,COVID-19,SARS,Acute Respiratory Distress Syndrome","Randomized,Parallel Assignment,The trial has two groups, each with 10 subjects (n=20). All eligible study subjects will be randomized, double blinded, to either the treatment group or placebo group.,Treatment,Double (Participant, Investigator),Double blind: neither subjects nor the investigators who are assessing the patient are award of the treatment assignment until the end of the study.","gender:All,Min Age:18 Years,Max Age:N/A",N/A,20
NCT04345614,Recruiting,"April 8, 2020",April 2021,Pneumonia,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Matching placebo","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04383535,Completed,"May 15, 2020","September 27, 2020","SARS Virus,SARS-CoV-2,COVID-19","Randomized,Parallel Assignment,Multicenter randomized (2:1, 222 plasma 111 placebo), double-blind, placebo-controlled clinical trial,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),The pharmacist will be unblinded. The study intervention will be covered with an opaque development in order to ensure blinding of the intervention arm.","gender:All,Min Age:18 Years,Max Age:N/A",No,333
NCT04487691,Not yet recruiting,"August 3, 2020","December 30, 2021",Covid19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Care Provider)","gender:All,Min Age:18 Years,Max Age:85 Years",No,40
NCT04561180,Not yet recruiting,December 2020,December 2021,Pneumonia as One of the Lung Complications Caused by SARS-CoV-2 Infection,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:65 Years",No,96
NCT04532931,Recruiting,"September 3, 2020",January 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:65 Years",No,250
NCT04407663,Completed,"March 3, 2020","May 4, 2020","Bariatric Surgery Candidate,Patient Underwent Bariatric Surgery","Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,138
NCT04564040,Not yet recruiting,"October 7, 2020","November 30, 2020","Mantle Cell Lymphoma,COVID-19","Randomized,Crossover Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:55 Years",N/A,40
NCT04460105,Recruiting,"October 31, 2020","January 27, 2021",COVID-19 Pneumonia,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,24
NCT04332380,Completed,"May 1, 2020","July 28, 2020","Coronavirus,Coronavirus Infection","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:60 Years",No,10
NCT04380714,"Active, not recruiting","May 1, 2020","August 1, 2020","People Incarcerated,COVID-19","Ecologic or Community,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,700
NCT04316299,Completed,"February 26, 2020","March 8, 2020","COVID-19,Acute Kidney Injury,Kidney Function","Case-Control,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,287
NCT04061382,Recruiting,"October 15, 2019","June 30, 2021","Serogroup C Meningococcal Meningitis,Diphtheria,COVID-19","Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:24 Years",No,3500
NCT04341935,Not yet recruiting,"January 30, 2021","December 30, 2021","Coronavirus Infection,Type 2 Diabetes","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04345991,Recruiting,"April 15, 2020","June 1, 2020",Covid19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04471051,Recruiting,"April 30, 2020",April 2021,Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04339634,"Active, not recruiting","April 7, 2020","April 6, 2021","COVID,Drug Effect,Drug Interaction,Adverse Drug Event","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:55 Years,Max Age:N/A",No,12123
NCT04442048,Recruiting,"June 25, 2020","March 31, 2021","Cancer,Covid-19","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,1500
NCT04444687,Not yet recruiting,August 2020,February 2021,COVID,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04517695,Recruiting,"August 1, 2020","February 1, 2021","Covid19,Acute Respiratory Distress Syndrome","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:95 Years",No,30
NCT04326790,Recruiting,"April 3, 2020","September 30, 2020",Corona Virus Disease 19 (Covid 19),"Randomized,Parallel Assignment,Patient-level randomization scheme,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,180
NCT04459637,Not yet recruiting,"July 1, 2020","March 10, 2021",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:75 Years",No,200
NCT04405544,Recruiting,"May 22, 2020","October 22, 2020","Encephalopathy,COVID","Non-Randomized,Parallel Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:60 Years",No,60
NCT04517162,Recruiting,"August 19, 2020","June 19, 2021","Covid19,Cytokine Storm,Regulation of Inflammatory Response,Pulmonary Fibrosis","Randomized,Parallel Assignment,Double Blind Placebo-controlled Clinical Trial,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:80 Years",No,90
NCT04569019,Recruiting,"September 1, 2020","July 1, 2022",Vaccnation in HCW,"Case-Crossover,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04337008,Recruiting,"April 3, 2020","July 31, 2020",COVID 19,"Non-Randomized,Parallel Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04452812,Not yet recruiting,"July 6, 2020","April 1, 2021","COVID-19 Pneumonia,Convalescent Plasma","Randomized,Parallel Assignment,Pilot, experimental, randomized, prospective, longitudinal, clinical study,Treatment,Double (Participant, Care Provider)","gender:All,Min Age:18 Years,Max Age:N/A",No,15
NCT04451993,Recruiting,"June 25, 2020","December 31, 2020",Obstructive Sleep Apnea-hypopnea Syndrome,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:19 Years,Max Age:70 Years",No,60
NCT04549831,Recruiting,"April 8, 2020","April 8, 2026",COVID-19,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04534400,Recruiting,"September 1, 2020","January 15, 2021","SARS-CoV-2 Infection,Respiratory Failure With Hypoxia","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04394416,Recruiting,"June 2, 2020","June 1, 2023",COVID-19,"Randomized,Parallel Assignment,Arm A: Imatinib
Arm B: Placebo,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,204
NCT04445454,Recruiting,"June 12, 2020","September 30, 2022",Coronavirus Infection,"N/A,Single Group Assignment,This study is a monocentric prospective phase I/II clinical trial, aiming at evaluating the safety and efficacy of 3 intravenous administrations of BM-MSC in 20 patients with severe to critical COVID-19 pneumonia.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,20
NCT04344587,Enrolling by invitation,"April 23, 2020",December 2020,COVID-19,"Randomized,Parallel Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,560
NCT04429854,Recruiting,"May 2, 2020","November 2, 2021",COVID-19,"Randomized,Parallel Assignment,483 patients with 2:1 randomization. 322 patients receiving Convalescent Plasma - 161 patients receiving Standard of Care,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,483
NCT04371692,Not yet recruiting,April 2020,September 2020,Sars-CoV2,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04461925,Recruiting,"May 2, 2020",December 2021,COVID-19 Pneumonia,"Non-Randomized,Parallel Assignment,Experimental: stem cells therapy + treatment in according with approved by Ukrainian Health Ministry COVID-19 clinical protocol Experimental Group 1: Subjects with severe COVID-19 pneumonia shall be received three infusions of cryopreserved allogeneic P-MMSCs (1 million cells/kg body weight) at 2-days intervals: Day ""1"", Day ""4"", Day ""7"".
Control Group: treatment in according with approved by Ukrainian MoH COVID-19 clinical protocol.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,30
NCT04426344,Not yet recruiting,October 2020,December 2020,COVID 19,"Randomized,Parallel Assignment,Randomized, single center pilot study,Treatment,Single (Participant),Due to the nature of this study, the physicians will not be blinded to the randomization assignment, however participants will be blinded. Once a subject is randomized, the research team will receive the randomization assignment (core warming or standard of care) and proceed with the procedures per the assignment.","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04386447,Not yet recruiting,"September 1, 2020","December 31, 2020","Covid-19,Corona Virus Infection,SARS-CoV 2","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,145
NCT04356495,Recruiting,"July 29, 2020","January 28, 2021","Corona Virus Infection,Sars-CoV2","Randomized,Parallel Assignment,Phase III multi-centre, open-label, randomized controlled superiority multi-arm multi-stage, (MAMS) trial,Treatment,None (Open Label)","gender:All,Min Age:60 Years,Max Age:N/A",No,338
NCT04524715,Recruiting,"July 26, 2020","January 31, 2021",Covid19,"Randomized,Parallel Assignment,Blinded before and after comparison of COVID-19 patients treated with a red-light LLLT therapy in addition to standard treatment measures compared to a control group receiving only standard treatment measures.,Treatment,Single (Participant),All participants undergo LLLT treatment; however, the active group receives LED light in the red and IR range while the placebo group is told they are receiving IR light not visible to naked eye. All participants continue receiving standard treatments for COVID19 symptoms.","gender:All,Min Age:18 Years,Max Age:N/A",No,64
NCT04332016,Recruiting,"April 2, 2020",March 2023,Infection Viral,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:100 Years",No,2000
NCT04559074,Not yet recruiting,"September 30, 2020","July 31, 2021",Hypertension,"Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04502472,Recruiting,"June 6, 2020","December 31, 2021",Covid-19,"N/A,Single Group Assignment,Phase 1 will be recruitment and enrollment of plasma donors. Phase 2 will be continued recruitment and enrollment of plasma donors, with the addition of recruitment and enrollment of plasma recipients.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04353323,Not yet recruiting,"May 25, 2020","December 25, 2020","Infection, COVID-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,130
NCT04360486,Available,N/A,N/A,N/A,N/A,"gender:All,Min Age:N/A,Max Age:N/A",N/A,N/A
NCT04537351,Recruiting,"August 24, 2020","March 31, 2021","Covid19,Acute Respiratory Distress Syndrome","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,24
NCT04328129,Recruiting,"March 23, 2020","March 23, 2022","Coronavirus Infections,Severe Acute Respiratory Syndrome,SARS-CoV Infection","Non-Randomized,Parallel Assignment,Screening,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,1300
NCT04367883,Recruiting,"March 1, 2020","August 31, 2023","COVID19,Influenza Vaccination,ACE Inhibitors,ARB","Other,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,2574
NCT04452617,Completed,"March 19, 2020","July 1, 2020",COVID-19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04366947,"Active, not recruiting","April 14, 2020","May 20, 2020","Emergency Medicine,Cardiopulmonary Arrest,Shock","Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04413435,Recruiting,"October 30, 2020","December 25, 2020","Coronavirus Infection,Critical Illness,Characteristics Disease","Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,105
NCT04415879,Completed,"June 1, 2020","August 1, 2020",COVID-19,"Randomized,Crossover Assignment,Health Services Research,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04524234,Recruiting,"April 20, 2020","September 30, 2020","Covid19,Left Ventricular Dysfunction,Right Ventricular Dysfunction,Pulmonary Hypertension","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:99 Years",No,100
NCT04486001,Not yet recruiting,"August 15, 2020","January 15, 2021",Covid19,"N/A,Single Group Assignment,single group comparison with cohort of contemporaneous non-treated patients.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",N/A,20
NCT04346420,Completed,"April 9, 2020","May 1, 2020","COVID,Hypoxemia","Non-Randomized,Crossover Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,12
NCT04510467,Not yet recruiting,September 2020,February 2021,"Covid19,Systemic Autoimmune Disease,Inflammatory Rheumatism,Auto Inflammatory Diseases","Case-Control,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1313
NCT04336774,Withdrawn,July 2020,"November 9, 2020",COVID-19,"N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04542031,Not yet recruiting,October 2020,October 2021,"Covid19,Rheumatic Diseases","N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,7911
NCT04377724,"Active, not recruiting","April 27, 2020","June 30, 2021","Covid-19,Virus Disease","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:64 Years",No,3000
NCT04506632,Recruiting,"June 2, 2020","April 26, 2022","COVID-19,Mental Health Burden","Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04476602,Recruiting,"April 27, 2020","December 31, 2020",Covid-19 (SARS-CoV-2),"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04530578,Recruiting,"June 1, 2020","June 1, 2021","Covid19,Pneumonia","Randomized,Parallel Assignment,Controled, prospective, randomized, comparative against standard treatment.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:100 Years",No,200
NCT04522076,"Active, not recruiting","April 6, 2020","May 1, 2022",COVID 19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1124
NCT04401085,Completed,"April 23, 2020","May 1, 2020","COVID,SARS-CoV 2","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:8 Years,Max Age:89 Years",No,27000
NCT04497610,Not yet recruiting,"August 4, 2020","August 15, 2020",COVID19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:7 Years,Max Age:N/A",No,1000
NCT04510454,Not yet recruiting,September 2020,March 2021,"Cancer,COVID","N/A,Single Group Assignment,Nasopharyngeal and oropharyngeal samples will be analyzed by the standard RT-qPCR test and the ddPCR assay.,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04326387,Recruiting,"April 6, 2020","October 7, 2021","Acute Disease,Coronavirus,Respiratory Viral Infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:16 Years,Max Age:N/A",No,200
NCT04333862,Recruiting,"March 19, 2020","January 31, 2022",SARS-CoV-2,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04572412,Not yet recruiting,October 2020,April 2021,Covid19,"N/A,Single Group Assignment,Health Services Research,None (Open Label)","gender:All,Min Age:50 Years,Max Age:N/A",No,13
NCT04544605,Recruiting,"September 7, 2020","December 31, 2021",Post COVID-19,"Case-Only,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,150
NCT04527133,"Active, not recruiting","June 11, 2020","August 31, 2020",COVID-19,"Non-Randomized,Sequential Assignment,A non-comparative study of the efficacy and safety,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04466371,Not yet recruiting,"October 15, 2020","November 1, 2021",Covid19,"Case-Only,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,9209
NCT04542044,Completed,"April 2, 2020","June 30, 2020","Covid19,Pneumonia","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:99 Years",No,40
NCT04386109,Recruiting,"April 1, 2020","September 30, 2021",Neonatal COVID-19 Disease,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:29 Days",No,500
NCT04351399,Completed,"April 27, 2020","May 4, 2020","Sars-CoV2,Rheumatic Diseases,Rheumatoid Arthritis,Chronic Pain","Family-Based,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,318
NCT04359654,Not yet recruiting,"May 1, 2020","November 1, 2020","COVID19,Hypoxia","Randomized,Parallel Assignment,An open-label, randomised, Best-Available-Care (BAC) and historic-controlled trial of nebulised dornase alfa [2.5 mg BID] for 7 days in participants with COVID-19 who are admitted to hospital and are at risk of ventilatory failure,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:100 Years",No,50
NCT04425707,Recruiting,"June 9, 2020","September 1, 2020",Covid19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04448756,Recruiting,"July 29, 2020","November 13, 2020",Coronavirus Disease 2019,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:70 Years",No,150
NCT04325633,Not yet recruiting,"April 13, 2020","July 13, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,584
NCT04497922,Not yet recruiting,"August 20, 2020","April 17, 2021","Satisfaction, Patient,Covid19,Emergencies,Satisfaction,Information Disclosure","Randomized,Parallel Assignment,Randomized controlled trial,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04549337,Not yet recruiting,"September 25, 2020","May 1, 2021",COVID-19,"Randomized,Crossover Assignment,This study uses a randomized crossover trial testing the feasibility of 3 different training protocols.,Prevention,Double (Participant, Outcomes Assessor),Participants are randomly allocated following successful completion of the baseline measurements. A researcher, that is not involved in testing or training procedures, generates a computer-generated block randomization schedule with balanced permutations. To ascertain allocation concealment, the block sizes will not be disclosed. The schedule is forwarded to a research assistant, who is not involved in any study procedures and stored on a password protected computer. Following the baseline measurements, the participants are given consecutive numbers. These are forwarded to the research assistant, who returns the corresponding allocation sequence to the study coordinator. The participants are blinded for treatment allocation until treatment assignment. However, following the initial two treatments blinding of the participants is no longer possible. All study personal involved with data collection will be blinded during baseline testing.","gender:All,Min Age:40 Years,Max Age:N/A",No,10
NCT04359459,Not yet recruiting,June 2020,June 2022,COVID-19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04405466,Recruiting,"April 22, 2020","January 31, 2021",COVID-19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04416308,Recruiting,"May 29, 2020","October 10, 2020",Coronavirus,"Non-Randomized,Parallel Assignment,This is a multi-center cross-sectional survey at risk and minimal constraints, among GHT Haute Bretagne employees in order to know the prevalence of the presence of anti-SARS-CoV-2 antibodies.
For a sample of employees with no additional prospective follow-up will be done on D30 and D90.,Diagnostic,Single (Outcomes Assessor),For the first 30 employees a second test will be carried out a few minutes after the first test by another nurse blinded to the result of the first test in order to estimate the agreement between - observers.","gender:All,Min Age:18 Years,Max Age:N/A",No,13000
NCT04455815,Recruiting,"September 25, 2020","August 31, 2021",COVID-19 Infection,"Randomized,Sequential Assignment,Treatment,None (Open Label)","gender:All,Min Age:50 Years,Max Age:N/A",No,389
NCT04473248,Recruiting,"June 28, 2020","August 1, 2020",Covid19,"Non-Randomized,Single Group Assignment,Each Patient enrolle dint he study will experience the same modes of sample collection and sample analysis.,Diagnostic,Single (Participant),The results of the Spartan COVID-19 System tests will not be shared with the participant or the lab, but the lab results will be shared with Spartan once analysis of the Spartan System samples is complete.","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04530370,Recruiting,"May 29, 2020","September 1, 2020",Covid19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04355936,Recruiting,"May 19, 2020","October 1, 2020",COVID-19 Drug Treatment,"Randomized,Parallel Assignment,Patients will be randomized to receive standard care or standard care plus Telmisartan 80 mg twice daily upon diagnosis of COVID-19.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04354597,Not yet recruiting,"May 1, 2020","October 15, 2020",COVID-19,"Randomized,Parallel Assignment,Subjects who are enrolled in the study will be randomly assigned to any of the study arms, A or B.
Study Arm A (HCQ & AZ)
Study Arm B (No treatment),Prevention,None (Open Label)","gender:All,Min Age:25 Years,Max Age:70 Years",No,200
NCT04510025,Recruiting,"May 13, 2020","May 1, 2023","Coronavirus Infection,Multi-Organ Disorder","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,616
NCT04322513,Recruiting,"March 24, 2020","December 30, 2020",Coronavirus,"Case-Control,Prospective","sampling_method:Probability Sample,gender:All,Min Age:14 Years,Max Age:75 Years",No,110
NCT04338672,Recruiting,"April 5, 2020","April 1, 2022","Emergency Service, Hospital,General Surgery","Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,10000
NCT04394208,Recruiting,"August 16, 2020","February 28, 2021","COVID-19,Viral Pneumonia Human Coronavirus","Randomized,Parallel Assignment,Group 1 (Control): Includes 25 patients with COVID-19 pneumonia receiving standard of care as per Ministry of Health Protocol of Treatment + placebo Group 2 (Intervention): Includes 25 patients with COVID-19 pneumonia receiving standard of care as per Ministry of Health Protocol of Treatment + Silymarin Oral at a dose of 420 mg/day in 3 divided doses.,Treatment,Double (Participant, Care Provider)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04326426,Enrolling by invitation,"April 13, 2020","August 31, 2020",Coronavirus Infection,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:90 Years",N/A,300
NCT04419623,Recruiting,"July 9, 2020",July 2021,"COVID-19,Sars-CoV2,Cancer,Solid Tumor,Carcinoma,Blood Cancer","Randomized,Single Group Assignment,In Part 1, up to 18 subjects will participate in a dose-finding safety lead-in to determine the recommended TL-895 dose.
In Part 2, 64 subjects will be randomized to the recommended TL-895 dose w/ SAT (Arm 1), and 64 subjects will be randomized to Placebo w/ SAT (Arm 2).,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),The control product in this study is placebo. The placebo will only be used in Part 2. Placebo will be matched in appearance and packaging to active investigational product TL-895.
Investigators and Sponsor will be blinded to each subject's assigned study treatment in Part 2 (the double-blind, placebo-controlled portion of the study) via unique kit numbers on study drug cartons.","gender:All,Min Age:18 Years,Max Age:N/A",No,146
NCT04397666,Recruiting,"May 15, 2020","November 15, 2020","SARS-CoV Infection,Pinkeye","N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,68
NCT04480411,Not yet recruiting,October 2020,February 2021,"Diagnoses Disease,Covid19","Non-Randomized,Parallel Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,165
NCT04405921,Not yet recruiting,July 2020,March 2021,"SARS-CoV-2 Pneumonia,COVID-19","Randomized,Parallel Assignment,Treatment,Double (Participant, Care Provider)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04367129,Recruiting,"April 14, 2020","December 1, 2021",SARS-CoV Infection,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,1000
NCT04416919,Recruiting,"July 15, 2020",May 2025,"Coronavirus Infection,Disease Prevention","N/A,Single Group Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04443881,Recruiting,"May 8, 2020",March 2021,COVID-19 Pnemonia,"Randomized,Parallel Assignment,A phase 2/3, randomized, open label, parallel group, 2-arm, multicenter study investigating the efficacy and safety of intravenous administrations of the study drug,,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,180
NCT04366245,Recruiting,"April 23, 2020",December 2021,SARS-CoV 2,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,72
NCT04492228,Recruiting,"September 1, 2020","May 30, 2021","Covid19,Ketogenic Dieting","Randomized,Parallel Assignment,This is a controlled, randomized, open-label, clinical trial designed to determine whether a ketogenic diet,in comparison with a standard diet, improves mortality and reduces ventilator requirements or ICU access in patients with coronavirus disease.
The study team will prospectively enroll 50 patients with COVID-19 infection administering a 4:1 ratio ketogenic formula (both enteral or parenteral) and 50 with standard diet,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04357613,Not yet recruiting,"September 1, 2020","December 1, 2021",SARS Virus,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:70 Years,Max Age:N/A",No,99
NCT04327349,Enrolling by invitation,"March 28, 2020","September 30, 2020",Coronavirus Infections,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:30 Years,Max Age:70 Years",No,30
NCT04425720,Not yet recruiting,"August 31, 2020","June 1, 2021",COVID,"Randomized,Parallel Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:90 Years",No,300
NCT04542850,Not yet recruiting,November 2020,December 2020,"SARS-CoV 2,COVID-19","N/A,Single Group Assignment,This is an open label pilot study involving 40 patients with COVID-19 disease. Patients that are hospitalized due to confirmed SARS-CoV-2 infection will be assigned to two groups according o their severity grade (moderate or severe).,Treatment,None (Open Label)","gender:All,Min Age:21 Years,Max Age:N/A",No,40
NCT04569786,Not yet recruiting,"October 22, 2020","December 3, 2021",Coronavirus Disease (COVID-19),"Randomized,Sequential Assignment,Prevention,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,252
NCT04411459,Recruiting,"February 1, 2020","October 30, 2020","COVID-19,Mechanical Ventilation,Quality of Life,Radiologic Increased Density of Lung,Sedation,Complication of Treatment","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,600
NCT04374032,"Active, not recruiting","May 1, 2020","December 31, 2020",COVID-19 Infection,"Randomized,Parallel Assignment,Open-label, prospective, randomized, comparative, multiple doses applied in addition to the standard of care treatment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04457349,Recruiting,"July 25, 2020","December 29, 2020",COVID 19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,10
NCT04338568,Recruiting,"April 16, 2020","December 30, 2020","COVID-19 Pneumonia,Lung Ultrasound","Non-Randomized,Single Group Assignment,Patients with the diagnosis of COVID-19 pneumonia will undergo a lung ultrasound, by two observers each. The findings will be compared with findings on chest x-ray and/or CT thorax. Accuracy and inter-observer variability will be calculated.,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04426006,Not yet recruiting,June 2020,December 2021,"Sars-CoV2,Serum; Disease","N/A,Single Group Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04519034,Not yet recruiting,"September 1, 2020","December 31, 2020",Covid19,"Other,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:1 Year,Max Age:100 Years",No,27000
NCT04551339,Enrolling by invitation,"September 28, 2020","May 14, 2021","Healthy,Health Care Worker Patient Transmission,Aging","Randomized,Parallel Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:90 Years",No,4500
NCT04346797,Recruiting,"April 16, 2020","December 31, 2020","SARS-CoV-2,COVID19","Randomized,Parallel Assignment,Bayesian open labelled randomized clinical trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,120
NCT03891420,Recruiting,"April 9, 2020","May 31, 2021","COVID-19,Yellow Fever","Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,132
NCT04391166,"Active, not recruiting","May 20, 2020","May 1, 2022",Visual Impairment,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:90 Years",No,150
NCT04348864,Recruiting,"April 16, 2020",April 2021,"Communicable Disease,COVID-19,Sars-CoV2,Infectious Disease,Coronavirus,Virus","Non-Randomized,Parallel Assignment,Subject that have experienced symptoms consistent with COVID-19 and have been tested by polymerase chain reaction (PCR) or clinical diagnosis and have been determined to be positive or negative will undergo self-testing for antibodies. Roughly equal numbers of positive or negative subjects will participate in self-testing.,Diagnostic,None (Open Label),Participants are aware of their diagnosis prior to testing the antibody test. They will see the result of the self-test between 10-20 minutes after performing the test.","gender:All,Min Age:18 Years,Max Age:99 Years",No,100
NCT04573153,Recruiting,"September 21, 2020","March 31, 2021",COVID-19,"Randomized,Parallel Assignment,This study was planned as a parallel group, randomized and open label study. The subjects will be randomized on a 3:1 basis to the cofactor supplementation combination plus hydroxychloroquine treatment or hydroxychloroquine +placebo treatment.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04400461,Recruiting,"May 15, 2020","November 15, 2020",COVID-19,"Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,50
NCT04324489,Completed,"March 6, 2020","April 30, 2020",COVID-19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,4
NCT02765191,Recruiting,April 2016,October 2025,"Sepsis, Severe,Acute Kidney Injury,COVID-19","N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04413058,Recruiting,"April 10, 2020","November 10, 2020","Menstrual Irregularity,Covid 19","Case-Crossover,Prospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:47 Years",No,200
NCT04475081,Not yet recruiting,"August 17, 2020","December 1, 2021",Sepsis Syndrome,"Randomized,Parallel Assignment,MMR vaccine vs placebo,Prevention,Single (Participant),Randomized by study nurse","gender:All,Min Age:18 Years,Max Age:70 Years",No,60
NCT04370288,Recruiting,"April 19, 2020","September 21, 2020",Covid-19,"Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:90 Years",No,20
NCT04459390,Recruiting,"July 20, 2020","November 20, 2020",COVID19,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04464408,Recruiting,"July 23, 2020",June 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:100 Years",No,576
NCT04363463,Not yet recruiting,November 2020,May 2022,"COVID19,Oxygen Therapy,Prone Position,Spontaneous Ventilation,Respiratory Distress Syndrome","Randomized,Parallel Assignment,Randomized controlled multicenter trial Ratio 1:1,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:85 Years",No,400
NCT04516915,Recruiting,"June 15, 2020",July 2021,Covid 19,"Randomized,Parallel Assignment,Prospective, Randomized, Parallel-Group, Open-Label Study,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:90 Years",No,120
NCT04347174,Recruiting,"April 30, 2020","July 30, 2020",COVID-19,"Randomized,Parallel Assignment,Randomized, blinded, two arms, active comparator controlled, clinical trial,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Investigator, patient and study staff will be blinded to the study treatment.","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04498091,"Active, not recruiting","March 15, 2020",July 2021,Acute Myocardial Infarction,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,35
NCT04453969,Recruiting,"May 24, 2020",January 2021,"SARS-CoV2,Breastmilk","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,50
NCT04379518,Recruiting,"September 4, 2020","September 4, 2021","Malignant Neoplasm,SARS Coronavirus 2 Infection","N/A,Single Group Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,44
NCT04341038,Recruiting,"April 1, 2020","July 1, 2020","COVID-19,Lung Injury","Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor),The statistician who will finally carry out the analyses will be blind to the treatment received by the patients","gender:All,Min Age:18 Years,Max Age:N/A",No,84
NCT04541680,Not yet recruiting,September 2020,December 2021,SARS-Cov-2 Induced Pulmonary Fibrosis,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:89 Years",No,250
NCT04522089,Recruiting,"August 24, 2020","March 20, 2021",COVID-19,"Randomized,Sequential Assignment,Prevention,None (Open Label)","gender:All,Min Age:20 Years,Max Age:60 Years",No,70
NCT04399005,Completed,"May 25, 2020","June 10, 2020","Daily Room Disinfection,After-each-case Room Disinfection","Non-Randomized,Parallel Assignment,Other,Single (Outcomes Assessor)","gender:All,Min Age:N/A,Max Age:N/A",No,240
NCT04568655,Completed,"February 1, 2020","July 1, 2020",Noninvavie Ventilation to Patients With COVID-19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:20 Years,Max Age:80 Years",No,23
NCT04400838,Recruiting,"May 28, 2020",August 2021,Coronavirus,"Randomized,Sequential Assignment,Prevention,Single (Participant)","gender:All,Min Age:5 Years,Max Age:N/A",No,12330
NCT04357834,Not yet recruiting,"May 1, 2020","July 31, 2020","COVID,COVID 19,SARS-CoV 2","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:120 Years",No,100
NCT04559542,Recruiting,"September 10, 2020","December 31, 2020","Body Weight Changes,Eating Disorder Symptom,Sexual Harassment,Covid19,RED S","Cohort,Cross-Sectional","sampling_method:Probability Sample,gender:Female,Min Age:16 Years,Max Age:40 Years",No,200
NCT04273529,Not yet recruiting,"February 20, 2020","June 30, 2020",COVID-19 Thalidomide,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04355052,Recruiting,"April 11, 2020","December 11, 2020",COVID - 19,"Randomized,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:120 Years",No,250
NCT04355637,Recruiting,"April 21, 2020","October 18, 2020",Coronavirus Infection,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:79 Years",No,300
NCT04387292,Recruiting,"September 7, 2020",May 2021,"COVID19,Ophthalmopathy","N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04354701,Recruiting,"March 17, 2020",December 2022,"COVID-19,Invasive Malignancy (Any Type)","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,10000
NCT04558411,Recruiting,"September 12, 2020","December 15, 2020","Emotional Regulation,Affect","Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04355143,Recruiting,"May 1, 2020","April 25, 2021",COVID-19,"Randomized,Parallel Assignment,Random assignment to study arms in a 1:1 ratio,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04413864,Recruiting,"April 24, 2020","February 28, 2021",SARS-CoV 2,"N/A,Single Group Assignment,open-label monocentric cohort study, with intervention added,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04407923,Recruiting,"May 25, 2020","November 25, 2020","Juvenile Idiopathic Arthritis,COVID 19,Treatment","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:17 Years",No,150
NCT04358783,Recruiting,"April 27, 2020","May 30, 2021",Coronavirus Infection,"Randomized,Parallel Assignment,RCT double blind comparative study,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),double blind","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04525716,Recruiting,"March 1, 2020","December 31, 2020","Covid19,Surgery","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,2000
NCT04399603,Not yet recruiting,"May 18, 2020","November 17, 2021",COVID,"Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:90 Years",No,120
NCT04419870,Recruiting,"October 12, 2020","May 1, 2025",Mitochondrial Disease,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:2 Months,Max Age:N/A",No,200
NCT04330144,Not yet recruiting,"April 1, 2020","March 30, 2022",Contact Person From COVID-19 Confirmed Patient,"Randomized,Parallel Assignment,Prevention,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:99 Years",No,2486
NCT04539795,Not yet recruiting,"October 1, 2020","September 30, 2021",Covid19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,15
NCT04401163,Not yet recruiting,May 2020,December 2022,"Sars-CoV2,Covid19","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:85 Years",No,180
NCT04389411,Not yet recruiting,"October 1, 2020",December 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:40 Years,Max Age:N/A",No,600
NCT04385836,Recruiting,"June 1, 2020","September 1, 2020",Coronavirus,"Randomized,Parallel Assignment,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04378712,Completed,"January 21, 2020","March 23, 2020","Covid-19,Hydrogen/Oxygen Mixed Gas,Dyspnea","Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,90
NCT04561076,Not yet recruiting,"December 9, 2020","September 18, 2021",COVID 19,"Randomized,Sequential Assignment,Other,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double-Blind, Placebo-Controlled","gender:All,Min Age:18 Years,Max Age:60 Years",No,24
NCT04385264,Not yet recruiting,"May 12, 2020",October 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,800
NCT03852537,Recruiting,"December 2, 2019",July 2022,Pneumonia,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,90
NCT04530409,Recruiting,"August 26, 2020","November 1, 2020","Covid19,Corticosteroids","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,450
NCT04394429,Recruiting,"April 24, 2020","June 24, 2020",Sars-CoV2,"Case-Only,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,184
NCT04433871,Recruiting,"April 27, 2020","April 27, 2023","Covid-19,Cancer","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:1 Month,Max Age:30 Years",No,300
NCT04339322,Not yet recruiting,"May 1, 2020","July 30, 2020","Characteristics Diseases,Outcome, Fatal","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,200
NCT04403438,Enrolling by invitation,"April 1, 2020","June 15, 2020","Behcet Disease,COVID,FMF","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:65 Years",No,45
NCT04568031,Recruiting,"August 23, 2020","September 6, 2021",COVID-19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:N/A,Max Age:N/A",No,12
NCT04372030,Not yet recruiting,"May 1, 2020","October 31, 2021",Health Care Utilization,"N/A,Single Group Assignment,This is an online survey completed by participants willing to take part,Health Services Research,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,10000
NCT04445337,Not yet recruiting,July 2020,July 2021,"COVID 19,ARDS","N/A,Single Group Assignment,Open-label use of stellate ganglion block.,Treatment,None (Open Label)","gender:All,Min Age:19 Years,Max Age:85 Years",No,10
NCT04348552,Recruiting,"April 28, 2020","June 28, 2020",Patient Safety,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1000
NCT04561024,"Active, not recruiting","March 1, 2020","December 31, 2020",Covid19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:120 Years",No,4000
NCT04372602,Not yet recruiting,"September 30, 2020","March 31, 2022",COVID-19,"Randomized,Single Group Assignment,Treatment,Triple (Participant, Care Provider, Investigator),Blocks of 10 patients will be used to allocate patients to duvelisib or placebo","gender:All,Min Age:18 Years,Max Age:N/A",No,28
NCT04393727,Recruiting,"May 1, 2020","October 30, 2020","COVID,SARS-CoV 2","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,126
NCT04403243,Recruiting,"May 8, 2020","August 23, 2020",COVID 19,"Randomized,Parallel Assignment,Patients will be randomized 3:1:1:3 into four groups: colchicine, ruxolitinib, secukinumab, and control group,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,70
NCT04278404,Recruiting,"March 5, 2020","April 24, 2024","Coronavirus Infection (COVID-19),Pulmonary Arterial Hypertension,Urinary Tract Infections in Children,Hypertension,Pain,Hyperphosphatemia,Primary Hyperaldosteronism,Edema,Hypokalemia,Heart Failure,Hemophilia,Menorrhagia,Insomnia,Pneumonia,Skin Infection,Arrythmia,Asthma in Children,Bronchopulmonary Dysplasia,Adrenal Insufficiency,Fibrinolysis; Hemorrhage,Attention Deficit Hyperactivity Disorder,Multisystem Inflammatory Syndrome in Children (MIS-C),Kawasaki Disease,Coagulation Disorder,Down Syndrome","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:20 Years",No,5000
NCT04438863,Not yet recruiting,"September 1, 2020","September 1, 2021",COVID 19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:85 Years",No,90
NCT04382196,"Active, not recruiting","April 17, 2020","December 31, 2022","Mental Health,Quality of Life","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,497
NCT04344977,Recruiting,"June 1, 2020","April 1, 2025",Coronavirus Disease 2019 (COVID-19),"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:70 Years",No,1500
NCT04406324,Recruiting,"June 1, 2020","March 5, 2026",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04445428,Enrolling by invitation,"July 15, 2020",June 2021,"Poliovirus Vaccine, Oral,COVID,Mortality,Morbidity,Non-Specific Effects of Vaccines","Randomized,Parallel Assignment,Prevention,Double (Care Provider, Outcomes Assessor),Participants are cluster randomised to OPV or no vaccine. Information on group assignment is not available to health center staff and staff at the health and demographic surveillance system","gender:All,Min Age:50 Years,Max Age:N/A",No,3400
NCT04556630,Not yet recruiting,October 2020,December 2020,Assisted Reproduction,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,360
NCT04394013,Recruiting,"August 26, 2020",December 2020,Mental Health Issue,"Randomized,Parallel Assignment,Supportive Care,Triple (Participant, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,70
NCT04483960,Recruiting,"July 21, 2020","June 12, 2022",SARS-CoV-2 Infection (COVID-19),"Randomized,Factorial Assignment,Participants enrolled into the study have the option of deciding whether to be randomised in one or both (if available) treatment domains concurrently, if they meet the eligibility criteria.,Treatment,None (Open Label),This is an open-label study.","gender:All,Min Age:18 Years,Max Age:N/A",No,2400
NCT04351880,Recruiting,"April 16, 2020",July 2021,"Heart Failure,Copd,Liver Failure,Covid19,Diabetes Mellitus,Cancer,End Stage Renal Disease","Randomized,Parallel Assignment,This is a randomized trial to compare two approaches to meal delivery. Group 1 will receive meal delivery for 2 weeks (1 meal per day for a total of 14 days) and Group 2 will receive meal delivery for 4 weeks (1 meal per day for a total of 28 days). A concurrent propensity matched control group which will not receive an intervention will also be used.,Other,Single (Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,640
NCT04365985,Recruiting,"April 29, 2020",August 2021,"COVID-19,Acute Respiratory Distress Syndrome,Severe Acute Respiratory Syndrome (SARS),Coronavirus Infections","Randomized,Factorial Assignment,Prospective, single center, randomized, double blinded study of naltrexone with an open label extension using ketamine as a rescue drug for patients who progress in their disease,Treatment,Triple (Participant, Care Provider, Investigator),No other parties blinded","gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04436458,Not yet recruiting,December 2020,April 2021,COVID,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04260594,Not yet recruiting,"February 7, 2020","December 30, 2020",2019-nCoV,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,380
NCT04395924,Recruiting,"May 5, 2020",May 2021,"Maternal Fetal Infection Transmission,COVID-19,SARS-CoV 2","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:48 Years",No,50
NCT04427332,Recruiting,"May 15, 2020","September 30, 2020",covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04537962,Enrolling by invitation,"June 11, 2020","August 30, 2021",Corona Virus Infection,"Randomized,Factorial Assignment,Supportive Care,Single (Participant)","gender:All,Min Age:18 Years,Max Age:90 Years",No,70
NCT04439045,Recruiting,"June 24, 2020","July 1, 2021",SARS-CoV-2 Infection,"Randomized,Parallel Assignment,Prevention,Double (Participant, Care Provider),The clinical trial is designed as a double-blind (observer blind) study. Observer-blind means that during the course of trial, the companions/parents/guardians of the subjects and the study personnel responsible for the evaluation of any study endpoint will be unaware which vaccine was administered.","gender:All,Min Age:18 Years,Max Age:N/A",No,3626
NCT04492501,Completed,"April 1, 2020","July 20, 2020","Covid19,Cytokine Release Syndrome,Critical Illness,ARDS","Non-Randomized,Factorial Assignment,It will be an interventional retrospective case control, single centre based cohort study in Pak Emirates Military Hospital Rawalpindi (PEMH), Pakistan from 1st April to 31st July 2020. This study will be carried out at the Department of Pulmonology and Critical care. PEMH is the largest Covid-19 designated hospital in the country. Data of all hospitalized patients is maintained by PEMH Covid-19 Research and evaluation cell. The study was approved by Institutional Review Board.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:90 Years",No,600
NCT04414293,Not yet recruiting,"October 1, 2020","March 31, 2021","COVID,Pneumonia, Viral","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:65 Years,Max Age:N/A",No,41
NCT04401150,Recruiting,"August 14, 2020",January 2022,"Vitamin C,COVID-19,Hospitalized Patients","Randomized,Parallel Assignment,Randomized controlled trial,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Only the pharmacist of the participating site will be unblinded for the preparation of the study drug to be administered.","gender:All,Min Age:18 Years,Max Age:N/A",No,800
NCT04340414,Recruiting,"February 20, 2020","October 15, 2020","COVID-19,ECMO","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:14 Years,Max Age:N/A",No,10
NCT04378452,Recruiting,"March 31, 2020",December 2020,"SARS-CoV 2,COVID-19,Quality of Life,Mental Health Wellness 1,Social Distance,SARS (Disease),Psychological","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:16 Years,Max Age:N/A",No,65000
NCT04459520,Completed,"July 23, 2020","July 29, 2020",COVID-19,"Randomized,Parallel Assignment,Parallel 3-arm, cross-sectional, behavioral intervention study,Screening,None (Open Label),Open label (participants will be randomized to receive different scenarios, but will not be aware of the other two scenario types)","gender:All,Min Age:18 Years,Max Age:110 Years",No,1400
NCT04453501,Completed,"March 2, 2020","April 25, 2020","COVID,Pneumonia, Viral","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,132
NCT04427176,Completed,"April 29, 2020","May 28, 2020",Nurse,"Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,15
NCT04533399,Recruiting,"August 17, 2020",November 2021,"SARS-CoV-2 Infection,COVID-19","Randomized,Sequential Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:64 Years",No,2904
NCT04319731,Recruiting,"March 20, 2020","March 20, 2021",SARS CoV-2 Infection,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,10
NCT04382235,"Active, not recruiting","March 26, 2020","June 30, 2020",Covid-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,900
NCT04553575,Recruiting,"September 25, 2020",September 2022,Coronavirus Infections,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,499
NCT04347954,Recruiting,"August 15, 2020",January 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,45
NCT04337151,Recruiting,April 2020,March 2021,MAGEC Rod,"Case-Control,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04395430,Not yet recruiting,"September 1, 2020",October 2021,"Pediatric Obesity,Clinical Trial","Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:4 Years,Max Age:6 Years",No,40
NCT04482023,Not yet recruiting,September 2020,"December 31, 2020",COVID-19,"Case-Only,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04320953,Completed,"March 16, 2020","April 9, 2020","Gastrointestinal Disease,Infectious Disease","N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,5
NCT04539275,Not yet recruiting,"October 19, 2020","June 30, 2022",COVID-19,"Randomized,Parallel Assignment,There are two study treatment arms: convalescent plasma versus saline. Participants will be randomized in 1:1 ratio to these two arms.,Treatment,Triple (Participant, Care Provider, Investigator),The participants, site investigators, clinical prescribers, site coordinators, and most other individuals involved in this study will be blinded to the treatment assignment.
Furthermore, the blind will not routinely be broken in order to select post-study, pharmacologic treatment for SARS-CoV-2 infection administered by clinical healthcare providers.","gender:All,Min Age:18 Years,Max Age:N/A",No,702
NCT04424056,Not yet recruiting,"September 1, 2020","November 1, 2022",Covid19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,216
NCT04359264,"Active, not recruiting","April 20, 2020","December 30, 2020",COVID-19,"Randomized,Parallel Assignment,Prevention,Double (Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,392
NCT04569227,Not yet recruiting,"October 6, 2020",November 2021,Covid19 Pneumonia,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,60
NCT04354558,Recruiting,"July 1, 2020",August 2021,"Epidemiology,Sars-CoV2,COVID 19,Critical Care,Prognostic,Survival","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04431414,Recruiting,"July 20, 2020",January 2021,"SARS-CoV-2,COVID-19","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,800
NCT04424446,Recruiting,"July 13, 2020","June 1, 2021",COVID-19,"Case-Only,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,5000
NCT04368234,Recruiting,"April 18, 2020","April 30, 2025",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100000
NCT04416061,"Active, not recruiting","May 25, 2020","August 31, 2020",COVID,"Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,2500
NCT04337541,Completed,"April 2, 2020","June 2, 2020",COVID-19,"Randomized,Parallel Assignment,The participants recruited are people working outside of their home, who have not previously been infected with COVID-19 and who do not wear facial masks (e.g. healthcare personnel) when working. They will be randomized for
Normal behavior according to the authority's recommendations or
Normal behavior according to the authority's recommendations and use of facial masks
Participants will be instructed in using the facial mask consistently when outside their home (and at home when receiving visits from others. The instruction is given in writing and via an instruction video. The participants will be contacted once weekly to optimize compliance. It will be registered if the participants are diagnosed with COVID-19. Participants will perform antibody screening at study start and end. Participants, who are not tested positive for COVID-19 in the study period will perform a swab self-test if experiencing symptoms or when the study ends (instruction video).,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,6000
NCT04427735,Recruiting,"January 24, 2019","July 24, 2021",STEMI,"Case-Crossover,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,200
NCT04333407,Recruiting,"April 3, 2020","March 30, 2021",COVID-19,"Randomized,Parallel Assignment,Prospective Multicentre Randomised Controlled Trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:85 Years",No,3170
NCT03226886,Recruiting,"February 5, 2012","September 1, 2023","Renal Cell Carcinoma,Cancer,Healthy Volunteers","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,360
NCT04453527,Recruiting,"May 28, 2020",September 2021,Coronavirus,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04410016,Recruiting,"May 25, 2020","November 30, 2020",Mental Health Wellness 1,"N/A,Single Group Assignment,All staff have access to the Staff Wellbeing Centres (usual practice). In this study the investigators will conduct a questionnaire survey with all Nottingham University Hospitals National Health Service (NHS) staff about their mental wellbeing, and use of this facility. The investigators will conduct qualitative interviews with users and non-users of the Wellbeing Centres (staff) as well as the Wellbeing Buddies (support workers).,Other,None (Open Label),This is an evaluation of a service - the Wellbeing Centres at Nottingham University Hospitals National Health Service (NHS) Trust - which are a form of 'intervention' for staff provided during the coronavirus pandemic. Therefore the investigators will conduct interviews with people who have used the centres, or who have acted as support workers within them. The investigators will survey all staff in the Trust, and interview up to 45 participants.","gender:All,Min Age:N/A,Max Age:N/A",No,45
NCT04550351,Recruiting,"August 19, 2020","December 31, 2021",Coronavirus,"Randomized,Sequential Assignment,Prevention,Single (Participant)","gender:All,Min Age:60 Years,Max Age:N/A",No,50
NCT04509752,Not yet recruiting,"August 20, 2020","November 30, 2020","Dysphagia,Covid19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:25 Years,Max Age:60 Years",No,50
NCT04337346,Completed,"April 5, 2020","April 25, 2020","Endometriosis,Covid19","Case-Control,Prospective","sampling_method:Probability Sample,gender:Female,Min Age:18 Years,Max Age:45 Years",No,80
NCT04492943,Completed,"April 20, 2020","June 30, 2020",COVID-19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,35
NCT04460170,Recruiting,"July 1, 2020","February 1, 2022","Quality of Life,COVID-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04540185,Enrolling by invitation,"November 1, 2020","December 31, 2022","Covid19,SARS (Severe Acute Respiratory Syndrome),SARS-CoV Infection,SARS-CoV-2","Randomized,Parallel Assignment,Parallel assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,3600
NCT04321993,Recruiting,"April 17, 2020",March 2022,COVID-19,"Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,800
NCT04495816,Recruiting,"July 15, 2020",June 2021,"Anosmia,Covid19","Randomized,Parallel Assignment,Patients will be randomized into treatment and control groups. The treatment group will receive omega-3-fatty acid supplementation (1000 mg of omega-3 fatty acid blend including 683 mg Eicosapentaenoic Acid and 252 mg Docosahexaenoic Acid) to be taken twice daily for 6 weeks. The control arm will receive a placebo pill to be taken twice daily.,Treatment,Double (Participant, Investigator),The healthcare providers interacting with the patients, as well as the participants themselves, will not know which arm they have been assigned to. Only the research fellows will have access to the randomization scheme.","gender:Female,Min Age:18 Years,Max Age:N/A",No,126
NCT04447404,Recruiting,"September 21, 2020",October 2021,SARS-CoV 2,"Randomized,Parallel Assignment,3:1 randomization DUR-928:placebo,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:80 Years",No,80
NCT04418557,Recruiting,"April 28, 2020","July 31, 2021","COVID,Pregnancy Complications","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:50 Years",No,200
NCT04475588,Completed,"May 1, 2020","July 8, 2020","Acute Respiratory Distress Syndrome,Cytokine Release Syndrome,Covid19","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:99 Years",No,30
NCT04480398,Completed,"May 12, 2020","July 3, 2020","Covid19,Asymptomatic Condition","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:75 Years",No,91
NCT04334980,Not yet recruiting,October 2020,"February 28, 2022",COVID-19,"N/A,Single Group Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,12
NCT04427813,Not yet recruiting,"June 11, 2020","July 12, 2020",Sexual Behavior,"Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:60 Years",No,400
NCT04456556,Completed,"April 27, 2020","June 30, 2020",Endophthalmitis and Orbital Cellulitis,"Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,5
NCT04361253,Recruiting,"April 30, 2020",December 2021,"COVID,Infectious Disease","Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:12 Months,Max Age:N/A",No,220
NCT04345640,Recruiting,"April 10, 2020","December 31, 2020",Liver Cirrhoses,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:70 Years",No,1000
NCT04448782,Completed,"March 9, 2020","June 30, 2020",Mechanical Ventilation Complication,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,32
NCT04558645,Recruiting,"September 18, 2020","December 18, 2020","Type 1 Diabetes Mellitus,Covid19","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:65 Years",No,70
NCT04420364,Not yet recruiting,"July 1, 2020","December 31, 2021","COVID,Kidney Transplant; Complications,Immunosuppression","Randomized,Parallel Assignment,Single-blind, parallel-group, randomized, active-controlled trial,Treatment,Single (Outcomes Assessor),This is a single-blind trial, in that only the assessor will be blinded to the treatment assignment.","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04401228,"Active, not recruiting","March 1, 2020","January 1, 2021","COVID19,Pneumonia, Viral,Inflammatory Response","Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04388683,Recruiting,"May 12, 2020","July 31, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:85 Years",No,42
NCT04408027,Not yet recruiting,"June 1, 2020","June 1, 2021",Anxiety Disorder of Childhood or Adolescence,"N/A,Single Group Assignment,The current study will leverage an adapted virtual-care cognitive behavioural therapy program for children with anxiety (VC-CBT). The VC-CBT protocol will involve 12 sessions (of one hour in duration) delivered by a CBT therapist using PHIPA (Personal Health Information Protection Act) compliant Zoom. An initial session will review therapy goals and psychoeducation about anxiety. Sessions 2 and 3 will focus on feeling identification and will introduce relaxation strategies. Sessions 4 and 5 will introduce cognitive distortions and restructuring strategies. Sessions 6 and 7 will introduce exposure tasks. Sessions 8 to 11 will involve practicing cognitive restructuring skills and completing exposures. The final session will review relapse prevention. Parents will participate in the first and last sessions, as well as join at the end of each session for a brief review of the skills learned during the session.,Treatment,None (Open Label)","gender:All,Min Age:12 Years,Max Age:17 Years",No,20
NCT04482699,Not yet recruiting,"November 30, 2020","February 28, 2022",Severe COVID-19 Disease,"Randomized,Sequential Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,88
NCT04539873,Not yet recruiting,September 2020,December 2020,Corona Virus Infection,"Randomized,Parallel Assignment,This is a phase IIIa, prospective, open-label, randomized, parallel-group study designed to evaluate the efficacy and safety of oral colchicine plus standard therapy versus standard therapy in the clinical course of SARS-CoV-2 infection, in a population group with moderate COVID-19 compromise and requiring hospitalization.
