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Memory requirement for ~100k cells RNA+ATAC #32

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wlason opened this issue Aug 16, 2024 · 1 comment
Open

Memory requirement for ~100k cells RNA+ATAC #32

wlason opened this issue Aug 16, 2024 · 1 comment

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@wlason
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wlason commented Aug 16, 2024

Hi! I am trying to use your package to integrate a dataset of RNA + ATAC, it is approximately 100k cells. I keep having issues with jobs getting OOM killed. So far I have tested up to 20 CPUs, 500GB RAM, but no luck, so I was wondering if you have done any testing and could give me an indication of how much memory I would need.

@gtca
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gtca commented Oct 17, 2024

Hey @wlason,

What is the amount of features you're using there as input? One way to make it work has been using only a subset of highly variable features. You can also try lower precision, i.e. float32, which should be the default now.

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