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Surveys of IEDB Experimental Types
Gully Burns edited this page Jun 28, 2017
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IEDB uses implicit, heuristic templates to provide a pragmatic modeling approach for surveying the literature over a large number of different experimental studies involving immunoepitopes.
These seem to fall into the same overall structure from examination of the tcell and bcell tables
These types and subtypes fall into the following high-level categories:
- Administration in vivo
- Administration in vivo to cause disease
- Administration in vivo to prevent or reduce disease
- Exposure without evidence for disease
- Documented exposure without evidence for disease
- Environmental exposure to endemic/ubiquitous agent without evidence for disease
- Exposure with existing immune reactivity without evidence for disease
- No immunization
- Occurrence of <X>
- Occurrence of allergy
- Occurrence of disease
- Occurrence of autoimmune disease
- Occurrence of cancer
- Occurrence of infectious disease
- Transplant/transfusion
- Unknown
On the IEDB Study Papers page, we are working through the example provided by Richardson et al 1998, PMID9499101 to examine an example Administration in vivo
protocol as a way of looking at this. The goal will be to extend this simple model to include other protocol types.