Patients diagnosed with COVID-19 and meeting all eligibility criteria will be randomized for treatment in a 1: 1 ratio through a central voice response system. Randomization will be balanced in each of the 2 strata: 1) hospitalized patients with clinical stage 4 (requirement of supplemental oxygen by nasal contact lenses or mask) of the World Health Organization (WHO) classification, see ANNEX 2, who will receive in addition to the usual treatment for COVID-19 oral colchicine (exposed group); 2) hospitalized patients with clinical stage 4 of the WHO classification who will receive the usual treatment for COVID-19 (control group).,Treatment,Single (Participant),the sample size of 120 subjects each arm of 60 subjects. Random assignment (1: 1) to either colchicine plus standard treatment or control arm (standard treatment) orally for 14 days. An initial dose of 1.5 mg orally on the first day, followed by 0.5 mg every 12 hours on days 2 to 7 and continuing with 0.5 mg a day until completing 14 days ± 1. It will be followed on days 1, 3, 7, 14, and day 28, evaluating physical examination, clinical situation, laboratories, and adverse events. The primary efficacy data correspond to the deterioration in the clinical status of the patients through the semiquantitative ordinal scale suggested by the WHO R&D committee. Expected results: It is expected to find out how, through different pathways, colchicine could act in modulating or preventing","gender:All,Min Age:18 Years,Max Age:N/A",No,128
NCT04447209,Recruiting,"June 6, 2020","May 31, 2021",Dietary Diversity,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:6 Months,Max Age:6 Years",No,300
NCT04573855,Not yet recruiting,"December 1, 2020","March 31, 2021",Covid19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,41
NCT04328441,"Active, not recruiting","March 25, 2020","April 30, 2021",COVID-19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Unblinded are the pharmacist and the research nurse that administers the study medication. These persons are not involved in the further conduction of the trial or in the assessment of outcomes.","gender:All,Min Age:18 Years,Max Age:N/A",No,1500
NCT04508933,Not yet recruiting,"September 1, 2020","December 31, 2020","Respiratory Distress Syndrome, Adult,Ventilation Perfusion Mismatch,Pulmonary Edema,Covid19","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,10
NCT04431466,Recruiting,"July 1, 2020","July 1, 2021",Coronavirus Infection,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,64
NCT04356950,Recruiting,"April 28, 2020",January 2021,"Sepsis,Blood Coagulation Disorders,Thrombin,Disseminated Intravascular Coagulation,COVID-19","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,175
NCT04372589,Recruiting,"May 20, 2020",January 2021,"COVID-19,Pneumonia","Randomized,Parallel Assignment,Pragmatic, Bayesian adaptive randomized controlled trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,3000
NCT04511429,Recruiting,"June 30, 2020",April 2021,"Infections, Coronavirus,Kidney Transplantation,Liver Transplantation,Cancer,Covid19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:1 Month,Max Age:18 Years",No,200
NCT04373135,Recruiting,"May 8, 2020",December 2020,"Covid-19,Critical Illness,Attitude of Health Personnel,Attitude to Health,Health Behavior,Health Care Utilization","Randomized,Parallel Assignment,Pre-/post-intervention survey with random allocation of a brief educational intervention about scarce resource allocation policy,Health Services Research,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04445246,Recruiting,"May 23, 2020","May 31, 2021","COVID-19,ARDS, Human,Hypoxemic Respiratory Failure","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04376476,Recruiting,"May 5, 2020","June 5, 2021","Infection, Coronavirus,Severe Acute Respiratory Syndrome Coronavirus 2","Non-Randomized,Parallel Assignment,Other,None (Open Label)","gender:All,Min Age:N/A,Max Age:70 Years",No,450
NCT04374539,Recruiting,"April 29, 2020","August 29, 2021",Coronavirus,"Randomized,Parallel Assignment,Multicenter open label randomized controlled clinical trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,116
NCT04438993,Recruiting,"May 29, 2020",November 2020,"COVID,Coronavirus","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04412473,Recruiting,"April 30, 2020",June 2020,Sars-CoV2,"Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04427267,Completed,"June 3, 2020","June 27, 2020",Thermal Condition of Health Workers Who Use Personal Protective Equipment From Biological Hazards During Their Work With COVID-19 Patients,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:45 Years",No,6
NCT04453280,Completed,"May 18, 2020","June 3, 2020","COVID,SARS-CoV-2","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:8 Years,Max Age:N/A",No,695
NCT04566965,Recruiting,"August 18, 2020","December 31, 2023","Covid19,Coronavirus,SARS-CoV Infection","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,230
NCT04333472,Not yet recruiting,"October 6, 2020","July 6, 2021","COVID-19,Coronavirus Infection","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04527471,Recruiting,"August 28, 2020",March 2021,"Coronavirus Infection,Covid-19,SARS-CoV-2","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:80 Years",No,45
NCT04358835,Withdrawn,"September 1, 2020","December 31, 2021",COVID-19,"N/A,Single Group Assignment,This is a single-center, open-label, clinical trial designed to determine whether a ketogenic diet improves gas exchange and reduces ventilator requirements in patients with coronavirus disease intubated for respiratory failure. The study team will prospectively enroll 15 intubated patients with COVID-19 infection and administer a 4:1 ratio enteral ketogenic formula within 48 hours of intubation. This study will compare outcomes to a retrospective cohort of intubated patients with COVID-19 who did not receive ketogenic diet. As other clinical trials begin, co-administration of other therapies as well as standard care treatments will be recorded. In addition, the study will compare clinical outcomes with patients receiving exclusively standard clinical care.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,0
NCT04397172,Recruiting,"April 9, 2020",December 2021,"COVID,Corona Virus Infection,Sars-CoV2","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,50
NCT04312100,Recruiting,"February 1, 2020",February 2021,Coronavirus Disease-2019,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:75 Years",No,30
NCT04490837,"Active, not recruiting","June 22, 2020","September 30, 2020",Covid-19,"Case-Control,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,3500
NCT04336332,Recruiting,"April 1, 2020","April 30, 2021","SARS-CoV-2,COVID-19","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,160
NCT04455451,Enrolling by invitation,"August 6, 2020",December 2021,"COVID,ARDS","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04374097,Completed,"March 31, 2020","April 7, 2020","Post Traumatic Stress Disorder,Anxiety,Depression","Other,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1778
NCT04406545,Recruiting,"May 15, 2020",November 2020,"Coronavirus Infection,Endothelial Dysfunction,Microvascular Rarefaction","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,25
NCT04347928,Recruiting,"April 20, 2020",September 2020,"COVID-19,ARDS,Sars-CoV2","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,15
NCT04433026,Not yet recruiting,August 2020,"September 1, 2021",COVID-19,"Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,90
NCT04397900,Recruiting,"April 9, 2020",July 2020,"Identify the Viral Epitopes of Memory CD8 T Cells From Individuals That Have Recovered From SARS-CoV-2 Infection,Determine Which SARS-CoV-2 Proteins Are Frequently Recognized by T Cells in Patients With Varying HLA Types","Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,80
NCT04469634,Not yet recruiting,"July 31, 2020",July 2021,"SARS-CoV2,COVID-19","N/A,Single Group Assignment,Basic Science,None (Open Label)","gender:All,Min Age:18 Years,Max Age:99 Years",No,150
NCT04477668,Not yet recruiting,October 2020,January 2022,"COVID-19,Acute Hypoxemic Respiratory Failure","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:14 Years,Max Age:N/A",No,320
NCT04343976,Enrolling by invitation,"June 22, 2020","August 31, 2021","COVID-19,COVID","Randomized,Parallel Assignment,Treatment,Single (Participant),Single blind","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04288102,Completed,"March 5, 2020","July 9, 2020",Corona Virus Disease 2019(COVID-19),"Randomized,Parallel Assignment,Randomized, double-blind, placebo-controlled study,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:75 Years",No,100
NCT04393155,Recruiting,"April 16, 2020","May 31, 2023","COVID-19,Acute Respiratory Failure","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,225
NCT04404218,Recruiting,"August 4, 2020",May 2021,COVID,"Randomized,Parallel Assignment,Prospective, double-blinded, placebo-controlled, randomized, multicentre clinical trial,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double blinding, using placebo pills.","gender:All,Min Age:40 Years,Max Age:N/A",No,480
NCT04431297,Not yet recruiting,"September 1, 2020",June 2021,Chronic Stress,"N/A,Single Group Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:65 Years",No,30
NCT04338828,Recruiting,"April 18, 2020",April 2022,COVID19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,260
NCT04276987,Completed,"February 15, 2020","July 31, 2020",Coronavirus,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,24
NCT04410354,Recruiting,"June 16, 2020",December 2020,COVID-19,"Randomized,Parallel Assignment,Eligible study subjects will be randomized 1:1 to receive oral administration of study drug or placebo. Both treatment arms will also receive remdesivir.,Treatment,Triple (Participant, Care Provider, Investigator),Pharmacy prepares medications that are coded","gender:All,Min Age:18 Years,Max Age:N/A",N/A,80
NCT04363450,Recruiting,"April 27, 2020","June 1, 2021","COVID-19,Corona Virus Infection,Wuhan Coronavirus,Prophylaxis,Healthcare Worker,Sars-CoV2,Hydroxychloroquine","Randomized,Parallel Assignment,Randomized, placebo-controlled, double-blind study with 1:1 randomization of hydroxychloroquine to placebo,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Participants will be randomized to the investigational drug (hydroxychloroquine) or placebo. Both will have identical appearance and will be taken at the same dosing interval. The administration of the drug and assessment will be blinded. After final analysis, study arms will be unmasked.","gender:All,Min Age:18 Years,Max Age:N/A",No,1700
NCT04414410,Enrolling by invitation,"May 12, 2020","September 30, 2020","COVID,Sars-CoV2","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1500
NCT04280224,Recruiting,"February 15, 2020","December 30, 2020",Novel Coronavirus Pneumonia,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:65 Years",No,30
NCT04386044,Not yet recruiting,"June 1, 2020","June 1, 2021","COVID-19,Vitamin D Deficiency","Other,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04344236,Recruiting,"April 9, 2020","May 9, 2020",COVID-19,"Randomized,Parallel Assignment,Randomized controlled open label trial, parallel design,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:79 Years",No,48
NCT04530136,Not yet recruiting,"September 15, 2020","March 31, 2021",Confirmed Coronavirus Disease,"Randomized,Parallel Assignment,Treatment,Single (Investigator)","gender:All,Min Age:18 Years,Max Age:85 Years",N/A,120
NCT04424017,Recruiting,"June 7, 2020","September 30, 2020","COVID,Corona Virus Infection","Other,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:60 Years",No,726
NCT04525742,Recruiting,"July 5, 2020","September 15, 2020","COVID-19,Disabilities Multiple,Cerebral Palsy,Muscular Dystrophies","N/A,Single Group Assignment,One study group will be researched- only disabled children's parents, in one arm -way,Screening,None (Open Label),No masking will be done","gender:All,Min Age:18 Years,Max Age:65 Years",No,190
NCT04374565,"Active, not recruiting","May 5, 2020","April 5, 2021","Corona Virus Infection,SARS-CoV 2,SARS Pneumonia,Pneumonia","N/A,Single Group Assignment,This is a single arm phase II trial to assess preliminary efficacy and confirm safety of infusions of antiSARS-CoV-2 convalescent plasma in hospitalized patients with acute respiratory symptoms with or without confirmed interstitial COVID-19 pneumonia by CXR or chest CT. A total of 29 eligible subjects will be enrolled to receive high titer anti-SARS-CoV-2 plasma. Participants will be compared to a historical control group via retrospective chart review.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,29
NCT04570254,"Active, not recruiting","August 19, 2020","November 15, 2020","Pneumonia, Viral,Covid19,ARDS,Oxidative Stress","Non-Randomized,Parallel Assignment,septic shock and without septic shock will be divided into two groups. An antioxidant will be administered orally or by orogastric tube (vitamin C, melatonin, n-acetylcysteine, vitamin E) plus pentoxifylline. Following a decision tree that the treating physician will follow.,Treatment,Triple (Participant, Investigator, Outcomes Assessor),They will be blinded to the patient's treatment, the patient or participant, the investigator, and the outcome assessor. You will only receive the participant number during the analysis. The care provider will not be blinded; they will know which antioxidant plus pentoxifylline the patient will receive; however, they will not have access to the results until the clinical trial is concluded.","gender:All,Min Age:N/A,Max Age:N/A",No,11
NCT04353206,Recruiting,"June 27, 2020",May 2021,"Covid-19,Sars-CoV2","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04340466,Recruiting,"April 3, 2020","April 30, 2021","Pneumonia, Viral,Critically Ill,Corona Virus Infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,220
NCT04353609,Recruiting,"April 18, 2020",December 2020,"Sars-CoV2,Chronic Inflammatory Rheumatism,Autoimmune Diseases","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,13770
NCT04344015,Recruiting,"April 13, 2020","April 12, 2021",COVID-19,"N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04371367,Recruiting,"April 27, 2020","October 27, 2020",COVID,"Randomized,Parallel Assignment,Parallel Assignment,Treatment,Double (Participant, Investigator),Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:80 Years",No,108
NCT04432961,Not yet recruiting,July 2020,July 2021,COVID-19,"Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,200
NCT04548895,Not yet recruiting,September 2020,"February 26, 2021","Covid19,Community-Acquired Respiratory Tract Infection","Ecologic or Community,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,30
NCT04565665,Recruiting,"July 29, 2020","April 30, 2021","COVID-19 Infection,COVID-19-Associated Acute Respiratory Distress Syndrome","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,70
NCT04337983,Recruiting,"March 13, 2020",April 2021,"Coronavirus,SARS-CoV-2,COVID-19,Acute Respiratory Distress Syndrome,Shock,Acute Circulatory Failure,Left Ventricular Dysfunction,Fluid Overload","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,200
NCT04502433,Not yet recruiting,"September 1, 2020","November 30, 2020",Acute Respiratory Distress Syndrome,"Randomized,Parallel Assignment,Seventy patients will be randomized in the study with a ratio 3:2 (i.e. 42 patients in the poractant alfa arm and 28 in the control arm). An additional exploratory cohort of 15 patients in ECMO will be randomized by 3 sites with a ratio 3:2 (i.e. 9 patients in the poractant alfa arm and 6 in the control arm).,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,85
NCT04356378,Recruiting,"June 2, 2020","March 2, 2022",Infection With Coronavirus SARS-CoV2,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04350450,Withdrawn,April 2020,August 2020,"COVID,Coronavirus,COVID-19","Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:99 Years",No,0
NCT04365816,Completed,"April 30, 2020","July 10, 2020",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,403
NCT04358536,Completed,"April 1, 2020","April 17, 2020",COVID-19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,230
NCT04472793,Recruiting,"May 11, 2020",December 2023,COVID-19,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04542447,Recruiting,"September 1, 2020","September 30, 2020",Covid19,"Randomized,Single Group Assignment,Immunomodulator in COVID 19, Intervention - Sequentially numbered IP kits,Treatment,None (Open Label),An open label proof of concept study","gender:All,Min Age:18 Years,Max Age:65 Years",No,10
NCT04423978,Completed,"May 4, 2020","June 15, 2020",COVID-19,"Ecologic or Community,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1826
NCT04500132,Recruiting,"May 28, 2020",May 2022,COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:19 Years,Max Age:N/A",No,60
NCT04384419,Recruiting,"May 29, 2020","June 1, 2021","Mental Disorder,General Population","Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04433260,Recruiting,"July 25, 2020",September 2021,Mental Health,"Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1050
NCT04441632,Completed,"June 15, 2020","July 30, 2020","Burnout,Stress, Emotional","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,24
NCT04412252,Withdrawn,"July 6, 2020","October 18, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:99 Years",No,0
NCT04393805,Recruiting,"June 1, 2020",December 2020,"COVID-19,Hypercoagulability","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,877
NCT04363437,Recruiting,"April 26, 2020","June 14, 2020",Coronavirus Infection,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:100 Years",No,70
NCT04459351,Recruiting,"June 19, 2020",June 2023,"Coronavirus,Corona Virus Infection,COVID-19,2019nCoV,2019 Novel Coronavirus Infection","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04379297,"Active, not recruiting","April 10, 2020","December 31, 2021",COVID19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1800
NCT04492865,Not yet recruiting,"July 30, 2020","October 30, 2020",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04560608,Completed,"March 15, 2020","July 31, 2020",Covid19,"Cohort,Other","sampling_method:Probability Sample,gender:All,Min Age:70 Years,Max Age:N/A",No,255
NCT04356417,Not yet recruiting,April 2020,June 2020,"AMD, ACEi's/ARB Prevent/Worsen Risk of COVID-19 Infection","Cohort,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,6000000
NCT04365101,Recruiting,"May 13, 2020","June 30, 2021","Coronavirus,Coronavirus Infection,Severe Acute Respiratory Syndrome Coronavirus 2,Pneumonia,Pneumonia, Viral,Lung Diseases,Respiratory Tract Disease,Respiratory Tract Infections,Coronaviridae Infections,Nidovirales Infections,RNA Virus Infections,Virus Disease,Immunologic Disease,ARDS,Immunologic Factors,Physiological Effects of Drugs,Antiviral Agents,Anti-infective Agents,Analgesics,Antimetabolites, Antineoplastic","Randomized,Sequential Assignment,Phase I will evaluate the safety and efficacy of multiple doses of CYNK-001 (Days 1,4, and 7) in 14 patients.
Phase II will utilize a randomized, open-label design; multiple doses of CYNK-001 will be compared to the control group: Best Supportive Care. Up to 72 patients will be included in the Phase II portion of the study with a 1:1 randomization ratio.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,86
NCT04438837,Not yet recruiting,July 2020,June 2022,"Coronavirus Disease 2019 (COVID-19),Post-Exposure Prophylaxis","Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,582
NCT04395976,Not yet recruiting,"June 10, 2020","October 1, 2020",Covid-19,"Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04393792,Recruiting,May 2020,August 2020,Coronavirus Infection,"Randomized,Parallel Assignment,unblinded parallel group design with 1:1 randomised allocation to treatment or control,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04352959,Recruiting,"April 27, 2020","December 20, 2020","COVID19,Mouthwash,Saliva","Randomized,Parallel Assignment,Prevention,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:70 Years",No,206
NCT04384705,Recruiting,"June 17, 2020",July 2021,SARS-CoV Infection,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04520620,Withdrawn,"May 2, 2020","July 10, 2020",Sars-CoV2,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04285801,Completed,"February 14, 2020","February 25, 2020",COVID-19,"Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,8
NCT04373733,Recruiting,"May 1, 2020","March 31, 2021",Coronavirus Infection,"Randomized,Parallel Assignment,Open-label parallel group randomised control trial. One trial treatment arm and one standard of care comparator arm.,Treatment,None (Open Label),Open label","gender:All,Min Age:18 Years,Max Age:N/A",No,450
NCT04567927,Completed,"March 3, 2020","May 28, 2020",SARS Virus,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04369742,Suspended,"April 15, 2020",June 2021,COVID-19,"Randomized,Parallel Assignment,Placebo-controlled, Randomized,Treatment,Double (Participant, Care Provider),Double-blind","gender:All,Min Age:18 Years,Max Age:N/A",No,626
NCT04488484,"Active, not recruiting","July 1, 2020","December 31, 2021",COVID-19,"N/A,Single Group Assignment,The research is a prospective, follow-up cohort, non-randomized and interventional study that aims at following patients who presented a positive serology for the COVID-19,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,450
NCT04479345,Not yet recruiting,July 2020,September 2020,"Knowledge, Attitudes, Practice","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:25 Years,Max Age:N/A",No,100
NCT04341116,Recruiting,"April 11, 2020",September 2020,Coronavirus Disease 2019 COVID-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,144
NCT04344730,Recruiting,"April 10, 2020","December 31, 2020","Acute Hypoxemic Respiratory Failure,COVID-19","Randomized,Factorial Assignment,In non-mechanically ventilated patients, a 2x2 factorial design will be used to assess the two interventions, separately.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),The masking label is available only for the treatment assignation","gender:All,Min Age:18 Years,Max Age:N/A",No,550
NCT04358926,Recruiting,"April 30, 2020","July 30, 2020","COVID-19,Desaturation of Blood","Randomized,Parallel Assignment,Randomized controled, double blinded study,Treatment,Double (Participant, Outcomes Assessor),The participants will be be able to tell if treated by hyperbaric or normobaric oxygen being in the chamber, blinded to the measured pressure.
The outcome assessors will receive anonymous blinded data.","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04378777,Enrolling by invitation,"May 1, 2020",December 2021,"Coronavirus Disease 2019 (COVID-19),SARS-CoV-2","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04348370,Recruiting,"April 20, 2020",November 2021,"Coronavirus,Coronavirus Infection,Coronavirus as the Cause of Diseases Classified Elsewhere","Randomized,Parallel Assignment,Participants will be randomized to BCG:placebo in a 1:1 ratio.,Prevention,Double (Participant, Investigator),Randomization will be done centrally and computer generated with stratification per hospital in random blocks of 2, 4 and 6. The BCG vaccine will be administered by research nurses. Participants and investigators will be blinded. The research nurse that administers the BCG vaccine or placebo will not be blinded. This research nurse will not be involved in the collection of outcome data.","gender:All,Min Age:18 Years,Max Age:75 Years",No,1800
NCT04553705,Recruiting,"September 20, 2020","December 4, 2020","Covid19,Immunodeficiency","Randomized,Sequential Assignment,Treatment,Double (Participant, Care Provider)","gender:All,Min Age:25 Years,Max Age:40 Years",No,200
NCT04396106,Recruiting,"May 26, 2020",January 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator),Blinded","gender:All,Min Age:45 Years,Max Age:80 Years",No,190
NCT04540484,Recruiting,"August 26, 2020","September 24, 2021","Covid19,SARS-CoV Infection,Communicable Disease","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,900
NCT04375761,"Active, not recruiting","May 1, 2020",December 2020,"Coronavirus Disease 2019 (COVID-19),SARS-CoV-2","Family-Based,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,5605
NCT04380701,Recruiting,"April 23, 2020",November 2020,"Infections, Respiratory,Virus Diseases,Infection Viral,Vaccine Adverse Reaction,RNA Virus Infections","Non-Randomized,Sequential Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:85 Years",No,456
NCT04547114,Recruiting,"September 14, 2020","April 30, 2021",SARS-CoV-2 Infection,"Case-Control,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04527315,Recruiting,"July 17, 2020",August 2023,Covid19,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,350
NCT04368845,Recruiting,"May 11, 2020",March 2021,"COVID-19,Comorbidities and Coexisting Conditions","Randomized,Parallel Assignment,Two arm single blinded randomized control trial,Treatment,Single (Outcomes Assessor),Block Randomisation, Initial and final outcome assessors blinded to treatment arm","gender:All,Min Age:20 Years,Max Age:65 Years",No,100
NCT04405726,Recruiting,"March 27, 2020",March 2022,SARS-CoV-2,"Case-Only,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:1 Year,Max Age:N/A",No,500
NCT04493359,Recruiting,"July 25, 2020","February 14, 2022","Covid19,Angiotensin II Receptor Antagonist Adverse Reaction","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,240
NCT04380662,Not yet recruiting,"June 30, 2020","December 30, 2020",Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,800
NCT04293692,Withdrawn,"February 24, 2020","February 25, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:75 Years",No,0
NCT04449588,Recruiting,"July 23, 2020","August 7, 2022",COVID-19 Pneumonia,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,368
NCT04477993,Recruiting,"July 17, 2020","December 31, 2021","Severe Acute Respiratory Syndrome Coronavirus 2,SARS-CoV2","Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:95 Years",No,200
NCT04383548,Not yet recruiting,"June 1, 2020","January 1, 2021",COVID19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:21 Years,Max Age:50 Years",No,100
NCT04446286,Recruiting,"June 18, 2020","August 18, 2020",Covid-19,"Case-Only,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04563650,Recruiting,"September 18, 2020",November 2021,"Covid19,Geriatric Medicine,Seroconversion,Immunosenescence","Randomized,Parallel Assignment,Screening,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,330
NCT04403672,Recruiting,"May 18, 2020","July 24, 2020",High Sensitivity and Specificity (With 95% Confidence Interval) of RealDetect™ COVID-19 RT-PCR Kit,"Case-Control,Prospective","sampling_method:Probability Sample,gender:All,Min Age:5 Years,Max Age:65 Years",No,120
NCT04421534,Not yet recruiting,June 2020,November 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:65 Years",No,150
NCT04401475,Not yet recruiting,September 2020,April 2021,"COVID-19,ARDS","Randomized,Sequential Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,865
NCT04409522,Recruiting,"May 12, 2020","September 25, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Investigator, Outcomes Assessor)","gender:All,Min Age:16 Years,Max Age:100 Years",No,55
NCT04329832,"Active, not recruiting","March 30, 2020","December 31, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,85
NCT04445597,Recruiting,"May 7, 2020","June 30, 2020",SARS-CoV 2,"N/A,Single Group Assignment,Basic Science,None (Open Label)","gender:All,Min Age:N/A,Max Age:70 Years",No,8
NCT04538469,Not yet recruiting,September 2020,December 2021,"Cardiovascular Diseases,Delirium,Critical Illness,Intensive Care Unit Delirium,Thoracic Diseases,Respiratory Failure,Cardiac Disease,Cardiac Failure","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,1000
NCT04487119,Completed,"August 12, 2020","August 23, 2020",Covid19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:18 Years",No,29
NCT04371562,Completed,"March 1, 2020","April 15, 2020",COVID,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04463706,Recruiting,"June 1, 2020","December 31, 2021",Covid19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,20000
NCT04480424,Recruiting,"September 17, 2020",February 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04497649,Recruiting,"July 1, 2020","October 10, 2020",Covid19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04460677,Recruiting,"August 12, 2020","March 31, 2021","Psychological Distress,Stress, Psychological,Autism Spectrum Disorder","Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04473352,Not yet recruiting,September 2020,November 2021,Covid19,"Other,Prospective","sampling_method:Non-Probability Sample,gender:Male,Min Age:18 Years,Max Age:N/A",No,80
NCT04403061,Recruiting,"May 22, 2020","September 30, 2020","Disease, Viral,Cytokine Release Syndrome,TLRs","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,80
NCT04366180,Recruiting,"April 24, 2020",October 2020,Covid-19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:20 Years,Max Age:N/A",No,314
NCT04435314,Not yet recruiting,June 2020,August 2020,covid19,"Randomized,Parallel Assignment,Subjects will be randomized to receive either nitazoxanide (n=100) or placebo (n=100),Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04383678,Recruiting,"March 1, 2020","December 31, 2020","COVID-19,Extracorporeal Membrane Oxygenation Complication,Acute Respiratory Distress Syndrome","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,200
NCT04466280,Recruiting,"July 15, 2020","December 15, 2020",COVID-19,"Randomized,Parallel Assignment,Prevention,Double (Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,180
NCT04391686,Recruiting,"July 3, 2020","March 2, 2021","COVID-19,Obesity","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,90
NCT04386395,"Active, not recruiting","March 30, 2020","May 30, 2020","SARS-CoV-2,Immune System Disorder","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,15
NCT04389294,Recruiting,"May 5, 2020","October 30, 2020",COVID,"N/A,Single Group Assignment,Health Services Research,None (Open Label)","gender:All,Min Age:21 Years,Max Age:N/A",No,300
NCT04419545,Recruiting,"March 24, 2020","March 31, 2021","Radiology,Artificial Intelligence","Case-Control,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,2500
NCT04408157,"Active, not recruiting","May 20, 2020","June 22, 2021",COVID,"Randomized,Parallel Assignment,Two-arm parallel randomised-controlled trial with nested qualitative study,Treatment,None (Open Label),Blinding not possible as passive control arm and using self-report outcomes.","gender:All,Min Age:18 Years,Max Age:N/A",No,165
NCT04487873,Not yet recruiting,"July 23, 2020","December 1, 2020","Covid19,Bronchiectasis","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:60 Years",No,28
NCT04365517,Not yet recruiting,"July 29, 2020","December 30, 2020","Covid19,Diabetes Mellitus, Type 2,CKD","Randomized,Parallel Assignment,A randomized controlled open label intervention study is proposed. Patients hospitalized for COVID-19 and suffering from type 2 diabetes will be included in the study and divided into two groups by randomization: sitagliptin add-on therapy with nutritional therapy with or without insulin (study group) vs nutritional therapy with or without insulin (group of control, standard therapy),Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,170
NCT04360824,Recruiting,"May 6, 2020","April 16, 2021",COVID 19 Associated Coagulopathy,"Randomized,Parallel Assignment,This is a multi-center, randomized, open-label study comparing standard prophylactic dose enoxaparin (40 mg SC daily or 30 or 40 mg SC twice daily if BMI ≥30kg/m2; standard of care arm) versus intermediate-dose enoxaparin (1 mg/kg SC daily or 0.5 mg/kg SC twice daily if BMI≥30kg/m2; intervention arm) in hospitalized patients with laboratory-confirmed SARS-CoV-2 infection.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:100 Years",No,170
NCT04388579,Completed,"March 20, 2020","March 27, 2020",Respiratory Disease,"Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:88 Years",No,100
NCT04337502,Completed,"December 23, 2019","March 3, 2020","Coronavirus,Machine Learning","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,300
NCT04510441,Recruiting,"May 26, 2020","May 1, 2022",Coronavirus,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04361214,Recruiting,"May 5, 2020",September 2020,COVID-19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04335305,Recruiting,"April 9, 2020","June 30, 2021","COVID-19,Pneumonia, Viral","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,24
NCT04521088,Recruiting,"July 2, 2020","December 31, 2020",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1000
NCT04373798,Recruiting,"May 4, 2020","November 30, 2020",Coronavirus Infection,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,3000
NCT04422470,Recruiting,"June 22, 2020","July 22, 2021",Coronavirus Infection and Hematologic Diseases,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04370249,Recruiting,"April 9, 2020",June 2020,"Acute Respiratory Distress Syndrome,COVID-19","Case-Only,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04315948,Recruiting,"March 22, 2020",March 2023,Corona Virus Infection,"Randomized,Parallel Assignment,From March 22, 2020 to May 24, 2020, the study randomized participants 1:1:1:1:1 to standard of care alone (control) or with investigational product added.
From May 24, 2020 to June 29, 2020, the study randomized participants 1:1:1:1 to standard of care alone (control) or with investigational product added.
Since June 29, 2020, the study will randomize participants 1:1 to standard of care alone (control) or with investigational product added.
If additional arms are added to or dropped from the trial, randomization will proceed with an equal probability of assignment to each of the remaining arms.,Treatment,None (Open Label),the treatment arm SOC + hydroxychloroquine has been ceased since May 24, 2020;
the treatment arm SOC + lopinavir / Ritonavir and lopinavir / ritonavir + interferon ß-1a has been ceased since June 29, 2020","gender:All,Min Age:18 Years,Max Age:N/A",No,3100
NCT04517396,Enrolling by invitation,"August 18, 2020","August 31, 2021",Covid19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04457570,Recruiting,"June 15, 2020","February 15, 2021","COVID, Cancer","Case-Control,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,600
NCT04374617,Completed,"April 1, 2020","May 1, 2020","COVID-19,Critical Illness,Venous Thromboembolism,Venous Thromboses,Venous Thromboses, Deep,Venous Thrombosis Pulmonary,Pulmonary Embolism,Pulmonary Embolism and Thrombosis,Sars-CoV2,SARS-CoV Infection","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,230
NCT04449965,Not yet recruiting,"July 1, 2020","December 1, 2020",Covid19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator),The investigator will be blinded to whether or not the patients are receiving either active treatments or placebo, and assignments will be concealed throughout the study. The patients will know if they are in the nasal gel spray or rinse group but will be blinded to whether or not they are receiving the active treatment or placebo if they are randomized into the rinse group.","gender:All,Min Age:19 Years,Max Age:N/A",No,81
NCT04358549,"Active, not recruiting","April 17, 2020","November 1, 2020",COVID-19,"Randomized,Parallel Assignment,Open-label, randomized (1:1 ratio) to receive favipiravir plus standard of care or standard of care alone.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",N/A,50
NCT04574050,Not yet recruiting,"December 3, 2020","June 30, 2022","Cancer,COPD,Asthma,Bronchiectasis Adult,Interstitial Lung Disease,Cystic Fibrosis,Chronic Heart Failure,Sickle Cell Disease,Renal Failure,Liver Failure,Post COVID-19,Dyspnea","Randomized,Parallel Assignment,A feasibility RCT comprising two groups:
Intervention (SELF-BREATHE in addition to standard NHS care)
Control group (standard / currently available NHS care),Treatment,Single (Outcomes Assessor),Single blind","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04457726,Recruiting,"July 1, 2020",December 2022,COVID-19,"Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:1 Year,Max Age:90 Years",No,18
NCT04322682,Recruiting,"March 23, 2020",December 2020,Corona Virus Infection,"Randomized,Parallel Assignment,This will be a randomized, double-blind, placebo-controlled, multi-center study. Following signature of the informed consent form, approximately 6000 subjects meeting all inclusion and no exclusion criteria will be randomized to receive either colchicine or placebo (1:1 allocation ratio) for 30 days. Follow-up phone or video assessments will occur at 15 and 30 days following randomization for evaluation of the occurrence of any trial endpoints or other adverse events.,Treatment,Single (Participant)","gender:All,Min Age:40 Years,Max Age:N/A",No,6000
NCT04402983,Recruiting,"May 27, 2020","December 1, 2020","Covid19,Telerehabilitation,Physical Therapy","Randomized,Parallel Assignment,Randomized controlled clinical trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,34
NCT04460274,Completed,"December 31, 2019","June 20, 2020",Covid-19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,7882471
NCT04400682,Completed,"May 28, 2020","June 18, 2020",Bioequivalence,"Randomized,Crossover Assignment,Other,None (Open Label)","gender:Male,Min Age:20 Years,Max Age:40 Years",No,30
NCT04332666,Not yet recruiting,"September 30, 2020","June 15, 2021","Coronavirus,Respiratory Failure,Coronavirus Sars-Associated as Cause of Disease Classified Elsewhere,SARS-CoV-2","Randomized,Parallel Assignment,Randomized, controlled, investigator initiated, phase II/phase III seamless, adaptive, single blinded, interventional trial to evaluate the efficacy, safety and clinical impact of intravenous Ang-(1-7) infusion compared to standard treatment in ICU patients with severe respiratory failure associated with COVID-19. This study will be conducted initially in one center (Erasme Hospital, Belgium), but other sites will be allowed to join if: Number of expected patients with COVID related ARF ≥ 10, experience in treatment of ARDS patients (> 25/year), including prone positioning ,availability of the equipment required to provide the blood sample processing and storage. We planned a first phase of the study where 30 patients will be randomly receiving Ang-(1-7) or placebo to confirm the safety. The Final power calculation will be reassessed after 30 included patients (i.e. 15 in each arm), in line with a preplanned expected total number of patients needed of 60.,Treatment,Triple (Participant, Investigator, Outcomes Assessor),Randomization will be performed using sealed envelopes with a ratio of 1:1 including information on treatment assignment and a five-digit number, which will be open by the person responsible for drug constitution. Each vial or syringe will be then labeled with the randomly allocated number it will be assigned to the nursing personnel. The doctors and nurses administering the drugs, as well as the local investigators and research personnel who collected data, were unaware of the treatment assignments.","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04362969,Not yet recruiting,May 2020,May 2020,COVID,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04490200,Not yet recruiting,"November 30, 2020","July 31, 2021","Covid19,SARS-CoV Infection,Worker-Patient Transmission, Healthcare","Randomized,Parallel Assignment,This is a randomized controlled clinical trial, characterized by the application of semi facial respirators, in which participants will be randomly and concealed allocated into two groups: VESTA respirator (GExp) and Conventional N95 respirator (CG). The participants will be healthcare professionals working in hospital environments contaminated by SARS-Cov-2. The study will be reported following the recommendations of the CONSORT Statement.,Prevention,Triple (Participant, Care Provider, Outcomes Assessor),The outcome assessor won't have any knowledge about the study purposes and will be unaware of the group allocation.
Participants will be blinded as they will not distinguish the novel respirator (VESTA) from the conventional N95 respirator (both will have the same shape, color and size).
The statistical analysis will also be performed blinded for group allocation.","gender:All,Min Age:20 Years,Max Age:59 Years",No,1000
NCT04471831,Not yet recruiting,"July 13, 2020","December 31, 2021","Corona Virus Infection,Stroke","Non-Randomized,Parallel Assignment,This clinical controlled study will involve a minimum of 30 stroke survivors who is positive for coronavirus (CoViD-19) admitted into different isolation centres in Nigeria,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),The identification and selection of participants will be done by none of investigators. Allocation into group will also be done by none of the investigators. Outcome assessment will be done by none of the investigators. Participants will not be privy to another group","gender:All,Min Age:18 Years,Max Age:120 Years",No,30
NCT04388527,Recruiting,"April 30, 2020","March 31, 2021",Covid-19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04350736,Completed,"April 23, 2020","June 24, 2020","Acute Lung Injury (ALI) Associated With COVID-19,Inflammatory Lung Conditions Associated With COVID-19","Randomized,Sequential Assignment,double-blind, randomized, placebo-controlled,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:50 Years",No,54
NCT04340557,Recruiting,"March 27, 2020","December 31, 2020",SARS-CoV Infection,"Randomized,Parallel Assignment,Subjects will be randomized into one of two groups: Standard of Care or Standard of Care plus an ARB.,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04433325,Not yet recruiting,June 2020,September 2020,"COVID-19,Intensive Care Unit Syndrome","Case-Control,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04466241,Not yet recruiting,"September 10, 2020","December 20, 2020","COVID-19,COVID-19 Drug Treatment,Severe Acute Respiratory Syndrome Coronavirus 2","Randomized,Parallel Assignment,Phase IIb, comparative, multicenter, randomized, superiority, parallel-group, open-label clinical trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,294
NCT04409847,Recruiting,"June 1, 2020","May 31, 2021","COVID,Hypertension","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:30 Years,Max Age:60 Years",No,70
NCT04384497,Recruiting,"May 7, 2020",December 2020,COVID-19,"N/A,Single Group Assignment,An open, non-randomised controlled, safety and dose identifying clinical trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04394195,Recruiting,"March 25, 2020","September 1, 2020",CORONAVIRUS INFECTIONS,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04357769,Recruiting,"April 10, 2020","April 25, 2020","Psychological Distress,COVID,Severe Mental Disorder","Case-Control,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:70 Years",No,400
NCT04308317,Enrolling by invitation,"March 5, 2020","May 1, 2021","Corona Virus Disease 2019,COVID-19","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,60
NCT04275388,Not yet recruiting,"May 15, 2020","December 14, 2021",2019 Novel Coronavirus Pneumonia,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:100 Years",No,426
NCT04530435,Not yet recruiting,"September 1, 2020","April 30, 2021","COVID-19,SARS-CoV-2","Randomized,Parallel Assignment,This study is designed as a randomised, controlled, open-label trial with two parallel groups and a primary endpoint of CAT-score after 30 days of intervention.
Randomization lists will be computer-generated using an appropriate statistical software and based upon permuted random blocks. The allocation ratio will be 1:1 stratified for the following baseline conditions:
Sex
Age (≥60 and <60 years),Prevention,Single (Outcomes Assessor),Outcome assessors will be blinded to treatment allocation where possible. This is of outmost importance, and participants are requested not to disclose their allocation when outcomes are assessed. To test the blinding efficacy, the outcome assessors are asked what treatment strategy they think a patient has received after assessments.","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04395482,Recruiting,"April 15, 2020","October 15, 2020",covid19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04401293,Recruiting,"April 26, 2020","April 26, 2021","Sars-CoV2,COVID","Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator),Due to the pragmatic nature of this study ""open-label multi-center randomized active control trial"" with pseudo-blinding mechanisms at the time of randomization the study subject and corresponding Site PIs will be blinded (unaware of specific treatment arm the patient is assigned to i.e. Arm 0 or Arm 1). The study pharmacists as well as data extractors and designated randomization personnel (i.e. research coordinators and/or research nurses performing the randomization process) will be un-blinded (aware of specific treatment arm the patient is assigned to i.e. Arm 0 or Arm 1). At the time of subject randomization study subjects will be stratified to either ICU level of care vs. Non-ICU level of care.","gender:All,Min Age:18 Years,Max Age:N/A",No,308
NCT04463849,Recruiting,"June 30, 2020","June 30, 2021","COVID19,BETA-CELL FUNCTION","Non-Randomized,Parallel Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,24
NCT04482647,Recruiting,"June 17, 2020","July 1, 2021",COVID-19 Infection,"N/A,Single Group Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:N/A,Max Age:70 Years",No,50
NCT04390139,Recruiting,"May 13, 2020",December 2020,"COVID-19,SARS-CoV 2,Adult Respiratory Distress Syndrome","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:75 Years",No,30
NCT04349371,Recruiting,April 2020,April 2021,COVID,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,350
NCT04528901,Recruiting,September 2020,December 2022,Covid-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1080
NCT04390217,Not yet recruiting,"October 31, 2020","March 31, 2021","COVID-19,Coronavirus Disease 2019,Covid19,COVID-19 Pneumonia","Randomized,Parallel Assignment,All patients will be randomized into one of two treatment groups (LB1148 or Placebo) in a 1:1 ratio, and stratified by peripheral capillary oxygen saturation and by PF ratio at the time of Screening.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Quadruple blinding including the sponsor and all sponsor agents, subjects, investigators, care providers, and family members.","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04374422,Completed,"April 10, 2020","April 12, 2020","Sexual Behavior,COVID","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:N/A",No,58
NCT04468386,"Active, not recruiting","July 7, 2020","September 30, 2020",Focus in on Collecting Paired Specimens for Matrix Equivalency,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:21 Years,Max Age:N/A",No,40
NCT04344548,Not yet recruiting,"April 13, 2020","November 10, 2020",COVID,"N/A,Single Group Assignment,Phase I/II immunotherapy with NK cells for mild infected COVID-19 patients,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,10
NCT04451291,Not yet recruiting,"August 24, 2020","February 24, 2021","COVID-19,Acute Respiratory Distress Syndrome","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,20
NCT04331600,Recruiting,"April 16, 2020","December 31, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04520880,Not yet recruiting,August 2020,February 2021,"Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV 2 Infection),Hospitalized Patients,Laboratory-confirmed SARS-CoV 2 Infection","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,158
NCT04344431,Recruiting,"April 14, 2020",May 2021,Covid-19,"Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:90 Years",No,100
NCT04513990,Recruiting,"April 9, 2020","April 30, 2021",COVID-19 Infection,"N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,1500
NCT04287686,Withdrawn,February 2020,April 2020,COVID-19,"Randomized,Parallel Assignment,2-arm pilot study,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,0
NCT04327570,Recruiting,"March 27, 2020","September 30, 2020",Coronavirus Infections,"Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04578132,"Active, not recruiting","September 30, 2020",October 2021,"Covid19,Genito Urinary Cancer","Ecologic or Community,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,250
NCT04412486,Recruiting,"June 1, 2020","May 31, 2022",COVID-19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04385017,Recruiting,"May 11, 2020","June 12, 2021",COVID-19 by SARS-CoV-2 Infection,"N/A,Single Group Assignment,Patient with COVID-19 disease,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04357431,Completed,"April 22, 2020","May 30, 2020",COVID,"Other,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,565
NCT04351620,Recruiting,April 2020,June 2020,COVID-19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04474340,Recruiting,"May 21, 2020","December 30, 2020","Moderate COVID-19 Pneumonia, Severe COVID-19 Pneumonia,Pneumonia, Viral","Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:15 Years,Max Age:85 Years",No,300
NCT04385238,Completed,"May 15, 2020","June 20, 2020","COVID-19,Pregnancy Complications,Mental Health Wellness 1,Anxiety,Depression,Ptsd,Coronavirus","Case-Only,Cross-Sectional","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:N/A",No,7000
NCT04312464,Enrolling by invitation,"January 1, 2020","March 18, 2020","COVID-19,Cardiovascular Diseases","Case-Control,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04416048,Not yet recruiting,"August 1, 2020","May 30, 2021",COVID-19,"Randomized,Parallel Assignment,A multicenter, prospective, randomized, event-driven study.,Prevention,None (Open Label),Central randomization will be implemented in this study. Subjects will be randomly assigned to 1 of 2 treatment groups based on a computer-generated randomization schedule prepared before the study under the supervision of the sponsor. The randomization will be stratified by site, gender, age, kidney function (subjects with eGFR ≥30 mL/min/1.73m2 and <50 mL/min/1.73m2 versus subjects with eGFR ≥50 mL/min/1.73m2), history of CAD or heart failure and oxygen demand on admission to the hospital. The computer system will assign a unique treatment code, which will dictate the treatment assignment and study drug kits for the subject. The requestor must use his or her own user identification and personal identification number when contacting the system and will then give the relevant subject details to uniquely identify the subject.","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04365582,Suspended,"May 7, 2020","February 7, 2021",COVID,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:50 Years,Max Age:N/A",No,640
NCT04371640,Recruiting,May 2020,August 2020,"SARS-CoV-2,Covid-19","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:65 Years",No,40
NCT04458363,Recruiting,July 2020,June 2022,COVID,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:N/A,Max Age:22 Years",No,50
NCT04402918,Recruiting,"May 17, 2020","December 31, 2020",Sars-CoV2,"N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:Female,Min Age:18 Years,Max Age:N/A",No,160
NCT04377100,Recruiting,"October 12, 2020","February 28, 2021","Anxiety,Healthy Volunteers","N/A,Single Group Assignment,Basic Science,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,3000
NCT04480632,Not yet recruiting,"August 1, 2020",August 2022,COVID-19,"Non-Randomized,Parallel Assignment,Quasi-experimental and open-label intervention study. In this study, the application of convalescent plasma is considered as an intervention, but randomization will not be performed by investigators; one arm will be patients who received ABO compatible convalescent plasma and the comparison group will be those patients with intervention indication but without compatible ABO plasma units within the institution.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,44
NCT04359836,Recruiting,"April 16, 2020","July 31, 2021","Gut Microbiome,Gastrointestinal Microbiome,COVID,COVID-19,Corona Virus Infection,Coronavirus,Coronaviridae Infections,Coronavirus 19,Coronavirus-19,COVID 19","Other,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,250
NCT04484493,Completed,"August 8, 2020","September 6, 2020","Covid19,Anosmia","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04513158,Recruiting,"August 14, 2020","December 31, 2021",Covid19,"N/A,Single Group Assignment,All hospitalized patients meeting study inclusion/exclusion criteria and providing informed consent for participation in the study will receive one unit (approximately 200 mL) of convalescent plasma over one hour to with data collection of routine physical exams/clinical assessments (daily) and routine lab results (every 3 days).,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:99 Years",N/A,100
NCT04348695,Recruiting,"April 12, 2020","May 13, 2020",Coronavirus Infection,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,94
NCT04344444,"Active, not recruiting","April 13, 2020","December 10, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:100 Years",No,600
NCT04405362,Not yet recruiting,May 2020,May 2021,"SARS-CoV 2,Traumatic Stress Disorder","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,753
NCT04384614,Withdrawn,"May 15, 2020","July 15, 2020","Covid 19,BCG Vaccination","Other,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,0
NCT04390477,Recruiting,"May 4, 2020",May 2021,"COVID-19,Coronavirus Infection","Randomized,Parallel Assignment,Treatment,None (Open Label),Random numbers table. One branch placebo and other one no intervention","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04531254,"Active, not recruiting","August 10, 2020",December 2020,"Covid19,Schools","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:4 Years,Max Age:18 Years",No,240
NCT04361916,Terminated,"April 21, 2020","June 30, 2020",COVID-19,"N/A,Single Group Assignment,single arm, open label trial on active home monitoring strategy,Health Services Research,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,37
NCT04336410,"Active, not recruiting","April 3, 2020",July 2021,Coronavirus Infection,"Non-Randomized,Sequential Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04346355,Terminated,"March 31, 2020","June 6, 2020",COVID-19 Pneumonia,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,126
NCT04402957,Not yet recruiting,"July 1, 2020","June 30, 2021","COVID,Severe Acute Respiratory Syndrome,Sars-CoV2,Acute Kidney Injury","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:45 Years,Max Age:80 Years",No,60
NCT04498936,Recruiting,"July 15, 2020","December 30, 2020",COVID,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:12 Years,Max Age:65 Years",No,240
NCT04386876,"Active, not recruiting","April 30, 2020","June 20, 2020",Bioequivalence,"Randomized,Crossover Assignment,Single Oral Dose,Two Treatment,Four-period,Full-replicated,Cross-over,Other,None (Open Label)","gender:Male,Min Age:20 Years,Max Age:40 Years",No,30
NCT04409262,Recruiting,"June 16, 2020","December 1, 2020",COVID-19 Pneumonia,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:12 Years,Max Age:N/A",No,450
NCT04460443,Recruiting,"August 1, 2020","August 31, 2021",COVID,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,60
NCT04530357,Enrolling by invitation,"September 19, 2020","April 30, 2021","Covid19,SARS-CoV Infection,Vaccine Adverse Reaction","Randomized,Parallel Assignment,Prevention,Single (Participant)","gender:All,Min Age:18 Years,Max Age:100 Years",No,244
NCT04474067,Recruiting,"June 28, 2020","December 1, 2020",COVID-19,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04542941,"Active, not recruiting","June 16, 2020","October 31, 2020",Covid19,"Randomized,Parallel Assignment,This study will be a prospective randomized two arm open label clinical trial. Patients with confirmed COVID-19 who meet the study eligibility criteria will be randomized to receive either CCP in addition to standard of care therapy or standard of care therapy alone.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:100 Years",No,136
NCT04565067,Recruiting,"October 12, 2020","September 1, 2022",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04355741,Completed,"April 20, 2020","July 16, 2020",COVID-19,"Case-Only,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,115
NCT04405739,Recruiting,"June 16, 2020","November 25, 2020",SARS-CoV 2,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,89
NCT04350580,Recruiting,"April 11, 2020",June 2021,"Acute Respiratory Distress Syndrome,COVID-19","Randomized,Parallel Assignment,The participant will be randomized to either the group of treatment with IVIG or the placebo group. Participants in the treatment group will receive infusions of polyvalent immunoglobulins for 4 consecutive days. Participants in the placebo group will receive an equivalent volume of sodium chloride 0.9% for the same duration.,Treatment,Double (Participant, Care Provider),The double blinding will be provided by the hospital pharmacy of each establishment with the help of opaque sleeves to mask the product packaging and should be returned to the pharmacy when empty.","gender:All,Min Age:18 Years,Max Age:N/A",No,138
NCT04335019,Not yet recruiting,April 2020,May 2020,"2019-nCoV (COVID-19),Interstitial Pneumonia","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04535856,Not yet recruiting,"September 11, 2020","December 31, 2020","Covid19,Corona Virus Infection,SAR","Randomized,Parallel Assignment,Randomized, Double-blind, and Placebo-controlled Clinical Trial,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double-blind, To maintain the double-blind of the study, a statistician who do not participate in this study will independently generate randomization code only using the PLAN procedure (Proc Plan procedure) of SAS (ver. 9.4 or higher, SAS Institute, Cary, NC, USA).","gender:All,Min Age:19 Years,Max Age:N/A",No,9
NCT04480060,Completed,"March 10, 2020","July 14, 2020",Covid19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:50 Years",No,100000
NCT04511650,Recruiting,September 2020,February 2021,"COVID-19,Acute Respiratory Distress Syndrome","Randomized,Parallel Assignment,Treatment,Triple (Participant, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,180
NCT04504240,Recruiting,"August 1, 2020","October 30, 2020",Covid19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:16 Years,Max Age:80 Years",No,200
NCT04395755,Completed,"April 1, 2020","May 15, 2020","Infertility, Female,ART,IVF,COVID-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:N/A",No,503
NCT04522310,Recruiting,"May 20, 2020","October 7, 2020",Covid19,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,183
NCT04394884,Recruiting,"October 12, 2020","April 30, 2023",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,160
NCT04568811,"Active, not recruiting","September 26, 2020","September 27, 2021",Adenovirus Type-5 Vectored COVID-19 Vaccine,"N/A,Single Group Assignment,Prevention,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,89
NCT04364763,Recruiting,"August 5, 2020","December 31, 2021",COVID-19,"Randomized,Parallel Assignment,2:1 randomization to receive RBT-9:Placebo,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,252
NCT04354428,"Active, not recruiting","April 16, 2020",December 2020,"COVID-19,SARS-CoV-2","Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:80 Years",No,231
NCT04318301,Completed,"March 21, 2020","March 30, 2020","COVID-19,Hypertension","Case-Control,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,275
NCT04468308,Recruiting,"September 8, 2020",March 2021,Senile Cataract,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:50 Years,Max Age:N/A",No,116
NCT04333875,"Active, not recruiting","March 20, 2020",December 2020,Aortic Valve Stenosis,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,71
NCT04389333,Completed,"March 26, 2020","May 20, 2020","Gastrointestinal Disease,Infectious Disease,Capsule Endoscopy","Randomized,Parallel Assignment,The investigators recruited 40 patients who have related symptom and healthy people mainly from outpatient clinic or hostipal health examination center. After fully understanding the procedure of nc-MCE，patients with informed consent were randomly divided into MCE group and nc-MCE group(1:1) by using a stratified block randomization(block size four),Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,40
NCT04272710,Withdrawn,"January 25, 2020","April 30, 2020",2019-nCoV,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,0
NCT04384380,Completed,"April 1, 2020","May 31, 2020",Coronavirus Infection,"Randomized,Parallel Assignment,The study will employ an open-label parallel design, to evaluate the efficacy and safety between hydroxychloroquine sulfate (plaquenil) and controlled standard of care treatment. The administration plan of HCQ is 400 mg bid on Day 1 and 200 mg bid for 6 days on Day 2-7. All of the enrolled subjects will receive standard of care. The comparison group will receive standard of care, i.e., supportive treatment for subjects with mild COVID-19 clinical illness.,Treatment,None (Open Label)","gender:All,Min Age:20 Years,Max Age:79 Years",No,33
NCT04446338,Recruiting,"May 13, 2020",August 2020,"History of Covid-19, Seroprevalence","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,300
NCT04391738,"Active, not recruiting","February 1, 2020","September 30, 2020",SARS-CoV 2,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1200
NCT04344288,Recruiting,"April 21, 2020",November 2020,"Viral Pneumonia Human Coronavirus,COVID-19","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,304
NCT04403269,Recruiting,"May 5, 2020","May 5, 2021",Sars-CoV2,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:75 Years,Max Age:N/A",No,35
NCT04523610,Not yet recruiting,October 2020,October 2022,"Depression, Anxiety,Cognitive Impairment,Stress","N/A,Single Group Assignment,This is a mixed-methods (qualitative and quantitative) model,Health Services Research,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,258
NCT04452487,Recruiting,"June 1, 2020",June 2021,"Patient Hospitalized in Disease Infectious Unit,Patient Hospitalized in Intensive Reanimation Unit,Patient Hopsitalized in Internal Medicine Unit","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2500
NCT04397796,Recruiting,"August 3, 2020",June 2021,COVID,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:80 Years",No,45
NCT04436276,Recruiting,"July 15, 2020","November 20, 2023",Healthy,"Randomized,Parallel Assignment,Other,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,1045
NCT04558021,Recruiting,"September 28, 2020","January 7, 2021",Covid19,"Randomized,Parallel Assignment,200 patients will receive either 200 mg niclosamide in 10 mL of suspension or 10 mL of placebo three times a day together with an established treatment regimen in 1:1 ratio. The study will be conducted in 2 parts: an interim analysis will be conducted after the first 100 patients.,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04365881,Completed,"March 31, 2020","April 7, 2020","Loneliness, Worry, Rumination, Health Anxiety, Depression, Anxiety","Other,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,10084
NCT04361981,Not yet recruiting,April 2020,"December 31, 2020",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,50
NCT04245631,Recruiting,"January 1, 2020","December 31, 2020",New Coronavirus,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:1 Year,Max Age:90 Years",No,50
NCT04375501,Completed,"February 1, 2020","April 15, 2020","Femoral Neck Fractures,SARS-CoV 2","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,442
NCT04337788,Not yet recruiting,May 2020,September 2020,Coronavirus Infection,"Non-Randomized,Parallel Assignment,Prospective cohort study (here and elsewhere),Prevention,None (Open Label)","gender:All,Min Age:75 Years,Max Age:N/A",No,200
NCT04467112,Recruiting,"July 30, 2020",December 2020,COVID,"Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:16 Years,Max Age:N/A",No,100
NCT04500418,Recruiting,"August 25, 2020","September 30, 2021",Covid19,"Randomized,Parallel Assignment,A monocentric, randomized, double-blind, placebo-controlled trial.
