Pitfalls and opportunities for applying latent variables in single-cell eQTL analyses [analysis code]

This repository contains the analysis code pipeline to generate latent variables from pseudo-bulk data and perform eQTL association analysis as part of the manuscript "Pitfalls and opportunities for applying latent variables in single-cell eQTL analyses"

Citation: Angli Xue, Seyhan Yazar, Drew Neavin, Joseph E. Powell. Pitfalls and opportunities for applying latent variables in single-cell eQTL analyses. Genome Biology. 2023. [Full text]