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Library to create discrete Functional Tissue Units

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ABI-Software/ftuutils

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FTUUtils

A python library to create Functional Tissue Units using celltype models and their interconnection information. Library was developed to support the NZ MBIE 12 Labours project.

Context

Modelling the human physiology is a complex task. The complexity is not just limited to characterising the physiological processes in a quantifiable framework, but managing the models, connecting them and reusing them to represent the multiscale, spatio-temporal processes. Functional Tissue Units (FTU) provide a concept to modularize physiology, develop models and integrate them in a hierarchical and causally tractable manner. Futher details regarding FTUs, modelling approach and functionality provided by this library are available in the TechnicalReport. A workflow create FTU from given interconnection of cells, their dynamics is available as a jupyter notebook.

Support

Users/Developers can report issues, request enhancements and features through github.