Randomization will be stratified by:
Presence of baseline score of ""3"" on 7-point ordinal scale versus presence of baseline score of ""4"" or ""5"" on seven-point ordinal scale
Presence of one or more of the following comorbidities: Diabetes mellitus, Obesity (BMI >30kg/m2), COPD or Asthma, Heart failure (NYHA Class I or II),Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,183
NCT04457609,Recruiting,July 2020,September 2020,"COVID,Pulmonary Infection,Sars-CoV2","Randomized,Parallel Assignment,Treatment,Triple (Participant, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:95 Years",No,40
NCT04474080,Not yet recruiting,July 2020,July 2021,Burnout,"Randomized,Crossover Assignment,The following trial uses a nested stepped-wedge RCT design. Specialty residency programs will be the unit of randomization, with each program being randomized to receive the virtual peer support intervention across varying time-points.,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,1080
NCT04490811,Recruiting,"April 9, 2020","December 31, 2021",COVID-19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:18 Years",No,800
NCT04365725,Recruiting,"May 5, 2020",June 2020,COVID-19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04355364,Recruiting,"April 21, 2020","August 21, 2020","COVID-19,Acute Respiratory Distress Syndrome","Randomized,Parallel Assignment,Dornase alfa will be administered by nebulization, at a dose of 2500 IU twice daily, 12 hours apart, for 7 consecutive days, using a vibrating mesh nebulizer. The remainder of the management will be performed in accordance with good practice, including mechanical ventilation (protective ventilation, PEEP > 5 cmH2O, tracheal balloon pressure checking every 4 hours or automatic device, 30° head of the bed elevation, tidal volume 6-8mL/kg, plateau pressure < 30cmH2O), neuromuscular blockers if necessary, prone position if PaO2/FiO2<150, early enteral nutrition, glycemic control, a sedation protocol based on the RASS score.tracheal balloon pressure checking every 4 hours or automatic device, 30° head of the bed elevation, tidal volume 6-8mL/kg, plateau pressure < 30cmH2O), neuromuscular blockers if necessary, prone position if PaO2/FiO2<150, early enteral nutrition, glycemic control, a sedation protocol based on the RASS score.,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04424004,Enrolling by invitation,"June 9, 2020","June 30, 2021",COVID 19,"Ecologic or Community,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04252664,Suspended,"February 12, 2020","April 27, 2020","COVID-19,SARS-CoV-2","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,308
NCT04354441,Withdrawn,May 2020,May 2020,"COVID-19,SARS-CoV-2,Pregnant Women,Hydroxychloroquine","Randomized,Parallel Assignment,Participants will be randomized 1:1 to receive either the study medication (hydroxychloroquine) or an identical-looking placebo. Randomization will be in blocks of 4-6, stratified by province.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:Female,Min Age:18 Years,Max Age:50 Years",No,0
NCT04435808,Recruiting,"April 14, 2020","April 14, 2025",COVID-19,"Non-Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,350
NCT04370210,Completed,"May 4, 2020","June 4, 2020",Sleep Disturbance,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:7 Years,Max Age:12 Years",No,247
NCT04383574,"Active, not recruiting","May 22, 2020","May 30, 2021",COVID-19,"Randomized,Parallel Assignment,Prevention,Double (Participant, Investigator)","gender:All,Min Age:60 Years,Max Age:N/A",No,422
NCT04463602,Recruiting,"July 25, 2020","January 30, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,24
NCT04500652,Recruiting,"June 27, 2020","October 1, 2020","Anxiety,Depression,Insomnia,Covid19,Coronavirus","Other,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:24 Years,Max Age:80 Years",No,310
NCT04544072,Recruiting,"May 1, 2020","March 1, 2021","SARS-CoV Infection,Antimicrobial Stewardship,Respiratory Tract Infections,Antibiotic Resistance","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04417673,Not yet recruiting,"October 12, 2020","December 31, 2024","Isolation,Anxiety,Health Care Utilization,Sickle Cell Disease,Pain","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04396197,Completed,"March 1, 2020","May 8, 2020","COVID-19,Critical Illness,Ards,ICU Acquired Weakness","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,92
NCT04418245,"Active, not recruiting","March 1, 2020",July 2020,Covid-19,"Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1000
NCT04368871,Recruiting,"April 28, 2020","May 30, 2021",COVID,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:75 Years",No,200
NCT04455360,Not yet recruiting,"August 1, 2020",May 2021,"Post Traumatic Stress Disorder,Intensive Care Psychiatric Disorder,Anxiety Disorders,Depression,Critical Care,COVID","Randomized,Parallel Assignment,Supportive Care,None (Open Label),Patient reported outcomes at 6-months post-hospital discharge","gender:All,Min Age:18 Years,Max Age:N/A",No,26
NCT04346082,Not yet recruiting,"August 1, 2020","July 30, 2021",Stress,"N/A,Single Group Assignment,participants receiving online mindfulness session(s),Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04414826,Recruiting,"May 25, 2020",May 2021,Loneliness,"Randomized,Parallel Assignment,Participants will be randomized to one of three groups: (a) Mindfulness alone; (b) Mindfulness + Compassion; and (c) Wait-list control.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,120
NCT04357327,Recruiting,"April 16, 2020","July 31, 2020","COVID-19,SARS-CoV 2,Corona Virus Infection","Non-Randomized,Parallel Assignment,Consecutive recruitment of both patients with COVID-19 like symptoms (i.e., cough, fever, dyspnea) and patients with low risk phenotype,Diagnostic,Single (Outcomes Assessor),The rapid salivary test will provide results within 5-10 minutes, while the rRT-PCR performed on nasopharyngeal swab shows results only after 6 hours, thus the outcome assessor of the experimental test is blinded","gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04395794,Recruiting,"May 7, 2020","November 30, 2020",Sars-CoV2,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,900
NCT04323228,Recruiting,"September 1, 2020","December 30, 2020",COVID-19,"Randomized,Parallel Assignment,Participants will be randomly allocated into two study groups; intervention group (IG, n=20) and placebo group (PG, n=20). Computer-generated random numbers will be used to randomize the participants into one of two intervention groups.,Supportive Care,Double (Participant, Care Provider),The intervention-supplement and isocaloric-placebo will be served in the same shape, size and color. the care providers (nurses, dietitians) will not know members of each groups or the nature or composition of the ONS.","gender:All,Min Age:18 Years,Max Age:65 Years",No,40
NCT04495803,Not yet recruiting,"August 10, 2020","August 1, 2022","Perinatal Anxiety,Covid19","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:Female,Min Age:18 Years,Max Age:45 Years",No,120
NCT04567576,Not yet recruiting,October 2020,"October 31, 2021","Rheumatic Diseases,Covid19","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,150
NCT04367831,Recruiting,"May 2, 2020",April 2021,"COVID-19,Venous Thromboses,Arterial Thrombosis","Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:80 Years",No,100
NCT04548531,Enrolling by invitation,"September 10, 2020","May 30, 2021",Colon Cancer,"Randomized,Parallel Assignment,Two-armed randomized control trial,Health Services Research,Single (Outcomes Assessor),Patients will not be given any information on their assigned arm. Statistician will be blinded to the assignment when analyzing the results.","gender:All,Min Age:45 Years,Max Age:75 Years",No,800
NCT04428268,Recruiting,"March 10, 2020","August 30, 2020",COVID-19 Pneumonia,"Randomized,Parallel Assignment,double blind randomized clinical trial,Treatment,Double (Investigator, Outcomes Assessor),investigator will not be aware of the treatments or outcomes until the end of the study","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04342637,Completed,"April 10, 2020","May 1, 2020",COVID-19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:30 Years,Max Age:70 Years",No,163
NCT04400305,Recruiting,"May 20, 2020",September 2020,"Physical Activity, Healthy Promotion","Randomized,Parallel Assignment,Parallel Assignment,Other,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04570449,Not yet recruiting,September 2020,October 2021,Covid19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04336904,"Active, not recruiting","March 25, 2020",July 2020,COVID-19,"Randomized,Parallel Assignment,This is a multi-center, randomized, double-blind, placebo-controlled (1:1) clinical study to explore the efficacy and safety of Favipiravir in the treatment of adult subjects with COVID-19-moderate type.
Subjects within 10 days of COVID-19 onset will be screened, and be randomized as early as possible within 24 hours following screen success.
It is planned to randomize 100 subjects in an 1:1 ratio. Subjects in the test group will receive supportive care recommended in the current guidelines+Favipiravir, and subjects in the control group will receive supportive care recommended in the current guidelines+placebo control; the efficacy and safety of Favipiravir versus the placebo in the treatment of COVID-19-moderate type will be compared.,Treatment,Double (Participant, Care Provider)","gender:All,Min Age:18 Years,Max Age:75 Years",No,100
NCT04355338,Not yet recruiting,"May 15, 2020","May 15, 2022",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,4100
NCT04395742,Not yet recruiting,May 2020,December 2020,Coronavirus Disease 2019,"Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,93
NCT04479540,Recruiting,"May 26, 2020","August 31, 2021","Pneumonia, Viral","N/A,Single Group Assignment,Determination of incidence of occurrence of pulmonary embolism in hospitalized patients with SARS-CoV-2 pneumonitis, first by performing systematic thoracic angiography scanner in all hospitalized patients and then to explore hemostasis profile,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04535167,Recruiting,"September 9, 2020","March 21, 2021",Viral Disease,"Randomized,Sequential Assignment,Part 1 will have 3 planned cohorts. Each cohort will be initiated for enrollment after assessment of safety, tolerability and PK data from previous cohorts by an independent IRC and is deemed acceptable.
Part 2 will be initiated after all safety, tolerability and PK data from Part 1 is evaluated and is deemed acceptable.,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:75 Years",No,56
NCT04400812,Enrolling by invitation,"May 19, 2020",October 2020,COVID-19,"Other,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:16 Years,Max Age:70 Years",No,5000
NCT04332835,Recruiting,"August 8, 2020","October 31, 2020","Coronavirus,Coronavirus Infection","Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor),Single Blinded","gender:All,Min Age:18 Years,Max Age:100 Years",No,90
NCT04550338,Not yet recruiting,"December 1, 2020","March 31, 2023",COVID-19,"Randomized,Parallel Assignment,Placebo-controlled, double-blind, randomized, controlled trial,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Once patient is consented, pharmacy will randomize to one of two arms and prepare coded sets of drugs","gender:All,Min Age:18 Years,Max Age:80 Years",No,100
NCT04311177,Recruiting,"April 9, 2020","April 1, 2021","Corona Virus Infection,Acute Respiratory Distress Syndrome,SARS-CoV Infection","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,580
NCT04482673,Recruiting,"July 31, 2020","December 31, 2021","COVID-19,Vitamin D Deficiency,Respiratory Viral Infection","Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:50 Years,Max Age:N/A",No,140
NCT04345861,Terminated,"April 11, 2020","June 8, 2020","Coronavirus Infection,Pneumonia, Viral","Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:75 Years",No,7
NCT04374695,Not yet recruiting,"May 1, 2020","July 1, 2020",COVID-19,"Case-Control,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,700
NCT04341766,Completed,"March 31, 2020","June 30, 2020","Pneumonia, Viral,COVID-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:105 Years",No,106
NCT04569188,Completed,"May 15, 2020","September 3, 2020",COVID-19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:65 Years,Max Age:N/A",No,21
NCT04509986,Not yet recruiting,"October 1, 2020","December 1, 2020","Surgery,Covid19,Post-Op Complication","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1000
NCT04469491,Not yet recruiting,July 2020,March 2021,"COVID-19,INTERFERON,NEBULIZATION","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04497623,Completed,"July 28, 2020","September 20, 2020",Covid19,"N/A,Single Group Assignment,Enrolled patients receive mechanical ventilation using the Unisabana-Herons ventilator during 24 hours,Device Feasibility,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,5
NCT04369456,Recruiting,"April 22, 2020","October 22, 2020","Kidney Transplant; Complications,Coronavirus Infection","N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:85 Years",No,115
NCT04341870,Suspended,"April 11, 2020",August 2020,"COVID19,SARS-CoV-2 Infection","Randomized,Parallel Assignment,Bayesian open labelled randomized clinical trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,27
NCT04496869,Not yet recruiting,July 2020,December 2020,"Infertility Treatment,Women","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:43 Years",No,600
NCT04483635,Not yet recruiting,"September 1, 2020","June 30, 2021",COVID-19,"Randomized,Parallel Assignment,Parallel-group, placebo controlled trial of vitamin D3 supplementation,Prevention,Triple (Participant, Investigator, Outcomes Assessor),The Laboratoires Riva will provide the active vitamin D3 and placebo pills, identical in appearance, which will be pre-packaged in coded 60-pill bottles. A web-based randomisation system will allow the research personnel (RP) to log in, obtain a randomization number, and dispense study drugs, pre-prepared by the Central pharmacy, in masked kits.","gender:All,Min Age:18 Years,Max Age:69 Years",No,2414
NCT04425915,Recruiting,"June 14, 2020","May 30, 2021",COVID,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04448405,Recruiting,"June 18, 2020","October 30, 2020",Deviant Sexual Fantasies,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04345653,"Active, not recruiting","April 14, 2020","April 8, 2021",COVID19,"N/A,Single Group Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:99 Years",No,44
NCT04500639,Recruiting,"July 23, 2020","March 31, 2023","SARS-CoV-2 Infection,Covid19","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,14000
NCT04576351,Recruiting,"September 1, 2020","December 31, 2023",Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04373109,Recruiting,"April 16, 2020",April 2021,"Stroke,Rehabilitation,COVID-19,Cohort Studies","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,70
NCT04427280,Recruiting,"May 26, 2020",April 2021,"Infectious Disease,Cancer,Coronavirus Infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04282135,Completed,"February 15, 2020","June 30, 2020",Influenza,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,76
NCT04559100,Not yet recruiting,"October 1, 2020","October 1, 2021",Covid19,"Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,112
NCT04332991,Completed,"April 2, 2020","July 23, 2020","Coronavirus,Acute Respiratory Infection,SARS-CoV Infection","Randomized,Parallel Assignment,Eligible participants will be randomized 1:1 to hydroxychloroquine versus placebo. Randomization will be stratified by site and be in permuted blocks of variable size.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Patients, treating clinicians, trial personnel, and outcome assessors will be blinded to group assignment.","gender:All,Min Age:18 Years,Max Age:N/A",No,479
NCT04475484,Recruiting,"June 10, 2020","December 31, 2020","Investigating Psychological Impact,Confinement Measures,Coronavirus Outbreak,School-age Children","Ecologic or Community,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:6 Years,Max Age:18 Years",No,30000
NCT04348071,Not yet recruiting,November 2020,October 2021,COVID-19,"N/A,Single Group Assignment,This is a single arm, open label, single site study. Data from participants in this study with data from other COVID-19 patients not receiving ruxolitinib.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:89 Years",No,80
NCT04409834,Recruiting,"August 5, 2020",May 2021,"COVID-19,Venous Thromboembolism,Arterial Thrombosis","Randomized,Factorial Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,750
NCT04373460,Recruiting,"June 3, 2020","January 31, 2023",SARS-CoV 2,"Randomized,Parallel Assignment,A total of approximately 600 eligible subjects stratified 50:50 in the <65 vs ≥ 65 age range will be randomized in a 1:1 ratio to receive either HCIP or control plasma.,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,1344
NCT04525443,Recruiting,"June 3, 2020","September 30, 2020",COVID-19,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04377711,Recruiting,"June 8, 2020","December 1, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator),Double Blind","gender:All,Min Age:12 Years,Max Age:100 Years",N/A,400
NCT03474965,Recruiting,"October 1, 2018","November 20, 2024",Sickle Cell Disease (SCD),"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:6 Months,Max Age:17 Years",N/A,100
NCT04459702,Not yet recruiting,July 2020,December 2021,"COVID,COVID-19,Corona Virus Infection,Coronavirus Infection,Coronavirus Sars-Associated as Cause of Disease Classified Elsewhere,Coronavirus-19,SARS-CoV 2,SARS Pneumonia","Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:65 Years",No,200
NCT04444531,Completed,"March 20, 2020","May 26, 2020",COVID-19 Pneumonia,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,18
NCT04337320,Completed,"March 15, 2020","May 30, 2020","Covid19,Maternal-Fetal Relations","Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:15 Minutes",No,40
NCT04361877,Recruiting,"March 30, 2020","April 20, 2020",Cardiovascular Prevention Behaviour,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1900
NCT04537663,Recruiting,"August 25, 2020",April 2021,"Respiratory Tract Infections,Covid19","Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Placebo consists of intradermal injection of sterile 0.9% NaCl.","gender:All,Min Age:60 Years,Max Age:N/A",No,5200
NCT04544033,Recruiting,"September 15, 2020",January 2021,Covid19,"Case-Only,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,120
NCT04324684,Completed,"March 31, 2020","May 7, 2020","Pneumonia, Viral,Hypertension,Diabetes Mellitus,Obesity,Cardiovascular Diseases,Obstructive Lung Disease","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,198
NCT04408378,Recruiting,"June 5, 2020","August 20, 2020",Coronavirus Infection,"Case-Control,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:70 Years",No,156
NCT04431310,Recruiting,"March 27, 2020","August 1, 2025","Covid-19,Health Personnel,Personnel, Hospital","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04346966,Not yet recruiting,"August 20, 2020","November 20, 2020","Social Isolation,Exercise,Healthy","Randomized,Parallel Assignment,Prevention,Single (Participant)","gender:All,Min Age:18 Years,Max Age:40 Years",No,128
NCT04389320,Completed,"March 15, 2020","May 1, 2020",Rheumatoid Arthritis,"Cohort,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:20 Years,Max Age:70 Years",No,60
NCT04345406,Not yet recruiting,"April 15, 2020","December 1, 2029",COVID,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,60
NCT04445402,Recruiting,"April 30, 2020","May 1, 2022","Pediatric Cancer,Immune System Disorder,COVID-19,Hemoglobinopathies","Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:21 Years",No,1500
NCT04353128,Recruiting,"April 20, 2020",December 2020,"Covid19,SARS-CoV 2,Coronavirus Infection","Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:65 Years",No,450
NCT04366115,Not yet recruiting,November 2020,June 2023,"Covid19,Acute Respiratory Distress Syndrome","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,8
NCT04341506,Recruiting,"September 8, 2020","December 15, 2021",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04349618,Not yet recruiting,"April 14, 2020","April 14, 2022","Acute Respiratory Distress Syndrome,COVID19,Sars-CoV2,Pneumonia","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04423042,Not yet recruiting,"July 30, 2020",June 2021,"Covid19,COVID-19,Severe Acute Respiratory Syndrome Coronavirus 2,Coronavirus,Inflammation","Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT03680274,Recruiting,"November 8, 2018","December 31, 2022","Sepsis,Vitamin C,Intensive Care Unit,COVID-19,Pandemic,Coronavirus","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,800
NCT04457388,Completed,"March 25, 2020","June 15, 2020",Chronic Pain,"N/A,Single Group Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:60 Years",No,18
NCT04408248,Recruiting,"August 20, 2020","June 30, 2021","COVID,Acute Respiratory Failure,Acute Kidney Injury","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04459975,Recruiting,"April 1, 2020",November 2020,"on Occurrence of Acurate Kidney Injury During Intensive Care Unit,Abnormalities of Urinary Analysis","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04453839,Available,N/A,N/A,N/A,N/A,"gender:All,Min Age:12 Years,Max Age:100 Years",N/A,N/A
NCT04251871,Recruiting,"January 22, 2020","January 22, 2021",Pneumonia Caused by Human Coronavirus (Disorder),"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:14 Years,Max Age:80 Years",No,150
NCT04529460,Not yet recruiting,"September 1, 2020","April 30, 2021",Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04377789,Recruiting,"March 20, 2020","August 31, 2020",COVID-19,"Non-Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04326114,Not yet recruiting,"July 26, 2020","December 20, 2020","Disease, Infectious,Respiratory Disease,Safety Issues,Effectiveness","Randomized,Parallel Assignment,Prevention,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,240
NCT04326452,Recruiting,"March 27, 2020","March 27, 2021",Coronavirus Infection,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04363385,Recruiting,"May 31, 2020","May 31, 2021",Covid-19,"N/A,Single Group Assignment,Collection of blood samples in a cohort of Covid-19 patients,Prevention,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,500
NCT04377581,Completed,"April 9, 2020","July 10, 2020","Public Health,Demography,Pandemics,Corona Virus Infection,News,Global Health,Perception","Ecologic or Community,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,18251
NCT04415060,Recruiting,"June 15, 2020","June 15, 2023",Covid19,"Randomized,Parallel Assignment,Multicentre open-label, pragmatic, randomized controlled trial and a parallel prospective (non-randomized) cohort study,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,752
NCT04474301,Recruiting,"June 11, 2020","July 1, 2021","COVID-19 Infection,Melanoma","Case-Only,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1152
NCT04426305,Enrolling by invitation,"May 21, 2020","October 30, 2020","Covid 19,Social Isolation,Mental Health Impairment","Randomized,Parallel Assignment,Supportive Care,Single (Care Provider)","gender:All,Min Age:18 Years,Max Age:N/A",No,140
NCT04367064,Recruiting,"April 25, 2020","December 25, 2020",COVID,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:75 Years",No,1000
NCT04536051,Recruiting,"June 2, 2020",September 2021,Coronavirus,"Randomized,Sequential Assignment,Prevention,Single (Participant)","gender:All,Min Age:18 Years,Max Age:N/A",No,5000
NCT04479631,Recruiting,"July 12, 2020",March 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:49 Years",No,12
NCT04562246,Recruiting,"August 14, 2020",August 2021,Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04527354,Recruiting,"September 8, 2020",November 2020,"SARS-CoV-2 Infection,Fibrosis Lung","Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator),A blind will be performed by using Placebo equivalent to Treamid tablets without active substance and the corresponding labeling of the study drug.","gender:All,Min Age:18 Years,Max Age:75 Years",No,60
NCT04360850,Recruiting,"April 24, 2020",October 2025,Online Therapy,"Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,10000
NCT04382092,Completed,"March 23, 2020","April 24, 2020",COVID-19,"N/A,Single Group Assignment,prospective interventional study,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,32
NCT04411433,Recruiting,"May 8, 2020","July 30, 2020","Sars-CoV2,COVID-19","Randomized,Parallel Assignment,This is an open-label, multicenter, parallel-group, randomized, phase III trial that evaluates the efficacy and safety of hydroxychloroquine and favipiravir in the treatment of patients with possible or confirmed COVID-19 observed within the last 5 days. 1000 patients will be randomized in 2:1:2:2:2:1 ratio and divided into six groups.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,1000
NCT04336384,Recruiting,"March 1, 2020","December 30, 2020","Congenital Heart Disease,Covid-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,5000
NCT04412278,Completed,"June 1, 2020","June 8, 2020","COVID,Isolation, Social","Ecologic or Community,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:15 Years,Max Age:65 Years",No,392
NCT04522830,Recruiting,"July 30, 2020","October 30, 2020",SARS-CoV-2 Infection,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Investigator, Outcomes Assessor)","gender:All,Min Age:60 Years,Max Age:N/A",No,40
NCT04451889,Recruiting,"August 1, 2020","September 1, 2021",COVID-19,"N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:90 Years",No,15
NCT04424992,"Active, not recruiting","February 23, 2020",December 2020,Sars-CoV2,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1433
NCT04492189,Completed,"April 1, 2020","June 30, 2020","Eating Disorders,COVID 19","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04478539,Recruiting,"June 1, 2020","July 1, 2021",Covid19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,35
NCT04425772,Not yet recruiting,"June 12, 2020","August 12, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:99 Years",No,342
NCT04458337,Recruiting,"March 13, 2020","April 13, 2021","Covid-19,SARS-CoV2,Surgery,Surgical Procedure; Complications, Late Effect of Complications,Postoperative Complications","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,120
NCT04335032,Not yet recruiting,"April 13, 2020","July 31, 2020",SARS-CoV-2,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:85 Years",No,240
NCT04381312,Recruiting,"April 9, 2020","October 9, 2021",Risk Factors for COVID-19 Outcomes in Elderly Populations,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:70 Years,Max Age:N/A",No,1000
NCT04433949,Recruiting,"June 12, 2020","May 30, 2022","Pneumonia,Severe Acute Respiratory Syndrome,Symptomatic COVID-19 Infection Laboratory-Confirmed","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,52
NCT04367805,Recruiting,"April 27, 2020",October 2020,"Hepatocellular Carcinoma,COVID-19","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04500626,Not yet recruiting,October 2020,August 2022,Covid19,"Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,234
NCT04483622,Recruiting,"June 12, 2020","February 15, 2021",Covid19,"Case-Only,Prospective","sampling_method:Probability Sample,gender:All,Min Age:16 Years,Max Age:90 Years",No,30
NCT04418284,Recruiting,"June 5, 2020","July 5, 2020",COVID-19,"Other,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:17 Years,Max Age:35 Years",No,400
NCT04397523,Recruiting,"April 30, 2020","April 29, 2021","Convalescent Plasma,COVID-19,SARS-CoV 2","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04370782,Recruiting,"April 28, 2020","December 31, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:30 Years,Max Age:N/A",No,750
NCT04570488,Recruiting,"May 15, 2020","May 15, 2021","COVID,Corona Virus Infection,Adverse Event","Randomized,Parallel Assignment,Display of risk score/ colored flag in Epic patient list column vs. no display (""missing""); will be viewable to all frontline workers,Health Services Research,Double (Participant, Outcomes Assessor),Participant and data analyst(s) are blinded","gender:All,Min Age:18 Years,Max Age:100 Years",No,12000
NCT04454606,Completed,"May 1, 2020","May 31, 2020","COVID,Personal Protective Equipment","N/A,Single Group Assignment,N99 respirators will be tested in a group of subjects with qualitative fit test.The filters will be tested for filtration test.The results will be considered as pass or fail,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:60 Years",No,43
NCT04515199,Recruiting,"July 1, 2020",March 2021,"Covid19,Telemedicine,Quality of Life,Safety Issues,Symptoms","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:65 Years",No,400
NCT04359212,Completed,"May 1, 2020","July 31, 2020","COVID-19 Disease,Thromboembolism, Venous","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,90
NCT04487197,Recruiting,"July 15, 2020","January 15, 2021","Kidney Transplant,Pancreatic Transplat,Pancreatic Islets Langerhans","Cohort,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04252118,Recruiting,"January 27, 2020",December 2021,COVID-19,"Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,20
NCT04473131,Recruiting,"April 27, 2020",June 2022,COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04473898,Recruiting,"June 19, 2020","December 19, 2020",COVID,"Randomized,Parallel Assignment,It is planned to include 3 groups in the study. The group 1 will be informed about covid-19 and hygiene. Aerobic exercise will be offered to Group 2, aerobic exercise + breathing exercises will be offered to Group 3. The persons to be included in the groups will be determined randomly.,Supportive Care,Single (Participant)","gender:All,Min Age:25 Years,Max Age:70 Years",No,36
NCT04370678,Completed,"April 17, 2020","April 24, 2020",Arthroscopy,"Other,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,79
NCT04345848,Recruiting,"April 28, 2020","March 31, 2021","COVID,Sars-CoV2","Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04361032,Not yet recruiting,"September 4, 2020","October 4, 2020","COVID19,Intensive Care Unit","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,260
NCT04330599,Not yet recruiting,"May 5, 2020","April 1, 2025",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:16 Years,Max Age:N/A",No,12000
NCT04338347,Available,N/A,N/A,N/A,N/A,"gender:All,Min Age:18 Years,Max Age:N/A",N/A,N/A
NCT04524663,Not yet recruiting,October 2020,April 2021,Covid19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:80 Years",No,120
NCT04344041,Recruiting,"April 15, 2020",May 2021,Coronavirus,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:65 Years,Max Age:N/A",No,260
NCT04444336,Not yet recruiting,"June 22, 2020","July 13, 2020","Depression,Anxiety","Other,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,4000
NCT04357886,Not yet recruiting,May 2020,June 2020,Healthy,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:15 Years,Max Age:N/A",No,1000
NCT04344184,Not yet recruiting,October 2020,May 2021,"COVID-19,Lung Injury, Acute","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04491227,Enrolling by invitation,"May 5, 2020","March 31, 2023","Covid19,AKI,CKD,ESRD,Transplant;Failure,Kidney","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04407143,"Active, not recruiting","April 15, 2020","September 15, 2020","Lung Cancer,COVID,Corona Virus Infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,128
NCT04517682,Enrolling by invitation,"May 21, 2020","December 30, 2020",RNA Virus Infections,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04350281,Completed,"April 9, 2020","July 7, 2020",COVID,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04412655,"Active, not recruiting","May 5, 2020","June 2, 2020",ST Elevated Myocardial Infarction Undergoing Mechanical Reperfusion,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,6609
NCT04538456,Not yet recruiting,September 2020,January 2021,"Lung Cancer,PROM,Covid19,Psychological","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,800
NCT04433000,Recruiting,"March 15, 2020","June 10, 2020",Covid-19 Pneumonia,"Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,34
NCT04375709,Recruiting,"March 15, 2020","August 31, 2021",Covid-19 (New Coronavirus) Infection,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04410432,Recruiting,June 2020,May 2021,"SARS Cov2, Immune Response","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,63
NCT04355962,Recruiting,"April 23, 2020","March 31, 2021","ARDS, Human,Coronavirus","Randomized,Parallel Assignment,a randomized, controlled multi-center trial,Treatment,Double (Participant, Outcomes Assessor),Patients will not be informed about their group assignments, technicians processing the samples will not have any access to the ICU or the patient chart (= double-blind trial). Due to the procedures involved in volatile versus intravenous sedation, group assignment cannot be entirely concealed for the study staff and ICU doctors/nurses involved with the procedure in the ICU (pragmatic limits of blinding).","gender:All,Min Age:18 Years,Max Age:85 Years",No,64
NCT04380909,Recruiting,"May 6, 2020",April 2021,"Psychological Distress,Adjustment, Psychological,Coronavirus","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04565782,Recruiting,"September 15, 2020","December 31, 2020","SARS-CoV Infection,Corona Virus Infection,Liver Transplant Recipient,COVID-19","Cohort,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,150
NCT04432272,Recruiting,"July 16, 2020",August 2021,"COVID-19,Severe Acute Respiratory Syndrome (SARS),Coronavirus Infections","Non-Randomized,Parallel Assignment,Prospective, single health system, non-randomized, open-label study.,Treatment,None (Open Label),No parties blinded as to receipt of study article. Participant, care provider and investigator blinded to actual antibody concentration in unit of plasma provided.","gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04347512,Withdrawn,"June 2, 2020","June 2, 2020","Sars-CoV-2, Community-Acquired Pneumonia,COVID-19","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04553055,Completed,"July 20, 2020","September 15, 2020",Covid19,"Ecologic or Community,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:20 Years,Max Age:N/A",No,413
NCT04517097,Completed,"May 12, 2020","June 30, 2020",Cancer,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1680
NCT03452774,Recruiting,"January 1, 2018",December 2022,"Cancer, Metastatic,Cancer,Cancer of Pancreas,Cancer of Liver,Cancer of Stomach,Cancer Liver,Cancer of Rectum,Cancer of Kidney,Cancer of Esophagus,Cancer of Cervix,Cancer of Colon,Cancer of Larynx,Cancer, Lung,Cancer, Breast,Cancer, Advanced,Cancer Prostate,Cancer of Neck,Cancer of Skin,Neuroendocrine Tumors,Carcinoma,Mismatch Repair Deficiency,BRCA Gene Rearrangement,Non Hodgkin Lymphoma,Leukemia,Non Small Cell Lung Cancer,Cholangiocarcinoma,Glioblastoma,Central Nervous System Tumor,Melanoma,Urothelial Carcinoma,Bladder Cancer,Ovarian Cancer,Endometrial Cancer,Testicular Cancer,Breast Cancer,COVID","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1500
NCT04400877,Recruiting,"June 8, 2020","June 30, 2020","COVID-19,Venous Thromboembolism,Pulmonary Embolism,Deep Vein Thrombosis,SARS-CoV 2","Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,12000
NCT04441372,Not yet recruiting,"October 1, 2020","April 1, 2021","SARS-CoV2,COVID","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1200
NCT04387760,Recruiting,"August 11, 2020","May 14, 2021","SARS-CoV 2,COVID-19","Randomized,Parallel Assignment,This is a parallel, prospective, interventional and randomized open label pilot trial involving 150 patients with COVID-19 disease. On confirmation of SARS-CoV-2 infection subjects will be randomised to hydroxychloroquine or favipiravir or standard clinical care.,Treatment,None (Open Label)","gender:All,Min Age:21 Years,Max Age:N/A",No,150
NCT04338074,Recruiting,"June 1, 2020","December 31, 2020",COVID-19,"Randomized,Parallel Assignment,Randomized, placebo-controlled, double-blind comparison,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Pharmacy prepares 5 day packs of medications that are coded","gender:All,Min Age:19 Years,Max Age:N/A",No,100
NCT04372680,Recruiting,"April 22, 2020","September 22, 2020","COVID-19,ARDS, Human,Mechanical Ventilation","Randomized,Parallel Assignment,Multicenter, Randomized, Controlled, open-label, in parallel group,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04560413,Completed,"June 1, 2020","August 10, 2020","SARS-CoV-2,Post-stroke Depression,Anxiety and Fear","Other,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,77
NCT04344951,Recruiting,"April 6, 2020","April 30, 2021","Pneumonia, Viral,Covid-19","N/A,Single Group Assignment,Prospective, open label, Phase II study,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:90 Years",No,60
NCT04494984,Recruiting,"July 27, 2020",November 2020,Covid19,"Randomized,Sequential Assignment,This study will be an adaptive phase 2/3 investigation. First, 12 subjects will be randomly assigned to receive 1 of the 2 treatment regimens (study drug or placebo) in a 1:1 ratio. After the first 6 subjects have been enrolled and have completed 24 hours post treatment of 2nd dose, the IDMC will review the safety data and will inform whether to continue with staggered enrollment. Randomization ratio for subjects in the following stage will be 1:1. The independent data monitoring committee (IDMC) will review safety data after 12, 24, 48 and 96 patients have been enrolled in each arm. The study will then enroll a total of 121 patients in each arm. An interim analysis will be performed after 80% of recruitment has been reached (n=194). The IDMC will analyze the rate of events in the group under ""standard of care"".,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),A Double-blind, Placebo-controlled, sealed-envelope based. Access to unblinded interim results will be limited to the DMC and unblinded statistician","gender:All,Min Age:18 Years,Max Age:79 Years",No,242
NCT04373759,Recruiting,"May 2, 2020",December 2020,"Sars-CoV2,Covid-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04417153,Recruiting,"September 20, 2019","June 30, 2022","Stress, Psychological,Sleep Initiation and Maintenance Disorders","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:21 Years,Max Age:N/A",No,1000
NCT04347850,Recruiting,"February 1, 2020","December 30, 2022","SARS-CoV-2,COVID-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,500
NCT04403607,Recruiting,"May 22, 2020",August 2021,COVID,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,180
NCT04519502,Recruiting,"June 23, 2020","December 31, 2021","COVID-19,Pregnancy Complications","Cohort,Retrospective","sampling_method:Probability Sample,gender:Female,Min Age:N/A,Max Age:N/A",No,26400
NCT04552340,Recruiting,"March 16, 2020",July 2023,Covid19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1500
NCT04366960,Recruiting,"May 14, 2020",November 2020,Covid19,"Randomized,Parallel Assignment,Open-label Multicentre Prospective Controlled Randomized Trial in patients with SARS-CoV-2 infection. Patients will be randomized 1:1 to 40 mg subcutaneous enoxaparin o.d. versus 40 mg enoxaparin b.i.d within 12 hours after hospitalization.,Treatment,None (Open Label),Open label","gender:All,Min Age:18 Years,Max Age:N/A",No,2712
NCT04479319,Not yet recruiting,August 2020,August 2021,Covid19,"Case-Only,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,10000
NCT04549636,Recruiting,"September 18, 2020",December 2021,"Covid-19,Asthma,Healthy","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,92
NCT04444674,Recruiting,"June 24, 2020",December 2021,Coronavirus,"Randomized,Parallel Assignment,Four groups will be enrolled to receive either one or two doses of investigational vaccine or placebo. Follow up intensity and blood draws differ between groups,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double-blinded, placebo controlled. Pharmacist and vaccine administrators will be unblinded only. DSMB will be unblinded if required to assess safety signal","gender:All,Min Age:18 Years,Max Age:65 Years",No,2000
NCT04467151,Not yet recruiting,August 2020,December 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,96
NCT04463433,Recruiting,"February 1, 2020","January 31, 2022",Parent-child Relationship and Couple Relationship Under COVID-19 in China,"Randomized,Parallel Assignment,Prevention,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:30 Years,Max Age:60 Years",No,300
NCT04374838,Recruiting,"May 15, 2020","September 1, 2021",Covid19,"Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,20
NCT04379063,"Active, not recruiting","May 13, 2020",May 2022,"Burnout, Professional,Psychological Distress","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,342
NCT04462120,"Active, not recruiting","June 16, 2020","July 30, 2020",Covid-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,100
NCT04516759,Recruiting,"August 12, 2020",December 2020,Covid19,"Randomized,Parallel Assignment,This is a randomised double-blind study. Eligible patients will be randomly assigned to one of two groups (AZD1656 plus usual care or placebo plus usual care) on a 1:1 basis,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04401111,Recruiting,"June 16, 2020","June 15, 2021","COVID,ARDS,Quality of Life","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04364698,Recruiting,"May 7, 2020",June 2020,COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04382755,Recruiting,"May 22, 2020",September 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,81
NCT04423640,Recruiting,"April 15, 2020","August 15, 2020",SARS-CoV-2,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:16 Years,Max Age:N/A",No,200
NCT04578210,Recruiting,"September 4, 2020",March 2021,Corona Virus Infection,"Randomized,Parallel Assignment,This Phase I/II escalating-dose clinical trial is a randomized study to determine safety, tolerability, alloreactivity and efficacy of cell therapy with adoptive cell therapy of NK cells or memory T cells in patients affected by COVID-19 Donors will be patientsrecovered from COVID-19 Will be 2 arms
A: allogeneic T memory cells
B: allogeneic NK cells
There will be two consecutive phases:
The first dose escalation focuses on determining safety and the recommended dose for the second segment Phase I: Patients with SARS-CoV-2+ pneumonia and/or lymphopenia and O2Sat ≤ 94% on room air at screening, with no oxygen required or with an oxygen need of ≤ 2.5 lpm in nasal cannula, will be selected This phase has a single ascending dose design with up to 3 planned dose levels for each arm
The second phase extends the safety study Phase II: Patients with SARS-CoV-2+ pneumonia and/or lymphopenia and O2Sat ≤ 94% on room air at screening, requiring or not oxygen supplementation,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:N/A,Max Age:80 Years",No,58
NCT04380870,Recruiting,"April 11, 2020","April 11, 2025",Coronavirus Infection,"Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:114 Years",No,500
NCT04365322,Recruiting,"April 20, 2020","April 20, 2025",SARS-CoV-2 Infection,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,160
NCT04386759,Not yet recruiting,May 2020,October 2020,COVID-19,"Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,6000
NCT04348396,Recruiting,"April 3, 2020",December 2020,COVID-19,"Case-Only,Prospective","sampling_method:Probability Sample,gender:All,Min Age:65 Years,Max Age:N/A",No,300
NCT04367168,Recruiting,"May 27, 2020","April 27, 2021",COVID,"Randomized,Parallel Assignment,Double-blind placebo-controlled clinical trial to test the security and efficacy of colchicine at a dose of 1.5 mg PO at day 1 followed by 0.5 mg PO BID to complete 10 days of treatment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:70 Years",No,174
NCT04333953,Recruiting,"April 1, 2020","October 1, 2020","HIV/AIDS,COVID-19,SARS-CoV-2","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,500
NCT04352465,Not yet recruiting,"May 1, 2020","November 30, 2020",COVID-19,"Non-Randomized,Sequential Assignment,The study will be divided in 3 phases:
Phase A: subjects will be dosed 20 mg of MTX IV, once per week (total of 4 doses).
Phase B: will only start after 2nd or 3rd administration of phase A. Subjects will be dosed 30 mg of MTX IV, once per week (total of 4 doses).
Phase C: will only start after 2nd or 3rd administration of phase B. Subjects will be dosed 40 mg of MTX IV, once per week (total of 4 doses).,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,42
NCT04542876,Completed,"May 1, 2020","August 18, 2020",Covid19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,46
NCT04483375,Recruiting,"July 24, 2020","January 15, 2021",Coronavirus Disease 2019(COVID-19),"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,33
NCT04336748,Not yet recruiting,April 2020,August 2020,"Sars-CoV2,Infection Viral,Healthcare Worker,Prophylaxis","Randomized,Parallel Assignment,Prevention,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,440
NCT04442087,Recruiting,"June 19, 2020",September 2021,SARS-CoV2,"N/A,Single Group Assignment,Basic Science,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,400
NCT04473690,Not yet recruiting,"November 14, 2020","February 23, 2022",Covid19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:70 Years",No,180
NCT04477655,Recruiting,"May 3, 2020","December 30, 2020",Covid19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,200
NCT04442243,Not yet recruiting,"June 22, 2020","July 13, 2020","Post Traumatic Stress Disorder,Anxiety,Depression","Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,889
NCT04573335,Completed,"June 1, 2020","July 30, 2020","Diabetes,Covid19,Isolation, Social","Cohort,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:70 Years",No,1282
NCT04534712,Not yet recruiting,"September 1, 2020","February 1, 2021",Covid19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,100
NCT04344912,Recruiting,"March 20, 2020",August 2020,"Acute Coronary Syndrome,Heart Failure,COVID","Cohort,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04347798,Enrolling by invitation,September 2020,April 2021,"Covid-19 Infection,Rheumatoid Arthritis,Psoriatic Arthritis,Hydroxychloroquine","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04386239,Not yet recruiting,May 2020,December 2020,COVID19,"N/A,Single Group Assignment,Monocentric, escalation dose,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:84 Years",No,40
NCT04407494,Completed,"March 1, 2020","April 30, 2020",COVID-19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,809
NCT04399746,Recruiting,"March 15, 2020","June 10, 2020",COVID,"Non-Randomized,Parallel Assignment,Relation 3:1 in Combination:Control groups,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:90 Years",No,30
NCT04480333,Recruiting,"September 15, 2020","March 31, 2021","Covid19,Corona Virus Infection,Severe Acute Respiratory Syndrome,Severe Acute Respiratory Infection,Severe Acute Respiratory Syndrome (SARS) Pneumonia,Severe Acute Respiratory Syndrome of Upper Respiratory Tract,Neurodegeneration,Neuroinflammatory Response","Randomized,Crossover Assignment,The dose escalation given to healthy volunteers across the following cohorts:
NA-831 cohorts:
0.1 mg/kg NA-831, number of subjects N=2 and 2 subjects on placebos 0.2 mg/kg NA-831, number of subjects N=4 and 2 subjects on placebos 0.5 mg/kg NA-831, number of subjects N=4 and 2 subjects on placebos
GS-5734 cohorts:
mg/kg GS-5734, number of subjects N=2 and 2 subjects on placebos
mg/kg GS-5734, number of subjects N=4 and 2 subjects on placebos
4 mg/kg GS-5734, number of subjects N=4 and 2 subjects on placebos
NA-831 plus GS-5734 cohorts:
0.1 mg/kg NA-831 plus 1 mg/kg GS-5734, number of subjects N=2 and 2 subjects on placebos 0.2 mg/kg NA-831 plus 2 mg/kg GS-5734, number of subjects N=4 and 2 subjects on placebos 0.5 mg/kg NA-831 plus 4 mg/kg GS-5734, number of subjects N=4 and 2 subjects on placebos.,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:21 Years,Max Age:50 Years",No,45
NCT04355767,Enrolling by invitation,"August 11, 2020",December 2022,Covid19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,600
NCT04422379,Not yet recruiting,"June 7, 2020","August 30, 2020",COVID-19,"Cohort,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:75 Years",No,314
NCT04368065,Recruiting,"April 2, 2020","June 1, 2022",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100000
NCT04355442,Completed,"April 1, 2020","May 30, 2020","Maxillofacial Injuries,Skull Fractures,COVID-19","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,300
NCT04440007,Not yet recruiting,August 2020,March 2021,Covid-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04333914,Suspended,"April 15, 2020",August 2020,"SARS-CoV-2 (COVID-19) Infection,Advanced or Metastatic Hematological or Solid Tumor","Randomized,Parallel Assignment,COHORT 1 : Patients with mild symptoms or asymptomatic
COHORT 2 : Patients with moderate/severe symptoms,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,384
NCT04491292,Recruiting,"May 18, 2020","April 30, 2021",COVID-19 Infection,"Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,20000
NCT04497272,Not yet recruiting,"August 7, 2020","October 7, 2021",COVID 19,"N/A,Single Group Assignment,Patient with COVID-19 disease,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04536441,Completed,"April 1, 2020","June 30, 2020","Mental Health Wellness,Psychological Security,Psychological Distress","Randomized,Parallel Assignment,Prevention,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:99 Years",No,161
NCT04405908,Recruiting,"June 19, 2020","March 30, 2021",COVID-19,"Randomized,Sequential Assignment,Prevention,Triple (Participant, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:75 Years",No,150
NCT04389944,Completed,"March 31, 2020","June 30, 2020",Coronavirus Disease 2019 Infectious Disease (COVID-19 Infection),"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,15
NCT04261270,Recruiting,"February 1, 2020","July 1, 2020",2019-nCoV Pneumonia,"Randomized,Parallel Assignment,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:55 Years",No,60
NCT04369599,Enrolling by invitation,"August 11, 2020",April 2021,"Acute Respiratory Distress Syndrome,COVID-19","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,24
NCT04496076,Enrolling by invitation,"April 2, 2020","March 31, 2021","Sars-CoV2,Severe Neurologic Injury,Ischemic Stroke,Hemorrhagic Stroke,Intracerebral Hemorrhage,Subarachnoid Hemorrhage,Traumatic Brain Injury,Status Epilepticus","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04425837,Not yet recruiting,July 2020,February 2021,"Sars-CoV2,Covid-19","Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,236
NCT04563689,Recruiting,"June 18, 2020",December 2020,Covid19,"Randomized,Parallel Assignment,Other,Single (Participant)","gender:All,Min Age:18 Years,Max Age:90 Years",No,24
NCT04343183,Not yet recruiting,April 2020,June 2020,COVID-19,"Randomized,Parallel Assignment,This study will utilize a single-center sequential two-parallel-group (HBOT/Standard care) randomized controlled design with 2 looks to allow for early stop due to clear benefit/harm.,Treatment,Single (Outcomes Assessor),The biostatistician and radiologist will not know which group received HBOT.","gender:All,Min Age:18 Years,Max Age:N/A",No,48
NCT04330690,Recruiting,"March 18, 2020","May 18, 2022",COVID-19,"Randomized,Parallel Assignment,4-arms in a 1:1:1:1 ratio randomization to either the control arm, consisting of standard supportive care treatment for COVID-19, or the investigational product, lopinavir/ritonavir plus standard supportive care; hydroxychloroquine plus standard supportive care; and remdesivir plus standard supportive care
This study is intended to allow for multiple adaptations, including: i) the primary endpoint at the first interim analysis, based on performance characteristics, both in its characteristics and its timepoint, with adapted sample size calculations performed for the new primary endpoints; ii) Intervention arm, with emerging data from both internal and external to the trial, with arms being dropped or added based on pre-specified stopping rules in conjunction with the DSMB.,Treatment,None (Open Label),Endpoint assessment","gender:All,Min Age:18 Years,Max Age:N/A",No,2900
NCT04387279,Recruiting,"April 24, 2020","March 30, 2021","COVID-19,Perception, Self,Facilities and Services Utilization","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,800
NCT04347031,"Active, not recruiting","April 8, 2020","August 1, 2020","Pneumonia, Viral,Respiratory Failure","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:60 Years",No,320
NCT04323592,Completed,"March 23, 2020","May 10, 2020","Severe Acute Respiratory Syndrome (SARS) Pneumonia,Coronavirus Infections,ARDS, Human","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,173
NCT04521322,Recruiting,"July 24, 2020","November 30, 2020",Covid19,"Randomized,Parallel Assignment,Multicenter, randomized, double blind compared vs placebo,Prevention,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04409327,Recruiting,"July 11, 2020",October 2020,COVID19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:65 Years,Max Age:N/A",No,550
NCT04286503,Not yet recruiting,"February 23, 2020","February 28, 2021",Novel Coronavirus Infectious Disease (COVID-19),"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,520
NCT04409925,Not yet recruiting,June 2020,January 2021,COVID-19 Infection,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,25
NCT04244591,Completed,"January 26, 2020","April 13, 2020",COVID-19 Infections,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04337918,Recruiting,"May 8, 2020","September 30, 2020",Corona Virus Infection,"Randomized,Parallel Assignment,Multi-center, prospective, randomized, controlled, phase II, parallel group,Prevention,Single (Outcomes Assessor)","gender:All,Min Age:19 Years,Max Age:N/A",No,200
NCT04352842,Completed,"January 21, 2020","April 8, 2020","Covid19,Echocardiography","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,51
NCT04376840,Not yet recruiting,"May 15, 2020","October 15, 2021",Severe SARS-CoV2 Pneumonia,"N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,240
NCT04460651,Not yet recruiting,July 2020,December 2020,COVID19,"Randomized,Parallel Assignment,Simple, pragmatic, double-blind, placebo-controlled trial,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,1500
NCT04407156,Completed,"June 1, 2020","July 20, 2020","COVID,AKI","Case-Control,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:110 Years",No,724
NCT04402814,Recruiting,"May 5, 2020","December 1, 2020",SARS-CoV 2,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,90
NCT04497467,Recruiting,"August 1, 2020","December 31, 2020",Patient Preference,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1200000
NCT04453982,Recruiting,"June 21, 2020",February 2021,"Sars-CoV2,Breastmilk","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,500
NCT04312243,Recruiting,"April 7, 2020","April 7, 2022","Coronavirus Infections,Healthcare Associated Infection","Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:99 Years",No,470
NCT04372017,"Active, not recruiting","May 14, 2020","June 4, 2021","COVID-19,SARS-CoV 2","Randomized,Parallel Assignment,Prevention,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,1
NCT04344964,Completed,"April 15, 2020","July 3, 2020","Colon Polyp,Colon Disease,Reflux, Gastroesophageal,Varices, Esophageal","Case-Control,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,186
NCT04397757,Recruiting,"May 13, 2020","March 31, 2021",COVID-19,"Randomized,Parallel Assignment,Participants will be randomized 1:1 to receive either convalescent plasma on Study Day 1 in addition to standard care or standard care alone.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04470258,Not yet recruiting,August 2020,December 2020,"COVID-19,Respiratory Failure With Hypoxia","Non-Randomized,Parallel Assignment,Device Feasibility,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,10
NCT04390412,"Active, not recruiting","May 4, 2020",December 2020,"COVID,SARS (Severe Acute Respiratory Syndrome)","N/A,Single Group Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:60 Years,Max Age:N/A",No,5
NCT04461340,Recruiting,"August 15, 2020","November 30, 2020",COVID 19,"Randomized,Parallel Assignment,single-blinded randomized clinical trial in which participants will be randomly assigned to one of the study groups using block randomization with a ratio of 1:1.,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04407468,Completed,"May 1, 2020","July 13, 2020","COVID,ARDS,Pneumonia","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,827
NCT04470544,Recruiting,"July 28, 2020","September 15, 2022",Severe Acute Respiratory Syndrome,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,264
NCT04483271,Not yet recruiting,"August 5, 2020","December 5, 2020","Cytokine Storm,Cytokines","Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:30 Years,Max Age:66 Years",No,100
NCT04328272,Not yet recruiting,"March 28, 2020","June 28, 2020",COVID19,"Randomized,Parallel Assignment,three parallel groups randomly asserted for intervention,Treatment,Single (Participant),Single blinded:
As, the disease is novel and putting the lives at risk is unethical. therefore, It is important for investigator to know the group and carry close regular monitoring of participants so that proper further intervention can be made when required.","gender:All,Min Age:18 Years,Max Age:50 Years",No,75
NCT04409743,Recruiting,"June 7, 2020",November 2021,"Sleep Disturbance,Insomnia","Randomized,Parallel Assignment,Prevention,Single (Participant)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04371289,Not yet recruiting,April 2020,"September 10, 2020","COVID-19,Cardiovascular Risk Factor","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,5500
NCT04408183,Recruiting,"June 1, 2020",November 2020,"SARS-CoV 2,Infection","Randomized,Parallel Assignment,Prevention,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,225
NCT04377425,Withdrawn,"May 7, 2020","June 30, 2022","Neurological Diseases or Conditions,Stroke, Acute,Seizure Disorder","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04453514,Recruiting,"July 21, 2020",October 2020,Anxiety,"N/A,Single Group Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04441047,Not yet recruiting,"October 6, 2020","December 31, 2021",Virus Diseases,"N/A,Single Group Assignment,Subjects over 65yo in two cohorts: ages 65-74 and age 75+,Prevention,None (Open Label)","gender:All,Min Age:65 Years,Max Age:N/A",No,40
NCT04363541,Not yet recruiting,April 2020,November 2020,"COVID-19,Thermotherapy","Randomized,Parallel Assignment,The application of an electric chest pad. The use of an electric cushion was chosen because it is designed to be used in human thermal therapy. The electric cushion provides a continuous hour of regulated heat, with enough penetration to raise the external temperature of the area to 40-42 ° C in which the death of the virus is expected.
It is a therapy designed to decrease viral load. It is not expected to have an effect on concomitant microorganisms such as bacteria or opportunists such as Candida albicans, so that when the concomitant infection is suspected, the antibiotic of choice should be given or continued, depending on the nature of the infection.,Treatment,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,298
NCT04347369,Recruiting,"January 17, 2020","December 31, 2020",COVID-19 Disease,"Case-Only,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,1000
NCT04324736,Recruiting,"March 10, 2020","September 10, 2020","Coronavirus,Diabetes","Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,5497
NCT04366921,Recruiting,"April 10, 2020",April 2021,"COVID,SARS-CoV-2,ARDS, Human,Refractory Hypoxemia,Cardiogenic Shock,Septic Shock,Extracorporeal Membrane Oxygenation","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,150
NCT04438070,Recruiting,"April 10, 2020",June 2020,COVID-19,"Randomized,Parallel Assignment,Cluster randomized multi-center trial,Screening,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04511780,Not yet recruiting,September 2020,September 2021,"Critical Illness,Covid19,Stress Disorders, Post-Traumatic","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,5000
NCT04485169,Completed,"April 1, 2020","July 31, 2020","COVID-19,Cytokine Release Syndrome","Non-Randomized,Parallel Assignment,It was an interventional retrospective Propensity score matched (PSM) single centre based cohort study in Pak Emirates Military Hospital Rawalpindi (PEMH), Pakistan from 1st April to 30th June 2020. This study was carried out at the Department of Pulmonology and Critical care. PEMH is the largest Covid-19 designated hospital in the country. Data of all hospitalized patients is maintained by PEMH Covid-19 Research and evaluation cell. The study was approved by Institutional Review Board.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,280
NCT04444596,Recruiting,"June 17, 2020","March 31, 2021","COVID-19,SARS-CoV 2","N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04407429,Recruiting,"May 27, 2020","June 27, 2021","SARS-CoV-2,COVID-19","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,12000
NCT04422691,Recruiting,"July 1, 2020",December 2025,"COVID-19,Pneumonia, Viral,Pulmonary Infection","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:17 Years,Max Age:N/A",No,200
NCT04346589,Recruiting,"April 15, 2020",August 2020,"Pneumonia, Ventilator-Associated,Coronavirus Infection","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,10
NCT04399317,Recruiting,"May 28, 2020",August 2020,ARDS Associated With COVID-19,"Randomized,Factorial Assignment,randomization to treatment or control group,Treatment,Double (Participant, Outcomes Assessor),Due to the technical facts (use of a different mechanical ventilator) only the participants (who are sedated) and the outcome assessor will be blinded for the treatment arm.","gender:All,Min Age:18 Years,Max Age:99 Years",No,20
NCT04407260,Completed,"March 6, 2020","May 1, 2020","COVID -19,Respiratory Failure,Hypoxia","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,136
NCT04572360,Not yet recruiting,"October 1, 2020","June 30, 2023",Coronavirus Disease (COVID-19),"Randomized,Parallel Assignment,A triple-blinded, randomized, parallel groups, controlled clinical trial. A total of 172 eligible patients will be randomized 1:1:1:1 into four groups: cardiorespiratory exercise plus Chinese herbal medicines group, cardiorespiratory exercise group, Chinese herbal medicines group and waiting list group for 12-week (3 months) with 12-week follow-up period.,Treatment,Triple (Participant, Investigator, Outcomes Assessor),Both patients and investigators will be blinded to the assigned groups. Patients will be allocated at a ratio of 1:1:1:1, the randomization will be carried out by Statistical Analysis System 9.3 (SAS 9.3) statistical software. (Descript how the blinding works here) One copy of the blind codes will be held by the project responsible unit. The statistician will be blinded throughout the study.","gender:All,Min Age:18 Years,Max Age:N/A",No,172
NCT04464460,Not yet recruiting,"September 25, 2020","October 30, 2020",Coronavirus Disease,"Randomized,Sequential Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:75 Years",No,40
NCT04511949,Recruiting,"July 12, 2020","November 30, 2020",Coronavirus Infection,"N/A,Single Group Assignment,This is a cross-sectional, single-center study carried out on the cohort of index patients followed on an outpatient basis,Other,None (Open Label)","gender:All,Min Age:3 Years,Max Age:N/A",No,500
NCT04331613,Recruiting,"January 27, 2020",December 2020,"COVID-19,Acute Respiratory Distress Syndrome,Virus; Pneumonia,Acute Lung Injury","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,9
NCT04363840,Not yet recruiting,May 2020,December 2020,"COVID,Vitamin D Deficiency,Coagulopathy,Disseminated Intravascular Coagulation","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,1080
NCT04472572,Available,N/A,N/A,N/A,N/A,"gender:All,Min Age:18 Years,Max Age:N/A",N/A,N/A
NCT04312009,Recruiting,"April 13, 2020","April 1, 2021","Corona Virus Infection,Acute Respiratory Distress Syndrome,SARS-CoV Infection","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04527198,Not yet recruiting,September 2020,June 2021,COVID-19,"N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04329546,Recruiting,"March 27, 2020","March 31, 2022",SARS-CoV-2 Viral Kinetics and Host Immune Responses,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,250
NCT04447131,Recruiting,"April 29, 2020","December 30, 2020","COVID-19,SARS-CoV-2","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04415086,Recruiting,"June 1, 2020","May 22, 2022",COVID-19,"Randomized,Parallel Assignment,1:1:1 into 3 treatment groups: A- standard (control); B- standard and convalescent plasma in a volume of 200ml (150-300ml); C- standard and convalescent plasma in a volume of 400ml (300-600ml),Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04334928,Recruiting,"April 15, 2020","December 31, 2020",Coronavirus Infection,"Randomized,Parallel Assignment,Prevention,Double (Participant, Investigator),Randomized double-blind clinical trial","gender:All,Min Age:18 Years,Max Age:70 Years",No,4000
NCT04342221,Recruiting,"March 29, 2020",February 2022,"COVID-19, Hydroxychloroquine Sulfate","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:99 Years",No,220
NCT04352946,Not yet recruiting,"April 24, 2020","August 24, 2020","Prophylaxis,COVID-19,Health Care Worker,Hydroxychloroquine","Randomized,Parallel Assignment,HCW are randomized to either the study drug (HCQ) or placebo.,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Participants in the study will be randomized to either the investigational drug (HCQ) or placebo. The investigational drug and placebo will have identical appearance and be taken at the same frequency and dosage. The administration of the drug and assessment will be blinded. Study arms will be unmasked at the end of the study for the final analysis.","gender:All,Min Age:18 Years,Max Age:N/A",No,374
NCT04325919,Recruiting,"February 24, 2020","June 17, 2021",Coronavirus Infections,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,170
NCT04442958,Completed,"May 15, 2020","June 17, 2020",Acute Respiratory Distress Syndrome,"Randomized,Crossover Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:90 Years",No,60
NCT04405310,Recruiting,"May 20, 2020","December 20, 2020",SARS Pneumonia,"Randomized,Parallel Assignment,Parallel assignment, relationship 3.2.3,Treatment,Double (Participant, Care Provider),parallel design 3:2:3","gender:All,Min Age:18 Years,Max Age:70 Years",No,80
NCT04422418,Recruiting,"June 14, 2020","December 31, 2020","Cardiovascular Risk Factor,Burnout,Immune Deficiency","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04385069,Recruiting,"April 16, 2020","July 5, 2020","COV-HI,COVID-19,COVID-19 (COV) Hyperinflammatory (HI) Syndrome","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04389567,Completed,"May 12, 2020","May 25, 2020",COVID-19,"Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,10
NCT04554433,Not yet recruiting,"October 1, 2020","June 1, 2022","Covid-19,Drug Effect","Randomized,Parallel Assignment,(A) group: will receive the new protocol .
