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feat(data): remove F5
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markwoon committed Mar 26, 2024
1 parent 558c4e3 commit 0c6123b
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2 changes: 0 additions & 2 deletions docs/Genes-and-Drugs.md
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Expand Up @@ -51,7 +51,6 @@ HLA calls, respectively, using sequencing data.
| Gene | CPIC | PharmGKB-DPWG |
| :--- | :---: | :---: |
| [CYP2D6](/Phenotypes-List#cyp2d6) | :heavy_check_mark: | :heavy_check_mark: |
| [F5](/Phenotypes-List#f5) | | :heavy_check_mark: |
| [HLA-A](/Phenotypes-List#hla-a) | :heavy_check_mark: | :heavy_check_mark: |
| [HLA-B](/Phenotypes-List#hla-b) | :heavy_check_mark: | :heavy_check_mark: |
| [MT-RNR1](/Phenotypes-List#mt-rnr1) | :heavy_check_mark: | |
Expand Down Expand Up @@ -104,7 +103,6 @@ The following table lists drugs for which PharmCAT has recommendations for, alon
| gentamicin | :heavy_check_mark: | |
| haloperidol | | :heavy_check_mark: |
| halothane | :heavy_check_mark: | |
| hormonal contraceptives for systemic use | | :heavy_check_mark: |
| hydrocodone | :heavy_check_mark: | |
| ibuprofen | :heavy_check_mark: | |
| imipramine | :heavy_check_mark: | :heavy_check_mark: |
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12 changes: 0 additions & 12 deletions docs/Phenotypes-List.md
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Expand Up @@ -165,18 +165,6 @@ If you are using [outside calls](/using/Outside-Call-Format), you can see how we
</tr>
</table>

### F5
<table>
<tr>
<th style="text-align: left">Variants</th>
<th style="text-align: left">DPWG Phenotypes</th>
</tr>
<tr>
<td style="vertical-align: top"><ul style="padding-left: 1rem"><li>rs6025 C</li><li>rs6025 T (Factor V Leiden)</li></ul></td>
<td style="vertical-align: top"><ul style="padding-left: 1rem"><li>Factor V Leiden absent</li><li>Factor V Leiden heterozygous</li><li>Factor V Leiden homozygous</li></ul></td>
</tr>
</table>

### G6PD
<table>
<tr>
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11 changes: 1 addition & 10 deletions docs/examples/pharmcat.example.match.html
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Expand Up @@ -147,15 +147,6 @@ <h3>DPYD</h3>
<tr><th class="first"></th><td>G</td><td>C</td><td>C</td><td>C</td><td>A</td><td>G</td><td>T</td><td>T</td><td>T</td><td>T</td><td>T</td><td>C</td><td>G</td><td>C</td><td>T</td><td>T</td><td>C</td><td>G</td><td>G</td><td>G</td><td>A</td><td>C</td><td>G</td><td>C</td><td>C</td><td>C</td><td>T</td><td>C</td><td>G</td><td>TG</td><td>A</td><td>A</td><td>C</td><td>C</td><td>G</td><td>C</td><td>A</td><td>T</td><td>C</td><td>C</td><td>G</td><td>C</td><td>C</td><td>T</td><td>G</td><td>G</td><td>G</td><td>G</td><td>G</td><td>A</td><td>C</td><td>C</td><td>A</td><td>C</td><td>C</td><td>G</td><td>C</td><td>T</td><td>G</td><td>C</td><td>C</td><td>C</td><td>G</td><td>A</td><td>T</td><td>T</td><td>G</td><td>T</td><td>T</td><td>T</td><td>C</td><td>C</td><td>T</td><td>T</td><td>T</td><td>C</td><td>GATGA</td><td>A</td><td>C</td><td>G</td><td>G</td></tr>
</table>

