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Sorry, there was an error in the contigmap definition, I have fixed it and now works fine! |
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Hi, awesome method many thanks for sharing. I am trying to apply RF diffusion to scaffold a motif of a PPI, similar to what you do for the p53 helix in the paper. However, I find out that most of the designs, although they efficiently scaffold the PPI segment, they produce clashes with the target protein. Do you know what might be the reason? Would it be possible to have access to the code you use to generate the MDM2 binders using this strategy? Thanks!!
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