(B) group: Will receive the standard protocol .,Treatment,None (Open Label)","gender:All,Min Age:20 Years,Max Age:60 Years",No,80
NCT04290780,Recruiting,"March 9, 2020","October 30, 2020",Infection Viral,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,300
NCT04535791,Recruiting,"July 15, 2020",July 2021,"Covid19,Vitamin D","Randomized,Parallel Assignment,Blinded randomized clinical trial,Treatment,Triple (Participant, Care Provider, Investigator),To ensure that participants are unaware of the intervention they are receiving, both the capsules containing vitamin D3 and the placebo will be the same. Cholecalciferol (Vitamin D3), 4000UI tablets will be purchased from the MEDIX laboratory (trade name HISTOFIL). The placebo will consist of corn starch, which will be purchased from a supplier, who packages it in a 25 kg bag. As it is a dry product, the supplier guarantees that the corn starch maintains its characteristics for 3 years, as long as it is stored in closed container, in a cool and dry place, free of moisture, dust, insects and rodents. The encapsulation of the placebo and vitamin D3 will be carried out by an external supplier with capsules of the capsugel brand, maintaining quality control to avoid contamination of the product during storage and encapsulation. An external researcher will have a list to which group each subject belongs, without being in contact with the research.","gender:All,Min Age:18 Years,Max Age:70 Years",No,400
NCT04438629,Recruiting,"March 26, 2020","November 26, 2020","Allergy and Immunology,Infection Viral","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:90 Years",No,80
NCT04351646,Not yet recruiting,"April 15, 2020","April 15, 2022",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04483973,Not yet recruiting,August 2020,December 2020,"Covid19,Coronavirus,Coronavirus Infection,Corona Virus Infection","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04479358,Recruiting,"September 10, 2020","March 1, 2021",COVID-19,"Randomized,Parallel Assignment,Two sub-studies in parallel, each of three arms (maximum).,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,332
NCT04370171,Not yet recruiting,May 2020,December 2020,"Diabetes,Covid-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04349410,Completed,"April 11, 2020","September 14, 2020",CoVid 19 Positive,"Randomized,Factorial Assignment,Measurement of CoVid-19 pneumonia (CVP) and inflammation will be made using a patented method (FMTVDM #9566037 and adjunct USPTO submissions deemed covered by USPTO under the original patent #9566037).
Following FMTVDM measurements, patients will be randomized into one of eleven treatment arms - others may be added as information becomes available. Forty-eight to 72-hours later - providing adequate time for treatment effect - FMTVDM will be repeated.
Patients with improvement in FMTVDM will be maintained on their original treatment. FMTVDM measured treatment failure will result in a change to another arm of treatment. FMTVDM measurement showing no change will be treated by adding an additional treatment arm to patient care. Sequential FMTVDM studies will be carried out.
Simultaneous Immune and ventilatory RX. Ventilatory support per ARDS protocol. Applicable blood tests and PCR will be included.,Treatment,Single (Investigator),As FMTVDM is an absolute quantification method, which cannot be influenced by human error or bias, the final determinant of success or failure of treatment cannot be influenced. However, given the pandemic, medical, nursing, technologist and other healthcare providers will NOT be blinded to data. The availability of the data will allow real time assessment and decision making by the clinicians involved in the care of the patient.","gender:All,Min Age:N/A,Max Age:N/A",No,1800
NCT04438954,Completed,"May 5, 2020","June 18, 2020","Multiple Sclerosis,Covid-19","Case-Only,Prospective","sampling_method:Probability Sample,gender:All,Min Age:21 Years,Max Age:58 Years",No,30
NCT04471701,Recruiting,"April 13, 2020","August 31, 2020","Covid19,SARS-CoV Infection,Survey, Family Life,Epidemic Disease,Self-Assessment","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200000
NCT04392401,Recruiting,"May 11, 2020",February 2021,"Intensive Care Unit,SARS-Cov-2","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04368000,"Active, not recruiting","April 29, 2020",January 2021,"Respiratory Failure,COVID-19","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04320056,Recruiting,"April 20, 2020","October 31, 2021","Coronavirus,Pneumonia,Oxygen Toxicity","Randomized,Parallel Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,216
NCT04394442,Recruiting,"March 21, 2020",August 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,200
NCT04456010,Recruiting,"June 1, 2020","July 30, 2020","COVID19,Fertility Issues,ART","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:60 Years",No,600
NCT04313322,Recruiting,"March 16, 2020","September 30, 2020",Use of Stem Cells for COVID-19 Treatment,"N/A,Single Group Assignment,Patients positively diagnosed with COVID-19,Treatment,None (Open Label),None. This is a direct study for the potential effects of WJ-MSCs on COVID-19 outcome.","gender:All,Min Age:18 Years,Max Age:N/A",No,5
NCT04453540,Not yet recruiting,"July 1, 2020","August 30, 2020","Infectious Disease,Pneumonia,Molecular Diagnosis,Covid-19,Antibiotic Stewardship","Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,150
NCT04411511,Recruiting,"May 6, 2020","May 6, 2021","Covid-19,Obesity, Childhood,Lifestyle,Lifestyle, Healthy,Overweight, Childhood,Children, Only,Family","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:4 Years,Max Age:17 Years",No,4000
NCT04406064,Not yet recruiting,September 2020,June 2025,Viral Infection,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04354389,Withdrawn,"July 25, 2020","November 30, 2020",COVID-19,"Randomized,Sequential Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04447144,Recruiting,"June 1, 2020","September 1, 2020","Covid19,Chronic Inflammation,Non-Communicable Chronic Diseases","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,200
NCT04413045,Completed,"May 20, 2020","July 28, 2020",COVID-19,"Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,61
NCT04368338,Recruiting,"April 28, 2020","September 28, 2020","Covid-19,Lung Ultrasound,Respiratory Complication","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04459689,Recruiting,"March 15, 2020","March 31, 2022","Primary Immune Deficiency,COVID","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,200
NCT04387409,"Active, not recruiting","May 25, 2020","May 1, 2021","Infection, Respiratory Tract","Randomized,Parallel Assignment,Subjects who fulfil the inclusion/exclusion criteria will be centrally randomized in a 1:1 ratio to receive a single dose (0.1 ml) of either VPM1002 or Placebo.,Prevention,Triple (Participant, Investigator, Outcomes Assessor),The reconstitution and administration of trial intervention will be done by unblinded site personnel who will not be involved in the collection or evaluation of outcome data.","gender:All,Min Age:18 Years,Max Age:N/A",No,59
NCT04353401,Enrolling by invitation,April 2020,December 2020,"Coronavirus Infection,SARS-CoV-2","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,5000
NCT04291729,Completed,"February 17, 2020","March 19, 2020",COVID-19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,11
NCT04453670,Completed,"March 10, 2020","May 15, 2020",COVID 19,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,7
NCT04377165,Terminated,"May 6, 2020","August 26, 2020","COVID,Influenza,Gastroenteritis","Randomized,Sequential Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:90 Years",No,34
NCT04352803,Not yet recruiting,April 2020,April 2026,"Covid-19 Pneumonia,Cyotokine Storm","Non-Randomized,Sequential Assignment,This is an Interventional, Prospective, Open label (Voluntary Assignment), single to multiple center expansion, unmatched controlled, Sequentially Interim analysis tested Trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:90 Years",No,20
NCT04447235,Recruiting,"July 23, 2020",February 2021,"Cancer,COVID,Coronavirus Infection","Randomized,Parallel Assignment,Treatment,Double (Participant, Care Provider),doubled-blind and placebo-controlled","gender:All,Min Age:18 Years,Max Age:N/A",No,176
NCT04468802,Completed,"February 1, 2020","July 1, 2020","Covid19,Measles Vaccine,Mortality","Case-Only,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,32
NCT04322188,Completed,"March 19, 2020","May 8, 2020",Severe Acute Respiratory Syndrome (ARDS) Secondary to SARS-COV-2 Infection,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,220
NCT04412395,Not yet recruiting,"June 1, 2020","September 30, 2020","Corona Virus Infection,Middle East Respiratory Syndrome (MERS),Acute Respiratory Distress Syndrome,Coronavirus Infection,COVID-19,SARS-CoV 2","Randomized,Parallel Assignment,Randomized, double-blind, placebo-controlled, clinical trial.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:80 Years",No,516
NCT04326075,Suspended,October 2020,"November 9, 2020","CPAP Ventilation,COVID-19,Emergency Departments","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,900
NCT04416399,Recruiting,"July 16, 2020","December 30, 2020",Coronavirus Infection,"Randomized,Parallel Assignment,Randomised, open label parallel group controlled clinical trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,478
NCT04551690,Completed,"April 15, 2020","July 15, 2020","Pregnancy,Covid19,Labor (Obstetrics)--Complications,Demography","Case-Control,Cross-Sectional","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:45 Years",No,720
NCT04527081,"Active, not recruiting","August 31, 2020","September 30, 2021",COVID-19,"Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:20 Years,Max Age:65 Years",No,30
NCT04443764,Not yet recruiting,"June 22, 2020","July 13, 2020","Migrants,Anxiety,Depression","Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,287
NCT04366297,Completed,"January 12, 2020","February 25, 2020","Cardiac Arrest,Emergencies","Randomized,Crossover Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,41
NCT04565106,Completed,"April 15, 2020","May 31, 2020","Covid19,Hypoxemic Respiratory Failure,Hypoxemia","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,16
NCT04476680,Not yet recruiting,"September 1, 2020","April 28, 2021","SARS-CoV Infection,Vitamin D Deficiency,Covid19,Acute Respiratory Tract Infection","Randomized,Parallel Assignment,Double-blind randomized design comparing 1000 I.U. vitamin D versus matched placebo.,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Allocation by computer-generated randomisation schedule (http://www.randomization.com) The vitamin D supplement and the placebo supplement will be manufactured by Pure Encapsulations, Sudbury, Massachusetts, USA. To ensure double-blinding for the investigator and participant in situ, the active and placebo supplements will be presented as identical (size and appearance) tablets that will be indiscernible from each other.","gender:All,Min Age:18 Years,Max Age:30 Years",No,4400
NCT04395859,Recruiting,"May 27, 2020",December 2021,"Age Related Macular Degeneration,Diabetic Macular Edema,Retinal Vein Occlusion","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1500
NCT04333355,Recruiting,"May 8, 2020","April 30, 2021",COVID-19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04377035,Recruiting,"March 31, 2020","March 1, 2021",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04379037,Recruiting,"June 27, 2020","November 1, 2020",Severe Acute Respiratory Syndrome Coronavirus 2,"N/A,Single Group Assignment,The objective of this study is to determine the therapeutic effect of transcutaneous vagus nerve stimulation in patients with moderate, severe or critical pneumonia associated with Coronavirus Disease 2019 (COVID-19).,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04320732,Recruiting,"March 27, 2020","March 20, 2030",Coronavirus,"Case-Control,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,250000
NCT04360733,Recruiting,"April 20, 2020",September 2022,"SARS-CoV 2,COVID","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04465058,Recruiting,"July 8, 2020","August 10, 2020",COVID19,"Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,50
NCT04470323,Recruiting,"July 22, 2020",November 2020,T Cell Deficiency,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04515108,Completed,"March 10, 2020","August 10, 2020","Pregnancy, Infections in,Covid19","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:42 Years",No,108
NCT04473157,Recruiting,"July 1, 2020","October 30, 2020","Anosmia,Covid19,Dysgeusia","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04509947,Recruiting,"August 11, 2020","October 26, 2021",Healthy,"Randomized,Parallel Assignment,Prevention,Double (Participant, Investigator)","gender:All,Min Age:20 Years,Max Age:N/A",No,250
NCT04420273,"Active, not recruiting","July 2, 2020","December 30, 2021",Melanoma,"Randomized,Parallel Assignment,Randomized Control Clinical Trial Arm 1: SSE educational intervention with optional physician supervised non-invasive adhesive patch-based home sample collection of a concerning mole for genomic analysis Arm 2: Active control,Prevention,Triple (Care Provider, Investigator, Outcomes Assessor)","gender:Female,Min Age:18 Years,Max Age:N/A",No,1000
NCT04522466,Terminated,"April 3, 2020","May 28, 2020",Sars-CoV2,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,7
NCT04466098,Recruiting,"July 30, 2020","December 1, 2021","Acute Respiratory Distress Syndrome,ARDS (Moderate or Severe),COVID-19 Pneumonia","Randomized,Parallel Assignment,This is a randomized (2:1 ratio) placebo controlled trial.,Treatment,Triple (Participant, Care Provider, Investigator),Patients will be randomly assigned (2:1) to receive either 300 × 10^6 MSC or vehicle placebo control. Randomization will be stratified by risk (high versus standard risk based on the presence of preexisting co-morbidities), using permuted block sizes of 3. The allocation sequence will be accessed by each cell processing laboratory through ONCORE. Personnel in the cell processing laboratories are not masked to the treatment group, but patients, clinical staff, and investigators will be unaware of treatment assignment. To maintain masking of the investigators and clinicians, bags containing the study products and intravenous tubing had opaque coverings applied in the cell laboratories.","gender:All,Min Age:18 Years,Max Age:80 Years",No,30
NCT04445493,Not yet recruiting,"October 1, 2020",June 2021,"Stroke, Acute,COVID-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,250
NCT04422444,Recruiting,"June 1, 2020","June 1, 2022","COVID19,Post Intensive Care Unit Syndrome","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:90 Years",No,100
NCT04360538,Recruiting,"April 8, 2020","December 30, 2021","Critical Illness,Corona Virus Infection,Respiratory Failure,Covid-19","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04542967,Recruiting,"June 23, 2020","September 30, 2020",Severe COVID-19 Disease,"Randomized,Parallel Assignment,Treatment,Double (Care Provider, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:90 Years",No,150
NCT04350671,Enrolling by invitation,"April 15, 2020","April 24, 2020",COVID-19,"Randomized,Parallel Assignment,The present study is a randomized, double-blind, placebo-controlled, clinical trial, with the approval of the ethics committee will be conducted on patients who have a positive test confirming COVID-19 in Loghman Hakim Medical Education Center in Tehran. Patients will be randomly assigned to the two arms of the study and after completing the course of treatment and collecting and analyzing the necessary information from each patient, the results of the study will be published both on this site and in the form of an article in a reputable international journal.,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:50 Years,Max Age:N/A",No,40
NCT04405973,Recruiting,"May 19, 2020","August 31, 2020","COVID-19,SARS-CoV 2,Extracorporeal Membrane Oxygenation,ARDS","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,100
NCT04361396,Recruiting,October 2020,October 2020,Coronavirus Infection,"N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04527224,Not yet recruiting,"December 1, 2020","April 1, 2022",Covid19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:19 Years,Max Age:80 Years",No,10
NCT04353674,Recruiting,"April 28, 2020",January 2021,"COVID-19,SARS","Randomized,Sequential Assignment,Single centre, prospective, randomized controlled pilot study with approximately 40 patients to be included: 20 in the control group and 20 patients in the L-MOD-SLEDD group.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04490278,Recruiting,"September 29, 2020","July 30, 2021",Post ICU Syndrome,"N/A,Single Group Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:100 Years",No,80
NCT04341168,Not yet recruiting,April 2020,October 2020,"COVID-19,SARS-CoV-2","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,160
NCT04336462,Recruiting,"February 15, 2020","August 1, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:85 Years",No,100
NCT04423991,Completed,"March 10, 2020","June 4, 2020","COVID-19,Coronavirus,Mortality","Non-Randomized,Parallel Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,290
NCT04338945,Completed,"March 15, 2020","May 1, 2020",COVID,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,800
NCT04344327,Completed,"April 10, 2020","April 21, 2020","Infection Viral,Infection, Hospital,COVID","Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2878
NCT04508920,Recruiting,"May 15, 2019","July 15, 2021","Cardiovascular Diseases,Heart Failure","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,76
NCT04447781,Recruiting,"July 15, 2020","February 22, 2022","Coronavirus Infection,SARS-CoV 2","Randomized,Sequential Assignment,Prevention,Triple (Participant, Investigator, Outcomes Assessor),Part A: Open Label Part B: Double-blind","gender:All,Min Age:19 Years,Max Age:64 Years",No,160
NCT04320277,Not yet recruiting,"May 16, 2020","July 30, 2020",Pharmacological Action,"Non-Randomized,Crossover Assignment,Patients. All consecutive patients with mild to moderate COVID-19 infection, older than 18, Patients should present fever, cough and myalgia and weakness and radiological findings of pneumonia.
Controls. All consecutive patients with mild to moderate COVID-19 infection, older than 18, admitted during the previous 2 weeks, who were treated with antiviral and/or hydroxychloroquine.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:85 Years",No,200
NCT04527497,Recruiting,"August 1, 2020","August 31, 2021",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04558996,Recruiting,"March 1, 2020","March 31, 2021","Covid19,Pregnancy Complications,Premature Rupture of Membrane,Abruptio Placentae,Prelabor Rupture of Membranes,Stillbirth","Cohort,Prospective","sampling_method:Probability Sample,gender:Female,Min Age:18 Years,Max Age:N/A",No,3000
NCT04413747,Not yet recruiting,"August 15, 2020","September 30, 2021","Coronavirus Infection,Cytokine Storm,Mental Disorder","N/A,Single Group Assignment,Prospective cohort study based on clinical assessment. Model- based adjusted outcome via hierarchical comparison of control curves using COVID19 national epidemic data with cyber layer algorithm of population,Supportive Care,None (Open Label),identifier number (ID) without any refer to clinical assessment or to patients","gender:All,Min Age:18 Years,Max Age:75 Years",No,1000
NCT04533360,Recruiting,"September 28, 2020","December 28, 2020",Covid19,"Ecologic or Community,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,3000
NCT04356937,"Active, not recruiting","April 20, 2020","October 1, 2020",SARS-CoV 2,"Randomized,Parallel Assignment,Prospective, multi-center, randomized,double blind, placebo-controlled trial,Treatment,Double (Participant, Investigator),Subjects who meet all inclusion criteria and none of the exclusion criteria will be randomized 2:1 to tocilizumab or placebo.","gender:All,Min Age:18 Years,Max Age:85 Years",No,243
NCT04422353,Recruiting,"May 1, 2020","December 30, 2024","Parkinson Disease,Parkinson Disease 10","Non-Randomized,Parallel Assignment,Parallel Assignment,Treatment,Double (Investigator, Outcomes Assessor)","gender:All,Min Age:50 Years,Max Age:80 Years",No,60
NCT04439071,Recruiting,"July 9, 2020","January 30, 2021","Pneumonia,COVID-19,Coronavirus","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,380
NCT04470583,Not yet recruiting,July 2020,"December 2, 2021","COVID-19,2019 Novel Coronavirus Infection,COVID-19 Infection","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:60 Years",No,116
NCT04347941,Recruiting,"July 11, 2020","September 11, 2021","ARDS, Human,Mechanical Ventilation Complication,COVID19","Randomized,Parallel Assignment,Treatment,Double (Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04470869,Recruiting,"June 12, 2020","October 12, 2021",Post Traumatic Stress Disorder,"Non-Randomized,Sequential Assignment,In this study we aimed to investigated the impact of this intervention to prevent the PTSD in the relatives by comparing the PTSD prevalence in a group of relatives that loved ones were hospitalized after the confinement measure but before the OLAF intervention and a group of relatives that loved ones were hospitalized during the OLAF intervention.,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,130
NCT04422587,"Active, not recruiting","March 13, 2020",June 2021,Emergencies,"Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:15 Years,Max Age:N/A",No,1860
NCT04402827,Recruiting,"August 1, 2020","January 30, 2021","Health Care Worker Patient Transmission,Receptor Site Alteration,Susceptibility, Disease,Immune Response","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:65 Years",No,60
NCT04455243,Not yet recruiting,"August 1, 2020","August 30, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,1180
NCT04359290,Recruiting,"July 1, 2020",July 2021,"ARDS, Human,COVID","N/A,Single Group Assignment,Ruxolitinib will be administered p.o. or by gavage feeding starting with 2 x 10mg bid dose at day 1 and can be increased up to 2 x 15mg bid from day 2 to day 28 (max) (depending on platelet counts and renal function). Ruxolitinib will be administered in the morning and evening. Dosing will be adjusted according to toxicity and kidney function; open design, single arm,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,15
NCT04468139,Recruiting,"June 20, 2020","July 30, 2020",Covid-19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04432948,Recruiting,"May 15, 2020",December 2020,"Covid-19,Maternal Psychological Distress,Anesthesia","Other,Prospective","sampling_method:Probability Sample,gender:Female,Min Age:18 Years,Max Age:N/A",No,200
NCT04327531,Completed,"March 26, 2020","May 28, 2020","COVID-19,Physician-Patient Relations","Ecologic or Community,Prospective","sampling_method:Probability Sample,gender:All,Min Age:25 Years,Max Age:55 Years",No,200
NCT04509973,Recruiting,"August 27, 2020","February 17, 2022","Covid19,Hypoxia","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04558385,"Active, not recruiting","July 1, 2020","October 30, 2020",Covid19,"Case-Only,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,275
NCT04386252,Not yet recruiting,July 2020,March 2021,COVID-19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,180
NCT04445467,Recruiting,"August 1, 2020",November 2020,COVID,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,190
NCT04578158,Not yet recruiting,"October 26, 2020","April 25, 2021",COVID-19,"Randomized,Parallel Assignment,prospective, randomized, controlled, interventional,Treatment,Single (Participant),add on therapy will be performed with masked tablets","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04375124,Recruiting,"April 25, 2020","September 30, 2020",COVID-19,"Non-Randomized,Parallel Assignment,This group will receive angiotensin peptide (1-7) during their treatment at hospital.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04487977,Recruiting,"April 22, 2020","September 30, 2020",Airway Management,"Other,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,5000
NCT04479982,Recruiting,"September 24, 2020","December 31, 2020",Covid19,"Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,70
NCT04359615,Not yet recruiting,"April 20, 2020","May 5, 2020",COVID-19,"Randomized,Parallel Assignment,The present study is a randomized, double-blind, placebo-controlled, clinical trial, with the approval of the ethics committee will be conducted on patients who have a positive test confirming COVID-19 in Shahid Modarres Medical Education Center and Hospital in Tehran. Patients will be randomly assigned to the two arms of the study and after completing the course of treatment and collecting and analyzing the necessary information from each patient, the results of the study will be published both on this site and in the form of an article in a reputable international journal.,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04425863,"Active, not recruiting","May 1, 2020","August 10, 2020","Severe Acute Respiratory Syndrome,Ventilation Pneumonitis","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:5 Years,Max Age:N/A",No,100
NCT04521296,Not yet recruiting,August 2020,December 2020,Mild to Moderate COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:19 Years,Max Age:N/A",No,90
NCT04353284,Recruiting,"June 19, 2020","May 31, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,114
NCT04360356,Not yet recruiting,May 2020,December 2020,COVID-19,"Randomized,Parallel Assignment,This study will be a double blind randomized controlled parallel study,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:65 Years",No,100
NCT04441814,Enrolling by invitation,"July 23, 2019",July 2021,"COVID 19,Inflammatory Status","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:50 Years,Max Age:75 Years",No,960
NCT04503525,Recruiting,"May 25, 2020","June 30, 2021","SARS-CoV,Nutrition Disorders","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04351490,Not yet recruiting,April 2020,July 2020,SARS-CoV 2,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:60 Years,Max Age:N/A",No,3140
NCT04401644,Not yet recruiting,June 2020,December 2021,"Diagnoses Disease,Coronavirus","N/A,Single Group Assignment,within group comparison of methods of detection of virus by two test methodologies. Post hoc validation of test performance against reference set.,Diagnostic,None (Open Label),The participants and the primary care provider will be masked to the outcome of the test. The test will not be used to determine clinical care and the result of the original diagnostic test will be masked from the outcomes assessor of the novel test under investigation.","gender:All,Min Age:18 Years,Max Age:100 Years",No,250
NCT04371978,Recruiting,"October 1, 2020","September 30, 2021","COVID 19,Coronavirus,Diabetes Mellitus, Type 2,Diabetes Mellitus,Glucose Metabolism Disorders,Metabolic Disease,Endocrine System Diseases,Dipeptidyl-Peptidase IV Inhibitors,Linagliptin,Severe Acute Respiratory Syndrome Coronavirus 2,Sars-CoV2,Hypoglycemic Agents,Respiratory Tract Diseases,Incretins,Hormones","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04335201,Not yet recruiting,"April 6, 2020","December 31, 2020",Patients With COVID-19 Pneumonia Will Allow to Detect an Absolute Reduction in the Rate of Respiratory-failure,"N/A,Single Group Assignment,prospective, interventional, single-arm, multicentric, open label trial with a parallel retrospective collection of data on not treated patients from IRCCS, San Raffaele Scientific Institute institutional observational study (ClinicalTrials.gov Identifier: NCT04318366),Treatment,None (Open Label),Italian Hospital","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04335071,Recruiting,"April 26, 2020",October 2020,SARS-CoV-2 Infection,"Randomized,Parallel Assignment,A multicenter, double-blind, randomized controlled phase II trial,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),All participants and study personnel involved in patient enrolment, treatment, and follow-up will be masked to group assignment until the final report will be completed and a first interpretation of the results has been done.","gender:All,Min Age:30 Years,Max Age:80 Years",No,100
NCT04260308,Recruiting,"February 3, 2020","April 20, 2020",Virus; Pneumonia,"Case-Only,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,30000
NCT04443179,Recruiting,"April 5, 2013",December 2023,"Autism Spectrum Disorder,Attention Deficit Hyperactivity Disorder,Neurodevelopmental Conditions,COVID-19","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:16 Years,Max Age:75 Years",No,790
NCT04521010,Completed,"January 1, 2020","April 30, 2020",COVID-19 Pandemic,"Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,700
NCT04418531,Not yet recruiting,June 2020,September 2020,"Pneumonia, Viral,Corona Virus Infection","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,10
NCT04573270,Completed,"April 24, 2020","September 1, 2020","Covid19,Prophylaxis","Randomized,Single Group Assignment,This study is a randomized assignment, double-blind, placebo-controlled, multi-arm, multi-site study located at Southern California Hospitals at Culver City and Hollywood.,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04369859,Recruiting,"April 23, 2020","April 22, 2021",Pregnant Women,"Cohort,Prospective","sampling_method:Probability Sample,gender:Female,Min Age:18 Years,Max Age:N/A",No,1300
NCT04384042,Not yet recruiting,May 2020,August 2020,"SARS-CoV Infection,COVID-19,Anosmia,Dysgeusia","Case-Control,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04381988,Recruiting,"May 7, 2020",May 2021,"COVID-19,Cancer","Randomized,Parallel Assignment,This is a randomized (1:1), double-blind, placebo-controlled phase II clinical trial.,Prevention,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,132
NCT04449042,Recruiting,"April 1, 2020",December 2025,"Airway Management,COVID19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:18 Years",No,15000
NCT04359862,Recruiting,"April 16, 2020","September 16, 2020","Acute Respiratory Distress Syndrome,COVID19 Infection","Randomized,Parallel Assignment,Multicenter, national, randomized, 1:1 ratio, controlled, parallel, open study,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:99 Years",No,50
NCT04391829,Not yet recruiting,"May 12, 2020","August 31, 2020","COVID-19,Sars-CoV2,Corona Virus Infection,Semen","N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:Male,Min Age:18 Years,Max Age:50 Years",No,20
NCT04368637,Recruiting,"May 3, 2020","August 30, 2020","Acute Myocardial Infarction,Ventricular Tachycardia,Sudden Cardiac Death,Stroke, Acute","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,50
NCT04389489,Recruiting,"May 14, 2020","September 30, 2020","COVID-19,Dyspareunia,Postpartum Period","Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:45 Years",No,140
NCT04342897,"Active, not recruiting","April 20, 2020","November 30, 2020","COVID-19,Pneumonia","Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,210
NCT04447638,Completed,"March 20, 2020","June 1, 2020",Tracheostomy,"Case-Only,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:90 Years",No,24
NCT04359225,Not yet recruiting,"June 30, 2020","December 31, 2021",Telehealth,"Randomized,Crossover Assignment,Randomised controlled trial,Other,Triple (Participant, Investigator, Outcomes Assessor),Patient will be blinded to form of telemedicine. Clinician will not be blinded","gender:All,Min Age:1 Year,Max Age:95 Years",No,80
NCT04534790,Recruiting,"July 24, 2020","April 5, 2021",COVID-19 Pneumonia,"Randomized,Parallel Assignment,Treatment,Double (Participant, Care Provider)","gender:All,Min Age:18 Years,Max Age:100 Years",No,30
NCT04382768,Recruiting,"May 1, 2020",January 2021,"Coronavirus Infection,Respiratory Disease,SARS (Disease)","N/A,Single Group Assignment,This is an expanded compassionate use program for patients infected with SARS-CoV-2. All patients or their legally authorized representative must provide written informed consent and the patient will be examined to assess their eligibility. Eligible patients will receive inhalation ibuprofen ate three times a day, plus standard care, until the patient became negative, or their physician considers enough or the patient requested to stop.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04544150,Completed,"June 1, 2020","September 1, 2020",Covid19,"Case-Only,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,220
NCT04380818,Recruiting,"June 5, 2020","July 1, 2021","Pneumonia, Viral","Non-Randomized,Parallel Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:99 Years",No,106
NCT04362267,Recruiting,"June 15, 2020",September 2020,Sars-CoV2,"Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04572399,Recruiting,September 2020,December 2020,Coronavirus,"N/A,Single Group Assignment,Intubated patients with confirmed SARS-CoV-2 will receive UV light treatment to potentially reduce bacterial and viral burden.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,5
NCT04366141,Recruiting,"May 1, 2020","January 1, 2021",COVID-19,"Randomized,Parallel Assignment,This will be a prospective, open-label, randomized controlled trial in which patients will be randomly allocated to two study groups on a 1:1 basis into:
COVID-19 barrier box Intervention group: Anesthesiologists will use a COVID barrier box during intubation.
Control group: Anesthesiologists will not use a COVID barrier box during intubation. Standard intubation procedures will be followed for intubation.
A block randomization strategy, using a computer-generated sequence of random numbers, will be used. Randomization will occur preoperatively if consented patients meet the eligibility criteria and provide informed consent.,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04389463,Recruiting,"May 11, 2020","June 30, 2022",Patients Undergoing Cardiac or Thoracic Surgery,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,350
NCT04324866,Not yet recruiting,"April 1, 2020",December 2020,Coronavirus Infection,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:75 Years",No,300
NCT04347694,Recruiting,"April 11, 2020","April 11, 2021","SARS-CoV 2,Immunization; Infection","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,400
NCT04343742,Recruiting,"April 1, 2020","June 1, 2020",COVID-19,"Case-Only,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,20
NCT04369989,Enrolling by invitation,"April 14, 2020","April 14, 2021","Coronavirus,Coronavirus Infection,Corona Virus Infection,COVID,Sars-CoV2,Coronavirus as the Cause of Diseases Classified Elsewhere,SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere,COVID-19,Coronavirus Disease,Coronavirus Sars-Associated as Cause of Disease Classified Elsewhere","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04542512,Not yet recruiting,October 2020,September 2021,"Cholecystitis, Acute,Cholecystitis; Gangrenous,Cholecystitis Suppurative,Covid19","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,800
NCT04516811,Recruiting,"September 21, 2020","July 31, 2022","COVID-19,SARS-CoV-2 Infection,Severe Acute Respiratory Syndrome Coronavirus 2","Randomized,Parallel Assignment,Participant identification numbers (PIN), assigned at the screening/enrolment visit, will be used throughout the study. After signing the informed consent document, eligible participants will be randomised to one of the treatment arms, stratified by study site, age group (<=65; >65 years old) and body mass index (BMI) (<30; >=30 kg/m2). An electronic randomisation application will generate the treatment allocation. The trial Program Manager (PM), who will have no direct contact with trial participants or involvement in eligibility assessment or outcome assignment, will maintain the randomisation code.,Treatment,Triple (Participant, Care Provider, Investigator),Neither participants nor the investigators will be aware of the participant's treatment allocation until the end of the study (double blinding). Blinding will be maintained by local blood bank preparing the appropriate IP and Placebo. Unmasking procedures are detailed by SOP","gender:All,Min Age:18 Years,Max Age:N/A",No,600
NCT04494204,Recruiting,"August 7, 2020","September 30, 2020",Treatment of Covid-19 Virus Infection,"Randomized,Parallel Assignment,After obtaining the informed consent, patients will be screened by undergoing various assessments and after confirming eligibility, eligible patients will be randomized in the study and assigned either to the test group or control group with Best standard of care as per institutional practice, for 10 days treatment period. Patient will be hospitalized during the treatment period.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,100
NCT04385901,Recruiting,"May 19, 2020","April 19, 2022","SARS-CoV 2,SARS Pneumonia","Non-Randomized,Parallel Assignment,Patients receiving care through the program developed by the University of Missouri Healthcare system will, if willing, return for follow up testing and be compared against a matched group that did not receive the rehabilitative treatment to see if there are short or long term differences.,Treatment,Double (Investigator, Outcomes Assessor),Participants and care providers will know which group they are in, but data will be deidentified and blinded prior to analysis or viewing by the primary investigator","gender:All,Min Age:18 Years,Max Age:N/A",No,72
NCT04290871,Withdrawn,"March 23, 2020","March 1, 2022","Coronavirus,SARS (Severe Acute Respiratory Syndrome)","Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04347070,Recruiting,"April 1, 2017","December 1, 2022","Sars-CoV2,COVID-19","Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04350593,Recruiting,"April 22, 2020",December 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,900
NCT04377763,Recruiting,"July 15, 2020",December 2020,COVID-19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04520191,Not yet recruiting,"September 1, 2020","September 30, 2021",COVID-19 Realted Disruption in Patient With Diabetes and CKD,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:21 Years,Max Age:80 Years",No,529
NCT04435223,Completed,"April 7, 2020","May 7, 2020","COVID-19 Severe Pneumonia,Severe Pneumonia Due to Other Pathogene","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,62
NCT04405232,Recruiting,"May 25, 2020","June 25, 2021","COVID,Thrombosis,Bleeding,Anticoagulation","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,5000
NCT04499391,Not yet recruiting,"October 12, 2020",July 2022,Covid19,"Randomized,Parallel Assignment,stratified cluster randomized design,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04392531,Recruiting,"April 16, 2020",December 2020,COVID19 Infection,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,120
NCT04346927,Not yet recruiting,"August 10, 2020","November 30, 2020","Telerehabilitation,Coronavirus","Randomized,Parallel Assignment,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:70 Years",No,30
NCT04338100,Not yet recruiting,"April 6, 2020","January 29, 2021","COVID,Coronavirus Infection","Case-Only,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04545749,Recruiting,"September 25, 2020","August 31, 2021",COVID-19,"Non-Randomized,Sequential Assignment,Prevention,None (Open Label)","gender:All,Min Age:20 Years,Max Age:55 Years",No,60
NCT04409821,Not yet recruiting,June 2020,February 2022,"Posttraumatic Stress Disorder,Prolonged Grief Disorder,COVID","N/A,Single Group Assignment,Feasibility study,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04426318,Recruiting,"June 14, 2020","June 30, 2022","Anxiety,Depression,Psychological Stress,Psychological Distress,Well-being","Randomized,Parallel Assignment,Random parallel assignment,Treatment,Single (Investigator),There is no outcome assessor - all assessments will be conducted online by participants. Investigators will be blind to group assignment during data analysis. Analysis of hypotheses related to baseline characteristics, adherence and dosage cannot be blinded.","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04366232,Not yet recruiting,June 2020,"August 31, 2020",Covid-19,"Randomized,Parallel Assignment,Assignment to one of two or more groups in parallel during the study No crossover,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,54
NCT04424940,Not yet recruiting,"September 1, 2020","September 1, 2021",COVID-19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:15 Years,Max Age:75 Years",No,800
NCT04361786,"Active, not recruiting","April 1, 2020","October 30, 2020",COVID 19,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,10
NCT04399252,Recruiting,"June 24, 2020","May 25, 2022",Microbiome,"Randomized,Parallel Assignment,Basic Science,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:1 Year,Max Age:N/A",No,1000
NCT04544891,Not yet recruiting,"October 1, 2020","April 1, 2023",Covid19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04445259,Recruiting,"June 20, 2020","May 31, 2021","COVID,Acute Kidney Injury,Critical Illness","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04410263,Recruiting,"April 9, 2020","December 31, 2023","Corona Virus Infection,ARDS,Coinfection","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04523090,Recruiting,"August 27, 2020",August 2021,Covid19,"Randomized,Parallel Assignment,A single-stage, double-blinded, randomised, placebo-controlled trial.,Treatment,Triple (Participant, Care Provider, Investigator),double-blind","gender:All,Min Age:18 Years,Max Age:120 Years",No,960
NCT04426695,Recruiting,"June 10, 2020","January 25, 2021",COVID-19,"Randomized,Parallel Assignment,Phase 1/Phase 2/Phase 3,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,2970
NCT04435717,Recruiting,"May 4, 2020","August 4, 2020",Covid19,"Randomized,Single Group Assignment,Patients eligible to be included in the study will be randomized in a 1: 1: 1 ratio to receive:
TCZ 8 mg / kg (with a maximum of 800 mg) in single dose + usual treatment
TCZ 8 mg / kg in two doses at 0 and 12 hours (with a maximum of 800 mg per dose) + usual treatment
Usual / standard care treatment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,78
NCT04479163,Recruiting,"June 4, 2020","July 30, 2020",COVID,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:65 Years,Max Age:N/A",No,210
NCT04486508,Recruiting,"July 30, 2020","December 6, 2020",Covid19,"Randomized,Factorial Assignment,1:1 multicenter open-label 2x2 factorial design randomized controlled trial with allocation sequence concealment and blinded endpoint adjudication.,Treatment,Single (Outcomes Assessor),For the first hypothesis, allocation sequence concealment and blinded endpoint adjudication.
For the second hypothesis, allocation sequence concealment, double-blind medication administration, and blinded endpoint adjudication.","gender:All,Min Age:18 Years,Max Age:N/A",No,600
NCT04381962,Recruiting,"May 29, 2020","October 13, 2020",COVID-19,"Randomized,Parallel Assignment,Open label, Two-arm, Randomised Superiority Trial,Treatment,None (Open Label),This is an open-label study. However, while the study is in progress, access to tabular results by allocated treatment allocation will not be available to the research team, patients, or members of the Steering Committee (unless the DSMC advises otherwise).","gender:All,Min Age:19 Years,Max Age:N/A",No,800
NCT04479124,Completed,"March 10, 2020","July 14, 2020","Trauma,Covid19","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:50 Years",No,2000
NCT04577534,Recruiting,"August 14, 2020","December 31, 2021",Covid19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,90
NCT04350476,Withdrawn,"April 17, 2020","May 1, 2020","COVID-19,Cardiac Arrhythmias","N/A,Single Group Assignment,This is a non-randomized study. Based on clinical assessment, patients will be provided with the following home monitoring system: VitalConnect Vital Sign Patch (San Jose, California) This patch provides continuous real-time monitoring of cardiac telemetry, heart rate, respiratory rate and oxygen saturation. Duration of monitoring is typically up to 7 days.
This patch is applied to the upper left side of the chest wall, attached with a hypoallergenic adhesive material. (This device is FDA approved for this indication).,Screening,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04427358,Recruiting,"May 7, 2020",August 2020,Covid-19,"Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:70 Years,Max Age:N/A",No,100
NCT04569851,Enrolling by invitation,"January 1, 2020","October 30, 2021",COVID-19 Infection,"Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100000
NCT04313023,Recruiting,"June 9, 2020",November 2020,COVID-19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04397718,Recruiting,"July 6, 2020","December 6, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:Male,Min Age:18 Years,Max Age:85 Years",No,198
NCT04410328,Not yet recruiting,"October 1, 2020","December 15, 2021",Covid19,"Randomized,Parallel Assignment,Arm 1: Aggrenox plus standard care. Participants will receive Aggrenox (Dipyridamole ER 200mg/ Aspirin 25mg orally/enterally), 2 times daily (FDA-recommended dose) starting on the day of enrollment for a total of 2 weeks.
Arm 2: Standard care. Participants will receive standard care starting on the day of enrollment for a total of 2 weeks.
The investigators will perform a randomized, 2-arm, open-label single-site pilot study to evaluate the effect of oral Aggrenox (Dipyridamole ER 200mg/ Aspirin 25mg orally/enterally), on clinical outcomes in patients with SARS-CoV-2. In this research proposal, the investigators will randomly assign 132 consenting participants with diagnosis of SARS-CoV-2 to two treatment groups: 1) Aggrenox (Dipyridamole ER 200mg/ Aspirin 25mg orally/enterally) + standard care and 2) standard care alone. Participants will be screened, enrolled, receive treatment and followed for 28 days.,Treatment,None (Open Label)","gender:All,Min Age:19 Years,Max Age:N/A",No,132
NCT04499313,Recruiting,"August 2, 2020","November 30, 2020","Covid19,ARDS","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:20 Years,Max Age:80 Years",No,60
NCT04379453,Recruiting,"April 27, 2020","April 27, 2020",Coronary Artery Disease,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,10
NCT04384406,Completed,"April 1, 2020","May 9, 2020","Chronic Disabling,COVID-19","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,467
NCT04321811,Recruiting,"March 21, 2020","March 20, 2022",Coronavirus,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100000
NCT04435080,Completed,"March 15, 2020","June 11, 2020","COVID-19,Acute Respiratory Distress Syndrome,Rehabilitation,Intensive Care Unit Acquired Weakness,Critical Illness Polyneuromyopathy","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,35
NCT04449276,Recruiting,"June 18, 2020",August 2021,"Severe Acute Respiratory Syndrome,Coronavirus,SARS-CoV-2,COVID-19","Randomized,Sequential Assignment,Prevention,Single (Outcomes Assessor),In the initial part of the dose escalation, participants will be enrolled in sentinel groups in an open manner. In the second part, participants will be enrolled in placebo-controlled groups in an observer-blind manner.","gender:All,Min Age:18 Years,Max Age:60 Years",No,168
NCT04534673,Recruiting,"August 5, 2020","December 31, 2021",COVID-19,"Randomized,Parallel Assignment,A randomized, open label, 2 arm, pilot trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04477083,"Active, not recruiting","July 15, 2020","August 15, 2020","Covid19,Hydroxychloroquine Adverse Reaction","Randomized,Crossover Assignment,The first 20 consecutive patients (group A) will be treated by oral antibiotics, supportive treatment and inhalable hydroxychloroquine (HCQ). (In day 1, an inhaled hydroxychloroquine sulfate dose of 12 mg will be taken via nebulization three times/day (TID) as a loading dose. Then, starting from day 2, same dose of 12 mg of inhaled hydroxychloroquine will be taken twice/day (BID) as maintenance dose for 5 days. The subsequent 20 consecutive patients (group B) will receive the same treatment of group A but without inhalable hydroxychloroquine (HCQ). At day 7, all patients of both groups will be evaluated by clinical, laboratory and chest CT parameters. Patients of group B who still show no clinical, laboratory or radiological improvement will continue treatment by adding inhalable hydroxychloroquine (HCQ). for another 7 days and re-evaluated at day 14. Patients of group A who still show no significant improvement at day 7 only will be re-checked at day 14.,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04475211,Not yet recruiting,July 2020,July 2022,Sars-CoV2,"Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04356534,Completed,"April 19, 2020","July 9, 2020","SARS-CoV 2,COVID-19","Randomized,Parallel Assignment,This is a prospective, interventional and randomized open label trial involving 40 patients with COVID-19 who are in respiratory distress, with the criteria that all require oxygen therapy and have radiological evidence of pneumonia, 20 of whom will receive a transfusion of convalescent patient plasma plus routine care, compared to 20 COVID-19 patients who will receive routine care alone.,Treatment,None (Open Label)","gender:All,Min Age:21 Years,Max Age:N/A",No,40
NCT04370119,Recruiting,"April 27, 2020",May 2025,SARS-Cov-2,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,4000
NCT04349228,Withdrawn,"April 28, 2020","July 15, 2020","COVID19,Sars-CoV2,Hydroxychloroquine,Prophylaxis,Healthcare Worker","Randomized,Parallel Assignment,Arm1:Hydroxychloroquine (HCQ) (200 mg / day) for at least 2 months or until potential contamination**.
Arm2:Placebo (1 tablet/day) for at least 2 months or until potential contamination**.
** If the participant is contaminated (COVID19+), he or she will be followed up by telephone according to the study schedule.,Prevention,Single (Outcomes Assessor),As the trial is open-label and to preserve the validity of the trial, the measurement of the endpoint must be blinded by a third party (i.e., an evaluator who is not aware of the arm to which the patient has been assigned or the treatment the patient is receiving) using the PROBE (""Prospective Randomized Open Blinded Endpoint"") method.","gender:All,Min Age:18 Years,Max Age:65 Years",No,0
NCT04355507,Not yet recruiting,April 2020,July 2020,COVID-19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,10000
NCT04432766,Not yet recruiting,"October 20, 2020","August 18, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,174
NCT04418518,Recruiting,"June 24, 2020",December 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",N/A,1200
NCT04346160,Not yet recruiting,"April 14, 2020","April 30, 2020","COVID,Conjunctivitis","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,25
NCT04545008,Not yet recruiting,September 2020,August 2021,Covid19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,42
NCT04322487,Recruiting,"April 8, 2020","January 15, 2021","Coronavirus,Epidemic Disease,Pneumonia, Viral","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04377074,Completed,"March 31, 2020","April 7, 2020","Parental Stress,Depression,Anxiety","Other,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2880
NCT04522986,Not yet recruiting,September 2020,December 2021,Severe Acute Respiratory Syndrome Coronavirus 2,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:20 Years,Max Age:N/A",No,6
NCT04438239,Recruiting,"June 30, 2020","December 31, 2020",Covid-19,"Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04424771,Completed,"March 1, 2020","July 1, 2020","COVID,Post Traumatic Stress Disorder","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:70 Years",No,800
NCT04323800,Recruiting,"June 10, 2020",January 2023,"Coronavirus,Convalescence","Randomized,Parallel Assignment,1:1 ratio,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,500
NCT04430062,Completed,"May 1, 2020","May 30, 2020","General Surgery,Disease Outbreaks","Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,14
NCT04397510,Enrolling by invitation,"June 1, 2020","December 31, 2020","Covid-19,ARDS, Human,Acute Lung Injury","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04420806,"Active, not recruiting","March 14, 2020",October 2020,"Exercise,Detraining,Muscle Weakness,Muscle Atrophy","Randomized,Parallel Assignment,One exercise versus one control group,Treatment,Single (Outcomes Assessor),Outcomes assessors are unaware of participants group status and were not allowed to ask correspondingly","gender:Female,Min Age:48 Years,Max Age:60 Years",No,21
NCT04526912,Recruiting,"August 28, 2020",March 2021,Acute Lung Injury,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:80 Years",No,48
NCT04408287,Not yet recruiting,"September 15, 2020","October 31, 2021",Spinal Cord Injuries,"N/A,Single Group Assignment,The proposed study will deliver an online physical activity program to persons with SCI across Ontario through the WebEx platform at Parkwood Institute. Participants will be recruited from across Ontario through SCI rehabilitation centers and established service providers. Strategic advertising through community partners such as Spinal Cord Injury Ontario, Canadian SCI Alliance and Ontario Neurotrauma Foundation will also be conducted. Study participants will include those with a spinal cord injury that have completed rehabilitation and are living in the community. Participants must have some upper limb function permitting arm movement against gravity. All participants must have physician clearance to participate in the study.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04376775,"Active, not recruiting","May 11, 2020","December 11, 2020",Transplantation,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,3602
NCT04452682,Completed,"May 25, 2020","June 21, 2020","COVID,Critical Limb Ischemia","Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,998
NCT04518735,Completed,"April 1, 2020","June 30, 2020",Covid19,"Case-Control,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1707
NCT04325412,Recruiting,"March 23, 2020","June 23, 2021",COVID-19; Cardiovascular Diseases,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04523246,Not yet recruiting,September 2020,September 2021,"Herpes Zoster,Allergy and Immunology,Corona Virus Infection","Randomized,Parallel Assignment,Two hundred nursing home residents, both men and women, aged >65 years, who have not acquired COVID-19 (verified through a screening questionnaire and by both viral antigen and antibody testing at the screen and least one week before the first injection) will get two intramuscular injections containing either the Shingrix vaccine, and the other half, two injections containing a normal saline (comparison) approximately two months apart. Blood samples are collected before the baseline injection (day zero), 1 day after the second injection (61 days post) and 1 month following the second injection (90 days). Weekly symptom checks and monthly antibody testing around day 180- will identify residents with COVID-19 and the severity of COVID-19 symptoms.,Basic Science,Triple (Participant, Care Provider, Investigator),Blinding is done to ensure staff and residents do not modify reports or reporting of COVID symptoms and to minimize other behaviors (such as sleeping, eating habits, physical activity) that may affect their innate immune system. It will also serve to minimize any bias in the processing/analysis of samples and the interpretation of the study results.
