Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Add clipping heuristic to indel realigner #63

Closed
fnothaft opened this issue Jan 27, 2014 · 1 comment
Closed

Add clipping heuristic to indel realigner #63

fnothaft opened this issue Jan 27, 2014 · 1 comment

Comments

@fnothaft
Copy link
Member

Currently, the indel realigner code unclips all reads when locally realigning. This is OK (we won't wind up with worse alignments) but we may be missing out on the opportunity to realign some reads. I believe that we could have a clipping heuristic that would improve this—something like whether the base was previously clipped and has a low quality score.

@fnothaft
Copy link
Member Author

Closing as won't fix. We will probably EOL the indel realigner post 1.0.0.

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Projects
None yet
Development

No branches or pull requests

1 participant