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What's the point of removing genes with identical identifiers? #271

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shelkmike opened this issue Jun 2, 2023 · 0 comments
Open

What's the point of removing genes with identical identifiers? #271

shelkmike opened this issue Jun 2, 2023 · 0 comments

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@shelkmike
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I do the following analysis:
I have a complete list of genes from a modern genome. Also, I have a complete list of genes from an ancestor of this species (computationally reconstructed) that lived a million years ago. I perform a GO term enrichment analysis between these two gene sets using the option "--compare". GOATOOLS removes identical gene identifiers from the analysis ("removed 19350 overlapping items"). Why does GOATOOLS do this? Doesn't it make results incorrect?

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