During the conduct of the study, only three people (the statistician and 2 research nurses who will reconstitute, draw up, and administer the injections) will have knowledge of the group assignments. Participants, the staff at the nursing home, the staff collecting the COVID symptom data, and study investigators are blinded to the subject assignments.","gender:All,Min Age:65 Years,Max Age:100 Years",No,250
NCT04397848,Recruiting,"May 14, 2020","June 24, 2020","Mental Health Wellness 1,PTSD,Anxiety,Stress,Depression,COVID-19,Healthcare Workers","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1200
NCT04436484,Recruiting,"April 29, 2020","October 28, 2020",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04395105,Recruiting,"May 21, 2020","January 31, 2021","Respiratory Distress Syndrome, Adult,Covid-19","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,284
NCT04567810,Recruiting,"September 18, 2020",December 2020,Covid19,"Randomized,Sequential Assignment,Prevention,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:45 Years",No,48
NCT04482686,Not yet recruiting,September 2020,April 2021,"COVID,Covid-19,Corona Virus Infection,Coronavirus Infection,Coronavirus-19,SARS-CoV2,SARS-CoV Infection","Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:75 Years",No,300
NCT04424836,Completed,"May 15, 2020","June 5, 2020","Coronavirus Infection,Pneumonia, Viral,Acute Respiratory Failure","Case-Control,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,43
NCT04501445,Not yet recruiting,"August 20, 2020","September 15, 2021","Family Members,Post Intensive Care Unit Syndrome,Post Traumatic Stress Disorder","Randomized,Parallel Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04539821,Not yet recruiting,"October 1, 2020","June 30, 2021",Chronic Pain,"N/A,Single Group Assignment,This single-arm feasibility study will be conducted in two VA sites.,Health Services Research,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04388670,Recruiting,"February 22, 2020","August 31, 2020","COVID-19,Critical Illness","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1500
NCT04473183,Recruiting,"July 21, 2020",January 2022,"Covid19,SARS-CoV Infection,SARS-CoV-2,Corona Virus Infection","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,3000
NCT04491994,Completed,"April 10, 2020","May 31, 2020","Covid19,Progression","Randomized,Parallel Assignment,Randomization rules were designed by Dr. Wasim Alamgir together with principal investigators and implemented by an independent statistician who was not involved in data analysis. Stratified random sampling was applied to stratify all eligible patients according to age, gender and comorbidities. Computerized random number generator was used and allocation was done in 2:1 sequence. Cards with each group assignment number randomly generated by computer were placed in sequentially numbered envelopes that were opened as the patients were enrolled,Treatment,None (Open Label),Neither patients, nor investigators, nor statisticians were masked to treatment assignment. Lab staff who performed sampling for PCR, basic blood tests and other routine measurement were unaware of treatment information.","gender:All,Min Age:18 Years,Max Age:80 Years",No,540
NCT04357028,Recruiting,"July 13, 2020","November 1, 2020",Covid19,"Randomized,Parallel Assignment,Prevention,Single (Participant)","gender:All,Min Age:18 Years,Max Age:50 Years",No,200
NCT04480515,Completed,"March 11, 2020","June 30, 2020","Covid19,In-hospital Cardiac Arrest","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,5000
NCT04405102,Recruiting,"September 16, 2020","January 1, 2024",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:85 Years",No,48
NCT04501952,Recruiting,"September 18, 2020",January 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:12 Years,Max Age:N/A",Yes,1230
NCT04350086,Withdrawn,"April 20, 2020","November 20, 2020","COVID-19 Infection,Sars-cov-2,Respiratory Failure,Palliative Situation","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04317092,Recruiting,"March 19, 2020","December 19, 2022",COVID-19 Pneumonia,"N/A,Single Group Assignment,This is a multicenter, single-arm, open-label, phase 2 study. All the patients enrolled are treated with tocilizumab,Treatment,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,400
NCT04340232,Not yet recruiting,November 2020,October 2021,COVID-19,"N/A,Single Group Assignment,This is a single arm, open label, single site study. Data from participants in this study with data from other COVID-19 patients not receiving baricitinib.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:89 Years",No,80
NCT04371523,Not yet recruiting,"May 1, 2020","August 30, 2020",Corona Virus Infection,"Randomized,Parallel Assignment,Parallel two-armed, multi-centred, blinded, stratified, superiority, randomized controlled trial,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Neither the participant, nor the investigators, study coordinators, adjudicator, and data analysts will know if the subject is receiving the hydroxychloroquine or placebo.","gender:All,Min Age:18 Years,Max Age:N/A",No,1100
NCT04341688,Not yet recruiting,"August 1, 2020","March 31, 2021",Covid-19,"Randomized,Parallel Assignment,A quadruple blind randomized controlled trial followed by laboratory based analysis. Six parallel groups of participants using various gargles and nasal lavage.,Supportive Care,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Identical colored and shaped bottles containing different study drugs. This will be provided by the pharmacy services of the university hospital.","gender:All,Min Age:18 Years,Max Age:65 Years",No,50
NCT04565392,Not yet recruiting,"December 1, 2020","July 31, 2021",Covid19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,216
NCT04468893,Recruiting,"May 20, 2020","September 15, 2020","Anxiety,Depression,Sleep Disturbance","Randomized,Parallel Assignment,The study has two arms, one is the intervention group that receives the treatment in addition to a chat service and the other is the comparison group that will receive treatment without the chat service. The patients in both groups will be evaluated pre and post/treatment. The participants are assigned randomly to the intervention or comparison group.,Treatment,Single (Participant),The patients are not aware that there is an intervention group and a comparison group, the participants are not related and do not know each other. The conditions of the study are only known by the researcher, the therapists, and the Ethics Committee of ELPAC-UU Universidad de Ciencias del Comportamiento","gender:All,Min Age:18 Years,Max Age:70 Years",No,128
NCT04311398,Not yet recruiting,"May 13, 2020","December 1, 2020",COVID-19,"Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:16 Years,Max Age:100 Years",No,100
NCT04379232,Completed,"March 19, 2020","April 25, 2020","Digestive Cancer,Gynaecological Cancer,Head and Neck Cancer","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,112
NCT04508959,Recruiting,"April 15, 2020",July 2021,"Coronavirus Infection,Coronavirus,SARS-CoV-2 Infection,Covid19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1500
NCT04411576,Recruiting,"April 23, 2020","December 31, 2020",SARS-CoV 2,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:99 Years",No,40000
NCT04380961,Recruiting,"April 24, 2020","August 6, 2021",Severe or Critical Confirmed Coronavirus Disease (COVID)-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:84 Years",Yes,270
NCT04498416,Recruiting,"April 27, 2020",December 2020,Mental Health Disorder,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:17 Years",No,70
NCT04560257,Recruiting,"May 1, 2020","October 30, 2020","SARS-CoV Infection,SARS (Severe Acute Respiratory Syndrome)","N/A,Single Group Assignment,quasi- experimental,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,30
NCT04383626,Completed,"March 2, 2020","May 5, 2020",COVID,"Other,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:20 Years,Max Age:N/A",No,216
NCT04491318,Recruiting,"July 1, 2020","July 29, 2020",Hemophilia Arthropathy,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:Male,Min Age:18 Years,Max Age:65 Years",No,27
NCT04360811,Recruiting,"April 17, 2020",April 2022,Pregnancy,"Non-Randomized,Parallel Assignment,Other,None (Open Label)","gender:Female,Min Age:18 Years,Max Age:N/A",No,3600
NCT04404608,Not yet recruiting,June 2020,December 2021,Lymphopenia,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,90
NCT04382625,Not yet recruiting,October 2020,"June 1, 2022","SARS-CoV-2 Pneumonia,COVID-19","Randomized,Parallel Assignment,Single-center pragmatic randomized open-label trial of hydroxychloroquine + usual care in hospitalized adults with confirmed SARS-CoV-2 infection and acute hypoxia compared to usual care.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04516941,Not yet recruiting,"October 1, 2020","December 31, 2021","SARS-CoV Infection,COVID-19","Randomized,Factorial Assignment,2x2 factorial design,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,420
NCT04381013,Not yet recruiting,December 2020,January 2021,COVID-19,"Non-Randomized,Sequential Assignment,Device Feasibility,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,4
NCT04575558,Withdrawn,"June 30, 2020","October 30, 2020",Sars-CoV2,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04537338,Not yet recruiting,"September 14, 2020","September 14, 2022",COVID-19,"Case-Control,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:6 Months,Max Age:100 Years",No,2000
NCT04369274,Not yet recruiting,May 2020,November 2020,Respiratory Failure,"N/A,Single Group Assignment,The design is a case series with repeated measures analysis. All patients will receive the experimental treatment as well as conventional ventilation and unassisted oxygenation as observed prior to initiation of mechanical ventilation.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:65 Years",No,30
NCT04554264,Recruiting,"September 1, 2020",September 2022,"Complicated Grief,Intensive Care,Covid19","Non-Randomized,Single Group Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,160
NCT04350710,Recruiting,"March 18, 2020","December 31, 2020","Acute Respiratory Distress Syndrome,COVID","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04498273,Not yet recruiting,August 2020,March 2021,COVID-19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double-blind","gender:All,Min Age:40 Years,Max Age:79 Years",N/A,7000
NCT04550390,Recruiting,"September 15, 2020","October 15, 2020",SARS-CoV Infection,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2400
NCT04468646,Recruiting,"June 15, 2020","August 30, 2020","Neurokinin 1 Receptor, Substance P, Respiratory Illness, Inflammation, Covid-19, Coronavirus","Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:90 Years",No,100
NCT04404426,Not yet recruiting,"September 15, 2020","September 15, 2021",ARDS Secondary to COVID-19 Pneumonia,"Randomized,Parallel Assignment,Prospective, multicenter, placebo-controlled, randomized, double-blind, two-parallel study, specific enteral administration by citrulline in a subgroup of resuscitation patients admitted for ARDS secondary to COVID-19 pneumonia, at infectious risk nosocomial important because having biological stigmas of immunosuppression on admission and under invasive mechanical ventilation for a prolonged period.,Treatment,Triple (Participant, Care Provider, Investigator),Double-blind","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04542226,"Active, not recruiting","March 31, 2020",October 2020,"Infections, Coronavirus","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,81
NCT04355351,Recruiting,"May 5, 2020","October 22, 2020","New Coronavirus Disease (COVID-19), Infection With SARS-CoV-2","Non-Randomized,Parallel Assignment,Basic Science,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04367363,Recruiting,"March 8, 2020","May 31, 2020","Coronavirus,Depression,Anxiety,Stress","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:21 Years,Max Age:N/A",No,150
NCT04331574,Recruiting,"March 10, 2020","April 30, 2020","COVID-19,Hypertension,Cardiovascular Diseases","Case-Only,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:120 Years",No,2000
NCT04475185,Recruiting,"July 20, 2020",December 2020,Acute Respiratory Distress Syndrome,"Sequential Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,117
NCT04389450,Recruiting,August 2020,December 2021,"COVID,ARDS","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:40 Years,Max Age:80 Years",N/A,140
NCT04472013,Recruiting,September 2020,December 2022,COVID-19 Disease,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04406493,Recruiting,"April 28, 2020","April 28, 2021","ARDS,COVID","N/A,Single Group Assignment,COVID 19 patients are admitted to Infectious Diseases Unit, will undergo examination using lung impedance device. The first value that has been measured will be set as BASAL.
During the hospitalization each patient will undergo this examination twice a day until discharged.
Changes in impedance values during admission will be evaluated as POSITIVE AND NEGATIVE PREDICTIVE values for clinical deterioration and improvement of COVID 19 patients and as a factor which predicts mechanical ventilation The time between lung impedance started to decrease (expression of the lung fluids accumulation) and the need in mechanical ventilation will be measured.,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:95 Years",No,50
NCT04562285,Recruiting,"June 23, 2020",June 2021,Covid19,"Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04435106,Completed,"April 3, 2020","May 15, 2020",Coronavirus Infections,"Case-Control,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,23
NCT04453852,Recruiting,"June 30, 2020","July 1, 2021","Coronavirus Infection,COVID","Randomized,Parallel Assignment,Randomised controlled study,Prevention,Triple (Participant, Investigator, Outcomes Assessor),Non-blind Staff administering vaccine do not participate in any other aspects of the study. Remaining trial staff and participant are blinded","gender:All,Min Age:18 Years,Max Age:65 Years",No,40
NCT04486482,Recruiting,July 2020,March 2021,Mild-to-Moderate COVID-19,"Randomized,Parallel Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04334265,Recruiting,"April 1, 2020","December 1, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,750
NCT04368351,"Active, not recruiting","March 1, 2020","July 31, 2020","COVID,Pneumonia,Diarrhea","Case-Control,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,70
NCT04389645,Completed,"April 7, 2020","May 12, 2020",COVID-19,N/A,"sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,52
NCT04460638,Recruiting,"July 23, 2020",July 2022,SARS-CoV 2,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,600
NCT04368884,Recruiting,"April 22, 2020","July 30, 2021",Covid-19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,1000
NCT04359667,Not yet recruiting,"June 16, 2020","May 15, 2021","COVID-19,Severe Pneumonia","Case-Only,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04549376,Recruiting,"July 1, 2020","October 30, 2020",COVID19,"Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:15 Years,Max Age:90 Years",No,200
NCT04369378,Not yet recruiting,"July 13, 2020","November 30, 2020","Anxiety,Well-being","Randomized,Parallel Assignment,Randomized controlled trial: adults randomly assigned to daily use of a meditation app for 30 days or control group (no usage of meditation app).,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04476706,Available,N/A,N/A,N/A,N/A,"gender:All,Min Age:18 Years,Max Age:100 Years",No,N/A
NCT04371835,Recruiting,"August 12, 2020","December 31, 2021","HIV-infection/Aids,Coronavirus Infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1500
NCT04498286,Recruiting,"August 6, 2020","December 1, 2021",Multiple Sclerosis,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,800
NCT04400890,Recruiting,"September 12, 2020",January 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:45 Years,Max Age:N/A",No,200
NCT04389996,"Active, not recruiting","May 14, 2020","May 1, 2023",Cancer,"Cohort,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:125 Years",No,5000
NCT04273321,Completed,"February 14, 2020","April 15, 2020","COVID-19,Novel Coronavirus Pneumonia","Randomized,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,86
NCT04379336,Recruiting,"May 4, 2020","April 28, 2021","COVID-19,Sars-CoV2","Randomized,Parallel Assignment,Efficacy will be determined based on documented SARS-CoV-2 infection and incidence of hospitalization. The analysis will be an intention-to-treat analysis with estimation of hazard ratio between the two arms using a Cox proportional hazard model. Adverse events will be summarized using descriptive statistics per study arm. The analysis will be a model-based analysis of cumulative data on general health status as a function of risk factors, treatment arm and time.,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double Blinded","gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04401527,Withdrawn,"July 22, 2020","August 15, 2020","COVID-19,Acute Respiratory Distress Syndrome,Acute Respiratory Failure","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04394039,Not yet recruiting,"June 1, 2020","December 31, 2020","Stress,Anxiety","Sequential Assignment,within-subjects before/ after study,Supportive Care,None (Open Label),participants do not know the hypothesis of the study, other people cannot influence the brainwave reaction","gender:All,Min Age:21 Years,Max Age:75 Years",No,34
NCT04451694,Recruiting,"April 1, 2020","November 30, 2020",Covid-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:16 Years,Max Age:N/A",No,800
NCT04362345,Recruiting,"April 9, 2020","May 17, 2020",Covid-19,"Case-Only,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04323839,Recruiting,"March 20, 2020","March 31, 2024","Pregnancy,Coronavirus,COVID-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:13 Years,Max Age:N/A",No,2000
NCT04453475,Recruiting,"July 1, 2020","December 31, 2021","Psychosomatic Disorder,Parkinson,Psychological Distress,Psychological Stress,Psychological Disease,Psychological Disorder,Psychological Impairment,Psychological Disability,Psychological Adjustment,Psychological Adaptation,Communication,Health Care Seeking Behavior,Anxiety,Behavior, Health,Health Risk Behaviors,Healthy Lifestyle","Randomized,Parallel Assignment,The methodology uses a natural variation design within the Dr. Becker Clinical Group and in comparison to group treated at the Paracelsus clinic. The interventions consist of an online depression session as a ""flipped classroom"" and/or an online lecture with socio-medical content, which are combined in such a way that the differential effects can be evaluated. For this purpose, a control group is included that does not receive these two interventions (but receives a similar rehabilitation treatment to the intervention groups).,Health Services Research,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,1230
NCT04473053,Recruiting,"July 3, 2020","December 3, 2021",COVID-19,"Randomized,Parallel Assignment,Randomised clinical trial - currently two treatment arms and one standard of care arm,Treatment,Single (Outcomes Assessor),The biomarker analysis team will be masked to the trial treatment.","gender:All,Min Age:16 Years,Max Age:N/A",No,60
NCT04385823,Completed,"March 1, 2020","May 4, 2020","Respiratory Syndrome, Acute, Severe,Hypoxic Respiratory Failure,Viral Pneumonia","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,62
NCT04568889,Not yet recruiting,"September 28, 2020","June 30, 2021","Covid19,Infectious Disease","Randomized,Parallel Assignment,Health Services Research,Double (Participant, Care Provider)","gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04410939,Completed,"April 10, 2020","May 21, 2020","COVID-19,Asymptomatic Pregnant","Case-Crossover,Retrospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:N/A,Max Age:N/A",No,179
NCT04347408,Recruiting,"May 6, 2020","December 13, 2020","COVID,Corona Virus Infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:2 Years,Max Age:15 Years",No,1000
NCT04353336,Recruiting,"March 23, 2020","December 23, 2020","COVID-19,Coronavirus Infection","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,200
NCT04341493,Recruiting,"April 6, 2020","December 30, 2020",Coronavirus Infection,"Randomized,Parallel Assignment,In this study all patients with a COVID-19 positive result attended at the Health Institute of the State of Mexico (ISEM), will be invited to participate and offered one of two options that try to reduce the complications of this disease.,Treatment,Single (Participant),Patients won´t know whether the treatment they receive is hydroxychloroquine or nitazoxanide + hydroxychloroquine.","gender:All,Min Age:5 Years,Max Age:N/A",No,86
NCT04387214,Completed,"April 13, 2020","August 10, 2020",COVID-19,"Other,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:60 Years",No,1426
NCT04475913,"Active, not recruiting","July 11, 2018",August 2020,Edentulous Mouth,"Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:50 Years,Max Age:65 Years",No,56
NCT04369794,Recruiting,"August 10, 2020",August 2023,"COVID-19,Therapeutic Vaccine,BCG,SARS-CoV 2,Transmission","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04400279,"Active, not recruiting","June 1, 2020",November 2020,"Depressive Symptomatology,Psychological Distress,Health Behavior","Randomized,Parallel Assignment,Prevention,Double (Investigator, Outcomes Assessor),PI will be blind to the allocation to the groups. Person sending out emails to participants to complete surveys will be blind to group allocation.","gender:All,Min Age:18 Years,Max Age:64 Years",No,334
NCT04273581,Not yet recruiting,"February 18, 2020","May 30, 2020",COVID-19 Thalidomide,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04344600,Recruiting,"May 29, 2020",December 2021,Sars-CoV2,"Randomized,Parallel Assignment,Prospective, randomized, single-blind, controlled trial,Prevention,Single (Participant),Single-blinded study","gender:All,Min Age:18 Years,Max Age:80 Years",No,164
NCT04479293,Recruiting,"July 1, 2020","November 30, 2020","COVID-19,Coronavirus Disease,SARS-CoV-2","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,400
NCT04575610,Not yet recruiting,"October 10, 2020","March 31, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:75 Years",No,68
NCT04443868,Not yet recruiting,January 2021,July 2021,SARS-CoV Infection,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,50
NCT04552483,Completed,"June 8, 2020","September 5, 2020","Covid19,Coronavirus","Randomized,Parallel Assignment,Patients diagnosed with COVID-19 will be randomly divided into 2 groups: experimental and control groups.
Experimental group: 196 patients diagnosed with COVID-19 confirmed by RT-PCR will receive nitazoxanide 500mg 8/8 hs for 5 days. Control group: 196 patients diagnosed with COVID-19 confirmed by RT-PCR will receive placebo 8/8 hs for 5 days.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Patients were randomly allocated into one of the two groups: A or B. Patients received labelled medication: A or B, by the pharmacist. Patients received an identification number, so care providers, outcomes assessors and investigators did not know anything regarding the patients' groups.","gender:All,Min Age:18 Years,Max Age:N/A",No,396
NCT04359797,Enrolling by invitation,"April 27, 2020",June 2021,COVID-19,"Randomized,Parallel Assignment,This study will be performed as a pragmatic controlled clinical trial with parallel group assignment.,Supportive Care,Single (Outcomes Assessor),Patients and providers will necessarily be unblinded, but outcomes will be analyzed by a blind assessor.","gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04361448,Not yet recruiting,"April 20, 2020","May 20, 2020","Covid-19,SARS-CoV-2,Diagnosis,Polymerase Chain Reaction","N/A,Single Group Assignment,Beside the regular sampling method of 1 nasopharyngeal swab, 2 extra swabs will be taken in each volunteer. Performance of the 3 methods for laboratory diagnosis by PCR of Covid-19 will be compared.,Diagnostic,None (Open Label),Each participant get study number. Samples will be identified by the study number.","gender:All,Min Age:N/A,Max Age:N/A",No,30
NCT04432350,Not yet recruiting,"June 15, 2020","May 31, 2021","COVID,Drug Effect,Drug Interaction,Risk Reduction","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,50000
NCT04435353,Recruiting,"March 22, 2020","February 1, 2021","Respiratory Distress Syndrome,Hypoxemia","Randomized,Parallel Assignment,Prospective\retrospective study,Treatment,Single (Outcomes Assessor),Research involves single blinding (researcher statistician)","gender:All,Min Age:18 Years,Max Age:75 Years",No,200
NCT04412551,Recruiting,"May 20, 2020","December 31, 2020","Corona Virus Infection,Virus Diseases,Coronaviridae Infections","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,50
NCT04432987,Recruiting,"May 25, 2020","September 25, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04328493,Recruiting,"April 7, 2020","April 1, 2022","SARS-CoV-2 Infection,COVID-19","Randomized,Parallel Assignment,The main trial is an open label, randomised, controlled trial that will be conducted in in-patients in Ho Chi Minh City. Viet Nam. Randomization will be 1:1, stratified by study site and severity of illness, to either with or without chloroquine for 10 days. All patients will also receive a supportive care/treatment according to VN MoH's guidline for COVID-19,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,250
NCT04459286,Not yet recruiting,"September 21, 2020","March 21, 2021",Covid-19,"Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:75 Years",No,98
NCT04389658,Recruiting,"May 7, 2020",August 2020,COVID-19,"Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1000
NCT04466644,Completed,"June 8, 2020","August 25, 2020",COVID-19,"Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,340
NCT04362176,Recruiting,"April 24, 2020",April 2021,"COVID-19,Coronavirus,SARS-CoV-2","Randomized,Parallel Assignment,Eligible participants will be randomized 1:1 to convalescent plasma versus lactated Ringer's solution with multivitamins. Randomization will be completed in permuted blocks and stratified by site, gender, and age. Participants, treating clinicians and outcomes assessors will all be blinded to study group assignment. Study personnel will not be blinded to the study group assignment.,Treatment,Triple (Participant, Care Provider, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04355793,Available,N/A,N/A,N/A,N/A,"gender:All,Min Age:12 Years,Max Age:N/A",N/A,N/A
NCT04321265,Recruiting,"March 19, 2020",December 2020,"COVID-19,Elderly Patients,Critical Illness,Survival,Old Age","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:70 Years,Max Age:N/A",No,4000
NCT04323514,Recruiting,"March 13, 2020","March 13, 2021",Hospitalized Patients With Covid-19 Pneumonia,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,500
NCT04412031,Completed,"November 11, 2019","May 15, 2020",to Predict an Unfavorable Evolution of Covid-19 at the Hospital Admission of Patients,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,802
NCT04542954,Completed,"March 1, 2020","August 31, 2020","Covid19,Kidney Transplant Infection,Risk Factor, Cardiovascular,Immunosuppression,Outcome, Fatal,Graft Failure","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,104
NCT04554992,"Active, not recruiting","March 20, 2020",June 2022,Covid19,"N/A,Single Group Assignment,Given that this is a pilot study to evaluate the safety of treatment with convalescent COVID-19 plasma versus standard care in subjects with severe and/or critical COVID-19 between the cases and historical controls without predetermined data, we have proposed a convenient sample size of 700 patients (350 per group).,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,350
NCT04470297,Not yet recruiting,September 2020,March 2021,"Covid19,Lung Injury","Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:80 Years",No,100
NCT04382586,Recruiting,"July 6, 2020",April 2021,"COVID-19 Pulmonary Complications,COVID-19","Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,52
NCT04452695,Recruiting,"March 10, 2020","July 31, 2020","COVID-19,Telemedicine,Robotics,Emergencies,Emerging Infectious Disease","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04508972,Recruiting,"July 1, 2020","November 1, 2020",Covid19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04381819,Recruiting,"March 2, 2020","December 31, 2023","SARS Virus,Severe Acute Respiratory Syndrome","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04379076,Recruiting,"May 14, 2020","December 30, 2020","COVID-19,Lymphocytopenia","Randomized,Parallel Assignment,randomized controlled of treatment vs placebo,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double blind","gender:All,Min Age:25 Years,Max Age:80 Years",No,48
NCT04577378,Not yet recruiting,"October 20, 2020","November 20, 2020",Covid19,"Randomized,Sequential Assignment,Patients and method :
13- This study will performed on 45 patients tested positive for the presence of COVID-19 RNA by RT-PCR kit for RNA detection will randomly divided into 3 equal groups,Treatment,Single (Participant),Single (Participant)","gender:All,Min Age:15 Years,Max Age:80 Years",No,45
NCT04366817,Not yet recruiting,April 2020,June 2020,Post Partum Depression,"N/A,Single Group Assignment,Prevention,None (Open Label)","gender:Female,Min Age:18 Years,Max Age:N/A",No,120
NCT04388514,Recruiting,"April 8, 2020","October 8, 2020",SARS-CoV-2 Respiratory Failure,"Randomized,Parallel Assignment,The study includes 2 arms:
Arm A: Blood ozonization plus BAT (n= 45 subjects)
Arm B: Standard of Care only without Blood ozonization (n= 45 subjects)
To note that the Standard of Care are therapy with antiretroviral therapy (lopinavir/ritonavir 2 tablets every 12 hours or darunavir/cobicistat 1 tablet per day) and hidrossycloroquine 400 mg every 12 hours then first day, followed by 200 mg every 12 hours for other 4 days,Treatment,Single (Investigator),Randomization, 1:1 ratio","gender:All,Min Age:18 Years,Max Age:99 Years",No,90
NCT04474457,Recruiting,"June 11, 2020","September 30, 2020",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:15 Years,Max Age:N/A",No,1000
NCT04485130,Not yet recruiting,"September 1, 2020","September 1, 2021",Covid19,"Randomized,Parallel Assignment,This is a randomized (1:1) placebo-controlled trial of disulfiram 2000 mg/day x 3 consecutive days in 60 COVID PCR+ symptomatic (N=30 mild, N=30 moderate/severe) individuals with early (<7 days from symptom onset) COVID-19 disease.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double blind","gender:All,Min Age:18 Years,Max Age:N/A",N/A,60
NCT04537117,Completed,"April 20, 2020","May 5, 2020",COVID-19,"Other,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,202
NCT04517630,Recruiting,"June 1, 2020","September 30, 2020","Coronavirus Infection,Covid19,SARS (Severe Acute Respiratory Syndrome),AKI","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:70 Years",No,90
NCT04354766,Recruiting,"April 29, 2020",July 2020,COVID,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,10
NCT04568044,Recruiting,"September 16, 2020","July 3, 2023","COVID-19,Pregnancy Related,Influenza, Human","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:60 Years",No,96
NCT04341389,"Active, not recruiting","April 12, 2020","January 31, 2021",COVID-19,"Randomized,Crossover Assignment,Prevention,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,508
NCT04537130,Not yet recruiting,"December 1, 2020",June 2022,"Pulmonary Fibrosis,Covid19","Randomized,Parallel Assignment,The trial will enroll 40 patients to be treated with either standard of care (control arm) or IN01 vaccine (experimental arm). Patients will be randomized in a 5:3 ratio to achieve 25 patients allocated in the experimental vs 15 patients in the control arm.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04442308,Not yet recruiting,"June 22, 2020","July 13, 2020","Parenting,Anxiety,Depression,Anger","Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1440
NCT04344509,Not yet recruiting,June 2020,December 2020,Ventilator Associated Pneumonia,"Case-Control,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,10000
NCT04320017,Recruiting,"March 20, 2020","May 20, 2020","COVID-19,Myocardial Injury,Myocarditis","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:16 Years,Max Age:N/A",No,500
NCT04542980,Not yet recruiting,"September 15, 2020","December 31, 2020","SARS-CoV 2 Infection,Covid19","Case-Control,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,200
NCT04345523,Recruiting,"April 3, 2020",July 2020,COVID-19,"Randomized,Parallel Assignment,1:1 ratio for CP: Control arm. Also, approximately 140-200 CP donors.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,278
NCT04388657,Recruiting,"May 1, 2020","September 1, 2020","COVID,Embolism and Thrombosis,Pneumonia, Viral","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04501991,Completed,"March 11, 2020","June 30, 2020","Type 2 Diabetes,Metabolic Control","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:85 Years",No,114
NCT04509713,Recruiting,"July 2, 2020","October 31, 2020",Covid19,"Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:16 Years,Max Age:N/A",No,16250
NCT04516486,"Active, not recruiting","March 9, 2020","December 31, 2020","Respiratory Distress Syndrome, Adult,COVID-19","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,180
NCT04349202,Recruiting,"April 10, 2020",June 2021,"COVID-19,Coronavirus Infection,Severe Acute Respiratory Syndrome Coronavirus 2","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,56000
NCT04406389,Recruiting,October 2020,June 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,186
NCT04482712,Not yet recruiting,October 2020,October 2022,"Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS),Respiratory Failure,Sars-CoV2","Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator),This is a double-blind clinical trial","gender:All,Min Age:60 Years,Max Age:N/A",No,20
NCT04437901,Not yet recruiting,June 2020,December 2021,"COVID,Arrhythmia,Torsades de Pointe Caused by Drug,Qt Interval, Variation in,Atrioventricular Block,Atrial Fibrillation,Bradyarrhythmia,Ventricular Arrythmia","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,10000
NCT04376710,Not yet recruiting,"September 1, 2020","December 31, 2021","COVID,Surgery","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:31 Days,Max Age:18 Years",No,100
NCT04456062,Recruiting,"August 4, 2020",March 2021,Psychiatric Hospitalization,"Randomized,Parallel Assignment,Health Services Research,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04334434,Not yet recruiting,"August 20, 2020","December 31, 2020",Telerehabilitation,"Randomized,Parallel Assignment,Prevention,Single (Participant)","gender:All,Min Age:65 Years,Max Age:N/A",No,30
NCT04510012,Recruiting,"March 5, 2020","March 5, 2021","SARS-CoV Infection,Covid-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04565522,Not yet recruiting,"September 21, 2020","October 31, 2021","Covid19,Dialysis,Nurse-Patient Relations","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,5000
NCT04416139,Recruiting,"May 1, 2020","May 1, 2021",Covid 19,"Non-Randomized,Parallel Assignment,Mesenchymal Stem Cell from umbilical cord allogenic from de bank laboratory, will be applied IV to 5 patients con pneumonia bilateral due to COVID 19, complicated with acute respiratory distress syndrome. The clinical, biochemical, inflammatory and immune changes will be described and compare against historical cases treated in the Instituto Nacional de Ciencias Medicas y Nutrición Salvador Zubirán,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,10
NCT04342663,"Active, not recruiting","April 10, 2020","October 1, 2020","COVID 19,Coronavirus","Randomized,Parallel Assignment,Treatment,Triple (Participant, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,152
NCT04402203,Recruiting,May 2020,July 2020,"COVID-19,Favipiravir (Favipira)","Randomized,Parallel Assignment,Double-blind, placebo-controlled randomized control study. Randomization will be done by computerized randomization table Group A Patient (25) = Favipiravir + Standard Treatment Group B Patient (25) = Only Standard Treatment For better result sample size may be multiply on the basis of availability of COVID-19 patient in the study hospital.,Treatment,Double (Participant, Care Provider)","gender:All,Min Age:18 Years,Max Age:65 Years",No,50
NCT04545060,Recruiting,"August 27, 2020",July 2021,Covid19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,1360
NCT04334629,Recruiting,"May 26, 2020","May 25, 2021","Coronavirus,Respiratory Distress Syndrome,SARS-CoV Infection","Randomized,Parallel Assignment,Treatment,Double (Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,230
NCT04148430,Recruiting,"October 30, 2019",October 2022,"B Cell ALL,B-Cell Lymphoma,B-cell Non Hodgkin Lymphoma","Non-Randomized,Sequential Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,90
NCT04537299,Not yet recruiting,December 2020,December 2023,"Covid19,SARS-CoV Infection","Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:65 Years,Max Age:N/A",No,150
NCT04386083,Recruiting,"June 10, 2020",March 2021,Coronavirus Disease 2019,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:19 Years,Max Age:N/A",No,1342
NCT04398147,Not yet recruiting,"August 1, 2020","December 30, 2021",COVID-19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:84 Years",No,696
NCT04420741,Recruiting,"June 15, 2020","May 31, 2021","COVID-19,Respiratory Failure","Randomized,Parallel Assignment,Randomization active/placebo (1:1) parallel arms,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),The preparation will be done by an unblinded study nurse at the respective ICU´s, who will be responsible for preparing the investigational drug so that it can be administered in blinded fashion. Iloprost is a colorless fluid that is to be diluted in 0.9% saline. The infusion pump containing diluted active drug and placebo will be identical on how the fluid looks and behaves.","gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04316949,Recruiting,"March 20, 2020","May 31, 2020",SARS-CoV-2 Pneumonia,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:99 Years",No,350
NCT04374279,Not yet recruiting,November 2020,November 2021,"COVID-19,SARS-CoV 2","Randomized,Parallel Assignment,Patients will be randomized 1:1 to bicalutamide with standard of care, or standard of care alone.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04438057,Recruiting,"August 12, 2020","August 12, 2021",COVID-19,"Randomized,Parallel Assignment,Outpatient open label randomized study,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04435015,Not yet recruiting,"August 1, 2020","July 30, 2021","Coagulopathy,Cardiovascular Complication,COVID-19","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04341012,Recruiting,"September 10, 2019","December 31, 2021","Liver Diseases,Liver Cancer,COVID19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04444323,Not yet recruiting,"September 1, 2020","January 1, 2021","Telemedicine,Surgery, Plastic","N/A,Single Group Assignment,Single cohort patients seen face-to-face and then by 3D telemedicine,Other,None (Open Label),Data analysis will be masked","gender:All,Min Age:1 Year,Max Age:95 Years",No,50
NCT04513964,Not yet recruiting,"September 1, 2020","June 30, 2021","Heart Failure,Covid19","Case-Control,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04547127,Recruiting,"April 29, 2020",December 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04334252,Recruiting,"April 17, 2020","December 20, 2020",COVID 19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,5000
NCT04466982,Recruiting,"July 2, 2020",January 2022,"Olfactory Disorder,COVID19,SARS-CoV-2,Anosmia,Microsomia,Smell Disorder,Quality of Life","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:85 Years",No,90
NCT04437342,"Active, not recruiting","June 30, 2020","October 10, 2020","Postpartum Depression,Psychological Stress,Maternal Distress","Other,Prospective","sampling_method:Probability Sample,gender:Female,Min Age:18 Years,Max Age:N/A",No,300
NCT04321174,Recruiting,"April 17, 2020","March 31, 2022","Coronavirus Infections,Post-exposure Prophylaxis","Randomized,Parallel Assignment,Prevention,Single (Outcomes Assessor)","gender:All,Min Age:18 Months,Max Age:N/A",No,1220
NCT04438980,Recruiting,"May 15, 2020",February 2021,Covid-19 Pneumonia,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:75 Years",No,72
NCT04345276,Completed,"March 18, 2020","April 15, 2020",COVID-19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,10
NCT04388813,Recruiting,"May 28, 2020",March 2021,"Acute Respiratory Distress Syndrome,COVID-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1500
NCT04395456,Not yet recruiting,July 2020,March 2021,Acute Respiratory Distress Syndrome Due to SARS-CoV-2 Infection (Severe COVID19),"Randomized,Parallel Assignment,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:N/A",No,144
NCT04376879,Recruiting,"May 16, 2020",November 2020,COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,384
NCT04455958,Not yet recruiting,"November 1, 2020","November 1, 2021","Hematopoietic and Lymphoid Cell Neoplasm,Malignant Solid Neoplasm,Symptomatic COVID-19 Infection Laboratory-Confirmed","Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,75
NCT04358406,Recruiting,"July 30, 2020","October 30, 2020",Sars-CoV2,"Randomized,Single Group Assignment,Randomized, blinded, placebo controlled interventional,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Treatment blinded to all but unblinded pharmacist","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04341610,Withdrawn,"April 20, 2020","April 30, 2021",Respiratory Tract Diseases,"Randomized,Parallel Assignment,Double-blind placebo-controlled,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double-blind placebo-controlled","gender:All,Min Age:18 Years,Max Age:80 Years",No,0
NCT04358939,Recruiting,"April 27, 2020","November 24, 2021","Acute Respiratory Distress Syndrome,COVID-19","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,248
NCT04560855,Recruiting,"September 14, 2020","September 14, 2021",Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04505098,Recruiting,"August 7, 2020","February 28, 2023","Covid19,Atherosclerosis,Cardiovascular Diseases,Upper Respiratory Tract Infections","Randomized,Parallel Assignment,Pragmatic randomized clinical trial,Prevention,Single (Outcomes Assessor)","gender:All,Min Age:50 Years,Max Age:N/A",No,16500
NCT04530604,Not yet recruiting,September 2020,July 2021,"COVID,Sars-CoV2,COVID-19,Acute Respiratory Distress Syndrome","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",N/A,12
NCT04555148,Recruiting,"September 20, 2020",August 2021,Covid19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:19 Years,Max Age:N/A",No,60
NCT04508075,Recruiting,"August 10, 2020",September 2021,SARS-CoV2 Infection,"Randomized,Parallel Assignment,Subjects 18-59 years of age: Randomized, observer blind, placebo-controlled two arms parallel group, prospective intervention study, to evaluate efficacy, safety, immunogenicity SARS-CoV-2 vaccine (inactivated),Prevention,Double (Participant, Investigator),Observer blind Investigational Product and Active Comparator was masking Number of lot was masking","gender:All,Min Age:18 Years,Max Age:59 Years",No,1620
NCT04408014,Not yet recruiting,"June 1, 2020","July 30, 2020","COVID,SARS-CoV 2","Other,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:6 Months,Max Age:100 Years",No,18901
NCT04510493,Not yet recruiting,September 2020,September 2023,"Coronavirus Infection,Diabetes Mellitus, Type 2","Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,116
NCT04391400,Not yet recruiting,"June 1, 2020","June 30, 2021",SARS-CoV-2,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,500
NCT04404179,Completed,"March 27, 2020","May 2, 2020",COVID-19,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,69
NCT04470739,Recruiting,"May 30, 2020","October 30, 2020","Covid19,Thymic Hypoplasia","Non-Randomized,Parallel Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:N/A,Max Age:7 Hours",No,20
NCT04394403,Recruiting,"May 14, 2020","July 15, 2021","Stress,Stress, Psychological","Randomized,Parallel Assignment,This is a randomized trial to either immediate or delayed access to the internet guided self-help program,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04424212,Recruiting,"June 10, 2020",August 2021,Depression and Quality of Life Related to the Coronavirus Pandemic,"Randomized,Parallel Assignment,Participants will be randomly allocated to either control or intervention group. Participants in the control group will receive the same treatment once the intervention group has finished the treatment.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04370808,Not yet recruiting,June 2020,March 2021,COVID-19,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04378738,Enrolling by invitation,"May 1, 2020","May 8, 2020","Social Media,Corona Virus Infection","N/A,Single Group Assignment,a survey study of a cohort about social media awareness regarding coronavirus pandemic,Health Services Research,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,212
NCT04475601,Recruiting,"July 15, 2020","May 8, 2022","COVID-19,Corona Virus Infection","Randomized,Parallel Assignment,Prospective, randomized (2:1), open, multicentre, clinical controlled trial,Treatment,None (Open Label)","gender:All,Min Age:50 Years,Max Age:N/A",No,500
NCT04372186,"Active, not recruiting","May 14, 2020","September 19, 2020",COVID-19 Pneumonia,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,379
NCT04386512,Completed,"May 15, 2020","July 15, 2020","COVID,Lymphoma","Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,89
NCT04563676,Recruiting,"September 22, 2020",March 2021,"Covid19,TSH,Cortisol","N/A,Single Group Assignment,Screening,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04456075,Recruiting,"April 1, 2020",April 2022,"SARS-CoV2,COVID","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04401241,Completed,"February 1, 2020","May 15, 2020",Covid19,"Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,257
NCT04407221,Not yet recruiting,"June 1, 2020","May 1, 2024",Transplant Recipients,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1100
NCT04467086,Not yet recruiting,September 2020,March 2021,"Mechanical Ventilation,Sedation,Critical Illness,COVID","Randomized,Parallel Assignment,Randomized Controlled Trial with 1:1 allocation (intervention and control group),Treatment,Single (Participant),Participants will be masked to intervention versus control group allocation. Care providers (including investigators) cannot be masked due to the need to titrate propranolol and sedative doses according to patient condition in the intervention arm. Similarly, outcomes assessors will be recording the daily and total doses of propranolol received by each participant, and thus cannot be blinded.","gender:All,Min Age:19 Years,Max Age:N/A",No,108
NCT04377672,Recruiting,"May 28, 2020","May 28, 2022",Corona Virus Infection,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:1 Month,Max Age:18 Years",No,30
NCT04407598,Not yet recruiting,May 2020,June 2021,"COPD Exacerbation,COPD","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:40 Years,Max Age:N/A",No,350
NCT04410458,Enrolling by invitation,"May 31, 2020","June 12, 2020",Blood Donation,"Randomized,Parallel Assignment,Health Services Research,None (Open Label)","gender:All,Min Age:18 Years,Max Age:60 Years",No,506517
NCT04275414,Completed,"February 15, 2020","May 2, 2020",Coronavirus Infections,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,27
NCT04395300,Completed,"March 30, 2020","May 16, 2020","COVID-19,Sleep Quality,General Health","Ecologic or Community,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,143
NCT04545047,"Active, not recruiting","August 7, 2020","June 30, 2022",Novel Coronavirus Disease 2019 (COVID-19),"Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,4000
NCT04452097,Not yet recruiting,"December 1, 2020","June 30, 2021","COVID-19,ARDS,Acute Respiratory Distress Syndrome","Non-Randomized,Sequential Assignment,Eligible subjects will be divided into low, medium and high-dose groups with 3 patients/group. If there is no safety concerns for each group, the dose will be escalated from lower dose to the next higher dose.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,9
NCT04454398,Recruiting,"September 17, 2020",February 2021,Covid-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,33
NCT04450277,Completed,"April 1, 2020","May 31, 2020","COVID-19,Emergency Surgery","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,15
NCT04481516,Recruiting,"July 1, 2020","February 1, 2021",Stress,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04325061,Suspended,"April 3, 2020","October 30, 2020",Acute Respiratory Distress Syndrome Caused by COVID-19,"Randomized,Parallel Assignment,Multicenter, randomized, controlled, open-label trial involving mechanically ventilated adult patients with ARDS caused by confirmed COVID-19 infection,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04413838,Not yet recruiting,"June 15, 2020","September 15, 2021","Obesity, COVID-19 Infection","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,120
NCT04497636,Recruiting,"July 3, 2020","January 31, 2021","Anxiety,Depression,Stress, Psychological,Loneliness,Social Isolation","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1092
NCT04342169,Recruiting,"April 4, 2020",April 2023,"Coronavirus Infection,Coronavirus,Infectious Disease","Randomized,Parallel Assignment,Phase 2, prospective, placebo-controlled, parallel group, randomized trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04365738,Completed,"March 11, 2020","April 26, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Single (Investigator)","gender:All,Min Age:28 Years,Max Age:45 Years",No,270
NCT04530682,Not yet recruiting,"October 20, 2020",July 2024,Rheumatoid Arthritis,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,5000
NCT04451902,Not yet recruiting,"June 30, 2020","June 30, 2021",Rare Diseases,"Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,80
NCT04475471,Recruiting,"June 11, 2020","December 30, 2021","COVID-19,Cardiovascular Diseases","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,5200
NCT04431856,Recruiting,"May 15, 2020","November 7, 2020","Anxiety,Depression,Traumatic Stress Disorder","Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,68
NCT04359953,Recruiting,"April 25, 2020","June 1, 2021",COVID-19 Infection,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:60 Years,Max Age:N/A",No,1600
NCT04299724,Recruiting,"February 15, 2020","December 31, 2024",Treat and Prevent Covid-19 Infection,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:6 Months,Max Age:80 Years",No,100
NCT04561141,Not yet recruiting,"December 1, 2020","January 1, 2022",Covid19,"Other,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,85
NCT04421612,Recruiting,"April 2, 2020","December 31, 2021","Covid19, Anxiety, Worry","Randomized,Parallel Assignment,Group one recieve a new module every three days. Group two recive a new module every 5 days.,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04476940,Not yet recruiting,September 2020,June 2022,"Covid19,Exclusive Breastfeeding","N/A,Single Group Assignment,Pre-Test Post-test,Prevention,None (Open Label)","gender:Female,Min Age:18 Years,Max Age:45 Years",No,200
NCT04332913,Recruiting,"April 1, 2020","March 31, 2021",COVID-19 Pneumonia,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04570384,Not yet recruiting,"September 28, 2020","December 28, 2021",Acute Hypoxemic Respiratory Failure,"Randomized,Parallel Assignment,Placebo controlled and Active Drug,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double Blind Clinical Trial","gender:All,Min Age:18 Years,Max Age:65 Years",No,60
NCT04432103,Not yet recruiting,"June 19, 2020","September 30, 2020",Covid-19,"Non-Randomized,Parallel Assignment,Two groups depending on the stage of the disease according to the CDC of China classification severe and critical COVID-19 pneumonia,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,36
NCT04380896,Recruiting,"April 27, 2020","July 27, 2026",SARS-CoV-2 Infection,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04369807,Recruiting,"April 21, 2020","May 31, 2023",COVID-19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,507
NCT04458298,Recruiting,"July 1, 2020","November 10, 2020",COVID-19,"Randomized,Sequential Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,24
NCT04460014,Recruiting,"September 30, 2020","August 1, 2021","Intrusive Memories of Traumatic Event(s),Post Traumatic Stress Disorder","Randomized,Parallel Assignment,Prevention,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,164
NCT04380402,Not yet recruiting,"May 20, 2020","May 8, 2022",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:85 Years",No,300
NCT04359927,Recruiting,"April 20, 2020","August 31, 2025","Sars-CoV2,Covid19,Cardiovascular Diseases,Cardiovascular Risk Factor","Case-Control,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,10000
NCT04363736,Completed,"May 5, 2020","August 12, 2020",COVID-19 Pneumonia,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04344080,Recruiting,"April 1, 2020",February 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:90 Years",No,24
NCT04338360,Approved for marketing,N/A,N/A,N/A,N/A,"gender:All,Min Age:18 Years,Max Age:N/A",N/A,N/A
NCT04391712,Completed,"April 30, 2020","July 16, 2020",COVID-19,"Randomized,Parallel Assignment,This study will utilize a randomized parallel assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:90 Years",No,10
NCT04344210,Enrolling by invitation,"April 17, 2020","August 30, 2020","COVID,Diabetes Mellitus, Type 2,Diabetes Mellitus, Type 1","Randomized,Parallel Assignment,Patients will be randomized in two groups: G1: participants will receive a tele-intervention by a case manager weekly to discuss topics related to diabetes management and mental well-being during the quarantine period ; G2: participants will receive the usual care.,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,149
NCT03376854,Recruiting,"May 1, 2018","December 31, 2020","Respiratory Distress Syndrome, Adult,Sars-CoV2","Randomized,Parallel Assignment,Randomized (1:1) control (non-blinded) trial,Treatment,None (Open Label),Since it will be obvious to observers of the subjects whether they are in the treatment (TH+NMB) or control groups, the study is not masked but all treatments that determine outcome are protocolized.","gender:All,Min Age:18 Years,Max Age:65 Years",No,20
NCT04377308,Recruiting,"May 1, 2020","October 20, 2021","COVID-19,Cytokine Storm","Non-Randomized,Parallel Assignment,All patients who enter the study will be monitored daily for symptoms of COVID-19. Patients may choose to take fluoxetine or to have treatment as usual. Patients may also choose to have blood drawn and stored for a future analysis of cytokines.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04408456,Completed,"March 1, 2020","July 31, 2020",CoVID-19,"Non-Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,325
NCT04380532,"Active, not recruiting","May 15, 2020","June 15, 2021",Covid19,"N/A,Single Group Assignment,Healthy volunteers,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:65 Years",No,20
NCT04362150,Recruiting,"April 21, 2020","December 21, 2024",COVID,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,800
NCT04352491,Completed,"April 24, 2020","May 31, 2020",COVID 19,"Case-Only,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:75 Years",No,347
NCT04402892,Not yet recruiting,"June 1, 2020","March 1, 2021","COVID-19,SARS-CoV-2 Infection","Non-Randomized,Parallel Assignment,The recruitment of healed patients will be carried out via the Mondor and Bichat hospitals.
After information and obtaining consent at D0 :
the patients will be taken from the departments of the participating centres (35 ml of blood, 5 LITHIUM HEPARINATE tubes).
Inpatients will be drawn from the wards of the participating centres (35 ml of blood, 5 LITHIUM HEPARINATE tubes).
Inpatients will be drawn from the departments of the participating centres (35 ml of blood, 5 LITHIUM HEPARINATE tubes) at D21, then at D90 (3 months) for both groups of patients.
Patients in both groups will be collected from the departments of the participating centres (35 ml of blood, 5 LITHIUM HEPARINATE tubes) at 6 months.,Basic Science,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04404361,Recruiting,"May 22, 2020","October 31, 2021",COVID,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,358
NCT04378920,Recruiting,"April 14, 2020","December 31, 2020","COVID19,Acute Respiratory Distress Syndrome","Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,180
NCT04371406,Not yet recruiting,"May 2, 2020","September 2, 2020",Covid-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,2770
NCT04576299,"Active, not recruiting","September 1, 2020","December 15, 2020",Patient Safety,"Ecologic or Community,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,800
NCT04380519,Completed,"April 23, 2020","July 24, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:100 Years",No,372
NCT04279197,Recruiting,"April 23, 2020",December 2021,Pulmonary Fibrosis Due to COVID-19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:70 Years",No,160
NCT04378244,Not yet recruiting,"November 12, 2020","March 12, 2022","COVID-19,Cytokine Storm,Acute Respiratory Distress Syndrome","N/A,Single Group Assignment,Sequential assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:100 Years",No,18
NCT04329572,Suspended,"April 23, 2020","June 30, 2020",COVID-19,"N/A,Single Group Assignment,All patients included in the study will receive hydroxychloroquine (HCQ) 400 mg (BID/ 7 days) and azithromycin (AZT) (500 mg/ 5 days) on top of standard care. Patients that do not consent to participate or that do not fulfill eligibility criteria will be invited to participate as control group and will receive standard care only.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04346953,Not yet recruiting,"August 20, 2020","November 30, 2020",Healthy Lifestyle,"Randomized,Parallel Assignment,Prevention,Single (Participant)","gender:All,Min Age:40 Years,Max Age:60 Years",No,128
NCT04514705,Recruiting,"August 11, 2020","December 31, 2021",Coronavirus Infection,"N/A,Single Group Assignment,Exercise,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,20
NCT04395833,Completed,"April 7, 2020","May 11, 2020",Identify Emerging Health Challenges for Children With Motor Disabilities and Their Parents Facing the COVID-19 Pandemic,"Family-Based,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:18 Years",No,2500
NCT04410510,Recruiting,"September 30, 2020",June 2021,"COVID,Coronavirus Infection,SARS-CoV 2,COVID19","Randomized,Parallel Assignment,This is a randomized, double-blind, placebo-controlled study to demonstrate the efficacy and safety of P2Et (Caesalpinia spinosa extract) treatment in patients with a clinical diagnosis of Covid-19 infection when added to standard therapy.,Supportive Care,Triple (Participant, Care Provider, Investigator),100 patients will be randomized in a 1: 1 ratio (50 in each group)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04341285,Not yet recruiting,"August 1, 2020","May 1, 2022","ARDS, Human,COVID-19","Randomized,Parallel Assignment,Experimental intervention: Insertion of Extracorporal Membrane Oxygenation (ECMO) within 24 hours Control intervention: Insertion of Extracorporal Membrane Oxygenation (ECMO) as rescue therapy following failure of conventional therapy for ARDS. This conventional therapy will be standardized to reduce bias.
