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config.yml
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# names of all samples and paths to their count matrices
data:
Rat_Amygdala_787A_all_seq:
counts: data/snRNA/Rat_Amygdala_787A_all_seq/outs/filtered_feature_bc_matrix/matrix.mtx.gz
Rat_Opioid_HS_1_premrna:
counts: data/snRNA/Rat_Opioid_HS_1_premrna/outs/filtered_feature_bc_matrix/matrix.mtx.gz
Rat_Opioid_HS_2_premrna:
counts: data/snRNA/Rat_Opioid_HS_2_premrna/outs/filtered_feature_bc_matrix/matrix.mtx.gz
Rat_Opioid_HS_3_premrna:
counts: data/snRNA/Rat_Opioid_HS_3_premrna/outs/filtered_feature_bc_matrix/matrix.mtx.gz
Rat_Opioid_HS_4_premrna:
counts: data/snRNA/Rat_Opioid_HS_4_premrna/outs/filtered_feature_bc_matrix/matrix.mtx.gz
# name of sample(s) to use for NB parameter estimation
sample: Rat_Amygdala_787A_all_seq
# simulation parameters
params:
replicates: [1,3,5,7,10]
cells: 5000
effects: [1.25, 1.5, 1.75, 2]
alpha: 0.05
nGenes: 10000
pctDegs: 0.05
nSims: 15
test: wilcox
sample_variable: replicates
# path to directory to save output files
out: out