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The California Cooperative Oceanic Fisheries Investigations (CalCOFI) are a unique partnership of the California Department of Fish & Wildlife, NOAA Fisheries Service and Scripps Institution of Oceanography. The organization was formed in 1949 to study the ecological aspects of the sardine population collapse off California. Today our focus has shifted to the study of the marine environment off the coast of California, the management of its living resources, and monitoring the indicators of El Nino and climate change. CalCOFI conducts quarterly cruises off southern & central California, collecting a suite of hydrographic and biological data on station and underway. Data collected at depths down to 500 m include: temperature, salinity, oxygen, phosphate, silicate, nitrate and nitrite, chlorophyll, transmissometer, PAR, C14 primary productivity, phytoplankton biodiversity, zooplankton biomass, and zooplankton biodiversity.
Note that each table has several dozen columns. Here is a link to the dataset