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Update README.md
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thorstenwagner authored Sep 29, 2023
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Expand Up @@ -13,12 +13,10 @@ AlphaMissense allows you to identify regions in your amino acid chain that are c



2. It creates a modified PDB file where the temperature factor is replaced by the pathogencity predicted by AlphaMissense that allows you to visualize the effect with Chimerax, like [Figure 3E](https://www.science.org/doi/10.1126/science.adg7492#F3) of the paper:
2. It creates a modified PDB file where the temperature factor (bfactor) is replaced by the pathogencity predicted by AlphaMissense that allows you to visualize the effect with Chimerax, like [Figure 3E](https://www.science.org/doi/10.1126/science.adg7492#F3) of the paper:

<img src="resources/img/3e.jpeg" width="400">

It does so by replacing the bfactor in the PDB.

## How to install

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## Contributions

This script was developed in collaboration with Tobias Raisch
This script was developed in collaboration with Tobias Raisch

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