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# The Isoform-centric Microglia Genomic Atlas (isoMiGA) Project

Jack Humphrey, Erica Brophy, Towfique Raj lab 2023
Jack Humphrey, Erica Brophy, Towfique Raj lab

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## Manuscript

In progress
[Preprint on MedRxiv](https://github.com/RajLabMSSM/isoMiGA)

## Raw Data

[All Long-read data](https://www.synapse.org/#!Synapse:syn52052829)

[Gaffney short-read cohort](https://ega-archive.org/datasets/EGAD00001005736)

[Raj short-read microglia samples](https://dss.niagads.org/datasets/ng00105/)

[Roussos short-read batch 1](https://doi.org/10.7303/syn26207321)

[Roussos short-read batch 2](https://www.synapse.org/#!Synapse:syn52052829)

[Stimulated IMGL short-read](https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE240907)

## Processed Data

[Novel isoform GTF and FASTA](https://zenodo.org/record/8290956)

[Count matrices for all cohorts](https://zenodo.org/record/8291211)

[All QTL summary statistics](https://zenodo.org/record/8250771)

## Pipelines

Short-read RNA-seq processing: https://github.com/CommonMindConsortium/RAPiD-nf
[Short-read RNA-seq processing]( https://github.com/CommonMindConsortium/RAPiD-nf)

Long-read RNA-seq processing: https://github.com/RajLabMSSM/isoseq-pipeline
[Long-read RNA-seq processing](https://github.com/RajLabMSSM/isoseq-pipeline)

QTL mapping and meta-analysis: https://github.com/RajLabMSSM/mmQTL-pipeline
[QTL mapping and meta-analysis](https://github.com/RajLabMSSM/mmQTL-pipeline)

Genotype quality control: https://github.com/RajLabMSSM/Genotype_QC_Pipeline_2.0
[Genotype quality control](https://github.com/RajLabMSSM/Genotype_QC_Pipeline_2.0)


## Long-read RNA-seq isoforms
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