### Is this a regression? - [ ] Yes, this behavior used to work in the previous version ### The previous version in which this bug was not present was _No response_ ### Description The callback applied to the `closed` EventEmitter seems to run outside of the Angular Zone when `closed` is emitted via "outside click" ### Reproduction https://stackblitz.com/edit/components-issue-83t6vu?file=src/app/autocomplete.component.ts Steps to reproduce: 1. click inside input - should open panel and disable button 2. click outside panel to close it - expect button to be enabled, but remains disabled ### Expected Behavior clicking outside the panel to close the panel should have disabled the button without using `ngZone.run()` ### Actual Behavior the button remains disabled ### Environment - Angular: 13.3.0 - CDK/Material: 13.3.0 - Browser(s): Chrome - Operating System (e.g. Windows, macOS, Ubuntu): macOS