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feat: add tga cnvkit to gens #1448

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merged 65 commits into from
Oct 11, 2024
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e6516d6
add gens functionality to tga
mathiasbio Jun 14, 2024
7f6e521
add gens inputs
mathiasbio Jun 14, 2024
24e41a9
add gens gnomad af to tga
mathiasbio Jun 14, 2024
cdbe43f
black
mathiasbio Jun 14, 2024
f262919
fix
mathiasbio Jun 14, 2024
c2aafb9
fix
mathiasbio Jun 14, 2024
cc9e506
fix
mathiasbio Jun 17, 2024
d471395
fix
mathiasbio Jun 17, 2024
05bd3ae
fix
mathiasbio Jun 17, 2024
6868556
doc strings and named args
mathiasbio Jun 17, 2024
b03a9f0
black
mathiasbio Jun 17, 2024
582cfb0
changelog
mathiasbio Jun 17, 2024
e9c4c7f
bug fix
mathiasbio Jun 17, 2024
8f88da7
fix
mathiasbio Jun 17, 2024
4a4671e
lower padding
mathiasbio Jun 17, 2024
5bcf768
add tumor purity adjustment to gens cov file
mathiasbio Jun 18, 2024
acde38f
typehints
mathiasbio Jun 19, 2024
ed4c018
black
mathiasbio Jun 19, 2024
a108a0e
fix pytests
mathiasbio Jun 19, 2024
99d3d57
update purity adjustment formula
mathiasbio Jun 28, 2024
bf57f92
Merge branch 'develop' of github.com:Clinical-Genomics/BALSAMIC into …
mathiasbio Jun 28, 2024
d69c3c7
merge develop
mathiasbio Jun 28, 2024
44f25e1
m conflict
mathiasbio Jun 28, 2024
9335478
m conflict
mathiasbio Jun 28, 2024
5768116
adjust formula
mathiasbio Jul 15, 2024
6433887
add round
mathiasbio Jul 15, 2024
f3a2c66
code review
mathiasbio Jul 23, 2024
2de2692
fix merge conflicts
mathiasbio Jul 23, 2024
2b91865
fix bug
mathiasbio Jul 24, 2024
821bbd3
float
mathiasbio Jul 24, 2024
6aa5510
comment out purity and ploidy adjustment
mathiasbio Jul 24, 2024
f703189
adjust purity and ploidy
mathiasbio Jul 25, 2024
8994fc8
bug fix
mathiasbio Jul 25, 2024
11be7bf
remove purity and ploidy adjustment
mathiasbio Jul 25, 2024
3d44b03
new threads
mathiasbio Jul 29, 2024
b484670
return purity adjustment
mathiasbio Jul 31, 2024
1fac876
code review
mathiasbio Jul 31, 2024
9688e3d
new purity and ploidy formula from PureCN
mathiasbio Aug 1, 2024
8d80a75
merge pon repo
mathiasbio Aug 2, 2024
3abae1b
fix pytests
mathiasbio Aug 2, 2024
ce95786
black
mathiasbio Aug 2, 2024
d736f7c
Merge branch 'update_cnvkit_pons' of github.com:Clinical-Genomics/BAL…
mathiasbio Aug 8, 2024
4f7cf28
Merge branch 'update_cnvkit_pons' into cnvkit_to_gens
mathiasbio Aug 8, 2024
8f32eac
Merge branch 'update_cnvkit_pons' of github.com:Clinical-Genomics/BAL…
mathiasbio Aug 9, 2024
ca32fea
Merge branch 'update_cnvkit_pons' into cnvkit_to_gens
mathiasbio Aug 9, 2024
0c99f60
Merge branch 'update_cnvkit_pons' of github.com:Clinical-Genomics/BAL…
mathiasbio Aug 9, 2024
f5eebd6
Merge branch 'update_cnvkit_pons' into cnvkit_to_gens
mathiasbio Aug 9, 2024
8a40907
Merge branch 'update_cnvkit_pons' of github.com:Clinical-Genomics/BAL…
mathiasbio Aug 9, 2024
254c6a8
Merge branch 'update_cnvkit_pons' into cnvkit_to_gens
mathiasbio Aug 9, 2024
42c314a
Merge branch 'update_cnvkit_pons' of github.com:Clinical-Genomics/BAL…
mathiasbio Aug 9, 2024
e3f54f7
Merge branch 'update_cnvkit_pons' into cnvkit_to_gens
mathiasbio Aug 9, 2024
6030b87
add io test
mathiasbio Aug 13, 2024
604f059
add new test
mathiasbio Aug 13, 2024
92b5c4d
Merge branch 'update_cnvkit_pons' of github.com:Clinical-Genomics/BAL…
mathiasbio Aug 15, 2024
2a07bb1
Merge branch 'update_cnvkit_pons' into cnvkit_to_gens
mathiasbio Aug 15, 2024
3f6b529
Merge branch 'update_cnvkit_pons' of github.com:Clinical-Genomics/BAL…
mathiasbio Sep 10, 2024
9569ebd
Merge branch 'update_cnvkit_pons' into cnvkit_to_gens
mathiasbio Sep 10, 2024
b86d6f4
remove purity adjustment
mathiasbio Oct 10, 2024
139c11e
black
mathiasbio Oct 10, 2024
7e567fd
add pytest
mathiasbio Oct 10, 2024
ce98baa
black
mathiasbio Oct 10, 2024
cf739dc
clean up
mathiasbio Oct 10, 2024
7138553
clean up
mathiasbio Oct 10, 2024
1e230bb
return tiddit
mathiasbio Oct 10, 2024
a420abb
fix code smells
mathiasbio Oct 10, 2024
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new threads
mathiasbio committed Jul 29, 2024
commit 3d44b03941eb50ef6c7be1a889535db9da914854
4 changes: 4 additions & 0 deletions BALSAMIC/constants/cluster_analysis.json
Original file line number Diff line number Diff line change
@@ -156,6 +156,10 @@
"time": "24:00:00",
"n": 36
},
"sentieon_DNAscope_gnomad_tga": {
"time": "24:00:00",
"n": 12
},
"sentieon_TNhaplotyper": {
"time": "24:00:00",
"n": 36
Original file line number Diff line number Diff line change
@@ -112,7 +112,7 @@ else:
benchmark:
Path(benchmark_dir,"sentieon_DNAscope_gnomad_{sample}.tsv").as_posix()
threads:
get_threads(cluster_config,"sentieon_DNAscope_gnomad")
get_threads(cluster_config,"sentieon_DNAscope_gnomad_tga")
message:
"Calling germline variants on positions in Gnomad AF > 0.05 using Sentieon DNAscope for {params.sample}"
shell:

Unchanged files with check annotations Beta

def read_csv(csv_path: str, delimeter: str) -> List[dict]:
"""Read data from a csv file."""
with open(csv_path, mode='r') as csv_file:
csv_reader = csv.DictReader(csv_file, delimiter=delimeter)
return [row for row in csv_reader]

Check warning on line 74 in BALSAMIC/utils/io.py

Codecov / codecov/patch

BALSAMIC/utils/io.py#L72-L74

Added lines #L72 - L74 were not covered by tests
def read_yaml(yaml_path: str) -> dict:
"""Read data from a yaml file."""