<h3>F5</h3>
<ul> <li>rs6025 C/rs6025 C (2)</li></ul>
<table class="table table-striped table-hover table-sm">
<tr><th class="first">Definition Position</th><th>169549811</th></tr> <tr><th></th><th>rs6025</th></tr> <tr><th class="first">VCF Position</th><th>169549811</th></tr> <tr><th class="first">VCF REF,ALTs</th><th>C,T</th></tr>
<tr class="table-success"><th class="first">VCF Call</th><th>C/C</th></tr>
<tr class="table-info"><th class="first">rs6025 C</th><td><b>C</b></td></tr>
<tr><th class="first"></th><td>C</td></tr>
</table>

<h3>G6PD</h3>
<ul> <li>B (reference)/B (reference) (342)</li></ul>
<table class="table table-striped table-hover table-sm">
Expand Down Expand Up @@ -234,7 +225,7 @@ <h3>VKORC1</h3>
<hr />
<footer class="container-fluid">
<p>
<small>Generated on 03/11/24.</small>
<small>Generated on 03/25/24.</small>
</p>
</footer>
</div>
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100 changes: 2 additions & 98 deletions docs/examples/pharmcat.example.match.json
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Expand Up @@ -3,7 +3,7 @@
"namedAlleleMatcherVersion": "2.0.0",
"genomeBuild": "GRCh38.p13",
"inputFilename": "pharmcat.example.vcf",
"timestamp": "2024-03-11T16:40:18.457Z",
"timestamp": "2024-03-26T04:55:24.238Z",
"topCandidatesOnly": true,
"findCombinations": false,
"callCyp2d": false
Expand Down Expand Up @@ -2958,7 +2958,7 @@
},
{
"source": "PHARMGKB",
"version": "2024-03-11-09-29",
"version": "2024-03-25-16-13",
"chromosome": "chr7",
"gene": "CYP3A4",
"diplotypes": [
Expand Down Expand Up @@ -5008,102 +5008,6 @@
"ignoredHaplotypes": [],
"warnings": []
},
{
"source": "PHARMGKB",
"version": "2024-03-11-09-29",
"chromosome": "chr1",
"gene": "F5",
"diplotypes": [
{
"name": "rs6025 C/rs6025 C",
"haplotype1": {
"name": "rs6025 C",
"haplotype": {
"name": "rs6025 C",
"id": "PA166300382",
"alleles": [
"C"
],
"cpicAlleles": [
"C"
],
"populationFrequency": null,
"reference": true,
"numCombinations": 0,
"numPartials": 0
},
"sequences": [
"169549811:C;"
]
},
"haplotype2": {
"name": "rs6025 C",
"haplotype": {
"name": "rs6025 C",
"id": "PA166300382",
"alleles": [
"C"
],
"cpicAlleles": [
"C"
],
"populationFrequency": null,
"reference": true,
"numCombinations": 0,
"numPartials": 0
},
"sequences": [
"169549811:C;"
]
},
"score": 2
}
],
"haplotypes": [
{
"name": "rs6025 C",
"haplotype": {
"name": "rs6025 C",
"id": "PA166300382",
"alleles": [
"C"
],
"cpicAlleles": [
"C"
],
"populationFrequency": null,
"reference": true,
"numCombinations": 0,
"numPartials": 0
},
"sequences": [
"169549811:C;"
]
}
],
"haplotypeMatches": [],
"phased": false,
"variants": [
{
"position": 169549811,
"rsid": "rs6025",
"vcfCall": "C/C",
"phased": false
}
],
"variantsOfInterest": [],
"matchData": {
"missingPositions": [],
"positionsWithUndocumentedVariations": [],
"treatUndocumentedVariationsAsReference": false,
"phased": false,
"homozygous": true,
"effectivelyPhased": true
},
"uncallableHaplotypes": [],
"ignoredHaplotypes": [],
"warnings": null
},
{
"source": "CPIC",
"version": "v1.38.0-1-g39f50e7",
Expand Down
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