Duration of intervention per patient: varies, depending on severity of pulmonary compromise Follow-up per patient: 90days or until hospital discharge Accompanying measures: Serum Samples and bronchoscopy samples of patients included into the trial for secondary analysis of inflammatory parameters and potential biomarkers,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04567953,"Active, not recruiting","July 28, 2020","June 27, 2021",Covid19,"N/A,Single Group Assignment,Screening,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04502667,Recruiting,"July 15, 2020",April 2021,"Covid19,Vitamin D,Children, Only","Randomized,Parallel Assignment,Open controlled clinical trial,Treatment,None (Open Label)","gender:All,Min Age:1 Month,Max Age:17 Years",No,40
NCT04375046,Not yet recruiting,September 2020,October 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,24
NCT04379661,Recruiting,"April 3, 2020",April 2021,"MS (Multiple Sclerosis),COVID-19,Support Groups","Non-Randomized,Parallel Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,52
NCT04355533,Recruiting,"July 29, 2020",December 2022,COVID-19 Infection,"Non-Randomized,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:N/A,Max Age:17 Years",No,1920
NCT04322396,Recruiting,"April 6, 2020","March 31, 2021","Virus Diseases,Infection Viral,Corona Virus Infection","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:N/A,Max Age:N/A",No,226
NCT04407572,Completed,"April 20, 2020","June 14, 2020","COVID,Zinc Deficiency,Vitamin D Deficiency","Case-Control,Prospective","sampling_method:Probability Sample,gender:Female,Min Age:18 Years,Max Age:45 Years",No,44
NCT04354272,Not yet recruiting,"April 13, 2020","June 20, 2020","Orofacial Pain,Orofacial Edema,Dental Trauma,Oral Infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,840
NCT04373200,Recruiting,"May 25, 2020","November 25, 2020","SARS-CoV-2 Coronavirus,Acute Respiratory Distress Syndrome","Non-Randomized,Parallel Assignment,Comparative study with 3 cohorts of 25 adult patients:
Cohort A: 25 COVID-19 associated ARDS
Cohort B: 25 COVID-19 without ARDS
Cohort C: 25 ARDS from other causes,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,75
NCT04406571,Recruiting,"April 1, 2020",April 2022,Pancreatic Adenocarcinoma,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,700
NCT04531202,Recruiting,"March 2, 2020","September 30, 2021",Coronavirus Infection (COVID-19),"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04343261,Completed,"April 10, 2020","August 13, 2020","Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2),COVID,Coronavirus","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:90 Years",No,48
NCT04476953,Enrolling by invitation,"August 3, 2020",July 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,70
NCT04379440,Recruiting,"April 25, 2020","November 30, 2020",COVID-19,"Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:60 Years,Max Age:N/A",No,1500
NCT04318418,Completed,"March 23, 2020","June 30, 2020",COVID-19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,3400
NCT04521309,Recruiting,"June 19, 2020",March 2021,COVID-19,"Randomized,Sequential Assignment,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04376905,Recruiting,"April 1, 2020","September 30, 2020","COVID-19,Pneumonia,Acute Respiratory Distress Syndrome","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:99 Years",No,30
NCT04331665,Not yet recruiting,"April 20, 2020","January 31, 2021","COVID-19,Pneumonia","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:12 Years,Max Age:N/A",No,64
NCT04319172,Recruiting,"March 12, 2020",April 2021,"Transplant Recipient,Infections, Coronavirus","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:16 Years,Max Age:N/A",No,50
NCT04503447,Recruiting,"August 1, 2020",September 2020,Covid19,"Other,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,430
NCT04551911,Not yet recruiting,September 2020,April 2021,"Covid19,Coronavirus,SARS-CoV-2 Infection","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,160
NCT04519216,Recruiting,"July 31, 2020","September 30, 2021","Breastfeeding,Breastfeeding, Exclusive,Breastfeeding Jaundice,Educational Problems","Randomized,Parallel Assignment,This is a prospective cluster randomized controlled trial of a novel educational intervention in pediatric and family medicine residents during the nursery rotation. In this study, we will enroll 1st year pediatric and family medicine residents and 3rd year supervising pediatric residents on their newborn nursery 4-week rotation and randomization will occur clustered by rotation month. The educational intervention will be conducted during the first week of the rotation. Both groups will complete pre-intervention survey that collects demographic information, personal infant feeding experiences, and any breastfeeding medicine experience. All participants will be invited to complete a free online course (Lactation Support in a Telehealth Setting Course) prior to the telemedicine intervention or control group discussion with the clinical pediatrician.,Other,Single (Outcomes Assessor),Outcomes are blinded to the assessor when completing the trial data analysis.","gender:All,Min Age:18 Years,Max Age:N/A",No,39
NCT04447495,Not yet recruiting,"July 1, 2020","December 31, 2020",Coronavirus,"Case-Control,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04351503,Recruiting,"April 9, 2020",April 2022,SARS Coronavirus (SARS-CoV-2) Infection,"Other,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,10000
NCT04326309,Recruiting,"March 25, 2020","September 25, 2022","COVID-19,Coronavirus Infections,Hay Fever,Asthma,Chronic Obstructive Pulmonary Disease,Influenza,Common Cold,Respiratory Tract Infections,Healthy","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04506268,Enrolling by invitation,"September 9, 2020",November 2020,Covid19,"Randomized,Parallel Assignment,Screening,Double (Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,1200
NCT04329195,Recruiting,"April 9, 2020","August 9, 2020",History of Cardiovascular Disease Treated With RAS Blockers and With SARS-CoV-2 Infection,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,554
NCT04473105,Recruiting,"May 1, 2020","July 31, 2020",COVID19,"Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04526717,Not yet recruiting,December 2020,December 2021,Covid19,"N/A,Single Group Assignment,Classical 3+3 design to determine MTD.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,15
NCT04569344,Recruiting,"January 1, 2020","June 21, 2022","Venous Thromboembolism,Covid19","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,40000
NCT04360837,Recruiting,"May 6, 2020","June 1, 2021","COVID-19,Virus; Pneumonia,Atelectasis","N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:99 Years",No,10
NCT04347681,Recruiting,"April 18, 2020","April 11, 2021",Convalescent Plasma for COVID 19,"Non-Randomized,Parallel Assignment,experimental arm receiving convalescent plasma and parallel arm is control.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:85 Years",No,575
NCT04443712,Recruiting,"May 29, 2020","December 1, 2021",Coronavirus Disease 2019 (COVID19),"Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1900
NCT04376580,Enrolling by invitation,"April 30, 2020","November 30, 2020",COVID 19,"Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04318015,Recruiting,"April 14, 2020","March 31, 2021","COVID-19,Severe Acute Respiratory Syndrome","Randomized,Parallel Assignment,Triple blinded, randomized controlled trial,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Randomization will happen after previous assignment of recruited individual to high-risk or low-risk exposure according to he or her activities. An independent member of the team will randomly assign treatment or placebo following a computer based program. Blinding will end in case elimination criteria are met.","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04384458,Recruiting,"July 20, 2020",April 2021,Coronavirus Infections,"Randomized,Parallel Assignment,The study is a open-blind, randomised trial.,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,400
NCT04365634,Completed,"February 2, 2020","April 1, 2020",COVID-19,"Case-Control,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,306
NCT04502368,Recruiting,"August 6, 2020","September 30, 2020","Fiberoptic Bronchoscopy (FOB),Bronchoalveolar Lavage (BAL),Respiratory Disease","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,15
NCT04409496,"Active, not recruiting","June 2, 2020","June 30, 2021",Smoking Cessation,"Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,108
NCT04392115,Not yet recruiting,"June 15, 2020","September 15, 2021","Comorbidities and Coexisting Conditions,Social Isolation","Randomized,Parallel Assignment,Health Services Research,Single (Outcomes Assessor)","gender:All,Min Age:65 Years,Max Age:N/A",No,372
NCT04486404,Enrolling by invitation,"April 1, 2020","November 30, 2020",Acute Stress Disorder,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2500
NCT04382053,Recruiting,"May 27, 2020","December 21, 2020","COVID 19 Pneumonia, Impaired Respiratory Function","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,120
NCT04410549,Recruiting,"June 1, 2020","December 31, 2020","Covid19,Pulmonary Embolism","N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,10
NCT04445506,Completed,"April 1, 2020","May 31, 2020","Corticosteroids,Covid19,SARS-CoV 2,Steroids,Dexamethasone","Case-Control,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04443361,Not yet recruiting,"June 22, 2020","July 13, 2020","Insomnia,Metacognitive Beliefs,Anxiety,Depression,Sleep","Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,5000
NCT04550403,Recruiting,"July 30, 2020","December 31, 2020","Diabetes Mellitus,Covid19","Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,700
NCT04434261,Recruiting,"May 11, 2020","December 31, 2020","SARS-CoV-2,Oncology,Surgery","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1500
NCT04536285,Completed,"May 1, 2020","August 31, 2020","Type 1 Diabetes,Covid19","Case-Only,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:1 Year,Max Age:18 Years",No,36
NCT04343248,Recruiting,"May 12, 2020","December 31, 2020","COVID-19,Viral Respiratory Illnesses","Randomized,Parallel Assignment,Prevention,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:55 Years,Max Age:120 Years",No,800
NCT04389671,Not yet recruiting,"June 1, 2020",November 2020,"COVID-19,Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)","N/A,Single Group Assignment,Open-label, single treatment of reconstituted lucinactant, delivered as an intratracheal liquid.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,30
NCT04422678,Not yet recruiting,June 2020,October 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04342104,Recruiting,"April 1, 2020","September 15, 2020","Respiratory Failure,Covid-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04462627,Recruiting,"April 14, 2020",December 2020,COVID 19,"Non-Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04420390,Recruiting,"May 1, 2020","September 8, 2020",Covid19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:60 Years,Max Age:N/A",No,41
NCT04427566,Recruiting,"July 23, 2020","December 31, 2021",COVID-19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,24
NCT04326725,"Active, not recruiting","March 20, 2020","September 1, 2020","Pneumonitis,Coronavirus Infection","Case-Control,Prospective","sampling_method:Probability Sample,gender:All,Min Age:20 Years,Max Age:90 Years",No,80
NCT04362813,Recruiting,"April 30, 2020","December 22, 2020",Pneumonia and Cytokine Release Syndrome (Covid-19),"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:12 Years,Max Age:N/A",N/A,450
NCT04411784,"Active, not recruiting","May 20, 2020",July 2020,"Inflammatory Bowel Diseases,COVID","Case-Control,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:16 Years,Max Age:100 Years",No,200
NCT04386070,Not yet recruiting,"May 15, 2020","May 14, 2026","Pulmonary Complications in Surgical Patients,COVID,Severe Acute Respiratory Syndrome","Randomized,Parallel Assignment,The trial uses a Bayesian adaptive platform design, allowing for termination of arms if their superiority to standard care is established, and addition of new treatment arms. Patients will be randomised 1:1:1:1 to (A) Control (normal practice; neither trial drug), (B) Lopinavir-Ritonavir only, (C) Hydroxychloroquine only, (D) both Lopinavir-Ritonavir and Hydroxychloroquine.,Prevention,None (Open Label)","gender:All,Min Age:16 Years,Max Age:N/A",No,6400
NCT04491240,Enrolling by invitation,"July 20, 2020","January 30, 2021","Covid19,SARS-CoV-2 PNEUMONIA,COVID-19","Randomized,Parallel Assignment,The trial has three groups, each with 30 subjects (n=90). All eligible study subjects will be randomized, double-blinded, to either the two treatment groups or placebo group.,Other,Double (Participant, Care Provider),Two main groups will be provided with exosomes in a specially provided solution, the third group (control) will receive the same solution without exosomes. Due to exosomes are nanoparticles and requires special methods and devices to be detected the hospital staff and patients have no way to check which group receives exosomes.","gender:All,Min Age:18 Years,Max Age:65 Years",No,90
NCT04487990,Recruiting,"June 29, 2020",July 2021,"Acute Kidney Injury,Covid19","Randomized,Parallel Assignment,Clinical trial of treatment, randomized-controlled, parallel, open, with two arms,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,90
NCT04353245,Not yet recruiting,"June 1, 2020","September 30, 2021","COVID19,Corona Virus Infection,Myocardial Injury,Pneumonia","Case-Control,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,130
NCT04497298,Recruiting,"August 10, 2020",October 2021,COVID-19,"Randomized,Parallel Assignment,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),As safety precaution, the study will begin with enrollment of two successive unblinded dose groups of sentinel participants randomized into groups of three in an open-label fashion (group A and B). All site personnel, Sponsor and participants will be unblinded.
Then remaining participants will be randomized in a blinded manner to one of three cohorts (A, B, C) and between vacccine candidate and placebo. Site personnel responsible for study medication handling, preparation and Administration will be unblinded, only.","gender:All,Min Age:18 Years,Max Age:55 Years",No,90
NCT04264858,Not yet recruiting,"March 17, 2020","May 31, 2020","2019-nCoV,Immunoglobulin of Cured Patients","Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,10
NCT04390503,Recruiting,May 2020,April 2021,"SARS-CoV 2,COVID-19","Randomized,Parallel Assignment,A total of 200 eligible subjects will be randomized in a 1:1 ratio to receive either convalescent plasma qualitatively positive for SARS-CoV-2 antibody (anti-SARS-CoV-2 plasma) or control (albumin 5%),Treatment,Double (Participant, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04362085,Recruiting,"May 11, 2020",December 2020,COVID-19,"Randomized,Parallel Assignment,This study is a 2-arm, parallel, pragmatic, multi-centre, open-label randomized controlled trial to determine the effect of therapeutic anticoagulation on the composite outcome of ICU admission, invasive mechanical ventilation and/or death in hospitalized patients with COVID-19.,Treatment,None (Open Label),Blinding of participants, clinical research staff, and clinicians is not possible due to the nature of the intervention. However, the biostatisticians will be blinded at the data analysis phase.","gender:All,Min Age:18 Years,Max Age:N/A",No,462
NCT04400032,Recruiting,"May 15, 2020",June 2021,"Acute Respiratory Distress Syndrome,Covid19","Non-Randomized,Sequential Assignment,This is a dose-escalating and safety trial using a 3+3+3 design to determine the safety, and maximum feasible tolerated dose (MFTD) of intravenously (IV) delivered bone marrow derived MSCs (BM-MSCs).
We will enroll up to 9 patients; each receiving repeated unit doses of BM-MSCs delivered by IV infusion on each of 3 consecutive days (24±4 hours apart) according to the following dose-escalation schedule (3 patients per dose panel): (i) Panel 1: 25 million cells/unit dose (cumulative dose: 75 million MSCs), (ii) Panel 2: 50 million cells/unit dose (cumulative dose: 150 million MSCs), (iii) Panel 3: up to 90 million cells/unit dose (cumulative dose: up to 270 million MSCs).,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,9
NCT04251767,Withdrawn,"February 5, 2020","April 30, 2020",COVID-19 Complicated With Refractory Intestinal Infections,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:14 Years,Max Age:70 Years",No,0
NCT04372043,Not yet recruiting,"April 30, 2020","September 30, 2020",Sleep Hygiene,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,1200
NCT04346147,Recruiting,"April 13, 2020",September 2020,COVID-19 Pneumonia,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,165
NCT04346667,Recruiting,"April 14, 2020","June 30, 2021","SARS-CoV-2,Coronavirus Infection,Asymptomatic Condition,COVID-19","Randomized,Parallel Assignment,Treatment,Double (Participant, Outcomes Assessor)","gender:All,Min Age:20 Years,Max Age:50 Years",No,400
NCT04335851,Completed,"April 6, 2020","June 3, 2020","Social Isolation,Physical Inactivity,Well-Being","Non-Randomized,Parallel Assignment,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:35 Years",No,68
NCT04385576,Recruiting,"May 15, 2020","December 30, 2020","COVID-19,Airway","Randomized,Crossover Assignment,Basic Science,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,30
NCT04389684,Recruiting,"May 27, 2020","July 27, 2021","Chemeotherapy,Immunotherapy,Treatment Mofidied,Coronavirus,Quality of Life","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04319211,Not yet recruiting,"March 25, 2020","July 20, 2020",Healthy People,"Case-Only,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:55 Years",No,200
NCT04565197,"Active, not recruiting","May 1, 2020","October 30, 2020",SARS-CoV Infection,"N/A,Single Group Assignment,Qausi-experimental,Treatment,None (Open Label)","gender:All,Min Age:15 Years,Max Age:80 Years",No,20
NCT04516564,Recruiting,September 2020,April 2021,Coronavirus Disease 2019 (COVID-19),"Randomized,Sequential Assignment,Other,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:55 Years",No,32
NCT04281693,Not yet recruiting,February 2020,March 2020,Novel Coronavirus Infection Pneumonia,"N/A,Single Group Assignment,Screening,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,230
NCT04510233,Not yet recruiting,September 2020,December 2020,Covid19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:60 Years",No,60
NCT04358003,Recruiting,"May 20, 2020","December 1, 2021","Respiratory Failure,ARDS","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04341480,Not yet recruiting,"April 10, 2020","July 10, 2020",Gynecological Cancer,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:80 Years",No,207
NCT04545242,Not yet recruiting,"October 7, 2020","December 30, 2023",Acute Hypoxemic Respiratory Failure,"Randomized,Parallel Assignment,Multicenter, randomized, controlled, open-label trial involving mechanically ventilated adult patients with AHRF (including ARDS) caused by confirmed bacterial or viral infections.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,980
NCT04556864,Not yet recruiting,"October 1, 2020","April 1, 2021","Covid19,Hemodynamic Instability,ARDS, Human","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,67
NCT04448769,Completed,"June 26, 2020","July 24, 2020","Coronavirus Infection,Prevalence","N/A,Single Group Assignment,A study of seroprevalence and symptom collection, or absence of symptoms, on a cluster (household) sample of the Grand Nancy Metropolitan population randomly selected.,Screening,None (Open Label)","gender:All,Min Age:5 Years,Max Age:N/A",No,2006
NCT04493307,Recruiting,"June 30, 2020",June 2021,COVID-19,"Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:3 Years,Max Age:N/A",No,100
NCT04333628,Not yet recruiting,April 2020,December 2021,COVID-19,"Randomized,Parallel Assignment,This study will compare three groups of treatment, identical of their size (by randomization table) group 1- 125mgx1 / d low dose chloroquine group for 7 days (or until the condition worsens, whichever comes first) group 2- Regular dose chloroquine dose at 500mgx2 / d for 7 days (or until the condition worsens, whichever comes first) 3. Standard treatment group.
We will monitor patients' clinical status and periodic PCR (Polymerase Chain Reaction) results from nasal and pharyngeal surfaces.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,210
NCT04384055,Enrolling by invitation,"March 21, 2020","December 31, 2020","COVID-19,Pneumonia, Viral","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04261426,Not yet recruiting,"February 10, 2020","June 30, 2020",2019-nCoV,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04351347,Recruiting,"June 16, 2020","December 1, 2030",COVID,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,300
NCT04522037,Recruiting,"June 1, 2020",February 2021,"Patients Hospitalized in the Hospices Civils of Lyon,COVID-19 Disease,Moderate to Severe Dyspnea,Without Resuscitation Objective Management","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04346212,Recruiting,"April 14, 2020",January 2021,"Oropharyngeal Dysphagia,COVID-19,Sars-CoV2,Nutrition","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,300
NCT04361604,Not yet recruiting,April 2020,October 2020,Adult Patients Living With HIV (PLWHIV) With Confirmed Infection With SARS-CoV-2 Since 1st January 2020,"Cohort,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,270
NCT04348656,Recruiting,"May 14, 2020","December 31, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:16 Years,Max Age:N/A",No,1200
NCT04329923,Recruiting,"April 9, 2020","December 1, 2021",COVID-19,"Randomized,Parallel Assignment,There are 3 cohorts. All partcipants in of each the cohorts are randomized to one of two arms,Treatment,Triple (Participant, Care Provider, Investigator),Cohorts 1 and 3 are double-blind placebo control cohorts. Cohort 2 is an open label randomized study","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04445207,Available,N/A,N/A,N/A,N/A,"gender:All,Min Age:12 Years,Max Age:N/A",N/A,N/A
NCT04357730,Recruiting,"May 14, 2020",November 2020,"Severe Acute Respiratory Syndrome,Respiratory Failure,Acute Respiratory Distress Syndrome","Randomized,Sequential Assignment,This is a Phase IIa clinical trial, open label, with a modified stepped-wedge design, testing systemic administration of fibrinolytic therapy with alteplase (tPA) versus standard of care for patients infected with COVID-19 resulting in severe respiratory failure. The design is a rapidly adaptive, pragmatic clinical trial, with 3 interim analyses and 1 final look at the data.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",N/A,60
NCT04573062,Recruiting,"October 12, 2020","December 31, 2024",Post-Coronavirus Disease 19,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04459325,Recruiting,"June 1, 2020","July 20, 2020","COVID-19,Coronavirus Disease 2019","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04374110,Recruiting,"May 5, 2020","August 24, 2021","COVID,Hypertension,Cardiovascular Diseases,Cardiovascular Risk Factor","Case-Control,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04495543,Not yet recruiting,August 2020,August 2021,"Suicidal Ideation,Suicide,Mental Health Issue,Depression","N/A,Single Group Assignment,3 month, within subjects longitudinal study, with each participant receiving an intensive, single session of the 'Brief Skills for Safer Living' intervention designed to mitigate suicide risk. All participants recruited will have experienced suicidal ideation within the past week at time of enrolment.,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,75
NCT04385108,Recruiting,"March 4, 2020","December 31, 2021",COVID-19,"Non-Randomized,Parallel Assignment,Basic Science,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,170
NCT04352556,Recruiting,"April 7, 2020","April 30, 2021","SARS-CoV-2 Infection,Hematological Malignancies","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,250
NCT04504734,Enrolling by invitation,"September 30, 2020","May 1, 2021",Covid19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double-blind, placebo controlled","gender:All,Min Age:18 Years,Max Age:80 Years",No,1000
NCT04498507,Recruiting,"April 16, 2020","September 30, 2020","Critical Illness,Family,Psychological Stress,Covid19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04539626,Not yet recruiting,"October 1, 2020","March 30, 2021",Covid-19,"Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor),The Outcome Assessor will be an external member of the Gynecology Service, which will be blinded to the intervention.","gender:All,Min Age:18 Years,Max Age:70 Years",No,60
NCT04354857,Recruiting,"March 27, 2020",November 2020,COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,454
NCT04565509,Not yet recruiting,"November 1, 2020","September 21, 2022","Covid19,Intellectual Disability,Developmental Disability,Child Development Disorder","Randomized,Single Group Assignment,A cluster randomized adaptive trial will be conducted. The first phase will randomize 6 schools to either a general message or focus/targeted message. Data analysis will occur and then the schools will be randomized to the best message strategy from phase 1 alone or best message plus and augmented message or implementation strategy.,Health Services Research,None (Open Label)","gender:All,Min Age:5 Years,Max Age:90 Years",No,2500
NCT04377477,Recruiting,"May 10, 2020","August 30, 2022",COVID-19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:50 Years,Max Age:N/A",No,30
NCT04377815,Recruiting,"April 23, 2020","December 23, 2020","COVID-19,Anosmia","Cohort,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04400058,Recruiting,"June 1, 2020","December 30, 2020",Covid-19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,208
NCT04491201,Recruiting,"July 27, 2020","September 27, 2020","COVID-19 Pandemics,Obstetrics and Gynecology,Workload,Questionnaire,National Survey,China","Cohort,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,6000
NCT04401072,Recruiting,"April 24, 2020",October 2020,Covid 19,"Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,500
NCT04476745,Not yet recruiting,"August 5, 2020","December 5, 2020",Cytokine Storm,"Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:30 Years,Max Age:66 Years",No,100
NCT04538586,Recruiting,"May 1, 2020","December 1, 2025",COVID-19 Screening,"Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:16 Years,Max Age:N/A",No,1000
NCT04385940,Not yet recruiting,June 2020,December 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:17 Years,Max Age:N/A",No,64
NCT04445610,Not yet recruiting,"July 1, 2020","November 1, 2020",Coronavirus (COVID-19),"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,60
NCT04327388,Completed,"March 28, 2020","September 2, 2020",Corona Virus Infection,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,420
NCT04364893,Recruiting,"April 9, 2020","December 1, 2020","Corona Virus Infection,COVID-19","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,700
NCT04327505,Recruiting,"June 3, 2020","December 31, 2022","SARS (Severe Acute Respiratory Syndrome),Cytokine Storm,ARDS, Human,COVID-19,Sars-CoV2,Acute Respiratory Failure","Randomized,Parallel Assignment,Randomized controlled, open label, multi-centre clinical trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:90 Years",No,200
NCT04454307,Not yet recruiting,July 2020,October 2020,COVID-19,"Randomized,Parallel Assignment,A randomized Double Blind Controlled Clinical Trial,Treatment,Double (Participant, Care Provider),A randomized Double Blind Controlled Clinical Trial","gender:All,Min Age:18 Years,Max Age:65 Years",No,100
NCT04453657,Not yet recruiting,October 2020,September 2021,"Stress, Psychological,Child Behavior,Social Competence","N/A,Single Group Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:3 Years,Max Age:99 Years",No,270
NCT04476979,Recruiting,"July 16, 2020","December 31, 2021","Coronavirus Infection,SARS (Severe Acute Respiratory Syndrome),Virus Diseases,Coronaviridae Infections,Nidovirales Infections,RNA Virus Infections,Respiratory Tract Infections,Respiratory Tract Disease","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04377490,Recruiting,"May 4, 2020",November 2020,"COVID-19,Hemostasis,Coagulation","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04422522,"Active, not recruiting","March 15, 2020","June 30, 2020","Fibromyalgia, Primary","Case-Only,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:19 Years,Max Age:N/A",No,45
NCT04302688,Completed,"December 10, 2019","March 4, 2020",Pneumonitis,"Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,669
NCT04445935,Recruiting,"June 28, 2020","March 28, 2021",Anticoagulation in COVID-19 ARDS,"Randomized,Parallel Assignment,This is a randomized controlled trial.,Supportive Care,Triple (Participant, Investigator, Outcomes Assessor),This study will be blinded to the above mentioned group. The PI is not involved in active treatment. Patients are sedated and ventilated when treatment starts and finally the outcome assessors will not be knowing the patients treatment.","gender:All,Min Age:18 Years,Max Age:99 Years",No,100
NCT04439006,Recruiting,"July 22, 2020","December 31, 2022","Aplastic Anemia,Hematopoietic and Lymphoid Cell Neoplasm,Malignant Solid Neoplasm,Monoclonal B-Cell Lymphocytosis,Monoclonal Gammopathy of Undetermined Significance,Myelodysplastic Syndrome,Symptomatic COVID-19 Infection Laboratory-Confirmed","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,72
NCT04473170,Completed,"April 4, 2020","July 14, 2020",Coronavirus Disease 2019 (COVID-19),"Randomized,Parallel Assignment,Parallel assignment involving two groups of participants:
Group A (Experimental arm): Autologous Non-Hematopoietic Peripheral Blood Stem Cells (NHPBSC) therapy as add-on COVID-19 standard care.
Group B (No investigational intervention arm): COVID-19 standard care.,Treatment,None (Open Label),None (open-label)","gender:All,Min Age:18 Years,Max Age:N/A",No,146
NCT04569383,Not yet recruiting,October 2020,May 2021,Covid19,"Non-Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:55 Years",No,30
NCT04341207,Recruiting,"April 3, 2020",April 2022,Cancer & COVID 19,"Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04345549,Completed,"February 26, 2020","March 30, 2020","Flu Like Symptom,Flu Like Illness","N/A,Single Group Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:60 Years",No,18
NCT04375748,Recruiting,"April 15, 2020","October 15, 2021",Acute Myocarditis,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,400
NCT04324047,Recruiting,"March 27, 2020","December 31, 2021",Corona Virus Infection,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04336657,Recruiting,April 2020,May 2020,COVID-19,"Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:8 Years,Max Age:80 Years",No,100
NCT04418609,Recruiting,"May 1, 2020","May 30, 2022",Neurologic Complication,"Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04358952,Recruiting,"April 4, 2020","November 4, 2020",Cardiomyopathies,"Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04345419,Recruiting,"June 16, 2020",December 2029,COVID,"Randomized,Parallel Assignment,Treatment,Single (Participant)","gender:All,Min Age:N/A,Max Age:N/A",No,120
NCT04395872,Not yet recruiting,"May 28, 2020","December 31, 2020","Covid19,Psychiatric Problem,Isolation, Social","Case-Only,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,54
NCT04353596,Recruiting,"April 15, 2020","May 15, 2022","SARS-CoV-2,COVID-19","Randomized,Parallel Assignment,open-label, randomized design,Treatment,Single (Outcomes Assessor),unmasked","gender:All,Min Age:18 Years,Max Age:N/A",No,208
NCT04379479,Not yet recruiting,May 2020,December 2020,"COVID-19,SARS-CoV-2 Infection","Randomized,Parallel Assignment,Exploratory clinical trial, prospective, longitudinal, placebo-controlled, double-blinded, in patients with symptoms of non-severe acute respiratory infection (suspected/confirmed cases of COVID-19).,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,562
NCT04387240,Not yet recruiting,December 2020,April 2021,"Covid 19 Positive,Corona Virus Infection","Randomized,Parallel Assignment,double blind controlled trial,Treatment,Triple (Participant, Care Provider, Investigator),the pharmacy will do the randomization of the labeled drug and placebo","gender:All,Min Age:18 Years,Max Age:60 Years",No,22
NCT04557605,Recruiting,"September 14, 2020","November 10, 2020",Hypoxemia,"Randomized,Crossover Assignment,Treatment,Single (Outcomes Assessor),The individual who will statistically analyze the data will be blinded to condition","gender:All,Min Age:18 Years,Max Age:N/A",No,12
NCT04456036,Not yet recruiting,"July 1, 2020","June 30, 2021",COVID-19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04487444,Recruiting,"September 10, 2020",June 2021,Covid19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,80
NCT04535063,Recruiting,"April 18, 2020","February 25, 2021",Covid19 Pneumonia,"N/A,Single Group Assignment,patients with severe COVID19 pneumonia will be recruited to a single arm therapy group with convalescent plasma from recovered patients,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04524962,Not yet recruiting,"September 15, 2020","September 25, 2022","Acute Respiratory Distress Syndrome,Covid19","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04390191,Recruiting,"May 7, 2020",May 2021,"COVID-19,COVID,Coronavirus","Randomized,Parallel Assignment,This is a prospective, single-center, parallel group, open-label, randomized clinical trial, where the study team will investigate the efficacy of continuous positive airway pressure therapy (CPAP) in COVID suspected or confirmed patients who are sent home from the emergency room with mild pneumonia or respiratory illness but who do not require hospital admission. The study team proposes a randomized controlled trial of CPAP (n=100) vs. control (n=100) in COVID-19 suspected or confirmed patients with pneumonia or respiratory illness.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04486144,Enrolling by invitation,"May 20, 2020","September 1, 2020","Covid19 Positive Patient,Covid19 Close Contact","Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04330261,Recruiting,"March 18, 2020","March 17, 2022","COVID-19,SARS-CoV-2 Infection,Pediatric ALL,Pneumonia, Viral,Pandemic Response","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:18 Years",No,12500
NCT04375410,Enrolling by invitation,"April 22, 2020","May 1, 2020","Hand Eczema,Hand Dermatitis,Covid19","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:13 Years",No,7000
NCT04426084,"Active, not recruiting","March 1, 2020","December 31, 2022",COVID-19,"Case-Control,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,22784
NCT04414267,Recruiting,"May 26, 2020","May 25, 2021","COVID-19,Virus Diseases,Corona Virus Infection,Coronary Heart Disease,Chronic Obstructive Pulmonary Disease","Randomized,Parallel Assignment,Patients vaccinated with placebo or BCG,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:50 Years,Max Age:N/A",No,900
NCT04393077,Completed,"May 10, 2020","May 20, 2020","Stress,Anxiety,Burnout, Caregiver","Randomized,Parallel Assignment,Supportive Care,Single (Participant)","gender:All,Min Age:18 Years,Max Age:65 Years",No,80
NCT04383613,Recruiting,"May 15, 2020","December 11, 2020","Covid-19,ARDS","Randomized,Parallel Assignment,This study is a multicenter, pragmatic, single-blind, 2-arm, parallel, randomized controlled trial.,Other,Single (Investigator),The study will be blinded at the level of the statistician.","gender:All,Min Age:18 Years,Max Age:N/A",No,350
NCT04361318,Not yet recruiting,May 2020,December 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Care Provider),a double blind randomized controlled parallel study","gender:All,Min Age:18 Years,Max Age:65 Years",No,100
NCT04351659,Recruiting,"April 14, 2020",August 2020,COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:21 Years,Max Age:65 Years",No,8
NCT04374045,Recruiting,"April 30, 2020",October 2020,SARS-CoV 2,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,25
NCT04343339,Completed,"April 8, 2020","September 30, 2020","Addiction, Substance,COVID-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04293887,Not yet recruiting,"March 1, 2020","June 30, 2020","COVID-19,Recombinant Human Interferon α1β","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,328
NCT04448119,Recruiting,September 2020,March 2021,"COVID-19,SARS-CoV-2","Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:65 Years,Max Age:N/A",No,760
NCT04534725,Not yet recruiting,September 2020,December 2021,"Cancer,Covid19,Respiratory Viral Infection","Randomized,Sequential Assignment,the study uses a SMART design. (sequential multiple arm randomised trial) meaning that participants can enter into the study and progress through the subsequent arms if they meet the additional eligibility criteria (for instance, pre-covid > post exposure > develop moderate infection > infection becomes severe) it is important to note that participants can enter into the study at any point and do not have to transition into the other arms,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),double blinding from central system.","gender:All,Min Age:18 Years,Max Age:N/A",No,2282
NCT04365764,Recruiting,"March 14, 2020","December 31, 2020","Covid-19,ARDS,Pneumonia","Case-Control,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,400
NCT04327804,Recruiting,"March 25, 2020","April 10, 2020",SARS-CoV Infection,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,120
NCT04357457,Recruiting,"September 3, 2020",December 2020,"Covid 19,Hypoxemic Respiratory Failure","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:75 Years",No,212
NCT04513314,Not yet recruiting,"November 1, 2020","November 1, 2021","Covid19,Hyperactive Delirium,Pneumonia, Viral","Randomized,Parallel Assignment,Treatment,Double (Participant, Outcomes Assessor),study rater/outcomes assessor and participant will be ignorant of the treatment arm pharmacist and investigator will be aware of the treatment arm","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04472052,Completed,"March 16, 2020","May 31, 2020","Perforated Appendicitis,Covid19","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:16 Years,Max Age:N/A",No,143
NCT04502056,Not yet recruiting,August 2020,September 2021,Covid19,"Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20000
NCT04346121,Recruiting,"April 28, 2020","June 28, 2020",Patient Safety,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1000
NCT04432051,Recruiting,"May 26, 2020","August 10, 2020",Ultrasonography,"Randomized,Parallel Assignment,patients will be divided into two groups, those with and without ultrasound.,Other,Triple (Participant, Care Provider, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:80 Years",No,100
NCT04517188,Not yet recruiting,"October 15, 2020","February 15, 2021",SARS-CoV-2 Infection,"N/A,Single Group Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04318444,Recruiting,"March 29, 2020",March 2022,"COVID-19,Corona Virus Infection","Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,1600
NCT04381845,Not yet recruiting,"May 10, 2020","June 25, 2020","COVID,Psychiatric Disorders","N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04526145,Not yet recruiting,"September 14, 2020","January 30, 2022","Stress, Psychological","N/A,Single Group Assignment,Health Services Research,None (Open Label)","gender:Female,Min Age:45 Years,Max Age:65 Years",No,30
NCT04292964,Completed,"March 1, 2020","March 13, 2020","SARS-CoV-2,Outcome, Fatal","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,201
NCT04516954,Enrolling by invitation,"August 1, 2020","December 30, 2020",COVID 19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,10
NCT04318314,Recruiting,"March 18, 2020","December 31, 2021","Health Care Worker Patient Transmission,Coronavirus,Coronavirus Infections,Immunological Abnormality","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04474236,Recruiting,"May 27, 2020","March 27, 2021","COVID-19,Acute Respiratory Failure,Triage,Lung Ultrasound,CT Scan","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:17 Years,Max Age:N/A",No,148
NCT04469621,"Active, not recruiting","July 17, 2020",October 2020,Corona Virus Infection,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:80 Years",No,67
NCT04401436,Recruiting,"May 22, 2020","June 30, 2022",Corona Virus Disease 2019,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,175
NCT04362137,Recruiting,"May 2, 2020","October 19, 2020",Cytokine Storm (Covid-19),"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:12 Years,Max Age:N/A",No,402
NCT03305341,"Active, not recruiting","July 18, 2020","November 28, 2020",Covid19,"N/A,Single Group Assignment,Treatment,None (Open Label),Open Label","gender:All,Min Age:22 Years,Max Age:72 Years",No,20
NCT04338802,Not yet recruiting,"April 2, 2020","August 1, 2020","COVID-19,Nintedanib,Safety,Effect of Drugs","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,96
NCT04497519,Recruiting,"September 15, 2020","November 15, 2020",Covid19,"N/A,Single Group Assignment,Healthy volunteers,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:65 Years",No,12
NCT04351802,Not yet recruiting,"April 20, 2020","January 20, 2021",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,180
NCT04366778,Recruiting,"May 1, 2020",December 2020,"Thrombosis,Covid-19,SARS-CoV 2","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,325
NCT04352933,Recruiting,"May 11, 2020",April 2021,COVID-19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double-blind","gender:All,Min Age:18 Years,Max Age:70 Years",No,1000
NCT04429477,Completed,"May 1, 2020","July 31, 2020","Intracranial Hypertension,Cerebral Circulatory Failure","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:1 Year,Max Age:N/A",No,50
NCT04378881,"Active, not recruiting","June 1, 2020","April 30, 2021","COVID,Drug Effect,Drug Interaction,Adverse Drug Event","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04398277,Recruiting,"May 1, 2020",April 2021,Psychological Stress,"Randomized,Single Group Assignment,All participants receive the intervention. There is a brief randomized manipulation for dosage in the first 7 days only then all participants receive the higher dose.,Supportive Care,Double (Participant, Investigator),Participants are randomized to dose condition without their knowledge for the first 7 days. The primary investigator is blinded to conditions.","gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04555187,"Active, not recruiting","June 8, 2020",December 2021,"Covid19,Cardiovascular Risk Factor","Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,60000
NCT04467008,Not yet recruiting,"July 15, 2020","August 15, 2020",Covid19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,113
NCT04401124,Not yet recruiting,"May 25, 2020","June 7, 2020","Gastric Cancer,Colorectal Cancer,Gastrointestinal Disease","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,500
NCT04346628,Enrolling by invitation,"July 12, 2020",July 2021,"Sars-CoV2,COVID-19","Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04361435,Not yet recruiting,"May 1, 2020","December 31, 2020","COVID-19,Physiotherapy","Randomized,Crossover Assignment,Patients will be randomized into one of the 2 arms (None-invasive oscillating device (NIOD) first or chest physiotherapy (CPT) first). Random allocation will be generated by an independent investigator in an equal number assigned to each intervention. Stratification will be applied for age (>18 years or =<18 years of age) and sites (CHUSJ and General Hospital).,Supportive Care,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,50
NCT04575038,Not yet recruiting,"October 15, 2020","February 28, 2021",COVID-19 Infection,"Randomized,Parallel Assignment,Randomized 1:1 brequinar 100 mg or placebo,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double blind","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04397939,Recruiting,"May 8, 2020",March 2022,"COVID-19,Myocardial Reperfusion Injury,Cardiovascular Diseases","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,5000
NCT04551768,Not yet recruiting,November 2020,April 2021,COVID19,"Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04394182,Recruiting,"April 21, 2020","April 21, 2021","Pneumonia, Viral,Cytokine Storm","N/A,Single Group Assignment,an experimental group will receive ultra low-dose lung radiotherapy,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:120 Years",No,15
NCT04543006,Not yet recruiting,"September 8, 2020","December 31, 2021",Covid19,"Sequential Assignment,sample of patients 6 and 12 months after the acute disease,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,170
NCT04526990,Recruiting,"September 15, 2020","January 30, 2022",COVID-19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,40000
NCT04428099,Recruiting,"January 13, 2020","July 12, 2022","Depressive Disorder, Treatment-Resistant","Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,186
NCT04412538,Recruiting,"May 15, 2020",September 2021,COVID-19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:59 Years",No,942
NCT04362189,"Active, not recruiting","June 30, 2020","October 31, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04525820,Not yet recruiting,"September 1, 2020","June 30, 2021","Covid19,Vitamin D Deficiency,Corona Virus Infection,ARDS,Coronavirus,SARS-CoV Infection","Randomized,Parallel Assignment,one group receives a single high dose of vitamin D in addition to treatment as usual (TAU) the other group receives a single dose of placebo in addition to TAU,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),The blinding is performed by the hospital pharmacy of the university hospital of Basel. They will provide us with packed and labeled study medication and placebo. They will provide us with medication packages for each patient which includes either high dose vitamin D and the standard medication or the placebo and the standard medication.","gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04471636,Recruiting,"September 18, 2020",March 2021,"Covid-19,Cardiovascular Risk Factor","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:40 Years,Max Age:59 Years",No,600
NCT04551781,Completed,"April 1, 2020","July 30, 2020",Covid19,"Randomized,Parallel Assignment,single-blinded randomized controlled trial,Treatment,Single (Outcomes Assessor),single blinded","gender:All,Min Age:18 Years,Max Age:N/A",No,450
NCT04368143,Recruiting,"April 1, 2020","December 31, 2020","COVID,SARS-CoV 2,Corona Virus Infection,RDT,B Cell","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04351295,Recruiting,"April 20, 2020","December 1, 2020",COVID,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,90
NCT04434131,Recruiting,"April 28, 2020","April 28, 2025",COVID-19,"N/A,Single Group Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04498247,Recruiting,"August 27, 2020","April 26, 2022",Coronavirus Disease (COVID-19),"Randomized,Sequential Assignment,Prevention,Triple (Participant, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,260
NCT04555954,Completed,"April 11, 2020","August 20, 2020","Health, Subjective,Healthy","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,205
NCT04485338,Not yet recruiting,"August 1, 2020","March 1, 2021",Covid19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04435041,"Active, not recruiting","June 1, 2020","November 30, 2021",COVID-19,"Other,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1
NCT04513496,Not yet recruiting,"September 1, 2020","July 1, 2022","Telemedicine,HIV-1-infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,4000
NCT04394455,Enrolling by invitation,"June 30, 2020","December 30, 2020","Anxiety,Depressive Symptoms,Post Traumatic Stress Symptoms,Perceived Stress","Randomized,Parallel Assignment,The interventional models are brief cognitive behavioral therapy and crisis intervention therapy through telepsychiatry. Each arm will be divided into therapy groups with a maximum of 10 participants per group. Each therapy session will be directed by a therapist and a co-therapist using a predefined structure for each intervention, with a duration of 60-90 minutes per session.,Treatment,Single (Investigator),Investigators will not take part in the baseline symptom evaluation of subjects or the post-intervention evaluation.","gender:All,Min Age:18 Years,Max Age:N/A",No,236
NCT04497818,Completed,"June 16, 2020","July 25, 2020","Covid19,Fear,Dental Anxiety","Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:20 Years,Max Age:N/A",No,385
NCT04481477,Not yet recruiting,September 2020,"December 31, 2020",Covid19,"Case-Only,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,450
NCT04429828,Not yet recruiting,"June 13, 2020","December 30, 2020",Psychological Wellbeing,"N/A,Single Group Assignment,All students have access to the COVID-19 educational package to support psychological wellbeing in healthcare students (usual practice). In this study the investigators will conduct semi-structured qualitative interviews with healthcare students about their mental wellbeing, and use of this e-package.,Supportive Care,None (Open Label),This is an evaluation of an educational learning package, which is a form of 'supportive intervention' for students provided during the coronavirus pandemic. Therefore the investigators will conduct interviews with people who have used the e-package. The investigators will interview up to 45 participants.","gender:All,Min Age:N/A,Max Age:N/A",No,45
NCT04443270,Not yet recruiting,"July 27, 2020","January 31, 2021",COVID-19,"Non-Randomized,Parallel Assignment,Controlled Clinical Trial,Prevention,Single (Outcomes Assessor),The Outcome Assessor will be an external member of the Internal Medicine Service, which will be blinded to the intervention.","gender:All,Min Age:18 Years,Max Age:59 Years",No,200
NCT04501978,Recruiting,"August 4, 2020",July 2021,Covid19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,10000
NCT04542395,Not yet recruiting,"December 1, 2020","November 30, 2022",Coronavirus,"N/A,Single Group Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,310
NCT04416438,Recruiting,"May 18, 2020","December 31, 2020","Myeloproliferative Neoplasm,COVID-19 Infection","Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04414631,Recruiting,"August 6, 2020",July 2021,Coronavirus Infections,"Randomized,Parallel Assignment,Randomized, open-label, parallel-group, controlled, multi-center clinical trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:85 Years",No,120
NCT04472611,Not yet recruiting,"August 1, 2020","August 1, 2022",SARS-CoV-2,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,466
NCT04390126,"Active, not recruiting","April 20, 2020","November 7, 2021","Chronic Coronary Syndrome,Heart Failure,AMD and Macular Edema,Chronic Respiratory Failure,Hemophilia,Malignant Hemopathy,Multiple Sclerosis,Horton's Disease","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:4 Years,Max Age:N/A",No,1200
NCT04433286,Not yet recruiting,"June 15, 2020","August 31, 2020","Physical Stress,Career Burnout,Satisfaction","Other,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1000
NCT04544878,Recruiting,"March 26, 2020","June 1, 2021","Covid19,Pediatric ALL,Infection,Critical Illness,SARS-CoV Infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04547660,Recruiting,"July 16, 2020",October 2021,Covid19,"Randomized,Parallel Assignment,Randomized, open-label, phase 3, comparing best supportive care (BSC, no investigational drugs allowed) and convalescent plasma, along BSC.,Treatment,Single (Outcomes Assessor),Outcomes will be analyzed by blinded investigators. Group allocation will not be disclosed during statistical analysis.","gender:All,Min Age:18 Years,Max Age:N/A",No,160
NCT04475991,Not yet recruiting,August 2020,January 2021,COVID-19,"Randomized,Parallel Assignment,100 participants will be included and allocated in 4 groups of 25 each [Currently used therapy (CT), Maraviroc+CT, Favipiravir+CT and Maraviroc+Favipiravir+CT]. Group assignment will be determined by a random 100 number table.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,100
NCT04524598,Recruiting,"July 20, 2020","December 31, 2020",Depression,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:13 Years,Max Age:21 Years",No,410
NCT04435379,Recruiting,"June 18, 2020","May 31, 2021","Infection, Respiratory Tract","Randomized,Parallel Assignment,Subjects who fulfil the inclusion/exclusion criteria will be centrally randomized in a 1:1 ratio to receive a single dose (0.1 ml) of either VPM1002 or Placebo.,Prevention,Triple (Participant, Investigator, Outcomes Assessor),The reconstitution of trial intervention will be done by unblinded site personnel who will not be involved in the collection or evaluation of outcome data. Administration of the trial intervention will be done by blinded site personnel.","gender:All,Min Age:60 Years,Max Age:N/A",No,2038
NCT04412317,Recruiting,"June 3, 2020","May 31, 2021",Covid-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:14 Years",No,600
NCT04358042,Recruiting,"April 24, 2020","January 1, 2023","Psychiatric Disorder,Covid19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:15 Years,Max Age:N/A",No,250
NCT04357340,Completed,"April 2, 2020","May 30, 2020","Covid-19,Pneumonia,SARS Pneumonia","Randomized,Parallel Assignment,All the enrolled participants will be allocated to the intervention of control groups using blocked-balanced randomization method.,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:75 Years",No,40
NCT04352699,Completed,"March 15, 2020","May 1, 2020","Surgery,Complication of Surgical Procedure,COVID","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04324606,"Active, not recruiting","April 23, 2020",October 2021,Coronavirus,"Randomized,Sequential Assignment,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:55 Years",No,1090
NCT04476589,Recruiting,"July 1, 2020","March 30, 2023","Covid19,Coma,Consciousness Disorder","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04486521,Recruiting,"July 22, 2020","July 22, 2021","Critical Illness,Corona Virus Infection,Cytokine Release Syndrome","Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:14 Years,Max Age:N/A",No,11000
NCT04359407,Recruiting,"April 27, 2020","January 31, 2021","Severe Acute Respiratory Syndrome Coronavirus 2,Electric Impedance,Prone Positioning","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,16
NCT04347382,Completed,"April 30, 2020","August 30, 2020","Coronavirus Infection,Sars-CoV2","Randomized,Parallel Assignment,Treatment,Triple (Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,313
NCT04534621,Not yet recruiting,"August 26, 2020","September 18, 2020",Covid19,"Other,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,948
NCT04356586,Completed,"May 4, 2020","August 21, 2020","COVID-19,Serology","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:70 Years",No,287
NCT04392778,Recruiting,"April 1, 2020",September 2020,"Covid19,Pneumonia,Multiple Organ Failure,Corona Virus Infection","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:40 Years,Max Age:60 Years",No,30
NCT04431180,Enrolling by invitation,"June 13, 2020","June 30, 2020",Blood Donation,"Randomized,Parallel Assignment,Health Services Research,None (Open Label)","gender:All,Min Age:18 Years,Max Age:60 Years",No,403535
NCT04482634,Not yet recruiting,August 2020,August 2022,"Pulmonary Rehabilitation,COVID-19","Randomized,Parallel Assignment,There will be two groups. The first group will perform the exercises at their home under remote supervision (tele-rehabilitation group) and the second group will perform the exercises at their home on their own (home exercise group),Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,122
NCT04427254,Not yet recruiting,January 2021,January 2023,COVID19,"N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04408222,"Active, not recruiting","April 16, 2020",May 2021,"Oxygen Deficiency,Coronavirus Infection","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,29
NCT04540419,Recruiting,"September 11, 2020","July 31, 2021",Covid19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:85 Years",No,500
NCT04426071,Not yet recruiting,June 2020,December 2020,"Brain Injuries,Stroke,Spinal Cord Injuries","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,142
NCT04392713,Recruiting,"April 15, 2020",July 2020,COVID,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:15 Years,Max Age:65 Years",No,100
NCT04403906,Not yet recruiting,June 2020,August 2021,"COVID,SARS-CoV 2","N/A,Single Group Assignment,Evaluation of diagnostic test - point of care,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04429334,Not yet recruiting,August 2020,March 2021,COVID19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:75 Years",No,60
NCT04412226,Not yet recruiting,"June 10, 2020","June 30, 2020","Intubation, Intratracheal,COVID-19","Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,13
NCT04345692,Recruiting,"March 26, 2020","December 31, 2021",COVID-19,"Randomized,Parallel Assignment,Randomized, 2 arm, open label hydroxychloroquine plus usual care compared to usual care in hospitalized patients,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:95 Years",No,350
NCT04452474,Not yet recruiting,"June 30, 2020","January 29, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:100 Years",No,376
NCT04420676,Not yet recruiting,August 2020,December 2022,COVID,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,108
NCT04411602,Recruiting,"April 7, 2020","December 31, 2020","Severe Acute Respiratory Syndrome,COVID","N/A,Single Group Assignment,Severely ill patients with COVID-19 severe respiratory distress,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,90
NCT04405076,"Active, not recruiting","May 29, 2020",August 2021,SARS-CoV-2,"Randomized,Sequential Assignment,Prevention,Double (Participant, Investigator),Observer-blind","gender:All,Min Age:18 Years,Max Age:N/A",No,600
NCT03871491,Recruiting,"September 1, 2020","September 1, 2023","Maternal Death,Maternal Infections Affecting Fetus or Newborn,Neonatal SEPSIS,Maternal Sepsis During Labor,Neonatal Death,Postpartum Sepsis","Randomized,Parallel Assignment,Randomized, placebo-controlled, parallel multicenter clinical trial. Women in labor will be randomized with one-to-one ratio to intervention/placebo.,Prevention,Triple (Participant, Care Provider, Investigator),Both the azithromycin and placebo will be procured from the same manufacturer. The packaging will be standardized across sites and will be labeled as: ""Azithromycin 2 g or Placebo"", with the expiration data and a unique identifier.
Clinical and research staff as well as the women will be masked to treatment status unless there is a serious adverse event potentially related to the treatment modality that requires unmasking for safety reasons. There will be one pharmacist at each site who will monitor randomization, drug supply, and safety. If concerns about randomization or participant safety are identified, the data coordinating center will authorize and instruct the study pharmacist to apply un-masking procedures.","gender:Female,Min Age:18 Years,Max Age:45 Years",No,34000
NCT04484025,Not yet recruiting,August 2020,December 2020,"Covid19,Corona Virus Infection,Coronavirus,Coronavirus Infection","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04537572,Not yet recruiting,September 2020,September 2022,COVID-19,"N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:99 Years",No,300
NCT04382131,Recruiting,"June 23, 2020","October 31, 2020","Upper Respiratory Tract Infections,Virus,COVID,Virus Shedding,Virus Diseases","Randomized,Parallel Assignment,ELVIS COVID-19 is a pragmatic web-based Bayesian adaptive randomised controlled, parallel group trial of hypertonic saline nasal irrigation and gargling (HSNIG) compared to standard care in participants with clinically suspected or confirmed COVID-19 being managed at home. Participants from Scotland will be self-recruiting via web based system which will randomise in a 1:1 ratio to perform HSNIG or not.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,405
NCT04357938,"Active, not recruiting","April 15, 2020","April 30, 2021",Severe Acute Respiratory Syndrome Coronavirus 2,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,145
NCT04273646,Not yet recruiting,"April 20, 2020","February 15, 2022","2019 Novel Coronavirus Pneumonia,COVID-19","Randomized,Parallel Assignment,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:65 Years",No,48
NCT04531345,Not yet recruiting,"September 1, 2020","October 15, 2020",Covid19,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,50
NCT04334044,Recruiting,"April 15, 2020","June 1, 2020","COVID-19,Severe Acute Respiratory Syndrome Coronavirus 2","N/A,Single Group Assignment,Use of ruxolitinib on patients with respiratory distress and pneumonia changes on chest computed tomography,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04370275,Recruiting,"April 23, 2020","May 31, 2020","COVID-19,Pneumonia, Viral","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,235
NCT04358211,Available,N/A,N/A,N/A,N/A,"gender:All,Min Age:18 Years,Max Age:N/A",N/A,N/A
NCT04285190,Withdrawn,"February 26, 2020","April 20, 2020","Coronavirus Disease 2019,Novel Coronavirus Pneumonia","Randomized,Parallel Assignment,An open-label, randomized, blank-controlled treatment clinical study,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:85 Years",No,0
NCT04528641,Recruiting,"August 10, 2020","July 31, 2021",COVID-19,"Non-Randomized,Sequential Assignment,Phase I, open-label, dose escalation, clinical trial to assess the safety and immunogenicity of the candidate GRAd-COV2 vaccine in 90 healthy volunteers aged 18-55 years and elderly volunteers aged 65-85 years. The vaccine will be administered intramuscularly once in time.,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:85 Years",No,90
NCT04480606,Not yet recruiting,"August 1, 2020","November 20, 2020",Exercise Program,"Randomized,Parallel Assignment,Prevention,Single (Outcomes Assessor)","gender:All,Min Age:65 Years,Max Age:80 Years",No,88
NCT04546776,Enrolling by invitation,"September 8, 2020",June 2022,SARS-CoV Infection,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04555109,Recruiting,"June 30, 2020","March 31, 2022",Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:17 Years,Max Age:65 Years",No,1000
NCT04393428,Completed,"March 1, 2020","June 30, 2020","COVID-19,Renal Replacement Therapy,Acute Kidney Injury","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,100
NCT04349592,Recruiting,"April 14, 2020","August 30, 2020",Covid19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double-blinded trial","gender:All,Min Age:18 Years,Max Age:N/A",No,456
NCT04355247,Recruiting,"April 14, 2020","April 30, 2021",Covid-19,"N/A,Single Group Assignment,This is a pilot Phase II exploratory study. It is a non-randomized study which will be carried out at Auxilio Mutuo Hospital and possibly at other institutions to be recruited.
The investigator plans to enter a total of 20 patients in order to determine whether the risk of progressing to respiratory failure can be reduced by administering corticosteroids.
The investigator assume that virtually all patients who met the criteria for entry into this trial will develop respiratory insufficiency if left untreated.
If </= 50% of patients with high risk develop respiratory failure the investigator will consider the treatment as successful.,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04359095,Recruiting,"August 18, 2020","February 28, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,1200
NCT04496245,Recruiting,"August 24, 2020","June 30, 2021","Respiratory Viral Infection,Covid19","Randomized,Parallel Assignment,Participants will be randomized to either Group 1 (waitlist control, delayed treatment group) or Group 2 (initial treatment) for treatment for a period of 3 months with 3 months follow-up off treatment,Prevention,None (Open Label),Participants will be randomised to the wait list group (Group 1) or the initial intervention group (Group 2) using a one-to-one ratio, stratified by hospital and department [High risk, lower risk].","gender:All,Min Age:18 Years,Max Age:100 Years",No,1000
NCT04357808,Recruiting,"April 13, 2020",December 2020,Covid-19,"Randomized,Parallel Assignment,Randomised, open-label, single-center, comparative trial of sarilumab plus standard of care vs. standard of care in a 2:1 ratio.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04383899,Recruiting,"September 30, 2020","November 30, 2020",Coronavirus Infection,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,200
NCT04321616,Recruiting,"March 28, 2020",November 2020,"SARS-CoV Infection,COVID 19,Acute Respiratory Distress Syndrome ARDS","Randomized,Parallel Assignment,An open randomized adaptive controlled trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,700
NCT04473547,Recruiting,"July 15, 2020",December 2020,Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,215
NCT04348240,Recruiting,"April 16, 2020","July 1, 2021",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04569825,Recruiting,"August 1, 2020","October 15, 2020",Clinical Trial,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,250
NCT04344197,Enrolling by invitation,"April 2, 2020","April 15, 2020","Surgery,COVID,Asymptomatic Patient,Covid-19,Preventive Measures","Other,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1200
NCT04382040,Recruiting,"May 8, 2020",January 2021,"COVID-19,Corona Virus Infection,SARS-CoV 2,Coronavirus,Coronavirus Infection","Randomized,Parallel Assignment,Patients will be randomized in a manner of 2:1 for study drug (ArteminC) and Standard of Care to Placebo and Standard of Care.
Patient study period will last 2 weeks. During this time, patients will be monitored for adverse events.
