non-SV filtering

[torakichi1219]

Hi,

After using smoove to extract SVs for the trio, we attempt to use slivar on them to extract denovo-SVs.
For example, mom:0/0, dad:0/0 -> kid:0/1 or 1/1 as denovo-SV. I use DHFFC < 0.7 for filtering DEL and DHFFC > 1.25 for filtering DUP. Is there any filtering for the part without SV (the 0/0 part)?
I would appreciate it if you could enlighten me.

best,
tora

[brentp]

Hi sorry for the delay. I think using the DHFFC is the best filter, along with genotype.

[torakichi1219]

Thank you.
Now I will try to filter using DHFFC.