Calibration of association tests

[aron0093]

Most tests (e.g. covariate association, perturbation association) give highly inflated significance (very low p-values) under typical thresholds (e.g. 0.05). We need to implement methods to calibrate the output of these tests against appropriate null p-value distributions.

Separately, reporting log2FC would also help interpretation as well as compared to using test statistics. In the dashboard we should prioritize reporting log2FC.