There will be a follow up period (until hospital discharge) in order to check side effects and study drug efficacy,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04334382,Recruiting,"April 2, 2020","December 31, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:45 Years,Max Age:N/A",No,1550
NCT04317040,"Active, not recruiting","April 8, 2020",December 2020,Covid19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,241
NCT04413071,Completed,"May 25, 2020","June 12, 2020","SARS-CoV 2,COVID-19,Coronavirus,Cardiac Magnetic Resonance,Myocarditis,Cardiac Anomaly","Cohort,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:71 Years",No,142
NCT04519411,Recruiting,"May 21, 2020","January 31, 2021",COVID 19,"N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:N/A,Max Age:17 Years",No,10
NCT04356482,Recruiting,"May 20, 2020",December 2020,"COVID-19,SARS-CoV 2,Convalescence,Plasma,Doses","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:16 Years,Max Age:N/A",No,90
NCT04517422,Recruiting,"August 19, 2020","January 31, 2021",SARS-CoV Infection,"Randomized,Parallel Assignment,Randomized controlled trials. 300 subjects (18-60 years old) will be allocated to receive a combination of Lactobacillus plantarumCECT7481, Lactobacillus plantarum CECT 7484, Lactobacillus plantarum CECT 7485, and P. acidilactici CECT 7483 (branch one) or placebo (branch two),Other,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),All study staff, including the Principal Investigator and the persons performing the subject assessments, will be blinded during the study. Sealed individual treatment code envelopes will be kept at the clinic to be able to break the code if any emergency occurs, as judged by the Investigator","gender:All,Min Age:18 Years,Max Age:60 Years",No,300
NCT04398303,Not yet recruiting,May 2020,October 2020,COVID-19 Pneumonia,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:85 Years",No,70
NCT04552392,Not yet recruiting,"September 20, 2020","October 20, 2020",Quarantine,"Case-Only,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:60 Years",No,100
NCT04532554,Withdrawn,"October 26, 2020","December 20, 2020",Covid19,"Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04351243,Recruiting,"April 12, 2020",March 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,270
NCT04335552,Terminated,"April 17, 2020","June 26, 2020",SARS-CoV-2,"Randomized,Factorial Assignment,Patients will be initially randomized to one of two arms in a 1:1 ratio: 1) Standard of care treatment or 2) Standard of care treatment plus 5 days of hydroxychloroquine. Participants who meet eligibility criteria to receive azithromycin will undergo a second randomization in a 1:1 ratio to receive additional concurrent therapy.,Treatment,None (Open Label)","gender:All,Min Age:12 Years,Max Age:N/A",No,11
NCT04371393,Recruiting,"April 30, 2020",April 2022,"Mesenchymal Stromal Cells,Remestemcel-L,Acute Respiratory Distress Syndrome,COVID","Randomized,Parallel Assignment,This will be a randomized (1:1 ratio), double blind, parallel design, placebo controlled trial.,Treatment,Triple (Participant, Investigator, Outcomes Assessor),This is a randomized clinical trial, in which the patients and investigators are masked to treatment assignment.","gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04324463,Recruiting,"April 21, 2020","June 30, 2021","Coronavirus,Severe Acute Respiratory Syndrome","Randomized,Parallel Assignment,Open-label, parallel group, factorial, randomized controlled trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,4000
NCT04542330,Not yet recruiting,"September 11, 2020",March 2022,"Covid19,Non-specific Effects of Vaccines,Heterologous Immunity,Morbidity,Immunosenescence,Vaccine Preventable Disease","Randomized,Parallel Assignment,Placebo-controlled randomized trial.,Prevention,Double (Participant, Outcomes Assessor),Participants will be blinded to treatment. The physicians administering the BCG vaccine or placebo will not be blinded.","gender:All,Min Age:65 Years,Max Age:110 Years",No,1900
NCT04523831,Completed,"June 1, 2020","September 10, 2020",Covid19,"Randomized,Parallel Assignment,Patient will be randomized 1:1 to placaebo with standard care and combined doxycycline and ivermectin with standard care.,Treatment,Double (Participant, Investigator),Double blind (The participant and the clinicians/data collectors will be unaware of the treatment the participant receives).The drugs will be labelled with a random code number","gender:All,Min Age:18 Years,Max Age:N/A",No,400
NCT04577235,Completed,"June 5, 2020","September 5, 2020",COVID-19,"Randomized,Parallel Assignment,Diagnostic,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,29
NCT04409886,Not yet recruiting,"June 1, 2020","March 30, 2021","COVID, Coronavirus","Randomized,Parallel Assignment,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04329897,Completed,"April 5, 2020","June 1, 2020","Hip Osteoarthritis,Knee Osteoarthritis,Mental Stress,Coronavirus","Randomized,Parallel Assignment,Parallel Assignment Two study groups. The intervention group and the control group that does not receive the intervention,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,90
NCT04508985,Not yet recruiting,"September 1, 2020","September 1, 2021","COVID-19,Cardiovascular Diseases","Randomized,Sequential Assignment,Open-label, randomized, study of approximately 40 adults. The following groups of participants will be considered: i) within 48 hours of diagnosis of COVID-19; ii) who have received a diagnosis of COVID-19 from another facility and are within 48 hours of transfer to a study recruitment site (Royal Victoria Hospital, Montreal General Hospital, and Jewish General Hospital [all in Montreal, Quebec, Canada])). Participants will be randomized 1:1 to an upfront temporary discontinuation) of RAAS inhibition for the duration of the hospitalization (and to consider re-initiate on discharge) versus a strategy continuation of RAAS inhibition.,Treatment,None (Open Label),The patient and the treating doctor will be informed of the assigned treatment.","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04429594,Not yet recruiting,"July 15, 2020","December 31, 2025",Coronavirus Infections,"N/A,Single Group Assignment,Basic Science,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04381364,Recruiting,"May 29, 2020","December 31, 2020","Covid-19,Pneumonia, Viral,Sars-CoV2","Randomized,Parallel Assignment,This multicenter study is an open-labelled, randomized clinical trial for 1:1 ratio of ciclesonide or control arm,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,446
NCT04567979,"Active, not recruiting","June 11, 2020","October 30, 2020","Covid19,Cancer,Tumor","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,149
NCT04371926,Withdrawn,June 2020,July 2021,COVID-19,"Randomized,Parallel Assignment,Symptomatic patients will be randomized to hydroxychloroquine (HCQ) vs no-HCQ group.
Similarly, hospital staff with high risk of exposure will be randomized to HCQ vs no-HCQ group,Prevention,Single (Investigator)","gender:All,Min Age:18 Months,Max Age:85 Years",No,0
NCT04348214,Recruiting,"April 22, 2020","December 1, 2020",Coronavirus Disease (COVID-19),"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,3000
NCT04333368,Recruiting,"April 6, 2020","April 6, 2022","Severe Acute Respiratory Syndrome Coronavirus 2,Severe Acute Respiratory Distress Syndrome","Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04356560,Enrolling by invitation,"March 23, 2020","December 31, 2020",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,300
NCT04475120,Completed,"April 15, 2020","July 2, 2020",Covid19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:20 Years,Max Age:N/A",No,60
NCT04395599,Not yet recruiting,May 2020,October 2020,"Sars-CoV2,Surgery,COVID","N/A,Single Group Assignment,COVID19 patients undergoing visceral surgery,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04315870,Recruiting,"January 1, 2020","April 30, 2020",Infection Viral,"Cohort,Other","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:50 Years",No,20
NCT04485429,Recruiting,"July 20, 2020","December 31, 2020",COVID-19,"Randomized,Factorial Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,268
NCT04322279,Recruiting,"March 9, 2020","June 1, 2021",Coronavirus,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,300
NCT04368156,Recruiting,"April 20, 2020","July 31, 2020",Covid-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,90
NCT04445324,"Active, not recruiting","August 25, 2020",December 2020,"Psychotic Disorders,Anxiety Depression","Randomized,Parallel Assignment,Supportive Care,Double (Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04488562,Recruiting,"May 8, 2020","December 31, 2021","COVID-19,Pulmonary Fibrosis","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04377412,Recruiting,"May 1, 2020","October 31, 2020","Anxiety,Depression,Pregnancy Related","Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:N/A",No,8500
NCT04343755,Recruiting,"April 9, 2020",April 2021,COVID-19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,55
NCT04494893,Recruiting,"April 24, 2020","January 31, 2021",Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:89 Years",No,1000
NCT04460183,Recruiting,"July 29, 2020","April 23, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04390152,Not yet recruiting,September 2020,July 2021,Acute Respiratory Distress Syndrome,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Patient code will be stored in sealed, opaque envelops with their respective codification. These envelops will be stored in Clinica Somer's Research Unit and the only person with access permission will be the pharmaceutical chemist in charge. Treatment delivery (MSC or placebo) will also be in charge of the chemist, guaranteeing blinding of patient and healthcare professionals. Data analysis will be done by people blind to the treatment received by each patient.","gender:All,Min Age:18 Years,Max Age:80 Years",No,40
NCT04485364,"Active, not recruiting","April 14, 2020","October 31, 2020","Coronavirus,Covid19","Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04284046,Completed,"January 31, 2020","February 18, 2020",CT Scores Predict Mortality in 2019-nCoV Pneumonia,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,39
NCT04382534,Recruiting,"March 10, 2020","December 31, 2020","Covid19,Respiratory Rehabilitation,Cross-sectional Study,Cohort Study","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,300
NCT04426292,Recruiting,"May 12, 2020","May 12, 2021",Sars-CoV2,"N/A,Single Group Assignment,Health Services Research,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,3500
NCT04492371,Recruiting,"July 1, 2020",July 2021,"Multiple Myeloma,Covid19,Corona Virus Infection","Cohort,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:99 Years",No,500
NCT04384926,Recruiting,"March 30, 2020","December 31, 2020","COVID-19,Coronavirus,Cancer,Surgery","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04497948,Not yet recruiting,"July 31, 2020","September 28, 2020",COVID-19,"Non-Randomized,Single Group Assignment,Single group multi dose study. Participants to receive Acalabrutinib + PPI and Best Supportive Care.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04495101,Recruiting,July 2020,November 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04432038,Recruiting,"June 19, 2020","June 30, 2021","Adult,Global Health","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50000
NCT04359251,Completed,"March 5, 2020","March 25, 2020","COVID-19,Mechanical Ventilation Pressure High,Acute Respiratory Distress Syndrome","Non-Randomized,Crossover Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,20
NCT04451317,Not yet recruiting,August 2020,August 2020,"Physical Activity,COVID-19","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,600
NCT04365153,"Active, not recruiting","April 24, 2020","December 31, 2020","COVID-19,SARS-CoV 2","Randomized,Factorial Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,45
NCT04504877,Recruiting,"June 16, 2020","September 30, 2020","Covid19,Burn Out,Post Traumatic Stress Disorder","Randomized,Parallel Assignment,Prevention,Single (Outcomes Assessor),Volunteers, administrative staff, laboratory technicians, doctors who will carry out the assessments by phone, and statisticians will be blind to the treatment group and will not know about the group treatment information.","gender:All,Min Age:24 Years,Max Age:60 Years",No,102
NCT04460547,Not yet recruiting,"July 25, 2020","September 20, 2020",COVID-19,"Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:1 Year,Max Age:N/A",No,200
NCT04291053,Not yet recruiting,"April 1, 2020","September 1, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,550
NCT04357574,Enrolling by invitation,"April 14, 2020",April 2021,"COVID-19,Cancer","Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04442191,Recruiting,"May 5, 2020","May 5, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Investigator, Outcomes Assessor),The patient's nurse will be instructed to place the blood product in a paper bag so the label on the product is not visible to the study physicians or to the patient.","gender:All,Min Age:40 Years,Max Age:N/A",N/A,50
NCT04508556,Not yet recruiting,September 2020,April 2021,Covid19,"Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04435795,Not yet recruiting,"June 25, 2020","March 25, 2021",COVID 19,"Randomized,Factorial Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,454
NCT04338698,Recruiting,"April 22, 2020","November 30, 2020",COVID 19,"Randomized,Parallel Assignment,Adaptive design (sample size given below is indicative),Treatment,Double (Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04344145,Completed,"April 16, 2020","May 29, 2020",COVID-19,"Case-Control,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,693
NCT04533347,Not yet recruiting,October 2020,February 2021,COVID 19 Disease,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,275
NCT04372472,"Active, not recruiting","April 7, 2020","May 29, 2020","Sepsis,COVID-19","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT03944447,Recruiting,"December 1, 2018","December 31, 2025","Chronic Pain,Chronic Pain Syndrome,Chronic Pain Due to Injury,Chronic Pain Due to Trauma,Fibromyalgia,Seizures,Hepatitis C,Cancer,Crohn Disease,HIV/AIDS,Multiple Sclerosis,Traumatic Brain Injury,Sickle Cell Disease,Post Traumatic Stress Disorder,Tourette Syndrome,Ulcerative Colitis,Glaucoma,Epilepsy,Inflammatory Bowel Diseases,Parkinson Disease,Amyotrophic Lateral Sclerosis,Chronic Traumatic Encephalopathy,Anxiety,Depression,Insomnia,Autism,Opioid-use Disorder,Bipolar Disorder,Covid19,SARS-CoV Infection,COVID-19,Corona Virus Infection,Coronavirus","Non-Randomized,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:7 Years,Max Age:N/A",No,200000
NCT04476719,"Active, not recruiting","July 9, 2020","August 20, 2020",Bioequivalence,"Randomized,Crossover Assignment,Other,None (Open Label)","gender:Male,Min Age:20 Years,Max Age:40 Years",No,18
NCT04375774,Recruiting,May 2020,May 2020,COVID,"Non-Randomized,Single Group Assignment,Enrolment will be a onetime selection of 10 healthy volunteers,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:60 Years",No,10
NCT04496141,"Active, not recruiting","July 27, 2020","November 30, 2020",Covid19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,70
NCT04371822,Not yet recruiting,August 2020,November 2020,COVID-19,"Non-Randomized,Sequential Assignment,Patients and method :
This study will performed on 56 participants tested positive for the presence of COVID-19 RNA by RT-PCR kit for RNA detection and 56 participants will divided into 8 equal groups,Treatment,None (Open Label),Patients
This study will performed on 56 participants tested positive for the presence of COVID-19 RNA by RT-PCR kit for RNA detection and 56 participants will divided into 8 equal groups","gender:All,Min Age:18 Years,Max Age:80 Years",No,56
NCT04343144,Not yet recruiting,"April 15, 2020","September 30, 2020",COVID19- Infection With SARS-CoV-2 Virus,"Randomized,Parallel Assignment,2 parallels arms randomized open-label multi center clinical trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,92
NCT04433013,Not yet recruiting,July 2020,February 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Outcomes Assessor)","gender:All,Min Age:21 Years,Max Age:N/A",No,300
NCT04558450,Not yet recruiting,September 2020,June 2032,"Covid19,Arterial Stiffness,Endothelial Dysfunction,Diastolic Dysfunction","Non-Randomized,Single Group Assignment,Prospective cohort study,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,360
NCT04363749,Not yet recruiting,"April 27, 2020","November 27, 2021","Covid19,Neurological Complication","Non-Randomized,Parallel Assignment,Basic Science,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04377646,Not yet recruiting,"May 4, 2020","July 31, 2020","Sars-CoV2,COVID19","Randomized,Parallel Assignment,Double blind randomized clinical trial with 3 arms,Prevention,Triple (Participant, Care Provider, Investigator),Random blind allocation.","gender:All,Min Age:18 Years,Max Age:65 Years",No,660
NCT04406181,Recruiting,"May 18, 2020","January 1, 2021","Anxiety and Fear,Anxiety Depression,Anxiety Postoperative,Psychological Stress","Non-Randomized,Parallel Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:90 Years",No,200
NCT04480593,Completed,"June 2, 2020","August 30, 2020",Covid19,"Randomized,Parallel Assignment,three parallel groups randomly assigned,Treatment,Single (Outcomes Assessor),The individual who evaluates the results of interest to the study will not have access to the study steps before the analysis.","gender:All,Min Age:18 Years,Max Age:N/A",No,120
NCT04351711,Recruiting,"April 9, 2020",October 2020,"SARS-CoV-2,Covid-19","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04537559,Enrolling by invitation,"March 1, 2020","October 31, 2020",COVID-19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:16 Years,Max Age:N/A",No,40000
NCT04438850,Recruiting,"July 31, 2020",October 2020,Covid19,"Randomized,Sequential Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Ivermectin and placebo treatment will be double blinded, i.e. the treatment will be unknown to both the subject and the treating physician. The hospital pharmacist will be unblinded to study treatment because in charge to prepare the study treatment according to randomization arm.","gender:All,Min Age:18 Years,Max Age:N/A",No,102
NCT04393649,Recruiting,"April 20, 2020","April 19, 2021","COVID,Social Isolation,Anxiety,Frailty","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:70 Years,Max Age:N/A",No,20000
NCT04382794,Completed,"May 14, 2020","June 15, 2020",Covid19,"Case-Control,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,338
NCT04376788,Recruiting,"May 20, 2020","September 1, 2020",COVID-19,"Randomized,Parallel Assignment,Group I:
Will receive exchange transfusion by venesection of 500cc blood with good replacement of one unit packed washed RBCs daily for 3 days according to daily clinical and investigational follow up
Group II Will receive IV methylene blue 1 mg/kg IV over 30 minutes with 200 CC plasma from convalescent matching single patient by plasma extractor machine for 3 days according to daily clinical and investigational follow up.
Group III Will receive exchange transfusion by venesection of 500cc blood with good replacement of one unit packed washed RBCs and IV methylene blue 1 mg/kg IV over 30 minutes with 200 CC plasma from convalescent matching single patient by plasma extractor machine for 3 days according to daily clinical and investigational follow up.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:65 Years",No,15
NCT04346329,Not yet recruiting,"April 20, 2020","October 1, 2020",COVID,"Randomized,Parallel Assignment,Phase III double-blind, randomized, placebo-controlled clinical study,Prevention,Double (Participant, Care Provider)","gender:All,Min Age:18 Years,Max Age:N/A",No,86
NCT04374149,"Active, not recruiting","April 30, 2020","December 1, 2020","Cytokine Release Syndrome,COVID19","Non-Randomized,Sequential Assignment,Treatment,None (Open Label)","gender:All,Min Age:12 Years,Max Age:80 Years",No,20
NCT04348474,Suspended,"April 20, 2020","July 31, 2020",Covid-19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04411563,Recruiting,"May 21, 2020",December 2020,Prognosis,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:65 Years",No,105
NCT04408196,Recruiting,"May 26, 2020","August 31, 2020",Rehabilitation,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04430049,Not yet recruiting,"June 22, 2020","January 22, 2022","Covid-19,Family Members,Critical Illness","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,240
NCT04391179,Recruiting,"May 31, 2020",December 2020,"COVID,Corona Virus Infection,Covid-19,SARS-CoV-2 Infection","Randomized,Parallel Assignment,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,80
NCT04355884,Not yet recruiting,"April 20, 2020","May 1, 2020",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04530656,Not yet recruiting,"August 28, 2020","August 28, 2021",COVID-19,"Randomized,Parallel Assignment,Prevention,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,168
NCT04357990,Recruiting,"September 4, 2020",March 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,128
NCT04340544,Recruiting,"April 22, 2020","September 30, 2022",COVID-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:99 Years",No,2700
NCT04310865,Suspended,November 2020,"June 30, 2021","COVID-19,Severe Pneumonia,Chinese Medicine","Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,116
NCT04477889,Recruiting,"June 20, 2020",December 2026,COVID-19,"Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04389476,Not yet recruiting,"June 15, 2020","July 31, 2023",The Psychological Impact of COVID-19,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:20 Years,Max Age:N/A",No,2500
NCT04512118,Completed,"March 15, 2020","July 30, 2020",Presence of COVID-19 Compatible CT Abnormalities,"Case-Only,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,22
NCT04390555,Recruiting,"April 30, 2020",July 2021,"COVID-19,Cardiovascular Diseases,Cardiovascular Risk Factor,Heart Failure","Cohort,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1500
NCT04334850,Recruiting,"April 20, 2020",August 2020,"Covid19,Pneumonia","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,194
NCT04468789,Not yet recruiting,November 2020,December 2022,HIV,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,150945
NCT04361591,Recruiting,"March 1, 2020",March 2021,"Liver Transplant; Complications,COVID19,Respiratory Failure","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,200
NCT04366791,Recruiting,"April 23, 2020","October 23, 2020","Pneumonia,Coronavirus Infection in 2019 (COVID-19),Severe Acute Respiratory Syndrome (SARS) Pneumonia","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,10
NCT04548908,Recruiting,"August 3, 2020","June 30, 2021",Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1300
NCT04452799,Not yet recruiting,"July 1, 2020","October 30, 2020",Coronavirus Infection,"Randomized,Parallel Assignment,Randomized double-blind controlled Parallel study,Treatment,Double (Participant, Care Provider),Randomized double-blind controlled Parallel study","gender:All,Min Age:18 Years,Max Age:65 Years",No,100
NCT04526821,Not yet recruiting,"September 1, 2020","November 1, 2021",SARS-CoV-2,"Randomized,Parallel Assignment,Prevention,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:59 Years",No,336
NCT04432922,Not yet recruiting,"November 1, 2020","November 15, 2020",COVID19,"Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,15
NCT04335136,Recruiting,"April 30, 2020",December 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:80 Years",No,200
NCT04322786,"Active, not recruiting","January 1, 1998","March 31, 2020","Covid-19, Coronavirus, Angiotensin Converting Enzyme Inhibitors, Influenza, Electronic Health Records, Epidemiology, Comorbidity, Incidence, United Kingdom","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1302508
NCT04344457,Recruiting,"April 16, 2020","September 30, 2020",COVID-19,"N/A,Single Group Assignment,Open label, single arm study,Treatment,None (Open Label),Open Label","gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04346264,Enrolling by invitation,"April 27, 2020","September 30, 2020","Virus Diseases,COVID-19","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:6 Years,Max Age:85 Years",No,5500
NCT04363788,Completed,"February 28, 2020","April 24, 2020","Cardiac Arrest,Needle Stick,Injuries,Glowe","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,300
NCT04523181,Not yet recruiting,"September 21, 2020","March 31, 2021",Covid-19,"Randomized,Parallel Assignment,A Phase 2 Randomized, Double blind, Placebo Controlled, Proof of Concept Study to Evaluate the Safety and Efficacy of Antroquinonol in Hospitalized Patients with Mild to Moderate Pneumonia due to COVID 19,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double blind, Placebo Controlled","gender:All,Min Age:18 Years,Max Age:80 Years",No,174
NCT04402879,Recruiting,"July 21, 2020","June 1, 2021","Severe Acute Respiratory Syndrome Coronavirus 2,COVID-19,Acute Respiratory Distress Syndrome,ARDS,Hypoxemic Respiratory Failure","Randomized,Parallel Assignment,This is a prospective, unblinded, randomized controlled trial at four (4) medical sites in Calgary, Alberta.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,596
NCT04344782,Not yet recruiting,"April 15, 2020","November 30, 2020",COVID19 Pneumonia,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,130
NCT04410484,"Active, not recruiting","May 22, 2020",August 2020,"Inflammatory Bowel Diseases,Coronavirus Infection","Case-Control,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:16 Years,Max Age:100 Years",No,1500
NCT04437823,Recruiting,"June 1, 2020","June 30, 2021",Corona Virus Infection,"Randomized,Parallel Assignment,Group 1 (15 subjects) Fifteen (15) subjects will be treated with three intravenous infusion (IV) of 5 x 10^5 (per Kg body weight) UCMSCs delivered via peripheral intravenous infusion on days 1, 3 and 5 besides the standard care (SOC).
Group 2 (5 subjects) Five (5) subjects will be treated under SOC. From two subjects in group 1 will not be treated 24hrs apart. Patients will be randomized in a 1:3 ratio (SOC: UCMSC).,Treatment,None (Open Label)","gender:All,Min Age:30 Years,Max Age:70 Years",No,20
NCT04339790,Recruiting,"October 12, 2020","April 1, 2022","Healthy Volunteer,Mood Disorder,Anxiety Disorder,Preexisting Medical Condition","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,10000
NCT04523051,Recruiting,"April 1, 2020","May 1, 2021",Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,40
NCT04391140,Recruiting,"May 13, 2020",June 2021,"COVID,ARDS,Acute Respiratory Distress Syndrome,Acute Respiratory Failure,Corona Virus Infection","Randomized,Parallel Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,248
NCT04393246,Recruiting,"July 3, 2020","June 15, 2021",COVID-19,"Randomized,Parallel Assignment,TACTIC-E is a randomised, parallel arm, open-label platform trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,1407
NCT04338126,Not yet recruiting,"September 30, 2020","December 31, 2020",COVID19,"Randomized,Parallel Assignment,Randomized, placebo-controlled, double blind comparison,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Pharmacy prepares medications that are coded","gender:All,Min Age:19 Years,Max Age:N/A",No,60
NCT04377776,Completed,"May 4, 2020","May 18, 2020","Kidney Transplant,Pancreas Tranplant,Pancreatic Islet Transplantation","Cohort,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:90 Years",No,644
NCT04514627,Recruiting,"July 13, 2020","July 31, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04344535,Enrolling by invitation,"April 8, 2020","August 31, 2021",COVID,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Staff in Transfusion Services (Blood Bank) at Stony Brook will be unblinded so they can collect, store, and dispense either convalescent plasma or standard plasma. They will affix an approved label with all required information, e.g. bar code, blood type, expiration date, and will indicate that the bag contains convalescent plasma/standard plasma.","gender:All,Min Age:18 Years,Max Age:N/A",N/A,500
NCT04567836,Recruiting,"June 1, 2020","December 1, 2020",Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,3000
NCT04475068,Recruiting,"July 17, 2020",October 2020,"Sars-CoV2,ARDS","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,12
NCT04545541,Not yet recruiting,October 2020,June 2022,"Covid19,Respiratory Failure","Randomized,Parallel Assignment,Treatment,Double (Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,202
NCT04557358,Recruiting,"July 1, 2020","December 31, 2020","Rheumatoid Arthritis,Quality of Life","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,346
NCT04547140,Not yet recruiting,September 2020,September 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04382391,Recruiting,"May 8, 2020","December 30, 2020","COVID,Corona Virus Infection,Respiratory Failure,Respiratory Distress Syndrome, Adult,ARDS, Human,SARS (Severe Acute Respiratory Syndrome)","Randomized,Parallel Assignment,Prospective, Randomized, Controlled,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04382924,Recruiting,"August 5, 2020",February 2022,COVID,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,682
NCT04411446,Recruiting,"August 12, 2020","December 28, 2020",COVID,"Randomized,Parallel Assignment,Two parallel arms randomized controlled trial. A sequential design will be used with the first primary outcome being the primary outcome for the first step. This step will include 200 patients. After reach this point, a review of the primary outcome (change in respiratory SOFA) will be done. According to these results, the Executive committee will decide to proceed the second step of the study and include the remaining 1065 patients to evaluate the second primary outcome (need for high dose of oxygen supplementation or mechanical ventilation).,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),The study will use a placebo identical to the active medication. The members of research team assessing the outcomes will not be aware of the treatment assignment.","gender:All,Min Age:18 Years,Max Age:N/A",No,1265
NCT04445285,Recruiting,"April 28, 2020","February 28, 2021",Covid19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,44
NCT04508868,Recruiting,"August 17, 2020",July 2021,"Depression,Depressive Symptoms","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:65 Years,Max Age:N/A",No,154
NCT04409483,Withdrawn,"June 1, 2020","December 31, 2021",Covid-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:12 Years,Max Age:N/A",No,0
NCT04339881,Not yet recruiting,"April 13, 2020","June 15, 2020",Sars-CoV2,"Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04408001,Recruiting,"June 4, 2020","June 4, 2021",Sars-CoV2,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,800
NCT04498065,"Active, not recruiting","March 1, 2020",July 2021,"Covid19,Non Ischemic Myocardial Injury,Myocardial Infarction,Myocarditis,Troponin Elevation","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04519385,Completed,"March 1, 2020","August 5, 2020","Pneumonia, Viral","Randomized,Parallel Assignment,dexamethsone group Tocilizumab group,Treatment,Double (Participant, Outcomes Assessor),single blind","gender:All,Min Age:18 Years,Max Age:N/A",No,69
NCT04354753,Completed,"March 28, 2020","April 17, 2020",COVID 19,"Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04335097,Recruiting,"April 22, 2020","December 20, 2025",COVID 19,"Randomized,Parallel Assignment,Two groups, control and intervention.,Supportive Care,None (Open Label),Sensor monitoring can not be masked since it is the prerequisite for the measures.","gender:All,Min Age:18 Years,Max Age:N/A",No,214
NCT04354805,Not yet recruiting,"August 1, 2020",November 2020,COVID-19,"Randomized,Parallel Assignment,Single centred, single-blinded randomised controlled trial. All subjects from a population of interest will be randomly assigned to one of two groups, one group who is exposed to the intervention or a second group who receive the routine care in the hospital.,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04574765,Recruiting,"April 16, 2020","April 16, 2021","Healthcare Worker,Covid19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100000
NCT04388631,Recruiting,"May 10, 2020","May 1, 2021",Coronavirus Disease 2019,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:Male,Min Age:18 Years,Max Age:60 Years",No,200
NCT04355897,Recruiting,"April 28, 2020",August 2020,COVID 19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,100
NCT04337047,Completed,"March 31, 2020","May 3, 2020","Stress, Psychological","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04518410,Recruiting,"August 19, 2020",February 2021,"Coronavirus,Covid19","Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator),Unblinded data will be provided to the Data and Safety Monitoring Board for interim analyses. Unblinded Day 28 data will also be provided to a small group of people from the company who owns the investigational agent, to assist the company in deciding if the agent should move into phase 3 evaluation; or in choosing a dose of their agent to move into phase 3 evaluation.","gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04389710,Recruiting,"April 15, 2020","April 14, 2021",COVID-19,"N/A,Single Group Assignment,Provide access to COVID-19 convalescent plasma for patients infected with SARS-CoV-2 currently hospitalized in acute care facilities,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04542213,Recruiting,"August 1, 2020","September 30, 2020","Hyperglycemia,Covid19","Randomized,Parallel Assignment,The study will include two parallel groups of intervention,Treatment,Triple (Care Provider, Investigator, Outcomes Assessor),Physicians who will be providing health support will not be aware of the treatment that patients will be receiving regarding this protocol, also the principal investigator and the personal who will be measuring glucose levels and prognosis, will not be aware of the group of treatment, since all the patients will be receiving the same protocol of insulin administration","gender:All,Min Age:18 Years,Max Age:75 Years",No,28
NCT04378595,Recruiting,"April 10, 2020","July 30, 2021",Food Insecurity,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,1000
NCT04431869,Recruiting,"August 18, 2020",July 2022,"Pregnancy Related,COVID,Intestinal Atresia,Limb Anomaly","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04351854,Not yet recruiting,"April 20, 2020","August 31, 2026","Corona Virus Infection,SARS-CoV 2","Case-Control,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,500
NCT04342156,Withdrawn,April 2020,October 2020,"Coronavirus Infection,Hydroxychloroquine Adverse Reaction","Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,0
NCT04391816,Recruiting,"October 12, 2020","December 31, 2024","Alcohol Drinking,Alcohol-Related Disorders,Pandemic,Psychological Stress","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,700
NCT04519398,Recruiting,"August 18, 2020","August 18, 2021","Covid19,Corona Virus Infection,Thrombosis,ARDS,Thrombophilia,Thromboses, Intracranial,Thromboses, Deep Vein,RAAS","Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT03042143,Recruiting,"January 7, 2019",October 2022,Acute Respiratory Distress Syndrome,"Randomized,Parallel Assignment,The phase 1 trial is an open label dose escalation pilot study in which cohorts of subjects with moderate to severe ARDS will receive increasing doses of a single infusion of Realist Orbcel-C in a 3+3 design. Initially 3 cohorts with 3 subjects/cohort.
In the completed Phase 1 REALIST trial, infusion of 400 million cells was achieved without any dose limiting toxicity at day 7 and has been approved by the DMEC as the intervention dose for this study.
The phase 2 trial is a randomized, double-blind, allocation concealed placebo-controlled study using the maximal tolerable dose as determined by the DMEC in patients with moderate to severe ARDS due to COVID-19.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),The cell therapy facility and clinical trials pharmacist will be unblinded. The unblinded individuals will keep the treatment information confidential and will not discuss or release information on treatment allocation to the patient, the investigator, or other unauthorized personnel.
As in prior studies of MSCs, the infusion bag containing either the cell product or placebo will be masked at the time of preparation in the clinical site's cell therapy facility so that the contents of the infusion bag are not visible to the investigators or to the clinicians who are administering the study drug. The contents of the infusion bag will be administered through a masked infusion set.","gender:All,Min Age:16 Years,Max Age:N/A",No,75
NCT04387253,Recruiting,"May 23, 2020","July 23, 2021","Identification of the Mother or Fetus Contamination by SARS Cov-2,Research the Presence of Viruses at Different Sites of the Mother and the Fetus or Father,The Survey Builds on a Network Work Already Organized Around the CPDPN of Poitou-Charentes,Analysis Laboratories of the Poitiers CHU","N/A,Single Group Assignment,Diagnostic,Single (Participant)","gender:All,Min Age:N/A,Max Age:N/A",No,80
NCT04446429,Recruiting,"July 2, 2020","January 31, 2021","COVID-19,SARS-CoV2,Androgenetic Alopecia,Prostate Cancer,Benign Prostatic Hyperplasia,SARS (Severe Acute Respiratory Syndrome)","Randomized,Parallel Assignment,This study is designed as a prospective, interventional, placebo controlled, double-blinded, randomized parallel assignment study.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:Male,Min Age:50 Years,Max Age:N/A",No,381
NCT04331106,Recruiting,"March 27, 2020",April 2021,Anxiety Related to the COVID-19 Pandemic,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,7500
NCT04345159,"Active, not recruiting","April 17, 2020","November 30, 2020","SARS-CoV-2,Systemic Lupus Erythematosus,Rheumatoid Arthritis,Sjogren's Syndrome,Psoriatic Arthritis","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,572
NCT04366050,Enrolling by invitation,"May 11, 2020",May 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,560
NCT04444401,Recruiting,"June 15, 2020","December 15, 2020","Neuroendocrine Tumors,COVID-19","Case-Only,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04453774,Not yet recruiting,"July 7, 2020",April 2023,Coronavirus,"N/A,Single Group Assignment,Health Services Research,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,1000
NCT04470622,Recruiting,"July 20, 2020",November 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04484207,Recruiting,"July 6, 2020","September 10, 2020","Brief Video-based Intervention,Vignette Based Intervention,Non Intervention Control Arm","Randomized,Parallel Assignment,Health Services Research,Single (Participant)","gender:All,Min Age:18 Years,Max Age:80 Years",No,200
NCT04345510,Not yet recruiting,"April 20, 2020","December 31, 2020",COVID-19 Infection,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04341792,Recruiting,"April 11, 2020",April 2021,"Infection Viral,Coronavirus,COVID-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04348942,Recruiting,"May 29, 2020","May 1, 2021",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,10000
NCT04567173,Recruiting,"September 21, 2020","June 30, 2021",Covid19,"Randomized,Parallel Assignment,This is a phase 3, randomized, non-placebo controlled, open-label, non-blinded, single-center clinical trial which will assess the efficacy and safety of anti-SARS-CoV-2 convalescent plasma given from the 3rd to 14th day of illness after the onset of symptoms in preventing ICU admission among COVID-19 patients compared to standard of care. Consequently enrolled patients will be randomized using the REDCap randomization module,Treatment,None (Open Label)","gender:All,Min Age:19 Years,Max Age:N/A",No,136
NCT04466670,Recruiting,"July 8, 2020","April 30, 2021",COVID-19,"Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,310
NCT04429724,Recruiting,"July 6, 2020",December 2020,COVID-19,"N/A,Single Group Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,6000
NCT04303299,Recruiting,"August 19, 2020","December 31, 2021","SARS-COV-2 Infections,COVID-19","Randomized,Parallel Assignment,Treatment,None (Open Label),The study is described as 'open' unblinded, however all clinical, virological and laboratory data, as well as adverse events were reviewed by two independent physicians, and all radiological images were reviewed by two independent radiologists who were blinded to the treatment assignments.
The study outcomes assessed blinded to randomized group ( PROBE design - prospective randomised open blinded evaluation)","gender:All,Min Age:16 Years,Max Age:100 Years",No,320
NCT04373889,Recruiting,"April 22, 2020","September 27, 2020","SARS-CoV-2,COVID-19","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,800
NCT04334460,Recruiting,"May 4, 2020",October 2020,Sars-CoV2,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,120
NCT04442178,Not yet recruiting,"June 30, 2020","December 31, 2020","COVID-19,Lymphocytopenia","Randomized,Parallel Assignment,randomized controlled of treatment vs placebo,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Unblinded Pharmacist will prepare blinded syringes of colorless drug or placeb","gender:All,Min Age:25 Years,Max Age:80 Years",No,48
NCT04339842,Completed,"April 10, 2020","May 31, 2020","Health Behavior,Eating Behavior","Case-Only,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,673
NCT04350931,Not yet recruiting,"April 20, 2020","December 1, 2020",Coronavirus Disease (COVID-19),"Randomized,Parallel Assignment,A block-randomization scheme will be generated by computer software. Participants will be randomized between 0.10 mL intradermal injection of BCG vaccine or placebo normal saline in a 2:1 ratio (600 will receive BCG & 300 will receive placebo saline). In Egypt, the available BCG vaccine is the Copenhagen (Danish strain).,Prevention,Single (Participant)","gender:All,Min Age:18 Years,Max Age:N/A",No,900
NCT04360551,Recruiting,"July 1, 2020","June 30, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator),Placebo controlled trial","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04406233,Recruiting,"May 23, 2020","May 23, 2022",SARS-CoV 2,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,176
NCT04403555,Recruiting,"June 1, 2020","December 3, 2030",COVID,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,200
NCT04437940,Recruiting,"June 15, 2020","July 30, 2020","COVID,Sars-CoV2","Cohort,Prospective","sampling_method:Probability Sample,gender:Female,Min Age:18 Years,Max Age:70 Years",No,35
NCT04532632,Recruiting,"September 1, 2020","September 20, 2020","Smell Disorder,Taste Disorders,Coronavirus Infection","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,40
NCT04555213,Not yet recruiting,September 2020,June 2021,Covid19,"Non-Randomized,Sequential Assignment,Part 1 Dose Escalation: 400mg, 600mg, 800mg, 1200mg & 1800mg Part 2 Dose Expansion : Recommended Phase 2 Dose,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04318366,Recruiting,"March 19, 2020","March 19, 2022",Coronavirus Infections,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04445623,Not yet recruiting,July 2020,January 2021,"COVID19,Thrombosis","Randomized,Parallel Assignment,Experimental phase 3 drug trial, randomized 1:1, double-blind, multicentre in patients treated with prasugrel vs placebo.,Treatment,Double (Participant, Care Provider),use of placebo tablets of the same shape, colour of the investigational drug. Identical time and route of administration.","gender:All,Min Age:18 Years,Max Age:99 Years",No,128
NCT04422509,Recruiting,"October 3, 2020","August 3, 2021",COVID-19,"Randomized,Parallel Assignment,controls will get standard of care and historical controls will be matched to the patients included,Treatment,None (Open Label)","gender:All,Min Age:16 Years,Max Age:N/A",No,80
NCT04348435,Enrolling by invitation,"May 14, 2020","April 30, 2021",COVID-19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04345289,Recruiting,"May 1, 2020","June 15, 2021","COVID,Corona Virus Infection,Viral Pneumonia","Randomized,Parallel Assignment,Adaptive multi-arm trial comparing convalescent plasma against control group. Interim analyses are included at 300 and 700 included participants to compare the effect and safety of the experimental treatment to control (placebo). The results of the interim analyses are used to decide if the treatments should be discontinued due to either futility or harm. The study is discontinued if either of the predefined stopping criteria are met.
Additional experimental treatments may be added as they become available. Any efficacious treatment identified in this or any other high-quality RCT may become the new SOC after consensus by national and international societies, and, thus, the control arm will change accordingly and in parallel.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Both convalescent plasma and placebo will be administered via a colored intravenous line with a colored sleeve disguising the fluid bag.
In order to achieve blinding of participants and treating personnel, patients randomized to active treatment will also receive placebo treatment.","gender:All,Min Age:18 Years,Max Age:N/A",No,1100
NCT04354818,Recruiting,"May 11, 2020","April 27, 2022","HIV-1-infection,Cancer,Primary Immune Deficiency Disorder,Immunosuppression Disorders,COVID-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04374370,Available,N/A,N/A,N/A,N/A,"gender:All,Min Age:6 Years,Max Age:99 Years",N/A,N/A
NCT04487951,Recruiting,"July 1, 2020","January 1, 2021",COVID19 Pneumonia,"Case-Control,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04547257,Not yet recruiting,"October 15, 2020","April 15, 2021",COVID-19,"Randomized,Parallel Assignment,The primary objectives are to demonstrate the safety and performance of the Exthera Medical Seraph 100 Microbind Affinity Blood Filter in the clinical improvement of COVID-19 patient, measured by the reduction of established and suspected prognostic parameters,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:90 Years",No,42
NCT04501458,Recruiting,"May 18, 2020","August 19, 2020",Covid19,"Non-Randomized,Crossover Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:100 Years",No,200000
NCT04365699,Recruiting,"April 8, 2020","December 31, 2020",COVID-19,"Non-Randomized,Single Group Assignment,All subjects hospitalized with COVID-19 infection hospitalized will be enrolled in the registry; a subgroup meeting specific entry criteria listed below will be enrolled in the open-label interventional trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04431453,Recruiting,"July 21, 2020",February 2021,COVID-19,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:N/A,Max Age:18 Years",Yes,52
NCT04407000,Completed,"June 23, 2020","August 8, 2020",Bioequivalence,"Randomized,Crossover Assignment,Other,None (Open Label)","gender:Male,Min Age:20 Years,Max Age:40 Years",No,30
NCT04444557,Completed,"April 17, 2020","May 1, 2020","Depression,Hemodialysis","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,97
NCT04363814,Recruiting,"June 10, 2020","July 31, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,100
NCT04366206,Recruiting,"March 14, 2020","July 31, 2020","COVID,SARS-CoV 2","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,143
NCT04418128,Not yet recruiting,"June 10, 2020","April 30, 2021","Corona Virus Infection,COVID-19","Randomized,Parallel Assignment,This study is an open-labelled, randomized clinical trial to evaluate the efficacy of nafamostate in patients with COVID-19 pneumonia.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:85 Years",No,84
NCT04511819,Recruiting,"August 28, 2020",November 2020,COVID-19,"Randomized,Parallel Assignment,This study is a randomized, double-blind, placebo-controlled study.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),This study will be performed in a double-blind fashion. The investigator, study staff, subjects, Sponsor, and monitor will remain blinded to the treatment until study closure.","gender:All,Min Age:50 Years,Max Age:N/A",No,410
NCT04462783,Not yet recruiting,October 2020,April 2021,"COVID,Covid-19,SARS-CoV 2","Non-Randomized,Parallel Assignment,Some patients will have pulse oximeters or be given one and provide data from these.,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04347239,Recruiting,"April 15, 2020","April 1, 2021",Coronavirus Disease 2019,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,390
NCT04437121,Completed,"April 30, 2020","May 24, 2020","Eating Behavior,COVID-19","Case-Crossover,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:24 Months,Max Age:18 Years",No,397
NCT04568564,Recruiting,"October 1, 2020","May 1, 2021","Lung Cancer,Physiotherapy","Randomized,Parallel Assignment,Randomized controlled trial,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04388826,Recruiting,"June 18, 2020","December 18, 2020","Respiratory Distress Syndrome, Adult","Randomized,Parallel Assignment,Randomized Placebo-Controlled,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double Blind Randomized Placebo-Controlled","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04466462,Completed,"May 26, 2020","June 30, 2020",SARS-CoV-2 Infection,"Case-Crossover,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04381286,Recruiting,"April 1, 2019","December 31, 2021","Mechanical Ventilation,SARS-CoV-2,COVID-19","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:90 Years",No,40
NCT04457505,Recruiting,"May 8, 2020","May 31, 2021","Acute Respiratory Distress Syndrome,Severe Pneumonia,Respiratory Failure","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,5000
NCT04412369,Not yet recruiting,June 2020,June 2021,"COVID19,Cardiovascular Diseases","Case-Only,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:99 Years",No,20
NCT04356690,Recruiting,"May 8, 2020",December 2021,COVID-19,"Randomized,Parallel Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,64
NCT04352400,Not yet recruiting,April 2020,December 2021,COVID19,"Randomized,Parallel Assignment,Randomized, double blind, placebo-controlled parallel-group trial, on top of best standard of care,Treatment,Double (Participant, Investigator),Randomization will be done with an algorithm tailored to the study design. Investigators and patients will be blinded to the treatment administered.","gender:All,Min Age:18 Years,Max Age:85 Years",No,256
NCT04420260,Not yet recruiting,July 2020,September 2020,COVID,"Randomized,Parallel Assignment,Combination of an oropharyngeal spray and an oral immunostimulant agent for the prevention of COVID-19 infection in healthcare providers in Medellín-Antioquia. Randomized clinical trial, parallel design, triple-blind, phase II.
Combination of an oropharyngeal spray and an oral immunostimulant agent for the prevention of COVID-19 infection in healthcare providers in Medellín-Antioquia. Randomized clinical trial, parallel design, triple-blind, phase II.
A four arm RCT is stipulated, in the following manner:
Group A: Active principle spray + Active principle capsules. Group B: Placebo spray + Active principle capsules. Group C: Active principle spray + Placebo capsules. Group D: Placebo spray + Placebo capsules.,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Once the participant has given its informed consent, and the research team has verified the fulfillment of the inclusion criteria, the prospect receives a text message, to be directed to the pharmaceutical service. The numbered scheme will be dispensed with the code of the intervention, following the order from the allocation listing, provided by the CTCC. The head of the pharmaceutical service will register the date and time of the first dose. He will provide indications for the use, handling and conservation of the products. Warning signs and symptoms and instructions for communication with the research team to address any concern the subject may have will be reviewed. He will remind the subject to avoid its damage or loss. He will give the participant instructions to return the container and surpluses of the products at the end of the trial (day 30), he will point out that they are for personal use only and that they cannot be shared.","gender:All,Min Age:18 Years,Max Age:60 Years",No,300
NCT04344171,Recruiting,"March 30, 2020","June 30, 2023",COVID-19,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,5000
NCT04476667,Recruiting,"June 15, 2020",May 2021,"Mental Health Issue,Covid19,Anxiety Disorders,Depression","Non-Randomized,Parallel Assignment,Participants selected for the e-psychotherapy group will receive a 9-week program that includes a combination of CBT, mindfulness, and problem-based therapy, in addition to TAU. The control group will receive treatment as usual during the first 9 weeks; if they still present significant symptoms (less than 50% response to treatment from baseline), they will be offered the e-psychotherapy program.,Treatment,None (Open Label)","gender:All,Min Age:14 Years,Max Age:65 Years",No,80
NCT04351191,Recruiting,"April 15, 2020","June 30, 2020","Sars-CoV2,Symptomatic Condition,Covid-19","Randomized,Parallel Assignment,Prospective double blind randomized superiority clinical trial.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:20 Years,Max Age:50 Years",No,400
NCT04373096,Not yet recruiting,"June 1, 2020","August 31, 2020",Covid19,"Randomized,Parallel Assignment,Prevention,Single (Outcomes Assessor),The research coordinator documenting all outcome data will be blinded to the group allocation.","gender:All,Min Age:20 Years,Max Age:75 Years",No,42
NCT04397614,Recruiting,July 2020,December 2021,"Sars-CoV2,Covid-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04262921,Recruiting,"February 8, 2020","August 7, 2023",Coronavirus Infections,"Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,5000
NCT04327479,Recruiting,"March 26, 2020","March 25, 2026","Cardiovascular Diseases,Cardiovascular Risk Factor,SARS","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,728
NCT04358809,Not yet recruiting,"April 30, 2020","April 30, 2021",COVID-19,"Randomized,Parallel Assignment,A randomized, double-blinded, two arms, placebo controlled, clinical trial,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,480
NCT04363346,Recruiting,"May 14, 2020",January 2022,COVID-19,"Non-Randomized,Sequential Assignment,The study starts with a fast-track design by proceeding in cohorts of one patient until the first DLT is observed. If no DLT is observed, escalation continues by one patient per cohort until Dose Strategy 3 is reached. If the MTD is not yet established by Dose Strategy 3, Dose Strategy 3 is expanded to 6 patients using the final stage of a ""3+3"" design. An extension of 4 additional patients is planned if FT516 continues to be safe for a total of 10 patients treated at the MTD.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:76 Years",No,12
NCT04373005,"Active, not recruiting","May 11, 2020","June 30, 2021","Covid-19,Cancer","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1000
NCT04478019,Recruiting,"July 7, 2020","April 30, 2021","COVID-19,SARS-CoV 2","Randomized,Crossover Assignment,Two-period cross-over trial with a wash-out period between two study intervention periods. Participants will be randomized in a 1:1 ratio to two intervention sequences: active intervention followed by a no intervention control; or no intervention control followed by active intervention,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,94
NCT04396600,Enrolling by invitation,"June 8, 2020","May 25, 2022","Stress,Stress Disorder,Stress, Psychological,Trauma, Psychological,Anxiety,Anxiety State,Post Traumatic Stress Disorder,Secondary Traumatic Stress,Professional Quality of Life,Stress Related Disorder,Stress Reaction,Stress Risk,Mental Resilience,Emotional Resilience","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1200
NCT04452630,Recruiting,"June 23, 2020","November 30, 2021",Cardiovascular Consequences After an Episode of COVID 19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04414059,Not yet recruiting,September 2020,August 2021,"SARS-CoV 2,Hospitalisation-Associated Infection","Case-Only,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,155
NCT04540029,Recruiting,"May 6, 2020","May 31, 2023",Prenatal Stress,"Case-Control,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:12 Months",No,600
NCT04329533,Recruiting,"April 13, 2020","July 30, 2020","Perceived Stress,Anxiety,Sleep Disturbance","Randomized,Parallel Assignment,Two arms including Arm 1 who receives a 30 day free trial of the app at the start of the study and Arm 2 who receives a 30 day free trial at the conclusion of the study. All participants will complete a baseline survey on perceived stress, anxiety, and sleep, a survey on stress at 2 weeks, and all three surveys again one month later.,Supportive Care,None (Open Label)","gender:Female,Min Age:18 Years,Max Age:99 Years",No,150
NCT04513470,Recruiting,"August 1, 2020",February 2021,COVID-19,"N/A,Single Group Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,5
NCT04353141,Recruiting,"April 28, 2020","December 31, 2020","COVID,Pregnancy Complications, Infectious,Pregnancy Related,Pregnancy, High Risk,Pregnancy Disease,Pneumonia,Pneumonia, Viral,Diagnoses Disease","Cohort,Prospective","sampling_method:Probability Sample,gender:Female,Min Age:N/A,Max Age:N/A",No,1850
NCT04393818,Completed,"May 5, 2020","August 24, 2020","Mental Health Disorder,Depression,Posttraumatic Stress Disorder,Burnout,Anxiety Disorders","Randomized,Parallel Assignment,Supportive Care,Triple (Participant, Care Provider, Outcomes Assessor),Participants will be blinded, as both the intervention and the control group will receive an App with information about management of mental health problems targeted at healthcare providers. The statisticians and outcome assessors (in this case the psychologists who will undertake the pre and post intervention psychological evaluations) will also be blinded. Only the PI and a research assistance will be unblinded.","gender:All,Min Age:18 Years,Max Age:N/A",No,560
NCT04365127,"Active, not recruiting","April 27, 2020","April 17, 2021","COVID-19,Sars-CoV2","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:Male,Min Age:18 Years,Max Age:N/A",No,40
NCT04344938,Not yet recruiting,April 2020,July 2020,Covid 19 Pandemic From Ethical View,"Ecologic or Community,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:60 Years",No,874
NCT04546841,Not yet recruiting,"September 30, 2020","December 20, 2021",COVID-19 Vaccine,"Sequential Assignment,Part I: Adults aged 18-55 years, n=12 Part II: Adults aged 56-74, n=12 Part III: Adults aged ≥ 75, n=12,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,36
NCT04313127,"Active, not recruiting","March 16, 2020","December 20, 2022",COVID-19,"Non-Randomized,Sequential Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:60 Years",No,108
NCT04377503,Not yet recruiting,May 2020,November 2020,"Cytokine Release Syndrome,Covid-19","Randomized,Crossover Assignment,Prospective randomized controlled phase 2 study,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04441476,"Active, not recruiting","April 21, 2020",November 2020,Psychological Strain,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,3000
NCT04363528,Recruiting,"April 24, 2020","October 30, 2020",Deep Vein Thrombosis,"N/A,Single Group Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04343651,"Active, not recruiting","April 1, 2020","August 31, 2020",Coronavirus Disease 2019,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:99 Years",No,86
NCT04275245,Recruiting,"February 3, 2020","December 31, 2020",2019-nCoVs Infection Pneumonia,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,20
NCT04463862,Recruiting,"June 4, 2020","September 4, 2020","COVID-19 Confirmed Cases,COVID-19 Mortality","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:50 Years,Max Age:N/A",No,250
NCT04354610,Recruiting,"April 27, 2020","October 18, 2020",COVID 19,"N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,57
NCT04449094,Completed,"February 28, 2020","April 4, 2020",COVID,"Ecologic or Community,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,200
NCT04424082,Recruiting,"June 7, 2020","September 7, 2020","Coronavirus,ARDS, Human","N/A,Single Group Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,40
NCT04537949,Recruiting,"September 9, 2020",December 2021,"Covid-19,Protection Against COVID-19","Non-Randomized,Sequential Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:85 Years",No,120
NCT04362930,Recruiting,"April 27, 2020","April 24, 2022","Neurologic Manifestations,Psychiatric Disorders,COVID-19","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04366089,Recruiting,"March 26, 2020","December 31, 2020","COVID,SARS-CoV 2,Pneumonia, Viral,Coronavirus Infection","Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,152
NCT04392141,Recruiting,"April 1, 2020","October 1, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:10 Years,Max Age:N/A",No,200
NCT04315987,Not yet recruiting,June 2020,August 2020,COVID-19 Pneumonia,"Randomized,Parallel Assignment,Patients will be randomized (1:1) to receive NestaCell (n=45) or Placebo (n=45).,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,90
NCT04412330,Recruiting,"May 1, 2020","May 1, 2021","Covid-19,Critical Illness,Post Intensive Care Unit Syndrome,Muscle Weakness","N/A,Single Group Assignment,Treatment,None (Open Label),Prospective study with one-treatment arm","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04492267,Recruiting,"July 7, 2020","January 7, 2021",Inflammatory Bowel Disease,"Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,700
NCT04510662,Recruiting,August 2020,April 2021,"COVID-19,Respiratory Insufficiency,Telmisartan,Respiratory Distress Syndrome, Adult","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04402229,Recruiting,"May 12, 2020","July 31, 2020","Nurse,Student,Post Traumatic Stress Disorder,COVID-19","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04408326,Recruiting,"June 1, 2020","May 1, 2021","COVID,Acute Respiratory Distress Syndrome","Case-Control,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04547283,Recruiting,"June 14, 2020","September 30, 2020","Covid19,Respiratory Failure","Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor),Clinicians were unblinded to treatment allocation and enrolled patients were considered unblinded. Clinical and safety outcomes were collected from the electronic health record by study investigators blinded to treatment assignment.","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04346199,Recruiting,"June 12, 2020","November 26, 2020",COVID-19,"Randomized,Parallel Assignment,Study will consist of two arms Arm 1 is acalabrutinib + best supportive care or Arm 2 is best supportive care alone,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:130 Years",No,140
NCT04399109,Recruiting,"May 20, 2020","May 19, 2021",COVID,"Non-Randomized,Parallel Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04320862,Recruiting,"April 3, 2020","December 31, 2021","COVID-19,SARS-CoV-2,Coronavirus,Influenza -Like Illness,Lower Resp Tract Infection,Upper Resp Tract Infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,200000
NCT04432779,Not yet recruiting,"June 25, 2020",June 2024,"Pregnancy,Covid-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,3000
NCT04387708,Not yet recruiting,"May 14, 2020","June 8, 2020",Anorexia Nervosa,"Family-Based,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,18
NCT04453579,Completed,"March 9, 2020","May 30, 2020","Obese,Morbid Obesity","Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:65 Years",No,116
NCT04515147,Not yet recruiting,"September 18, 2020","November 9, 2021","Coronavirus,Covid19,SARS-CoV-2,Severe Acute Respiratory Syndrome","Randomized,Sequential Assignment,Prevention,Triple (Participant, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,691
NCT04347278,Recruiting,"April 22, 2020","January 1, 2021",SARS-CoV-2,"Other,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:1 Year,Max Age:100 Years",No,1000
NCT04514874,Recruiting,"September 1, 2020",December 2020,"Covid19,SARS-CoV Infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04443673,Recruiting,"August 20, 2020","June 30, 2021","COVID-19,SARS-CoV Infection,SARS (Severe Acute Respiratory Syndrome),SARS Pneumonia,ARDS, Human,Pneumonia, Viral","Randomized,Parallel Assignment,Controlled, randomized, two branches, clinical trial.,Treatment,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,82
NCT04492254,Not yet recruiting,July 2020,July 2021,COVID-19,"Randomized,Parallel Assignment,Open label, multicentre, multi-national, randomized controlled trial.,Treatment,None (Open Label)","gender:All,Min Age:55 Years,Max Age:N/A",No,1370
NCT04482621,Recruiting,"September 14, 2020",July 2021,COVID-19,"Randomized,Parallel Assignment,This is a randomized double blind placebo controlled Phase 2 trial with a 12 patient lead-in to evaluate safety, prior to full enrollment to an additional 28 patients (for a total of 40 patients) to assess efficacy of decitabine in the treatment of critically ill patients with COVID-ARDS. The patients will be randomized in a 1:1 ratio to receive standard of care plus Decitabine or standard of care plus saline based placebo.,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04372576,Recruiting,"April 16, 2020",August 2020,"Ventilator Associated Pneumonia,Corona Virus Infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04485351,Recruiting,July 2020,September 2020,"Diabetes Mellitus,Coronavirus Infection,Metabolic Disease,Glucose Metabolism Disorders","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,700
NCT04490772,Not yet recruiting,July 2020,September 2020,Infectious,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,200
NCT04349241,Completed,"April 18, 2020","June 20, 2020",Coronavirus Disease (COVID-19),"Randomized,Parallel Assignment,A block-randomization scheme will be generated by computer software. 100 patients with confirmed COVID-19 will be randomized between favipiravir and the standard of care therapy (treated according to the national protocol) in a 1:1 ratio.
