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gene sets score and gsva #276

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wangjiawen2013 opened this issue Sep 6, 2024 · 0 comments
Open

gene sets score and gsva #276

wangjiawen2013 opened this issue Sep 6, 2024 · 0 comments

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@wangjiawen2013
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Hi,
In single cell data analysis, we usually score a set of genes. The score is the average expression of a set of genes subtracted with the average expression of a reference set of genes: https://scanpy.readthedocs.io/en/1.9.x/generated/scanpy.tl.score_genes.html

I feel it's function is a bit similar with gsva. Which one is better to be a representation of cell cluster gene signature ?
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