Group 1: 50 patients will receive the investigational drug favipiravir. Group 2: 50 patients will receive oseltamivir and hydroxychloroquine as the national standard of care therapy.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,100
NCT04464486,Enrolling by invitation,"April 21, 2020","May 31, 2021",Oncology,"Randomized,Parallel Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04336345,"Active, not recruiting","April 1, 2020","May 30, 2020","Coronavirus Infections,COVID-19,Viral Pneumonia Human Coronavirus","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04403009,Recruiting,"February 1, 2020","June 20, 2020","Coronavirus Disease 2019,Character of the Severe Patients","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:20 Years,Max Age:100 Years",No,100
NCT04501432,Recruiting,"July 14, 2020","December 31, 2020",Cardiac Rehabilitation,"Other,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04364802,Recruiting,"April 29, 2020",May 2021,"COVID-19,SARS-CoV 2","Non-Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:99 Years",No,250
NCT04347980,Recruiting,April 2020,August 2020,"Respiratory Distress Syndrome, Adult,COVID-19","Randomized,Parallel Assignment,Treatment,Single (Participant)","gender:All,Min Age:18 Years,Max Age:80 Years",No,122
NCT04497441,Recruiting,"June 10, 2020","August 15, 2020","Covid19,Information Seeking Behavior,Social Media,Perception, Self","Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:19 Years,Max Age:N/A",No,385
NCT04320511,Recruiting,"June 24, 2020",June 2022,"SARS-COV2,Severe Acute Respiratory Syndrome,COVID-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,25
NCT04421404,Recruiting,"June 9, 2020","April 30, 2021","COVID-19,Sars-CoV2","Randomized,Parallel Assignment,Subjects enrolled in the study will be randomized using a web based randomization procedure to receive convalescent plasma versus non-immune plasma at a 1:1 ratio.,Treatment,Triple (Participant, Care Provider, Investigator),Study investigators analyzing the data and participants will be blinded to the randomization. It may not be feasible to blind nursing staff to the treatment assignment to ensure proper ABO checking of the plasma unit at bedside per standard transfusion procedures, but every effort will be made to preserve blinding of the investigators, participant, and primary team providing care. An unblinded research assistant who is not involved in other aspects of the study will randomize the participant once enrolled. Randomization will be provided to an unblinded provider who is not part of the care team who will place the order for the plasma (CCP vs. control plasma) using a paper order that will not be part of the electronic medical record. The safety monitoring committee (SMC) will review study data, including unblinded data, to evaluate the safety, efficacy, study progress, and conduct of the study.","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04569877,Recruiting,"September 24, 2020","December 25, 2022","Severe Acute Respiratory Syndrome (SARS) Pneumonia,COVID-19 Pneumonia","Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,238
NCT04481620,Recruiting,"August 31, 2020","January 31, 2021",COVID-19,"Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1315
NCT04384250,Recruiting,"May 10, 2020","May 1, 2021",Genetic Basis of COVID-19 Infection,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:50 Years",No,50
NCT04564274,Recruiting,"October 12, 2020","September 1, 2021","Chronic Health Conditions,Older Age is Associated With Increased Pathogenicity","Other,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:1 Month,Max Age:N/A",No,120000
NCT04367662,Completed,"April 9, 2020","May 14, 2020",COVID-19,"N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,99
NCT04565249,Not yet recruiting,"September 21, 2020","October 31, 2021","Acute Respiratory Distress Syndrome,SARS-CoV-2","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,36
NCT04403581,Not yet recruiting,May 2020,June 2020,Covid-19,"Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:23 Years,Max Age:55 Years",No,384
NCT04456361,"Active, not recruiting","April 16, 2020","December 15, 2020","ARDS, Human,Covid-19","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,9
NCT04540406,Not yet recruiting,"October 1, 2020","March 1, 2021",Suspected or Confirmed COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:69 Years",No,100
NCT04332081,Terminated,"April 6, 2020","May 29, 2020",COVID-19,"Non-Randomized,Single Group Assignment,prospective pilot cohort study,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04391101,Not yet recruiting,June 2020,December 2021,SARS-Cov-2,"Randomized,Parallel Assignment,Open label, parallel, randomized clinical trial with stratified (center and age) patient allocation in a 2 :1 ratio (plasma: standard management) for a superiority hypothesis,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,231
NCT04410159,Completed,"June 22, 2020","July 6, 2020",COVID-19,"Randomized,Parallel Assignment,4 arms
Gargle with povidone-iodine
Gargle with essential oils
Gargle with tap water
Control,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04352608,"Active, not recruiting","April 16, 2020","December 13, 2020",COVID-19,"Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:59 Years",No,744
NCT04382781,Recruiting,May 2020,May 2020,COVID-19 Infection,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04366739,Not yet recruiting,"April 29, 2020","September 30, 2020",COVID-19,"Randomized,Parallel Assignment,Allocation: Randomized Intervention Model: Parallel Assignment
Intervention Model Description:
reCoVery is a multi-center, randomized, single-blind, standard care-controlled (1:1) pilot clinical study to explore the efficacy and safety of chlorpromazine (CPZ) in the treatment of adult subjects with COVID-19-moderate type (WHO-OSCI 3-5).,Treatment,Single (Outcomes Assessor),The evaluator of the primary endpoint and secondary endpoints relating to the clinical efficacy of CPZ and the evaluator of the biological and radiological effects of the CPZ will be maintained blindly throughout their duration of inclusion. This evaluator will collect clinical data, biological data, and imaging data without knowing the drug treatments delivered to patients.
The radiologists responsible for calculating the parenchymal damage score on the thoracic CT scan will be blind to the patient delivered drugs.
The biologists responsible for carrying out the analyzes on the biobank will be blind to the patient delivered drugs.
The biostatistician responsible for statistical study analysis will be kept blind to the drugs delivered to the subjects.","gender:All,Min Age:18 Years,Max Age:N/A",No,40
NCT04494399,Recruiting,"July 29, 2020","August 1, 2022",Covid19,"Randomized,Parallel Assignment,open label randomised controlled trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,96
NCT04497194,Recruiting,"March 1, 2020","September 30, 2020",Coronavirus Disease 2019,"Cohort,Other","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,500
NCT04471519,"Active, not recruiting","July 13, 2020","June 30, 2021","COVID-19,SARS-CoV-2 Infection","Randomized,Parallel Assignment,Prevention,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:12 Years,Max Age:65 Years",No,755
NCT04374487,"Active, not recruiting","May 9, 2020","August 9, 2021",COVID 19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:85 Years",No,100
NCT04341519,Recruiting,"April 6, 2020","December 31, 2021","Corona Virus Infection,Post-traumatic Stress Disorder","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1464
NCT04362943,Recruiting,"April 20, 2020","July 31, 2020",COVID-19,"Other,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:70 Years,Max Age:N/A",No,576
NCT04527601,Completed,"August 21, 2020","September 13, 2020","Extreme Prematurity,Covid19","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:22 Weeks,Max Age:28 Weeks",No,885
NCT04361422,Not yet recruiting,"December 1, 2020",December 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:40 Years",No,300
NCT04469647,Enrolling by invitation,"July 19, 2020","June 15, 2021",COVID 19,"Cohort,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1200
NCT04437875,Completed,"June 17, 2020","August 10, 2020",Preventive Immunization COVID-19,"Non-Randomized,Parallel Assignment,An open, prospective, two-stage, non-randomized, first-phase study involving healthy volunteers,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:60 Years",No,38
NCT04487574,Recruiting,"July 25, 2020",December 2020,SARS-CoV-2 Infection,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator),Tablets identical in terms of composition, appearance and labeling to XC221 tablets, but without active substance will be used as Placebo.","gender:All,Min Age:18 Years,Max Age:75 Years",No,118
NCT04514016,Recruiting,"August 12, 2020","March 31, 2021","SARS-CoV Infection,Covid19","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:3 Years,Max Age:25 Years",No,100
NCT04366219,Not yet recruiting,June 2020,"August 28, 2022","COVID,SARS-CoV 2,Lung Cancer","Other,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04374591,"Active, not recruiting","August 1, 2020","November 1, 2020","Pneumonia,Covid19","Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,180
NCT04555096,Recruiting,"September 9, 2020",December 2021,"Covid19,SARS-CoV-2 Infection","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04530539,Not yet recruiting,"September 18, 2020","December 1, 2021","Covid19,SARS-CoV Infection","Randomized,Parallel Assignment,Supportive Care,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:50 Years,Max Age:N/A",No,150
NCT04518969,Recruiting,"May 3, 2020","December 1, 2020",Covid19,"Randomized,Parallel Assignment,Pilot randomized controlled study,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,24
NCT04401540,Recruiting,"May 1, 2020","December 30, 2020","COVID-19,Neonatal Disease,Healthy","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:28 Days",No,90
NCT04334148,Recruiting,"April 22, 2020",October 2020,COVID-19,"Randomized,Parallel Assignment,Double blind, placebo-controlled, randomized clinical trial.,Prevention,Triple (Participant, Care Provider, Investigator),Double-blind","gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04368299,Recruiting,"May 1, 2020","December 31, 2021",SLE,"Randomized,Parallel Assignment,Health Services Research,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,150
NCT04382469,Completed,"February 1, 2020","May 1, 2020",COVID,"Case-Crossover,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,48
NCT04570397,Not yet recruiting,November 2020,November 2021,"Covid19,Thrombotic Microangiopathies,Acute Kidney Injury","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:85 Years",No,32
NCT04380766,Completed,"January 1, 2019","July 31, 2020",Pancreatic Cancer,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,730
NCT04505774,Recruiting,"September 4, 2020",December 2021,Covid19,"Randomized,Single Group Assignment,This is an adaptive design,Treatment,None (Open Label),There will be independent masked adjudicators.","gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04367207,Recruiting,"May 1, 2020","December 31, 2020",Severe Acute Respiratory Syndrome Coronavirus 2,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04354831,Recruiting,"May 11, 2020","May 1, 2023",COVID-19,"Non-Randomized,Parallel Assignment,131 patients in 2 cohorts (ICU cohort and a hospitalized non-ICU cohort),Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,131
NCT04532411,"Active, not recruiting","March 1, 2020","September 30, 2020","SARS-CoV Infection,Respiratory Viral Infection,Personal Protective Equipment,Covid19","Other,Other","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,25000
NCT04359992,Not yet recruiting,"April 17, 2020","May 1, 2021",COVID-19 Infection,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04363593,Recruiting,"May 4, 2020","November 4, 2020",Corona Virus Infection,"Non-Randomized,Parallel Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,3200
NCT04409249,Completed,"March 15, 2020","May 28, 2020","COVID-19,Prognostic Factors,Pregnancy","Other,Retrospective","sampling_method:Probability Sample,gender:Female,Min Age:18 Years,Max Age:45 Years",No,155
NCT04481529,Not yet recruiting,"August 15, 2020","January 15, 2021",Infection Viral,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04466683,Recruiting,"August 28, 2020","December 31, 2022","Covid-19,Sars-CoV2,Pneumonia","Randomized,Parallel Assignment,Subjects will be randomized 2:1 to receive radiation therapy (2 different doses) or control (no radiation). Sixty subjects will be enrolled to 3 arms and the best dose chosen after enrolling 60 subjects. Randomization of an additional 40 subjects will be randomized 2:1 to receive radiation therapy (best dose) versus control with no radiation.,Treatment,None (Open Label)","gender:All,Min Age:50 Years,Max Age:N/A",No,100
NCT04451239,Not yet recruiting,"June 30, 2020",July 2020,Keratonjunctivitis,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,12
NCT04371601,"Active, not recruiting","March 1, 2020","December 31, 2022",COVID-19 Pneumonia,"Randomized,Parallel Assignment,Control group: conventional symptomatic treatments such as antiviral (oseltamivir), hormones, oxygen therapy, mechanical ventilation and other supportive therapies; Experimental group: On the basis of the above-mentioned conventional symptomatic treatment and supportive therapy, umbilical cord mesenchymal stem cells were given at 106 / Kg body weight / time, once every 4 days for a total of 4 times. Peripheral intravenous infusion was given within 3 days of first admission.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,60
NCT04380688,"Active, not recruiting","June 13, 2020","November 19, 2020",COVID-19,"Randomized,Parallel Assignment,Study will consist of two arms Arm 1 is acalabrutinib + best supportive care or Arm 2 is best supportive care alone,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:130 Years",No,61
NCT04539834,"Active, not recruiting","May 1, 2020","October 1, 2020",Electrolyte Imbalance,"Case-Only,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,52
NCT04356365,Completed,"March 31, 2020","April 7, 2020","Depression,Generalized Anxiety,Adherence to Non-pharmacological Epidemiological Interventions (NPIs)","Other,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,10084
NCT04397588,Recruiting,"April 21, 2020","October 21, 2020","ARDS Related to Severe Acute Respiratory Syndrome-Coronavirus (SARS-CoV) 2,Acute Refractory Heart Failure Related to SARS-CoV 2","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,300
NCT04386369,Completed,"April 15, 2020","June 1, 2020","ARDS,COVID19","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,17
NCT04352764,Recruiting,"March 27, 2020","January 31, 2021",Covid19,"Case-Control,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,5000
NCT04400448,Not yet recruiting,"June 1, 2020","October 31, 2020",Covid-19,"Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04411628,Completed,"May 28, 2020","August 26, 2020",COVID-19,"Randomized,Parallel Assignment,Basic Science,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:75 Years",No,24
NCT04362059,Recruiting,"June 18, 2020","November 16, 2021",Respiratory Infections,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,24
NCT04387968,Recruiting,"August 24, 2020","March 24, 2021",Coronavirus Infection,"Ecologic or Community,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:65 Years",No,5000
NCT04556565,Recruiting,"May 8, 2020",May 2021,"Covid19,Mental Health Disorder,Mental Health Conditions","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,16000
NCT04339998,Recruiting,"April 15, 2020",October 2020,"Coronavirus Infection,COVID,Covid-19,SARS-CoV-2","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04366830,No longer available,N/A,N/A,N/A,N/A,"gender:All,Min Age:18 Years,Max Age:N/A",N/A,N/A
NCT04578197,Recruiting,"August 18, 2020",November 2022,Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04459819,Recruiting,"March 1, 2020","September 30, 2020",COVID-19,"Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,80
NCT04348500,"Active, not recruiting","April 24, 2020","March 31, 2021",COVID19,"Randomized,Parallel Assignment,We propose the administration of a blinded dose of an investigational product (IP) (clazakizumab or placebo[0.9% saline]) in patients with COVID-19 disease and signs of pulmonary involvement who have not yet required mechanical ventilation and/or ECMO. If a patient progresses to mechanical ventilation and/or ECMO or develops clinical signs of deteriorating COVID-19 disease, and there are no treatment related serious adverse events(SAEs), within the initial 14 day period after the first dose of the IP, at the discretion of the investigator or treating physician, open-label clazakizumab 25mg IV X 1 dose may be administered. A minimum of 24 hours should elapse between the first dose of IP and this dose of open-label clazakizumab. The patient will remain blinded as to the identity of the IP administered in the first dose.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Blinded IP (clazakizumab or placebo) will be given initially, followed by the option of an open label dose of clazakizumab within the first 14 days of initial IP administration","gender:All,Min Age:18 Years,Max Age:100 Years",No,17
NCT04505592,Recruiting,"September 25, 2020",April 2021,"COVID-19,Respiratory Failure,ARDS","Randomized,Sequential Assignment,Subjects will be randomized in a 2:1 ratio to treatment or control in blocks of 15, performed twice per dose (low and high) with randomization stratified by site.,Treatment,Triple (Participant, Care Provider, Investigator),Patients and study investigators will be blinded to subject treatment.","gender:All,Min Age:18 Years,Max Age:75 Years",No,60
NCT04459364,Recruiting,"June 1, 2020","July 10, 2020","Hypertension, Pulmonary,Right Ventricular Overload,COVID","Cohort,Other","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04359875,Not yet recruiting,April 2020,December 2020,"Cardiovascular Diseases,Mental Disorder","Randomized,Parallel Assignment,Cluster randomized trial with 2 subtrials : COVIQuest_CV and COVIQuest_MH.
COVIQuest_CV involves patients ≥ 70 years old suffering from chronic cardiovascular disease; and COVIQuest_MH involves patients suffering from a mental health disease.
As a note, both sub-trials are two-parallel group cluster randomized trials. Clusters will be defined as practices. Practices will be randomized into two groups A and B. For practices in group A: their CV patients constitute the experimental group for the COVIQuest_CV trial, their MH patients constitute the control group for the COVIQuest_MH trial. For practices in group B: their CV patients constitute the control group for the COVIQuest_CV trial, their MH patients constitute the experimental group for the COVIQuest_MH trial.,Health Services Research,None (Open Label)","gender:All,Min Age:18 Years,Max Age:110 Years",No,22000
NCT04359680,Recruiting,"May 13, 2020","December 31, 2020","COVID-19,Viral Respiratory Illnesses","Randomized,Parallel Assignment,Prevention,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:120 Years",No,800
NCT04331366,Recruiting,"April 8, 2020",August 2020,COVID-19,"N/A,Single Group Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,5
NCT04339387,Recruiting,"March 1, 2020","April 15, 2020","Coronavirus,Coronavirus Sars-Associated as Cause of Disease Classified Elsewhere","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1500
NCT04383457,Recruiting,"June 15, 2020",December 2020,Coronavirus Infections,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04418947,Completed,"June 15, 2020","July 17, 2020",Communication Research,"Randomized,Factorial Assignment,Randomized, double-blind, factorial design,Other,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:N/A,Max Age:N/A",No,11120
NCT04278963,Suspended,"February 27, 2020",January 2021,"CoVID-19,Chinese Medicine","Randomized,Parallel Assignment,Treatment,Double (Participant, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04390594,Recruiting,"August 13, 2020","August 12, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,186
NCT04381052,Not yet recruiting,May 2020,"August 1, 2020",COVID-19,"Randomized,Parallel Assignment,This is a randomized, double-blind, placebo-controlled, adaptive seamless Phase II/III design (ASD). The investigators propose the administration of an investigational drug in patients with high predicted short-term mortality secondary to COVID-19 disease. Patients will be enrolled and randomly assigned in a 1:1 ratio to two study arms that will receive clazakizumab at a dose of 25 mg or placebo.,Treatment,Double (Participant, Investigator),This study is double-blind and therefore neither the Investigator, the subject, the Sponsor and its representatives, nor other designated study site personnel involved in running of the study will be aware of the identification of the investigational drug administered to each subject.","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04519320,Recruiting,"May 18, 2020","August 18, 2025",Sars-CoV2,"N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:79 Years",No,140
NCT04422977,Not yet recruiting,"June 8, 2020","June 30, 2020",Sars-CoV2,"N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:70 Years",No,900
NCT04390464,Recruiting,"May 8, 2020","May 1, 2022",COVID19,"Randomized,Parallel Assignment,TACTIC-R is a randomised, parallel arm, open-label platform trial.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,1167
NCT04308187,Not yet recruiting,"March 11, 2020",March 2022,"Stress, Psychological","Cohort,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,50000
NCT04333225,"Active, not recruiting","April 3, 2020","July 30, 2020",COVID-19,"Non-Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,228
NCT04374903,Not yet recruiting,"May 1, 2020","September 1, 2020",COVID-19 Patients,"Randomized,Parallel Assignment,Subjects who are enrolled in the study will be randomly assigned to any of the study arms, A or B
Study Arm A (HCQ & AZ): Subjects will receive HCQ 600mg PO X 10 days and AZ PO 250mg DAILY X 10 days.
Study Arm B (HCQ+SIR): Subjects will receive HCQ 600mg PO X 10 days and SIR 4mg PO X 1 day then 2mg PO DAILY X 9 days,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,58
NCT04448145,Recruiting,"March 26, 2020","March 1, 2021","COVID-19,Corona Virus Infection,SARS-CoV 2","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:7 Years,Max Age:N/A",No,250
NCT04321369,Completed,"March 9, 2020","March 23, 2020","Infections, Respiratory,Fever,Cough","Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,533
NCT04473274,Recruiting,"May 21, 2020","June 1, 2021","Coronavirus Infection,Diabetes","Non-Randomized,Parallel Assignment,Matching cohort,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04542343,Not yet recruiting,"October 1, 2020","September 30, 2021",Coronavirus,"N/A,Single Group Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:65 Years,Max Age:N/A",No,265
NCT04492527,Recruiting,"July 28, 2020","July 31, 2021","Chronic Disease,Aging,Aging Problems,Health Behavior,Multiple Chronic Conditions,Chronic Illness,Chronic Illnesses, Multiple,Healthy Lifestyle,Healthy Aging,Aging Well,Healthy Life Style,Self-management,Self Care","N/A,Single Group Assignment,Prevention,None (Open Label)","gender:All,Min Age:65 Years,Max Age:N/A",No,75
NCT04408365,Not yet recruiting,"June 1, 2020","May 31, 2021","COVID,Shock","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,82
NCT04490850,Recruiting,"July 15, 2020","July 15, 2021","Coronavirus Infection,Severe Acute Respiratory Syndrome,SARS-CoV Infection,Covid19","N/A,Single Group Assignment,Prevention,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,1500
NCT04475107,Recruiting,July 2020,February 2021,COVID-19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Investigator, Outcomes Assessor)","gender:All,Min Age:19 Years,Max Age:N/A",No,76
NCT04442386,Not yet recruiting,"June 22, 2020","July 13, 2020",Parental Burnout,"Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1500
NCT04369066,Recruiting,"April 28, 2020","April 28, 2021",Volunteers From the Institute Curie and Institute Pasteur Staff Who Are Not Showing Active SARS-CoV-2 Infection,"N/A,Single Group Assignment,Health Services Research,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,2800
NCT04442152,Enrolling by invitation,June 2020,August 2020,"Gender Relations,Partner Communication,Division of Carework,Couple Conflict,Stress","Randomized,Parallel Assignment,Note that we are collecting new data from participants previously randomly assigned to intervention and control arms.,Prevention,Single (Outcomes Assessor)","gender:All,Min Age:26 Years,Max Age:40 Years",No,1000
NCT04326036,Enrolling by invitation,"March 25, 2020","December 31, 2021","Pulmonary Alveolar Proteinosis,COPD,Idiopathic Pulmonary Fibrosis,Viral Pneumonia,Coronavirus Infection,Interstitial Lung Disease","Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:90 Years",No,10
NCT04551274,Not yet recruiting,"October 1, 2020","November 30, 2020","Mood,Emotional Stress","Randomized,Parallel Assignment,Supportive Care,Single (Outcomes Assessor),The data analysts and Outcomes Assessors will be blinded to the group labels","gender:All,Min Age:19 Years,Max Age:N/A",No,20
NCT04558424,Not yet recruiting,"October 1, 2020","September 1, 2021",Covid19,"Randomized,Parallel Assignment,Criteria
Inclusion Criteria:
≥ 18 years presenting symptoms who test positive for COVID-19
Moderate to severe patients obtained consent
Hypoxic respiratory failure (saturation <90% on air at rest or increasing oxygen requirement)
Chest examination findings of bilateral crackles on auscultation or chest x-ray showing bilateral infiltrates
C-Reactive Protein > 50mg/L
women of childbearing potential who meet the above and have a negative pregnancy test.
Exclusion Criteria:
Pregnant women: Current known pregnancy positive pregnancy test.
Lactating women.
Documented history of mental illnesses
Multi-organ failure
Severe ARDS (requiring ventilator support on presentation in the form of invasive or non-invasive ventilation)
Septic Shock
Drug allergy/intolerance,Supportive Care,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Immediately after randomization, random numbers of the two sets will assigned as patients code number. One set will be designated as intervention group and another group will placebo group. Two sets of code number that belongs to the intervention group and placebo group will be written with patient's id number. this total procedure will be conducted by the person unrelated to this research. Thus, the participants, caregiver, outcome assessor and the analyst, who require being blind for such study will effectively blind","gender:All,Min Age:18 Years,Max Age:70 Years",No,50
NCT04387838,Recruiting,"May 14, 2020","July 31, 2020",Sars-CoV2,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:62 Years",No,900
NCT04431908,Recruiting,"June 15, 2020","October 1, 2020",COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,250
NCT04427345,Recruiting,"March 1, 2020","May 31, 2021",covid19,"Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04540120,Recruiting,"September 25, 2020",February 2021,"Covid19,Cytokine Release Syndrome","Randomized,Parallel Assignment,Subjects will be assigned to receive either dapansutrile capsules or placebo capsules in a 1:1 ratio.,Treatment,Triple (Participant, Care Provider, Investigator),This is a randomized, blinded, placebo-controlled study. Treatment allocation (to active or placebo treatment groups) will be blinded to all study participants, personnel, and investigators. Only the drug labeling personnel, unblinded pharmacist and DMC members may be unblinded to the treatment assignment. Also, in the event of an emergency, an unblinding envelope can be opened unmasking the treatment assignment to the PI.","gender:All,Min Age:18 Years,Max Age:N/A",No,80
NCT04388644,Recruiting,"February 20, 2020","May 30, 2020",Corona Virus Infection,"Case-Only,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:20 Years,Max Age:65 Years",No,300
NCT04477213,Not yet recruiting,"August 1, 2020","September 20, 2020","COVID19,Healthcare Workers","Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:70 Years",No,600
NCT04358588,No longer available,N/A,N/A,N/A,N/A,"gender:All,Min Age:18 Years,Max Age:95 Years",N/A,N/A
NCT04453553,Not yet recruiting,"July 2, 2020","September 28, 2020",COVID,"Randomized,Parallel Assignment,randomised cluster trial of care homes,Diagnostic,None (Open Label),No masking will be used as the study arms have different testing patterns","gender:All,Min Age:18 Years,Max Age:130 Years",No,50
NCT04349982,Recruiting,"April 8, 2020","July 31, 2020","Risk Factor, Cardiovascular,Covid19,Critical Illness,Course Illness","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04484597,Recruiting,"March 15, 2020","September 15, 2020",Positive COVID-19 by PCR,"Case-Control,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,100
NCT04555005,Completed,"March 10, 2020","April 26, 2020","Mindfulness,COVID-19,Healthcare Worker","N/A,Single Group Assignment,Supportive Care,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,1000
NCT04488471,Recruiting,"June 30, 2020","June 30, 2022",Inflammatory Bowel Diseases,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:16 Years,Max Age:N/A",No,232
NCT04487639,Recruiting,"July 10, 2020",July 2021,"Sperm Preservation in Oncological Patients,Fertility,Cryopreservation","N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:Male,Min Age:18 Years,Max Age:60 Years",No,250
NCT04528368,Recruiting,"August 18, 2020","December 31, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,60
NCT04361500,Recruiting,"April 15, 2020","October 1, 2021",COVID-19,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:99 Years",No,100
NCT04454333,Completed,"June 3, 2020","June 20, 2020","Infection,COVID,Pain","Cohort,Retrospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:95 Years",No,466
NCT04351906,Recruiting,"May 3, 2020","October 1, 2021","ARDS,Hypercapnic Respiratory Failure,AKI","N/A,Single Group Assignment,ECCO2R,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04421391,Recruiting,"June 8, 2020","November 8, 2020","Covid19,Coronavirus,SARS-CoV 2","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:120 Years",No,500
NCT04386265,Enrolling by invitation,"May 11, 2020","May 11, 2022",COVID-19,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04519437,Recruiting,"July 26, 2020","October 25, 2021","Healthy,Chronic Stable Illness","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:90 Years",No,940
NCT04556513,Recruiting,"September 18, 2020",November 2021,"Covid19,ARDS,Functional Recovery","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04497311,Recruiting,"June 15, 2020","April 30, 2022","SARS-CoV-2,Covid19,H1N1 Influenza,Computed Tomography","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,100
NCT04415151,Recruiting,"July 29, 2020","March 31, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:65 Years",No,60
NCT04542408,Not yet recruiting,"September 1, 2020","September 30, 2021",Covid19,"Randomized,Parallel Assignment,Treatment,Double (Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,172
NCT04487964,Recruiting,"January 1, 2020",January 2021,COVID-19,"Non-Randomized,Parallel Assignment,Pilot study,Prevention,None (Open Label)","gender:All,Min Age:12 Years,Max Age:65 Years",No,70
NCT04442217,Not yet recruiting,"June 22, 2020","July 13, 2020","Adherence to WHO-advised Hygiene-related Behavior,Adherence to Viral Mitigation Protocols","Other,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,4000
NCT04370223,Not yet recruiting,"May 25, 2020","December 25, 2020",COVID-19 Pneumonia,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:90 Years",No,208
NCT04552379,Not yet recruiting,September 2020,December 2021,"SARS-CoV Infection,Interferon,Covid19","Randomized,Parallel Assignment,A prospective, cluster randomised trial of interferon versus standard of care. Index cases will be identified from databases of positive COVID-19 PCR patients from the virology lab,('Fever') clinics, outpatient clinics and hospital emergency room visits for possible COVID-19. Household contacts will be identified via the index cases and will be approached with the consent of the index case.
Randomisation: Households will be randomised to receive IFN or standard of care (as recommended by the Public Health Department).
Trial population: Index cases positively infected with SARS-CoV-2 and their exposed household contacts. Index cases will be recruited from databases of individuals with confirmed COVID-19 identified from COVID-19 ('Fever') clinics and emergency room visits in Santiago, Chile.
Eligibility criteria: Households will be randomised only if cases and at least one treatment-eligible household contact meets all the inclusion criteria and none of the exclusion criteria.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:79 Years",No,1240
NCT04537806,Not yet recruiting,November 2020,October 2021,"Acute Respiratory Distress Syndrome,COVID-19","Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04494776,Recruiting,"May 21, 2020","April 2, 2022","SARS-CoV-2 Infection,Kidney Transplant Infection","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,500
NCT04425759,Recruiting,"June 8, 2020","June 30, 2021","Covid19,Corona Virus Infection,SARS-CoV 2,COVID","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2400
NCT04521400,Not yet recruiting,"August 20, 2020","September 11, 2020",Covid19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:100 Years",No,100
NCT04358627,Not yet recruiting,"April 15, 2020","June 30, 2020","Acute Respiratory Distress Syndrome,Inflammation,Dexmedetomidine,Cytokine Storm,Delirium, Emergence","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:99 Years",No,80
NCT04376996,Recruiting,"April 20, 2020",December 2020,"COVID-19,SARS-CoV-2","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,3000
NCT04429867,"Active, not recruiting","May 7, 2020","December 7, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,700
NCT04321096,Recruiting,"April 4, 2020","May 1, 2021",Corona Virus Infection,"Randomized,Parallel Assignment,There are 2 cohorts: Cohort 1 - hospitalized patients (n=180); Cohort 2 - outpatients (n=400). All participants in the two cohorts are randomized to one of two arms,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Placebo-controlled","gender:All,Min Age:18 Years,Max Age:110 Years",No,580
NCT04372628,Recruiting,"June 1, 2020","May 1, 2021",COVID-19,"Randomized,Sequential Assignment,Blinded, multicenter, placebo-controlled randomized clinical trial,Treatment,Triple (Participant, Care Provider, Investigator),Lopinavir/Ritonavir tablets or unmatched placebo tablets","gender:All,Min Age:18 Years,Max Age:N/A",No,600
NCT04343001,Not yet recruiting,October 2020,August 2021,Covid-19,"Randomized,Factorial Assignment,2 x 2 x 2,Treatment,None (Open Label)","gender:All,Min Age:40 Years,Max Age:N/A",No,10000
NCT04348305,"Active, not recruiting","April 17, 2020","June 8, 2021","Covid-19,Hypoxia","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,1000
NCT04527458,Completed,"February 24, 2020","August 2, 2020",Covid19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,70000
NCT04373148,Recruiting,"April 8, 2020","April 30, 2022",Coronavirus,"Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:2 Years,Max Age:N/A",No,1000
NCT04469660,Recruiting,"May 18, 2020","September 30, 2020",Psychological Stress,"Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:90 Years",No,1300
NCT04346446,Completed,"April 20, 2020","May 30, 2020",COVID,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,29
NCT04530474,Not yet recruiting,"October 1, 2020","December 31, 2021",Covid19,"Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04537858,"Active, not recruiting","June 18, 2020","December 1, 2020","COVID-19,Inpatient","Randomized,Crossover Assignment,Treatment,None (Open Label)","gender:All,Min Age:20 Years,Max Age:80 Years",No,50
NCT04414618,Recruiting,"July 2, 2020","November 30, 2020",Coronavirus Infections,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:80 Years",No,40
NCT04494386,Recruiting,"July 23, 2020","November 30, 2021","Covid19,Corona Virus Infection,SARS-CoV Infection,ARDS,Coronavirus","Randomized,Parallel Assignment,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04402853,Completed,"February 1, 2020","May 20, 2020","Sars-CoV2,Tear","Case-Crossover,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04375670,Recruiting,"May 11, 2020","December 31, 2020","Liver Diseases,COVID19","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,1000
NCT04390061,Not yet recruiting,June 2020,October 2020,"Pneumonitis, Interstitial,COVID-19","Randomized,Parallel Assignment,Multicenter open label randomized controlled trial,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:65 Years",No,116
NCT04386720,Recruiting,"May 25, 2020","May 25, 2021",Acute Respiratory Distress Syndrome,"Case-Only,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,20
NCT04423692,Recruiting,"June 1, 2020","August 20, 2020",Viral Infection,"Other,Prospective","sampling_method:Probability Sample,gender:Female,Min Age:18 Years,Max Age:42 Years",No,30
NCT04363606,Recruiting,"May 27, 2020",December 2021,"Chronic Fatigue Syndrome,Intensive Care Unit,Muscle","Non-Randomized,Parallel Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:35 Years,Max Age:80 Years",No,52
NCT04536298,Not yet recruiting,"September 15, 2020","January 15, 2021",COVID-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:30 Years,Max Age:N/A",No,2700
NCT04385914,Not yet recruiting,May 2020,December 2020,Corona Virus Infection,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:Female,Min Age:18 Years,Max Age:50 Years",No,200
NCT04371419,Completed,"May 13, 2020","May 24, 2020",Coronavirus,"Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,15475
NCT04527562,Recruiting,"July 14, 2020",December 2020,Covid19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04355702,Recruiting,"March 1, 2020","December 30, 2020","Systemic Lupus Erythematosus,Covid-19","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:90 Years",No,130
NCT04416334,Recruiting,"May 25, 2020","December 31, 2020",SARS-CoV-2 Infection (COVID-19),"Randomized,Parallel Assignment,Prevention,None (Open Label)","gender:All,Min Age:70 Years,Max Age:N/A",No,1028
NCT04340479,Recruiting,"July 30, 2020",May 2022,"COVID,Trauma,Ultrasound","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,20
NCT04394377,Recruiting,"June 21, 2020",December 2020,Coronavirus Infection,"Randomized,Parallel Assignment,Treatment,Single (Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,600
NCT04325048,Not yet recruiting,April 2020,September 2021,Coronavirus Infection,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,5000
NCT04519307,"Active, not recruiting","March 1, 2020","August 31, 2020",Viral Infection,"Case-Control,Prospective","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:1 Month",No,72
NCT04382508,Enrolling by invitation,"March 22, 2020","March 21, 2021","Immune Suppression,Immune Deficiency,Infection,COVID,Children, Adult","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,1500
NCT04401371,Completed,"May 1, 2020","May 10, 2020",Distance Education Learning Environment,"Other,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,418
NCT04416009,Recruiting,"July 5, 2020","February 20, 2021","Extracellular Fluid Alteration,Corona Virus Infection","Cohort,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,52
NCT04468971,Recruiting,"September 29, 2020","September 30, 2021","COVID19,ARDS","Randomized,Parallel Assignment,Multi-center, prospective, double-blinded, placebo controlled Phase 1 randomized clinical trial.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,45
NCT04389840,Recruiting,"June 3, 2020",March 2021,"COVID-19,Acute Lung Injury,SARS-CoV-2","Randomized,Parallel Assignment,Randomized 1:1,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Double-blind","gender:All,Min Age:18 Years,Max Age:85 Years",No,524
NCT04505761,Recruiting,"August 1, 2020","January 1, 2021","Coronavirus,Post Intensive Care Unit Syndrome","N/A,Single Group Assignment,Participants are asked to use Virtual Reality as an add-on to standard physiotherapy for revalidation after COVID-19.,Treatment,None (Open Label)","gender:All,Min Age:16 Years,Max Age:N/A",No,40
NCT04418206,Not yet recruiting,"June 1, 2020","June 1, 2021",Covid 19,"N/A,Single Group Assignment,COVID-19 patients will be selected in the 4 participating centres Contact subjects and healthy volunteers will be selected only in the coordinating centre (Centre Hospitalier Universitaire de Nice),Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,300
NCT04423003,Completed,"March 1, 2020","May 15, 2020","Change; Endoscopy, COVID-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,10
NCT04311697,Recruiting,"May 15, 2020",September 2020,"Critical COVID-19 With Respiratory Failure,Acute Respiratory Distress Syndrome (ARDS),Corona Virus Infection,Acute Lung Injury","Randomized,Parallel Assignment,Multicenter trial, initially conducted at a single center with a safety/futility assessment following enrollment of 30 patients,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Randomized, placebo-controlled trial with identical drug and placebo infusion bags","gender:All,Min Age:18 Years,Max Age:100 Years",Yes,144
NCT04449380,Not yet recruiting,September 2020,June 2021,COVID-19 Virus Infection,"Randomized,Parallel Assignment,This is an interventional, monocentric, phase 2, randomized (2:1), open label, controlled clinical study,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,126
NCT04441398,Not yet recruiting,July 2020,September 2020,covid19,"Randomized,Parallel Assignment,Subjects will be randomized to receive either nitazoxanide (n=150) or placebo (n=150),Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:50 Years,Max Age:N/A",No,300
NCT04560231,Recruiting,"June 1, 2020","November 30, 2020",SARS-CoV Infection,"N/A,Single Group Assignment,Qausi-experimental,Treatment,None (Open Label)","gender:All,Min Age:15 Years,Max Age:80 Years",No,30
NCT04459247,"Active, not recruiting","June 15, 2020","September 10, 2020",COVID,"Randomized,Parallel Assignment,Treatment,Double (Participant, Care Provider)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04410692,Completed,"May 15, 2020","May 17, 2020","Health Knowledge, Attitudes, Practice","Randomized,Parallel Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,560
NCT04315298,Completed,"March 18, 2020","September 2, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,1912
NCT04408066,Recruiting,"April 30, 2020","April 30, 2022",COVID-19,"Non-Randomized,Parallel Assignment,A Sample Collection & Performance Evaluation Study.,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04532294,Recruiting,"September 8, 2020","December 31, 2020",Covid19,"Randomized,Parallel Assignment,Basic Science,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:60 Years",No,30
NCT04374019,Recruiting,"May 1, 2020",May 2021,"COVID,Sars-CoV2","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:99 Years",No,240
NCT04358640,Recruiting,"April 9, 2020","April 22, 2020","Critical Illness,Sars-CoV2,SARS Pneumonia,Coronavirus Infection,Stress Disorders, Post-Traumatic","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04396210,Recruiting,"May 14, 2020","December 31, 2020","Coronavirus,COVID,ART,Fertility Issues","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:47 Years",No,2000
NCT04328467,"Active, not recruiting","April 6, 2020",August 2020,"COVID-19,Corona Virus Infection,ARDS,Acute Respiratory Distress Syndrome","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,1500
NCT04395144,Recruiting,"May 15, 2020","December 31, 2020","Coronavirus Infection,COVID,Severe Acute Respiratory Syndrome,Respiratory Failure,Respiratory Insufficiency,Respiratory Distress Syndrome,ARDS,Lung Diseases","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,346
NCT04347876,Recruiting,"April 11, 2020","June 30, 2020","COVID-19,BCG Vaccination","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:12 Years,Max Age:80 Years",No,100
NCT04389359,Not yet recruiting,September 2020,August 2025,COVID-19,"Randomized,Parallel Assignment,PROTECT will use an innovative basket design to conduct a series of prospective, randomised comparisons in multiple vulnerable patient groups in the United Kingdom with the capabilities of assessing effects within specific patients groups, and across the pooled PROTECT cohort. Additional interventions may be added as these become available. Basket Trial design brings greater efficiency, due to running multiple comparisons within one master protocol. It also allows application of innovative Bayesian analysis methods that allow adaptive borrowing of information across populations. This will mean in the case that there is a consistent effect across populations, the trial will have greater power to find significant differences for individual patient groups.,Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,1500
NCT04479488,Recruiting,"July 27, 2020",February 2021,"Covid19,SARS-CoV Infection","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04371107,Not yet recruiting,"April 29, 2020",July 2020,"Covid19,Azithromycin,Ambulatory","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,64
NCT04487171,Recruiting,"July 21, 2020",August 2021,"Postpartum Depression,Covid19,Prevalence,Social Distance","N/A,Single Group Assignment,Other,None (Open Label)","gender:Female,Min Age:18 Years,Max Age:N/A",No,248
NCT04455308,Recruiting,"July 21, 2020","September 30, 2020","Chilblains,COVID-19","Non-Randomized,Parallel Assignment,Other,None (Open Label)","gender:All,Min Age:N/A,Max Age:N/A",No,300
NCT04356443,Recruiting,"April 15, 2020","December 31, 2020","Respiratory Failure,Ventilatory Failure,COVID-19,Pneumonia,ARDS, Human","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,500
NCT04415073,Suspended,"May 30, 2020","November 15, 2020","Coronavirus,COVID,ARDS,Cytokine Storm,Cytokine Release Syndrome","Randomized,Parallel Assignment,Treatment,Double (Participant, Care Provider)","gender:All,Min Age:18 Years,Max Age:N/A",N/A,186
NCT04519255,"Active, not recruiting","July 1, 2020","July 31, 2023",PET/CT; COVID-19; Important Organs Function; Inflammatory Lesions Outcome,"Case-Control,Cross-Sectional","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:85 Years",No,60
NCT04376593,Enrolling by invitation,"May 1, 2020",May 2022,"COVID-19,SARS-CoV-2 Infection","N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,10
NCT04387799,Completed,"May 13, 2020","June 17, 2020","Pneumonia, Viral,Pneumonia, Bacterial,Coronavirus Infection,Obstructive Lung Disease","Case-Control,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:100 Years",No,520
NCT04412018,Recruiting,"June 4, 2020",December 2020,"COVID-19,Inflammatory Response","Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,100
NCT04408040,Recruiting,"July 14, 2020","July 31, 2022",COVID,"Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,700
NCT04463628,Recruiting,"May 15, 2020","June 30, 2021","Cystic Fibrosis in Children,Cystic Fibrosis","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:14 Years,Max Age:N/A",No,1200
NCT04472078,"Active, not recruiting","June 10, 2020","July 18, 2020",SARS-CoV-2,"Cohort,Cross-Sectional","sampling_method:Probability Sample,gender:All,Min Age:14 Years,Max Age:N/A",No,873
NCT04342806,Recruiting,"April 10, 2020","December 31, 2099","Health Care Worker (HCW),COVID-19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:89 Years",No,100000
NCT04526054,Recruiting,"September 3, 2020","September 3, 2021","Olfaction Disorders,COVID-19","N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,30
NCT04321278,Completed,"March 28, 2020","June 14, 2020","Coronavirus Infections,Pneumonia, Viral","Randomized,Parallel Assignment,Intervention Group: Hydroxychloroquine + azithromycin. After randomization, Hydroxychloroquine [400mg 2x/day, 12/12h] + azithromycin [500mg 1x/day]) for 10 days. Standard treatment is according to the treatment protocol for 2019-nCoV infection.
Active Control Group: Hydroxychloroquine. After randomization, Hydroxychloroquine [400mg 2x/day, 12/12h] for 10 days. Standard treatment is according to the treatment protocol for 2019-nCoV infection.,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,440
NCT04459312,Recruiting,"June 1, 2020","September 30, 2020",Antibody COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:99 Years",No,600
NCT04370236,Not yet recruiting,July 2020,February 2021,COVID-19,"Randomized,Parallel Assignment,Placebo + Standard of Care vs. XPro1595 + Standard of Care,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,366
NCT04417335,"Active, not recruiting","April 16, 2020",May 2021,COVID-19,"Randomized,Parallel Assignment,placebo-controlled adaptive multi-centre randomized controlled trial,Prevention,Single (Participant)","gender:All,Min Age:60 Years,Max Age:N/A",No,2014
NCT04335188,Recruiting,"April 6, 2020","September 30, 2021",COVID,"Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,4000
NCT04358510,Completed,"April 1, 2020","April 17, 2020","COVID-19,Pneumonia,Mechanical Ventilation","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,114
NCT04356677,Not yet recruiting,November 2020,April 2021,COVID19,"Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04332094,Recruiting,"April 2, 2020",October 2020,COVID-19,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,276
NCT04495933,Recruiting,"July 13, 2020",September 2021,"SARS-CoV2,Covid19","Randomized,Sequential Assignment,Cohort 1: SARS-CoV-2 Sclamp vaccine 5 mcg, or placebo Cohort 2: SARS-CoV-2 Sclamp vaccine 15 mcg, or placebo Cohort 3: SARS-CoV-2 Sclamp vaccine 45 mcg, or placebo,Prevention,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:N/A",No,216
NCT04379466,Recruiting,"May 5, 2020",April 2021,COVID-19,"Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:75 Years",No,60
NCT04492904,Recruiting,"July 23, 2020","March 31, 2021",Covid19,"Case-Control,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:21 Years,Max Age:70 Years",No,5000
NCT04366271,Recruiting,"May 7, 2020","May 31, 2021",COVID,"Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:40 Years,Max Age:80 Years",No,106
NCT04423315,Completed,"June 8, 2020","July 20, 2020","Corona Virus Infection,Thromboembolic Disease","Cohort,Retrospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:99 Years",No,70
NCT04341142,Recruiting,"April 9, 2020","April 9, 2024",CoV2 Positive Caregivers,"N/A,Single Group Assignment,Diagnostic,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,550
NCT04380376,Recruiting,"April 30, 2020","October 30, 2020","COVID-19,Viral Pneumonia","Non-Randomized,Parallel Assignment,Prospective, Single-center, Open-Label, Central Assessor Blinded, Comparative Study,Treatment,Single (Outcomes Assessor),An independent central blinded assessor will be blinded to study treatment and will review the clinical response assessments. In case of a discrepancy with the Investigator's assignment of clinical response, the adjudication committee's assessment will prevail.","gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04502069,Withdrawn,August 2020,June 2021,"COVID-19,Lung Infection","N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,0
NCT04342884,Recruiting,"April 8, 2020",December 2021,"Coronavirus,COVID","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:N/A",No,150000
NCT04343729,"Active, not recruiting","April 18, 2020",September 2020,"SARS-CoV Infection,Severe Acute Respiratory Syndrome (SARS) Pneumonia","Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,416
NCT04535869,Not yet recruiting,"September 4, 2020","September 3, 2021",COVID-19,"Non-Randomized,Parallel Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04363177,Not yet recruiting,"November 1, 2020",June 2023,"Perinatal Depression,COVID19,Anxiety,PTSD,Pregnancy Related","Randomized,Parallel Assignment,Prevention,Single (Participant)","gender:Female,Min Age:18 Years,Max Age:N/A",No,300
NCT04377620,Recruiting,"May 24, 2020","September 29, 2020",COVID-19,"Randomized,Parallel Assignment,Treatment,Double (Participant, Investigator),Double blinded","gender:All,Min Age:12 Years,Max Age:N/A",Yes,500
NCT04269525,Recruiting,"February 6, 2020","December 30, 2020","Pneumonia, Viral,Pneumonia, Ventilator-Associated","N/A,Single Group Assignment,reaching the criteria of pneumonia according to Diagnosis and Clinical Management of Pneumonia caused by 2019-nCoV Infection(Trial Version 4),Prevention,None (Open Label)","gender:All,Min Age:18 Years,Max Age:80 Years",No,16
NCT04494724,Recruiting,"July 13, 2020","July 31, 2021",COVID-19 Infection,"Randomized,Parallel Assignment,This single-site, phase 2 randomized, double-blind, placebo-controlled trial is designed to administer a single dose of clazakizumab or placebo on day 0. If, after 24 hours or up to 14 days from the first infusion, the participant's condition worsens or does not improve, the investigator may elect to provide a single, open-label dose of clazakizumab regardless of the initial group assignment. All except the investigational pharmacist will remain blinded as to the initial group assignment until data lock.,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor),Blinded to all except investigational pharmacy. Only the optional second infusion, if determined necessary to administer, will be open-label. The patient and study team will remain blinded until data lock at the end of the study.","gender:All,Min Age:18 Years,Max Age:N/A",N/A,60
NCT04435028,Completed,"January 14, 2019","August 13, 2019","Breast Cancer,Iron Chelation","Other,Prospective","sampling_method:Probability Sample,gender:Female,Min Age:30 Years,Max Age:60 Years",No,111
NCT04495907,Recruiting,"August 6, 2020",March 2021,"SARS-CoV-2 Infection (Asymptomatic),SARS-CoV-2 Infection (Symptomatic)","Cohort,Other","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:80 Years",No,1000
NCT04369820,Recruiting,"March 31, 2020",November 2020,COVID-19,"N/A,Single Group Assignment,Other,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,100
NCT04371315,Recruiting,"April 27, 2020","June 30, 2022","Corona Virus Infection,Pediatric Cancer,Adult Children,Cancer","Other,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:N/A,Max Age:24 Years",No,400
NCT04404192,Not yet recruiting,November 2020,September 2021,Adjustment Disorder With Anxious Mood,"N/A,Single Group Assignment,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:75 Years",No,30
NCT04419025,Recruiting,"September 23, 2020","May 31, 2021","COVID,Sars-CoV2,SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere,Oxidative Stress","Randomized,Parallel Assignment,Participants are assigned to one of two groups in parallel for the duration of the study.
One arm is the intervention arm - those receiving N-acetylcysteine (NAC). One arm is the control group - those not receiving N-acetylcysteine (NAC).,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04575545,Not yet recruiting,October 2020,April 2022,"Covid19,Virus-HIV","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,600
NCT04382560,Completed,"May 2, 2020","May 31, 2020","Behavior, Social,Autonomic Imbalance","Randomized,Parallel Assignment,wait-list control design,Other,Double (Investigator, Outcomes Assessor)","gender:All,Min Age:20 Years,Max Age:40 Years",No,69
NCT04365595,Recruiting,"June 3, 2020",December 2020,"SARS-CoV 2,COVID","Case-Only,Prospective","sampling_method:Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,200
NCT04465604,Recruiting,"July 1, 2020",May 2021,COVID-19,"N/A,Single Group Assignment,The sample size was based on the following assumptions: Poor response rate to HTS is set at 10% or less; Good response to HTS is set at 30% or more ;One-sided Alph error probability is set to < 0.05 (i.e. p < 0.05) and Power to detect rate difference between good response and poor response to HTS is at least 80%. Using the Fleming single-arm group-sequential design (Fleming 1982) Based on these assumptions; a sample size of N=25 patients is expected to achieve a power of 84% of detecting enough activity by HTS (p<0.05 one-sided) of improving respiratory parameters of COVID19 patients. This will be achieved if the true remission rate difference between a poor and good HTS is 20%. Considering the dropout rate of 25%, a minimum of 50 patients will be enrolled. This will ensure more than 90% power to detect at least 20% positive effect of HTS,Treatment,None (Open Label)","gender:All,Min Age:18 Years,Max Age:N/A",No,50
NCT04378803,Completed,"May 13, 2020","August 4, 2020",Well Aging,"Randomized,Crossover Assignment,The wait-list control group will receive the training program at a later point.,Supportive Care,None (Open Label)","gender:All,Min Age:60 Years,Max Age:95 Years",No,53
NCT04352634,Recruiting,"April 26, 2020","December 31, 2021","Covid-19,Mental Health Disorder,Stress Disorder,Anxiety,Depression,SARS-CoV-2","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,2000
NCT04356144,Recruiting,"April 15, 2020","December 1, 2020","Disseminated Intravascular Coagulation,Critical Illness,Sars-CoV2,Viral Infection,Coagulation Disorder, Blood,Covid19","Cohort,Prospective","sampling_method:Non-Probability Sample,gender:All,Min Age:18 Years,Max Age:N/A",No,60
NCT04429763,Not yet recruiting,July 2020,November 2020,COVID-19,"Randomized,Parallel Assignment,It will be included 30 patients, randomly assigned by centralized electronic sequence of assignation, for the application of a single dosis of 1*10^6 cells/Kg or placebo,Treatment,Triple (Participant, Care Provider, Investigator)","gender:All,Min Age:18 Years,Max Age:79 Years",No,30
NCT04529525,Recruiting,"August 19, 2020","January 31, 2021",Covid19,"Randomized,Parallel Assignment,Treatment,Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)","gender:All,Min Age:18 Years,Max Age:N/A",No,500